On examining the identity, reason and mission of the European Union this book contributes to eliminating the ideological deficit, which is still argued and ...

Este ensayo explora el papel crucial de la experiencia en la interpretación arqueológica y su relevancia en la investigación científica del pasado. Destaco el análisis detallado de esta noción, a menudo pasada por alto en las discusiones filosóficas sobre el conocimiento arqueológico. La tesis principal sostiene que la experiencia, concebida como una acción que progresa a través de etapas de actos constitutivos controlados, desempeña un papel fundamental. El argumento central distingue la experiencia según la lógica de la investigación empírica de (...) Dewey de las perspectivas pragmáticas en arqueología. Subrayo la necesidad de considerar la investigación arqueológica como una actividad dinámica y controlada en constante crecimiento. Expongo argumentos basados en el pensamiento de Dewey, destacando la importancia de regresar al pragmatismo clásico para obtener una comprensión más profunda del papel de la experiencia en la investigación arqueológica y su contribución al entendimiento del pasado. (shrink)

El autor describe y comenta la obra literaria de Abraham Maimónides que ilustra con la traducción de dos escritos de Abraham, uno donde el hijo de Maimónides describe sus afanes literarios y otro donde defiende a su padre contra los ataques de los tradicionalistas. Importante es también el testimonio del historiógrafo Yosef Sambari sobre el hijo de Maimónides. En conjunto la obra de Abraham tiene una tendencia racionalista, heredada de su padre, pero con un sesgo de pietismo, que heredó de (...) la familia materna, y que se inspira en las corrientes sufistas islámicas. (shrink)

A ubiquitous feature of active sleep in mammals and birds is its relative abundance in early development. In rat pups across the first two postnatal weeks, active sleep promotes the expression of synchronized oscillatory activity within and between cortical and subcortical sensorimotor structures. Sensory feedback from self-generated myoclonic twitches – which are produced exclusively during active sleep – also triggers neural oscillations in those structures. We have proposed that one of the functions of active sleep in early infancy is to (...) provide a context for synchronizing developing structures. Specifically, neural oscillations contribute to a variety of neurodevelopmental processes, including synapse formation, neuronal differentiation and migration, apoptosis, and the refinement of topographic maps. In addition, synchronized oscillations promote functional connectivity between distant brain areas. Consequently, any condition or manipulation that restricts active sleep can, in turn, deprive the infant animal of substantial sensory experience, resulting in atypical developmental trajectories. The synchronization of rhythmic neural activity across brain structures provides evidence of communication. In developing sensorimotor networks, such oscillations are triggered most clearly and prominently during REM sleep. We propose that REM sleep provides a context for the emergence and expression of functional connectivity in the developing sensorimotor system. (shrink)

El presente artículo recapacita sobre las reformas normativas acontecidas en las últimas décadas respecto al uso racional de los medicamentos, y las medidas operadas en torno a la disminución del gasto farmacéutico. En este contexto, debe destacarse el elevado coste de las terapias biológicas y las dificultades de acceso a las mismas —especialmente en los países en vías de desarrollo—. Los medicamentos biosimilares son poseedores de garantías sanitarias análogas —semejantes o equivalentes— a los medicamentos de referencia, pero no están sometidos (...) a una protección por una patente y facilitan la accesibilidad a los pacientes, así como al reparto equitativo de los recursos terapéuticos. Además, algunos de ellos están incluido en la lista de medicamentos esenciales de la Organización Mundial de la Salud (OMS).Asimismo, se examina el papel de los medicamentos biosimilares como esenciales y la posibilidad de mejorar el acceso equitativo a estos recursos sanitarios a través de la prestación farmacéutica. (shrink)

The complex world of thought and sensitivity in the sphere of contemporary art has entailed the revision and exclusion of disciplines aimed at providing a model to explain and conceptualize reality. Art history, as one such discipline, has had many of its contributions questioned from Gombrich’s epistemological reformulation to the postmodern discourses, which extol the death of the author, the post-structuralist idea of tradition as a textual phenomenon, and the declaration of the death of history as a consequence of the (...) hybridization of disciplines and of other bran- ches of human knowledge. Nevertheless, it can be demonstrated that proposals as those by Julius von Schlosser and Giulio Carlo Argan enclose reflections and methodological aspects which can help us face the task of understanding and visualizing the mediating role of historians in the culture of sensitivity, and the art modulations that have resulted from the blows of history and that, in turn, have shaped both art and art history into what they are or can be to us today. (shrink)

