This chapter provides a brief overview of the history of behavioral neurology, dividing it roughly into six eras. In the ancient and classical eras, emphasis is placed on two transitions: firstly, from descriptions of head trauma and attempted neurosurgical treatments to the exploratory dissections during the Hellenistic period and the replacement of cardiocentrism; and secondly, to the more systematic investigations of Galenus and the rise of pneumatic ventricular theory. In the medieval through post-Renaissance eras, the scholastic consolidation of knowledge and (...) the role of compendia are emphasized, along with the use of new methods from within a mechanistic framework. With the discovery of electrical conductance and the rise of experimentalism, we frame the modern era as period of intense debate over localization, decomposition, and other mechanistic principles, and marked by rapid discovery about the brain. The chapter ends with a discussion of the contemporary era, focusing on the establishment of behavioral neurology research on aphasia, apraxia, and neuropsychiatric conditions. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Neurology of Culture, or How We Move From Rage to Ritual in the Process of HominizationGregory J. Lobo (bio)The most (or rather the only) effective form of reconciliation—that would stop this crisis, and save the community from total self-destruction—is the convergence of all collective anger and rage towards a random victim, a scapegoat, designated by mimetism itself, and unanimously adopted as such.—René Girard, Evolution and Conversion, 64.INTRODUCTIONHow do (...) we move from rage to ritual? How do we become human? The work of René Girard would seem to offer an answer to this question. In this brief essay I want to simply add some evolutionary and neuroscientific details to Girard's theory, which flesh out while also corroborating the basic components of it. [End Page 255]To do this I need to draw a distinction between religion and culture. I mention this from the outset because the main source upon which I draw to represent Girard's thinking is the book Evolution and Conversion. Dialogues on the Origins of Culture, with Pierpaolo Antonello and João Cezar de Castro Rocha, published in 2008. I use this particular source because, as Girard's interlocutors say in their foreword to it, this book "is intended as a reassessment of Things Hidden since the Foundation of the World, 30 years on,"1 and it evidences the "ways in which, over 30 years, mimetic theory has matured, and its fruitfulness become more apparent, even since the initial excitement of Girard's groundbreaking works in the 1970s."2 I highlight my need to distinguish between culture and religion due to the fact that in Evolution and Conversion Antonello and Castro Rocha state forthrightly that for Girard (and, one might presume, for Girardians), culture and religion "amount to the same thing."3 But it is not totally clear that this holds. For as Girard, in the same book, says, "religion, as an institution, comes into being through the scapegoat mechanism."4 Thus, the question arises as to what it is that allows humans to have institutions in the first place. Surely the answer is the capacity for culture as such, understood as the very capacity for symbolic thought, for the manipulation of mental images and their combination into new ones. Hopefully, in the discussion that follows, my insistence on the need to analytically distinguish between culture and religion will be born out. For now, I simply ask the reader to play along. If the reader is game, I can restate my purpose: What is the neurology of culture, such that we can become human, or move from blind rage to deliberate ritual?THE MIMETIC MECHANISMGirard, we should recall, insists that we start "from a purely naturalistic standpoint."5 With this injunction in mind, I will give an account of the "mimetic mechanism," an expression that "describes the whole process, beginning with mimetic desire, which then becomes mimetic rivalry, eventually escalating to the stage of a mimetic crisis and finally ending with the scapegoat resolution"6 that strives for naturalistic representation. Therefore, I will avoid terms like "community" or even "group," which already suggest the existence of something like cultural realities. A naturalistic standpoint, which I take to be a scientific standpoint, must strive to circumvent begging the question by using terms like these, for they refer exactly to the phenomena we are trying to explain: a self-conscious sense of belonging and community. [End Page 256]For those familiar enough with its presuppositions about the human nature that underlies, or is the foundation of, human culture, the mimetic mechanism can be presented in a somewhat straightforward fashion. This presentation relies on Chapter 2 of Evolution and Conversion.The desire of Homo sapiens is in essence mimetic. That is, an individual member of the species desires what its proximal conspecifics—its models—desire. That two conspecifics should desire the same thing leads, inevitably, to two intermediate outcomes. First, the desire for what the other desires intensifies, due to the effects of mimesis; second, this drives the two now mutual models almost inevitably into conflict, as they become doubles. This is conflictual mimesis. The conflict can turn violent and... (shrink)

The topic of mechanistic explanation in neuroscience has been a subject of recent discussion. There is a lot of interest in understanding what these explanations involve. Furthermore, there is disagreement about whether neurological mechanisms themselves should be viewed as reductionist in nature. In this paper I will explain how these two issues are related. I will, first, describe how mechanisms support a form of antireductionism. This is because the mechanisms that exist should be seen as involving part-whole relations, where (...) the behavior of a whole is more than the sum of its parts. After this, I will consider mechanistic explanations and how they can be understood. While some people think the explanations concern existing entities in the world, I will argue that we can understand the explanations by viewing them in terms of arguments. Despite the fact that it is possible to understand mechanistic explanations in this manner, the antireductionist point remains. (shrink)

A fundamental goal of research in neuroscience is to uncover the causal structure of the brain. This focus on causation makes sense, because causal information can provide explanations of brain function and identify reliable targets with which to understand cognitive function and prevent or change neurological conditions and psychiatric disorders. In this research, one of the most frequently used causal concepts is ‘mechanism’ — this is seen in the literature and language of the field, in grant and funding (...) inquiries that specify what research is supported, and in journal guidelines on which contributions are considered for publication. In these contexts, mechanisms are commonly tied to expressions of the main aims of the field and cited as the ‘fundamental’, ‘foundational’ and/or ‘basic’ unit for understanding the brain. Despite its common usage and perceived importance, mechanism is used in different ways that are rarely distinguished. Given that this concept is defined in different ways throughout the field — and that there is often no clarification of which definition is intended — there remains a marked ambiguity about the fundamental goals, orientation and principles of the field. Here we provide an overview of causation and mechanism from the perspectives of neuroscience and philosophy of science, in order to address these challenges. (shrink)

One of the traditional views of self-deception has been in terms of a dynamically-driven defense mechanism which is employed in order to enhance self-esteem by denying contradictory evidence. Denial is evident during stressful events in everyday life, as well as in cases of mental and somatic impairments. A detailed analysis of a specific neurological syndrome, prosopagnosia, where covert recognition of familiar faces may coexist with lack of overt recognition, demonstrates the inapplicability of the dynamic interpretation of self-deception in (...) terms of denial to some neurological syndromes, and the usefulness of a new conceptualization of this process in terms of dissociation between modular and central processes. It is proposed that self-deception be considered a complex process which may be conceived of as a defense mechanism in everyday life, and as a product of functional dissociation in neurological syndromes. (shrink)

