Clinical trials emerged in rapid succession as the COVID-19 pandemic created an unprecedented need for life-saving therapies. Fair and equitable subject selection in clinical trials offering investigational therapies ought to be an urgent moral concern. Subject selection determines the distribution of risks and benefits, and impacts the applicability of the study results for the larger population. While Research Ethics Committees monitor fair subject selection within each trial, no standard oversight exists for subject selection across multiple trials for the same disease. (...) Drawing on the experience of multiple clinical trials at a single academic medical centre in the USA, we posit that concurrent COVID-19 trials are liable to unfair and inequitable subject selection on account of scientific uncertainty, lack of transparency, scarcity and, lastly, structural barriers to equity compounded by implicit bias. To address the critical gap in the current literature and international regulation, we propose new ethical guidelines for research design and conduct that bolsters fair and equitable subject selection. Although the proposed guidelines are tailored to the research design and protocol of concurrent trials in the COVID-19 pandemic, they may have broader relevance to single COVID-19 trials. (shrink)

Objective: Illness perceptions are important predictors of emotional and behavioral responses in many diseases. The current study aims to investigate the COVID-19-related IP throughout Europe. The specific goals are to understand the temporal development, identify predictors and examine the impacts of IP on perceived stress and preventive behaviors.Methods: This was a time-series-cross-section study of 7,032 participants from 16 European countries using multilevel modeling from April to June 2020. IP were measured with the Brief Illness Perception Questionnaire. Temporal patterns were observed (...) considering the date of participation and the date recoded to account the epidemiological evolution of each country. The outcomes considered were perceived stress and COVID-19 preventive behaviors.Results: There were significant trends, over time, for several IP, suggesting a small decrease in negativity in the perception of COVID-19 in the community. Age, gender, and education level related to some, but not all, IP. Considering the self-regulation model, perceptions consistently predicted general stress and were less consistently related to preventive behaviors. Country showed no effect in the predictive model, suggesting that national differences may have little relevance for IP, in this context.Conclusion: The present study provides a comprehensive picture of COVID-19 IP in Europe in an early stage of the pandemic. The results shed light on the process of IP formation with implications for health-related outcomes and their evolution. (shrink)

The commitment of transplant physicians to protect the physical and psychological health of potential donors is fundamental to the process of living donor organ transplantation. It is appropriate that strict regulations to govern an individual’s decision to donate have been developed. Some may argue that adherence to such regulations creates a doctor-patient relationship that is rooted in paternalism, which is in drastic contrast with a doctor-patient relationship that is rooted in patients’ autonomy, characteristic of most other operative interventions.In this article (...) we analyze the similarities between cosmetic plastic surgery and living donor surgery as examples of surgeries governed by different ethical principles. It is interesting that, while the prevailing ethical approach in living donor surgery is based on paternalism, the ethical principle guiding cosmetic surgery is respect for patients’ autonomy. The purpose of this article is not to criticize either practice, but to suggest that, given the similarities between the two procedures, both operative interventions should be guided by the same ethical principle: a respect for patients’ autonomy. We further suggest that if living organ donation valued donors’ autonomy as much as cosmetic plastic surgery does, we might witness a wider acceptance of and increase in living organ donation. (shrink)

