There is no doubt that slurs harm. They do so by denigrating their targets, by putting them down, by marginalizing them. This is why in many legislations around the world, the use of slurs has been banned or penalized. But should all uses of slurs be banned? Many uses of slurs are non-derogatory and seem to have beneficial effects. However, such uses are double-faceted: as both armchair reflection and experimental studies have shown, they are able to produce harm as well. (...) In this paper, I approach the broad question of whether all non-derogatory uses of slurs should be banned. I first present the main uses of slurs that have been considered to be non-derogatory and recent reactions to those. The upshot of this survey is that uses of slurs that have been considered non-derogatory do, in fact, produce harm. I also flag what various authors have recommended in relation to the issue of banning such uses. Against this background, I engage with a recent view put forward by Alba Moreno Zurita and Eduardo Pérez-Navarro, who urge extreme caution with respect to any uses of slurs, due to their potential to normalize derogation. After presenting their view and their main argument, I raise an objection related to their treatment of neutral uses of slurs. I end with pointing out that, while their endeavour has merit in that it pushes the discussion further, it raises certain issues that need addressing, both empirical and normative. (shrink)

Tait's proof of strong normalization for the simply typed λ-calculus is interpreted in a general model theoretical framework by means of the specification of a certain theory T and a certain model /oU of T. The argumentation is partly reduced to formal predicate logic by the application of certain derivability properties of T. The resulting version of Tait's proof is, within the same framework, systematically generalized to the Calculus of Constructions and other advanced type systems. The generalization proceeds along (...) the formal level in the sense that T is modified first and that the new theory partly dictates the subsequent transformation of /oU, which is carried out in stages. The uniform and standardized character of the argumentation contributes to its perspicuity. (shrink)

This article illustrates ways in which the concepts of the norm and normativity are implicated in relations of power. Specifically, I argue that these concepts have come to function in a normalizing manner. I outline Michel Foucault’s thinking on the norm and normalization and then provide an overview of Jürgen Habermas’s thinking on the norm and normativity in order to show that Habermas’s conceptualizations of the norm and normativity are not, as he posits, necessary foundations for ethics and politics, (...) but in fact simply one philosophical approach among many. Uncritically accepting a Habermasian framework therefore produces normalizing effects and inhibits alternative and potentially emancipatory thinking about ethics and politics. Having problematized the requirement of normative foundations as it is currently articulated, I conclude by examining the emancipatory potential of a particular aspect of Foucault’s work for the practice of philosophy. (shrink)

Against any obscurantist stand, denying the interest of natural sciences for the comprehension of human meaning and language, but also against any reductionist hypothesis, frustrating the specificity of the semiotic point of view on nature, the paper argues that the deepest dynamic at the basis of meaning consists in its being a mechanism of ‘potentiality navigation’ within a universe generally characterized by motility. On the one hand, such a hypothesis widens the sphere of meaning to all beings somehow endowed with (...) the capacity of moving and/or perceiving movement. On the other hand, through a new evolutionist interpretation of the concept of generativity, such a hypothesis preserves the peculiarity of human meaning, meant as essentially founded on a certain intuition of infinity. Two corollaries stem from this hypothesis: first, religiosity can be considered as a matrix of grammars of infinity, aiming at regimenting its flight of potentialities. Second, non-genetic transmission of cultural information exerts determinant influence also at the level of that very deep mechanism of the human predicament that is the cognitive navigation of motor potentialities. A re-reading of the structuralist epistemology, scientific literature on the nervous cells of jellyfish, and some recent experiments on the mirror neurons of dancers, as well as certain intuitions of Teilhard de Chardin, are the main arguments of the paper. (shrink)

This article challenges an important argument in the abortion debate, according to which at least early abortions are acceptable because they do not terminate the actual existence of something of moral significance (i.e., a ‘person’), but rather prevent a potentially significant entity from becoming actual, which happens whenever one uses contraceptives.This article argues that insofar as we see something as morally significant or valuable, we tend to think it wrong to deliberately terminate its actual existence and to deliberately prevent (...) a corresponding potential entity from becoming actual, a principle I call the ‘Inverse Proportional Value Principle’. After defending this principle and showing it to oppose the idea that abortion is acceptable since it simply prevents the existence of something of moral worth or value, I show this principle to sanction some abortions, given that the entity which stands to result from a pregnancy is sufficiently lacking in value. (shrink)

Modal potentialism as proposed by Barbara Vetter (2015) is the view that every possibility is grounded in something having a potentiality. Drawing from work by Jessica Leech (2017), Samuel Kimpton-Nye (2021) argues that potentialists can have an S5 modal logic. I present a novel argument to the conclusion that the most straightforward way of spelling out modal potentialism cannot validate an S5 modal logic. Then I will propose a slightly tweaked version of modal potentialism that can validate an S5 (...) modal logic and still does justice to the core claim of potentialism. (shrink)

Einstein's linear Lagrangian is replaced by a Lagrangian which is quadratic in the curvature quantities (gauge invariance). The hypothesis is made that the basic metrical field is highly agitated (due to periodic boundary conditions) thus establishing a submicroscopic basic lattice structure of the space-time world which, however, is macroscopically isotropic. All consequences follow from these assumptions. The “free vector” of Einstein's theory (void of physical significance and used for the normalization of the reference system) is no longer free but (...) of physical significance. It becomes subject to the wave equation and the Lorentz condition. It can thus be identified with the electromagnetic vector potential. Although the present investigation does not go beyond the linear approximation, the contours of auniverse of maxium rationality emerge. (shrink)

ABSTRACT This paper examines three arguments that use the concept of potential to identify embryos that are morally suitable for embryonic stem cell research (ESCR). According to the first argument, due to Ronald Green, the fact that they are scheduled for disposal makes embryos left over from IVF treatments morally appropriate for research. Paul McHugh argues that embryos created by somatic cell nuclear transfer differ from those that result directly from the meeting of sperm and egg in having (...) potential especially conducive to the therapeutic use of their stem cells. I reject both of these arguments. According to the way of making distinctions in embryonic potential that I defend, it is the absence of a functional relationship with a womb that marks embryos morally suitable for ESCR. (shrink)

In [9], Newton da Costa together with the author of this paper argued in favor of the possibility to consider quantum superpositions in terms of a paraconsistent approach. We claimed that, even though most interpretations of quantum mechanics attempt to escape contradictions, there are many hints that indicate it could be worth while to engage in a research of this kind. Recently, Arenhart and Krause [1, 2, 3] have raised several arguments against this approach and claimed that —taking into account (...) the square of opposition— quantum superpositions are better understood in terms of contrariety propositions rather than contradictory propositions. In [14] we defended the Paraconsistent Approach to Quantum Superpositions and provided arguments in favor of its development. In the present paper we attempt to analyze the meanings of modality, potentiality and contradiction in QM, and provide further arguments of why the PAQS is better suited, than the Contrariety Approach to Quantum Superpositions proposed by Arenhart and Krause, to face the interpretational questions that quantum technology is forcing us to consider. (shrink)

In this paper, I outline the argument of my book "Potentiality: from dispositions to modality". The paper is part of a symposium on the book (in German).

