This chapter contains sections titled: The Domains of Microevolution and Macroevolution Changing Meanings of Macroevolution An Expanding Hierarchy of Selection Origins of Novelty Mass Extinctions Is Evolution Uniformitarian? Conclusions Postscript: Counterpoint References.

In both biology and the human sciences, social groups are sometimes treated as adaptive units whose organization cannot be reduced to individual interactions. This group-level view is opposed by a more individualistic one that treats social organization as a byproduct of self-interest. According to biologists, group-level adaptations can evolve only by a process of natural selection at the group level. Most biologists rejected group selection as an important evolutionary force during the 1960s and 1970s but a positive literature (...) began to grow during the 1970s and is rapidly expanding today. We review this recent literature and its implications for human evolutionary biology. We show that the rejection of group selection was based on a misplaced emphasis on genes as "replicators" which is in fact irrelevant to the question of whether groups can be like individuals in their functional organization. The fundamental question is whether social groups and other higher-level entities can be "vehicles" of selection. When this elementary fact is recognized, group selection emerges as an important force in nature and what seem to be competing theories, such as kin selection and reciprocity, reappear as special cases of group selection. The result is a unified theory of natural selection that operates on a nested hierarchy of units. The vehicle-based theory makes it clear that group selection is an important force to consider in human evolution. Humans can facultatively span the full range from self-interested individuals to "organs" of group-level "organisms." Human behavior not only reflects the balance between levels of selection but it can also alter the balance through the construction of social structures that have the effect of reducing fitness differences within groups, concentrating natural selection (and functional organization) at the group level. These social structures and the cognitive abilities that produce them allow group selection to be important even among large groups of unrelated individuals. (shrink)

In both biology and the human sciences, social groups are sometimes treated as adaptive units whose organization cannot be reduced to individual interactions. This group-level view is opposed by a more individualistic one that treats social organization as a byproduct of self-interest. According to biologists, group-level adaptations can evolve only by a process of natural selection at the group level. Most biologists rejected group selection as an important evolutionary force during the 1960s and 1970s but a positive literature (...) began to grow during the 1970s and is rapidly expanding today. We review this recent literature and its implications for human evolutionary biology. We show that the rejection of group selection was based on a misplaced emphasis on genes as “replicators” which is in fact irrelevant to the question of whether groups can be like individuals in their functional organization. The fundamental question is whether social groups and other higher-level entities can be “vehicles” of selection. When this elementary fact is recognized, group selection emerges as an important force in nature and what seem to be competing theories, such as kin selection and reciprocity, reappear as special cases of group selection. The result is a unified theory of natural selection that operates on a nested hierarchy of units.The vehicle-based theory makes it clear that group selection is an important force to consider in human evolution. Humans can facultatively span the full range from self-interested individuals to “organs” of group-level “organisms.” Human behavior not only reflects the balance between levels of selection but it can also alter the balance through the construction of social structures that have the effect of reducing fitness differences within groups, concentrating natural selection (and functional organization) at the group level. These social structures and the cognitive abilities that produce them allow group selection to be important even among large groups of unrelated individuals. (shrink)

In this paper I propose a type-hierarchy approach to provide an intersubjective framework for the evaluation of evolutionary analogies. This approach develops David Hull’s and others’ attempts to provide full generalisation for selection processes, in order to show that sociocultural development and, particularly, scientific change can be considered as an instance of Darwinian selection. I argue that the recent work by Eileen Cornell Way on type hierarchies can offer the kind of generalisation needed to solve the main (...) problems that still affect Hull’s theory and to show that the evolutionary analogy is, after all, only a particular way of grouping phenomena together. If Hull’s main objective is a unified theory of selection, which supports the idea that science selection and natural selection obey the same laws, I also argue that the type hierarchy approach to models shows that this objective is unsustainable as it stands, and is in need of further development. I will firstly introduce the general outline of the type hierarchy approach to models. Then, after a brief recapitulation of Hull’s main points and difficulties, I will try and construct a hierarchy for a general abstraction of selection processes. Finally I will introduce the main criticisms that Hull’s work has faced from philosophers and scientists, and show how they compare with my proposal. (shrink)

Hildegard of Bingen was one of the most remarkable women of her day. From early childhood she experienced religious visions, and at the age of eight she entered a cloistered religious life in the Benedictine monastery of Disibondenberg. Eventually she not only became abbess of the community, but presided over the establishment of an important new convent near Bingen. All but forgotten for hundreds of years, Hildegard was rediscovered in the 1980s and since then her visionary writings have been widely (...) read and studied. Even more surprisingly, music that she composed has been performed and recorded to great acclaim. She has come to be seen by some as a proto-feminist icon -- a woman of great accomplishments who made her own way in a man's world and exerted extraordinary influence over some of the most powerful figures of her time. Much of Hildegard's correspondence has been preserved. It reveals that for more than 30 years this cloistered nun was an unflinching adviser and correspondent to all levels of church and society, from popes and kings to ordinary lay persons, from Jerusalem to England. With the 2004 OUP publication of Volume III of Joseph Baird and Radd Ehrman's translation, the complete correspondence became available for the first time in English. For this new abridgement, Baird has selected 75 of the most interesting and revealing of the letters from Volumes I, II, and III. Freed from the organizational restraints of the Latin edition of the letters, he has arranged them in roughly chronological order and provided greatly expanded, accessibly written introductory notes that contextualize the letters and explain their significance. As a result, this fascinating collection serves as a kind of life in letters that makes an ideal introduction ot this exceptional woman, her world, and her work. This book is the first to give a thorough and definitive illlumination of the personal life of Hildegard of Bingen as viewed through the defining lens of her personal correspondence: her early, hesitant bid for recognition of her spiritual gifts; her courageous, and ultimately futile, fight to retain the companionship of her close personal friend and the poignant outcome of that struggle; her vehement defiance of the male hierarchy in her bid to establish her own communities under her personal governance; her impudent challenge to contemporary conservatives views by the dress and customs she established in her community; her paean of praise for the power of music; and her adamant refusal, even at the advanced age of eighty, to give in to the demands of the male authorities even in the face of excommunication. (shrink)