El sujeto es un sistema de producción, reconstrucción, deconstrucción y almacenamiento de yoes con miras a la concreta actuación en un contexto determinado. Hay yoes imaginados (prolépticos), anticipados, proyectos de yoes actualizados y yocs fantaseados (y soñados). Los yoes se constituyen en módulos que el sujeto, como sistema, reutiliza en ulteriores contextos. El sujeto controla la actuación del yo creado para la situación, y lo modifica si su actuación no es del tipo adecuado para el logro del propósito del sujeto. (...) El lugar del sujeto es el neocortex prefrontal; el del yo, el cuerpo y lo que el sujeto le exige hacer para la interacción real o virtual. (shrink)

Honor has been an indispensable reference in the life of individuals and societies throughout the course of human history. As a basic concern of men and women, the phenomenon already appears in the earliest literary testimonies. The heroes of the Greek, Roman or German epic poems adapt their behavior to the demands of this particular deity, honor. Literature, at any time, in any culture, in any language, makes constant use of honor as an effective dramatic element. The recurrent presence is (...) certainly a reflection of the actual significance the phenomenon of honor had in everyone’s life. This essay clarifies why honor is given such importance; why it has been considered to be more valuable for the individual than his/her own life. To this end, the mention of public opinion is unavoidable. This phenomenon, in its social psychological conception, is the key that permits us to enlighten the labyrinth of honor. (shrink)

MASMELA. Carlos. Hegel: la desgraciada reconciliación del espíritu. Madrid: Editorial Trotta, 2001, 185 p.

In daily academic life, students are exposed to a wide range of potentially stressful situations which could negatively affect their academic achievement and their health. Among the factors that could be weakened by academic stress, attention has been paid to expectations of self-efficacy, which are considered one of the most important determinants for student engagement, persistence, and academic success. From a proactive perspective, research on academic stress has emphasized the importance of coping strategies in preventing harmful consequences. In recent years, (...) there has been a growing interest in discovering the extent to which individuals are able to combine different coping strategies and the adaptive consequences this flexibility entails. However, studies using this person-centered approach are still scarce in the academic context. On that basis, this current study had two objectives: (a) to examine the existence of different profiles of university students based on how they combined different approach coping strategies (positive reappraisal, support seeking, and planning); and (b) to determine the existence of differences in general expectations of self-efficacy between those coping profiles. 1072 university students participated in the study. The coping profiles were determined by Latent Profile Analysis (LPA). The differences in the self-efficacy variable were determined using ANCOVA, with gender, university year, and degree type as covariates. Four approach coping profiles were identified: (a) low generalized use of approach coping strategies; (b) predominance of social approach coping approaches; (c) predominance of cognitive approach coping approaches; (d) high generalized use of approach coping strategies. The profile that showed that a greater combination of the three strategies was related to higher general self-efficacy expectations, and vice versa. These results suggest that encouraging flexibility in coping strategies would help to improve university students’ self-efficacy. (shrink)

Educational interventions are necessary to develop mathematical competence at early ages and prevent widespread mathematics learning failure in the education system as indicated by the results of European reports. Numerous studies agree that domain-specific predictors related to mathematics are symbolic and non-symbolic magnitude comparison, as well as, number line estimation. The goal of this study was to design 4 digital learning app games to train specific cognitive bases of mathematical learning in order to create resources and promote the use of (...) these technologies in the educational community and to promote effective scientific transfer and increase the research visibility. This study involved 193 preschoolers aged 57–79 months. A quasi-experimental design was carried out with 3 groups created after scores were obtained in a standardised mathematical competence assessment test, i.e., low-performance group, high-performance group, and control group. The results show that training with the 4 digital learning app games focusing on magnitude, subitizing, number facts, and estimation tasks improved the numerical skills of the experimental groups, compared to the control group. The implications of the study were, on the one hand, provided verified technological tools for teaching early mathematical competence. On the other hand, this study supports other studies on the importance of cognitive precursors in mathematics performance. (shrink)