Part of the normalization of assisted reproductive technologies is the premise that the children born from in vitro fertilization are no different from their counterparts conceived spontaneously. However, interest in peri-conception health and new epigenetic understandings of biological plasticity has led to some questioning the presumed irrelevance of conception in vitro, and when doing so, describing IVF children as “apparently healthy.” Taking “apparently” and “healthy” seriously, this article explores how modes of attention—ways of naming and framing embryo potentiality—shape understandings (...) of health and normality. I contend that understanding the politics of potentiality, and how they may emerge in a postgenomic age, requires an unpacking of various modes of attention and framing. Ethnographic findings from South Africa’s fertility clinics and emerging literature on epigenetic variation in IVF conception demonstrate how, under a genetic mode of attention, IVF clinics views “abnormality” as fated, unviable, and discardable. Exploring the possibility of answering the postgenomic questions to IVF reveals structural challenges to knowing long-term health implications. Incipient attempts within the fertility clinic at managing these questions shows various strategic techniques, such as leveraging epigenetics to marketable ends and shifts to individual responsibility. (shrink)

For now, the best way to select a child's genes is to select a potential child who has those genes, using genetic testing and either selective abortion, sperm and egg donors, or selecting embryos for implantation. Some people even wish to select against genes that are only mildly undesirable, or to select for superior genes. I call this selection drift– the standard for acceptable children is creeping upwards. The President's Council on Bioethics and others have raised the parental love (...) objection: Just as we should love existing children unconditionally, so we should unconditionally accept whatever child we get in the natural course of things. If we set conditions on which child we get, we are setting conditions on our love for whatever child we get. Although this objection was prompted by selection drift, it also seems to cover selecting against genes for severe impairments. I argue that selection drift is not inconsistent with the ideal of unconditional parental love and, moreover, that the latter actually implies that we should practise selection drift – in other words, we should try to select potential children with the best genetic endowments. My endowment argument for the second claim works from an analogy between arranging an endowment prior to conception to fund a future child's education, and arranging a genetic endowment by selecting a potential child who already has it, where in both cases the child would not have existed without the endowment. I conclude with some programmatic remarks about the nonidentity problem. (shrink)

