Antimicrobial resistance (AMR) has become one of the defining challenges of the twenty-first century. Food production and farming are a key if troubling component of that challenge. Livestock production accounts for well over half of annual global consumption of antimicrobials, though the contribution of the sector to drug resistance is less clear. As a result, there is an injunction to act in advance of incontrovertible evidence for change. In this paper we engage with the role of market actors in the (...) precautionary regulation of farming practices and AMR threats. The paper takes the UK poultry sector as exemplary of an audit-led process that has, in recent years, achieved impressive reductions in antimicrobial use. Using qualitative interview data with farmers and veterinarians we chart the changing practices that have accompanied this reduction in treatments. We use this analysis to raise some cautions around audit-led systems of regulation. Audits can lock farms and animals into particular versions of farming and animal health; they can elevate harmful compensatory practices (including disinfectant uses); and they can reproduce an actuarial approach to an issue that does not fit the conventions of risk management. The paper presents the considerable successes that have been achieved over a short period of time in a livestock sector, while generating notes of caution concerning the audit-led management of livestock-related AMR threats. (shrink)

Formalised knowledge systems, including universities and research institutes, are important for contemporary societies. They are, however, also arguably failing humanity when their impact is measured against the level of progress being made in stimulating the societal changes needed to address challenges like climate change. In this research we used a novel futures-oriented and participatory approach that asked what future envisioned knowledge systems might need to look like and how we might get there. Findings suggest that envisioned future systems will need (...) to be much more collaborative, open, diverse, egalitarian, and able to work with values and systemic issues. They will also need to go beyond producing knowledge about our world to generating wisdom about how to act within it. To get to envisioned systems we will need to rapidly scale methodological innovations, connect innovators, and creatively accelerate learning about working with intractable challenges. We will also need to create new funding schemes, a global knowledge commons, and challenge deeply held assumptions. To genuinely be a creative force in supporting longevity of human and non-human life on our planet, the shift in knowledge systems will probably need to be at the scale of the enlightenment and speed of the scientific and technological revolution accompanying the second World War. This will require bold and strategic action from governments, scientists, civic society and sustained transformational intent. (shrink)

The scientific, ethical, and policy issues raised by research involving the engraftment of human neural stem cells into the brains of nonhuman primates are explored by an interdisciplinary working group in this Policy Forum. The authors consider the possibility that this research might alter the cognitive capacities of recipient great apes and monkeys, with potential significance for their moral status.

How do educators better reach their students, better capture their attention and imagination without sacrificing scholarship? Teachable Moments: Essays on Experiential Education examines the pedagogy of Prescott College, a school that has embraced experiential education and been finding success with it for over thirty years. These essays—from scholars in fields as wide ranging as religious studies, environmental science, psychology, dance, literature, adventure education, and peace studies—examine the challenges and, ultimately, the rewards of student-centered education.

Since Kathrine Switzer broke into the Boston Marathon in 1967 by registering with the gender neutral initials K. V., women’s participation in racing events has risen decade by decade: Running USA reports that 57 percent of finishes recorded in 2014 were posted by women. Key milestones have been reached, including the inauguration of the women’s marathon at the 1984 Los Angeles Olympics and the passing of Title IX in the United States in 1972, which guarantees support for women’s athletic programs (...) at the college level. But most remarkable has been the increase in women’s activity at the community level, made manifest in the number of organized races, often held to support women’s health initiatives, as well... (shrink)

