Multilevel research strategies characterize contemporary molecular inquiry into biological systems. We outline conceptual, methodological, and explanatory dimensions of these multilevel strategies in microbial ecology, systems biology, protein research, and developmental biology. This review of emerging lines of inquiry in these fields suggests that multilevel research in molecular life sciences has significant implications for philosophical understandings of explanation, modeling, and representation.

Numerous writers have recently called for reform in psychological theorizing and research methodology designed to appreciate the teleological, active agent capacities of humans. This paper presents three studies that probe individual's abilities to volitionally control their eating behavior. These investigations suggest one way that researchers might consider the operation of telic powers in human action. Rather than seeing teleological explanations as rivals to the more traditional causal explanations favored in psychological research, this paper elaborates a position that sees (...) human volition as a causal force embedded in the traditional causal influences studied in psychological research. Finally, the theoretical and methodological refinements suggested here and elsewhere are seen against the backdrop of a philosophy of science that sees change as a more gradual, evolutionary process, rather than the Kuhnian, revolutionary process. (shrink)

Contemporary philosophy of science has seen a growing trend towards a focus on scientific practice over the epistemic outputs that such practices produce. This practice-oriented approach has yielded a clearer understanding of how reductive research strategies play a central role in contemporary scientific inquiry. In parallel, a growing body of work has sought to explore the role of non-reductive, or systems-level, research strategies. As a result, the relationship between reductive and non-reductive scientific practices is becoming of (...) increased importance. In this paper, I provide a framework within which research strategies can be compared. I argue that no strategy is reductive or non-reductive simpliciter, rather strategies are more, or are less, reductive than one another according to a frame of reference. That frame of reference is provided by a continuum of possible ways in which the target system might be conceptualised. I illustrate the utility of the framework by deploying it to analyse a recent debate in cancer research. When set within the framework, a prominent reductive strategy—the somatic mutation theory—and a prominent non-reductive strategy—the tissue organisational field theory—do not stand opposed to one another. Rather, they serve as boundary markers to chart the territory of approaches to carcinogenesis within which most strategies in the field fall. (shrink)

Marr’s seminal distinction between computational, algorithmic, and implementational levels of analysis has inspired research in cognitive science for more than 30 years. According to a widely-used paradigm, the modelling of cognitive processes should mainly operate on the computational level and be targeted at the idealised competence, rather than the actual performance of cognisers in a specific domain. In this paper, we explore how this paradigm can be adopted and revised to understand mathematical problem solving. The computational-level approach applies methods (...) from computational complexity theory and focuses on optimal strategies for completing cognitive tasks. However, human cognitive capacities in mathematical problem solving are essentially characterised by processes that are computationally sub-optimal, because they initially add to the computational complexity of the solutions. Yet, these solutions can be optimal for human cognisers given the acquisition and enactment of mathematical practices. Here we present diagrams and the spatial manipulation of symbols as two examples of problem solving strategies that can be computationally sub-optimal but humanly optimal. These aspects need to be taken into account when analysing competence in mathematical problem solving. Empirically informed considerations on enculturation can help identify, explore, and model the cognitive processes involved in problem solving tasks. The enculturation account of mathematical problem solving strongly suggests that computational-level analyses need to be complemented by considerations on the algorithmic and implementational levels. The emerging research strategy can help develop algorithms that model what we call enculturated cognitive optimality in an empirically plausible and ecologically valid way. (shrink)

Bayesian reverse-engineering is a research strategy for developing three-level explanations of behavior and cognition. Starting from a computational-level analysis of behavior and cognition as optimal probabilistic inference, Bayesian reverse-engineers apply numerous tweaks and heuristics to formulate testable hypotheses at the algorithmic and implementational levels. In so doing, they exploit recent technological advances in Bayesian artificial intelligence, machine learning, and statistics, but also consider established principles from cognitive psychology and neuroscience. Although these tweaks and heuristics are highly pragmatic in character (...) and are often deployed unsystematically, Bayesian reverse-engineering avoids several important worries that have been raised about the explanatory credentials of Bayesian cognitive science: the worry that the lower levels of analysis are being ignored altogether; the challenge that the mathematical models being developed are unfalsifiable; and the charge that the terms ‘optimal’ and ‘rational’ have lost their customary normative force. But while Bayesian reverse-engineering is therefore a viable and productive research strategy, it is also no fool-proof recipe for explanatory success. (shrink)

For a long time, large-scale urbanexpansion has dominated the nature of the urban environment. In our times however, planners are often dealing with maintenance, modification, and redevelopment of urban situations that alreadyexist. Which are the implications of this fundamental change for theories and strategies of urban planning and design?