Photo ID 71252867© Stepan Popov| Dreamstime.com Abstract While Medical Assistance in Dying (MAiD) has been legalized in Canada since 2016, it still excludes eligibility for persons who have mental illness as a sole underlying medical condition. This temporary exclusion was set to expire on March 17th, 2024, but was set 3 years further back by the Government of Canada to March 17th, 2027. This paper presents a critical appraisal of the case of MAiD for individuals with mental illness as the (...) sole underlying medical condition through the analysis of three ethical theories: principlism, deontology, and utilitarianism. Through evidence and discussion, it will be demonstrated that MAiD, in this context, may be ethically justifiable on the grounds of upholding human rights, protecting dignity, and minimizing suffering. Introduction In June of 2016, Medical Assistance in Dying (MAiD) was legalized in Canada.[1] Throughout the first six years, a temporary exclusion of eligibility for persons suffering solely from mental illness was extended.[2] The exclusion of mental illness as a sole underlying medical condition was set to expire on March 17, 2024.[3] However, on February 1, 2024, just over a month before the set expiration, the Government of Canada once again extended the exclusion, this time setting it back three years to March 17, 2027. There are currently several countries that allow MAiD for mental illness, including Belgium, the Netherlands, and Luxembourg.[4] Some countries, like Spain,[5] do not give specific guidance, leaving the matter under discussion by ethicists and courts. In these countries, there are specific (although different) requirements for the process; overall, for mental illness, the illness must be verifiable and not simply related to a perception of satisfaction with the length of life. This extension ignited discussion on whether MAiD for persons who have mental illness as a sole underlying medical condition in Canada is ethically acceptable. As a complex, multi-faceted, and interdisciplinary issue, ethicists assessing MAiD must take into account various moral obligations and considerations. This paper analyses MAiD in this context through the application of three ethical theories: principlism, deontology, and utilitarianism. This paper concludes that, based on the current evidence and knowledge of this developing situation, MAiD for persons with mental illness in Canada may be ethically justified on the grounds of upholding human rights, labour obligations, and dignity. Through the exploration of research and discussions, it will be demonstrated that society at large ought to protect liberty and act towards relieving suffering, thereby supporting the potential eligibility of MAiD for persons who have mental illness. Principlism: The Capacity and Ability to Assess and Decide for One’s Own Life Principlism is the application of four principles: autonomy, beneficence, non-maleficence, and justice. Principlism supports permitting MAiD for mental illness due to the importance of autonomy in decision-making, equitable and just practices for MAiD assessors, and reducing suffering for patients and their family member(s) and/or friend(s). Carter v. Canada, the Canadian Supreme Court ruling of 2015—which changed Canadian law to allow for MAiD—held that the prohibition of MAiD infringed on Canadians’ right to “life, liberty, and the security of the person.” In a unanimous decision, the Supreme Court of Canada decided that the criminal prohibition of MAiD violates the Canadian Charter of Rights and Freedoms.[6] The Court concluded that the criminal law prohibiting MAiD interfered with people’s autonomy and dignity, which are protected by the rights of liberty and security of the person.[7] The ruling emphasized that Canada’s constitution reflects the fundamental importance of individual autonomy in personal decision-making. Research provides evidence that MAiD improves autonomy: A study among psychiatric patients found that 8 of 48 psychiatric patients said the mere option of accessing MAiD was enough to assess their future options for living wholly.[8] These findings complement a study entailing interviews with 30 adults who have mental illness, which emphasized that the ability to access MAiD allows individuals to analyze their quality of life, envision their desired future, and make decisions accordingly.[9] Although not all participants agreed that mental illness as the only underlying medical condition was appropriate for MAiD eligibility, many participants agreed that patient autonomy in decision-making was paramount and should be respected. However, autonomy as an ethical principle does not immediately grant all persons with mental illness the option to access MAiD. There are multiple eligibility criteria for those who wish to receive MAiD, which still must be approved and assessed. Currently, eligibility criteria for MAiD states that individuals must “give informed consent to receive MAiD, meaning that the person has consented to receiving MAiD after they have received all information needed to make this decision.”[10] Consent requires capability or capacity, which is the ability to understand relevant information, appreciate its potential consequences, and make an informed decision for oneself.[11] Like for many other diseases, disabilities, and conditions, patient capability is determined on a case-by-case basis.[12] Given the stigma surrounding those struggling with mental health, this thorough case-by-case examination of an individual patient’s capability and capacity without prejudice or partiality should lead to equitable and fair treatment. Without appropriate testing, those with mental illness could be wrongly stripped of their decision-making power. Arguments against MAiD for those with mental illness have raised concerns about the potential for individuals to harm themselves and others. A survey of MAiD providers demonstrated that physicians believed that the bereavement experience following MAiD is challenging and profoundly distinct and that bereavement support for all members involved should be required.[13] However, while watching one die (of MAiD) may cause harm to their families, friends, and support system at large, it is also important to recognize that watching someone suffer and struggle through their mental health journey also poses significant harm. Qualitative studies in Ontario, Canada, have interviewed family members of persons with mental illness as a sole medical condition, and interviewees shared that witnessing the illness and its impacts on their close one's lives was a very difficult experience.[14] As it relates to MAiD, participants emphasized that those living with mental illness are in the best position to understand their own pain and suffering and, in turn, make their own decisions about relief.[15] In an interview, a MAiD provider stated that MAiD may provide less suffering and more peace, and that, although it “depends on the family,... usually the family is more prepared and at peace.”[16] On the contrary, a person who has mental illness may perceive choosing MAiD as beneficial to their family member(s) and/or friend(s). Among those who died by MAiD in 2021, 35.7 percent reported that they perceived themselves as a burden on their family and friends.[17] While some authors report their concerns regarding such social burden as a potential driving factor for MAiD requests, others report that there are other additional burdens associated with requesting MAiD that may be financial, societal, and personal.[18] As such, the extension of MAiD eligibility to those with mental illness will likely only allow a small number of people to be granted MAiD.[19] Many others will be diverted to appropriate services and treatments. Patients’ decision to choose MAID noted their ability to make choices about their own care, reflecting the value of autonomy.[20] Although it is difficult to determine what is good for families in individual cases, MAiD presents an option that is both beneficent and non-maleficent. Therefore, these arguments satisfy the principles which do not necessarily conflict with MAiD. Deontology: The Duty to Recognize Vulnerability and Relieve Suffering The argument here begins with the fundamental focus of deontology—that moral duty lies in an action rather than in its consequences. Further discussion is required to analyze the impact of MAiD on healthcare workers. The Canadian Medical Association (CMA) Code of Ethics and Professionalism requires physicians to abide by virtues, commitments, and responsibilities in delivering health care and service.[21] The code states that “a compassionate physician recognizes suffering and vulnerability, … and alleviate[s] the patient’s suffering.”[22] In the context of MAiD for persons with mental illness as a sole underlying medical condition, vulnerabilities could be wide in range. Many Canadians are concerned with the interaction between mental health and other social determinants of health, such as the lack of medical, disability, financial, housing, and social support and resources.[23] As a result, another layer to the ethical issue arises: Does permitting MAiD for mental illness treat the symptoms of the issue rather than the root problem itself (social, economic, and systemic inequities)? Some argue against MAiD, stating that the nation should first focus on developing better quality care and service.[24] Others support MAiD as a potential harm reduction approach, given that most of these unjust conditions require a higher level of long-term structural and public policy overhaul.[25] The CMA Code also calls upon physicians to recognize and alleviate patients’ suffering. Some argue that while physicians and medical professionals do work to relieve suffering, they are trained to do so through a primary care-based diagnose-and-treat approach.[26] Studies that have captured Canadian physicians’ experiences providing MAiD report that, although physicians stated that the work was rewarding, it came with many challenges, including strained relationships with coworkers, increased workload, and inadequate compensation.[27] Physicians report that a part of the problem is that MAiD rules are written by lawyers and experts who are removed from its reality in medical practice. As a result, there is a lack of clarity surrounding practice norms and a lack of support for physicians.[28] Thus, while healthcare practitioners have a duty to relieve patients’ suffering, they should feel adequately trained and supported in doing so. If physicians and healthcare professionals recognize vulnerability and relieve suffering, then they should act accordingly, regardless of potential associations or outcomes. Making persons with mental illness eligible for MAiD ensures that treatment to relieve their suffering is available. However, it is imperative that there are sufficient resources and support available to healthcare professionals to ensure that they feel prepared and supported to provide MAiD, should they wish to do so. Utilitarianism: Minimizing Intolerable Suffering and Dying with Dignity Overall, utilitarianism is largely concerned with the greatest happiness principle—to increase the amount of happiness for the greatest number of people. So far, this paper has analyzed individual, family, and practitioner-based ethical considerations. But if MAiD were to be extended to those with mental illness as a singular underlying medical condition, what implications would this have for the world and society at large? There is a global drive toward authorizing organized ending of life, with an increasing number of countries legalizing MAiD.[29] The medical system is generally seen as a safe and appropriate system to carry out MAiD, especially when suicide and self-harm are regarded as “alternatives.” Yet despite these worldwide efforts, many argue through the theory of utilitarianism that the inability to see long-term consequences renders MAiD a premature solution, particularly for those who are unable or unwilling to seek other forms of potentially healing treatment or for those who may undergo MAiD only for a technological innovation or biomedical advancement to later come along as a potential cure.[30] While it is true that MAiD does not prevent these “premature deaths,” it is also true that it does not claim to.[31] MAiD provides an option to alleviate intolerable suffering. Some individuals with severe mental illness do describe their condition as intolerable suffering. MAiD is seen as an option to minimize suffering. It can also be seen as a way to die with dignity and relief.[32] While predicting outcomes is difficult, extending MAiD eligibility for persons experiencing mental illness does not undermine its ability to end suffering. It allows eligible individuals to take charge of their health, their life, and their future. Conclusion Based on the current evidence, allowing MAiD for persons with mental illness as their sole underlying medical condition presents as an ethically justifiable action. The right to self-determination and fair accessibility demonstrates that there is more harm done by prohibiting MAiD for mental illness than allowing it. Such liberty is a right, and in the context of relieving suffering, it is a duty that healthcare workers must uphold, although the ability to opt out of providing MAiD is well established. Thus, to recognize vulnerability and relieve suffering means to provide methods, such as MAiD, for those deeply impacted by mental illness. These justifications stand at both the individual level and for society at large. Nevertheless, it remains imperative to take an upstream approach that addresses the social determinants of health and aims to prevent mental illness and promote long-term, beneficial social change for those suffering, struggling, and vulnerable in our communities. - [1] Jaro Kotalik and David W. Shannon, Medical Assistance in Dying (MAID) in Canada Key Multidisciplinary Perspectives, 1st ed. 2023., The International Library of Bioethics, 104 (Cham: Springer International Publishing, 2023), https://doi.org/10.1007/978-3-031-30002-8. [2] Department of Justice Government of Canada, “Canada’s Medical Assistance in Dying (MAID) Law,” February 21, 2024, https://www.justice.gc.ca/eng/cj-jp/ad-am/bk-di.html. [3] Health Canada, “Final Report of the Expert Panel on MAiD and Mental Illness,” transparency - other, May 13, 2022, https://www.canada.ca/en/health-canada/corporate/about-health-canada/public-engagement/external-advi sory-bodies/expert-panel-maid-mental-illness/final-report-expert-panel-maid-mental-illness.html. [4] Federal Public Service (FPS) Health Belgium, “Federal Commission for the Control and Evaluation of Euthanasia,” n.d., https://consultativebodies.health.belgium.be/en/advisory-and-consultative-bodies/federal-commission- control-and-evaluation-euthanasia.; Government of Netherlands, “Is Euthanasia Allowed in the Netherlands?,” n.d., https://www.government.nl/topics/euthanasia/is-euthanasia-allowed.; “Information on Requesting Euthanasia or Assisted Suicide,” n.d., https://guichet.public.lu/en/citoyens/sante/fin-vie/euthanasie/euthanasie-assistance-suicide.html. [5] Luis Espericueta, First official report on euthanasia in Spain: A comparison with the Canadian and New Zealand experiences, Medicina Clínica (English Edition), Volume 161, Issue 10, 2023, Pages 445-447, ISSN 2387-0206, https://doi.org/10.1016/j.medcle.2023.06.021. [6] Government of Canada, “The Canadian Charter of Rights and Freedoms,” March 15, 2021, https://www.justice.gc.ca/eng/csj-sjc/rfc-dlc/ccrf-ccdl/. [7] Supreme Court of Canada, “Carter v. Canada,” Constitutional Law, 2015, https://scc-csc.lexum.com/scc-csc/scc-csc/en/item/14637/index.do.; Kotalik and Shannon, Medical Assistance in Dying (MAID) in Canada Key Multidisciplinary Perspectives. [8] Karandeep Sonu Gaind, “What Does ‘Irremediability’ in Mental Illness Mean?,” Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie 65, no. 9 (September 2020): 604–6, https://doi.org/10.1177/0706743720928656; Lieve Thienpont et al., “Euthanasia Requests, Procedures and Outcomes for 100 Belgian Patients Suffering from Psychiatric Disorders: A Retrospective, Descriptive Study,” BMJ Open 5, no. 7 (July 27, 2015): e007454, https://doi.org/10.1136/bmjopen-2014-007454. [9] Hamer Bastidas-Bilbao et al., “Walking Alongside: Views of Family Members on Medical Assistance in Dying for Mental Illness as the Sole Underlying Medical Condition,” Qualitative Health Research 33 (September 29, 2023), https://doi.org/10.1177/10497323231197365. [10] Government of Canada, “Canada’s Medical Assistance in Dying (MAID) Law.” [11] Commission sur les soins de fin de vie, “Les conditions de l’admissibilité à l’aide médicale à mourir au Québec: la constance dans l’évolution de la loi concernant les soins de fin de vie,” June 9, 2023, https://csfv.gouv.qc.ca/ fileadmin/docs/autres_rapports/csfv_lcsfv_conditions_ amm_2023-06-29.pdf.; Trudo Lemmens, “When Death Becomes Therapy: Canada’s Troubling Normalization of Health Care Provider Ending of Life,” The American Journal of Bioethics 23, no. 11 (November 2, 2023): 79–84, https://doi.org/10.1080/15265161.2023.2265265. [12] Justine Dembo, Udo Schuklenk, and Jonathan Reggler, “‘For Their Own Good’: A Response to Popular Arguments Against Permitting Medical Assistance in Dying (MAID) Where Mental Illness Is the Sole Underlying Condition,” Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie 63, no. 7 (July 2018): 451–56, https://doi.org/10.1177/0706743718766055. [13] Konia Trouton et al., “Attitudes and Expectations Regarding Bereavement Support for Patients, Family Members, and Friends: Findings from a Survey of MAID Providers,” British Columbia Medical Journal 62, no. 1 (2020). [14] Bastidas-Bilbao et al., “Walking Alongside.” [15] Bastidas-Bilbao et al. [16] Trouton et al., “Attitudes and Expectations Regarding Bereavement Support for Patients, Family Members, and Friends: Findings from a Survey of MAID Providers,” 2020. [17] Ramona Coelho et al., “The Realities of Medical Assistance in Dying in Canada,” Palliative & Supportive Care 21, no. 5 (October 2023): 871–78, https://doi.org/10.1017/S1478951523001025; Health Canada, “Third Annual Report on Medical Assistance in Dying in Canada 2021,” report on plans and priorities;transparency - other, July 26, 2022, https://www.canada.ca/en/health-canada/services/publications/health-system-services/annual-report-me dical-assistance-dying-2021.html; Lemmens, “When Death Becomes Therapy.” [18] Coelho et al., “The Realities of Medical Assistance in Dying in Canada,” October 2023.; Bastidas-Bilbao et al., “Walking Alongside.” [19] Olivia Stefanovich, “Opposition Parties Call for Indefinite Pause to MAID Expansion for Mental Illness | CBC News,” Canadian Broadcasting Corporation, January 28, 2024, https://www.cbc.ca/news/politics/special-joint-committee-maid-mental-illness-report-1.7095679; Benjamin Lopez Steven, “Number of Assisted Deaths Jumped More than 30 per Cent in 2022, Report Says | CBC News,” Canadian Broadcasting Corporation, October 27, 2023, https://www.cbc.ca/news/politics/maid-canada-report-2022-1.7009704. [20] Hamer Bastidas-Bilbao et al., “Searching for Relief from Suffering: A Patient-Oriented Qualitative Study on Medical Assistance in Dying for Mental Illness as the Sole Underlying Medical Condition,” Social Science & Medicine 331 (August 1, 2023): 116075, https://doi.org/10.1016/j.socscimed.2023.116075. [21] Canadian Medical Association, “Canadian Medical Association Code of Ethics and Professionalism” (Canada: Canadian Medical Association, December 8, 2018), https://policybase.cma.ca/link/policy13937. [22] Canadian Medical Association. [23] Coelho et al., “The Realities of Medical Assistance in Dying in Canada,” October 2023; Stefanovich, “Opposition Parties Call for Indefinite Pause to MAID Expansion for Mental Illness | CBC News.” [24] John Paul Tasker, “Liberal Government Promoting a ‘culture of Death’ with Medical Assistance in Dying Law, Conservative MP Says | CBC News,” Canadian Broadcasting Corporation, March 6, 2023, https://www.cbc.ca/news/politics/culture-of-death-medical-assistance-in-dying-mental-illness-1.67695 04. [25] Coelho et al., “The Realities of Medical Assistance in Dying in Canada,” October 2023; Kayla Wiebe and Amy Mullin, “Choosing Death in Unjust Conditions: Hope, Autonomy and Harm Reduction,” Journal of Medical Ethics, April 26, 2023, https://doi.org/10.1136/jme-2022-108871. [26] Ramona Coelho et al., “The Realities of Medical Assistance in Dying in Canada,” Palliative & Supportive Care 21, no. 5 (October 2023): 871–78, https://doi.org/10.1017/S1478951523001025. [27] Konia Trouton et al., “Attitudes and Expectations Regarding Bereavement Support for Patients, Family Members, and Friends: Findings from a Survey of MAID Providers,” British Columbia Medical Journal 62, no. 1 (2020), https://bcmj.org/articles/attitudes-and-expectations-regarding-bereavement-support-patients-family-m embers-and.; William Robert Nielsen, “MAiD in Canada: Ethical Considerations in Medical Assistance in Dying,” Canadian Journal of Bioethics 4, no. 2 (December 9, 2021): 93–98, https://doi.org/10.7202/1084456ar. [28] Coelho et al., “The Realities of Medical Assistance in Dying in Canada,” October 2023. [29] Lemmens, “When Death Becomes Therapy.” [30] William Robert Nielsen, “MAiD in Canada: Ethical Considerations in Medical Assistance in Dying,” Canadian Journal of Bioethics 4, no. 2 (December 1, 2021): 93–98, https://doi.org/10.7202/1084456ar. [31] Steven, “Number of Assisted Deaths Jumped More than 30 per Cent in 2022, Report Says | CBC News.” [32] A. Plaisance et al., “Quebec Population Highly Supportive of Extending Medical Aid in Dying to Incapacitated Persons and People Suffering Only from a Mental Illness: Content Analysis of Attitudes and Representations,” Ethics, Medicine and Public Health 21 (April 1, 2022): 100759, https://doi.org/10.1016/j.jemep.2022.100759. (shrink)