Piccinini and Craver (Synthese 183:283–311, 2011) argue for the surprising view that psychological explanation, properly understood, is a species of mechanistic explanation. This contrasts with the ‘received view’ (due, primarily, to Cummins and Fodor) which maintains a sharp distinction between psychological explanation and mechanistic explanation. The former is typically construed as functional analysis, the analysis of some psychological capacity into an organized series of subcapacities without specifying any of the structural features that underlie the explanandum capacity. The latter idea, of (...) course, sees explanation as a matter of describing structures that maintain (or produce) the explanandum capacity. In this paper, I defend the received view by criticizing Piccinini and Craver’s argument for the claim that psychological explanation is not distinct from mechanistic explanation, and by showing how psychological explanations can possess explanatory force even when nothing is known about the underlying neurological details. I conclude with a few brief criticisms about the enterprise of mechanistic explanation in general. (shrink)

The master-module theory of consciousness is considered in the light of experimental evidence that has emerged since the model was first published. It is found that these new results tend to strengthen the original hypothesis. It is also argued that the master module is involved in generation of the schemata previously postulated to be associated with consciousness . The recent discovery of attention-related activity in the thalamic intralaminar nuclei is taken to indicate that these structures constitute an important part of (...) the feedback loop which the theory conjectured to mediate thought. The theory is shown to lead to a remarkably simple rationalization of the cerebral cortex, and it offers explanations of attention, binocular rivalry and qualia. It also makes the surprising prediction that Broca's area might not exclusively serve speech. (shrink)

Many experimental philosophers are philosophers by training and professional affiliation, but some best work in experimental philosophy has been done by people who do not have advanced degrees in philosophy and do not teach in philosophy departments. This chapter explains that the experimental philosophy is the empirical investigation of philosophical intuitions, the factors that affect them, and the psychological and neurological mechanisms that underlie them. It explores what are philosophical intuitions, and why do experimental philosophers want to study them (...) using the methods of empirical science. The positive program in experimental philosophy shares the goal of the substantial part of traditional philosophy that is concerned with the analysis of important philosophical concepts. The negative program has implications for philosophical projects whose goal is conceptual analysis. There have been a number of responses to the challenge posed by experimental philosophy's negative program. The chapter also focuses on the expertise defense. (shrink)

Scientific inquiry has revealed that pain is a complex and heterogonous phenomenon that is neither localized to a circumscribed region in the brain nor realized by a unique neurological mechanism. This discovery has inspired the application of a new version of eliminativism–scientific eliminativism–to pain. Based on this view, pain is not a natural kind and should be eliminated from scientific theorizing. Scientific eliminativism applied to pain is purportedly distinct from eliminative materialism because the former does not require elimination (...) of the term ‘pain’ from its quotidian uses in folk psychology. In this paper, I challenge the distinction between scientific eliminativism and eliminative materialism and argue that the two versions of eliminativism make the same claims. I argue further that endorsement of scientific eliminativism for pain leads to elimination of the category of pain from folk psychology. To avoid this outcome, I formulate a proposal that obviates the need for eliminativism in any domain. (shrink)

For a decade or so there has been a new ‘hype’ in educational research: it is called educational neuroscience or even neuroeducation —there are numerous publications, special journals, and an abundance of research projects together with the advertisement of many positions at renowned research centres worldwide. After a brief introduction of what is going on in the ‘emerging sub-discipline’, a number of characterisations are offered of what is envisaged by authors working in this field. In the discussion that follows various (...) problems are listed: the assumption that ‘visual proof’ of brain activity is supposedly given; the correlational nature of this kind of research; the nature of the concepts that are used; the lack of addressing and possibly influencing the neurological mechanism; and finally the need for other insights in educational contexts. Following Bakhurst and others, a number of crucially relevant philosophical issues are highlighted. It is argued that though there are cases where neuroscience insights may be helpful, these are scarce. In general, it is concluded, not a lot may be expected from this discipline for education and educational research. A reminder is offered that the promise of neurophilia may be just another neuromyth, which needs to be addressed by philosophy and education. (shrink)

For a quantum mechanical measurement to be complete, John von Neumann and others assumed that a conscious observer must be present to affect a reduction or collapse of the state function. Also, William James believed that the influence of consciousness on physical bodies is required by the demands of biological evolution. The author shows how both of these ideas might be correct if there exists a neurological mechanism that responds to the presence of an “inside observer” of a (...) kind defined in a previous paper. An experiment is proposed to test the hypothetical mechanism. (shrink)

BackgroundFunctional neurodiagnostics could allow researchers and clinicians to distinguish more accurately between the unresponsive wakefulness syndrome and the minimally conscious state. It remains unclear how it informs surrogate decision-making.ObjectiveTo explore how the next of kin of patients with disorders of consciousness interpret the results of a functional neurodiagnostics measure and how/why their interpretations influence their attitudes towards medical decisions.Methods and SampleWe conducted problem-centered interviews with seven next of kin of patients with DOC who had undergone a functional HD-EEG examination at (...) a neurological rehabilitation center in Germany. The examination included an auditory oddball paradigm and a motor imagery task to detect hidden awareness. We analyzed the interview transcripts using structuring qualitative content analysis.ResultsRegardless of the diagnostic results, all participants were optimistic of the patients’ meaningful recovery. We hypothesize, that participants deal with the results of examinations according to their belief system. Thus, an unfavorable evaluation of the patient’s state had the potential to destabilize the participant’s belief system. To re-stabilize or to prevent the destabilization of their belief system, participants used different strategies. Participants accepted a “positive” HD-EEG result since it stabilized their belief system.ConclusionWe hypothesize, that a group of next of kin of patients with DOC deals with functional neurodiagnostics results on the basis of the result’s value and their high hope that the patient will recover meaningfully. A psychological mechanism seems to moderate the impact of functional neurodiagnostics on surrogate treatment decisions. (shrink)

One gains the impression from occasional remarks in the psychiatric literature that there is a feeling of dissatisfaction with the state of flux of the various concepts, serving as tools to help us understand our patients. This paper is submitted as an attempt to point out some of the reasons why psychiatric notions suffer from certain deficiencies. If, for the time being, we set aside the specific psychiatric problems confronting us in our daily work and muse over the structure of (...) our psychological and psychiatric methods of explanation, we might come to the startling conclusion that these methods are quite inadequate. We medical people think in terms of the mechanistic natural sciences, particularly in terms of physics, chemistry and biochemistry. The importance of these auxiliary sciences to our art of healing the sick increases year after year and the outstanding results of chemotherapy, for instance, show how heavily our profession leans on chemistry. Beyond a doubt, the natural sciences are essential to the pursuit and the development of the practice of medicine, nevertheless, the question arises whether psychiatry should be based upon mechanistic methods in approaching our specific material, the human mind. Posed in this fashion, the question implies that psychiatric thinking is basically mechanistic in its general characteristics. I believe that one can prove this thesis on the premise that descriptions and explanations of human behavior are based upon neurological facts and theories. Since the purpose of neurology lies in a different direction than the goal of psychiatry, it was necessary to alter neurological concepts so that they would be more appropriate and fitting to psychic material, and this elaboration upon neurological principles when applied to mental phenomena leads to psychiatric conceptions with inherent deficiencies. (shrink)

