The Drosophila compound eye is an excellent experimental system for analysing fate induction of identifiable single cells. Each ommatidium, a unit eye, contains eight photoreceptors (R1‐R8), and the differentiation of these photoreceptors occurs in the larval eye imaginal disc in discrete steps: first R8 is determined, then R2/R5, R3/R4, R1/R6 and finally R7. Induction of R7, in particular, has been extensively studied at the molecular level. The R8 photoreceptor presents on its surface a ligand, Bride of Sevenless, that binds and (...) activates Sevenless receptor tyrosine kinase in the R7 precursor. Autophosphorylated Sevenless initiates a Ras1‐mediated cascade, which eventually activates transcription factors in the nucleus via Raf1 and MAP kinases, resulting in R7 development. However, recent studies indicate that Sevenless (Sev) functions just to neuralize the cell and has no role in R7 fate determination per se. It appears that the R7 fate may represent the lowest rung of a ‘neuronal ground state’, which is attained without any specific inductive cue. It is plausible that the R7 precursor is actively prevented from taking on the neuronal fate and this inhibition is removed by activation of Sev. (shrink)

Motor learning is the process of updating motor commands in response to a trajectory error induced by a perturbation to the body or vision. The brain has a great capability to accelerate learning by increasing the sensitivity of the memory update to the perceived trajectory errors. Conventional theory suggests that the statistics of perturbations or the statistics of the experienced errors induced by the external perturbations determine the learning speeds. However, the potential effect of another type of error perception, a (...) self-generated error as a result of motor command updates, on the learning speeds has not been examined yet. In this study, we dissociated the two kinds of errors by controlling the perception of the aftereffect using a channel-force environment. One group experienced errors due to the aftereffect of the learning process, while the other did not. We found that the participants who perceived the aftereffect of the memory updates exhibited a significant decrease in error-sensitivity, whereas the participants who did not perceive the aftereffect did not show an increase or decrease in error-sensitivity. This suggests that the perception of the aftereffect of learning attenuated updating the motor commands from the perceived errors. Thus, both self-generated and externally induced errors may modulate learning speeds. (shrink)

Death in the life of the samurai -- An introduction to Yamamoto Tunetomo's Hagakure -- The Hagakure -- A leisurely chat in the evening shadows -- A samurai must devote his heart firmly to bushidō -- Hardship is a beneficial experience -- There is nothing as deep as giri -- Close your eyes and think of your lord -- Death is a punishment not meted out lightly -- Even if it contains poison, what's the big deal? -- Naritomi Hyōgo's (...) words about achieving victory -- The quarrel (kenka) of Araki Kuzaemon -- You are weaker than you look -- "Victory or defeat is a trivial matter" -- Military strategies. (shrink)

Some of the basic substructural logics are shown by Ono to have the disjunction property (DP) by using cut elimination of sequent calculi for these logics. On the other hand, this syntactic method works only for a limited number of substructural logics. Here we show that Maksimova's criterion on the DP of superintuitionistic logics can be naturally extended to one on the DP of substructural logics over FL. By using this, we show the DP for some of the substructural logics (...) for which syntactic methods don't work well. (shrink)

Besides sensory characteristics of food, food-evoked emotion is a crucial factor in predicting consumer’s food preference and therefore in developing new products. Many measures have been developed to assess food-evoked emotions. The aim of this literature review is (i) to give an exhaustive overview of measures used in current research and (ii) to categorize these methods along measurement level (physiological, behavioral, and cognitive) and emotional processing level (unconscious sensory, perceptual / early cognitive, and conscious / decision making) level. This 3x3 (...) categorization may help researchers to compile a set of complementary measures (‘toolbox’) for their studies. We included 101 peer-reviewed articles that evaluate consumer’s emotions and were published between 1997 to 2016, providing us with 59 different measures. More than 60% of these measures are based on self-reported, subjective ratings and questionnaires (cognitive measurement level) and assess the conscious / decision-making level of emotional processing. This multitude of measures and their overrepresentation in a single category hinders the comparison of results across studies and building a complete multi-faceted picture of food-evoked emotions. We recommend (1) to use widely applied, validated measures only, (2) to refrain from using (highly correlated) measures from the same category but use measures from different categories instead, preferably covering all three emotional processing levels, and (3) to acquire and share simultaneously collected physiological, behavioral, and cognitive datasets to improve the predictive power of food choice and other models. (shrink)

Firstly I characterize Simple Partial Logic (SPL) as the generalization and extension of a certain two-valued logic. Based on the characterization I present two definitions of validity in SPL. Finally I show that given my characterization these two definitions are more appropriate than other definitions that have been prevalent, since both have some desirable semantic properties that the others lack.

