Background Antimicrobial resistance (AMR) is a global threat to human and livestock health. Although AMR is driven by use of antimicrobials, it is often attributed to “misuse” and “overuse”, particularly for antibiotics. To curb resistance, there has been a global call to embrace new forms of moral personhood that practice “proper” use, including prescription, dispensing and consumption of antimicrobials, especially antibiotics. This paper seeks to reflect on complex questions about how morality has become embedded /embodied in the AMR discourse as (...) presented in the data collected on antimicrobial prescription, dispensing and use in human and livestock health in Tanzania, primarily focusing on antibiotics. Methods This reflection is anchored on Jarrett Zigon’s morality framework that is comprised of three dimensions of discourse; the institutional, public, and embodied dispositions. The data we use within this framework are derived from a qualitative study targeting human and animal health care service providers and community members in northern Tanzania. Data were collected through 28 in-depth interviews and ten focus group discussions and analysed through content analysis after translation and transcription. In addition, a review of the Tanzania’s National Action Plans on antimicrobial resistance was conducted. Results Application of the framework demonstrates points of convergence and divergence in the institutional morality discourse articulated by the Tanzania National Action Plans, the public discourse and the embodied dispositions/ lived experiences of human and animal health care service providers and community members. We demonstrate that AMR is not just associated with “inappropriate” behaviour on the part of drug prescribers, dispensers, and users but also with shortcomings in health systems and service delivery. Conclusion Antibiotic dispensing and use practices that may be associated with the development of AMR should not be viewed in isolation from the broader health context within which they occur. (shrink)

In Philosophical Fragments the pseudonymous author Johannes Climacus explored the question: What is required in order to go beyond Socratic recollection of eternal ideas already possessed by the learner? Written as an afterword to this work, Concluding Unscientific Postscript is on one level a philosophical jest, yet on another it is Climacus's characterization of the subjective thinker's relation to the truth of Christianity. At once ironic, humorous, and polemical, this work takes on the "unscientific" form of a mimical-pathetical-dialectical compilation of (...) ideas. Whereas the movement in the earlier pseudonymous writings is away from the aesthetic, the movement in Postscript is away from speculative thought. Kierkegaard intended Postscript to be his concluding work as an author. The subsequent "second authorship" after The Corsair Affair made Postscript the turning point in the entire authorship. Part One of the text volume examines the truth of Christianity as an objective issue, Part Two the subjective issue of what is involved for the individual in becoming a Christian, and the volume ends with an addendum in which Kierkegaard acknowledges and explains his relation to the pseudonymous authors and their writings. The second volume contains the scholarly apparatus, including a key to references and selected entries from Kierkegaard's journals and papers. (shrink)

The diffusion of ideas about contemporary terrorism is analyzed using a sociology of science methodology. One of the most common means of creating understandings of a phenomenon is the development and diffusion of ideas that influence the positions adopted by a wide range of actors, including government bureaucrats and decision makers, legislative and corporate bodies, and the public. How did terrorism researchers interact with these actors to construct, maintain, and modify the development and perception of contemporary terrorism? How were the (...) ideas diffused and what impact did they have on policymakers? Did the invisible college of terrorism researchers function as an epistemic community? These questions are analyzed using an integrated research strategy that employs a number of techniques and data sources such as bibliometrics, content analysis, and citation analysis of selected terrorism research publications, biographies, and conferences, and on-line tracing of researchers’ affiliations, participations, and collaborations. (shrink)

Lotman’s contribution to semiotic theory, anthroposemiotics, the study of artistic texts and defining the relationship between language and culture represent some of the most powerful work produced within the Tartu–Moscow School of Semiotics. The importance of translation is one of the central principles that unites all of Lotman’s work. In the following paper, we will consider Lotman’s definition of translatability in the context of (1) the definition of semiospheric internal and external boundaries and the importance of crossing these boundaries, (2) (...) the role of no fewer than two languages as a minimal unit of semiotic meaning-generation, (3) culture text-level generation of collective memory, and (4) the ever-present tension in the communication act. In our concluding section, we will offer an extended model of the communication act, based on the fundamental principles given in Jakobson, Sebeok and Lotman, in order to specify important moments of the translation process. (shrink)