Se realiza la investigación con el objetivo de perfeccionar la obtención del consentimiento informado en las amputaciones mayores de causa vascular en el Servicio de Angiología del Hospital Universitario Manuel Ascunce Domenech. Se constató debilidades en la institucionalización del consentimiento informado y específicamente en el caso de tales amputaciones. Se utilizaron métodos y técnicas del nivel empírico: encuestas a 30 pacientes con riesgo inminente de amputación. El 64% eran mayores de 65 años, 73 % femeninos, todos escolarizados y 73% residentes (...) urbanos. Los resultados más relevantes fueron: que el 54% de los pacientes manifestaron debe existir consentimiento en la aceptación de la amputación, aunque un grupo no despreciable el 37% declinó este derecho a favor de sus familiares. A los médicos se les realizó una entrevista y aunque no hubo unanimidad de criterios, todos coincidieron en que debía legislarse este consentimiento, como parte del perfeccionamiento de los servicios de salud. Research is conducted to improve the process of obtaining informed consent for major amputations due to vascular causes in the Angiology Service of the Manuel Ascunce Domenech Teaching Hospital. Deficiencies were identified in the institutionalization of informed consent protocols, most specifically as they relate to major lower limb amputations. Empirical methods and techniques were used. Thirty patients at imminent risk of amputation were surveyed by questionnaire methods; 64% of those surveyed were of 65 years of age, 73% were female, all of them had an average educational level, and 73% were urban residents. The results indicated that 54% of patients recognized the importance of informed consent in cases of amputation, although a rather considerable group declined this right for their families. Physicians were also interviewed and, although there was no unanimity of criteria, all of them considered that this consent should be legislated as part of the improvement of health services. (shrink)

El presente trabajo tiene la finalidad de presentar una propuesta teórico-metodológica que profundiza los estudios acerca de la representación de los indígenas en los diversos relatos/discursos producidos por la prensa en América, desde la colonia hasta nuestros tiempos. Para cumplir con lo enunciado, se procederá a 1) presentar, por una parte, algunos antecedentes teóricos respecto a nociones como relación de sucesos, representaciones, prensa, discurso y poder; 2) se entregarán algunas referencias acerca de los avances de investigaciones centradas en el tema (...) de lo mapuche; y, finalmente, 3) se describirá una propuesta metodológica focalizada en un modelo de análisis del discurso que permita desarrollar de forma pertinente el estudio de la representación discursiva de la otredad/indígena en la prensa hispanoamericana. (shrink)

Ernst Bloch formulated problems of enormous philosophical and human relevance. He held that in our contemporary situation we have but two questions concerning the fundamental direction of our lives and history: we must choose, first, between hopeless nihilism and transcendent hope; and, second, between transcendent hope with transcendence and transcendent hope without transcendence. Bloch opted for the transcendent hope without transcendence and formulated a hard critique of hope with transcendence. Josef Pieper and Bernard Schumacher have offered a competent response to (...) Bloch from the Catholic perspective. However, we offer here a little explored aspect of the problem by demonstrating that Bloch’s metaphysical arguments do not consider that (a) a material reality necessarily has the concrete potentiality of dissolving, and (b) therefore, left to itself, it will dissolve necessarily in infinite time; and that (c) no effect can have a reality disproportionate to its cause, which is the reason why (d) no immortal reality can proceed from mortal reality without the intervention of a higher cause. (shrink)