The earliest Chinese record of the maritime relations between India and China can be found in the “History of the Former Han Dynasty” (Chien Han-shu) which covers the period from B.C. 206 to A.D. 23. In its chapter (28b) on geography it is stated that ever since the time of the Emperor Wu (Wu Ti, B.C. 14087) the country called Huang-chih has sent tribute to the Chinese court, which in turn dispatched envoys to this remote country. Huang-chih has been identified (...) by many scholars with Kāñcī (Conjeeveram) on the east coast of South India. It is recorded that there were chief interpreters belonging to the Yellow Gate (the office of eunuchs serving in the palace) who went to sea to buy bright pearls, opaque glasses and other rare articles, taking with them from China gold and various kinds of silk for exchange. (shrink)

This paper considers methodological issues of awareness during adult second language acquisition. Specifically, the paper deals with the issue of instructional orientations, the issue of biases in knowledge measurement, and the issue of reactivity in the online think-aloud protocol. Detailed reviews of prominent SLA research that has investigated the possibility of implicit SLA reveal that the instruction on implicit learning does not guarantee that learners engage in the implicit learning mode, that the majority of SLA research has employed only tests (...) of “explicit learning” such as untimed grammaticality judgment, and that there is some evidence that the online think-aloud protocol causes negative reactivity particularly when it is metalinguistic in nature. (shrink)

La présente étude examine comment les intellectuels japonais tentèrent d’introduire l’utilitarisme lors du premier stade d’un processus de modernisation dans la seconde moitié du XIXe siècle. Elle décrit les efforts significatifs qu’ils consacrèrent à la traduction des œuvres ou des textes de Bentham et de Mill en créant de nombreux mots japonais nouveaux. Car, jusqu’à la fin de la société agraire quasi féodale du shogunat Tokugawa, il n’y avait quasiment pas eu de concepts équivalents pour des notions telles que l’individu, (...) la liberté, le droit, la démocratie, par exemple. La Restauration de Meiji de 1868, au premier abord, suggère par son nom une restauration de l’ancien régime ; mais en réalité c’était l’inverse, car il s’agissait d’un tournant décisif pour le Japon, dont le but était d’établir une nouvelle société industrielle moderne. La présente recherche fournit tout d’abord une liste chronologique des traductions des œuvres de Bentham et Mill réalisées au cours des deux premières décennies après la Restauration. Ensuite, elle évalue la précision et la validité du résultat de la traduction, en prenant comme exemple le premier paragraphe de l’Introduction aux Principes de la Morale et de la Législation. En troisième lieu, elle examine dans quelle mesure les intellectuels japonais de cette époque comprirent l’utilitarisme dans le processus de création des nouvelles traductions en japonais. Ce processus était issu de la tradition consistant à créer différents concepts japonais uniques, sous forme de mots composés de caractères hiéroglyphiques chinois, ancrés profondément dans l’influence culturelle du confucianisme qui domina longtemps à partir du VIe siècle. Enfin, la présente étude évalue comment les premières présentations de Bentham et Mill influencèrent la génération suivante d’intellectuels japonais. Ce résultat peut expliquer dans une certaine mesure pourquoi le Japon ne compte démographiquement que 0,8 % de chrétiens, et pourquoi la société japonaise est fondamentalement laïque et tournée vers le succès économique. (shrink)

現代の物質像の根本的変容に対し、アリストテレス以来の実体主義を洗練、実在の本性に迫る包括的形而上学理論の構築。.

In my paper 'Validity in Simple Partial Logic'(2002) I made comparison between several definitions of validity in Simple Partial Logic(SPL) and adopted two of them as most appropriate. In this paper, after elaborating more on these two definitions than in my previous paper and considering the characteristics of Partial Semantics, in which these definitions are given, I construct a tableau proof system and prove its soundness and completeness. Then, based on the characterization of Partial Semantics, I will show that we (...) can regard SPL as a logic of extensional alethic modality. (shrink)

西周の私塾での講義「百学連環」の講義録を現代の言葉に置き換え精読することで、文化の大転換期に学術全体をどう見ていたかに迫る。.