O presente artigo analisa o projeto filosófico de John Dewey (1859-1952) que consta de uma crítica radical à epistemologia tradicional a partir da concepção pragmatista de experiência. O status científico da filosofia, conforme Dewey, não exigirá uma teoria científica passível de prova, mas um programa metafísico construído a partir de lógicas situacionais. O presente artigo apresenta as dimensões históricas e científicas da metafísica empírica de Dewey, argumentando a favor da articulação entre as duas abordagens que configuram o projeto de reconstrução (...) da filosofia. Dewey compreende que a busca dos fundamentos últimos tornou a filosofia prisioneira de uma imagem da mente como construtora de representações - algumas exatas, outras não, mas todas com a pretensão de serem estudadas por meio de métodos puros, não empíricos. Diferentemente dessa tradição que supõe uma ideia de superioridade intelectual do saber, revelado por meio de métodos não empíricos, Dewey argumenta a favor do empírico em filosofia e se coloca contra uma comum concepção da realidade como segura, regular e acabada. Palavras Chave: Experiência. Natureza. Metafísica empírica. Reconstrução filosófica. (shrink)

A memória humana é essencial para a atividade teatral. Isso por um motivo óbvio: é ela que possibilita aos atores gravarem suas falas e ao público compreender a mensagem passada pela peça. Neste trabalho, investigamos as noções de memória propostas por Descartes, Hume e Kohonen. Para eles, a memória é imprescindível na obtenção e desenvolvimento do conhecimento. A nosso ver, o estudo da memória é de grande importância para o teatro, à medida que este não seria possível sem aquela.

Examina a relevância da Lei de Acesso à Informação – LAI na consolidação institucional do Ministério Público Federal - MP no Brasil. Analisa a sua a atuação durante o regime militar e no processo de redemocratização após a Constituição de 1988. Aponta a sua evolução como instituição permanente e essencial à função jurisdicional do Estado, responsável, perante o Judiciário, pela defesa da ordem jurídica e dos interesses indisponíveis da sociedade, assim como seu papel na investigação de fatos nacionais sobre os (...) perpetradores de violações aos direitos humanos. (shrink)

Resumo: Neste artigo, argumentamos a favor de uma versão sofisticada do realismo científico, tendo como eixo norteador a análise do desempenho do que consideramos ser o seu elemento de defesa estratégico: o “argumento do milagre”. O realismo científico é a perspectiva comprometida com as nossas melhores teorias científicas, isto é, com a existência de entidades, processos, relações etc., observáveis ou inobserváveis, indispensáveis para explicar o seu sucesso empírico, em particular, com aqueles componentes das teorias que são cruciais para se alcançar (...) novas previsões bem-sucedidas. O argumento do milagre é um tipo de abdução ou inferência da melhor explicação e se expressa na célebre formulação de Putnam : “O realismo científico é a única filosofia que não faz do sucesso da ciência um milagre.” Analisamos e rebatemos duas importantes modalidades de argumentação antirrealista: a indução pessimista e a circularidade viciosa da inferência da melhor explicação. Acreditamos estar justificados quanto à defesa da intuição básica do realismo científico, com o apoio de uma versão fortalecida e articulada do argumento do milagre, mediante as qualificações de novidade preditiva e fecundidade teórica: a ciência é bem-sucedida em explicar e prever fenômenos, inclusive novos, porque suas melhores teorias são verdadeiras e as entidades inobserváveis postuladas por essas teorias realmente existem. Concluímos que o argumento do milagre continua sendo basilar e estratégico na defesa do realismo científico.: In this article, we argue in favor of a sophisticated version of scientific realism, based on an analysis of what we consider to be the strategic element of its defense: the “miracle argument”. Scientific realism is the perspective applicable to our best scientific theories; that is, it applies to entities, processes, and relationships, etc., whether observable or unobservable, which are indispensable for explaining the empirical success of theories, and it applies particularly to those components of the theories that are crucial to achieving new and successful forecasts. The miracle argument is a type of abduction or inference to the best explanation, and is expressed in the famous formulation of Putnam : “[Scientific] realism is the only philosophy that doesn’t make the success of the science a miracle.” We analyze and refute two important modes of antirealist argument: pessimistic induction and vicious circularity of inference to the best explanation. We believe that we are justified in defending the basic intuition of scientific realism, supported by a strengthened version of the miracle argument, together with the attributes of predictive novelty and theoretical fecundity. From this perspective, science succeeds in explaining and predicting phenomena, including new phenomena, because its best theories are true, and the unobservable entities postulated by these theories actually exist. We conclude that the miracle argument continues to be basic and strategic in the defense of scientific realism. (shrink)