Lawrence Powers advocates a one-fallacy theory in which the only real fallacies are fallacies of ambiguity. He defines a fallacy, in general, as a bad argument that appears good. He claims that the only legitimate way that an argument can appear valid, while being invalid, is when the invalid inference is covered by an ambiguity. Several different kinds of counterexamples have been offered from begging the question, to various forms of ad hominem fallacies. In this paper, I outline (...) three potential counterexamples to Powers' theory, including one that has been addressed already by Powers, and two which are well known problems, but until now have never been applied as counterexamples to Powers' theory. I argue that there is a simpler explanation of these 'hard' cases than positing ambiguities that are not obviously there. (shrink)

The argument from potential has been hard to assess because the versions presented by friends and those presented by enemies have born very little resemblance to each other. I here try to improve this situation by attempting to bring both versions into enforced contact. To this end, I sketch a more detailed analysis of the modern concept of potential than any hitherto attempted. As one would expect, arguments from potential couched in terms of that notion are (...) evident non-starters. I then ask how the modern notion of potential needs to be supplemented in order to produce a more convincing argument. I then enquire whether the supplementations utilised in the most distinguished recent presentations of the argument have anything better than an ad hoc role to play in contemporary metaphysics. I conclude that the rehabilitation of the argument is unlikely; in any event, the onus of proof seems to be on the friend of that argument to show that it is uncontrived. Finally, I argue that the (modern) notion of potential has an important role to play in any plausible account of foetal value. (shrink)

ABSTRACT Consideration of the potentiality of human embryos to develop characteristics of personhood, such as intellect and will, has figured prominently in arguments against abortion and the use of human embryos for research. In particular, such consideration was the basis for the call of the US President's Council on Bioethics for a moratorium on stem cell research on human embryos. In this paper, I critique the concept of potentiality invoked by the Council and offer an alternative account. In contrast to (...) the Council's view that an embryo's potentiality is determined by definition and is not affected by external conditions that may prevent certain possibilities from ever being realized, I propose an empirically grounded account of potentiality that involves an assessment of the physical and decisional conditions that may restrict an embryo's possibilities. In my view, some human embryos lack the potentiality to become a person that other human embryos have. Assuming for the sake of argument that the potential to become a person gives a being special moral status, it follows that some human embryos lack this status. This argument is then used to support Gene Outka's suggestion that it is morally permissible to experiment on ‘spare’ frozen embryos that are destined to be destroyed. (shrink)