The paper explores the distinction between two doctrines, both of which inform theory construction in much of modern cognitive psychology: the representational theory of mind and the computational theory of mind. According to the former, propositional attitudes are to be construed as relations that organisms bear to mental representations. According to the latter, mental processes have access only to formal (nonsemantic) properties of the mental representations over which they are defined.The following claims are defended: (1) That the traditional dispute between (...) “rational” and “naturalistic” psychology is plausibly viewed as an argument about the status of the computational theory of mind. Rational psychologists accept a formality condition on the specification of mental processes; naturalists do not. (2) That to accept the formality condition is to endorse a version of methodological solipsism. (3) That the acceptance of some such condition is warranted, at least for that part of psychology which concerns itself with theories of the mental causation of behavior. This is because: (4) such theories require nontransparent taxonomies of mental states; and (5) nontransparent taxonomies individuate mental states without reference to their semantic properties. Equivalently, (6) nontransparent taxonomies respect the way that the organism represents the object of its propositional attitudes toitself, and it is this representation which functions in the causation of behavior.The final section of the paper considers the prospect for a naturalistic psychology: one which defines its generalizations over relations between mental representations and their environmental causes, thus seeking to account for the semantic properties of propositional attitudes. Two related arguments are proposed, both leading to the conclusion that no such research strategy is likely to prove fruitful. (shrink)

The anomalous experiences of shamans have been reported over the centuries, but only recently have they been subjected to rigorous investigation. Although interviews, reports, and informal observations can produce interesting material, their anomalous nature can only be determined by controlled observations and experimental studies. Examples of each are given and recommendations are made for further research.

Functionalists in philosophy of mind traditionally raise two major arguments against the type identity theory: (1) psychological states are _multiply realizable_ so that there are no one-to-one mappings of psychological states onto neural states and (2) the most that evidence could ever establish is the _correlation_ of psychological and neural states, not their identity. We defend a variant on the traditional type identity theory which we call _heuristic identity theory_ (HIT) against both of these objections. Drawing its inspiration from scientific (...) practice, heuristic identity theory construes identity claims as hypotheses that guide subsequent inquiry, not as conclusions of the research. (shrink)

The paper argues that renormalization in quantum field theory was not a radically new - and possibly ad hoc - technique to save a badly flawed theory, but rather the culmination of a methodological strategy that physicists had been applying for a long time. The strategy was to obtain reliable results from unreliable theories by making the derivation of the results independent of possible future modifications of the theory. Examples of this practice include Bohr's use of the Correspondence Principle and (...) Heisenberg's S-matrix theory. (shrink)

The U.S. military is developing augmented reality (AR) capabilities for use on the battlefield as a means of achieving greater situational awareness. The superimposition of digital data—designed to expand surveillance, enhance geospatial understanding, and facilitate target identification—onto a live view of the battlefield has important implications for virtuous conduct in war: Can the soldier exercise practical wisdom while integrated into a system of militarized legibility? Adopting a virtue ethics perspective, I argue that AR disrupts the soldier’s immersion in the scene (...) such that he is blinded to features beyond those identified in advance by the military’s system of cybernetic judgment. I turn to Michael Walzer’s classic account of the “naked soldier” dilemma to illustrate how AR capabilities radically shrink the bounds within which the soldier can cultivate the capacity for right conduct. By transforming the ambiguous ethical matter of killing an enemy combatant into the straightforward application of a rule, AR hollows out the soldier’s potential for virtuous action. The “smart battlefield” leaves no space for deliberative judgments that transcend the technical and legal determinations already written into the soldier’s view of the scene. (shrink)

InTowards a Canadian Research Strategy ForApplied Ethics, I put forward proposals to advance Canadian research in applied ethics. I focus on the assessment made of Canadian teaching, consulting, and research in business and professional ethics and then on the strategy proposed for advancing work in these areas. I argue for research which is [1] oriented to the ethical needs of those in business and the professions, [2] interdisciplinary, and [3] involves the creation of national and international (...) networks. I then offer some preliminary observations on the first two years of the new research strategy''s operation. (shrink)