One of the goals of physiologists who study the detailed physical, chemical,and neurological mechanisms operating within the human body is to understand the intricate causal processes which underlie human abilities and activities. It is doubtless premature to predict that they will eventually be able to explain the behaviour of a particular human being as we might now explain the behaviour of a pendulum clock or even the invisible changes occurring within the hardware of a modern electronic computer. Nonetheless, it (...) seems fair to say that hovering in the background of investigations into human physiology is the promise or threat, depending upon how one looks at the matter that human beings are complete physical-chemical systems and that all events taking place within their bodies and all movements of their bodies could be accounted for by physical causes if we but knew enough. I am not concerned at the moment with whether or not this ’mechanistic’ hypothesis is true, assuming that it is clear enough to be intelligible, nor with whether or not we could ever know that it is true. I wish to consider the somewhat more accessible yet equally important question whether our coming to believe that the hypothesis is true would warrant our relinquishing our conception of ourselves as beings who are capable of acting for reasons to achieve ends of our own choosing. I use the word ’warrant’ to indicate that I will not be discussing the possibility that believing the mechanistic hypothesis might lead us, as a matter of psychological fact, to think of human beings as mere automata, as objects whose movements are to be explained only by causes rather than by reasons, as are the actions of a personal subject. I intend to consider only whether the acceptance of mechanism would in fact justify such a change in conception. (shrink)

During the influx of neurological research into France from across Europe that took place rapidly in the late 19th century, the philosophy course in lycées (the French equivalent of high schools) was mobilized by education reformers as a means of promulgating the emergent brain sciences and simultaneously steering their cultural resonance. I contend that these linked prongs of philosophy’s public mission under the Third Republic reconciled contradictory pressures to advance the nation’s scientific prowess following its defeat in the Franco-Prussian (...) war of 1870 without dropping France’s distinct tradition of 19th-century spiritualism, which extended from Maine de Biran’s philosophical psychology to Victor Cousin’s official eclectic spiritualism. Between 1874 and 1902, the French Ministry of Public Instruction transformed philosophy into a national project designed to guide the reception of experimental psychology generally and neurology in particular. This article features original archival research on philosophy textbooks and students’ course notes that illuminate the cultural and intellectual impact of these sciences in the fin de siècle from inside the classroom. I argue that the scientific turn in the psychology section of the lycée philosophy course reflected and brought about a distinct philosophical movement that I call ‘scientific spiritualism’. While historians have analysed philosophy instruction as a mechanism used by the Third Republic to secularize students, this article sheds new light on lycée philosophy professors’ campaign to promote scientific spiritualism as a means to advance incipient brain research and pare its reductionist implications. (shrink)

This study evaluates the ontological and ethical premises and presuppositions of three abortion theorists: Germain Grisez, Eike-Henner W. Kluge, and Michael Tooley. ;Grisez's argument that human embryos and fetuses are moral persons because moral rights are derived from moral value, and the full moral value of human adults who are moral persons is implicit in the living genetic mechanism of all human beings, is criticized on the basis of the tension in Aristotle's doctrine between the notion of essence as (...) an internal causitive principle, and as a set of observable qualities considered to be definitive of the nature of a living thing. However, David Wiggins' use of the semantical theory of natural kind terms of Hilary Putnam is suggested as a possible resolution. ;Kluge's argument that rational beings are moral persons because rational awareness has an absolute and intrinsic value, and that mature fetuses are moral persons because their neurological systems have become sufficiently complex to provide the present capability for rational awareness is criticized because he fails to show that mature fetuses do have such a present capability, and because his discussion of the relationship of potential being to actual being of living things wrongly presupposes that human gestation is analogous to the making of an artifact. ;Tooley's contrary argument that the right to life is not derivable from moral value but must, itself, be something violable, and that there is a conceptual connection between its violation and one's desire to continue to live, excludes fetuses and neonates because they lack the mental capability to desire to continue to live. Tooley's analysis is criticized as incomplete, and his argument as presupposing the existence of an essentially mentalistic self. ;The final chapter is a synthesis which considers the ontology of the development of personality or self, including the theories of Descartes, Locke and Wiggins. The conclusion is reached that theories which claim that a moral person "comes to be" as a fundamentally different kind of being at some point after conception, due to either morphological changes or the development of personality or self, entail dual principles of identity and, hence, are in danger of unintelligibility. (shrink)

Within a physicalist-mechanistic worldview, in which we cannot be more than intelligent, self-reproducing biomachines or biobots, fundamentals of a new approach to the science of human self-explanation are outlined. Some a priori logical necessities, or determinants, of any biobot’s control system design are recognized. Evolution had to satisfy them, but neuroscience and cognitive science so far do not clearly see these basics. It is concluded that the old part of the brain still contains the genetically fixed drives, responses, and the (...) physiological control. Here is the seat of an ancient somatic self that is not intelligent but is still the active center of our life. The neocortex has evolved to serve the somatic self with intelligence by individually building a virtual model of the external material and social world. This model is used by the somatic self to “pre-play” intended actions and responses to see whether they would satisfy its needs. This schema of global brain function provides the neurological foundation for the ego-id dichotomy in analytic psychology, as well as some critique of it. Following the groundbreaking experiments by Benjamin Libet and John-Dylan Haynes et al. , consciousness is taken as a “theater” that presents what the neural networks already have worked out, and freedom of the will is limited. The explosive growth of culture and civilization began when neocortical power exceeded a certain threshold. This can be taken as a quasi-mutation that projected us into a supra-biological space of existence that is new to natural history. It is not clear whether this event will lead to a positive future for humanity or to doom. Functional religion is seen as a neurosystemic attempt to bring back the earlier natural state. Thus, it can be valuable when cleared of mythological ballast. (shrink)

Conventional wisdom suggests mid-task rest as a potential approach to relieve the time-on-task (TOT) effect while accumulating evidence indicated that acute exercise might also effectively restore mental fatigue. However, few studies have explored the neural mechanism underlying these different break types, and the results were scattered. This study provided one of the first looks at how different types of fatigue-recovery break exerted influence on the cognitive processes by evaluating the corresponding behavioral improvement and neural response (EEG power spectral) in (...) a sustained attention task. Specifically, 19 participants performed three sessions of psychomotor vigilance tasks (PVT), with one session including a continuous 30-min PVT while the other two sessions additionally inserted a 15-min mid-task cycling and rest break, respectively. For behavioral performance, both types of break could restore objective vigilance transiently, while subjective feeling was only maintained after mid-task rest. Moreover, divergent patterns of EEG change were observed during post-break improvement. In detail, relative theta decreased and delta increased immediately after mid-task exercise, while decreased delta was found near the end of the rest-inserted task. Meanwhile, theta and delta could serve as neurological indicators to predict the reaction time change for exercise and rest intervention, respectively. In sum, our findings provided novel evidence to demonstrate divergent neural patterns following the mid-task exercise and rest intervention to counter TOT effects, which might lead to new insights into the nascent field of neuroergonomics for mental fatigue restoration. (shrink)

