Retinopathy of prematurity (ROP) is a complex neonatal disorder with multiple contributing factors. In this paper we have mounted the evidence in support of the proposal that neonatal sepsis meets all requirements for being a cause of ROP (not a condition, mechanism, or even innocent bystander) by means of initiating the early stages of the pathomechanism of ROP occurrence, systemic inflammation. We use the model of etiological explanation, which distinguishes between two overlapping processes in ROP causation. It can be shown (...) that sepsis can initiate the early stages of the pathomechanism via systemic inflammation (causation process) and that systemic inflammation can contribute to growth factor aberrations and the retinal characteristics of ROP (disease process). The combined contribution of these factors with immaturity at birth (as intrinsic risk modifier) and prenatal inflammation (as extrinsic facilitator) seems to provide a cogent functional framework of ROP occurrence. Finally, we apply the Bradford Hill heuristics to the available evidence. Taken together, the above suggests that neonatal sepsis is a causal inducer of ROP. (shrink)

Reinforcement schemes are a class of non-Markovian stochastic processes. Their non-Markovian nature allows them to model some kind of memory of the past. One subclass of such models are those in which the past is exponentially discounted or forgotten. Often, models in this subclass have the property of becoming trapped with probability 1 in some degenerate state. While previous work has concentrated on such limit results, we concentrate here on a contrary effect, namely that the time to become trapped may (...) increase exponentially in 1/x as the discount rate, 1− x, approaches 1. As a result, the time to become trapped may easily exceed the lifetime of the simulation or of the physical data being modeled. In such a case, the quasi-stationary behavior is more germane. We apply our results to a model of social network formation based on ternary (three-person) interactions with uniform positive reinforcement. (shrink)

© The Author 2017. Published by Oxford University Press on behalf of The Analysis Trust. All rights reserved. For Permissions, please email: [email protected] article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model...The editors of this interesting collection,1 Stephan Blatti and Paul Snowdon, have placed the various essays, most of which were specially written for this volume, in three categories: Part I contains articles critical of animalism; Part II contains essays defending animalism and (...) Part III contains essays drawing out the consequences and practical applications of animalism. After some introductory remarks, I will discuss two of the essays attacking animalism – those of Derek Parfit and Mark Johnston – and then comment on Paul Snowdon’s essay....First, though, a word on the definition of animalism. In their Introduction, Blatti and Snowdon define animalism as ‘… the... (shrink)

Where does entertaining (or promoting) conspiracy theories stand with respect to rational inquiry? According to one view, conspiracy theorists are open-minded skeptics, being careful not to accept uncritically common wisdom, exploring alternative explanations of events, no matter how unlikely they might seem at first glance. Seen this way, they are akin to scientists attempting to explain the social world. On the other hand, they are also sometimes seen as overly credulous, believing everything they read on the internet, say. In addition (...) to conspiracy theorists and scientists, another significant form of explanation of the events of the world can be found in religious contexts, such as when a disaster is explained as being an “act of God.” By comparing conspiratorial thinking with scientific and religious forms of explanation, features of all three are brought into more clear focus. For example, anomalies and a commitment to naturalist explanation are seen as important elements of scientific explanation, although the details are less clear. This paper uses conspiracy theories as a lens through which to investigate rational or scientific inquiry. In addition, a better understanding of the scientific method as it might be applied in the study of events of interest to conspiracy theorists can help understand their epistemic virtues and vices. (shrink)

Since its publication in 1965, Brian Barry's seminal work has occupied an important role in the revival of Anglo-American political philosophy. A number of ideas and terms in it have become part of the standard vocabulary, such as the distinction between "ideal-regarding" and "want-regarding" principles and the division of principles into aggregative and distributive. The book provided the first precise analysis of the concept of political values having trade-off relations and its analysis of the notion of the public interest (...) has also been significant. (shrink)

Volume 19, Issue 10, October 2019, Page 112-114.

First published in 1979, this book considers the culture of a multi-racial community through the eyes of six children about to start school. Each child is from a different background but all live in the same street in a town in the north of England. Following the children from home into school, their six separate lives are unveiled, illustrating the manner in which their six separate worlds are in some ways grounded in their own respective cultures, and in others interwoven (...) with the common experience of school. These Children enter school in search of a multi-cultural society, and a sympathetic appraisal is made of what happens to them as they face such initially daunting prospects as the classroom, television and the playground. The most compelling element in this book is the way in which education is shown to be able to derive benefit from this cultural diversity. The research was commissioned by the Social Sciences Research Council and the Leverhulme Trust, and will be of particular interest to those working in social work and education. (shrink)