The experimental method is designed to secure the reliable attribution of causal relationships by means of controlled comparison across conditions. Doing so, however, depends upon the reduction of uncertainties and inconsistencies in the process of comparison; and this poses particularly significant challenges for the behavioral and social sciences because they work with human subjects, whose malleability and complexity often interact in unexpected ways with experimental manipulations, thus resulting in unpredictable behavior. Drawing on the Science and Technology Studies perspective and one (...) of our authors’ experiences in experimental work, this paper examines how experimental social scientists manage to establish objectivity and standardization in the face of vagaries arising from working with human subjects. In identifying experimental researchers’ solutions to this challenge, we draw on methodological discussions among applied social scientists as naturally occurring data, through which we show how some seemingly mundane practices play essential roles in extracting patterns out of otherwise unpredictable behaviors in the lab. Closely examining such strategies, we reveal the inherent instabilities in the experimental method when adopted in the social sciences and discuss their methodological implications. In conclusion, we make tentative suggestions for escaping the kinds of methodological impasses which we have identified. (shrink)

The biological sciences study (bio)complex living systems. Research directed at the mechanistic explanation of the "live" state truly requires a pluralist research program, i.e. BioComplexity research. The program should apply multiple intra-level and inter-level theories and methodologies. We substantiate this thesis with analysis of BioComplexity: metabolic and modular control analysis of metabolic pathways, emergence of oscillations, and the analysis of the functioning of glycolysis.

Intensive investigations into female entrepreneurships are a relatively recent research phenomenon. Advances in the past five years, while dramatic, find the field in an initial stage of paradigm development. Individual studies appear fragmented, unrelated, and seem to describe only small segments of the female entrepreneurial population and more frequently than not apply theoretical tools developed in other areas which are neither reliable or valid. This article examines a number of current research and methodological issues, presents a descriptive analysis (...) of the traditional and modern female entrepreneur, suggests focal areas for research oriented toward the establishment of typologies, models and theory development. (shrink)

Many research-intensive universities have moved into the business of promoting technology development that promises revenue, impact, and legitimacy. While the scholarship on academic capitalism has documented the general dynamics of this institutional shift, we know less about the ground-level challenges of research priority and scientific problem choice. This paper unites the practice tradition in science and technology studies with an organizational analysis of decision-making to compare how two university artificial intelligence labs manage ambiguities at the edge of scientific (...) knowledge. One lab focuses on garnering funding through commercialization schemes, while the other is oriented to federal science agencies. The ethnographic comparison identifies the mechanisms through which an industry-oriented lab can be highly adventurous yet produce a research program that is thin and erratic due to a priority placed on commercialization. However, the comparison does not yield an implicit nostalgia for federalized science; it reveals the mechanisms through which agency-oriented labs can pursue a thick and consistent research portfolio but in a strikingly myopic fashion. (shrink)

The article concerns the definition of the problem field of a new type of modern terrorist activity in the information space under the conditions of globalization - information terrorism.The findings systematized, which are presented in the domestic social and political discourse and can serve as the basis for its further comprehensive research in the direction of building its corresponding model / concept. The research strategy of the well-known American methodologist L. Coser used for the analysis of elements of (...) social reality - the search for a set of interrelated indicators (variables) that can clarify the content, conditions for the emergence and development of this research subject.It substantiated that when constructing the problem field of the analysis of information terrorism as an element of social reality, such indicators can be: first, the interpretation of the very concept of «information terrorism»;secondly, the analysis of the causes and conditions of the spread of terrorist activity in the information space; thirdly, the classification of the main forms of manifestation of information terrorism; fourth, the analysis of the main technologies and methods of carrying out terrorist activities of an informational nature; fifth, substantiation of conditions and development of mechanisms against the wide spread of information terrorism in the modern world.The analysis of the essence of information terrorism from the standpoint of constructing an analytical (five-link) scheme for researching the problematic field of this type of terrorist activity provides a basis for generalizing and interpreting this new form of terrorism as the use of information and information infrastructure by certain (states, organizations, structures), on the one hand, for violence against people’s consciousness, manipulation of their behavior using certain methods and methods of influence, and on the other hand – to influence the information and technical structure of the state, with the aim of exerting pressure on the adoption of favorable decisions by states, groups of people or individuals by creating conditions for chaos, panic, etc. (shrink)

Current computational psychology, especially as described by Fodor (1975, 1980, 1981), Pylyshyn (1980), and Stich (1983), is both a bold, promising program for cognitive science and an alternative to naturalistic psychology (Putnam 1975). Whereas naturalistic psychology depends on the general scientific framework to fix the meanings of general terms and, hence, the content of thoughts utilizing or expressed in those terms, computational cognitive theory banishes semantical considerations in psychological investigations, embracing methodological, not ontological, solipsism. I intend to argue that computational (...) psychology cannot individuate thoughts as it promises. For, semantics is fundamental in fixing an important subset of the computational relations that, according to the computational theory, are supposed both to obtain among thoughts and, thereby, to determine their identity conditions. If what I contend is correct, then contrary to what its advocates maintain, computational psychology is not preferable to naturalistic psychology as a research strategy in cognitive science. (shrink)

