This chapter contains sections titled: General Characteristics of the Concept of Natural Life The Path to the Individualization of Matter Chemistry and Individuality: The Appearance and Disappearance of Life Contradiction in Chemicals The Necessary Limits of the Inorganic The Path to the Free Individuality of Life Conclusion References Abbreviations Works Cited.

No one has the right to say what should be done to their body after deathIn my opinion any concept of property in the human body either during life or after death is biologically inaccurate and morally wrong. The body should be regarded as on loan to the individual from the biomass, to which the cadaver will inevitably return. Development of immunosuppressive drugs has resulted in the cadaver becoming a unique and invaluable resource to those who will benefit from (...) organ donation. Faced with the biological reality, the moral error of any concept of property in the body, and the quantitative failure of voluntary organ donation, I believe that the right of control over the cadaver should be vested in the state as representative of those who may benefit from organ donation.How one regards the dead human body, the cadaver, is in part governed by one’s familiarity with it. At the present time, very few people ever see a cadaver which has not in some way been altered after death, and even fewer touch, handle, deal in any way with the dead human body. In developed countries, death itself most frequently occurs away from the home, in an institution, under the supervision of professional caregivers. For most people, ideas concerning the cadaver, its nature, the proper way to deal with it, are formed under these conditions.As a pathologist specialising in forensic pathology, for 50 years I have been at the other end of the spectrum of experience. In my daily work I have been privileged to examine the cadaver in all its stages after death from the immediate postmortem moments through all the stages of decomposition to bare bones. Working in a relatively small community, I have sometimes been charged with examining the body of someone I …. (shrink)

"Hegel’s Philosophical Psychology" draws attention to a largely overlooked piece of Hegel’s philosophy: his substantial and philosophically rich treatment of psychology at the end of the 'Philosophy of Subjective Spirit', which itself belongs to his main work, the "Encyclopaedia of the Philosophical Sciences". This volume makes the case that Hegel’s approach to philosophy of mind as developed within this text can make an important contribution to current discussions about mind and subjectivity, and can help clarify the notion of (...) spirit within Hegel’s larger philosophical project. Scholars from different schools of Hegelian thought provide a multifaceted overview of Hegel’s 'Psychology': Part I begins with an overview of Hegel’s 'Philosophy of Subjective Spirit', which outlines both its historical context and its systematic context within Hegel’s philosophy of subjective spirit. Parts II and III then investigate the individual chapters of the sections on psychology: the theoretical mind and the practical and free mind. The volume concludes by examining the challenges which Hegel’s 'Psychology' poses for contemporary epistemological debates and the philosophy of psychology. Throughout, the volume brings Hegel’s views into dialogue with 20th- and 21st-century thinkers such as Bergson, Bourdieu, Brandom, Chomsky, Davidson, Freud, McDowell, Sellars, Wittgenstein, and Wollheim. (shrink)

. G. W. Leibniz did not contribute directly to scientific discoveries in the life sciences, but he provided several relevant analyses on methods of investigation applicable to complex, and in particular organic, phenomena. Leibniz's theory of organic bodies and his methodological model had deep and broad implications for the development of physiology at the turn of the seventeenth and eighteenth centuries. This paper focuses on a methodological issue which divided natural philosophers and physiologists during the early Enlightenment—about (...) which Leibniz supported original viewpoints which have kept a certain relevance, mutatis mutandis, in later contexts. The issue in question concerns the relation between the surface organization of phenomena and the deeper organization of underlying micro-structures and micro-processes. In a search for the sufficient reason for phenomena, hypothetical models are called upon to provide determining reasons for surface effects. These reasons represent processes involving micro-mechanisms combined so as to account for the emerging organization. (shrink)

Invites the reader to examine the concept of the One in several complex cultural and philosophical mileux. The uniqueness of the study is its collation of Eastern and Western sources and systems.

In everyday discourse we often attribute intentional states to groups. These attributions are found not only in colloquial speech but also in the context of legal, moral, and social scientific research. Contemporary accounts of group intentionality have attempted to analyze these ascriptions in terms of the intentional states of individuals in the group. Although these accounts acknowledge that group intentional ascriptions are something more than mere metaphors, they do not typically acknowledge groups as genuine intentional agents. I challenge these (...) contemporary accounts and individualistic intuitions by arguing that, given a plausible account of the nature of intentionality, certain groups are genuine intentional agents. ;Focusing on the work of Gilbert, Tuomela, Searle, and Bratman, I argue that there are significant explanatory reasons for countenancing groups as legitimate intentional agents, reasons that require that we reject the individualism to which each of these authors is committed. My account of collective intentional agency is grounded in interpretationism. Interpretationism is the view an agent is an intentional agent if and only if he or she is interpretable. I defend interpretationism by building on the work of Davidson and Dennett. In particular, I develop more fully the notion of a rational point of view and argue that an adequate interpretationism must accommodate it. A rational point of view is not simply a point of view from which one's own actions can be seen as intelligible, it is a point of view from which an agent engages in deliberation and it is a locus of authority and responsibility. I argue that organizations have a rational point of view and are, therefore, interpretable. Thus, organizations are genuine intentional agents. ;If groups can be believers, then group knowledge and justification are coherent notions. There is a pervasive individualistic bias in contemporary epistemology, however, that rejects the idea of group knowledge and justification. This bias is largely motivated by the assumption that cognition is a process that takes place only within the individual mind/brain. I challenge this bias by showing how the standard models of individual cognition and epistemic agency can be extended to groups. (shrink)

The machine conception of the organism (MCO) is one of the most pervasive notions in modern biology. However, it has not yet received much attention by philosophers of biology. The MCO has its origins in Cartesian natural philosophy, and it is based on the metaphorical redescription of the organism as a machine. In this paper I argue that although organisms and machines resemble each other in some basic respects, they are actually very different kinds of systems. I submit that the (...) most significant difference between organisms and machines is that the former are intrinsically purposive whereas the latter are extrinsically purposive. Using this distinction as a starting point, I discuss a wide range of dissimilarities between organisms and machines that collectively lay bare the inadequacy of the MCO as a general theory of living systems. To account for the MCO’s prevalence in biology, I distinguish between its theoretical, heuristic, and rhetorical functions. I explain why the MCO is valuable when it is employed heuristically but not theoretically, and finally I illustrate the serious problems that arise from the rhetorical appeal to the MCO. (shrink)