The cumulative case for specifically Christian belief now concentrates on the history of Israel and the story of Jesus and its aftermath, including the rise of the Christian Church. Rational assessment of these historical facts depends greatly on the background beliefs already held. Theistic belief leads one to expect revelation. Sympathy towards revelation claims leads one to take seriously the historical evidence for the unique status claimed for Jesus Christ, including the evidence for his Resurrection. The work of David Brown (...) and Richard Swinburne on evidence for the Incarnation is assessed. (shrink)

It is commonly believed that the history of behavior that has contributed to the threat of climate change bears in a significant way on the obligations of current people. In particular, a number of philosophers have defended the Beneficiary Pays Principle, according to which those who have benefited from unjust emitting activity have a special obligation to bear costs of mitigation and adaptation. I claim that versions of the BPP that have been defended by others share a common problematic feature. (...) Specifically, they seem to limit the benefits that ground obligations under the principle to those that derive from unjust acts, and thereby implicitly deny that other ways in which individuals might benefit from injustice can ground similar duties. I argue that there is no plausible theoretical basis for this distinction. I conclude that we should take seriously a different type of principle that can be plausibly called a Beneficiary Pays Principle, according to which those who benefit from injustice, all things considered, are obligated to give up the unjust benefits that they enjoy. (shrink)

A philosophical analysis of the discourses, practices, and effects of representation in political institutions, focusing on American democracy.

Ernest Adams has claimed that a probabilistic account of validity gives the best account of our intuitive judgements about the validity of arguments. In particular, he claims, it has the best hope of accounting for our judgements about many arguments involving conditionals. Most of the examples in the literature on this topic have been arguments framed in the language of propositional logic. I show that once we consider arguments involving predicates and involving identity, Adams’s strategy is less successful.

Barrett and Artzenius posed a problem concerning infinite sequences of decisions. It appeared that the strategy of making the rational choice at each stage of the game was, in some circumstances, guaranteed to lead to lower returns than the strategy of making the irrational choice at each stage. This paper shows that there is only the appearance of paradox. The choices that Barrett and Artzenius were calling ‘rational’ cannot be economically justified, and so it is not surprising that someone who (...) makes them ends up with sub-optimal returns. A solution to the more general problem they pose is also advanced. (shrink)

Our primary interest this week will be in two objections Jackson mentions which seem to threaten his program. Each of them is avoided by appeal to the two-dimensional framework we sketched last week. Before we go over that framework again, we will start by looking at the objections. For reasons that may become apparent shortly, we will look at them in reverse order. So first we’ll look at this objection from Chapter 3, an objection which turns on the discovery of (...) a posteriori necessities by Kripke and Putnam. (shrink)

This paper argues that Boethius’ De Consolatione Philosophiae presents theoretical metaphysical speculation as having a direct bearing on the life of the metaphysician. Boethius accomplishes this through his depiction of Lady Philosophy’s ‘therapy’ wherein complex metaphysical arguments are utilized to pull Boethius out of his depression, returning him to what she calls his true self. I begin the paper by contextualizing this discussion in terms of the debate as to whether or not the ‘philosophic life’ of pagan antiquity is present (...) in medieval thought. I then turn to a discussion of the therapeutic metaphysical arguments of Lady Philosophy and their effects on Boethius’ mental and emotional state. I conclude the essay by listing some questions raised and directions for further study. (shrink)

Abstract.In the debates about legal determinacy, an important but often neglected issue is what is meant in the legal context by saying that a question has a right answer. By way of a critique of A. D. Woozley's discussion of “right answers,” I try to show how this issue is connected with issues of legal truth, legal mistake, and precedent.

ABSTRACT In Barker and Dowe, Stephen Barker and Phil Dowe present a range of arguments which they take to demonstrate the paradoxical nature of endurantism. I claim that the endurantist has convincing replies to each argument.

A study of the major themes in traditional and contemporary philosophy.

Many thanks to Robert Neville for commenting on my article. Because the comments were brief and largely ampliative, my response will also be brief and take off from his points.First, a clarification. Professor Neville says that "the point is not to bring in more Chinese philosophers." This is stated correctly in the sense that my main point is not about identity diversity, but the statement could be misconstrued as an opposition on my part to increasing identity diversity in philosophy programs. (...) I want to prevent such a misconstrual by stating plainly that I think the demographic makeup of American philosophy departments should more or less reflect the... (shrink)

L’un des paradoxes de l’observation sociale et de la biographie est de voir à quel point les individus les plus originaux manifestent en temps de crise des réactions identiques à celles des moins cultivés et des plus conventionnels. En août 1914, Wittgenstein s’engagea sous les drapeaux, partageant l’enthousiasme et la dévotion qui s’étendait sur l’Autriche tout comme sur l’Allemagne..