Plant and animal species are information-processing entities of such complexity, integration, and adaptive competence that it may be scientifically fruitful to consider them intelligent. The possibility arises from the analogy between learning and evolution, and from recent developments in evolutionary science, psychology and cognitive science. Species are now described as spatiotemporally localized individuals in an expanded hierarchy of biological entities. Intentional and cognitive abilities are now ascribed to animal, human, and artificial intelligence systems that process information adaptively, and that (...) manifest problem-solving abilities. The structural and functional similarities between such systems and species are extensive, although they “are usually obscured by population-genetic metaphors that have nonetheless contributed much to our understanding of evolution.In this target article, I use Sewall Wright's notion of the “adaptive landscape” to compare the performances of evolving species to those of intelligent organisms. With regard to their adaptive achievements and the kinds of processes by which they are achieved, biological species compare very favorably to intelligent animals by virtue of interactions between populations and their environments, between ontogeny and phylogeny, and between natural, interdemic, organic, and species selection. Addressing the question of whether species are intelligent could help to refine our ideas about species, evolution, and intelligence, and could open new lines of empirical and theoretical inquiry in many disciplines. (shrink)

We study relations between measure-theoretic classes of ultrafilters, such as the Property M ultrafilters of [4], with other well-known ultrafilter classes. We define several classes of measure theoretic ultrafilters, of which the Property M ultrafilters are the strongest. We show which containments are provable in ZFC between these measure-theoretic ultrafilters and boolean combinations of well-known ultrafilters such as the selective, semi-selective, and P-point ultrafilters. We also list some of the containment results between measure-theoretic ultrafilters and several other ultrafilter classes, such (...) as the Arrow and Property C ultrafilters. (shrink)

For a number of years, the debate in evolutionary biology over the ’levels of selection’ has attracted intense interest from philosophers of science. The main question concerns the level of the biological hierarchy at which natural selection occurs. Does selection act on organisms, genes, groups, colonies, demes, species, or some combination of these? According to traditional Darwinian theory the answer is the organism -- it is the differential survival and reproduction of individual organisms that drives the (...) evolutionary process. But there are alternative views too, including pluralist views which say that the choice between different levels of selection is often a matter of perspective, not empirical fact. (shrink)

Authors frequently refer to gene-based selection in biological evolution, the reaction of the immune system to antigens, and operant learning as exemplifying selection processes in the same sense of this term. However, as obvious as this claim may seem on the surface, setting out an account of “selection” that is general enough to incorporate all three of these processes without becoming so general as to be vacuous is far from easy. In this target article, we set out (...) such a general account of selection to see how well it accommodates these very different sorts of selection. The three fundamental elements of this account are replication, variation, and environmental interaction. For selection to occur, these three processes must be related in a very specific way. In particular, replication must alternate with environmental interaction so that any changes that occur in replication are passed on differentially because of environmental interaction. One of the main differences among the three sorts of selection that we investigate concerns the role of organisms. In traditional biological evolution, organisms play a central role with respect to environmental interaction. Although environmental interaction can occur at other levels of the organizational hierarchy, organisms are the primary focus of environmental interaction. In the functioning of the immune system, organisms function as containers. The interactions that result in selection of antibodies during a lifetime are between entities (antibodies and antigens) contained within the organism. Resulting changes in the immune system of one organism are not passed on to later organisms. Nor are changes in operant behavior resulting from behavioral selection passed on to later organisms. But operant behavior is not contained in the organism because most of the interactions that lead to differential replication include parts of the world outside the organism. Changes in the organism's nervous system are the effects of those interactions. The role of genes also varies in these three systems. Biological evolution is gene-based (i.e., genes are the primary replicators). Genes play very different roles in operant behavior and the immune system. However, in all three systems, iteration is central. All three selection processes are also incredibly wasteful and inefficient. They can generate complexity and novelty primarily because they are so wasteful and inefficient. Key Words: evolution; immunology; interaction; operant behavior; operant learning; replication; selection; variation. (shrink)

Constructive Neutral Evolution is an evolutionary mechanism that can explain much molecular inter-dependence and organismal complexity without assuming positive selection favoring such dependency or complexity, either directly or as a byproduct of adaptation. It differs from but complements other non-selective explanations for complexity, such as genetic drift and the Zero Force Evolutionary Law, by being ratchet-like in character. With CNE, purifying selection maintains dependencies or complexities that were neutrally evolved. Preliminary treatments use it to explain specific genetic and (...) molecular structures or processes, such as retained gene duplications, the spliceosome, and RNA editing. Here we aim to expand the scope of such explanation beyond the molecular level, integrating CNE with Multi-Level Selection theory, and arguing that several popular higher-level selection scenarios are in fact instances of CNE. Suitably contextualized, CNE occurs at any level in the biological hierarchy at which natural selection as normally construed occurs. As examples, we focus on modularity in protein–protein interaction networks or “interactomes,” the origin of eukaryotic cells and the evolution of co-dependence in microbial communities—a variant of the “Black Queen Hypothesis” which we call the “Gray Queen Hypothesis”. (shrink)

According to the hierarchy of models account of scientific experimentation developed by Patrick Suppes and elaborated by Deborah Mayo, theoretical considerations about the phenomena of interest are involved in an experiment through theoretical models that in turn relate to experimental data through data models, via the linkage of experimental models. In this paper, I dispute the HoM account in the context of present-day high-energy physics experiments. I argue that even though the HoM account aims to characterize experimentation as a (...) model-based activity, it does not involve a modeling concept for the process of data acquisition, and it thus fails to provide a model-based characterization of the theory-experiment relationship underlying this process. In order to characterize the foregoing relationship, I propose the concept of a model of data acquisition and illustrate it in the case of the ATLAS experiment at CERN’s Large Hadron Collider, where the Higgs boson was discovered in 2012. I show that the process of data acquisition in the ATLAS experiment is performed according to a model of data acquisition that specifies and organizes the experimental procedures necessary to select the data according to a predetermined set of selection criteria. I also point out that this data acquisition model is theory-laden, in the sense that the underlying data selection criteria are determined by considering the testable predictions of the theoretical models that the ATLAS experiment is aimed to test. I take this sense of theory-ladenness to indicate that the relationship between the procedures of the ATLAS experiment and the theoretical models of the phenomena of interest is first established, prior to the formation of data models, through the data acquisition model of the experiment, thus not requiring the intermediary of other types of models as suggested by the HoM account. I therefore conclude that in the context of present-day HEP experiments, the HoM account does not consistently extend to the process of data acquisition so as to include models of data acquisition. (shrink)