This essay concerns the theories of the sublime proposed by Alexander Gerard, Henry Home (Lord Kames), Archibald Alison, and Dugald Stewart. All four thinkers, I argue, aim to provide a philosophical account of the unity of the concept of the sublime, i.e., to respond to the question: what might all objects, art works, etc. that have been identified as sublime (or “grand”) in the philosophical, literary, art-theoretical, and rhetorical tradition have in common? Yet because they find the objects (...) called “sublime” to be so disparate, and because – contra Burke and Kant, the classical philosophical theorists of the sublime, they cannot identify one single feeling that could define the experience of the sublime, they ultimately endorse (what we would call) a “family-resemblance” view of the sublime: certain objects cause in us certain feelings (and so are classed together); other objects are then (for other reasons, i.e., not because they give us similar feelings) associated with some of the previous objects – and therefore we take these objects, and the feelings they may arouse, as sublime as well. Some – notably Gerard and Allison – take our act of appreciation of the sublime to be itself an act of free imaginative association, connecting the perceived object to other objects, memories, feelings, etc. The importance of association in aesthetic appreciation itself might also suggest that the category of the sublime must be a pluralistic and open one: because we may always find new objects sublime, via new associations. As a result, I suggest, these thinkers – by contrast to many other writers on the sublime – allow that art can be as sublime, or even more sublime, than natural objects and indeed can render natural objects sublime. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Kant's Transcendental Deduction by Alison LaywineKatherine DunlopAlison Laywine. Kant's Transcendental Deduction. Oxford: Oxford University Press, 2020. Pp. iv + 318. Hardback, $80.00.Alison Laywine's contribution to the rich literature on Kant's "Transcendental Deduction of the Categories" stands out for the novelty of its approach and conclusions. Laywine's declared "strategy" is "to compare and contrast" the Deduction with the Duisburg Nachlaß, an important set of manuscript jottings from (...) the 1770s (10). But her approach is also deeply informed by Kant's writings on metaphysics from the 1750s and 1760s; moreover, she gives attention to ancient Greek geometry and its importance for Kant's thought.I believe Laywine's most important interpretative claim is that the Transcendental Deduction's "final step" addresses "the question of how nature is possible" (210). Here, 'nature' is understood in what Kant calls the "formal sense," as "the totality of rules under which appearances must stand if they are to be thought as joined in one experience" (Prolegomena, §36; cf. B 165). This constitutes a novel answer to the problem posed in Dieter Henrich's landmark 1969 paper "The Proof Structure of the Transcendental Deduction" (Review of Metaphysics 22 [1969]: 640–59): how to understand §§21–26 of the (B-edition) Deduction as proving more than the thesis already stated in §20 (that the manifold in an intuition necessarily stands under the categories).Crucial support for Laywine's interpretation comes from §26 of the Deduction, which claims the possibility of cognizing objects "a priori through categories... as far as the laws of their combination are concerned, thus the possibility of as it were prescribing the law to nature and even making [nature] possible," is now "to be explained" (B 159). Kant does not use the term 'world' in this passage (as he does in Prolegomena §36). But Laywine contends that here the word 'nature' "has unmistakable, deliberate, cosmological connotations," and in fact "means 'world' in the sense of Kant's early cosmology": roughly, a whole unified by means of laws (12–13).The "cosmological" language of §26 does not recur in the following, officially concluding, section of the Deduction. So, we might ask whether Kant's explanation of how the understanding prescribes laws to nature is integral to the Deduction; Henry Allison, for instance, describes this explanation as an "appendix" (Kant's Transcendental Deduction: An Analytical-Historical Commentary [Oxford: Oxford University Press, 2015], 9). The question of whether it belongs integrally has bite because, as Laywine makes clear in her "Conclusion," the universal laws at issue are just the Analogies of Experience. Thus, the passage could be read as the "promissory note with a forward-looking reference to the System of Principles" that she finds missing from the Deduction (289). Laywine meets such worries by arguing that "the reappropriation [from the pre-Critical period] of the general cosmology is actually [End Page 162] doing... a lot of hard work" in the Deduction (13). This sustained argument comes to a head in chapter 4, which contends that each of the two steps into which Laywine divides the first half of the (B-edition) Deduction, treated in chapters 2 and 3 (respectively), relies on cosmological presuppositions.Chapter 2 analyzes the conception of knowledge as relation to an object that is asserted (in §17) to rely on the synthetic unity of apperception. Laywine traces this conception to the Duisburg Nachlaß's account of "exposition," which relates concepts a priori to appearances, in something like the way that geometrical construction relates them to pure intuition. (Laywine further connects the Latin term expositio to the Greek ekthesis, which expositio translates in the context of geometrical proof. She thereby gives the notion of ekthesis broader importance than does Jaakko Hintikka, who noted its relevance to Kant's philosophy of mathematics in "Kant on the Mathematical Method" [Monist 51 (1967): 352–75]. Laywine claims that Borelli's edition of Euclid could have been Kant's source for the term, but I doubt it was known to Kant and his contemporaries, since it is not among the editions cited by Christian Wolff; Commandino seems likelier to me. Chapter 2 is concerned to articulate the notion of... (shrink)