Introducción: La asignatura Metodología de la Investigación Cualitativa en Salud se imparte a los estudiantes de tercer año de la Licenciatura en Enfermería en la modalidad de clase teórico-práctica como forma organizativa de la docencia. Ello recalca la importancia del trabajo independiente. Las insuficiencias con relación a éste inciden directamente en la asimilación y apropiación de los conocimientos de la asignatura. Objetivo: Elaborar una estrategia didáctica que contribuya al desarrollo del trabajo independiente correspondiente a la asignatura Metodología de la Investigación (...) Cualitativa en Salud.Material y métodos: Se realizó una investigación de desarrollo, encaminada a perfeccionar el proceso docente educativo en la Facultad de Enfermería, de la Universidad de Ciencias Médicas de Camagüey, durante el curso escolar 2011-2012. Para el diagnóstico inicial se procedió al análisis de documentos: los planes de estudio y el programa de la asignatura. También se aplicaron encuestas a un grupo de estudiantes y al colectivo de profesores que imparten la asignatura. Una vez elaborada la estrategia se evaluó por criterio de expertos. Resultados y discusión: La estrategia pone a disposición de la comunidad académica un software educativo que relaciona los contenidos de la asignatura, lo que permitirá al estudiantado realizar las tareas docentes que se orientan en clases así como asimilar, consolidar y sistematizar los conocimientos con mayor facilidad. Introduction: The subject Methodology of Qualitative Research in Health is taught to the students of the third year of the Bachelor in nursing in the form of theoretical and practical lesson as organizational way of teaching. This underscores the importance of self-employment. The shortcomings in relation to this affect directly the assimilation and appropriation of knowledge in the subject. Objective: To develop a teaching strategy that contributes to the development of self-employ ment for the subject Methodology of Qualitative Research in Health. Material aids and methods: A development research was made which aims at improving the educational teaching process in the Faculty of nursing from the University of Medical Sciences in Camagüey, during the 2011-2012 course. For an initial diagnosis the analyses of documents was made: the curriculum and the program of the course. Surveys were also applied to a group of students and the staff of teachers of the subject. Once the strategy was made it was evaluated through criteria of experts. Results and discussion: Strategy makes available to the academic community educational software that relates to the contents of the course, allowing students to perform teaching tasks which are assigned in lessons as well as assimilate, consolidate and systematize the knowledge easiest. (shrink)

Scientific tradition holds that it is essential to permit individual researchers almost complete freedom in their selection of research projects. As a result, structured research planning has not played a major role in determining the course of the sciences. By “structural research planning” we mean the methodical establishment of goals, and the identification of research routines which apparently accord priority to highest value goals, while minimizing the cost and time of their attainment. With increasing competition for (...) limited fiscal and intellectual resources this kind of planning may become more necessary. Let us cite three specific examples: First, the individual researcher is often faced with the question of how best to spend his time in pursuing a particular line of investigation. He must allocate his personal resources of time and talent to work which appears to hold the promise of highest pay-off. Second, on a larger scale, the competition for resources also raises the question of priority among alternative government-sponsored research projects. Individuals proposing equally alluring projects sometimes seek the same funds; government planners need some sort of objective criteria in order to judge the proposals. Furthermore, government planners face the problem of justifying their request for “big science” resources; a planning strategy which defines the use and expected output of the requested resources can help in the design and promotion of their concept. Finally, there is a growing sentiment that at least some research should be directed toward the solution of current and anticipated societal problems, to find means of circumventing or minimizing the impact of potentially dangerous problems of civilization. These needs : the choice of individual research, allocation of national resources among competing projects, and selecting research of societal importance, suggest that structured research planning might be valuable. (shrink)

The article examines the process of niche standardization in medical research as an example of democratizing strategies implemented in industry-funded science. I argue that niche standardization can lead to undesirable epistemic and ethical consequences, if the various goals of research are not properly aligned. I examine two examples: the case of Sarafem, approved for the treatment of premenstrual dysphoric disorder in women, and the case of BiDil, approved for exclusive use in African Americans for the treatment of (...) congestive heart failure. I conclude by cautioning against the unqualified support of democratizing strategies in industry-funded research. (shrink)