Description of the biologicalhierarchy of the organism has been extendedhere to included the evolutionary andecological sub-hierarchies with theirrespective levels in order to give a completehierarchical description of life. These newdescriptions include direction of formation,types of constraints, and dual levels. Constraints are produced at the macromolecularlevel of genes/proteins, some of which (a) aredescendent restraints which hold a hierarchytogether and others (b) interact horizontallywith selective agents at corresponding levelsof the niche. The organism is a dual levelconstrained by both the ecologicalsub-hierarchy (survival) (...) and evolutionarysub-hierarchy (fitness) while serving as thehighest level of the specializationsub-hierarchy, therefore, it is unique inbelonging to three sub-hierarchies. Organismsexperience birth, sometimes death, andparticipate in evolution. Birth of an organismis realized when a cell is removed from theconstraints of the organism and assumes itsown organismal constraints. Death occurs withthe cessation of protein synthesis becauseproteins and their products constitutecomponents at high levels of the hierarchy. Selection is of two types, natural selection,involving adaptive traits interacting withfeatures in a niche, and hierarchicalselection, requiring traits to be compatiblewith existing hierarchical constraints. (shrink)

We review Evolution and the Levels of Selection by Samir Okasha. This important book provides a cohesive philosophical framework for understanding levels-of-selections problems in biology. Concerning evolutionary transitions, Okasha proposes that three stages characterize the shift from a lower level of selection to a higher one. We discuss the application of Okasha’s three-stage concept to the evolutionary transition from unicellularity to multicellularity in the volvocine green algae. Okasha’s concepts are a provocative step towards a more general understanding of (...) the major evolutionary transitions; however, the application of certain ideas to the volvocine model system is not straightforward. (shrink)

A monadic formula ψ is a selector for a monadic formula φ in a structure if ψ defines in a unique subset P of the domain and this P also satisfies φ in . If is a class of structures and φ is a selector for ψ in every , we say that φ is a selector for φ over .For a monadic formula φ and ordinals α≤ω1 and δ<ωω, we decide whether there exists a monadic formula ψ such that (...) for every Pα of order-type smaller than δ, ψ selects φ in . If so, we construct such a ψ.We introduce a criterion for a class of ordinals to have the property that every monadic formula φ has a selector over it. We deduce the existence of Sωω such that in the structure every formula has a selector.Given a monadic sentence π and a monadic formula φ, we decide whether φ has a selector over the class of countable ordinals satisfying π, and if so, construct one for it. (shrink)

Selectional preferences have a long history in both generative and computational linguistics. However, since the publication of Resnik's dissertation in 1993, a new approach has surfaced in the computational linguistics community. This new line of research combines knowledge represented in a pre‐defined semantic class hierarchy with statistical tools including information theory, statistical modeling, and Bayesian inference. These tools are used to learn selectional preferences from examples in a corpus. Instead of simple sets of semantic classes, selectional preferences are viewed (...) as probability distributions over various entities. We survey research that extends Resnik's initial work, discuss the strengths and weaknesses of each approach, and show how they together form a cohesive line of research. (shrink)

For principled and substantially philosophical reasons, based largely on his reform of natural history by inverting the Paleyan notion of overarching and purposeful beneficence in the construction of organisms, Darwin built his theory of selection at the single causal level of individual bodies engaged in unconscious struggle for their own reproductive success. But the central logic of the theory allows selection to work effectively on entities at several levels of a genealogical hierarchy, provided that they embody a (...) set of requisite features for defining evolutionary individuality. Genes, cell lineages, demes, species, and clades-as well as Darwin’s favoured organisms-embody these requisite features in enough cases to form important levels of selection in the history of life. R. A. Fisher explicitly recognized the unassailable logic of species selection, but denied that thsi real process could be important in evolution because, compared with the production of new organisms within a species, the origin of new species is so rare, and the number of species within most clades so low. I review this and other classical arguments against higher-level selection, and conclude that they are invalid in practice for interdemic selection, and false in principle for species selection. Punctuated equilibrium defines the individuality of species and refutes Fisher’s classical argument based on cycle time. In the second part of the paper, I argue that we have failed to appreciate the range and power of selection at levels above and below the organismic because we falsely extrapolate the defining properties of organisms to these other levels, and then regard the other levels as impotent because their effective individuals differ so much from organisms. We would better appreciate the power and generality of hierarchical models of selection if we grasped two key principles: first, that levels can interact in all modes, and not only in the negative style that, for heuristic and operational reasons, has received almost exclusive attention in the existing literature; and second, that each hierarchical level differs from all others in substantial and interesting ways, both in the style and frequency of patterns in change and causal modes. (shrink)

This dissertation considers the bases upon which ethical assessments of parental genetic trait selections for their children can be made. It argues that if parents engage in genetic trait selections, they must act to expand their child's range of open futures, not to constrict their child's range of open futures or to differentially shift their child's range of open futures. It contends that other proposed distinctions, including distinctions between normal and diseased states and between treatment selections and enhancement selections, do (...) not provide a sound basis for making ethical assessments of parental genetic trait selections. It contends that children have a right to an open future that parents hold in trust for their children and that parents must respect in making genetic trait selections.It considers examples of possible parental genetic trait selections regarding children's hearing, height and visual acuity. Finally, it addresses a number of concerns about and objections to this proposed basis for ethical assessment and to parental genetic trait selection generally but concludes that none of these concerns or objections are fatal the approach that if parents use parental genetic trait selection, they must do so in ways that expand their child's range of open futures. (shrink)

ABSTRACT As parents become increasingly able to make genetic trait selections on behalf of their children, they will need ethical guidance in deciding what genetic traits to select. Dena Davis has argued that parents act unethically if they make selections that constrain their child's range of futures. But some selections may expand the child's range of futures. And other selections may shift the child's range of futures, without either constraining or expanding that range. I contend that not only would (...) parents act unethically if they make selections that constrain the range of their child's futures, they would act unethically if they make selections that shift the range of their child's futures, because selections that shift the range of the child's futures would allow parents to over‐determine their child's futures. Thus, I contend that parents would act ethically only if they make selections that expand their child's range of futures. (shrink)