The prominence of Bayesian modeling of cognition has increased recently largely because of mathematical advances in specifying and deriving predictions from complex probabilistic models. Much of this research aims to demonstrate that cognitive behavior can be explained from rational principles alone, without recourse to psychological or neurological processes and representations. We note commonalities between this rational approach and other movements in psychology – namely, Behaviorism and evolutionary psychology – that set aside mechanistic explanations or make use of optimality assumptions. (...) Through these comparisons, we identify a number of challenges that limit the rational program's potential contribution to psychological theory. Specifically, rational Bayesian models are significantly unconstrained, both because they are uninformed by a wide range of process-level data and because their assumptions about the environment are generally not grounded in empirical measurement. The psychological implications of most Bayesian models are also unclear. Bayesian inference itself is conceptually trivial, but strong assumptions are often embedded in the hypothesis sets and the approximation algorithms used to derive model predictions, without a clear delineation between psychological commitments and implementational details. Comparing multiple Bayesian models of the same task is rare, as is the realization that many Bayesian models recapitulate existing (mechanistic level) theories. Despite the expressive power of current Bayesian models, we argue they must be developed in conjunction with mechanistic considerations to offer substantive explanations of cognition. We lay out several means for such an integration, which take into account the representations on which Bayesian inference operates, as well as the algorithms and heuristics that carry it out. We argue this unification will better facilitate lasting contributions to psychological theory, avoiding the pitfalls that have plagued previous theoretical movements. (shrink)

Weaknesses in Roger Sperry's "Defense of Mentalism" that appeared in the Spring issue of JMB are described. Sperry's clarification of his mentalist position still appears to lack a plausible mechanism of interaction. The wheel rolling down hill analogy is described as "a ghost in the subcircuitry." Neurological Positivism's energetic mechanism of brain-mind interaction is summarized. The relatioship of systems theory to reductionism is described briefly in terms of NP.

The adaptive BCI known as ‘closed-loop deep brain stimulation’ (clDBS) is a device that stimulates the brain in order to prevent pathological neural activity and automatically adjusts stimulation levels based on computational algorithms that detect or predict those pathological processes. One of the prominent ethical concerns raised by clDBS is that, by inhibiting or modulating the undesirable neural states of a cognitive agent automatically, the device potentially undermines her autonomy. It has been argued that clDBS is not a threat because (...) autonomy is fundamentally relational, i.e., it essentially depends on external (e.g., social or cultural) factors. If the relational approach to autonomy includes human-computer interaction, then the mechanisms of clDBS, even if external to the brain and exerting some degree of control over the individual, may support her autonomy. However, DBS applications are substantially different from one another, each involving a specific neurological or psychiatric condition, neural target, mechanism and symptom(s), and therefore at least some of them may not fit into the relational analysis. I examine different clDBS applications for treatment resistant depression and claim that while internal capsule/ventral striatum (VC/VS) clDBS is a case of relational autonomy, subgenual cingulate gyrus (Cg25) clDBS is not. Autonomy (relational or otherwise) requires some degree of self-regulation of our motivational states, which is supported by VC/VS DBS but is absent in Cg25 DBS. In Cg25 DBS the device itself directly influences motivational states, thus substituting or overriding (instead of supporting) the auto-regulatory cognitive processes required for autonomous action. (shrink)

Deep Brain Stimulation (DBS) represents a key area of neuromodulation that has gained wide adoption for the treatment of neurological and experimental testing for psychiatric disorders. It is associated with specific therapeutic effects based on the precision of an evolving mechanistic neuroscientific understanding. At the same time, there are obstacles to achieving symptom relief because of the incompleteness of such an understanding. These obstacles are at least in part based on the complexity of neuropsychiatric disorders and the incompleteness of (...) DBS devices to represent prosthetics that modulate the breadth of pathological processes implicated in these disorders. Neuroprostheses, such as an implanted DBS system, can have vast effects on subjects in addition to the specific neuropsychiatric changes they are intended to produce. These effects largely represent blind spots in the current debate on neuromodulation. Anthropological accounts can illustrate the broad existential dimensions of patients’ illness and responses to neural implants. In combination with current neuroscientific understanding, neuropsychiatric anthropology may illuminate the possibilities and limits of neurodevices as technical “world enablers”. (shrink)

Some 20 years ago Todd and colleagues proposed that rhythm perception is mediated by the conjunction of a sensory representation of the auditory input and a motor representation of the body (Todd, 1994a, 1995 ), and that a sense of motion from sound is mediated by the vestibular system (Todd, 1992a, 1993b ). These ideas were developed into a sensory-motor theory of rhythm and beat induction (Todd et al., 1999 ). A neurological substrate was proposed which might form the (...) biological basis of the theory (Todd et al., 2002 ). The theory was implemented as a computational model and a number of experiments conducted to test it. In the following time there have been several key developments. One is the demonstration that the vestibular system is primal to rhythm perception, and in related work several experiments have provided further evidence that rhythm perception is body dependent. Another is independent advances in imaging, which have revealed the brain areas associated with both vestibular processing and rhythm perception. A third is the finding that vestibular receptors contribute to auditory evoked potentials (Todd et al., 2014a, b ). These behavioral and neurobiological developments demand a theoretical overview which could provide a new synthesis over the domain of rhythm perception. In this paper we suggest four propositions as the basis for such a synthesis. (1) Rhythm perception is a form of vestibular perception; (2) Rhythm perception evokes both external and internal guidance of somatotopic representations; (3) A link from the limbic system to the internal guidance pathway mediates the “dance habit”; (4) The vestibular reward mechanism is innate. The new synthesis provides an explanation for a number of phenomena not often considered by rhythm researchers. We discuss these along with possible computational implementations and alternative models and propose a number of new directions for future research. (shrink)

Diversity is an undeniable fact of nature, and there is now evidence that nature did not stop generating diversity just before “designing” the human brain :15,468–15,473. https://doi.org/10.1073/pnas.1509654112, 2015). If neurodiversity is a fact of nature, what about neurodivergence? Although the terms “neurodiversity” and “neurodivergence” are sometimes used interchangeably, this is, we believe, a mistake: “neurodiversity” is a term of inclusion whereas “neurodivergence” is a term of exclusion. To make the difference clear, note that everyone can be said to be neurodiverse, (...) but that it is almost impossible for everyone to be neurodivergent. Neurodivergence is, we claim here, a fact of society. Neurodivergent individuals are those whose cognitive profile diverges from an established cognitive norm, a norm that is not an objective statistical fact of human neurological functioning but a standard established and maintained by socio-political processes. In this paper, we describe the socio-political mechanisms that build neurodivergence out of neurodiversity which, inspired by Mihai :395–416. https://doi.org/10.1057/s41296-017-0186-z, 2018), we call “epistemic and cognitive marginalization”. First, we extend the traditional concept of neurodiversity, which we believe too closely tied to a neuroreductionist conception of cognition, to that of “extended neurodiversity,” thereby viewing neurodiversity through the lens of 4E cognition. Considering that human cognition depends on epistemic resources, both for their construction and their online dynamic expression, we hypothesize that the differential access to epistemic resources in society, a form of epistemic injustice, is an overlooked mechanism that turns neurodiversity into neurodivergence. In doing so, we shed light on a type of epistemic injustice that might be missing from the epistemic injustice literature: cognitive injustices. (shrink)