The authors of this volume — all of them recognized representatives of a wide range of academic disciplines — agree that Locke’s work must have had a considerable influence both on English and German literature and the visual arts of Great Britain, especially in the eighteenth and nineteenth centuries. From the perspective of interdisciplinarity and intertextuality, the essays presented here deal with Locke as a source of ideas for Archibald Alison, John Constable, Daniel Defoe, Henry Fielding, Oliver Goldsmith, (...) Johann Timotheus Hermes, William Hogarth, Immanuel Kant, Martin Knutzen, Gottfried Wilhelm von Leibniz, Gotthold Ephraim Lessing, George Lillo, Edward Moore, Johann Gottwerth Müller, Joshua Reynolds, Samuel Richardson, John Ruskin, Joseph Spence, Laurence Sterne, J. M. W. Turner and Thomas Whately, among others. (shrink)

Part I: The Life of Cognitive Science:. William Bechtel, Adele Abrahamsen, and George Graham. Part II: Areas of Study in Cognitive Science:. 1. Analogy: Dedre Gentner. 2. Animal Cognition: Herbert L. Roitblat. 3. Attention: A.H.C. Van Der Heijden. 4. Brain Mapping: Jennifer Mundale. 5. Cognitive Anthropology: Charles W. Nuckolls. 6. Cognitive and Linguistic Development: Adele Abrahamsen. 7. Conceptual Change: Nancy J. Nersessian. 8. Conceptual Organization: Douglas Medin and Sandra R. Waxman. 9. Consciousness: Owen Flanagan. 10. Decision Making: J. Frank Yates (...) and Paul A. Estin. 11. Emotions: Paul E. Griffiths. 12. Imagery and Spatial Representation: Rita E. Anderson. 13. Language Evolution and Neuromechanisms: Terrence W. Deacon. 14. Language Processing: Kathryn Bock and Susan M. Garnsey. 15. Linguistics Theory: D. Terence Langendoen. 16. Machine Learning: Paul Thagard. 17. Memory: Henry L. Roediger III and Lyn M. Goff. 18. Perception: Cees Van Leeuwen. 19. Perception: Color: Austen Clark. 20. Problem Solving: Kevin Dunbar. 21. Reasoning: Lance J. Rips. 22. Social Cognition: Alan J. Lambert and Alison L. Chasteen. 23. Unconscious Intelligence: Rhianon Allen and Arthur S. Reber. 24. Understanding Texts: Art Graesser and Pam Tipping. 25. Word Meaning: Barbara C. Malt. Part III: Methodologies of Cognitive Science:. 26. Artificial Intelligence: Ron Sun. 27. Behavioral Experimentation: Alexander Pollatsek and Keith Rayner. 28. Cognitive Ethology: Marc Bekoff. 29. Deficits and Pathologies: Christopher D. Frith. 30. Ethnomethodology: Barry Saferstein. 31. Functional Analysis: Brian Macwhinney. 32. Neuroimaging: Randy L. Buckner and Steven E. Petersen. 33. Protocal Analysis: K. Anders Ericsson. 34. Single Neuron Electrophysiology: B. E. Stein, M.T. Wallace, and T.R. Stanford. 35. Structural Analysis: Robert Frank. Part IV: Stances in Cognitive Science:. 36. Case-based Reasoning: David B. Leake. 37. Cognitive Linguistics: Michael Tomasello. 38. Connectionism, Artificial Life, and Dynamical Systems: Jeffrey L. Elman. 39. Embodied, Situated, and Distributed Cognition: Andy Clark. 40. Mediated Action: James V. Wertsch. 41. Neurobiological Modeling: P. Read Montague and Peter Dayan. 42. Production Systems: Christian D. Schunn and David Klahr. Part V: Controversies in Cognitive Science:. 43. The Binding Problem: Valerie Gray Hardcastle. 44. Heuristics and Satisficing: Robert C. Richardson. 45. Innate Knowledge: Barbara Landau. 46. Innateness and Emergentism: Elizabeth Bates, Jeffrey L. Elman, Mark H. Johnson, Annette Karmiloff-Smith, Domenico Parisi, and Kim Plunkett. 47. Intentionality: Gilbert Harman. 48. Levels of Explanation and Cognition Architectures: Robert N. McCauley. 49. Modularity: Irene Appelbaum. 50. Representation and Computation: Robert S. Stufflebeam. 51. Representations: Dorrit Billman. 52. Rules: Terence Horgan and John Tienson. 53. Stage Theories Refuted: Donald G. Mackay. Part VI: Cognitive Science in the Real World:. 54. Education: John T. Bruer. 55. Ethics: Mark L. Johnson. 56. Everyday Life Environments: Alex Kirlik. 57. Institutions and Economics: Douglass C. North. 58. Legal Reasoning: Edwina L. Rissland. 59. Mental Retardation: Norman W. Bray, Kevin D. Reilly, Lisa F. Huffman, Lisa A. Grupe, Mark F. Villa, Kathryn L. Fletcher, and Vivek Anumolu. 60. Science: William F. Brewer and Punyashloke Mishra. Selective Biographies of Major Contributors to Cognitive Science: William Bechtel and Tadeusz Zawidzki. (shrink)