In the Chinese society, border agents in channel transactions will choose different opportunistic behavior response strategies to the tolerance of other members based on the relationship between the two parties. Based on 206 valid questionnaires collected, structural equation model and regression analysis were used to investigate the influence of opportunistic behavior tolerance on response strategy selection. The results show that the channel boundary personnel's tolerance to opportunistic behavior negatively influences their choice of a positive response strategy and positively influences (...) their choice of a negative response strategy. Among the mediating effects of contract formulation, transaction terms have a positive effect on the choice of negative response strategies based on the work and individual opportunistic behavior tolerance and have no mediating effect on the choice of positive response strategies; the contingency clause has no mediating effect on the choice of positive response strategies based on individual opportunistic behavior tolerance. (shrink)

Since the Millennium Ecosystem Assessment in 2005, interest has increased in cultural ecosystem services (CESs) research to understand the complexity of the non-material benefits that people obtain from ecosystems. The intangible and interactive characteristics of CESs present many challenges regarding how to approach, quantify and even define CESs. In this paper, we suggest looking at CESs through the lens of embodied and situated cognition theories. We advocate that such an approach should be applied to the development stage of CES (...) research projects, as the embodied and situated experience of the site aids the development of research questions and future interventions. We described a case study—namely, the Environmental Empathy Research Challenge, which took place during the ColLaboratoire 2020 Research Residency in the Philippines. This case shows how interactive, embodied and situated workshops, such as Embodied Empathy and Walking Maps, contributed to developing a research proposal and a novel research framework, ecological embodied cognition (EEC). EEC focuses on the concept of environmental empathy to redefine the human-environment relationship. Further, based on an example of a participatory research activity, Sensing-Playing-Moving, we examined how interventions founded upon EEC principles enhance environmental empathy. (shrink)

With increasing flexibility of technology and a shift towards competence being the core of competitive edge in worklife, the need for new organizational concepts or models which givejoint optimization across human and technological dimensions has been acknowledged in leading, innovative enterprises. National crossdisciplinary research based productivity programmes are appearing in several countries. Due to internationalization and the general shortcomings of bureaucratic organizational forms, regional networks of enterprises in cooperation with public R&D institutions seem to provide answers to needs of (...) regions to remain competitive. The paper discusses the possible role of social science in a multilevel, participative strategy for developing new, democratic and productive organizational forms in worklife. Aspects of national productivity programmes in Scandinavia, Germany and Australia are discussed in connection with the situation in Italy as analyzed through some recent research projects. (shrink)

In theory, HREC members should use the ethical guidelines in the National Statement on the Ethical Conduct of Research Involving Humans as the basis for their decisions, and researchers should design their research in accordance with these guidelines However, very little is known about what researchers and HREC members actually do in practice. In this paper, we report some of the key findings of the study “Human Research Ethics in Practice”, a qualitative interview-based study of health researchers (...) and HREC members in Victoria. The findings shed light on how researchers and HREC members conceptualise ethics, how they use the National Statement, and what deliberative strategies they employ to assess the ethical appropriateness of research studies. The findings also reveal differences and similarities between health researchers’ and HREC members’ perceptions of the roles of HRECs, and point to some sources of misunderstanding and tension. We examine the implications of some of these findings for the ways in which HRECs carry out their task, and research institutions support and promote ethical conduct in research amongst their staff and students. The focus of this study is on health research, but we suggest that the findings are highly relevant to all other research areas where human participants are involved. (shrink)

The sociology of research and knowledge use, argue the authors, could be a way of linking important parts of sociology, such as organization studies, the sociology of science to each other. In the article, they discuss the idea that organizational responses to environments are related to research utilization. Based upon an empirical investigation of city welfare departments, four empirical “utilization strategies” are presented and shown to be related to power and control patterns. While negative utilization strategies (...) are hostile to uncontrolled research utilization and enhance the formation of bureaucratic expertise, conflict-oriented strategies are discursively productive and reinforce research use and alliance formation with social scientists to control the environment. (shrink)

In Australia, along with many other countries, limited guidance or other support strategies are currently available to researchers, institutional research ethics committees, and others responsible for making decisions about whether to return genomic findings with potential value to participants or their blood relatives. This lack of guidance results in onerous decision-making burdens—traversing technical, interpretative, and ethical dimensions—as well as uncertainty and inconsistencies for research participants. This article draws on a recent targeted consultation conducted by the Australian National (...) Health and Medical Research Council to put forward strategies for supporting return of finding decision-making. In particular, we propose a pyramid of decision-making support: decision-making guidelines, technical and interpretative assistance, and ethical assistance for intractable “tough” cases. Each step of the pyramid involves an increasing level of regulatory involvement and applies to a smaller subsection of genomic research findings. Implementation of such strategies would facilitate a growing evidence base for return of finding decisions, thereby easing the financial, time, and moral burdens currently placed on researchers and other relevant decision-makers while also improving the quality of such decisions and, consequently, participant outcomes. (shrink)