Traditional portfolio selection models mainly obtain the optimized portfolio ratio by focusing on the prices of financial products. However, investors’ multiple preferences and risk appetites are also significant factors that should be taken into account. In consideration of these two factors simultaneously, we propose a double-hierarchy model in this paper. Specifically, the first hierarchy quantifies investors’ risk appetite based on a historical simulation method and probabilistic preference theory. This hierarchy can be utilized to describe investors’ variable (...) risk appetites and ensure the obtained investment ratios meet investors’ immediate risk requirements. Then, using the cross-efficiency evaluation principle, the optimal investment ratios can be derived by fusing investors’ multiple preferences and risk appetites in the second hierarchy. Lastly, an illustrative example about evaluating the 10 largest capitalized stocks on the Shenzhen Stock Exchange is given to verify the feasibility and effectiveness of our newly proposed model. We make the theoretical contribution to improve the traditional portfolio selection model, especially considering investors’ subjective preferences and risk appetite. Moreover, the proposed model can be practical for assisting investors with their investment strategies in real life. (shrink)

Due to aging populations and the prolonging of working lives, the number of senior workers will increase. Therefore, this study investigates the use of SOC strategies across organizational levels as a means for senior workers to maintain workability and age successfully at work. The need to expand the perspective of the SOC model beyond the individual level, when applied to a work context, has been emphasized theoretically in the literature, nevertheless, SOC strategies have so far only been examined at the (...) individual level. This study is the first to explore SOC strategies at the organizational, leadership, and group level. We focus on senior employees and the SOC strategies they use to balance out demands and limited resources. Based on 23 semi-structured interviews with senior employees and immediate managers at two hospitals, and two dairies, we explore which specific SOC strategies are used at each level and reflect on the applicability of broadening the perspective of the SOC model when applying it to a work context. Based on the empirical findings and the discussion of the empirical exploration of SOC strategies beyond the individual level, we argue that it is advantageous to further pursue this line of inquiry and include the group, leadership, and organizational level when applying the SOC model in a work setting. (shrink)

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and (...) made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

With the continued expansion and commercialisation of fertility treatments, the selection and matching of donors have become more sophisticated and technologised. As part of this landscape, new form of genetic screening: ‘expanded carrier screening’ (ECS) is being offered as a technique to avoid the risk of donors passing on genetic conditions to future offspring. Allowing donors to be tested for hundreds of genetic conditions simultaneously, ECS marks a considerable departure from traditional ‘family history’ models of screening, which rely on (...) an individual's knowledge of family health. There is growing evidence of a drive towards the use of ECS within the fertility sector, and a growing number of clinics are offering it for a fee, as part of an egg or sperm donation cycle or as an add‐on to IVF treatment. In this article, we use methods of critical reflection to synthesise data from two studies to explore how ECS is being used to avoid genetic risk in IVF treatment using donor gametes. We suggest that ECS is a new form of repro‐genetic selection—a selective reproductive technology—with specific and important implications for donors, recipients and clinicians and with the potential to reconfigure the scope and application of gamete donation. We examine these implications and conclude that the existing policy blind spot relating to this development in fertility treatment practice needs to be urgently addressed. (shrink)

Managed care has brought wide-ranging changes to the health care system. Some of these changes have been well publicized. Among them are the financial pressures that have resulted in numerous mergers of health care institutions, the restriction on the ability of patients to select their physician of choice, and the ever diminishing number of days that patients are permitted to stay in the hospital. Individual physicians, too, have been affected. For example, they are under pressure to see more patients per (...) unit time and to use fewer resources. Utilization review and payment methods may make them reluctant to undertake the full set of diagnostic tests and therapeutic interventions when they might otherwise have done so. (shrink)

This paper expands on, and provides a qualified defence of, Arthur Fine’s selective interactions solution to the measurement problem. Fine’s approach must be understood against the background of the insolubility proof of the quantum measurement. I first defend the proof as an appropriate formal representation of the quantum measurement problem. Then I clarify the nature of selective interactions, and more generally selections, and I go on to offer three arguments in their favour. First, selections provide the only known solution to (...) the measurement problem that does not relinquish any of the premises of the insolubility proofs. Second, unlike some no-collapse interpretations of quantum mechanics selections suffer no difficulties with non-ideal measurements. Third, unlike most collapse-interpretations selections can be independently motivated by an appeal to quantum dispositions. (shrink)

In this paper we focus on the modularity of visual functions in the human visual cortex, that is, the specific problems that the visual system must solve in order to achieve recognition of objects and visual space. The computational theory of early visual functions is briefly reviewed and is then used as a basis for suggesting computational constraints on the higher-level visual computations. The remainder of the paper presents neurological evidence for the existence of two visual systems in man, one (...) specialized for spatial vision and the other for object vision. We show further clinical evidence for the computational hypothesis that these two systems consist of several visual modules, some of which can be isolated on the basis of specific visual deficts which occur after lesions to selected areas in the visually responsive brain. We will provide examples of visual modules which solve information processing tasks that are mediated by specific anatomic areas. We will show that the clinical data from behavioral studies of monkeys (Ungerleider and Mishkin 1984) supports the distinction between two visual systems in monkeys, the 'what' system, involved in object vision, and the 'where' system, involved in spatial vision. (shrink)