The recent development and growth oforganic livestock farming and the relateddevelopment of national and internationalregulations has fueled discussions amongscientists and philosophers concerning theproper conceptualization of animal welfare.These discussions on livestock welfare inorganic farming draw on the conventionaldiscussions and disputes on animal welfare thatinvolve issues such as different definitions ofwelfare (clinical health, absence of suffering,sum of positive and negative experiences,etc.), the possibility for objective measuresof animal welfare, and the acceptable level ofwelfare. It seems clear that livestock welfareis a value-laden concept and (...) that animalwelfare science cannot be made independent ofquestions of values and ethics. The questioninvestigated here is whether those values thatunderpin organic farming, in particular, alsoaffect the interpretation of livestock welfare,and, if so, how. While some of the issuesraised in connection with organic farming arerelatively uncontroversial, others are not. Theintroduction of organic farming values seems tointroduce new criteria for what counts as goodanimal welfare, as well as a different ethicalbasis for making moral decisions on welfare.Organic farming embodies distinctive systemicor communitarian ethical ideas and the organicvalues are connected to a systemic conceptionof nature, of agriculture, of the farm, and ofthe animal. The new criteria of welfare arerelated to concepts such as naturalness,harmony, integrity, and care. While the organicvalues overlap with those involved in theconventional discussion of animal welfare, someof them suggest a need to set new prioritiesand to re-conceptualize animal welfare – forexample, with respect to ``naturalness,'''' inrelation to the possibilities for expression ofnatural behavior and in relation to animalintegrity as a concept for organismic harmony.The organic perspective also seems to suggest awider range of solutions to welfare problemsthan changes in farm routines or operations onthe animals. The systemic solutions include thechoice and reproduction of suitable breeds,changes in the farm structure, and changes inthe larger production and consumption system – including consumer perceptions andpreferences. But the organic values may alsocall for sacrifices of individual welfare in aconventional sense in order to advance welfarefrom the perspective of organic farming.Whether this is good or bad cannot be decidedwithout entering into an inquiry and discussionof the values and ethics involved. (shrink)

For a while, life and environment have been regarded as two separate subjects, but recently life and environment are to be seen as different aspects of one single theme. There are able philosophers who maintain the connection of the two but Seokheon Ham is believed to present a more coherent case. To him, integration is not merely a property which is unifying various elements, but it has a deep ontological structure seen in his utterance “there is not a (...) thing in the world which does not have a reason to exist”. He is providing a model of deep integration by equivalently linking life and sense. And he offers apparent arguments of oneness as integration of animates and inanimates, seeds as an example of integration of sense and life, and suffering as a historical integration. But Ham’s arguments will be strengthened by philosophizing the notion of integration. Fortunately, I would suggest that the clue is found in the conception of integration of Zhungyong. I will take the major thrust of the book to be five theses: (1) integration of a thing is the capacity to realize its embedded objective in its interactions with all other things; (2) ‘mind’ denotes the capacity of humans as well as the capacity of all other entities: (3) integration is a capacity not only of humans but also of all other entities; (4) if the evolution demonstrates the history of species as the fittest, then the history expresses the evolution of life forms of intelligence and justice; (5) integration of an entity is a disposition to realize its embedded objective in the context of its interconnections with all others at a particular time and place. The ontology of integration I am submitting may be shown to be an alternative to traditional physicalism. The integrational ontology may be seen as virtuous in that it is coherent with the informational view of the contemporary culture and with the caring need for those who suffer. (shrink)

abstract Numerous measures have been proposed to change the collection procedure in order to increase the supply of organ donations. One such proposal is to give the candidate donors the right to direct their organs to groups of recipients characterised by specific features like sex, age, disease and geographic location. Four possible justifications for directed donation of organs are considered: the utilitarian benefit, the egalitarian principle of justice, the maximin principle of justice and the autonomy principle. It is concluded that (...) none of these principles justifies the acceptance of designated donations. When potentially life‐saving resources are distributed, only a pure egalitarian distribution is in agreement with the principle of justice.s. (shrink)

This paper aims to identify the key characteristics of model organisms that make them a specific type of model within the contemporary life sciences: in particular, we argue that the term “model organism” does not apply to all organisms used for the purposes of experimental research. We explore the differences between experimental and model organisms in terms of their material and epistemic features, and argue that it is essential to distinguish between their representational scope and representational target. We also (...) examine the characteristics of the communities who use these two types of models, including their research goals, disciplinary affiliations, and preferred practices to show how these have contributed to the conceptualization of a model organism. We conclude that model organisms are a specific subgroup of organisms that have been standardized to fit an integrative and comparative mode of research, and that it must be clearly distinguished from the broader class of experimental organisms. In addition, we argue that model organisms are the key components of a unique and distinctively biological way of doing research using models.Keywords: Experimental organism; Genetics; Model organism; Modeling; Philosophy of biology; Representation. (shrink)

Unethical behavior in organizations has garnered more and more attention in the last decades but most of the scholarly work has used a static approach relying on methodological individualism and a mechanistic worldview when studying this topic. The process of moral disengagement and organizational culture have been linked to the prevalence of unethical behavior earlier, but this paper uses a complexity-informed systems perspective to explore the dynamic relationship of these concepts and aims to improve our understanding of the often unnoticeable, (...) step-by-step process through which organizational cultures can become conducive to unethical behavior. Organizations are conceptualized as complex adaptive systems in which transformative and stabilizing processes based on feedback loops take place continuously. It is discussed how these processes can lead to a phase transition driving organizations towards a state where unethical behavior is the general norm. The process is illustrated through real-life examples. (shrink)

