There is increasing evidence for the wide‐spread existence of functionally redundant genetic pathways in developmental processes. However, both their significance and manner of evolution are still matters of debate. I will argue here that redundancy of gene actions may, in fact, be a necessary requirement for the development and evolution of complex life forms. One can view development as a process that transmits information from the egg to the adult organism. Transmission of information is, however, always an error‐prone process, which (...) can only be safeguarded by including redundancies in the message. Molecular examples for well analysed redundant processes indicate that redundancies may best be understood within a conceptual framework of overlaps between different gene functions. (shrink)

Ceteris Paribus (cp-)laws may be said to hold only “other things equal,” signaling that their truth is compatible with a range of exceptions. This paper provides a new semantic account for some of the sentences used to state cp-laws. Its core approach is to relate these laws to natural language on the one hand — by arguing that cp-laws are most naturally expressed with generics — and to natural kinds on the other — by arguing that the semantics of generics (...) in the context of the special sciences are best spelled out by appeal to natural kinds. The paper then goes on to draw on these semantics in order to illuminate several problems raised by cp-laws, some familiar, some new. (shrink)

I defend economic and social rights as human rights, and as a feasible approach to addressing world poverty. I propose a modest conception of economic and social rights that includes rights to subsistence, basic health care and basic education. The second part of the paper defends these three rights. I begin by sketching a pluralistic justificatory framework that starts with abstract norms pertaining to life, leading a life, avoiding severely cruel treatment, and avoiding severe unfairness. I argue that economic and (...) social rights are not excessively burdensome on their addressees and that they are feasible worldwide in the appropriate sense. Severe poverty violates economic and social rights, and accordingly generates high-priority duties of many parties to work towards its elimination. (shrink)

Abstract This paper discusses the semantic theory presented in Robert Brandom’s Making It Explicit . I argue that it is best understood as a special version of dynamic semantics, so that these semantics by themselves offer an interesting theoretical alternative to more standard truth-conditional theories. This reorientation also has implications for more foundational issues. I argue that it gives us the resources for a renewed argument for the normativity of meaning. The paper ends by critically assessing the view in both (...) its development and motivations. Content Type Journal Article Pages 1-22 DOI 10.1007/s11098-011-9768-4 Authors Bernhard Nickel, Harvard University, Cambridge, MA, USA Journal Philosophical Studies Online ISSN 1573-0883 Print ISSN 0031-8116. (shrink)

Trust is a kind of risky reliance on another person. Social scientists have offered two basic accounts of trust: predictive expectation accounts and staking (betting) accounts. Predictive expectation accounts identify trust with a judgment that performance is likely. Staking accounts identify trust with a judgment that reliance on the person’s performance is worthwhile. I argue (1) that these two views of trust are different, (2) that the staking account is preferable to the predictive expectation account on grounds of intuitive adequacy (...) and coherence with plausible explanations of action; and (3) that there are counterexamples to both accounts. I then set forward an additional necessary condition on trust, according to which trust implies a moral expectation. The content of the moral expectation is this: W hen A trusts B to do x, A ascribes an obligation to B to do x, and holds B to this obligation. This moral expectation account throws new light on some of the consequences of misplaced trust. I use the example of physicians’ defensive behavior to illustrate this final point. (shrink)

Bernhard Nickel presents a theory of generic sentences and the kind-directed modes of thought they express. The theory closely integrates compositional semantics with metaphysics to solve the problem that generics pose: what do generics mean? Generic sentences are extremely simple, yet if there are patterns to be discerned in terms of which are true and which are false, these patterns are subtle and complex. Ravens are black, and lions have manes: statistical measures cannot do justice to the facts, but (...) what else is there that has a hope of giving us insight into what we are capturing across so many domains? Nickel argues that generics are the top of a fundamentally explanatory iceberg, and that this explanatory framework is deeply intertwined with the semantics of the language we use to express them. In providing an integrated semantic and metaphysical theory of generics, he aims to solve old puzzles and draw attention to new phenomena. (shrink)