Thomas Aquinas describes embryological development as a succession of vital principles, souls, or substantial forms of which the last places the developing being in its own species. In the case of human beings this form is the rational soul. Aquinas' well-known commitment to the view that there is only one substantial form for each composite and that a substantial form directly informs prime matter leads to the conclusion that the succession of soul kinds is non-cumulative. The problem is that this (...) view seems to entail discontinuity in the process of generation. Aquinas argues for the continuity of a conceived being by appealing to the teleological argument at the core of Aristotle's embryogenesis theory: according to Aristotle, embryonic development is a gradual actualization of the form of the species, potentially present in the embryo from the outset. Aquinas denies such a gradualist account due to his metaphysical commitments , arguing instead that the .. (shrink)

Jeff McMahan has recently provided a forceful defense of methodological anti-speciesism against speciesists’ claim that species standard is a meaningful criterion to assess the value of lives and the nature of deprivation. In this paper I discuss McMahan’s favored account (the Intrinsic Potential Account) to assess the value of life and the nature of deprivation and challenge its overall ethical and methodological tenability. I level three charges against the Intrinsic Potential Account. I argue, first, that it cannot be (...) consistent with some widely held egalitarian moral intuitions. Second, it is unconvincing in its justification of the idea of equal respect for persons. Third, it is unclear how it can make sense of the value of individual capacities without referring to some species-based standard. Although I remain neutral with respect to the debate between anti-speciesists and speciesists, I argue that anti-speciesists cannot rely on McMahan’s arguments. (shrink)

In his book Engineered Death: Abortion, Suicide, Euthanasia and Senecide, John Woods uses an argument from analogy to establish the following conclusion: even if one grants that foetuses are not persons but only potential persons, killing foetuses is murder. Murder, according to Woods, is the defeasibly wrongful violation of the right to life ascribed to persons. If this argument is successful, it would of course have profound consequences for the ongoing philosophical debate over the morality of abortion. (...) Whether or not they hold that foetuses are persons, philosophers would be forced to adopt the same moral attitude toward foeticide as they would adopt toward the killing of persons. That is, the killing of foetuses and the killing of persons would be defeasibly wrong in the same way; their wrongfulness could be defeated only in special and limited circumstances, perhaps like those suggested by Judith Thomson in her “Defense of Abortion”. (shrink)

I argue that categorical realism, contrary to what most believe today, holds for quantum (and indeed for all) objects and substances. The main argument consists of two steps: (i) the recent experimental verification of the AB effect gives strong empirical evidence for taking quantum potentials as physically real (or substantival), which suggests a change of the data upon which any viable interpretation of quantum theory must rely, and (ii) quantum potentials may be consistently taken as the categorical properties of (...) quantum objects so that categorical realism can be restored. (shrink)

Can we conceive cogently of all knowledge – in particular, all knowledge of truths – as being knowledge-how? This paper provides reasons for thinking not only that is this possible, but that it is conceptually advantageous and suggestive. Those reasons include adaptations of, and responses to, some classic philosophical arguments and ideas, from Descartes, Hume, Peirce, Mill, and Ryle. The paper’s position is thus a practicalism – a kind of pragmatism – about the nature of knowledge, arguing that all knowledge (...) is knowledge-how to act – to do this, to do that. Such a conception can include, too, a distinctive view of the metaphysical relation between knowledge and belief. We see that, contrary to what most contemporary epistemologists say, knowledge need not be a form of belief. Instead, a belief that p can be a way simply of enriching or strengthening knowledge that p. It can do this in a paracticalist way, by allowing one to do more with the knowledge. (shrink)

The possibility of human reproductive cloning has led some bioethicists to suggest that potentiality-based arguments for fetal moral status become untenable, as such arguments would be committed to making the implausible claim that any adult somatic cell is itself a potential person. In this article I defend potentiality-based arguments for fetal moral status against such a reductio. Starling from the widely-held claim that the maintenance of numerical identity throughout successive changes places constraints on what a given entity can plausibly (...) be said to have the potential to become, I argue that the cell reprogramming that takes place in reproductive cloning is such that it produces a new individual, and so adult somatic cells cannot be potential persons. (shrink)

There's a student in my philosophy class who has "real potential." I might express this thought in any of the following ways: "She is potentially a philosopher"; "She is a potential philosopher"; "She has the potential to be a philosopher." The first way uses a cognate of "potential" as an adverb to modify "is." The second ways uses "potential" as an adjective to modify "philosopher." However, the third way uses "potential" as a noun to (...) refer to something that the student has. What kind of thing is this potential? One worry about even asking this question is that this nominalization of the adjective "potential" suggests a metaphysical picture that is an artifact of language. This is even more strongly suggested by the less ambiguous nominalization "potentiality." Once we have the term "potentiality," we have a new kind of entity to countenance, and questions about its nature arise. One might argue, just because we use the word "potentiality," we should not think that it refers to a "thing" that someone can "have." There is something disingenuous about such an argument. It proceeds as if the adverbial and adjectival uses of "potential" are unproblematic, and questions only arise with the nominalization. But it is not obvious what it means to potentially be something, or what it means to be a potential something. To say that someone "is potentially" a philosopher is to talk about a way of being that falls short of actuality. And a "potential philosopher" is not a kind of philosopher at all. So what is it? Each of the three above formulations is a modal claim. If there is anything philosophical puzzling about a potentiality claim, it is not going to go away by translating it into an equivalent modal claim. In this chapter I defend the existence of potentialities against anti-realist arguments, and make a proposal as to their nature. The proposal, in short, is that potentialities are properties, specifically dispositions, though more needs to be said about properties and dispositions. I will do this in Part I. In Part II, I will address two lines of argument against potentialities: that they are reducible, and that they are causally inert. (shrink)

Do actual infinities exist or are they impossible? Does mathematical practice require the existence of actual infinities, or are potential infinities enough? Contrasting points of view are examined in depth, concentrating on Aristotle’s ancient arguments against actual infinities. In the long 19th century, we consider Cantor’s successful rehabilitation of the actual infinite within his set theory, his views on the continuum, Zeno's paradoxes, and the domain principle, criticisms by Frege, and the axiomatisation of set theory by Zermelo, as well (...) as Zermelo’s assertion of the primacy of potential infinity in mathematics. (shrink)

Recent International Relations scholarship has identified ‘societal multiplicity’ as the ontological concept that gives IR its identity as an academic discipline. My article, by contrast, addresses the question: What are the consequences, that is, the positive potential and the necessary costs, of understanding multiplicity as a moral-political value in world politics? The question is important because, in contrast to the focus on multiplicity as the ontology of IR, it allows us to develop a more radically democratic idea of multiplicity (...) as a value in world politics. To address this question, I will bring Rosenberg’s conception of societal multiplicity into conversation with the radically democratic idea of Tully’s ‘strange multiplicity’ and draw out the consequences of such a normative turn. My argument is that while Rosenberg does not frame multiplicity as a value, Tully’s normative understanding of the concept harbours enormous potential to transform oppressive and dominating practices in world politics. However, I will also show that Tully’s general rejection of all forms of domination comes at a price that must not be underestimated. It is of crucial importance to get a clear picture of these consequences as we must decide whether or not this price is, ultimately, worth paying. (shrink)