A provocative question has emerged since the Supreme Court of Canada’s decision on assisted dying: Should Canadians who request, and are granted, an assisted death be considered a legitimate source of transplantable organs? A related question is addressed in this paper: is controlled organ donation after assisted death (cDAD) more or less ethically-problematic than standard, controlled organ donation after circulatory determination of death (cDCDD)? Controversial, ethics-related dimensions of cDCD that are of relevance to this research question are explored, and morally-relevant (...) distinctions between cDAD and cDCD are identified. In addition, a set of morally-relevant advantages of one practice over the other is uncovered, and a few potential, theoretical issues specifically related to cDAD practice are articulated. Despite these concerns, the analysis suggests a counterintuitive conclusion: cDAD is, overall, less ethically-problematic than cDCDD. The former practice better respects the autonomy interests of the potential donor, and a claim regarding irreversibility of cessation of the donor’s circulatory function in the cDAD context can be supported. Further, with cDAD, there is no possibility that the donor will have negative sensory experiences during organ procurement surgery. Although the development of appropriate policy-decision and regulatory approaches in this domain will be complex and challenging, the comparative ethical analysis of these two organ donation practices has the potential to constructively inform the deliberations of relevant stakeholders, resource persons and decision makers. (shrink)

It is almost unanimously acknowledged that the formation of Hegel’s philosophy was largely determined by the appropriation and further development of some fundamental achievements of Kant’s transcendental idealism - first of all his polemic against the “old metaphysics” or, as Hegel also said, the “empty metaphysics of the understanding”. The most decisive assumption of this metaphysics consisted, indeed, in the belief that the totality of our universe could be exhaustively resolved into a plurality of isolated entities, devoid of any “internal,” (...) essential, mutual relations. Each entity was, as a consequence, considered to be only abstractly self-identical and so different from any other. In such a perspective, the absolute, the infinite, the divine, could not but be conceived as being substantially alien to the human mind’s innermost life and essence, as a merely motionless object, absolutely transcendent to the self-creative process in which our rational subjectivity essentially consists. Kant’s critique - especially by virtue of his conception of knowledge as an “a priori synthesis” of intuition and category, of experience and concept, which finds the ultimate condition of its possibility not in its conformity to a presupposed objectivity, but precisely in the original unity of self-consciousness, the “I-think-in general” - has certainly by now rendered unsustainable the strict dualism typical of such a metaphysics, and in particular its pretension of rationally “demonstrating” the existence and the most general properties of the alleged merely transcendent absolute. Whereas Kant’s idealism seems nevertheless to limit itself to the statement and foundation of this simply critical and negative outcome of the transcendental analysis of our knowledge, the ultimate aim of Hegel’s whole philosophy consists rather in the attempt explicitly and systematically to develop a conception of the universe, according to which the universe, far from dividing into a plurality of absolutely different and exclusive entities, instead constitutes itself as a unique, absolute, organic totality, in which any immediate difference and opposition tends to merge, to “reconcile” itself in a superior and deeper “dialectical” unity, which is both divine and human, infinite and finite, identical and different, ideal and real, eternal and in a process of becoming, transcendent and immanent. Every one of its determinate aspects and grades of development, every element into which it differentiates itself, thus turns out to be intimately immanent in, and connected with, every other, and finally in and with the absolute totality itself. Totum in toto et in qualibet parte. “Outside” of such unique, concrete totality, there appear to be but empty, irrational, unreal abstractions: first of all the A = A of formal logic and the absolutely transcendent God of the “old metaphysics.”. (shrink)

This paper defends an ‘opt-out’ scheme for organ procurement, by distinguishing this system from ‘presumed consent’ (which the author regards as an erroneous justification of it). It, first, stresses the moral importance of increasing the supply of organs and argues that making donation easier need not conflict with altruism. It then goes on to explore one way that donation can be increased, namely by adopting an opt-out system, in which cadaveric organs are used unless the deceased (or their family) registered (...) an objection. Such policies are often labelled ‘presumed consent’, but it is argued that critics are right to be sceptical of this idea—consent is shown to be an action, rather than a mental attitude, and thus not something that can be presumed. Either someone has consented or they have not, whatever their attitude to the use of their organs. Thankfully, an opt-out scheme need not rest on the presumption of consent. Actual consent can be given implicitly, by one's actions, so it is argued that the failure to register an objection (given certain background conditions) should itself be taken as sign of consent. Therefore, it is permissible to use the organs of someone who did not opt out, because they have—by their silence—actually consented. (shrink)

This case study discusses the economic, legal, and ethical considerations for conducting clinical trials in a controversial context. In 2010, pharmaceutical giant Roche received a shame award by the Swiss non-governmental organization Berne Declaration and Greenpeace for conducting clinical trials with organs taken from executed prisoners in China. The company respected local regulations and industry ethical standards. However, medical associations condemned organs from executed prisoners on moral grounds. Human rights organizations demanded that Roche ended its clinical trials in China (...) immediately. Students are expected to review the economic and ethical issues regarding the outsourcing of clinical trials to controversial human rights contexts, and discuss how to make business decisions when there are conflicts between making profit and ethical considerations. Was Roche complicit in the human rights violations that were related to its clinical trials? Future patients might benefit from these clinical trials. Do profit and the greater good, in general, trump morals? (shrink)

The question of who exactly is responsible for an organization’s actions cannot be too carefully considered, as a clear understanding of this point is crucial from ethical, moral, managerial, and public perspectives. This article discusses how to justify a non-participant member’s responsibility for the actions of other group members, establishing collective responsibility. The article develops a novel context-depended framework that solves this problem by supplying good grounds for perceiving organizations as organic entities, which is adequate for establishing collective (...) responsibility. I suggest that to be responsible for the actions of an organization, one has to belong to that organization, even if one has not taken any part at any level in group actions. The more regular concept of causal responsibility is not applicable here since it cannot account for the responsibility of non-participant members. (shrink)

Sign-theoretical concepts have been used in research into the nature of living systems, not only by biologists, semioticians, and philosophers, but also by scientists who analyze organisms from the perspective of Decision Theory. Decision Theory (DT) describes both the external behavior and the internal information-processing of any kind of agent in terms of problem solving. Such “problem solving” is considered a complex process of: (1) defining a goal in an environment, (2) selecting the means to reach the defined goal, and (...) (3) controlling the effects of said selected means on the environment. The hypothesis that problem-solving agents are, first, physical entities and, second, sign-using systems is one of the most influential ideas in Decision Theory. This idea has been developed under the name of the ‘Physical Symbol System Hypothesis’ (PSSH) since the 1950s, particularly by two American scientists, Allen Newell and Herbert A. Simon, who did interdisciplinary research in cognitive science, artificial intelligence, economics, and decision theory. This paper first gives a short overview of the basic semiotic theory that underlies Newell’s and Simon’s work, and then offers some ideas on a specifically biosemiotic use of the Physical SymbolSystem Hypothesis. (shrink)