One of the most influential of the Victorian philosophers, Henry Sidgwick also made important contributions to fields such as economics, political theory and classics. A proponent of the utilitarianism of Jeremy Bentham and John Stuart Mill, which he analysed in his classic work The Methods of Ethics , he later turned to the practical side of politics in this work, published in 1891. His aim was to have a 'rational discussion of political questions in modern states', and he offers (...) a thorough examination of Victorian politics, beginning with a discussion of political theory before moving on to more concrete matters such as property and law. The later chapters discuss the function of government through themes such as procedural matters, international affairs, war, political parties, and public participation, giving a comprehensive account of both ideas about and the functioning of late-nineteenth-century government. (shrink)

We investigate under what conditions contrary-to-duty (CTD) structures lacking temporal and action elements can be given a coherent reading. We argue, contrary to some recent proposals, that CTD is not an instance of defeasible reasoning, and that methods of nonmonotonic logics are inadequate since they are unable to distinguish between defeasibility and violation of primary obligations. We propose a semantic framework based on the idea that primary and CTD obligations are obligations of different kinds: a CTD obligation pertains to, or (...) pre-supposes, a certain context in which a primary obligation is already violated. This framework is presented initially as an extension of Standard Deontic Logic (SDL), a normal modal logic of type KD, and is illustrated by application to a series of examples. The concluding section is concerned with some resemblances between CTD and defeasible reasoning. We show first that the SDL-based framework contains a flaw and must be adjusted. A discussion of possible adjustments, including an alternative treatment in terms of a preference-based semantics, reveals difficulties that are reminiscent of problems in defeasible reasoning and intensional accounts of defeasible conditionals. (shrink)

In this book, Alison Laywine considers the mystery of the Transcendental Deduction in Immanuel Kant's Critique of Pure Reason. What is it supposed to accomplish and how? Laywine argues that Kant's peculiar adaptation of his early account of a world is the key to this mystery. Collecting evidence from the Critique and other writings by Kant--in order to identify what he took himself to be doing on his own terms--she holds that Kant deliberately adapted elements of his early metaphysics (...) both to set the agenda of the Deduction and to carry it out. Laywine highlights how the most important metaphysical element in Kant's thought was his early account of a world; a world is not just the sum-total of all substances created by God, but a whole unified by the universal laws of community prescribed by God that externally relate any given substance to all others. From this conception of a world, Kant then extracted a way to conceive key elements in the Deduction: experience as the whole of all possible appearances unified by the universal laws human understanding gives to nature. (shrink)

Most people will grant that we bear special moral obligations toward at least some nonhuman animals that we do not bear toward inanimate objects like stones, mountains, or works of art. These moral obligations are plausibly grounded in the fact that many if not all nonhuman animals share important psychological states and capacities with us, such as consciousness, suffering, and goal-directed behavior. But which of these states and capacities are really critical for a creature’s possessing moral status, and how can (...) we determine which animals do in fact have them? In this paper, I examine three main approaches to answering these questions. First are what I term consciousness-based approaches that tackles these questions by first asking which animals are conscious. Second are affective-state approaches that focus on identifying behavioural and physiological signatures of states like pain, fear, and stress. Finally, I consider what I call preference-based approaches whose focus is on the question of which organisms have robust motivational states. I examine the prospects and challenges—both theoretical and empirical—faced by these seemingly contrasting methodologies. I go on to suggest that there are reasons why, despite challenges, we should be robustly committed to the project of identifying psychological grounds of moral status. I conclude by suggesting we should also take seriously the idea of pluralism about moral status, according to which each of these approaches might be capable of providing independent grounds for moral consideration. (shrink)

Some have argued that panpsychism offers the most simple view of reality. The most prominent advocate of this argument is Philip Goff. In this paper, I examine Goff’s position and argue that considerations of simplicity and parsimony do not support panpsychism. Quite the reverse: they give us good reason to reject it.