The various kinds and conditions of love are a common theme for Kierkegaard, beginning with his early Either/Or, through "The Diary of the Seducer" and Judge William's eulogy on married love, to his last work, on the changelessness of God's love. Works of Love, the midpoint in the series, is also the monumental high point, because of its penetrating, illuminating analysis of the forms and sources of love. Love as feeling and mood is distinguished from works of love, love of (...) the lovable from love of the unlovely, preferential love from love as the royal law, love as mutual egotism from triangular love, and erotic love from self-giving love. This work is marked by Kierkegaard's Socratic awareness of the reader, both as the center of awakened understanding and as the initiator of action. Written to be read aloud, the book conveys a keenness of thought and an insightful, poetic imagination that make such an attentive approach richly rewarding. Works of Love not only serves as an excellent place to begin exploring the writings of Kierkegaard, but also rewards many rereadings. (shrink)

O objetivo deste artigo foi investigar a leitura neopragmatista de Richard Rorty (1931-2007) sobre a concepção de subjetividade em Michel Foucault (1926-1984). Rorty ficou conhecido como um celebre filósofo que se opôs à concepção moderna de sujeito, sobretudo, o excesso de antropocentrismo e cientificismo. Quanto ao filósofo francês Michel Foucault, pode-se constatar no terceiro domínio de sua produção teórica, a presença de uma investigação vigorosa sobre a constituição do sujeito. Inicialmente, percebe-se desde seus primeiros escritos, o papel que exerce o (...) poder e a verdade enquanto mecanismos criadores de subjetividade, impondo aos sujeitos modos de ser e de relacionar-se consigo e com os outros. Todavia, a análise sobre a questão da constituição do sujeito se configura de forma mais delimitada nos cursos Subjetividade e Verdade (1981) e A Hermenêutica do Sujeito (1982). Foucault desenvolve uma investigação sobre a subjetividade a partir das noções de ética, filosofia, espiritualidade, sexualidade, arte de viver e cuidado de si, buscando compreender como o sujeito torna-se assujeitado pelo poder e saber, sugerindo novos modos de subjetividade, diferentes daqueles propostos pelo poder. Entretanto, contrariamente ao que propôs Foucault, o filósofo norte-americano neopragmatista Richard Rorty, conhecido por propor uma filosofia edificante, afirma na obra Contingência, ironia e solidariedade (2007) que as ideias do filósofo francês, embora tentem se desvencilhar da concepção moderna de subjetividade, ainda se mantêm atreladas a ela. Assim, pretende-se explorar os argumentos rortyanos que justificam às objeções a Foucault, e com base na análise de textos específicos de ambos os autores, se busca identificar os argumentos usados por Rorty para acusar Foucault de permanecer no quadro teórico da modernidade. (shrink)

Assembling the pieces : the neuroscience disciplines essential for the study of language and brain -- Building the basis : linguistic contributions to a theory of language and their relevance to the study of language and brain -- Neuroscience applications to the study of multilingualism -- Exploring the boundaries of cognitive linguistics and neurolinguistics : reimagining cross-cultural contributions -- Imaging technologies in the study of multilingualism : focus on BOLD fMRI -- Reassembling the pieces : languages and brains.