This paper selectively reviews the neurophysiological evidence for shared neural circuits (supposedly implemented by mirror neurons) as the mechanism underlying empathy. I will argue that while the mirror neuron system plays a role in motor resonance, it is not possible to conclude that this system is critically involved in emotion recognition, and there is little evidence for its role in empathy and sympathy. In addition, there is modest support from neurological observations that lesion of the regions involved in (...) the mirror neuron system leads to dysfunction in empathy, whereas damage of the ventromedial prefrontal cortex is associated with such impairment. To significantly advance our understanding of the mechanisms underlying empathy, research needs finer conceptualization, better designed paradigms, and integration with knowledge from lesion studies. (shrink)

The NIH-funded Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative has led to significant advances in what we know about the functions and capacities of the brain. This multifaceted and expansive effort supports a range of experimentation from cells to circuits, and its outputs promise to ease suffering from various neurological injuries, diseases, and neuropsychiatric conditions. At the midway point of the 10-year BRAIN Initiative, we pause to consider how these studies, and neuroscience research more broadly, may bear on (...) human characteristics and moral concepts such as identity, agency, and others. This midway point also offers us an opportunity to evaluate the sociology and impacts of BRAIN Initiative-funded investigations to ensure that ethical standards of fairness and justice pervade the scientific process itself. Neuroethics inquiry provides a mechanism to invite relevant, novel expertise from the wide array of disciplines that intersect with biomedicine in neuroscience research. As the BRAIN Initiative and the broader field of neuroscience proceed, neuroethics serves as a central component of neuroscience inquiry to i) foster necessary and beneficial collaborations for responsible discovery; ii) ensure a rigorous, reproducible, and representative neuroscience research process; and iii) explore the unique nature of study of the human brain through accurate and representative models of its function and dysfunction. (shrink)

Recent work in experimental philosophy shows that folk intuitions about moral responsibility are sensitive to a surprising variety of factors. Whether people take agents to be responsible for their actions in deterministic scenarios depends on whether the deterministic laws are couched in neurological or psychological terms (Nahmias et. al. 2007), on whether actions are described abstractly or concretely, and on how serious moral transgression they seem to represent (Nichols & Knobe 2007). Finally, people are more inclined to hold an (...) agent responsible for bringing about bad than for bringing about good side effects that the agent is indifferent about (Knobe 2003). Elsewhere, we have presented an analysis of the everyday concept of moral responsibility that provides a unified explanation of paradigmatic cases of moral responsibility, and accounts for the force of both typical excuses and the most influential skeptical arguments against moral responsibility or for incompatibilism. In this article, we suggest that it also explains the divergent and apparently incoherent set of intuitions revealed by these new studies. If our hypothesis is correct, the surprising variety of judgments stems from a unified concept of moral responsibility. -Knobe, J. (2003) Intentional Action and Side Effects in Ordinary Language. Analysis 63, pp.190–93. -Nahmias, E.; Coates, J.; Kvaran. T. (2007) Free will, moral responsibility, and mechanism: experiments on folk intuitions. Midwest studies in Philosophy XXXI -Nichols, S.; Knobe, J. (2007) Moral responsibility and determinism: the cognitive science of folk intuitions, Noûs 41:4, 663-685. (shrink)

Loïc Wacquant argues for a radicalization of the habitus concept provided by Pierre Bourdieu, suggesting that habitus is a site and mode for conducting research, not simply an explanatory or theoretical mechanism. Taking seriously this call to examine skills and communities of practice through apprenticeship, however, requires that the theoretical account of habitus be subject to empirical testing. Moreover, enquiry into communities of practice, especially the subtle psychological, behavioural and even neurological consequences of skill acquisition, means that claims (...) about the habitus can be scrutinized by fields such as psychology, neurology and even human biology. Habitus as a truly open path of inquiry will demand, not wholly novel concepts, but a recognition of when claims about practice are simultaneously testable, and falsifiable, by other forms of empirical enquiry, including the human sciences. (shrink)

Where does consciousness come from? For most scientists and laypeople, it is axiomatic that something in the substance of the brain - neurons, synapses and grey matter in just the right combination - create perception, self-awareness, and intentionality. Yet despite decades of neurological research, that ""something"" - the mechanism by which this process is said to occur - has remained frustratingly elusive. This is no accident, as the authors of this book argue, given that the evidence increasingly points (...) to a startling fact: consciousness may not, in fact, reside in the brain at all. In this wide-ranging and deeply scientific book, Imants Baruss and Julia Mossbridge utilise findings from special relativity and quantum mechanics, modern and ancient philosophers, and paranormal psychology to build a rigorous, detailed investigation into the origins and nature of human consciousness. Along the way, they examine the scientific literature on concepts including mediumship, out-of-body and near-death experiences, telekinesis, ""apparent"" versus ""deep time,"" and mind-to-mind communication, and introduce eye-opening ideas about our shared reality. The result is a revelatory tour of the ""post-materialist"" world, and a roadmap for consciousness research in the twenty-first century. (shrink)

Over the last decade, Deep Brain Stimulation (DBS) has garnered significant attention as a potential treatment for psychiatric and neurological conditions (Alho et al. 2022). As our mechanistic und...

To ascribe a telos is to ascribe a norm or standard of performance. That fact underwrites the plausibility of, say, teleological theories of mind. Teleosemantics, for example, relies on the normative character of teleology to solve the problem of “intentional inexistence”: a misrepresentation is just a malfunction. If the teleological ascriptions of such theories to natural systems, e.g., the neurological structures of the brain, are to be literally true, then it must be literally true that norms can exist independent (...) of intentional and psychological agency. Davies, for one, has argued that such norms are impossible within a naturalistic worldview. Consequently, teleological theories of mind, for example, cannot be literally true. I will show, however, that the truth conditions on normative statements do not presuppose intentional and psychological agency and, further, that a selectional regime is one naturalistic mechanism that satisfies those truth conditions. Norms, then, exist in the world independent of intentional and psychological agency. (shrink)