This paper examines Aristotle's discussion of the priority of actuality to potentiality in geometry at Metaphysics Θ9, 1051a21–33. Many scholars have assumed what I call the "geometrical construction" interpretation, according to which his point here concerns the relation between an inquirer's thinking and a geometrical figure. In contrast, I defend what I call the "geometrical analysis" interpretation, according to which it concerns the asymmetrical relation between geometrical propositions in which one is proved by means of the other. His argument (...) as so construed is ultimately based on the asymmetrical relation between the corresponding geometrical facts. Then I explore this ontological priority in geometry by drawing attention to a parallel passage, Posterior Analytics II.11, 94a24–35, where Aristotle explains the relation between the same geometrical propositions in connection to material causation. (shrink)

Much of the appeal of deliberative democracy lies in its emancipatory promise to give otherwise disadvantaged groups a voice, and to grant them influence through reasoned argument. However, the precise mechanisms for delivery of this promise remain obscure. After reviewing Habermas's formulation of deliberation, the article draws on recent theories of argumentation to provide a more detailed account of such mechanisms. The article identifies the key emancipatory mechanism as explicitness in language. It outlines the primary modalities of this mechanism: (...) expressing differences of opinion, mobilising a shared standard of inference, and recognising and excluding fallacious appeals to irrelevant factors such as force or authority. It describes how these modalities are enhanced at a secondary, reflexive level that recognises the partiality and defeasibility of particular argumentative exchanges. Such qualifications, it is argued, support a model of deliberation across discourses that allows a clearer appreciation of its potential and limits. (shrink)

To a large extent and one that is highly structuring, energy choices that are made in a society are political choices. This article aims at studying how these choices can be redirected by technological developments associated with renewable energy, thus contributing to a redistribution of opportunities and correspondingly to social reorganizations. In order to show that the development of alternative energies not only depends on technological advances but can also, in the process, reveal political potentialities, three steps are proposed. The (...) first step will clarify the theoretical arguments in favor of an approach in terms of “technological potentialism.” Second, we will extend this approach by identifying a set of potentialities linked with renewable energies and the model that could arise from these alternative forms or approaches. Finally, we will examine how these potentialities could find paths to become effective. (shrink)

The purpose of this paper is to examine how the shifting conceptualization of the democratizing potential of digital technology can be more comprehensively understood by bringing in science and technology studies (STS) perspectives to communication scholarship. The synthesis and discussion are aiming at providing an interdisciplinary theoretical framework for comprehensively understand the democratizing potential of digital technology, and urging researchers to be conscious of assumptions underpinning epistemological positions they take when examining the issue of democratizing potential of (...) digital technology.,The paper is a constructive literature review that synthesizes and integrates existed literature from communication and STS on the democratizing potential of digital technology. The author attempts to bridge theoretical perspectives from communication and STS by identifying core arguments and debates around key concepts and discussing potential implications of different epistemological positions.,Tracing the evolving analytical perspectives of technological determinism, the social construction of technology and actor-network theory, the author argues that researchers should be aware of their underlying epistemological assumptions embedded in relationships among users, technological systems and social factors. Analyzing the contested notion of power in the democratizing potential of digital technology from two contrasting perspectives, the author argues that researchers should recognize both the front end and the back end of digital technology in their analysis. In addition, new challenges of algorithm opacity and accountability in impacting the democratizing potential of digital technology are further discussed.,This study provides an original interdisciplinary theoretical framework by reviewing and bridging scholarship from communication and STS in examining the democratizing potential of digital technology. Adopting this interdisciplinary theoretical framework helps researchers develop a more nuanced and comprehensive understanding of the democratizing potential of digital technology. (shrink)

ABSTRACT: A popular response to proponents of embryonic stem cell research and advocates of abortion rights alike-summarized by claims such as “you came from an embryo!” or “you were a fetus once!”-enjoys a rich philosophical pedigree in the arguments of Hare, Marquis, and others. According to such arguments from potentiality, the prenatal human organism is morally valuable because every person’s biological history depends on having completed embryonic and fetal stages. In this article I set out the steps of the underlying (...) argument in light of how it has been cast in the philosophical literature and uncover an intriguingly illicit inference.RÉSUMÉ: On répond souvent aux avocats de la recherche sur les cellules souches et à ceux du droit a l’avortement par une argumentation qui se résume à des affirmations comme : «vous provenez d’un embryon!» ou «vous avez déjà été un fœtus!» -- ce genre de réponse appartient à une riche lignée philosophique qui inclut les arguments de Hare, Marquis et d’autres encore. Selon ces arguments fondés sur la potentialité, l’organisme humain prénatal possède une valeur morale parce que l’histoire biologique de chaque personne dépend de l’accomplissement des états embryonnaire et fœtal. Je présente ici les étapes du raisonnement qui se trouve au fondement de cette argumentation telle qu’elle est formulée dans la littérature philosophique. J’y découvre une inférence curieusement invalide. (shrink)

Placed between constituting and constituted power, homo sacer reveals the state of exception, which through sovereign ban, is kept both inside and outside the law. Agamben’s latest political and legal philosophy is based upon this concept. As the victim of sovereignty, homo sacer unfolds the paradox of sovereign power, criticiz- ing its fundaments and showing the emptiness of law. However, for potentiality which is at the centre of Agamben’s argument, we need to look not only outside sovereignty and sovereign (...) power, but also outside homo sacer. This ar- ticle aims to examine such space, arguing that through absolute potentiality, the fulfilment of law is possible with the content to be focused on reaching conditions of justice and happy life. (shrink)

In Aristotle’s writings regarding the biology of embryology, especially in the Generation of Animals, he contends that the mother’s menstrual fluids provide the material for the generation of the offspring, and the father’s form determines its formation as a member of that species (e.g. human). The katamenia (menstrual fluids) of the mother are said to be potentially all the body parts of the offspring, though actually none of them. So, the fluids are potentially the offspring. But are they a first (...) potentiality or second potentiality (first actuality) of a human, in the terminology of De Anima II? In this paper I will argue that katamenia are a first potentiality of a human. My first argument is that katamenia do not have the potential for human activities such as thinking, but rather the potential of becoming something having the potential for those activities. I answer the objection that katamenia are not even a first potentiality, by appealing to an important text contending that for any x whose source of becoming is external, x is potentially y if nothing in x with respect to matter needs to be changed in order for an external principle to make x into y. (shrink)

The thesis that every truth is knowable is usually glossed by decomposing knowability into possibility and knowledge. Under elementary assumptions about possibility and knowledge, considered as modal operators, the thesis collapses the distinction between truth and knowledge (as shown by the so-called Fitch-argument). We show that there is a more plausible interpretation of knowability—one that does not decompose the notion in the usual way—to which the Fitch-argument does not apply. We call this the potential knowledge-interpretation of knowability. (...) We compare our interpretation with the rephrasal of knowability proposed by Edgington and Rabinowicz and Segerberg, inserting an actuality-operator. This proposal shares some key features with ours but suffers from requiring specific transworld-knowledge. We observe that potential knowledge involves no transworld-knowledge. We describe the logic of potential knowledge by providing models for interpreting the new operator. Finally we show that the knowability thesis can be added to elementary conditions on potential knowledge without collapsing modal distinctions. (shrink)

This article is the first indepth ethical analysis of empirical studies that support the claim that children born without major parts of their cerebral cortex are capable of conscious experiences and have a rudimentary capacity for agency. Congenitally decorticate children have commonly been classified as persistently vegetative, with serious consequences for their well-being and opportunities to flourish. The paper begins with an explication of the rights-based normative framework of the argument, including conceptual analysis of the terms ‘agency’, ‘potentiality for (...) agency’ and ‘gradual approach of agency’. It critically examines Alan Gewirth’s account of the criteria for being a rights bearer and principles for settling rights conflicts between agents and potential agents. It then applies the rights-based normative framework to the ethical challenges associated with care for congenitally decorticate children. It argues that recent empirical studies support the claim that the concepts ‘potential for agency’ and ‘capacity for rudimentary agency’ apply to children who are born without major parts of their cerebral cortex. The article finally discusses important medical ethical implications of these results. It specifically focuses on congenitally decorticate children’s preparatory rights to a stimulating intellectual and social environment. (shrink)