The ideas of contextuality and of compositionality were discussed at the beginnings of the nineteenth century in Germany, but the contextuality was the significant one. In 1880, Wundt published a work called Logik, comprising two volumes, which evolved to the German standard text on logic. Gottlob Frege, a German mathematician, logician, and philosopher, presented contextuality as his basic principle; his solution of the foundational problems is based upon it, he meant the principle literally, and would have rejected compositionality. He introduced (...) the distinction between sense and reference in his paper, “Über Sinn und Bedeutung” in 1892. He did not accept the notion the reference of an expression; instead, his approach is based upon the notion the reference of an expression in a given sentence. In the period before Tarski, logics were regarded as deductive theories. Tarski made an important step with his paper on “Truth in formalized languages,” in which he characterized the notion of a true sentence in a purely semantic way. (shrink)

Although the knowledge about biological systems has advanced exponentially in recent decades, it is surprising to realize that the very definition of Life keeps presenting theoretical challenges. Even if several lines of reasoning seek to identify the essence of life phenomenon, most of these thoughts contain fundamental problem in their basic conceptual structure. Most concepts fail to identify either necessary or sufficient features to define life. Here, we analyzed the main conceptual frameworks regarding theoretical aspects that have (...) been supporting the most accepted concepts of life, such as (i) the physical, (ii) the cellular and (iii) the molecular approaches. Based on an ontological analysis, we propose that Life should not be positioned under the ontological category of Matter. Yet, life should be better understood under the top-level ontology of “Process”. Exercising an epistemological approach, we propose that the essential characteristic that pervades each and every living being is the presence of organic codes. Therefore, we explore theories in biosemiotics and code biology in order to propose a clear concept of life as a macrocode composed by multiple inter-related coding layers. This way, as life is a sort of metaphysical process of encoding, the living beings became the molecular materialization of that process. From the proposed concept, we show that the evolutionary process is a fundamental characteristic for life’s maintenance but it is not necessary to define life, as many organisms are clearly alive but they do not participate in the evolutionary process (such as infertile hybrids). The current proposition opens a fertile field of debate in astrobiology, epistemology, biosemiotics, code biology and robotics. (shrink)

Barbieri introduced and developed the concept of organic codes. The most basic of them is the genetic code, a set of correspondence rules between otherwise unrelated sequences: strings of nucleotides on the one hand, polypeptidic chains on the other hand. Barbieri noticed that it implies ‘coding by convention’ as arbitrary as the semantic relations a language establishes between words and outer objects. Moreover, the major transitions in life evolution originated in new organic codes similarly involving conventional rules. (...) Independently, dealing with heredity as communication over time and relying on information theory, we asserted that the conservation of genomes over the ages demands that error-correcting codes make them resilient to casual errors. Moreover, the better conservation of very old parts of the genome demands that they result from combining successively established nested codes such that the older an information, the more numerous component codes protect it. Barbieri’s concept of organic code and that of genomic error-correcting code may seem unrelated. We show however that organic codes actually entail error-correcting properties. Error-correcting, in general, results from constraints being imposed on a set of sequences. Mathematical equalities are conveniently used in communication engineering for expressing constraints but error correction only needs that constraints exist. Biological sequences are similarly endowed with error-correcting ability by physical-chemical or linguistic constraints, thus defining ‘soft codes’. These constraints are moreover presumably efficient for correcting errors. Insofar as biological sequences are subjected to constraints, organic codes necessarily involve soft codes, and their successive onset results in the nested structure we hypothesized. Organic codes are generated and maintained by means of molecular ‘semantic feedback loops’. Each of these loops involves genes which code for proteins, the enzymatic action of which controls a function needed for the protein assembly. Taken together, thus, they control the assembly of their own structure as instructed by the genome and, once closed, these loops ensure their own conservation. However, the semantic feedback loops do not prevent the genome lengthening. It increases both the redundancy of the genome and the information quantity it bears, thus improving the genome reliability and the specificity of the enzymes, which enables further evolution. (shrink)

Organ transplantation is an accepted therapy for major organ failure, but it depends on the availability of viable organs. Most organs transplanted in the U.S. come from either "brain-dead" or living related donors. Recently organ procurement from patients pronounced dead using cardiopulmonary criteria, so-called "non-heart-beating cadaver donors" (NHBCDs), has been reconsidered. In May 1992, the University of Pittsburgh Medical Center (UPMC) enacted a new, complicated policy for procuring organs from NHBCDs after the elective removal of life support. Seventeen months (...) later only one patient has become a NHBCD. This article describes her case and the results of interviews with the health care team and the patient's family. The case and interviews are discussed in relation to several of the ethical concerns previously raised about the policy, including potential conflicts of interest, the definition of cardiopulmonary death, and a possible net decrease in organ donation. The conclusion is reached that organ procurement from non-heart-beating cadavers is feasible and may be desirable both for the patient's family and the health care providers. (shrink)

In §66 of the Critique of the Teleological Power of Judgment, Kant presents a maxim for judging organisms. The maxim is a hybrid of empirical and a priori elements: Kant claims that though it is derived from experience, it asserts universality and necessity. The author substantiates the maxim and account for its hybrid nature by reconstructing Kant’s view, anchoring it in the text of and philosophical positions from neighboring sections of the Analytic. The reconstruction exposes a proper role for (...) reflective judgment, and for a relation between reason and the faculty of understanding; it shows how Kant’s conception of organisms and species concepts, his general conception of matter, and the systematicity of his conceptual hierarchy are fundamental to justifying the maxim. (shrink)