Building upon the scholarship of Michael Polanyi, William Poteat has dedicated himself to offering an alternative model to the Cartesian dichotomy of mind and matter that has dominated Western thought for centuries. These essays, collected by James Nickell and James Stines, cover a wide range of subjects, from Poteat's analysis of the epistemological crisis brought on by the Cartesian program to his first attempts at formulating an alternative to the mind-body dichotomy. These essays relentlessly diagnose the present situation of Western (...) thought by making explicit the philosophical presuppositions to which it is committed. They include theological affirmations, reflections on epistemology, conceptual analyses, as well as dialogues with other writers in the field of cultural criticism and linguistic theory such as George Steiner, Noam Chomsky, and Walker Percy. Most significant is Poteat's bold affirmation of the primacy of persons and his analysis and critique of our cultural misconstructions of human awareness. _The Primacy of Persons and the Language of Culture_ provides an excellent introduction to the scholarship of William Poteat. It should be of particular interest to scholars of philosophy and theology, as well as others who share Poteat's deep concern for the state of human culture. ---------------------------------------------------------------------------------------------------- -------------------------------- The above was already on the database - below was copied from the web William Poteat has dedicated himself to offering an alternative model to the Cartesian dichotomy of mind and matter that has dominated Western thought for centuries. These essays further diagnose the present situation of Western thought by making explicit the philosophical presuppositions to which it is committed. (shrink)

I contrast two approaches to the interpretation of generics such as ‘ravens are black:’ majority-based views, on which they are about what is the case most of the time, and inquiry-based views, on which they are about a feature we focus on in inquiry. I argue that majority-based views face far more systematic counterexamples than has previously been supposed. They cannot account for generics about kinds with multiple characteristic properties, such as ‘elephants live in Africa and Asia.’ I then go (...) on to sketch an inquiry-based view. (shrink)

A person presented with adequate but not conclusive evidence for a proposition is in a position voluntarily to acquire a belief in that proposition, or to suspend judgment about it. The availability of doxastic options in such cases grounds a moderate form of doxastic voluntarism not based on practical motives, and therefore distinct from pragmatism. In such cases, belief-acquisition or suspension of judgment meets standard conditions on willing: it can express stable character traits of the agent, it can be responsive (...) to reasons, and it is compatible with a subjective awareness of the available options. (shrink)

Technology is a practically indispensible means for satisfying one’s basic interests in all central areas of human life including nutrition, habitation, health care, entertainment, transportation, and social interaction. It is impossible for any one person, even a well-trained scientist or engineer, to know enough about how technology works in these different areas to make a calculated choice about whether to rely on the vast majority of the technologies she/he in fact relies upon. Yet, there are substantial risks, uncertainties, and unforeseen (...) practical consequences associated with the use of technological artifacts and systems. The salience of technological failure (both catastrophic and mundane), as well as technology’s sometimes unforeseeable influence on our behavior, makes it relevant to wonder whether we are really justified as individuals in our practical reliance on technology. Of course, even if we are not justified, we might nonetheless continue in our technological reliance, since the alternatives might not be attractive or feasible. In this chapter I argue that a conception of trust in technological artifacts and systems is plausible and helps us understand what is at stake philosophically in our reliance on technology. Such an account also helps us understand the relationship between trust and technological risk and the ethical obligations of those who design, manufacture, and deploy technological artifacts. (shrink)

This fully revised and extended edition of James Nickel's classic study explains and defends the conception of human rights found in the Universal Declaration of Human Rights and subsequent human rights treaties. Combining philosophical, legal, and political approaches, Nickel addresses questions about what human rights are, what their content should be, and whether and how they can be justified.