In lieu of an abstract, here is a brief excerpt of the content:Kant's Critique of Berkeley HENRY E. ALLISON THE CLAIMTHAT KANT'S IDEALISM,or at least certain strands of it, is essentially identical to that of Berkeley has a long and distinguished history. It was first voiced by several of Kant's contemporaries such as Mendelssohn, Herder, Hamann, Pistorius and Eberhard who attacked the alleged subjectivism of the Critique of Pure Reason. 1 This viewpoint found its sharpest contemporary expression in the (...) notorious Garve-Feder review to which Kant responded at length in the Prolegomena. In subsequent times it has been championed by Schopenhauer, and most nineteenth century German commentators on the relation between the two philosophers. 2 In addition, it has been, and continues to be, the prevailing view of the vast majority of British writers on Kant, including, with significant qualifications, Norman Kemp Smith. 3 This tradition continues despite the fact that Kant specifically, and in no uncertain terms, repudiated this identification in the Prolegomena and the second edition of the Critique. In both works he responds to the charges of subjectivism, and in so doing distinguishes his position from that of Berkeley, who in the eighteenth century was commonly regarded as a solipsist and denier of the "external world." 4 In contra-distinction to Kant's own critical or transcendental idealism, which explains the possibility of synthetic a priori knowledge within the realm of possible experience, Berkeley is characterized as a "dogmatic" or "visionary idealist." He is judged guilty of "degrading bodies to mere illusion" (B69), of regarding things in space as "merely imaginary entities" (B274), and of holding with all "genuine idealists" that: "all knowledge through the senses and experience is i Cf. Hans Vaihinger, Commentar zu Kant's Kritik der Reinen Vernunft (Stuttgart, Berlin, Leipzig, 1892), II, 494-505. Cf. Friederich Fredericks, Der Phainomenale Idealisraus Berkeley's und Kant's (Berlin, 1871); Robert Zimmerman, "Ober Kant's Widerlegung des Idealismus yon Berkeley" (Sitzungsberichte der Akademie der Wissenschaften, Vienna, Philox.-hist. Kl.), LXVIII (1871); Gustav Dieckert, tiber dos Verhiiltnis des Berkeleyschen ldealismus zu Kantischen Vernun]tkritik (Konitz, 1888). Tiffs is a consequence of the general British tendency to view Kant in phenomenalist terms. A typical recent example is found in P. F. Strawson, The Bounds of Sense (London, 1966). Kemp Smith in his Commentary to Kant's Critique o[ Pure Reason (2nd ed., rev., 1923) takes greaZ pains to distinguish between the subjectivist strand in Kant's thought, which is essentially identical to Berkeley's position, and the genuine critical doctrine which stands side by side with it in the text. 9 Cf. I-I.M. Bracken, The Early Reception of Berkeley's Materialism 1710-1733, rev. ed. (The Hague: Martinus Nijhoff, 1965). [43] 44 HISTORY OF PHILOSOPHY nothing but sheer illusion, and only in the ideas of pure understanding is there truth" (374). 5 One of the chief reasons for the continuation of the Kant-Berkeley tradition is that these, and similar statements about Berkeley, which we find in these works and in Kant's correspondenc e with Beck, have not been taken very seriously by Kant's critics. They are usually dismissed as obvious misinterpretations, due to Kant's ignorance of Berkeley's actual writings, and of his reliance upon distorted second and third hand accounts of Berkeley's thought such as is to be found in Beattie. Furthermore, this view is often supported by the philological reflection that Kant did not read English, and that Berkeley's writings were not yet available in German translation. 6 The philological argument, however, loses much of its force when we consider that there was indeed a German translation of Berkeley's Dialogues, which although apparently unknown to nineteenth century scholars, was readily accessible to Kant. This is to be found, together with a translation of Collier's Clavis Universalis and critical analyses, in a work by the professor of philosophy at Rostock, Johann Christian Eschenbach, entitled: Samlung der vornehmsten Schri[tsteller die die tFirklichkeit ihres eignen K~rpers und der ganzen Ki~rperwelt leugnen (Rostock, 1756). Furthermore, in addition to this work, which was probably known to Kant, there is Berkeley's important Latin work, De Motu (1721), as well as French translations of many of... (shrink)