This paper expands on, and provides a qualified defence of, Arthur Fine's selective interactions solution to the measurement problem. Fine's approach must be understood against the background of the insolubility proof of the quantum measurement. I first defend the proof as an appropriate formal representation of the quantum measurement problem. The nature of selective interactions, and more generally selections, is then clarified, and three arguments in their favour are offered. First, selections provide the only known solution to the measurement problem (...) that does not relinquish any of the explicit premises of the insolubility proofs. Second, unlike some no-collapse interpretations of quantum mechanics, selections suffer no difficulties with non-ideal measurements. Third, unlike most collapse interpretations, selections can be independently motivated by an appeal to quantum propensities. IntroductionThe problem of quantum measurement2.1 The ignorance interpretation of mixtures2.2 The eigenstate–eigenvalue link2.3 The quantum theory of measurementThe insolubility proof of the quantum measurement3.1 Some notation3.2 The transfer of probability condition (TPC)3.3 The occurrence of outcomes condition (OOC)A defence of the insolubility proof4.1 Stein's critique4.2 Ignorance is not required4.3 The problem of quantum measurement is an idealisationSelections5.1 Representing dispositional properties5.2 Selections solve the measurement problem5.3 Selections and ignoranceNon-ideal selections6.1 No-collapse interpretations and non-ideal measurements6.2 Exact and approximate measurements6.3 Selections for non-ideal interactions6.4 Approximate selections6.5 Implications for ignoranceSelective interactions test quantum propensities7.1 Equivalence classes as physical ‘aspects’: a critique7.2 Quantum dispositions7.3 Selections as a propensity modal interpretation7.4 A comparison with Popper's propensity interpretation. (shrink)

Hierarchical expansions of the theory of natural selection exist in two distinct bodies of thought in evolutionary biology, the group selection and the species selection traditions. Both traditions share the point of view that the principles of natural selection apply at levels of biological organization above the level of the individual organism. This leads them both to considermultilevel selection situations, where selection is occurring simultaneously at more than one level. Impeding unification of the theoretical (...) approaches of the multilevel selection traditions are the different goals of investigators in the different subdisciplines and the different types of data potentially available for analysis. We identify two alternative approaches to multilevel situations, which we termmultilevel selection [1] andmultilevel selection [2]. Of interest in the former case are the effects of group membership onindividual fitnesses, and in the latter the tendencies for the groups themselves to go extinct or to found new groups (i.e., group fitnesses). We argue that: neither represents the entire multilevel selection process; both are aspects of any multilevel selection situation; and both are legitimate approaches, suitable for answering different questions. Using this formalism, we show that: multilevel selection [2] does not require emergent group properties in order to provide an explanatory mechanism of evolutionary change; multilevel selection [1] is usually more appropriate for neontological group selection studies; and species selection is most fruitfully considered from the point of view of multilevel selection [2]. Finally we argue that the effect hypothesis of macroevolution, requiring, in selection among species, both the absence of group effects on organismic fitness (multilevel selection [1]), and the direct determination of species fitnesses by those of organisms, is untestable with paleontological data. Furthermore, the conditions for the effect hypothesis to hold are extremely restrictive and unlikely to apply to the vast majority of situations encountered in nature. (shrink)

A number of animal species from different lineages live socially. One of the features of social living is the formation of dominance hierarchy. Despite its obvious benefit in the survival probability of the species, the hierarchical structureitself poses psychological and physiological burden leading to the chronic activation of stress related pathways. Considering these apparently conflicting observations, here we propose that social hierarchy can act as a selective force in the evolution of social species. We also discuss its role (...) on social psychology. (shrink)

This study focuses on the application of multicriteria decision-making techniques, specifically the analytic hierarchy process (AHP), to identify corporate socialresponsibility information which both companies and stakeholders consider relevant and material. This work explains how the AHP methodology was applied in the selection of material indicators in corporate social responsibility reporting, the interpretation of these indicators and their relative importance. The results of this study are summarized in 60 indicators distributed in four areas: environment, economy, corporate governance and social. (...) As this last area contains the greatest number of indicators, it was divided into four sub-areas (human resources, human rights, product responsibility and society). (shrink)

What if someone asked you to keep a four-kilometer-long ruler absolutely still so that you could measure deformations of length of ~1x10^-18m using light? On September 14, 2015, physicists and engineers at the Laser Interferometer Gravitational-Wave Observatory (LIGO) accomplished this absurd feat when they first detected gravitational wave signals—the result of the most violent events in our universe, such as the collision of two black holes—using two immense L-shaped instruments with arms four-kilometers in length and placed in what seemed to (...) be the middle of nowhere. -/- The focus of this dissertation centers on how scientists must have an intricate understanding of the environment surrounding LIGO’s instruments to understand the vast and active universe through the detection of gravitational waves. I explore how LIGO physicists and engineers constructed stillness to distinguish the surrounding natural and built environment from gravitational wave signals. I explore how the pre-LIGO and LIGO laboratory spaces became an expanded laboratory extending as an overlay into the surrounding environment and beyond. I show that the metes and bounds of the expanded laboratory are defined by what the interferometers are sensitive to. I further explore how physicists, engineers, and data scientists theorized an experiment that required such an extreme sensitivity (i.e., imagining stillness), developed methods to investigate, understand, and abate noise, disturbances, and aberrations (i.e., engineering stillness), found sites with minimal noise profiles, both physical and social, that would accommodate the size and function of the instruments despite land uses in conflict with the experiment (i.e., finding stillness), and understood the overlapping human and non-human uses of the land that jeopardized the ability to make these highly precise detections and mediate solutions that would allow for concurrent use of the land (i.e., negotiating stillness). -/- Through this history, I conclude that the level of sensitivity the physicists and engineers can attain in the LIGO interferometers is predicated on constructed stillness. This determines the instruments’ ability to measure the minute deformations in length caused by gravitational waves such that the physicists, engineers, and data scientists can rule out the geography of noise and make the claim that the heterogeneity of their locations at Hanford and Livingston does not negate their assertion of twin detections of gravitational wave signals across their two sites. (shrink)

Expanded universal carrier screening (EUCS) entails a population‐wide screening offer for multiple disease‐causing mutations simultaneously. Although there is much debate about the conditions under which EUCS can responsibly be introduced, there seems to be little discussion about its aim: providing carrier couples with options for autonomous reproductive choice. While this links in with current accounts of the aim of foetal anomaly screening, it is different from how the aim of ancestry‐based carrier screening has traditionally been understood: reducing the disease burden (...) in the population. The reasons why the aim of EUCS is presented in terms of ‘autonomy’ rather than ‘prevention’ have not been spelled out in the literature. This paper seeks to fill this gap by considering the morally relevant similarities and dissimilarities between foetal anomaly screening, ancestry‐based carrier screening and EUCS. When carrier screening is performed in the prenatal period, enhancing autonomy appears the most appropriate aim of EUCS, as the alternative of ‘prevention through selective abortion’ would urge women to terminate wanted pregnancies. However, when screening is conducted in the preconception period, carrier couples can avoid the birth of affected children by other means than selective abortion, for instance preimplantation genetic diagnosis. To the extent that this increased control over passing on a genetic disorder raises questions of parental responsibility, it seems necessary that the account of the aims of EUCS is wider than only in terms of enhancing reproductive autonomy. (shrink)