This paper defends the view that trust is a moral attitude, by putting forward the Obligation-Ascription Thesis: If E trusts F to do X, this implies that E ascribes an obligation to F to do X. I explicate the idea of obligation-ascription in terms of requirement and the appropriateness of blame. Then, drawing a distinction between attitude and ground, I argue that this account of the attitude of trust is compatible with the possibility of amoral trust, that is, trust held (...) among amoral persons on the basis of amoral grounds. It is also compatible with trust adopted on purely predictive grounds. Then, defending the thesis against a challenge of motivational inefficacy, I argue that obligation-ascription can motivate people to act even in the absence of definite, mutually-known agreements. I end by explaining, briefly, the advantages of this sort of moral account of trust over a view based on reactive attitudes such as resentment. (shrink)

As a moral philosopher, the perspective I will take in this chapter is one of argumentation and informed judgment about two main questions: whether individuals should ever choose to conduct human embryonic stem cell research, and whether the law should permit this type of research. I will also touch upon a secondary question, that of whether the government ought to pay for this type of research. I will discuss some of the main arguments at stake, and explain how the ethical (...) conflict over these questions differs from the political conflict over them. I will be guided throughout by the assumption that the unique scientific and clinical promise of human embryonic stem cell research is significant. Those who have doubts about this assumption should consult other chapters in this volume in which the issue is addressed directly. I begin with one of the basic facts relevant to the ethical issue of stem cell research: you and I, along with everybody else we know, developed out of clumps of primordial cells, which happen to be the very same clumps that serve as the source for human embryonic stem cells in the laboratory. Let us call these “source cells” for short, since they can be used in this way. Each individual has developed into whatever she is now out of a one-celled animal, which then became a blastocyst, a multi-celled human embryo. These blastocysts are partly made up of an inner mass of cells, and the body of every adult person has developed out of this inner mass. It is this very same clump from the inner part of the blastocyst that consists of source cells for human embryonic stem 1 cell research. These cells can be extracted and grown into a laboratory specimen of extraordinary interest to scientists. Before discussing the significance of the fact that all humans originate from these source cells, it is useful to begin by asking some perhaps rather simple-minded questions about how any one of us knows this fact to be true in the first place. How do I know that I developed from a single cell, and then a blastocyst? In my own case, the main way I know this is that other people have told me so.. (shrink)

ZusammenfassungIm allgemeinen Vorverständnis sind Ethik und Mathematik nahezu disjunkt. Demgegenüber möchte dieser Aufsatz verdeutlichen, dass eine Verhältnisbestimmung der beiden ein eminentes Forschungsdesiderat ist, und zugleich versuchen, erste Schritte zu einer solchen zu unternehmen.SummaryAccording to common sense ethics and mathematics are nearly disjoint. To the contrary, this paper fosters the view that it is highly desirable to develop a relation between these two perspectives and it tries to do first steps towards this goal.

Cette étude vise à trouver comment les futurs enseignants développent la capacité de réflexion par l’auto-évaluation sur leurs portfolios. Bien que le but était d’aider les enseignants en première année de formation à évaluer leurs progrès vers la réalisation des compétences provinciales, plusieurs d’entre eux ont attiré l’attention des chercheurs sur les liens entre leurs artéfacts universitaires et leurs profils personnels. Ce développement a conduit les chercheurs à affiner la finalité du portfolio pour soutenir l’émergence d’une identité professionnelle et au (...) développement des structures pour soutenir cette forme de connaissance de soi. (shrink)

A person sometimes forms moral beliefs by relying on another person''s moral testimony. In this paper I advance a cognitivist normative account of this phenomenon. I argue that for a person''s actions to be morally good, they must be based on a recognition of the moral reasons bearing on action. Morality requires people to act from an understanding of moral claims, and consequently to have an understanding of moral claims relevant to action. A person sometimes fails to meet this requirement (...) when she relies on another person''s moral testimony, and so there are moral limits on such reliance. (shrink)