This article investigates the concept of sound, in relation to the new means and sciences from different perspectives, ultimately providing an analysis of the newborn artistic movement of bioart. It is divided into two parts. The first part of the study is based upon reference, investigating the interconnection between art and science. This mechanism is characterized by transformation processes in the interdisciplinary practices that are applied mainly by various artists and movements of the post-Second World War period. The expressive element (...) seeks an unworldly explanation through audio and visual conjunctions. This nature is obvious in Paul Klee’s reflections of musical elements in his paintings, and Rimmington’s attempts to marry audio-visual influences in his ‘colour organs’. The experimentations of composers such as Xenakis and Stockhausen at various locations with light and colour illustrate the continuous quest to render sound by the use of new means. Technology is a vital component of transformation as it enhances syncretic creativity for various art domains such as those that Fluxus deployed. Nam Jun Paik and Dick Higgins introduce radical techniques in their performances as they detach their selves from the parameters that define composition, and use the mind and power of sentiment in order to identify reality aurally and optically. Towards the end of the twentieth century, we witnessed the appearance of new art forms such as bioart. The human body, host of material and immaterial functions, comes to the forefront of art prac¬tice. Its relation to elements such as oscillations and vibrations that express the energy flow is analysed through the model of spiritualism that came from eastern thought. The notion of digital embodiment is presented as a reminder, highlight¬ing the importance of technology in biotechnology and genetics. The second part of the article involves an experiment. This describes how the concept of biomusic is applied with the use of electrocardiography (ECG) data from the MIT PhysioNet database. As sound penetrates the entire human body, it can be analysed in all of its phasma. Using this information, we attempt to translate/transform these biological sound phenomena into music. The sound produced by the elaboration of data that result from biological functions can be described as biomusic. It can be transformed into frequencies related to time and can be expressed in musical themes. Sonification plays an important role in this research as it constitutes a rapid and precise rendering of polymorphic information (in this case the ECG) in musical notes. This modelling and musical attribution leads to two distinguishable results, each concerning different clinical cases (all data belong to a normal heart function and a pathological one). The invention of this novel system is suggested for scientific as well as musical disciplines. It has the ability to be implemented in an experimental form and obtain an educational character. The transformation process avoids compensation throughout the matching process between ECG functions and music, while focusing on the aesthetic factor at the same time. Sound meets art in the world of biomusic as it takes shape through technology, constituting a new medium to further evolve the model of ‘biology into art’ transformation. (shrink)

The coronavirus disease pandemic fundamentally disrupted humans’ social life and behavior. Public health measures may have inadvertently impacted how people care for each other. This study investigated prosocial behavior, its association well-being, and predictors of prosocial behavior during the first COVID-19 pandemic lockdown and sought to understand whether region-specific differences exist. Participants from eight regions clustering multiple countries around the world responded to a cross-sectional online-survey investigating the psychological consequences of the first upsurge of lockdowns in spring 2020. Prosocial behavior (...) was reported to occur frequently. Multiple regression analyses showed that prosocial behavior was associated with better well-being consistently across regions. With regard to predictors of prosocial behavior, high levels of perceived social support were most strongly associated with prosocial behavior, followed by high levels of perceived stress, positive affect and psychological flexibility. Sociodemographic and psychosocial predictors of prosocial behavior were similar across regions. (shrink)

Considering the high impact strain that the severe acute respiratory syndrome coronavirus 2 pandemic has put on medical personnel worldwide, identifying means to alleviate stress on healthcare professionals and to boost their subjective and psychological wellbeing is more relevant than ever. This study investigates the extent to which the relationships between the status of working in healthcare and the subjective and psychological wellbeing are serially mediated by work recovery experiences and the need for recovery. Data were collected from 217 Romanian (...) employees using a cross-sectional design with self-report instruments, during the first stage of the nationwide lockdown. The results of the serial mediation analyses revealed that working in the medical field is indirectly related to subjective and psychological wellbeing through the following: mastery experiences and mastery experiences as an antecedent of the need for recovery. As such, our findings indicate that working in the medical field is, in fact, linked to healthcare professionals’ subjective and psychological wellbeing, and they provide some input on how recovery experiences and the need for recovery intervene in these relationships. Based on these findings, theoretical, methodological, and practical implications were suggested, and future research directions were proposed to maximize healthcare professionals’ wellbeing. (shrink)

The authors present the preliminary publication of seven hitherto unpublished inscriptions from the Roman colony at Philippi in the province of Macedonia. These inscriptions make known a number of new notables who were active in the colony during the 1st and 2nd centuries AD. Amongst them is a soldier from Philippi who had pursued a career in the cohortes vigilae in Rome, as well as several municipal magistrates and seviri augusti from Philippi. All the inscriptions connected with the institutions of (...) the colony, and also those mentioning members of the senatorial and equestrian orders and soldiers, will shortly be included in the first volume of the Corpus of Greek and Latin Inscriptions of Philippi. The assembling of the epigraphic material relating to the municipal and imperial administration of Philippi, enriched by numerous unpublished inscriptions, will enable us to renew our acquaintance with the social and political structures of the colony. (shrink)