Raz's method is as unusual, and as admirable, as the substance of his sometimes rather unfortunately labeled "perfectionist liberalism"—unfortunate because "it is not perfectionist in the more ordinary sense of the term" in that it recognizes that "imperfect ways of life may be the best which is possible for people" and "is strongly pluralistic", while understanding its fundamental value of well-being as the active and autonomous making of a life of one's own. Raz's approach is simultaneously alert to the complexity (...) of argument, to a degree that practitioners of practical ethics sometimes are not, and aware of the limits of theorizing, as devotees of theoretical ethics rarely are. Thus, while scorning "supermarket liberalism" and rejecting, in company with Rawls, "hand-to-mouth piecemeal intuitionism", Raz also doubts whether ideal theory in the Rawlsian mode is "a meaningful enterprise", emphasizing wisely, in my judgment, that "not everything we know can be exhaustively stated in the abstract". The "dense webs of complex actions and interactions" that give meaning to our lives "defy explicit learning or comprehensive articulation. They are available only to those who have or can acquire practical knowledge of them, that is, knowledge embodied in social practices and transmitted by habituation". (shrink)

This is a reprint of the classic work by Henry Churchill King, "The Seeming Unreality of the Spiritual Life."At Oberlin College from 1884, he taught in mathematics, philosophy, and theology. From 1902 to 1927, he was president of the college. With a tenure of 25 years, is Oberlin's longest-serving president. In 1919, he served on the King-Crane Commission, whose recommendations on the fair and just disposition of non-Turkish areas of the Ottoman Empire might, had they been followed, would have (...) averted many of the tragedies that have come to pass in the Middle East since that time. The findings of that commission, suppressed until 1922, were finally made public in the King-Crane Commission Report and shed tremendous light on the wishes of the indigenous peoples of the region, as to who would be entrusted with the various mandates, the future of Palestine, and other vital issues.He was prominent in the councils of the Congregational Church and a moderator (1919-21) of its National Council as well as chairman (1921-27) of the Congregational Foundation for Education. (shrink)

Volume 19, Issue 6, June 2019, Page 19-21.

Many diseases and disease symptoms still lack effective treatment. At the same time, certain controversial Schedule I drugs, such as heroin and cannabis, have been reputed to have considerable therapeutic potential for addressing significant medical problems. Yet, there is a paucity of U.S. clinical studies on the therapeutic uses of controlled drugs. For example, people living with HIV/aids experience a variety of disease- and medication-related symptoms. Their chronic pain is intense, frequent, and difficult to treat. Nevertheless, clinical trials of compassionate (...) management for their chronic symptoms, which should be a research priority, are stymied. Stakeholders’ Views on Barriers to Research on Controlled Substances Evelyn Rhodes, Michael Andreae, Tyler Bourgiose, Debbie Indyk, Rosamond Rhodes, and Henry Sacks We employed qualitative methods to develop an understanding of the barriers to research on potential therapeutic uses of Schedule I drugs so that they might be addressed. We elicited the perspectives of key stakeholder groups that would be involved in such studies: people living with HIV/aids, clinicians, and members of institutional review boards. As we identified obstacles to research, we found that all of the stakeholder groups arrived at the same conclusion, that clinical research on the therapeutic potential of these drugs is ethically required. (shrink)

Response Content Type Journal Article Pages 215-216 DOI 10.1007/s11673-011-9296-0 Authors Henry Kilham, General Medicine and Clinical Ethics, The Children’s Hospital at Westmead, Westmead, NSW, Australia 2063 David Isaacs, The Centre for Values Ethics and the Law in Medicine, University of Sydney, Sydney, NSW, Australia 2006 Journal Journal of Bioethical Inquiry Online ISSN 1872-4353 Print ISSN 1176-7529 Journal Volume Volume 8 Journal Issue Volume 8, Number 2.