Some of the systems used in natural language generation (NLG), a branch of applied computational linguistics, have the capacity to create or assemble somewhat original messages adapted to new contexts. In this paper, taking Bernard Williams’ account of assertion by machines as a starting point, I argue that NLG systems meet the criteria for being speech actants to a substantial degree. They are capable of authoring original messages, and can even simulate illocutionary force and speaker meaning. Background intelligence embedded in (...) their datasets enhances these speech capacities. Although there is an open question about who is ultimately responsible for their speech, if anybody, we can settle this question by using the notion of proxy speech, in which responsibility for artificial speech acts is assigned legally or conventionally to an entity separate from the speech actant. (shrink)

Some recent accounts of testimonial warrant base it on trust, and claim that doing so helps explain asymmetries between the intended recipient of testimony and other non-intended hearers, e.g. differences in their entitlement to challenge the speaker or to rebuke the speaker for lying. In this explanation ‘dependence-responsiveness’ is invoked as an essential feature of trust: the trustor believes the trustee to be motivationally responsive to the fact that the trustor is relying on the trustee. I argue that dependence-responsiveness is (...) not essential to trust and that the asymmetries, where genuine, can be better explained without reference to trust. (shrink)

This volume compiles contemporary records of the ancient polemic against stoicism a doctrine whose rigid notions led to perpetual conflict about its image of the world and of man. The texts are arranged according to the nature and mode of their argument against stoicism: skeptical anti-dogmatism, stoical self-critique, satirical parody, polemical rejection, critical distancing, and narrative depiction.".

There is the widely held view that quantum physics differs fundamentally from classical physics regarding measurements. In order to prepare the ground for settling this question we discuss the consequences it has for classical physics if one includes measurement in the theory. After explaining the terms measurement and error it is argued that every measurement can be reduced to a measurement of length and/or number. Additionally to the wellknown statistical and systematical errors we introduce the concept of classical uncertainty which (...) states that every measurement of a physical quantity _A_ carries a finite inaccuracy Δ_A_. Hence it is transempirical to assign an infinite decimal number to a measurement. This implies that, also in classical physics, only probabilistic predictions are possible and that we need ensembles for the empirical testing of theoretical predictions. Furthermore we rebut the claim that in classical physics measurements can be performed without any disturbance of the system under investigation. Finally we state that by including measurements in the theory itself classical physics like quantum physics can be formulated as an indeterministic theory. Likewise both theories can be formulated deterministically if measurements are excluded from the theory. _German_ Gemäß einer weit verbreiteten Sichtweise gibt es hinsichtlich der Messung in der Quantenphysik und in der klassischen Physik einen grundlegenden Unterschied. Um einer Klärung dieser Frage den Boden zu bereiten, versuchen wir für die klassische Physik die Folgen zu diskutieren, die sich ergeben, wenn man die Messung in die Theorie mit einbezieht. Zunächst wird dafür argumentiert, dass jede Messung auf eine Längenbzw. Zählmessung zurückzuführen ist. Wir führen zusätzlich zu den bekannten Arten von Messfehlern – statistischen und systematischen Fehlern – das Konzept der klassischen Messunschärfe ein, das abbildet, dass jede Messung einer Messgröße _A_ mit einer endlichen Ungenauigkeit Δ_A_ behaftet sein muss. Dies bedeutet insbesondere, dass die Angabe von nichtendlichen Dezimalzahlen für Messwerte transempirisch ist. Die Betrachtung der Messfehler führt zu der Folgerung, dass auch in der klassischen Physik nur mehr Wahrscheinlichkeitsaussagen getroffen werden können und Messungen an Ensembles zur empirischen Bestätigung theoretischer Vorhersagen nötig sind. Außerdem wird die Behauptung entkräftet, in der klassischen Physik seien im Prinzip Messungen möglich, die den Zustand eines Systems nicht stören. Abschließend stellen wir heraus, dass durch Einbeziehung der Messung in die Theorie die klassische Physik wie die Quantenphysik als indeterministischen Theorie formuliert werden kann, ebenso wie beide ohne Einbeziehung der Messung deterministisch formuliert werden können. (shrink)