Oxford philosopher Nick Bostrom; in his recent and celebrated book Superintelligence; argues that advanced AI poses a potentially major existential risk to humanity; and that advanced AI development should be heavily regulated and perhaps even restricted to a small set of government-approved researchers. Bostrom’s ideas and arguments are reviewed and explored in detail; and compared with the thinking of three other current thinkers on the nature and implications of AI: Eliezer Yudkowsky of the Machine Intelligence Research Institute ; and David (...) Weinbaum and Viktoras Veitas of the Global Brain Institute. Relevant portions of Yudkowsky’s book Rationality: From AI to Zombies are briefly reviewed; and it is found that nearly all the core ideas of Bostrom’s work appeared previously or concurrently in Yudkowsky’s thinking. However; Yudkowsky often presents these shared ideas in a more plain-spoken and extreme form; making clearer the essence of what is being claimed. For instance; the elitist strain of thinking that one sees in the background in Bostrom is plainly and openly articulated in Yudkowsky; with many of the same practical conclusions. Bostrom and Yudkowsky view intelligent systems through the lens of reinforcement learning – they view them as “reward-maximizers” and worry about what happens when a very powerful and intelligent reward-maximizer is paired with a goal system that gives rewards for achieving foolish goals like tiling the universe with paperclips. Weinbaum and Veitas’s recent paper “Open-Ended Intelligence” presents a starkly alternative perspective on intelligence; viewing it as centered not on reward maximization; but rather on complex self-organization and self-transcending development that occurs in close coupling with a complex environment that is also ongoingly self-organizing; in only partially knowable ways. It is concluded that Bostrom and Yudkowsky’s arguments for existential risk have some logical foundation; but are often presented in an exaggerated way. For instance; formal arguments whose implication is that the “worst case scenarios” for advanced AI development are extremely dire; are often informally discussed as if they demonstrated the likelihood; rather than just the possibility; of highly negative outcomes. And potential dangers of reward-maximizing AI are taken as problems with AI in general; rather than just as problems of the reward-maximization paradigm as an approach to building superintelligence. If one views past; current; and future intelligence as “open-ended;” in the vernacular of Weaver and Veitas; the potential dangers no longer appear to loom so large; and one sees a future that is wide-open; complex and uncertain; just as it has always been. (shrink)

Many families refuse to consent to donation from their deceased relatives or over-rule the consent given before death by the patient, but giving families more information about the potential recipients of organs could reduce refusal rates. In this paper, we analyse arguments for and against doing so, and conclude that this strategy should be attempted. While it would be impractical and possibly unethical to give details of actual potential recipients, generic, realistic information about the people who could benefit (...) from organs should be provided to families before they make a decision about donation or attempt to over-rule it. (shrink)

Human cerebral organoids are three-dimensional biological cultures grown in the laboratory to mimic as closely as possible the cellular composition, structure, and function of the corresponding organ, the brain. For now, cerebral organoids lack blood vessels and other characteristics of the human brain, but are also capable of having coordinated electrical activity. They have been usefully employed for the study of several diseases and the development of the nervous system in unprecedented ways. Research on human cerebral organoids is proceeding at (...) a very fast pace and their complexity is bound to improve. This raises the question of whether cerebral organoids will also be able to develop the unique feature of the human brain, consciousness. If this is the case, some ethical issues would arise. In this article, we discuss the necessary neural correlates and constraints for the emergence of consciousness according to some of the most debated neuroscientific theories. Based on this, we consider what the moral status of a potentially conscious brain organoid might be, in light of ethical and ontological arguments. We conclude by proposing a precautionary principle and some leads for further investigation. In particular, we consider the outcomes of some very recent experiments as entities of a potential new kind. (shrink)

This article approaches the relationship of normative argumentation studies and descriptive persuasion effects research by pointing to several empirical findings that raise questions or puzzles about normatively-proper argumentative conduct. These findings indicate some complications in the analysis of normatively desirable argumentative conduct – including some ways in which practical persuasive success may not be entirely compatible with normatively-desirable advocacy practices.

In this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often‐ugly history of scientific attempts to understand the genetic contributions to human behaviors and social outcomes. They then describe what the current science—including genomewide association studies and polygenic indexes—can and cannot tell us, as well as its risks and potential benefits. They conclude with a discussion of responsible behavior in the context of SBG (...) research. SBG research that compares individuals within a group according to a “sensitive” phenotype requires extra attention to responsible conduct and to responsible communication about the research and its findings. SBG research (1) on sensitive phenotypes that (2) compares two or more groups defined by (a) race, (b) ethnicity, or (c) genetic ancestry (where genetic ancestry could easily be misunderstood as race or ethnicity) requires a compelling justification to be conducted, funded, or published. All authors agree that this justification at least requires a convincing argument that a study's design could yield scientifically valid results; some authors would additionally require the study to have a socially favorable risk‐benefit profile. (shrink)

Located at the crossroads of the Eastern and Western world, Turkey today is characterized by a demographically versatile and modernizing society as well as a rapidly developing economy. Currently, the country is negotiating its accession to the European Union. This article yields some factual grounding into the ongoing value-related debate concerning Turkey's potential EU-membership. It describes a mixed-methodology study on moral reasoning in Austria and Turkey. In this study, the arguments given by individuals when evaluating ethically problematic situations in (...) business were compared. Although there were major consistencies, a number of differences were found. These differences, however, were not in the substance of arguments used but in their relative frequency. Overall, our findings suggest that young, well-educated urban individuals from Western Christian and Eastern Islamic countries are highly consistent in their moral reasoning. (shrink)

I examine the reasons Aristotle presents in Physics VIII 8 for denying a crucial assumption of Zeno’s dichotomy paradox: that every motion is composed of sub-motions. Aristotle claims that a unified motion is divisible into motions only in potentiality (δυνάμει). If it were actually divided at some point, the mobile would need to have arrived at and then have departed from this point, and that would require some interval of rest. Commentators have generally found Aristotle’s reasoning unconvincing. Against David Bostock (...) and Richard Sorabji, inter alia, I argue that Aristotle offers a plausible and internally consistent response to Zeno. I defend Aristotle’s reasoning by using his discussion of what to say about the mobile at boundary instants, transitions between change and rest. There Aristotle articulates what I call the Changes are Open, Rests are Closed Rule: what is true of something at a boundary instant is what is true of it over the time of its rest. By contrast, predications true of something over its period of change are not true of the thing at either of the boundary instants of that change. I argue that this rule issues from Aristotle’s general understanding of change, as laid out in Phys. III. It also fits well with Phys. VI, where Aristotle maintains that there is a first boundary instant included in the time of rest, but not a “first in which the mobile began to change.” I then show how this rule underlies Aristotle’s argument that a continuous motion cannot be composed of actual sub-motions. Aristotle distinguishes potential middles, points passed through en route to a terminus, from actual middles. The Changes are Open, Rests are Closed Rule only applies to actual middles, because only they are boundaries of change that the mobile must arrive at and then depart from. On my reading, Aristotle argues that the instant of arrival, the first instant at which the mobile has come to be at the actual middle, cannot belong to the time of the subsequent motion. If it did, the mobile would already be moving towards the next terminus and thus, per Phys. VI 6, would have already left. But it cannot have moved away from the midpoint at the very same moment it has arrived there. This means that the instant of arrival must be separated from the time of departure by an interval of rest. I show how Aristotle’s reasoning applies generally to rule out any continuous reflexive motion or continuous complex rectilinear motion. On my interpretation, however, the argument does not apply to every change of direction. When, as in the case of projectile motion, multiple movers and their relative powers explain why the mobile changes directions, distinct sub-motions are not involved. Aristotle holds that such motions cannot be continuous, not because they involve intervals of rest, but because they involve multiple causes of motion. My interpretation of the Changes are Open, Rests are Closed Rule allows us to make better sense of Aristotle’s argument than any previous interpretation. (shrink)