It has been argued that organs should be treated as individual tradable property like other material possessions and assets, on the basis that this would promote individual freedom and increase efficiency in addressing the shortage of organs for transplantation. If organs are to be treated as property, should they be inheritable? This paper seeks to contribute to the idea of organs as inheritable property by providing a defence of a default of the family of a dead person as inheritors (...) of transplantable organs. In the course of discussion, various succession rules for organs and their justifications will be suggested. We then consider two objections to organs as inheritable property. Our intention here is to provoke further thought on whether ownership of one's body parts should be assimilated to property ownership. (shrink)

The dead donor rule (DDR) prohibits retrieval protocols that would be lethal to the donor. Some argue that compliance with it can be maintained by satisfying the requirements of double‐effect reasoning (DER). If successful, one could support organ donation without reference to the definition of death while being faithful to an ethic that prohibits intentionally killing innocent human life. On the contrary, I argue that DER cannot make lethal organ donation compatible with the DDR, because there are plausible ways (...) it fails DER's requirements. A key takeaway is that the theories of intention and proportionality assumed in DER matter for its plausibility as a constraint on practical reasoning. (shrink)

The distinctness of each person’s life and experience is an important consideration in dominant accounts of how democratic institutions should distribute basic rights and liberties. Drawing on recent social movements, philosophers like Iris Marion Young, Miranda Fricker, and Axel Honneth have nonetheless drawn attention to the distinctive claims and challenges that plurality and difference entrain in democratic societies by analysing how the dominant discourses on rights and justice tend to elide, obscure, or reify the lived experiences of individuals belonging (...) to disadvantaged and oppressed groups. In this essay, I offer an independent justification for why we should take such lived experiences seriously. I show how the lived experiences of disadvantaged and oppressed individuals can be a resource for deep and meaningful social change. I propose a distinctive kind of social change in which the disadvantaged and oppressed themselves drive the process of transformation whereby they change the oppressive frames of difference relating to their race, class, sex, or ability. I call this kind ‘organic social change’. I also show that organic social change is distinctively important in that the disadvantaged and oppressed get to enact an empowering mode of cooperation that harnesses their singularities when they are the ones driving the process of their own and one another’s transformations. (shrink)

The COVID-19 crisis has renewed interest in alternative forms of organizing business and investment but our understanding of how these organizations can transform social systems is limited. The purpose of this article is to contribute to this understanding. In the context of one of the greatest transfers of wealth in global retail history that could see unprecedented numbers of businesses close or sold to distant, private interests, the article performs a thought experiment using the analogy of a commercial trust (...) to encourage new ideas and critical reflection on community wealth building. The article introduces systems hijacking—a process of leveraging incumbent forms and systems in which they are embedded for new purposes—as an analytically useful concept for understanding how alternative organizations can transform social systems. The article finds organizational governance is necessary to transcend structural deficiencies in inherited or borrowed forms to make way for transformation. (shrink)

This brief and engaging introductory text treats philosophy as a dramatic and continuous story--a conversation about humankind's deepest and most persistent concerns, in which students are encouraged to participate. Tracing the exchange of ideas between history's key philosophers, Philosophical Conversations: A Concise Historical Introduction demonstrates that while constructing an argument or making a claim, one philosopher almost always has others in mind. The book addresses the fundamental questions of human life: Who are we? What can we know? (...) How should we live? and What sort of reality do we inhabit? Throughout, author Norman Melchert provides a generous selection of excerpts from major philosophical works and makes them more easily understandable with his lucid explanations. Extensive cross-references highlight the organizing themes and show students how philosophers have responded to each other's arguments. A more concise edition of Norman Melchert's The Great Conversation: A Historical Introduction to Philosophy, Fifth Edition, Philosophical Conversations is designed to be especially accessible and visually attractive to first- and second-year college students in introduction to philosophy courses. Enhanced by numerous pedagogical features, it offers: * Shorter and/or simplified presentations of much of the material * A second color that enlivens the text and makes it more visually interesting * An expanded art program featuring more than 100 photographs, illustrations, and cartoons * Classic art at the opening of each chapter * Numerous brief quotations from poets, politicians, and thinkers that underscore philosophical points and stimulate thought * Explanatory footnotes and basic study questions throughout * "Questions for Further Thought" at the end of each chapter * Key terms, boldfaced at their first appearance and collected at the end of each chapter and in a detailed glossary at the back of the book * "Sketches"--which provide glimpses of the ideas of various philosophers not already discussed in detail in the narrative--and "Profiles," which offer more in-depth looks at several thinkers, philosophical schools, and movements including Taoism, Zen, Jean-Paul Sartre, and Iris Murdoch * An Instructor's Manual and Test Bank on CD that highlights essential points and offers numerous exam questions. (shrink)

Cognitive neuroscience has been driven by the idea that by reductionist analysis of mechanisms within a solitary brain one can best understand how the human mind is constituted and what its nature is. The brain thus came to appear as the creator of the mind and the experienced world. In contrast, the paper argues for an ecological view of mind and brain as both being embedded in the relation of the living organism and its environment. This approach is crucially (...) dependent on a developmental perspective: the brain is conceived as a plastic system of open loops that are formed in the process of life and closed to full functional cycles in every interaction with the environment. Each time a new disposition of coherent neural activity is formed through repeated experience, structures of the mind are imprinted onto the brain. The brain becomes a mediating organ or a window to the mind, for it is structured by the mind itself. (shrink)

The organ shortage is commonly presented as having a clear solution, increase the number of organs donated and the problem will be solved. In the light of the Northern Ireland Assembly’s consultation on moving to an opt-out organ donor register this article focusses on the social factors and complexities which impact strongly on both the supply of, and demand for, transplantable organs. Judging by the experience of other countries presumed consent systems may or may not increase donations but have not (...) met demand. Donation rates have risen considerably in all parts of the UK recently but there is also an increasing demand for organs. Looking at international donation rates and attitudes, future demand for organs and education on donation, the question is whether the organ shortage could ever be met. The increase in longevity, in rates of diabetes and obesity and in alcohol related liver disease all contribute both to increased demand for transplants, and re-transplants, and a reduction in the number of usable organs. It is unlikely that demand could ever be met, since, if supply was unlimited, the focus would move to financial resources and competing demands on the health care budget in a publicly funded health system. These factors point to the need to focus on ways of reducing, or at least stabilizing, demand where lifestyle factors contribute to the underlying disease. (shrink)