The United States has never been culturally or religiously homogeneous, but its diversity has greatly increased over the last century. Although the U.S. was first a multicultural nation through conquest and enslavement, its present diversity is due equally to immigration. In this paper I try to explain the difference it makes for one area of thought and policy – equal opportunity – if we incorporate cultural and religious pluralism into our national self-image. Formulating and implementing a policy of equal opportunity (...) is more difficult in diverse, pluralistic countries than it is in homogeneous ones. My focus is cultural and religious diversity in the United States, but my conclusions will apply to many other countries – including ones whose pluralism is found more in religion than in culture. (shrink)

Intentionalism is the claim that the phenomenological properties of a perceptual experience supervene on its intentional properties. The paper presents a counter-example to this claim, one that concerns visual grouping phenomenology. I argue that this example is superior to superficially similar examples involving grouping phenomenology offered by Peacocke (Sense and Content, Oxford: Oxford University Press), because the standard intentionalist responses to Peacocke’s examples cannot be extended to mine. If Intentionalism fails, it is impossible to reduce the phenomenology of an experience (...) to its content. (shrink)

According to assurance views of testimonial justification, in virtue of the act of testifying a speaker provides an assurance of the truth of what she asserts to the addressee. This assurance provides a special justificatory force and a distinctive normative status to the addressee. It is thought to explain certain asymmetries between addressees and other unintended hearers (bystanders and eavesdroppers), such as the phenomenon that the addressee has a right to blame the speaker for conveying a falsehood but unintended hearers (...) do not, and the phenomenon that the addressee may deflect challenges to his testimonial belief to the speaker but unintended hearers may not. Here I argue that we can do a better job explaining the normative statuses associated with testimony by reference to epistemic norms of assertion and privacy norms. Following Sanford Goldberg, I argue that epistemic norms of assertion, according to which sincere assertion is appropriate only when the asserter possesses certain epistemic goods, can be ‘put to work’ to explain the normative statuses associated with testimony. When these norms are violated, they give hearers the right to blame the speaker, and they also explain why the speaker takes responsibility for the justification of the statement asserted. Norms of privacy, on the other hand, directly exclude eavesdroppers and bystanders from an informational exchange, implying that they have no standing to do many of the things, such as issue challenges or questions to the speaker, that would be normal for conversational participants. This explains asymmetries of normative status associated with testimony in a way logically independent of speaker assurance. (shrink)

In this paper, I examine the ethics of e - trust and e - trustworthiness in the context of health care, looking at direct computer-patient interfaces (DCPIs), information systems that provide medical information, diagnosis, advice, consenting and/or treatment directly to patients without clinicians as intermediaries. Designers, manufacturers and deployers of such systems have an ethical obligation to provide evidence of their trustworthiness to users. My argument for this claim is based on evidentialism about trust and trustworthiness: the idea that trust (...) should be based on sound evidence of trustworthiness. Evidence of trustworthiness is a broader notion than one might suppose, including not just information about the risks and performance of the system, but also interactional and context-based information. I suggest some sources of evidence in this broader sense that make it plausible that designers, manufacturers and deployers of DCPIs can provide evidence to users that is cognitively simple, easy to communicate, yet rationally connected with actual trustworthiness. (shrink)

Linkage arguments, which defend a controversial right by showing that it is indispensable or highly useful to an uncontroversial right, are sometimes used to defend the right to health care. This article evaluates such arguments when used to defend RHC. Three common errors in using linkage arguments are neglecting levels of implementation, expanding the scope of the supported right beyond its uncontroversial domain, and giving too much credit to the supporting right for outcomes in its area. A familiar linkage argument (...) for RHC focuses on its contributions to the right to life. Among the problems with this argument are that it requires a positive conception of the right to life that is not uncontroversial and that it only justifies the subset of RHC that seeks to prevent loss of life. A linkage argument for RHC with better prospects claims that a well-realized right to health care enhances the realization of a number of uncontroversial rights. (shrink)