THE AIM OF THE VOLUME IS TO INTRODUCE STUDENTS TO THE PHILOSOPHY OF RELIGION BY ACQUAINTING THEM WITH THE WRITINGS OF SOME OF THE THINKERS WHO HAVE MADE SUBSTANTIAL CONTRIBUTIONS IN THIS AREA. THIS NEW EDITION EXPANDS THE RANGE OF TOPICS BY INCLUDING AN ENTIRELY NEW CHAPTER ON DEATH AND IMMORTALITY AND A NEW SUBSECTION ON THE MORAL ARGUMENT. THERE IS ALSO SOME NEW MATERIAL ON WITTGENSTEIN AND FIDEISM, RELIGIOUS PLURALISM, AND FAITH AND THE NEED FOR EVIDENCE. ALMOST EVERY CHAPTER (...) HAS BEEN CHANGED BY DELETIONS OR ADDITIONS TO UPDATE THE SELECTIONS AND PROVIDE MORE MATERIAL THAT IS UNDERSTANDABLE TO BEGINNING STUDENTS. (shrink)

In a series of articles and in a recent book, What Darwin Got Wrong, Jerry Fodor has objected to Darwin’s principle of natural selection on the grounds that it assumes nature has intentions.1 Despite the near universal rejection of Fodor’s argument by biologists and philosophers of biology (myself included),2 I now believe he was almost right. I will show this through a historical examination of a principle that Darwin thought as important as natural selection, his principle of divergence. (...) The principle was designed to explain a phenomenon obvious to any observer of nature, namely, that animals and plants form a hierarchy of clusters. Theodosius Dobzhansky made this the motivating observation of his great synthesizing work, Genetics and the Origin of Species (1937): “the living world is not a single array of individuals in which any two variants are connected by a series of intergrades, but an array of more or less distinctly separate arrays, intermediates between which are absent or at least rare. . . Small.. (shrink)

Expanded universal carrier screening (EUCS) entails a population‐wide screening offer for multiple disease‐causing mutations simultaneously. Although there is much debate about the conditions under which EUCS can responsibly be introduced, there seems to be little discussion about its aim: providing carrier couples with options for autonomous reproductive choice. While this links in with current accounts of the aim of foetal anomaly screening, it is different from how the aim of ancestry‐based carrier screening has traditionally been understood: reducing the disease burden (...) in the population. The reasons why the aim of EUCS is presented in terms of ‘autonomy’ rather than ‘prevention’ have not been spelled out in the literature. This paper seeks to fill this gap by considering the morally relevant similarities and dissimilarities between foetal anomaly screening, ancestry‐based carrier screening and EUCS. When carrier screening is performed in the prenatal period, enhancing autonomy appears the most appropriate aim of EUCS, as the alternative of ‘prevention through selective abortion’ would urge women to terminate wanted pregnancies. However, when screening is conducted in the preconception period, carrier couples can avoid the birth of affected children by other means than selective abortion, for instance preimplantation genetic diagnosis. To the extent that this increased control over passing on a genetic disorder raises questions of parental responsibility, it seems necessary that the account of the aims of EUCS is wider than only in terms of enhancing reproductive autonomy. (shrink)

Game theory has played a critical role in elucidating the evolutionary origins of social behavior. Sober and Wilson model altruism as a prisoner's dilemma and claim that this model indicates that altruism arose from group selection pressures. Sober and Wilson also suggest that the prisoner's dilemma model can be used to characterize punishment; hence, punishment too originated from group selection pressures. However, empirical evidence suggests that a group selection model of the origins of altruistic punishment may be (...) insufficient. I argue that examining dominance hierarchies and coalition formation in chimpanzee societies suggests that the origins of altruistic punishment may be best captured by individual selection models. I suggest that this shows the necessity of coupling of game-theoretic models with a conception of what our actual social structure may have been like to best model the origins of our own behavior. ‡I would like to thank Zachary Ernst and Emma Marris for their many helpful comments which greatly improved this paper. †To contact the author, please write to: Department of Philosophy, University of Maryland, Skinner Building, College Park, MD 20742; e-mail: [email protected]. (shrink)

The aim of this paper is to point out a hermeneutic gap in Assemblies of God – Back to God’s order of service where 1 Corinthians 14:26–32 is read, eschewing verses 33–38. It points out the Assemblies of God’s perception of women’s ordination into the ministry, where women are allowed to participate in public worship but are not allowed to take up the pastoral leadership of the local assembly. The research problem is the hermeneutic gap behind refusal to ordain women (...) into the ministry. The selective reading of the Scriptures poses a problem for hermeneutical inclusiveness that embraces social exegesis to arrive at the conclusion that it is not unscriptural to ordain women into pastoral leadership. The conclusion gives the remedial actions of the scenario, to suggest breaking out of a shell, agency and resilience, engaging social exegesis and hermeneutics, and engaging the community through dialogue to justify the rationale for ordaining women into the pastoral ministry in the same par with men.Contribution: Situated within feminist theology, the study on women pastoral leadership is a burning issue for both classical Pentecostals and some of their evangelical counterparts. Pentecostal and charismatic studies should expand their understanding of Pauline theology regarding women’s leadership to arrive at inclusiveness and non-sexism. (shrink)

Glutamine repeat expansion has been established as the mutation underlying five inherited neurodegenerative diseases. The mechanism by which this apparently universal mutation, in ubiquitously expressed proteins, causes highly selective neurodegeneration is unknown. The proteins containing the glutamine expansions are otherwise unrelated and likely to have different functions. Two recently published papers(1,2) provide evidence of a conformational change occurring in polyglutamine expansions, which may allow novel interactions and is consistent with a toxic gain‐of‐function hypothesis. HAP1, a protein that interacts with huntingtin (...) (Huntington's disease protein), has an expression profile that intriguingly mirrors the selective neurodegeneration seen in Huntington's disease(2). (shrink)