Recent advancements in stem-cell research have given scientists hope that new technologies will soon enable them to grow a variety of organs for transplantation into humans. Though such developments are still in their early stages, romantic prognosticators are hopeful that scientists will be capable of growing fully functioning and complex organs, such as hearts, kidneys, muscles, and livers. This raises the question of whether such profound medical developments might have other potentially fruitful applications. In the spirit of innovation, this paper (...) examines the ethical ramifications of a spin-off technology that has just begun being considered by scientists and enthusiastic entrepreneurs: animal organs grown, independently of their host animals, for food. -/- Most importantly, this paper presents the homegrown organs market as a philosopher's Gedankenexperiment come true. By comparing three of the primary arguments against the use of animals for meat production -- Peter Singer's Utilitarianism, Tom Regan's Kantianism, and Cora Diamond's non-cognitivism -- this paper proposes that the case of organs grown in a laboratory for food further accentuates the point that the critical moral difference between an animal and a slab of meat lies in the way in which the animal interacts with us, not in specific attributes or values intrinsic to that animal. It suggests that our main impetus for not eating, and even for protecting, animals ought to be grounded in our sense of who we are, in our own practical identity as ethical agents, which develops over a long course of interactive interrelations with human and non-human others. (shrink)

In The Philosophic Consultant, acclaimed business consultant, philosopher, and author Peter Koestenbaum links deep insights of philosophy with practical business issues. Throughout this one-of-a-kind resource, Koestenbaum shows consultants and human resource practitioners how they can foster philosophical leadership within their organizations to positively affect the business environment. The book promises tangible results-- credibility, trust, and thoughtful attention-- and demonstrates how to apply philosophy, share knowledge with others, and use this newfound thoughtfulness to achieve bottom-line results.

Post-translational histone modifications and their biological effects have been described as a ‘histone code’. Independently, Barbieri used the term ‘organic code’ to describe biological codes in addition to the genetic code. He also provided the defining criteria for an organic code, but to date the histone code has not been tested against these criteria. This paper therefore investigates whether the histone code is a bona fide organic code. After introducing the use of the term ‘code’ in biology, (...) the criteria a putative organic code such as the histone code must conform to in order to be recognised as an organic code are described. Our current knowledge of histones and their major post-translational modifications, and the specific protein binding domains that recognise and translate these into specific biological effects, is then reviewed in detail. The histone modification system is then placed in the context of an organic code and it is concluded that it fulfils all the requirements of an organic code. The marks produced on histones by processes such as acetylation and methylation act as organic signs that are translated into unique biological effects, their biological meanings. These translations are accomplished by effector proteins that consist of a binding domain that recognises a specific histone mark and a regulatory domain that mediates the biological effect. Crucially, these domains can be experimentally interchanged between different effector proteins, thus altering the rules that specify the relationships between sign and meaning. The effector proteins therefore fulfil the role of adaptor molecules. (shrink)

Aristotle’s philosophy of mind is often understood as anticipating present-day functionalist approaches to the mental. In Aristotle on the Sense-Organs Johansen argues at length that such interpretations of what Aristotle has to say about the senses are untenable. First, Aristotle does not allow that the matter of a sense-organ can be identified without reference to the form or function of the organ, so sense-organs are not compositionally plastic. Second, Aristotle’s conception of sense-perception is radically different from anything a philosopher today, (...) functionalist or not, would find credible: acts of sense-perception on Aristotle’s view do not require material changes in the sense-organs. Developed carefully throughout all six chapters, Johansen’s defense of this latter claim is the most significant part of the book, and it will be my focus here. (shrink)

Traditionally, it has been supposed that the central object of Biology are ‘organisms’. The expression “organism” is relatively recent in the use that it has nowadays –it was introduced by the authors of the German Idealism– but corresponds to a very traditional notion. An ‘organism’ is a substance composed by a plurality of materials organized by the same substance that acts upon itself to persist in time, in order to a finality that is the organism itself. To make intelligible an (...) organism seems indispensable its order to an end. This teleological perspective, nevertheless, is unacceptable for the reductivist perspective of Biology, prevalent since the triumph of what has been called the “Modern Synthesis” the first half of last century. It has been proposed, for that reason, to substitute the traditional idea of ‘organism’ by that of ‘Darwinian individual’ (cf. Godfrey-Smith, 2009), that could offer a more adequate perspective of the object of Biology. The object of this science could not be organisms, but individuals that can enter the Darwinian evolutionary drift. In this work it is explained why a hiatus persists between organisms teleologically oriented and a Darwinian individual. The Darwinian perspective leaves aside the central character of the object of Biology: life. (shrink)

Organ shortage constitutes an unsolved problem for every country that offers transplantation as a therapeutic option. Besides the largely implemented donation model and the eventually implemented market model, a theorized automatic organ procurement model has raised a rich debate in the legal, medical and bioethical community, since it could show a higher potential to solve organ shortage. In this paper, we study the main arguments for and against this model. We show how, in the light of empirical data extracted from (...) countries with a universal health care system, its implementation could lead to a positive impact on organ procurement rates. Three factors are envisioned as fundamental in the comprehension and a possible regulation of the automatic organ procurement model: the lack of recognition of the conscientious objection, the preservation of the right to choose end of life conditions, and the need to avoid incentives for families or healthcare professionals. (shrink)

Definition of the problem: Even after the new German legislation about organ donors and transplantation (“information solution”), the question of criteria for distributing the organs is still not solved. The various alternatives to solve this problem face different social acceptance and economic efficiency.Arguments: Medical criteria (e.g. HLA compatibility) and non-medical criteria (e.g. willingness to pay of the patients) are valued on the basis of generally accepted objectives (e.g. equal access to health services or low costs). As an innovative form of (...) organ distribution systems the club solution is introduced. It allows the donor to realise preferences regarding use of the organs.Conclusion: Scoring systems may help to increase the transparency of organ allocation. From an economic point of view medical criteria have to be weighted more than non-medical criteria. (shrink)