This volume deals with approaches to handling contradictory information. These include approaches for actual contradiction - both A and not-A can be proven from the information - and approaches for potential contradiction - where the information may contain arguments for A and arguments for not-A, but the system suppresses the contradiction by, for example, preferring some arguments over others. Approaches covered include paraconsistent logics, modal logics, default logics, conditional logics, defeasible logics and paraconsistent semantics for logic programming. The volume (...) is of interest to students, researchers and practitioners in artificial intelligence, software engineering, logic, language and philosophy. This volume is the first handbook to give a comprehensive coverage of handling contradictory information. (shrink)

This paper deals with Gärdenfors’ theory of conceptual spaces. Let ${\mathcal {S}}$ be a conceptual space consisting of 2-type fuzzy sets equipped with several kinds of metrics. Let a finite set of prototypes $\tilde{P}_1,\ldots,\tilde{P}_n\in \mathcal {S}$ be given. Our main result is the construction of a classification algorithm. That is, given an element ${\tilde{A}}\in \mathcal {S},$ our algorithm classifies it into the conceptual field determined by one of the given prototypes $\tilde{P}_i.$ The construction of our algorithm uses some physical analogies (...) and the Newton potential plays a significant role here. Importantly, the resulting conceptual fields are not convex in the Euclidean sense, which we believe is a reasonable departure from the assumptions of Gardenfors’ original definition of the conceptual space. A partitioning algorithm of the space $\mathcal {S}$ is also considered in the paper. In the application section, we test our classification algorithm on real data and obtain very satisfactory results. Moreover, the example we consider is another argument against requiring convexity of conceptual fields. (shrink)

In Aristotle’s writings regarding the biology of embryology, especially in the Generation of Animals, he contends that the mother’s menstrual fluids provide the material for the generation of the offspring, and the father’s form determines its formation as a member of that species (e.g. human). The katamenia (menstrual fluids) of the mother are said to be potentially all the body parts of the offspring, though actually none of them. So, the fluids are potentially the offspring. But are they a first (...) potentiality or second potentiality (first actuality) of a human, in the terminology of De Anima II? In this paper I will argue that katamenia are a first potentiality of a human. My first argument is that katamenia do not have the potential for human activities such as thinking, but rather the potential of becoming something having the potential for those activities. I answer the objection that katamenia are not even a first potentiality, by appealing to an important text contending that for any x whose source of becoming is external, x is potentially y if nothing in x with respect to matter needs to be changed in order for an external principle to make x into y. Keywords: Aristotle, katamenia, potentiality, actuality, Generation of Animals. (shrink)

This article adopts the framework set out in ‘Associative Political Obligations’ to ask two further questions about the theory of associative political obligation. (i) Which of the different interpretations of the theory of associative political obligation is most plausible? And (ii) what would be the implications of such a view? It is argued that (i) the most attractive version of the argument is one according to which such obligations obtain only in morally acceptable communities, and only between what may (...) be called ‘thick’ members. And (ii) that such a theory should give up on at least some of the conclusions that associativist theorists have tried to defend, such as that associative political obligations can establish the legitimacy of states. However, it is also suggested that this should not be considered a regrettable retreat. (shrink)

Aldehyde dehydrogenase 2 (ALDH2) deficiency constitutes one of the most common hereditary enzyme deficiencies, affecting 35% to 40% of East Asians and 8% of the world population. It causes the well-known Asian Alcohol Flush Syndrome, characterized by facial flushing, palpitation, tachycardia, nausea, and other unpleasant feelings when alcohol is consumed. It is also associated with a marked increase in the risk of a variety of serious disorders, including esophageal cancer and osteoporosis. Our recent studies with murine models have demonstrated that (...) a one-time administration of an adeno-associated virus (AAV) gene transfer vector expressing the human ALDH2 coding sequence (AAVrh.10hALDH2) will correct the deficiency state and prevent alcohol-induced abnormalities of the esophagus and bone. If successful in humans, such strategy would reduce the increased risk-associated disorders such as esophageal cancer and osteoporosis, but also prevent the Asian Alcohol Flush Syndrome. This treatment thus raises ethical concerns: although it would potentially prevent fatal disease, it could also allow affected individuals to drink alcohol without suffering the Asian Alcohol Flush Syndrome and, hence, potentially enable personal destructive behavior. Here we explore the ethical arguments against the development of a gene therapy for ALDH2 deficiency and we find them wanting. We contend that development of such treatments is ethically appropriate and should be part and parcel of the solutions offered against the condition. (shrink)

Bilateralists hold that the meanings of the connectives are determined by rules of inference for their use in deductive reasoning with asserted and denied formulas. This paper presents two bilateral connectives comparable to Prior's tonk, for which, unlike for tonk, there are reduction steps for the removal of maximal formulas arising from introducing and eliminating formulas with those connectives as main operators. Adding either of them to bilateral classical logic results in an incoherent system. One way around this problem is (...) to count formulas as maximal that are the conclusion of reductio and major premise of an elimination rule and to require their removability from deductions. The main part of the paper consists in a proof of a normalisation theorem for bilateral logic. The closing sections address philosophical concerns whether the proof provides a satisfactory solution to the problem at hand and confronts bilateralists with the dilemma that a bilateral notion of stability sits uneasily with the core bilateral thesis. (shrink)

This paper considers a formalisation of classical logic using general introduction rules and general elimination rules. It proposes a definition of ‘maximal formula’, ‘segment’ and ‘maximal segment’ suitable to the system, and gives reduction procedures for them. It is then shown that deductions in the system convert into normal form, i.e. deductions that contain neither maximal formulas nor maximal segments, and that deductions in normal form satisfy the subformula property. Tarski’s Rule is treated as a general introduction rule for implication. (...) The general introduction rule for negation has a similar form. Maximal formulas with implication or negation as main operator require reduction procedures of a more intricate kind not present in normalisation for intuitionist logic. (shrink)

This paper proves normalisation theorems for intuitionist and classical negative free logic, without and with the $\invertediota$ operator for definite descriptions. Rules specific to free logic give rise to new kinds of maximal formulas additional to those familiar from standard intuitionist and classical logic. When $\invertediota$ is added it must be ensured that reduction procedures involving replacements of parameters by terms do not introduce new maximal formulas of higher degree than the ones removed. The problem is solved by a rule (...) that permits restricting these terms in the rules for $\forall$, $\exists$ and $\invertediota$ to parameters or constants. A restricted subformula property for deductions in systems without $\invertediota$ is considered. It is improved upon by an alternative formalisation of free logic building on an idea of Ja\'skowski's. In the classical system the rules for $\invertediota$ require treatment known from normalisation for classical logic with $\lor$ or $\exists$. The philosophical significance of the results is also indicated. (shrink)

In this paper, we consider a set of quite interesting three- and four-valued logics and prove the normalisation theorem for their natural deduction formulations. Among the logics in question are the Logic of Paradox, First Degree Entailment, Strong Kleene logic, and some of their implicative extensions, including RM3 and RM3⊃. Also, we present a detailed version of Prawitz’s proof of Nelson’s logic N4 and its extension by intuitionist negation.