In the years that have passed since publication of the Club of Rome's seminal report "Limits to Growth," the issues raised in terms of development, resource use and the environment have become ever more pressing. The potential of advances in science and technology to affect all aspects of life, including development, was then little understood. Today's unparalleled burst in scientific and technological creativity has given new options and opportunities to the world economic system. Central to this process is a series (...) of concepts which includes the scientification of technology, by which technology is increasingly generated and developed on scientific bases, the breaking down of interdisciplinary barriers and mankind's new found capacity literally to invent resources, leading to the emergence of whole categories of new materials. These changes make possible a new approach to economic growth, relying on decentralization and flexibility and the selection of technology mixes best suited to different socio-economic and cultural contexts. In parallel, the key importance above all of the information technologies is producing a dematerialization of goods, a trend exemplified by the shift from product oriented to function oriented industries. The new technologies of the 1980s are cross-fertilizing and self-disseminative. They are creating an exceptional number of innovative options in processes, products, services, organization and markets. Mature industrial sectors can undergo a process of rejuvenation to recover competitiveness by the grafting of advanced technologies onto traditional activities. The results are already evident in industrialized countries, such as Italy. The flexibility offered by the new technologies offers perhaps our best hope for a solution to the widening gap between rich and poor nations, contrary to the belief that identifies in advances in science and technology the seeds of a process of polarization dividing the world. The countries of the United States, Japan and Western Europe--the so-called Triad Power--dominate the emerging technologies and their applications. In fact, given the pace of today's technological revolution, developing countries are effectively excluded from active participation in the process of technological change. New technologies are not "off the peg," they have to be learned and controlled, to be introduced into an existing flexible system possessing trained manpower and an adequate capital base. Introduction into the Third World, where these essential conditions are frequently lacking, will not be a painless process. Technology transfer without adaptation is likely to have undesirable cultural and societal disadvantages. North and South are simultaneously experiencing radically different processes of evolution: the former, through restructuring and innovation; the latter, through the drive for more quantitative growth. Continuing stress on quantitative growth carries with it the risk that other goals--environmental quality, even the eradication of poverty--may suffer. Here lies the possibility that unless economic patterns change, today's imbalance between the haves and the have nots may be perpetuated or even consolidated. The countries of the North individually all face problems in addressing these issues. The international banking system is hamstrung with the problems of Third World debt. Primary producers no longer command high prices for their raw materials on world markets and so this source of development funding is also drying up. The need is therefore for a global approach. In each Third World situation, specific needs and requirements must be identified to be tackled via technology blending, whereby a mix of emerging and traditional technologies is selected to raise the quality of output to the levels now demanded by a sophisticated world economy. Another important area is that of energy, together with the worsening environmental and even climatic effects of energy policies. The need is for a long term strategic view to marshall the contribution new technologies can make to improving the lot of mankind in full respect for his environment. Technological change also implies societal change. In labor markets, labor mismatch creates pockets of employment which are difficult to eradicate. Yet, overall, the hope is that expanding economic horizons will create unlimited opportunities for new jobs and new skills. The key is education and training. A feed and feedback mechanism between education and the economy represents an intangible investment in the future. Economic growth, technological innovation, development of culture and society, have always moved together with synergism. Current changes are not so much just physical as conceptual. We are passing from a mechanical (or mechanistic) society to one that can be termed cybernetic. Causality, sequentiality and hierarchy are giving way to a functional interdependence at a systems level. Greater participation will produce more opportunities for self-fulfillment. As old social equilibria collapse, management of social change can be seen to be as important as management of technological change. The technological revolution has deep roots in Western culture. It is a liberating force that can lead to greater cultural enrichment. By understanding the changes now underway, we can ensure that the new pattern of society that emerges from exploitation of the new technologies retains man at its center and so benefits the whole of humanity. (shrink)

This anthology includes 42 selections from a wide variety of cultural backgrounds and historical periods. The text is not limited to Western material; it also includes Native American, African-American, Hispanic and feminist selections. While quite diverse historically and culturally, the readings are chosen for their readability and philosophical significance. To facilitate incorporation into existing courses, the selections are arranged in six chapters that correspond to traditional philosophical categories: self identity, knowledge and truth, creation and reality, ethics, politics and religion.

Accounts of mechanistic explanation, especially as applied to biology and sometimes going under the heading of “new mechanism,” provided an attractive alternative to nomological accounts that preceded them. These accounts were motivated by selected examples, drawn primarily from cell and molecular biology and neuroscience. However, the range of examples that scientists take to be mechanistic explanations is far broader. We focus on examples that differ from those traditionally recruited by Mechanists. Our contention is that attention to additional examples will lead (...) to a richer conception of mechanistic explanation, prompting a shift from what we refer to as Mechanism 1.0 to Mechanism 2.0. (shrink)

In a unique collection of essays and poems written in English, French, German and Russian (with a seasoning of Greek and Japanese), Constantine Shapiro explores fascinating universal questions and connections. Why, he asks, do so many people feel unhappy? Why do so many go to the doctor? Why is there so much criminality? Why is there international unrest? What is a healthy soul? In his investigation of these and other "Big Questions," the author examines such disparate areas as Japanese kanji (...) ideograms and personal character, spiritual ontology and science, Zeus and Christianity, objectivity and subjectivity in time and space, the nature of experience, and the flow of consciousness. The modern reader will find much to ponder in this second, expanded edition of Selected Writings. Also included are facsimiles of the typescript of Two Mathematical Problems and the Japanese translation of Transzendentale Musiklehre. (shrink)

We give a sufficient condition for a countable model M of PA to be expandable to an ω-model of AST with absolute Ω-orderings. The condition is in terms of saturation schemes or, equivalently, in terms of the ability of the model to code sequences which have some kind of definition in (M, ω). We also show that a weaker scheme of saturation leads to the existence of wellorderings of the model with nice properties. Finally, we answer affirmatively the question of (...) whether the intersection of all β-expansions of a β-expandable model M is the set RA(M, ω)--the ramified analytical hierarchy over (M, ω). The results are based on forcing constructions. (shrink)