Xenotransplantation, or the use of animal cells, tissues and organs for humans, has been promoted as an important solution to the worldwide shortage of organs. While scientific studies continue to be done to address problems of rejection and the possibility of animal-to-human virus transfer, socio-ethical and legal questions have also been raised around informed consent, life-long monitoring, animal welfare and animal rights, and appropriate regulatory practices. Many calls have also been made to consult publics before policy decisions are made. This (...) paper describes the Canadian public consultation process on xenotransplantation carried out by the Canadian Public Health Association in an arm’s length process from Health Canada, the ministry overseeing government health policy and regulation. Focusing on six citizen fora conducted around the country patterned after the citizen jury deliberative approach, the paper describes the citizen panelists’ recommendations to hold off on proceeding with clinical trials and the rationales behind this recommendation. The consultation process is discussed in the context of constructive technology assessment, a framework which argues for broader input into earlier stages of technology innovation, particularly at the technology design stage. (shrink)

Stem cell tourism is a small but growing part of the thriving global medical tourism marketplace. Much stem cell research remains at the experimental stage, with clinical trials still uncommon. However, there are over 700 clinics estimated to be operating in mostly developing countries – from Costa Rica and Argentina to China, India and Russia – that have lured many patients, mostly from industrialized countries, driven by desperation and hope, which in turn continue to fuel the growth of such tourism.While (...) much research has focused on such dimensions as the promotions that allow such businesses to make their services known, media coverage, some patient research, and regulatory conditions for developing country clinics, little attention has been paid to the non-affected members of the general population, the future potential users of such services. This empirical study based on five focus group discussions with a diverse group of healthy adults in a Canadian city, explored participant views of patients who use stem cell tourism services, the likelihood they would avail themselves of such services if they were to suffer similar illnesses, and the conditions under which they might do so, and the impact that admonitions and advice from international expert bodies might have on their decisions. Our findings suggest that these healthy adults are sympathetic to the drivers of hope and desperation, and, despite cautions about research limitations, may seek such treatments themselves under similar conditions. These findings are discussed in the context of the policy and ethical issues raised by this form of medical tourism. (shrink)

A new generation of climate fiction called Cli-fi has emerged in the last decade, marking the strong consensus that has emerged over climate change. Science fiction’s concept of cognitive estrangement that combines a rational imperative to understand while focusing on something different from our everyday world provides one linkage between climate fiction and science fiction. Five novels representing this genre that has substantial connections with science fiction are analyzed, focusing on themes common across these books: their framing of the climate (...) change problem, their representations of science and scientists, their portrayals of economic and environmental challenges, and their scenarios for addressing the climate challenge. The analysis is framed through Taylor’s ideas of the social imaginary and the sociology of expectations, which proposes that expectations are promissory, deterministic, and performative. The novels illustrate in varying ways the problems attending the science-society relationship, the economic imperatives that have driven the characters’ choices, and the contradictory impulses that define our connections with nature. Such representations provide a picture of the challenges that need to be understood, but scenarios that offer possibilities for change are not as fully developed. This suggests that these books may represent a given moment in the longer trajectory of climate fiction while offering the initial building blocks to reconsider our ways of living so that new expectations and imaginaries can be debated and reconceived. (shrink)

Dewey desenvolveu um programa doutrinário que visa mostrar como o conhecimento se funda na experiência. Essa é a dimensão científico-naturalista da sua obra. Nesse sentido, o seu projeto consiste numa rigorosa argumentação contra as explicações em que a experiência e a natureza são apresentadas com base em distinções arbitrárias. Na obra, Reconstruction in Philosophy [Reconstrução em Filosofia], Dewey desenvolveu seu projeto metafísico de dimensão historicista, propondo uma reconstrução para a filosofia. Em Experience and Nature [Experiência e Natureza], ele apresentou uma (...) visada científica para a metafísica. Nessa obra, Dewey tenta pensar um sistema desenvolvido a partir da aplicação do método científico à filosofia tendo como base uma concepção filosófica da experiência. As concepções de Dewey acerca do conhecimento, do uso inteligente da razão e da natureza social da filosofia concorrem para a constituição de sua concepção de ciência. Nas duas obras fica evidente a sua crítica à noção tradicional de conhecimento como representação da realidade. Contra isso, Dewey passa a designar o conhecimento como um conjunto de “crenças” e “proposições” tomadas como garantias de usos ou assertividade garantida. Dewey se opõe à forma pela qual o problema epistemológico é formulado pela tradição, ou seja, a partir de uma posição realista ingênua no qual o conhecimento é visto como representação, desconsiderando o processo de conexão entre as coisas e entre o conhecedor e as coisas. (shrink)