Cadaver organs should be automatically availableThe shortage of donor organs and tissue for transplantation constitutes an acute emergency which demands radical rethinking of our policies and radical measures. While estimates vary and are difficult to arrive at there is no doubt that the donor organ shortage costs literally hundreds of thousands of lives every year. “In the world as a whole there are an estimated 700 000 patients on dialysis . . .. In India alone 100 000 new patients present (...) with kidney failure each year” . Almost “three million Americans suffer from congestive heart failure . . . deaths related to this condition are estimated at 250 000 each year . . . 27 000 patients die annually from liver disease . . .. In Western Europe as a whole 40 000 patients await a kidney but only . . . 10 000 kidneys”1 become available. Nobody knows how many people fail to make it onto the waiting lists and fail to register in the statistics. “As of 24th November 2002 in the United Kingdom 667 people have donated organs, 2055 people have received transplants, and 5615 people are still awaiting transplants.”2Conscious of the terrible and unnecessary tragedy that figures like these represent I have been advocating for more than 20 years now some radical measures to stem this appalling waste of human life. The measure which is the subject of Hamer and Rivlin’s paper 3 concerns the automatic availability of all cadaver organs—a measure, which I first advocated publicly in 1983.4THE AUTOMATIC AVAILABILITY OF DONOR ORGANSWe need to begin by being clear about just what it is I propose and why. At the moment in the United Kingdom we …. (shrink)

Organ transplantation remains one of modern medicine's remarkable achievements. It saves lives, improves quality of life, diminishes healthcare expenditures in end-stage renal patients, and enjoys high success rates. Yet the promise of transplantation is substantially compromised by the scarcity of organs. The gap between the number of patients on waiting lists and the number of available organs continues to grow. As of January 2006, the combined waiting list for all organs in the United States was 90,284. Unfortunately, thousands of (...) potential organs are lost each year, primarily due to lack of consent to donation from the deceased before death, or from the family thereafter. Only fifty percent of potential donors – the “conversion” rate – become actual donors. The costs attributed to organ shortage are substantial – Medicare paid over $15.5 billion in 2002 for treating patients with end-stage renal-disease, who predominate on organ waiting lists. (shrink)

A proposal to allow prisoners to save their lives or to be eligible for commutation of sentence by donating kidneys for transplantation has been a subject of controversy in the Philippines. Notwithstanding the vulnerabilities associated with imprisonment, there are good reasons for allowing organ donations by prisoners. Under certain conditions, such donations can be very beneficial not only to the recipients but to the prisoners themselves. While protection needs to be given to avoid coercion and exploitation, overprotection has to be (...) avoided. The prohibition on the involvement of prisoners in organ transplantation constitutes unjustified overprotection. Under certain conditions, prisoners can make genuinely independent decisions. When it can be reasonably ascertained that they are able to decide freely, society should recognise an obligation to help them implement their decisions, such as when they intend to donate an organ as a way of asserting their religious faith and performing a sacrifice in atonement for their sins. (shrink)

This chapter gives an outline of the development of the human organ transplant system in Hong Kong, whose key features are a soft opt-in system and strict prohibitions on commercial dealings in human organs for transplant. It is argued that under such a system, there is a lack of incentives for either cadaveric or living organ donations and for family members to endorse deceased donation. This argument is followed by an investigation of the shortage of organ donations in Hong Kong, (...) the limited success of the government promotion to improve the number of donations, and a discussion of new alternatives for improvement that have been initiated or proposed. It is argued that the feasibility and effectiveness of these alternatives are limited and uncertain. More radical reform of the existing system in terms of honorary, compensationalist, and familist incentives is needed and they all need to be taken into consideration. (shrink)

Lethal organ donation is a hypothetical procedure in which vital organs are removed from living donors, resulting in their death. An important objection to lethal organ donation is that it would infringe the prohibition on doctors intentionally causing the death of patients. I present a series of arguments intended to undermine this objection. In a case of lethal organ donation, the donor’s death is merely foreseen, and not intended.

Arguments against directed altruistic living organ donation are too weak to justify a ban. Potential donors who want to specify the non-related person or group of persons to receive their donated kidney should be accepted. The arguments against, based on considerations of motivation, fairness and (non-)anonymity (e.g. those recently cited by an advisory report of the Dutch Health Council), are presented and discussed, as well as the Dutch Governments response. Whereas the Government argues that individuals have authority with regard to (...) the allocation of their organs, partial considerations have not been sufficiently explored. In addition, it is argued that partial relationships govern human life, are significant and should be valued highly. These relationships are at the core of accepted living kidney donation between relatives (family members, partners, friends). Respecting the particular act of living donation goes beyond respect for autonomy; it touches upon our personal and social identity. Donation, e.g. of a kidney, is not undertaken strictly for the benefit of the recipient, but also to meet the moral standards we wish to set for ourselves. This consideration, rooted in a view of moral identity, provides the basis for many forms of directed donation that are both partial and justified. If the importance of this is not recognized, social policies can be neither adequate nor effective. (shrink)

We explore the ethics of using motivational interviewing, an evidence-based, client-centred and directional counselling method, in conversations with next of kin about deceased solid organ donation. After briefly introducing MI and providing some context around organ transplantation and next of kin consent, we describe how MI might be implemented in this setting, with the hypothesis that MI has the potential to bring about a modest yet significant increase in next of kin consent rates. We subsequently consider the objection that (...) using MI in this context would be manipulative. Although we cannot guarantee that MI would never be used in a problematically manipulative fashion, we conclude that its use would, nevertheless, be permissible as a potential means to increase next of kin consent to deceased solid organ donation. We propose that MI be trialled in consent situations with next of kin in nations where there is widespread public support for organ donation. (shrink)