For a large natural class of forcing notions, we prove general equivalence theorems between forcing absoluteness statements, regularity properties, and transcendence properties over and the core model . We use our results to answer open questions from set theory of the reals.

Firstly I define a hole as a dependent matter-less endurant, which is a little modification of Casati and Varzi’s definition. Adopting this definition, holes seem to invite three problems about causation: (1)causal closure, (2)ungrounded disposition and (3)causal overdetermination. I will defend my definition against all these problems by showing that holes are limiting cases of physical endurants rather than their opposition and that they have causal powers in a broad sense.

In this paper I give consideration to some apparent impossibilities for the time travelers to the past. After criticizing the views of D. Lewis and K. Vihvelin, I will show in what sense they are really impossible.

Vivre et mourir sans se départir de son courage et perdre son honneur est au coeur du Hagakure, une série de textes écrits par un samouraï du XVIIIe siècle, Yamamoto Tsunetomo. Ce livre est une fenêtre ouverte sur l'esprit du samouraï, éclairant le concept de bushido (la Voie du guerrier), qui précise la manière dont les samouraïs devaient se comporter, se discipliner, vivre et mourir. Alors que pendant de nombreuses années, le Hagakure demeura un texte secret, connu uniquement des (...) samouraïs au service du clan Nabeshima auquel appartenait l'auteur, il fut plus tard reconnu comme un grand classique de la pensée du samouraï. A l'origine, le Hagakure était composé de plus de 1300 textes courts que Tsunetomo dicta à un jeune samouraï sur une période de sept années. William Scott Wilson a sélectionné et traduit ici 300 des textes les plus représentatifs pour créer un ouvrage plus accessible, un guide du samouraï. Aucun autre traducteur n'a su rendre ce texte avec autant de profondeur et d'érudition. Wilson éclaire le Hagakure sous un jour différent : Tsunetomo fait référence au bushido comme à " la voie de la mort, " une description qui a engendré une fascination morbide chez ses lecteurs, particulièrement pendant la Seconde Guerre mondiale. Mais à l'époque de Tsunetomo, le bushido relevait d'un concept plus nuancé qui était étroitement lié au concept zen de muga, la " mort de l'ego ". L'introduction de Wilson fournit l'arrière-plan historique et philosophique pour une lecture plus métaphorique du Hagakure. (shrink)

There are two types of theories regarding many worlds: one is modal, while the other is temporal. The former regards reality as consisting of many possible worlds, while the latter holds that reality consists of many momentary worlds, which are usually called moments. I compare these two theories, paying close attention to the concept of transworld identity and compare trans-possible world identity with trans-momentary world identity (or transmoment identity). I characterize time from the point of many-worlds view, believing this to (...) be one of the best ways of grasping the reality of time. First, I show that there is reason to adopt the many-worlds view because transworld identity is meaningful for both of them, while it is not for space. Second, I argue that transmoment identity is different from transpossible world identity concerning reality. The former is a realistic relation, while the latter is not. Thus, I find that the reality of time is in the relation of transmoment identity. Such a view, I contend, has merit on the basis that it recognizes the reality of time in a sense that is not true of space. (shrink)

In recent years several books by major figures in Japan's modern philosophical tradition have appeared in English, exciting readers by their explorations of the borderlands between philosophy and religion. What has been wanting, however, is a book in a Western language to elucidate the life and thought of Nishida Kitaro, Japan's first philosopher of world stature and the originator of what has come to be called the Kyoto School. No one is more qualified to write such a book than Nishitani (...) Keiji, whose lifetime coincides with the rise and flowering of the Kyoto School and whose own critical contribution to Japanese thought has been so important. _Nishida Kitaro_ is a translation of essays Nishitani wrote about his teacher from 1936 to 1968 and published as a book in 1985. This series of meditations by one master on another provides a remarkable, living portrait of Nishida the person and conveys the enthusiasm he aroused in his students. Examining Nishida's most important work, _An Inquiry into the Good_, Nishitani penetrates to the core of his thought and presents it in language that is a marvel of clarity. (shrink)

