In this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often‐ugly history of scientific attempts to understand the genetic contributions to human behaviors and social outcomes. They then describe what the current science—including genomewide association studies and polygenic indexes—can and cannot tell us, as well as its risks and potential benefits. They conclude with a discussion of responsible behavior in the context of SBG research. (...) SBG research that compares individuals within a group according to a “sensitive” phenotype requires extra attention to responsible conduct and to responsible communication about the research and its findings. SBG research (1) on sensitive phenotypes that (2) compares two or more groups defined by (a) race, (b) ethnicity, or (c) genetic ancestry (where genetic ancestry could easily be misunderstood as race or ethnicity) requires a compelling justification to be conducted, funded, or published. All authors agree that this justification at least requires a convincing argument that a study's design could yield scientifically valid results; some authors would additionally require the study to have a socially favorable risk‐benefit profile. (shrink)

This article deals with the concept of infinity in classical American philosophy. It focuses on the philosophical and technical developments of infinity in the 19th Century American thinkers Royce and Peirce.

The view that belief is a dyadic relation between a believer and some other object, e.g., a proposition, appears to receive support from the fact that we can infer ‘There is something that Jones believes' from ordinary belief ascriptions such as ‘Jones believes that the tallest man is wise’. On consideration, however, it turns out that even a crude nonrelational view of belief can accommodate this inference. In order to permit the inference the nonrelationalist must read‘ There is something that (...) Jones believes' as equivalent to‘ Jones has a belief. (shrink)

Neuroethics is an interdisciplinary field that arose in response to novel ethical challenges posed by advances in neuroscience. Historically, neuroethics has provided an opportunity to synergize different disciplines, notably proposing a two-way dialogue between an ‘ethics of neuroscience’ and a ‘neuroscience of ethics’. However, questions surface as to whether a ‘neuroscience of ethics’ is a useful and unified branch of research and whether it can actually inform or lead to theoretical insights and transferable practical knowledge to help resolve ethical questions. (...) In this article, we examine why the neuroscience of ethics is a promising area of research and summarize what we have learned so far regarding its most promising goals and contributions. We then review some of the key methodological challenges which may have hindered the use of results generated thus far by the neuroscience of ethics. Strategies are suggested to address these challenges and improve the quality of research and increase neuroscience's usefulness for applied ethics and society at large. Finally, we reflect on potential outcomes of a neuroscience of ethics and discuss the different strategies that could be used to support knowledge transfer to help different stakeholders integrate knowledge from the neuroscience of ethics. (shrink)

In this response I take issue with Professor Ausland’s use of the account of the soul in Republic 4 as a basis for reading Republic 8-9. I believe that the method and assumptions of Republic 4 are pre-dialectical and that Books 8-9 should be read in light of the digressive Books 5-7. By placing greater emphasis on the asymmetry between Book 4 and Books 8-9, the basic assumptions governing the decline of regimes will show themselves to tell a different story (...) of moral experience and moral decomposition than we find in Professor Ausland’s instructive and insightful reading of the dialogue. (shrink)

I apply some of the lessons from quantum theory, in particular from Bell’s theorem, to a debate on the foundations of decision theory and causation. By tracing a formal analogy between the basic assumptions of causal decision theory (CDT)—which was developed partly in response to Newcomb’s problem— and those of a local hidden variable theory in the context of quantum mechanics, I show that an agent who acts according to CDT and gives any nonzero credence to some possible causal interpretations (...) underlying quantum phenomena should bet against quantum mechanics in some feasible game scenarios involving entangled systems, no matter what evidence they acquire. As a consequence, either the most accepted version of decision theory is wrong, or it provides a practical distinction, in terms of the prescribed behaviour of rational agents, between some metaphysical hypotheses regarding the causal structure underlying quantum mechanics. (shrink)

I address two seemingly unrelated topics: the first is the subject and formulation of the hypotheses and the second is the number of hypotheses. On the topic of the subject of the hypotheses, my position is that we are initially given an indefinite monad, a “one”, which is in no case “the one”, “the one itself”, or the form of unity. We are meant to read the hypotheses with the question in mind, “what one is this?” If we do so, (...) we are confronted with strikingly different answers, which, when taken together, point us toward key insights into the nature of intelligibility. On the topic of the number of hypotheses: we are led to expect four, but we are given eight. My position is that we are meant to disarm apparent contradictions between paired hypotheses, especially H1-H2 but also H3-4, 5-6, and 7-8, because doing so will help us further determine the different types of monad Parmenides has in view. In the end, two primary types of monad emerge from the process of disambiguation, namely, form and sensible particular, and we, having differentiated these types of “one”, will have gathered resources for understanding how sensible particulars are grounded in forms. (shrink)