Bernardi Perini, G. Aceto italico e poesia luciliana: Hor. Sat. I 7.--Bernardinello, S. Bessarione riassume la Fisica di Aristotele.--Bottecchia, M. E. I Mechanicha di Aristotele nel Parisinus graecus 2507.--Bottin, L. La tradizione araba della Retorica di Aristotele e il problema dell'exemplar decurtatum.--Chiereghin, F. Analogie di struttura tra la metodologia della storiografia filosofica di Platone e di Kant.--Ciani, M. G. Poesia come enigma.--Degani, E. Hippon. fr. 40 Med.--Donaldi, F. Note preparatorie all'edizione dell'Encomio di Elena gorgiano nella traduzione latina inedita di Pietro (...) Bembo.--Fumarola, V. Euripide e la tetralogia della femminilità.--Gentilini, A. Una consolatoria inedita del Bessarione.--Ghinatti, F. I culti greci di Paestum.--Longo, O. Note all'Elena e alle Nuvole.--Lunelli, A. Solis rota.--Meschini, A. Su alcuni luoghi del Reso.--Mignucci, M. In margine al concetto aristotelico di esistenza.--Mioni, E. L'Antologia greca da Massimo Planude a Marco Musuro.--Pianezzola, E. Haurio=ferio, perfodio. Un calco omerico mediato dagli scolii.--Pontani, F. M. La distruzione di Melos di Ghiannis Ritsos.--Rinaldi Mioni, G. Aspetto verbale nel greco classico e strutturalismo.--Riondato, E. Problematicità semantica ed etica nell'Etica a Nicomaco.--Serra, G. Alcune osservazioni sulle traduzioni dall'arabo in ebraico e in latino del De generatione et corruptione di Aristotele e dello pseudo-aristotelico Liber de causis.--Traina, A. Convexo nutantem pondere mundum (Verg. Ecl. 4,50).--Valentini, R. La reintroduzione dell'onciale e la datazione dei manoscritti greci in minuscola. (shrink)

RésuméGian-Carlo Rota est l’un des rares grands mathématiciens de la deuxième moitié du XX e siècle dont l’intérêt pour la logique formelle soit aussi ouvertement déclaré et ne se soit jamais démenti, depuis sa formation d’étudiant à Princeton jusqu’à ses derniers écrits. Plus exceptionnel encore, il fait partie des rares lecteurs assidus de Husserl à s’être aperçu que la phé-noménologie poursuivait un projet de réforme de la logique formelle. L’article propose d’attester l’existence d’un tel projet chez Husserl ; d’en examiner (...) la réappropriation et les prolongements chez Rota.Gian-Carlo Rota is among the few great mathematicians of the second-half of the XXth century whose interest in formal logic is openly declared and has never flagged, since his training as a student in Princeton up to his last writings. Even more exceptional, he belongs to the rare diligent readers of Husserl, who noticed that phenomenology was pursuing a project of reform of formal logic. This paper propose to testify to the existence of such a project in Husserl; to examine how it is taken over and continued by Rota. Gian-Carlo Rota è uno dei pochi grandi matematici della seconda metà del ventesimo secolo, il cui interesse per la logica formale è, dalla sua formazione come studente a Princeton al suo ultimi scritti, apertamente dichiarato e mai negato. Cosa ancora più eccezionale, Rota è uno dei rari lettori assidui di Husserl ad aver percepito che la fenomenologia stava perseguendo un progetto di riforma della logica formale. L’articolo propone di attestare l’esistenza di un tale progetto in Husserl e di esaminare la sua riappropriazione e le sue estensioni proposte da Gian-Carlo Rota.This article is in French. (shrink)

Este estudio muestra la notable herencia del Barroco que retoma la cultura psicoanalítica. El punto de partida es la constatación de la permanencia de ciertos núcleos barrocos en el psicoanálisis, tanto en lo que refiere a sus discursos identitarios y a sus programas de representación, como en sus considerandos teóricos y prácticos. Esta vinculación de la cultura barroca con la psicoanalítica la exploramos a través de los siguientes descriptores: señas de identidad, arte de la mirada, concepción terapéutica y estilo. Por (...) último se pretende promover una reflexión sobre lo barroco como herencia relevante para tener una visión más profunda y comprensiva de la cultura psicoanalítica y, por extensión, de nuestra actualidad sociocultural. (shrink)

Rho proteins belong to the small GTPases superfamily. They function as molecular switches that, in response to diverse stimuli, control key signaling and structural aspects of the cell. Although early studies proposed a role for Rho GTPases in cellular transformation, this effect was underestimated due to the fact that no genetic mutations affecting Rho‐encoding genes were found in tumors. Recently, it has become evident that Rho GTPases participate in the carcinogenic process by either overexpression of some of the members of (...) the family with oncogenic activity, downmodulation of other members with suggested tumor suppressor activity, or by alteration of upstream modulators or downstream effectors. Thus, alteration of the levels of expression of different members of the family of Rho GTPases has been detected in many types of human tumors leading to a great interest in the cellular effects elicited by these oncoproteins. This essay reviews the current evidence of dysregulation of Rho signaling by overexpression in human tumors. BioEssays 27:602–613, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