The studies of mysticism have traditionally emphasized a common core centered around experiences of ego dissolution and unity. However, this focus on a central set of experiences tends to downplay the non-central aspects, resulting in a limited understanding that may not encompass many other types of extraordinary experiences. This article proposes a layered hierarchy model of mysticism, which reverts to the fundamental definition of mysticism and resonates with the Jamesian characteristics of mysticism as noetic and ineffable. Consequently, an extended (...) definition is put forth to characterize mysticism as the transcendence of perceived reality and the transformation of the perceiver. Within this proposed model, four layers of mysticism are delineated. Monistic Mysticism is characterized by the perception of oneness in all existence and the dissolution of selfhood, exemplified by perennialist mystical unity. Nondualistic Mysticism involves the recognition of a higher reality beyond the mundane world and the subjugation of the ego to an idealized divine, exemplified by religious experiences. Dualistic Mysticism encompasses a world of spirits in contrast to human reality, where the self detaches from and interacts with spiritual beings, exemplified by psychedelic experiences and spiritism. Pluralistic Mysticism entails numerous coexisting realities, and the self is understood to have many facets and boundless potentials, exemplified by psychic phenomena and non-physicalism. This expanded framework broadens the scope of mysticism and makes it a versatile tool for studying a wide range of human experiences under a unified framework. (shrink)

As biomedical research with volunteers was expanded in the United States, the rule of subject selection, constituting scientific and ethical criteria, was generated in 1981 to resolve selection bias in research. Few historical studies, however, have investigated the role of this new hybrid rule in institutional review systems. This paper describes how bioethics commissions and federal agencies have created the subject selection rule based on the concept of justice. I argue that the standardization of this rule as (...) temporal measures, linked with risk-benefit assessment, has reformed the review mechanism, specifically investigators’ modification of research plans, thereby developing justice as balancing. (shrink)

Life goals or aspirations can be distinguished as intrinsic or extrinsic, with different implications for well-being. In this study we used network analysis to reexamine this intrinsic-extrinsic distinction, illustrating how novel candidate aspirations can be mapped along this dimension using innovative methods. We identify four previously unexamined life aspirations, predicting that aspiring for power and social adherence would group with extrinsic goals, whereas aspiring for self-expression and mastery would group with intrinsic goals. In two samples (n = 196; n = (...) 346) we analyze both the original life-goal variables and these novel aspirations using factor analysis, multidimensional scaling, circumplex modeling, and a network analysis using a graphical least absolute shrinkage and selection operator (glasso) to estimate the network structure of aspirations using EBIC. Replicating past intrinsic-extrinsic distinctions, all four methods further classified power and social adherence as extrinsic goals, and self-expression and mastery as intrinsic goals. The intrinsic-extrinsic distinction was also clearly visible in the network analysis. Finally, consistent with hypotheses, power and social adherence were unrelated to wellness indicators, whereas self-expression and mastery correlated positively with well-being indicators and negatively with ill-being indicators, supporting their hypothesized nature as extrinsic and intrinsic, respectively. (shrink)

Personality traits describe dispositions influencing individuals' behavior and performance at work. However, in the context of personnel selection, the use of personality measures has continuously been questioned. To date, research in selection settings has focused uniquely on predicting task performance, missing the opportunity to exploit the potential of personality traits to predict non-task performance. Further, personality is often measured with self-report inventories, which are susceptible to self-distortion. Addressing these gaps, the planned study seeks to design new personality measures (...) to be used in the selection context to predict a wide range of performance criteria. Specifically, we will develop a situational judgment test and a behavior description interview, both assessing Big Five personality traits and Honesty-Humility to systematically compare these new measures with traditional self-report inventories regarding their criterion-related validity to predict four performance criteria: task performance, adaptive performance, organizational citizenship behavior, and counterproductive work behavior. Data will be collected in a simulated selection procedure. Based on power analyses, we aim for 200 employed study participants, who will allow us to contact their supervisors to gather criterion data. The results of this study will shed light on the suitability of different personality measures to predict an expanded range of performance criteria. (shrink)

Evidence-Based Medicine has little consideration for mechanisms and philosophers of science and medicine have recently made pleas to increase the place of mechanisms in the medical evidence hierarchy. However, in this debate the notions of mechanisms seem to be limited to 'mechanistic processes' and 'complex-systems mechanisms,' understood as 'componential causal systems'. I believe that this will not do full justice to how mechanisms are used in biological, psychological and social sciences and, consequently, in a more biopsychosocial approach to medicine. (...) Here, I propose, following (Kuorikoski, 2009), to pay more attention to 'abstract forms of interaction' mechanisms. The present work scrutinized review articles on depression and medically unexplained pain, which are considered to be of multifactorial pathogenesis, for their use of mechanisms. In review articles on these disorders there seemed to be a range of uses between more 'abstract forms of interaction' and 'componential causal system' mechanisms. I therefore propose to expand the notions of mechanisms considered in medicine to include that of more 'abstract forms of interaction' to better explain and manage biopsychosocial disorders. (shrink)

In the early 2000s, the development of local food systems in advanced industrial countries has expanded beyond creation and support of farmers’ markets and community supported agriculture farms and projects to include targeted Buy Local Food campaigns. Non-governmental groups in many U.S. places and regions have launched such campaigns with the intent of motivating and directing consumers toward more local food purchasing in general. This article examines the current manifestations and possibilities for social justice concerns in Buy Local Food campaigns, (...) by considering them within the more general category of “selective patronage“ campaigns. Historical campaign examples, such as Buy Union, Buy American, and Buy Black campaigns, offer instructive comparisons to contemporary consumer campaigns promoting local food. Through examining the construction of threats, intended beneficiaries, products to be avoided, and those to be preferentially selected, the paper demonstrates how selective patronage campaigns have emphasized social justice needs and concerns for designated groups in ways that have been potentially exclusionary of other disadvantaged groups and thus undermining of social justice more broadly. As a contemporary instance of “selective patronage,“ Buy Local Food campaigns exhibit similar contradictory impulses, which are intensified by the conceptual and practical pitfalls in designating “local.“ The article concludes by considering how the challenges and prospects for commitments to social justice in local food consumer campaigns reinforce the importance of emerging initiatives centered on domestic fair trade. (shrink)