While research has consistently found that general distress and psychopathology are not predictive of sexual recidivism, examination of specific syndromes and their relationship to offending has revealed a potentially more complicated relationship. One proposed mechanism for the mixed findings with respect to major mental illness and sexual offending may be the confound of neurological injury. As identified in Mann et al. work on psychologically meaningful risk factors, mental illness represents an area in need of more study given the (...) indirect influence it may exert on risk. To this end, the current paper summarizes the study of the relationship between neurological injury, psychosis and problematic sexual behavior among two Canadian samples of forensic and civil psychiatric patients. In the first study we observed higher than expected rates of sexually-themed psychotic symptoms and problematic sexual behavior among a combined group of forensic and civil psychiatric patients. Indeed 70 percent of those individuals who engaged in PSB endorsed sexually-themed psychotic symptoms. While comorbidity is common amongst this group, brain injury appeared to represent a specific liability. Compared to those who did not engage in PSB, those who did were almost 4x more likely to have a documented history of brain injury. In the second study we sought to replicate this finding in a larger forensic sample of 1,240. However, the recorded rates of brain injury were significantly less, such that no relationship to PSB was observed. Based on the mixed findings to date, including our own data, questions remain about the nature of a potential shared vulnerability for psychosis and PSB previously postulated. Among psychiatrically complex individuals who engage in PSB, understanding etiology and links to risk are helpful, but perhaps more importantly is attention to the mechanisms through which symptoms confer risk and how best to treat and manage them. (shrink)

In the introduction to the Phenomenology of Perception, Merleau-Ponty states that ‘Attention, [...] as a general and formal activity, does not exist’. This paper examines the meaning and truth of this difficult and surprising statement, along with its implications for the account of perception given by theorists such as Dretske and Peacocke. In order to elucidate Merleau-Ponty’s phenomenological account of human perception, I will present two alternative models1 of how attention might be thought to operate. The first is derived from (...) the works of the aforementioned theorists and is, I argue, based upon a largely inaccurate computational or mechanistic understanding of the mind. The second is drawn from the works of Merleau-Ponty and cognitive scientist and philosopher, Alva Noë, and takes into account recent neurological theories concerning the role of attention in human consciousness. On the basis of these models I will argue that attention is an essential, rather than incidental, characteristic of consciousness that is constitutive of both thought and perception, and which cannot be understood in terms of the independent faculty or ‘general and unconditioned power’ that Dretske et al’s account requires. I will conclude by considering two potential counterexamples to my argument, and evaluating the threat that these pose to the phenomenological model. (shrink)

In the past, researchers have focused mainly on the effects and consequences of self-awareness; however, they have neglected a more basic issue pertaining to the specific mechanisms that initiate and sustain self-perception. The author presents a model of self-awareness that proposes the existence of 3 sources of self-information. First, the social milieu includes early face-to-face interactions, self-relevant feedback, a social comparison mechanism that leads to perspective taking, and audiences. Second, contacts with objects and structures in the physical environment foster (...) self–world differentiation in infants; this environment also contains self-focusing and reflecting stimuli, such as mirrors and video cameras. Third, the self can develop bodily awareness through proprioception and can reflect on itself using imagery and inner speech. Furthermore, self-awareness is mainly mediated by the prefrontal lobes. The author establishes various links among these different neurological, social, ecological, and cognitive elements of the model. (shrink)

We usually withhold attributions of moral responsibility when a person acts on preferences that are induced without her consent by other people by means of conditioning, post-hypnotic suggestion, neurological fiddling and similar techniques. However, this is not generally the case when a person induces preferences in herself by the process of character building. However, the distinction between non-responsibility and responsibility for preferences does not map neatly onto the distinction between psychological induction by other and by self. Sometimes responsibility-grounding freedom (...) of action and autonomy of will re compromised when a person induces preferences in herself by adaptive preference-formation, the mechanism that sets up the cry of “sour grapes.” They can also be compromised when a person intentionally undertakes a strategy of self-abnegating resignation to oppressive necessity. It remains unclear, nonetheless, how the unfreedom and heteronomy of preferences calibrated to the merely feasible contrasts with the freedom and autonomy of planned preferences-changes guided by the person’s own values in projects of character building. (shrink)

This essay provides an analysis of the clinical problems that arise at the borderline between neurology and psychiatry. We postulate that psychopathological and neuropathological constructs have distinct referents and conceptual fields, but they are not mutually exclusive categories. After establishing criteria for defining neuropsychiatric constructs, we outline rules for identifying cases where a significant relationship exists between neuropathological and psychopathological patterns. We propose three approaches to establishing this relationship: a clinical epidemiology approach, a clinical neuroscience approach offering a mechanistic model, (...) and a longitudinal study of individual cases incorporating idiographic perspectives. We discuss the logic of brain-behavior relationships and emphasize the need for closer academic feedback between neuroscientific research and clinical practice to better understand the causality of psychopathological phenomena in the context of neuropsychiatry. While precise demarcation may be challenging in some cases, we provide two types of examples: first, straightforward cases where neuropathology explains psychopathological patterns; second, complex cases that require studying the causal interactions between neuropathological factors, psychological factors, and sociocultural contexts, leading to intricate clinical patterns that demand cognitive neuropsychiatry resources, and a multidisciplinary approach to clinical care. (shrink)

Traditionally, identity and supervenience have been proposed in philosophy of mind as metaphysical accounts of how mental activities (fully understood, as they might be at the end of science) relate to brain processes. Kievet et al. suggest that to be relevant to cognitive neuroscience, these philosophical positions must make empirically testable claims and be evaluated accordingly – they cannot sit on the sidelines, awaiting the hypothetical completion of cognitive neuroscience. We agree with the authors on the importance of rendering these (...) positions relevant to ongoing science. We disagree, however, with their proposal that a metaphysical relationship (identity or supervenience) should “serve as a means to conceptually organize and guide the analysis of neurological and behavioral data” (p. 7). Instead, we advance a different view of the goals of cognitive neuroscience and of the proper means of relating metaphysics and explanation. Our central objection to the psychometric approach deployed by Kievet et al. is that the formal models only account for correlations between variables (measurements) and do not aid in explaining phenomena. Cognitive neuroscience is concerned with the latter. We develop this point in section 2 in which we present what we find to be problematic in their proposed models. In section 3 we advance an account of what is required to explain phenomena: (a) providing an adequate description of a phenomenon; and (b) characterizing the mechanism responsible for it. In doing so we will characterize a version of the identity theory, heuristic identity theory (HIT) which figures centrally in developing such explanations and illustrate its role in what we take to.. (shrink)

. Ably marshalling ideas from theology, philosophy, and neurology, personality theorist Joseph F. Rychlak criticizes mechanistic psychologists' neglect of will and responsibility; these human qualities involve dialectically considering alternatives. I disagree with Rychlaks suggestion of fundamental mystery in the minds transcendence of the body and believe transcendent mind is intimately related to biological evolution and the brain. For example, dialectics, seen in simpler forms in lower animals, may require neural inhibition, feedback circuits, and topographic mappings. However, epistemologically speaking, neuroscientists strongly (...) need the human insights of work such as Rychlak's to understand the alternatives, in planning investigation at more microscopic levels. (shrink)