Resumen Este artículo analiza, en discusión con Joaquín García-Huidobro y Alejandro Miranda, la conveniencia de utilizar en moral sexual el argumento de la facultad pervertida, conforme al cual sería inmoral frustrar el fin natural de las facultades reproductivas. Según García-Huidobro y Miranda este argumento sólo puede utilizarse desde el “principio de totalidad”, pues su uso aislado llevaría a los absurdos denunciados por la New Natural Law Theory. Con vistas a una reconsideración de este argumento, se demuestra la importancia de considerar (...) la ética en su carácter tópico o contextual. Así, es en el ámbito de la templanza y de las inclinaciones sexuales donde el AFP cobra un papel normativo; en cambio, el “principio de totalidad” entra en juego cuando se está considerando el problema del límite de las intervenciones médicas.This paper focuses on the adequacy of using the so-called perverted faculty argument within the context of sexual morality. According to this argument, frustrating the reproductive faculty would be immoral. Professors García-Huidobro and Miranda think that this argument can be appropriately used only within the framework of the principle of totality. They argue that an unqualified use of the PFA would lead to the absurdities pointed out by the New Natural Law Theory. In order to see the PFA in a new light we demonstrate the importance of respecting the dialectical or contextual nature of Ethics. Thus, regarding temperance, and especially sexual inclinations, the PFA has a clear normative role. The principle of totality, instead, must be used when considering the problem of the moral limits of medical interventions. (shrink)

La economía ortodoxa oculta la cualidad esencial del dinero en tanto institución social de orden intelectual. En su lugar, lo presenta como una mercancía con el fin de ajustar de este modo su teoría del dinero al contexto teórico general del mercado como una esfera independiente del campo social que se autorregula virtuosamente por sí mismo, de manera natural, sin ninguna intervención externa. Sostengo que este sesgo naturalista tiene, no obstante, unos fundamentos que van más allá de una mera posición (...) teórica dentro de los debates de la ciencia económica. Su trasfondo último está implícito en la propia ontología moderna de raíces nominalistas y calvinistas, que subyace al pensamiento liberal, y que juzga que las pretensiones de la razón humana acerca de un conocimiento cualitativo —fundado pues en la potencia noética de la imaginación— sobre el bien del hombre y la sociedad son intrínsecamente ilegítimas. (shrink)

All the acts of behaviour are judgements of reality (held by subject on the object). The first stage in th:is judgesment is denotative (judgement of facts). The second is connotative (judgement of value). Denotative judgement contains 6 components: diacriticity, organization, identification, naming, specialization, timing. All of them have to be provided with values of truth. Value of truth of denotative judgements derives from their value of truth in context. Context is a consensus space. Thus, subject denotes object starting from theory (...) of context he holds. As far as psycho(patho)logy is corcerned, starting from a theory of perception -instead of a theory of denotation- has been a decisive setback. (shrink)

Counselling y cuidados paliativos es el título del libro que conjuntamente decidieron escribir la doctora Esperanza Santos y el profesor José Carlos Bermejo. En esta obra de fácil lectura y con consejos muy prácticos y útiles, se presentan elementos fundamentales para brindar un acompañamiento de óptima calidad en el cuidado paliativo, así como la posibilidad de hacer un autoexamen de cómo los cuidadores de los pacientes vienen prestando sus servicios e incluso para no caer en burnout. Este libro es (...) de gran utilidad, tanto para los profesionales de la salud que trabajan en las unidades de cuidados paliativos, como para personas que dedican gran parte de su tiempo al cuidado de familiares con enfermedades terminales o que pasan por procesos prolongados de enfermedad. Con ejemplos de conversaciones de la vida real entre cuidadores y pacientes, la lectura del libro se hace, a la vez, agradable, divertida y profundamente reflexiva. Para citar esta reseña / To cite this review / Para citar esta resenha Rosas-Jiménez CA. Esperanza Santos y José Carlos Bermejo. Counselling y cuidados paliativos. Bilbao: Desclée de Brouwer-Centro de Humanización de la Salud, 2015, 164 pp. ISBN: 978-84-330-2786-3. Pers Bioet. 2019; 23: 137-139. DOI: https://doi.org/10.5294/pebi.2019.23.1.9. (shrink)