This chapter contains section titled: Alternatives to Mill's Methodology Conclusion.

Introduction: On trying to be an Aristotelian or a Thomist in today's world -- QUIETING VARIOUS OF THE ALARMS AND EXCURSIONS IN RECENT PHILOSOPHY: Can philosophy ever be a thing for Hoosiers? -- Folly and sense in present-day philosophy -- Is Quine a metaphysician? -- Richard Rorty's would-be deconstruction of analytic philosophy -- WHAT PRICE ETHICS IN THE EYES OF MODERN MORAL PHILOSOPHERS? : Telos and teleology in Aristotelian ethics -- Variations, good and bad, on the theme of right reason (...) in ethics -- Language and ethics: 'What's Hecuba to him, or he to Hecuba?' -- In appreciation and refutation of Alan Gewirth's principle of general consistency -- Ethical egoism, new style: should its trademark be libertarian or Aristotelian? -- A CONCLUDING MISCELLANY, RANGING FROM A DEFENSE OF THE HUMANITIES TO A DEFENSE OF NATURAL LAW: The what and why of the humanities -- Why need a general be human? -- The poor, hapless humanities -- Natural law: dead or alive? -- Can John Finnis bright of a revival of natural law? -- Natural law and the"is"-"ought" question: queries to Finnis and Grisez -- A poor benighted philosopher looks at the issue of judicial activism / Henry B. Veach. (shrink)

The most striking region of structural differentiation of a eukaryotic chromosome is the kinetochore. This chromosomal domain plays an integral role in the stability and propagation of genetic material to the progeny cells during cell division. The DNA component of this structure, which we refer to as the centromere, has been localized to a small region of 220–250 base pairs within the chromosomes from the yeast Saccharomyces cerevisiae. The centromere DNA (CEN) is organized in a unique structure in the cell (...) nucleus and is required for chromosome stability during both mitotic and meiotic cell cycles. The centromeres from one chromosome can stabilize small circular minichromosomes or other yeast chromosomes. The centromeres may therefore interact with the same components of the segregation apparatus regardless of the chromosome in which they reside. The CEN DNA does not encode any regulatory RNAs or proteins, but rather is a cis‐acting element that provides genetic stability to adjacent DNA sequences. (shrink)

In this paper we describe the development and initial psychometric evaluation of a new measure, the values in scientific work. This scale assesses the level of importance that investigators attach to different VSW. It taps a broad range of intrinsic, extrinsic, and social values that motivate the work of scientists, including values specific to scientific work and more classic work values in the context of science. Notably, the values represented in this scale are relevant to scientists regardless of their career (...) stage and research focus. We administered the VSW and a measure of global values to 203 NIH-funded investigators. Exploratory factor analyses suggest the delineation of eight VSW, including autonomy, research ethics, social impact, income, collaboration, innovation and growth, conserving relationships, and job security. These VSW showed predictable and distinct associations with global values. Implications of these findings for work on research integrity and scientific misconduct are discussed. (shrink)

One of the great merits ofOn Complicity and Compromiseis that it wades into specific swamps where ordinary theorists fear to slog. It is persuasive that in general it can be right sometimes to be complicit in wrongdoing by others through causally contributing to the wrongdoing, but not sharing its purpose, if by being involved one can reasonably expect to lessen the extent of the wrong that would otherwise be suffered by the victims. I focus on whether the book's general thesis (...) is applicable to torture, which depends on what torture and the torture situation are in fact like. I focus on the case to which the chapter several times refers: the innovative CIA paradigm of torture. First, to the extent that the paradigm, which is predominantly mental, or psychological, torture succeeds in its goal of producing regression to a compliant state, the physician would be unable to rely on the torture victim's expressions of preferences or interests as authentically his own. Second, since disorientation plays such a large role in the CIA's style of torture (adopted at Guantanamo by the military), the authorities would refuse to allow a stable relationship to be built up with any one doctor by any victim, making comprehension of the victim's preferences difficult. Third, even if the doctor could somehow judge what the victim's genuine interests were, the control of the situation is much too totalistic to allow the physician any action independent of what the torture regime requires. (shrink)