Ayahuasca is a hallucinogenic plant mixture used in a ceremonial context throughout western Amazonia, and its use has expanded globally in recent decades. As part of this expansion, ayahuasca has become popular among westerners who travel to the Peruvian Amazon in increasing numbers to experience its reportedly healing and transformative effects. Drawing from ethnographic fieldwork in and around the area of Iquitos, Peru, the epicenter of ayahuasca tourism, this paper focuses on some of the problematic aspects of western engagement with (...) indigenous spiritual traditions. This engagement is usually based on idealized and romanticized notions of indigenous shamanism and an inability to digest its less palatable aspects, such as sorcery. Through ethnographic examples and ethnohistorical evidence, I show that the romanticization indigenous peoples is not benign. In fact, this one-sided romantic image hides the complexity of indigenous peoples’ situations by erasing the injustices that they have experienced and continue to experience. I propose a more holistic approach to ayahuasca shamanism that views indigenous peoples not living in a fictitious harmony with nature but as people embedded in larger struggles and facing important challenges not the least of which is the recent commercialization of indigenous spirituality. (shrink)

In this article, I discuss how ritual is framed in the context of ayahuasca tourism, using ethnographic data collected in and around Iquitos, Peru. Alluding to a lack of socially sanctioned spaces for altered states of consciousness (ASCs) in western cultures, contemporary seekers flock to the Amazon to participate in ayahuasca ceremonies for an array of reasons, including healing and personal transformation. Taking Gregory Bateson's concept of “framing” as a point of departure, and applying Erving Goffman's frame analysis, I will (...) show that contemporary ayahuasca ceremonies attended by westerners are designed to be liminal, transformative, and meaningful experiences that aim to heal the body through emotional modulation. I will demonstrate how this is achieved through specific discourse that takes place before or during rituals in the form of long speeches delivered by the shamans. This framing not only separates the ritual space as liminal but also frames the way that the experience is conceptualized by the participants, ultimately increasing its meaningfulness. (shrink)

In this study, we explore the relation between scientific literacy and unwarranted beliefs. The results show heterogeneous interactions between six constructs: conspiracy theories poorly interact with scientific literacy; there are major differences between attitudinal and practical dimensions of critical thinking; paranormal and pseudoscientific beliefs show similar associations ; and, only scientific knowledge interacts with other predictor of unwarranted beliefs, such as ontological confusions. These results reveal a limited impact: science educators must take into account the complex interactions between the dimensions (...) of scientific literacy and different types of unwarranted beliefs to improve pedagogical strategies. (shrink)

We study probabilistically informative (weak) versions of transitivity by using suitable definitions of defaults and negated defaults in the setting of coherence and imprecise probabilities. We represent p-consistent sequences of defaults and/or negated defaults by g-coherent imprecise probability assessments on the respective sequences of conditional events. Moreover, we prove the coherent probability propagation rules for Weak Transitivity and the validity of selected inference patterns by proving p-entailment of the associated knowledge bases. Finally, we apply our results to study selected probabilistic (...) versions of classical categorical syllogisms and construct a new version of the square of opposition in terms of defaults and negated defaults. (shrink)

Nella seconda metà del Novecento la conoscenza dell'etica anglosassone in Italia è stata alquanto parziale. Si pensava che il mondo dell'etica di lingua inglese fosse stato dominato nel Novecento dallo scientismo neopositivista o pragmatista che non riusciva a concepire l'etica se non nella forma tecnicizzata dell'analisi del linguaggio o metaetica. In questo modo si è ignorata tutta una ripresa dell'etica normativa, in particolare di Kant e di Aristotele, o la ripresa del diritto naturale che ha tra i suoi principali riferimenti (...) storici il pensiero di Tommaso d'Aquino intorno alla legge. Questo volume presenta un quadro della filosofia pratica anglosassone degli ultimi cinquant'anni. (shrink)

Limited health literacy is a pervasive and independent risk factor for poor health outcomes. Despite decades of reports exhibiting that the healthcare system is overly complex, unneeded complexity remains commonplace and endangers the lives of patients, especially those with limited health literacy. In this article, we define health literacy and describe the empirical evidence associating health literacy and poor health outcomes. We recast the issue of poor health literacy from within the ethical perspective of the least well-off and argue that (...) poor health outcomes deriving from limited health literacy ought to be understood as a fundamental injustice of the healthcare system. We offer three proposals that attempt to rectify this injustice, including: universal precautions that presume limited health literacy for all healthcare users; expanded use of technology supported communication; and clinical incentives that account for limited health literacy. (shrink)

In view of the arguments put forward by Clifton and Monton [this volume], we reconsider the alleged conflict of dynamical reduction models with the enumeration principle. We prove that our original analysis of such a problem is correct, that the GRW model does not meet any difficulty and that the reasoning of the above authors is inappropriate since it does not take into account the correct interpretation of the dynamical reduction theories.