For the last thirty years, cognitive scientists have attempted to describe the cognitive architecture of typically developing human beings, using, among other sources of evidence, the dissociations that result from developmental psychopathologies such as autism spectrum disorders, Williams syndrome, and Down syndrome. Thus, in his recent defense of the massive modularity hypothesis, Steven Pinker insists on the importance of such dissociations to identify the components of the typical cognitive architecture (2005, 4; my emphasis): This kind of faculty psychology has numerous (...) advantages (...). It is supported by the existence of neurological and genetic disorders that target these faculties unevenly, such as a difficulty in recognizing faces (and facelike shapes) but not other objects, or a difficulty in reasoning about minds but not about objects or pictures. Similarly, Simon Baron-Cohen writes (1998, 335; my emphasis; see also Temple, 1997): I suggest that the study of mental retardation would profit from the application of the framework of cognitive neuropsychology (…). In cognitive neuropsychology, one key question running through the investigator’s mind is “Is this process or mechanism intact or impaired in this person?” When cognitive neuropsychology is done well, a patient’s cognitive system is examined with specific reference to a model of the normal cognitive system. And, not infrequently, evidence from the patient’s cognitive deficits leads to a revision of the model of the normal system. However, in recent years, the use of developmental psychopathologies to identify the components of the typical cognitive architecture has come under heavy fire. In a series of influential articles, neuropsychologist Annette Karmiloff-Smith has argued that findings about the pattern of impairments and preserved capacities in people with developmental psychopathologies say nothing about the cognitive architecture of.. (shrink)

Online medical reference websites are utilized by health care providers to enhance their education and decision making. However, these resources may not adequately reveal pharmaceutical-author interactions and their potential conflicts of interest. This investigation: evaluates the correspondence of two well-utilized CoI databases: the Centers for Medicare and Medicaid Services Open Payments and ProPublica’s Dollars for Docs and quantifies CoIs among authors of a publicly available point of care clinical support website which is used to inform evidence-based medicine decisions. Two data (...) sources were used: the hundred most common drugs and the top fifty causes of death. These topics were entered into a freely available database. The authors were then input into CMSOP and PDD and compensation and number of payments were determined for 2013–2015. The subset of highly compensated authors that also reported “Nothing to disclose” were further examined. There was a high degree of similarity between CMSOP and PDD for compensation and payment number. The amount received was 1.4% higher in CMSOP than in PDD. The articles where the authors had received the greatest compensation were in neurology, oncology, and endocrinology. Two authors reporting “Nothing to disclose” received appreciable and potentially relevant compensation. CMSOP and PDD produced almost identical results. CoIs were common among authors but self-reporting may be an inadequate reporting mechanism. Recommendations are offered for improving the CoI transparency of pharmaceutical-author interactions in point-of-care electronic resources. (shrink)

Stuttering is one of the most well-known speech disorders, but the underlying neurological mechanisms are debated. In addition to genetic factors there are also major non-genetic contributions. It is here proposed that infection with group A beta-hemolytic streptococcus (GAS) was a major underlying cause of stuttering until the mid 1900s, when penicillin was introduced for the treatment of streptococcal infections about 1946. The main mechanism proposed is an autoimmune reaction from tonsillitis, targeting specific molecules, for example within the (...) basal ganglia. It is here also proposed that GAS infections may have continued to cause stuttering to some extent, to the present date, though more rarely. If so, early diagnosis of such cases would be of importance. Childhood cases with sudden onset of stuttering after throat infection may be particularly important to assess for possible GAS infection. The support for this hypothesis primarily comes from three lines of argument. First, medical record data from the 1930s strongly indicates that there was one type of medical event in particular that preceded the onset of childhood stuttering with unexpected frequency: diseases related to GAS throat infections. In particular, this included tonsillitis and scarlet fever, but also rheumatic fever. Rheumatic fever is a childhood autoimmune sequela of GAS infection, which was a relatively widespread medical problem until the early 1960s. Secondly, available reports of changes of the childhood prevalence of stuttering indicates striking parallels between stuttering and the incidence of rheumatic fever, with (1) decline from the early 1900s, (2) marked decline from the introduction of penicillin about 1946, and (3) reaching a more stable level in the 1960s. The correlations between the data for stuttering and for rheumatic fever after introduction of penicillin are very high, at about 0.95. Thirdly, there are established biological mechanisms linking GAS tonsillitis to immunological effects on the brain. In addition, a small number of more recent case reports have provided further support for the hypothesis linking stuttering to GAS infection. Overall, it is proposed that the available data provides strong evidence for the hypothesis that GAS infection was a major cause of stuttering until the mid 1900s. (shrink)

The aetio-pathogenetic sequences and the physio-pathological patterns of diabetes, emphysema, cholera, circulatory shock and thrombosis have been analysed with respect to an evolutionary interpretation. The diseases, although reflecting alterations of processes that can always be described in physico-chemical language, occur only at the level of biological systems which reflects the decodification of genomic project: the teleonomic projects that have been developed during evolution. The concepts of evolutionary emergence and of downward causation have been used to discuss the relationship between the (...) molecular events responsible for the initiation of the disease, and the subsequent events responsible for the aetio-pathogenesis, for the systemic disarrangement and for the additional alterations of tissues and cells independent of the initial molecular events. In diabetes the systemic disarrangement, glycosuria and hyperglycemia, reflect the evolutionary emergence of the processes regulating carbohydrate metabolism, whereas the cardiovascular and neurological alterations are effects of the systemic disarrangement by a mechanism of downward causation. The complexity of the aetio-pathogenesis and of the physio-pathological patterns of diseases is due to the generation of information during the evolution of multi-hierarchical entities. The evolutionary epistemology approach is useful to explain the behaviour of complex systems. (shrink)

This paper proposes to examine the contribution of Goldstein’s biological thinking to French philosophy in the immediate post-war years. We will begin by reiterating the idea of mankind in Goldstein’s contemporary neurology. We will then recount the quarrel which took place between mechanist and vitalist biologists to show that criticism of the reflex concept is the condition to envision biology as a creative act. Finally, we will expose the ways French structuralist criticism of the subject used German structuralism to fuel (...) its contestation of the idea of a human nature based on reason. (shrink)

The Origins of Consciousness challenges the dominant view that consciousness is an emergent property of the complex human brain. Based on his pioneering research on a variety of organisms, Vallortigara argues that the most basic forms of mental life do not require large brains, and that the neurological surplus observed in some animals such as humans is likely at the service of memory storage, not of the processes of thought or, even less, of consciousness. The book argues for a (...) simple neural mechanism that can provide the crucial event that brings into effect the minimum condition for subjective experience. Implications of the hypothesis for the appearance of consciousness in different organisms are discussed, as well as links with a variety of fascinating human phenomena such as disorders of consciousness, tickling, and visual illusions. Challenging widely accepted theories of consciousness, the book is a must-read for students and researchers of human and animal consciousness. (shrink)