Like other groups associated with social movements, rape crisis centers have been judged co-optive by some and progressive by others. This article argues that organizational theory yields fuller explanations of their dynamics and character. In a case study, two subcultures—dubbed the politicized and service perspectives—developed and epitomized fundamentally different approaches to sexual violence. These subcultures emerged for a number of reasons, including the organization's goals, the character of the fiminist movement, and organizational features such as permeability, a broad constituency, a (...) collective goods orientation, and an emphasis on open discourse. This article argues that similar organizational and environmental features in rape crisis centers and other social movement-related organizations are associated with organizational fluidity and conflict. While these groups may not be cohesive and stable actors for broad social change, they contribute incrementally to long-term shifts in gendered social structures. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Kennedy Institute of Ethics Journal 13.1 (2003) 53-64 [Access article in PDF] Incentives for Providing Organs Patricia Milmoe McCarrick and Martina Darragh After a contentious debate at its 2002 annual meeting, the American Medical Association's House of Delegates voted to endorse the opinion of its Council on Ethical and Judicial Affairs that the impact of financial incentives on organ donation should be studied (Josefson 2002). The shortage of organs (...) for transplantation has been an ongoing problem for more than 20 years. In June1981, Representative Philip Crane (R-IL) introduced legislation in the U.S. House of Representatives proposing a $25,000 income tax deduction and a $25,000 estate tax exclusion for donating an organ (Tax Incentives 1981). Still the National Organ Transplant Act enacted in October 1984 prohibited the offering of any "valuable consideration" in return for organs (United States 1984).The developments of a legal market for tissues in the United States and a black market for organs around the world have raised the question of whether donation without compensation is the only ethically viable option. Some critics of the current system claim reliance on donation actually promotes a black market in organs (Kaserman and Barnett 2002, p. 38; Palmer 1999, p. 36). In addition, a new set of compensation issues has arisen as living kidney donor transplantations begin to rival those performed with cadaveric organs (United States 2001).As a result, current suggestions for incentives go far beyond the traditional death benefit payment to include such ideas as medals of honor for donors, reimbursement for funeral expenses, exchange programs for organ donation, and special medical insurance for living organ donors. Numerous bills introduced into the 107th Congress have proposed such incentives (Delmonico et al. 2002.) In October 2002, the U.S. Department of Health and Human Services awarded $5.2 million in grants to study both clinical and behavioral interventions for increasing organ donations that do not involve incentives. The inspiration for some of the funded proposals comes from the successes of Spain's social services and the United Kingdom's clinical administration of organ procurement programs (Robeznieks 2002). [End Page 53]With a nod to evidence-based medicine, the underlying concern expressed in much of the current literature is that no idea for increasing the supply of organs should be discounted before it is studied. This bibliography provides a short introduction to the range of opinions expressed on the issue of incentives for providing organs.al-Mousawi, M.; Samhan, M.; al-Mezairee I.; Razzak, M.A.; and Khawari, F. Cadaver Organ Procurement in Kuwait. Transplantation Proceedings 31 (8): 3375-76, 1999.The authors describe a protocol that significantly increased cadaveric organ donation and credit it with fostering the expansion of an organ sharing program among the Arab Gulf states. Developed by Kuwaiti neurologists and anesthetists after a continuing education course on transplantation, the protocol places a special emphasis on the role of local transplant coordinators who facilitate the investigation of brain death cases by neurologists.Arnold, Robert; Bartlett, Steven; Bernat, James; et al. [Ethics Committee of the American Society of Transplant Surgeons] Financial Incentives for Cadaver Organ Donation: an Ethical Reappraisal. Transplantation 73 (8): 1361-67, 27 April 2002.To prepare for proposed studies of financial incentives for organ donation, the American Society of Transplant Surgeons convened a panel to develop a methodology for evaluating the ethics of such research. Comprised of organ procurement organization executives, physicians, surgeons, and ethicists, the panel generated a list of nine criteria for use in judging any incentives proposal. While opposed to direct payment or tax incentives for organ donation, a majority of the members support funeral expense reimbursement or charitable contributions as incentives that would not violate or undermine the ideal of altruism.Cameron, J. Stewart, and Hoffenberg, Raymond. The Ethics of Organ Transplantation Reconsidered: Paid Organ Donation and the Use of Executed Prisoners as Donors. Kidney International 55 (2): 724-32, February 1999.After reviewing arguments for and against payment for organ procurement, the authors apply these arguments to the specific case of obtaining organs from executed... (shrink)

This book offers an important study of Aristotle's theory of the sense-organs. It aims to answer two questions central to Aristotle's psychology and biology: why does Aristotle think we have sense-organs, and why does he describe the sense-organs in the way he does? The author looks at all the Aristotelian evidence for the five senses and shows how pervasively Aristotle's accounts of the sense-organs are motivated by his interest in form and function. The book also engages with the celebrated problem (...) of whether perception for Aristotle requires material changes in the perceiver. It argues that, surprisingly to the modern philosopher, nothing in Aristotle's description of the sense-organs requires us to believe in such changes. (shrink)

In Capital as Organic Unity, Mark E. Meaney argues “that the doctrinal content of Marx’s Grundrisse is indebted for its logical form to Hegel’s exposition of logical categories as found in the Wissenschaft der Logik”. Meaney builds upon an important work by Hiroshi Uchida which had already explored Marx’s debt in the Grundrisse to Hegel’s Logic. But beyond Uchida’s claims, Meaney maps the entire structure of the Grundrisse onto the parallel movements of Hegel’s larger Science of Logic. Meany’s text (...) contains seven chapters. Besides the introduction and conclusion, one chapter discusses money as being, two discuss capital as essence or the essence of capital, and two more discuss the concept of capital in its objective, conceptual completeness. Capital is for Marx a concrete manifestation of Hegel’s objectification of the concept. (shrink)

In this work, Collingridge offers a general philosophy of criticism. Many philosophers influenced by the ideas of Karl Popper have hoped to see an expansion from his view of the operation of criticism within science to a more general account of criticism, and, until now, moves in this direction have had only limited success. This book extends Popper's account of the role of criticism in science to many other areas of inquiry.

In their recent article, Glannon and Ross remind us that family members have obligations to help each other that strangers do not have. They argue, I believe correctly, that what creates moral obligations within families is not genetic relationship but rather a sharing of intimacy. For no one are these obligations stronger than they are for parents of young children. This observation leads the authors to the logical conclusion that organ donation by a parent to her child is not optional (...) but rather a prima facie duty. However, Glannon and Ross go a step further by suggesting that because parent-to-child organ donation is a duty, it cannot be altruistic. They assert that “altruistic acts are optional, nonobligatory…supererogatory…. Given that altruism consists in purely optional actions presupposing no duty to aid others, any parental act that counts as meeting a child's needs cannot be altruistic.” Here I think the authors go too far. (shrink)