Analyzing Social Knowledge argues for both socialized and naturalized epistemology. J. Angelo Corlett takes social epistemology in a new direction, applying the findings of experimental cognitive psychology to theories of social knowledge. Corlett analyzes social knowlegde in terms of group belief, individual belief, truth, justification, coherence, and reliability and responsibility. He provides a critique of leading theories of social knowledge and defends his analysis against respected criticisms of naturalized epistemology. The far-reaching implications of Analyzing Social Knowledge will interest epistemoloogists, philosophers (...) of the mind, and cognitive psychologists. (shrink)

In this paper we consider conditional random quantities (c.r.q.’s) in the setting of coherence. Based on betting scheme, a c.r.q. X|H is not looked at as a restriction but, in a more extended way, as \({XH + \mathbb{P}(X|H)H^c}\) ; in particular (the indicator of) a conditional event E|H is looked at as EH + P(E|H)H c . This extended notion of c.r.q. allows algebraic developments among c.r.q.’s even if the conditioning events are different; then, for instance, we can give a (...) meaning to the sum X|H + Y|K and we can define the iterated c.r.q. (X|H)|K. We analyze the conjunction of two conditional events, introduced by the authors in a recent work, in the setting of coherence. We show that the conjoined conditional is a conditional random quantity, which may be a conditional event when there are logical dependencies. Moreover, we introduce the negation of the conjunction and by applying De Morgan’s Law we obtain the disjoined conditional. Finally, we give the lower and upper bounds for the conjunction and disjunction of two conditional events, by showing that the usual probabilistic properties continue to hold. (shrink)

A standard view in social science and philosophy is that a lie is a dishonest assertion: to lie is to assert something that you think is false in order to deceive your audience. We report four behavioral experiments designed to evaluate some aspects of this view. Participants read short scenarios and judged several features of interest, including whether an agent lied. We found evidence that ordinary lie attributions can be influenced by aspects of audience uptake, are based on judging that (...) the agent made an assertion (assertion attributions), and, at least in some contexts, are not based on attributions of deceptive intent. The finding on assertion attributions is predicted by the standard view, but the finding on intent attributions is not. These results help to further clarify the ordinary concept of lying and shed light on the psychological processes involved in ordinary lie attributions and related judgments. (shrink)

The grounding of symbols in computational models of linguistic abilities is one of the fundamental properties of psychologically plausible cognitive models. In this article, we present an embodied model for the grounding of language in action based on epigenetic robots. Epigenetic robotics is one of the new cognitive modeling approaches to modeling autonomous mental development. The robot model is based on an integrative vision of language in which linguistic abilities are strictly dependent on and grounded in other behaviors and skills. (...) It uses simulated robots that learn through imitation the names of basic actions. Robots also learn higher order action concepts through the process of grounding transfer. The simulation demonstrates how new, higher order behavioral abilities can be autonomously built on previously grounded basic action categories following linguistic interaction with human users. (shrink)

Abstract. I argue that pessimistic meta-induction (PMI) seems to point an ontological priority of the relations over the objects of the scientific theories of the kind suggested by French and Ladyman (French and Ladyman 2003). My strategy will involve a critical examination of epistemic structural realism (ESR) and historical case-study: the prediction of Zeeman’s effect in Lorentz’s theory of electron.