For hundreds of years, death had been defined by cardiopulmonary criteria. When heart and respiratory functions were permanently absent, doctors declared their patients dead. Three developments in intensive care medicine called into question these widely-accepted criteria, however: the advent of positive pressure ventilation and the promotion of cardiopulmonary resuscitation, both in the early 1950s, and the first successful heart transplantation in 1967. What had previously been diagnosed as the permanent absence of vital functions, suddenly became reversible. Not only could doctors (...) replace a defective heart with a functioning transplant; patients could also be kept oxygenated in the total absence of spontaneous respiratory function. The traditional boundaries between life and death became blurred. Patients for whom there was not the remotest possibility of regaining consciousness following massive brain damage continued to consume valuable medical resources. Moreover, their organs could not be procured for transplantation. Were those patients still alive or could the ventilators be switched off? A criterion suited to indicate a patient’s death despite the provision of external life support was needed. In 1968 an ad hoc committee of the Harvard Medical School published the first comprehensive definition of what would soon become the new clinical standard: brain death. The brain bears a special relation to other organs; it directs bodily functions without carrying them out. When the brain is destroyed, it was argued, this control mechanism is irreversibly dysfunctional, so that the organism becomes unable to maintain its vital functions, loses its somatic unity and, consequently, ceases to exist. This neurological criterion has been controversial ever since its introduction. Whether brain death is indeed death is what I shall be investigating in this thesis. I will be asking three main questions: What are we? Is brain death the death of an organism? Is brain death the death of a psychological being? The question of personal identity and the question of the appropriate definition of death are intimately related. Only when we have determined what kind of entity we essentially are can we specify what conditions must apply for this entity to persist or to cease to exist. I shall argue that we are essentially psychological beings, which entails that our death is distinct from the death of our organisms. Hence, we need two different criteria – one for the death of each entity. I shall try to establish whether brainstem death and whole-brain death correspond to the irreversible cessation of organismic functioning. I will then determine by which criterion the death of a psychological being can be diagnosed. (shrink)

Despite its importance, abnormal interactions between the proximal and distal upper extremity muscles of stroke survivors and their impact on functional task performance has not been well described, due in part to the complexity of upper extremity tasks. In this pilot study, we elucidated proximal–distal interactions and their functional impact on stroke survivors by quantitatively delineating how hand and arm movements affect each other across different phases of functional task performance, and how these interactions are influenced by stroke. Fourteen subjects, (...) including nine chronic stroke survivors and five neurologically-intact subjects participated in an experiment involving transport and release of cylindrical objects between locations requiring distinct proximal kinematics. Distal kinematics of stroke survivors, particularly hand opening, were significantly affected by the proximal kinematics, as the hand aperture decreased and the duration of hand opening increased at the locations that requires shoulder abduction and elbow extension. Cocontraction of the extrinsic hand muscles of stroke survivors significantly increased at these locations, where an increase in the intermuscular coherence between distal and proximal muscles was observed. Proximal kinematics of stroke survivors was also affected by the finger extension, but the cocontraction of their proximal muscles did not significantly increase, suggesting the changes in the proximal kinematics were made voluntarily. Our results showed significant proximal-to-distal interactions between finger extension and elbow extension/shoulder abduction of stroke survivors exist during their functional movements. Increased cocontraction of the hand muscles due to increased neural couplings between the distal and proximal muscles appears to be the underlying mechanism. (shrink)

here has been a large number of studies in neurological sciences on how human brain works, especially in reading and parallel information processing. So I think this statement is really sweeping. Perhaps it is better to knowledge the abilities of human brains and to comment on the limitations of the human brain. The book “Adapt” by Tim Hartford advocates micro-step changes. An important aspect in this area is to understand the processes involved behind the scenes so that it gives (...) us a better formulation of the creativity algorithms involved. I will try to put in some pointers on the depths to which higher level intelligence has been simulated by AI in the past years. Some of the higher level intelligence mechanisms such as creativity, dreams and logical thinking have been implemented in machines in certain ways. However, they are still not implemented in the way humans do the same. The exact mechanism in which these intelligence mechanisms are used by human brains is still way ahead of that done by computers. However, we now look at other aspects in them as well as other functions which might be explored in the years ahead in AI. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:A Still Life Is Really a Moving LifeThe Role of Mirror Neurons and Empathy in Animating Aesthetic ResponseCarol S. Jeffers (bio)IntroductionIn the Western aesthetic canon, the still life enjoys a certain prestige; its place in the museum and on the pages of the art history text is secure. Art aficionados who appreciate the character of Cezanne's apples help to ensure the lofty standing of the still life, as do (...) students who admire the dewdrops still glistening on flowers picked and painted in the nineteenth century. For some students, however, it is difficult to understand such veneration. Despite the coaxing of dedicated art or museum educators, these students find apples nestled among drapery folds or translucent petals in a spring bouquet to be "boring." No matter how compelling the apples, how exquisitely rendered the blossoms, the still life is much too static, offering little more than the lifelessness of inanimate objects.In my experience, even the most unappreciative of students can be persuaded to take a closer look at the inanimate—not by me or any strategies I may have devised but rather by classmates who have chosen still life paintings to serve as their personal metaphors. When shared during the courses I teach, these still lifes and their depicted objects acquire special meanings that are uniquely associated with the individual students who chose them. Reflecting on these class presentations, converted students offered these thoughts: "I related myself with the metaphors and the way my classmates felt"; and "What really stayed with me were the stories and the way my classmates connected with their paintings—how they connected to the art emotionally." Still another wrote: "I really liked the way their presentations went because I got to know [my classmates] a little bit more." Through these connections to still life and other genres, students explored [End Page 31] their concepts of self within a community of others and began to experience the power of empathy.Empathy, typically defined as "the intellectual or emotional identification with another,"1 is a human capacity that, according to the noted neuroscientist Vittorio Gallese, allows us to understand the world of objects as well as the world of others.2 With the recent discovery of the mirror neuron system in the human brain, Gallese and other investigators around the world have identified the neurological basis of empathy.3 Subsequent studies of the remarkable properties of mirror neurons have yielded potent new understandings of the connections between empathy, objects of art and material culture, and intrapersonal relationships among human beings. Interestingly, these twenty-first-century findings tend to confirm a nineteenth-century connection between aesthetics and empathy, or more precisely, Einfuhlung ("in-feeling," or "feeling into"), a term coined by the philosopher Robert Vischer in 1873 to describe the projection of human feeling onto art objects.4 As Vischer himself described this phenomenon, "I transport myself into the inner being of an object and explore its formal character from within, as it were."5These insights, whether gained through the use of state-of-the-art brain imaging technologies or dusty volumes in a German library, have led Gallese to consider some interesting implications, such as, for example, those involving the still life—its bottles, apples, even its brushstrokes—and to claim that "a still life is really a moving life" when understood from the perspective of neuroscience.6 To explore this claim and its relevance to classroom and museum practices, this article examines the relationship between mirror neurons, empathy, and aesthetic response as it developed among preservice teachers who presented metaphorical works of art in two teacher education courses. A brief synopsis of research results highlighting the workings of the mirroring mechanism is presented and then applied to two student presentations: one given by Molly about Cezanne's Still Life with Apples (1893-94) and the other by Deborah about Fantin-Latour's White and Pink Mallows in a Vase (1895). The stories told by Molly, Deborah, and their classmates allow additional insights with implications for art and museum education.Mirror Neurons: Some Research ResultsSome fifteen years ago, what Gallese characterizes as a "strange class" of neurons was discovered, first... (shrink)