Homologous chromosome pairing is required for proper chromosome segregation and recombination during meiosis. The mechanism by which a pair of homologous chromosomes contact each other to establish pairing is not fully understood. When pairing occurs during meiotic prophase in the fission yeast, Schizosaccharomyces pombe, the nucleus oscillates between the cell poles and telomeres remain clustered at the leading edge of the moving nucleus. These meiosis‐specific activities produce movements of telomere‐bundled chromosomes. Several lines of evidence suggest that these movements facilitate homologous (...) chromosome pairing by aligning homologous chromosomes and promoting contact between homologous regions. Since telomere clustering and nuclear or chromosome movements in meiotic prophase have been observed in a wide range of eukaryotic organisms, it is suggested that telomere‐mediated chromosome movements are general activities that facilitate homologous chromosome pairing. BioEssays 23:526–533, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

These volumes present the text of Abū Ma’͑šar’s _Great Introduction to Astrology_ in Arabic and Greek and the divergences in the Latin translations. It provides a fully-comprehensive account of traditional astrological doctrine and its philosophical bases.

The definitive translation of the seminal treatise on the code of the samurai. Living and dying with bravery and honor is at the heart of Hagakure, a series of over 1,300 short texts written by eighteenth-century samurai Yamamoto Tsunetomo. These texts illuminate the classic Japanese concept of bushido (the Way of the Warrior), which dictated how samurai were expected to behave, conduct themselves, live, and die. Acclaimed translator William Scott Wilson has selected and translated here three hundred of those (...) texts to create an accessible distillation of this guide, making it one of the most thorough and astonishing windows into the captivating world of the samurai available. This edition includes an introduction that delves into the Zen concept of muga, or “death” of the ego, giving an in-depth historical and philosophical background for the more metaphorical reading of Hagakure that is based on Tsunetomo’s reference to bushido as “the Way of death.” Through this lens, which has held a morbid fascination for readers through the years, the classic takes on a fresh and nuanced appeal. This book was previously published under the title Hagakure. This book is part of the Shambhala Pocket Library series. The Shambhala Pocket Library is a collection of short, portable teachings from notable figures across religious traditions and classic texts. The covers in this series are rendered by Colorado artist Robert Spellman. The books in this collection distill the wisdom and heart of the work Shambhala Publications has published over 50 years into a compact format that is collectible, reader-friendly, and applicable to everyday life. (shrink)

Recently, Bourne constructed a system of three-valued logic that he supposed to replace Łukasiewicz’s three-valued logic in view of the problems of future contingents. In this paper, I will show first that Bourne’s system makes no improvement to Łukasiewicz’s system. However, finding some good motivations and lessons in his attempt, next I will suggest a better way of achieving his original goal in some sense. The crucial part of my way lies in reconsidering the significance of the intermediate truth-value so (...) as to reconstruct Łukasiewicz’s three-valued logic as a kind of extensional modal logic based on partial logic. (shrink)

This study examines the process by which the concept of quality of life has been increasing in importance as the key to ASEAN's socio-cultural integration. This study also focuses on the current trend that emphasizes subjective quality of life and clarifies that ASEAN has been moving toward including this perspective. Then, it analyzes the subjective quality of life of people in ASEAN in terms of self-assessment and the multidimensional World Health Organization Quality of Life metric by using data from the (...) ASEAN Barometer 2009. (shrink)

The involvement of nitric oxide in cerebellar long-term depression is supported by the observation that nitric oxide is released by climbing fiber stimulation and by pharmacological tool usage. Two forms of long-term depression should be distinguished by their physiological relevance. [CRÉPEL et al.; LINDEN; VINCENT].

As a criterion of a good firm, a lucrative and growing business has been said to be important. Recently, however, high profitability and high growth potential are insufficient for the criteria, because social influences exerted by recent firms have been extremely significant. In this paper, high social relationship is added to the list of the criteria. Empirical corporate social performance versus corporate financial performance (CSP–CFP) relationship studies that consider social relationship are very limited in Japan, and there are no definite (...) conclusions for the studies in the world, because of scant data and the inappropriate methods, especially for supporting linear hypothesis which these studies are based on. In this paper, the CSP–CFP relationship is analyzed by an artificial neural networks model, which can deal with a non-linear relationship, using 10-year follow-up survey data. (shrink)

近代仏教の確立者と称される清沢満之の思想を解明するだけでなく、その思想が夏目漱石、正岡子規などをはじめとする同時代の人々や、後世の社会に与えた影響にも着目することで、今後の清沢研究にまったく新しい視座 を提供する刺激的な入門書!