This paper aims to conceptualize the phenomenology of attentional experience as ‘embodied attention.’ Current psychological research, in describing attentional experiences, tends to apply the so-called spotlight metaphor, according to which attention is characterized as the illumination of certain surrounding objects or events. In this framework, attention is not seen as involving our bodily attitudes or modifying the way we experience those objects and events. It is primarily conceived as a purely mental and volitional activity of the cognizing subject. Against this (...) view, the phenomenology of Maurice Merleau-Ponty shows that attention is a creative activity deeply linked with bodily movements. This paper clarifies and systematizes this view and brings it into dialogue with current empirical findings as well as with current theoretical research on embodied cognition. By doing this, I spell out three main claims about embodied attention: the transcendentalism of embodiment for attention, the bodily subjectivity of attention, and the creativity of embodied attention. (shrink)

We provide a new wrinkle to the Argument from Unfair Advantage, a rather popular one in the ethics of doping in sports discussions. But we add a new argument that we believe places the moral burden on those who favor doping in sports. We also defend our position against some important concerns that might be raised against it. In the end, we argue that for the time being, doping in sports ought to be banned until it can be demonstrated that (...) our concerns can be satisfied. (shrink)

Over and above the modalities with which it is expressed in the domains of Kant’s system, the theme of cosmopolitanism embodies the meaning of a philosophy seen as a plan to build on the connection between man, polis and reason; an essential connection that in human reason identifies not a simple endowment which everyone has by nature but a form of life to be realized in the world, a purpose whose binding strength is only fully expressed in the public dimension.

‘Epistemic structural realism’ (ESR) insists that all that we know of the world is its structure, and that the ‘nature’ of the underlying elements remains hidden. With structure represented via Ramsey sentences, the question arises as to how ‘hidden natures’ might also be represented. If the Ramsey sentence describes a class of realisers for the relevant theory, one way of answering this question is through the notion of multiple realisability. We explore this answer in the context of the work of (...) Carnap, Hintikka and Lewis. Both Carnap and Hintikka offer clear structuralist perspectives which, crucially, accommodate the openness inherent in theory change. Unfortunately there is little purchase for a viable form of realism in either case. Lewis’s approach, on the other hand, offers more scope for realism but, as we shall see, concerns arise as to whether a relevant form of structuralism can be maintained. In particular his thesis of Ramseyan humility undermines certain conceptions of scientific laws that the structural realist might naturally cleave to. Our overall conclusion is that the representational device of Ramsey sentence plus multiple realisability can accommodate either the structuralist or realist aspects of ESR but has difficulties capturing both. (shrink)

In this interview for the TCS website, Angelo Martins Jr interviews Professor Julia O’Connell Davidson about her recent book, Modern Slavery: The Margins of Freedom (2015). The interview further discusses some of the most prominent (and often controversial) topics examined by O’Connell Davidson’s book, such as her understanding of modern slavery and her critique on (and consequences of) how anti-slavery movements, NGOs and right-wing and social democratic media and politicians have mistakenly appropriated and used the term. The interview further considers (...) some of the global contemporary social, political and economic issues, such as ‘the refugee crisis’, border control, citizenship and global socio-economic inequalities. (shrink)

The aim of this article is to investigate around the life in the contemporary society, characterized by risks and catastrophes. What does mean to live fearing that in any moment a catastrophe could happen (a tsunami, an earthquake, a nuclear explosion)? Despite of the failure of science and public institutions in the prevention of the catastrophes, the question is the following: Can we use the catastrophe as a paradigm of the contemporary uncertain life, trying to mean it as a theme (...) of mediation? Can we use the catastrophe for developing a philosophy of the recognition of the other who has been involved in the same tragedy? (shrink)

Bernard Berenson used to refer to Giovanni Morelli as «the founder of the Method». With these words, he meant that Morelli was the scholar who, first, transformed connoisseurship in a science, giving to the discipline a stringent method. Does Morelli’s theory of painting really deserve this praise? To answer this question, this paper examines in the first part the philosophical and scientific background of Morelli’s doctrine, showing how its original debt payed to romantic philosophy went replaced by a neat positivist (...) orientation. In the second part, the Method itself is discussed, asking in which measure it was anticipated by the intuitions of art experts such as Giulio Mancini or Luigi Crespi and discussing the nature and epistemological relevance of the so-called “morellian details”, that is the forms of the nails, of the ears, of the hair’s curls in paintings. Are these details really sufficient for the attribution of a painting to an artist? Which role play the documents in connoisseurship? And, more generally, how important is aesthetic value in the morellian “Method”? (shrink)