In this paper I call attention to Adam Smith’s 'Considerations Concerning the First Formation of Languages' in order to facilitate understanding Adam Smith from a Darwinian perspective. By ‘Darwinian’ I mean a position that explains differential selection over time through natural mechanisms. First, I argue that right near the start of Wealth of Nations Smith signals that human nature has probably evolved over a very long amount of time. Second, I connect this evidence with an infamous passage on infanticide in (...) The Theory of Moral Sentiments in order to argue that Smith is committed to group selection. Third, I argue that in Dissertation on Languages one can find building blocks for the claim that mind and language co-develop over time. More controversially I claim that in TMS there is a distinction between natural sentiments and moral sentiments. Natural sentiments are evolved (presumably through cultural selection) and moral sentiments are developed (through acculturation within society). Along the way, I argue that this distinction would have improved Darwin’s Descent of Man by blocking a move toward eugenics. (shrink)

Translated Felicia McCarren. Stanford: Stanford UP and Cambridge: Cambridge UP, 1995 (Meridian: Crossing Aesthetics series). Pages: xxiii + 161. Pb: 0 8047 2385 0; 10.95. Hb: 0 8047 2376 I; 25.00. Originally published in French as Musica Ficta (Figures de Wagner). Paris: Christian Bourgois, 1991.

In _Civilization and Its Discontents_, Freud made abundantly clear what he thought about the biblical injunction, first articulated in Leviticus 19:18 and then elaborated in Christian teachings, to love one's neighbor as oneself. "Let us adopt a naive attitude towards it," he proposed, "as though we were hearing it for the first time; we shall be unable then to suppress a feeling of surprise and bewilderment." After the horrors of World War II, the Holocaust, Stalinism, and Yugoslavia, Leviticus 19:18 seems (...) even less conceivable—but all the more urgent now—than Freud imagined. In _The Neighbor_, three of the most significant intellectuals working in psychoanalysis and critical theory collaborate to show how this problem of neighbor-love opens questions that are fundamental to ethical inquiry and that suggest a new theological configuration of political theory. Their three extended essays explore today's central historical problem: the persistence of the theological in the political. In "Towards a Political Theology of the Neighbor," Kenneth Reinhard supplements Carl Schmitt's political theology of the enemy and friend with a political theology of the neighbor based in psychoanalysis. In "Miracles Happen," Eric L. Santner extends the book's exploration of neighbor-love through a bracing reassessment of Benjamin and Rosenzweig. And in an impassioned plea for ethical violence, Slavoj Žižek's "Neighbors and Other Monsters" reconsiders the idea of excess to rehabilitate a positive sense of the inhuman and challenge the influence of Levinas on contemporary ethical thought. A rich and suggestive account of the interplay between love and hate, self and other, personal and political, _The Neighbor_ will prove to be a touchstone across the humanities and a crucial text for understanding the persistence of political theology in secular modernity. (shrink)

À partir du paradigme du cahier des charges imposés par l’ ars aux cmpp de Nouvelle-Aquitaine, l’article témoigne des menaces que font peser les politiques publiques de santé sur les institutions. Il s’agit d’une part de comprendre « l’idéo-logique » qui préside au démantèlement des institutions pour favoriser une conception postmoderne du soin où les institutions sont transformées en prestataires de services ; d’autre part, d’analyser ce glissement progressif de la désinstitutionalisation à la « désinstitution » qui menace les fondements (...) du soin psychique dans ses fonctions de reliance, de créativité, de transformation. Ainsi, l’article s’attache à cerner les effets de cette effraction qui infiltre les institutions, les équipes, jusque dans l’intimité de la rencontre thérapeutique. Cette néo-conception qui dénie ce qu’est la réalité psychique, la souffrance, invite à penser des questions pourtant légitimes de la diversité des pratiques, de la place des familles et de l’inclusion des sujets dans la société. (shrink)

(2005). Wonder in the face of scientific revolutions: Adam Smith on Newton's ‘Proof’ of Copernicanism. British Journal for the History of Philosophy: Vol. 13, No. 4, pp. 697-732. doi: 10.1080/09608780500293042.

Dennett argues that we can be mistaken about our own conscious experience. Despite this, he repeatedly asserts that we can or do have unchallengeable authority of some sort in our reports about that experience. This assertion takes three forms. First, Dennett compares our authority to the authority of an author over his fictional world. Unfortunately, that appears to involve denying that there are actual facts about experience that subjects may be truly or falsely reporting. Second, Dennett sometimes seems to say (...) that even though we may be mistaken about what our conscious experience is, our reports about. (shrink)

We investigate the question of whether one can characterize complexity classes in terms of efficient reducibility to the set of Kolmogorov-random strings . This question arises because and , and no larger complexity classes are known to be reducible to in this way. We show that this question cannot be posed without explicitly dealing with issues raised by the choice of universal machine in the definition of Kolmogorov complexity. What follows is a list of some of our main results.• Although (...) Kummer showed that, for every universal machine U there is a time bound t such that the halting problem is disjunctive truth-table reducible to in time t, there is no such time bound t that suffices for every universal machine U. We also show that, for some machines U, the disjunctive reduction can be computed in as little as doubly-exponential time.• Although for every universal machine U, there are very complex sets that are -reducible to , it is nonetheless true that . • Any decidable set that is polynomial-time monotone-truth-table reducible to is in .• Any decidable set that is polynomial-time truth-table reducible to via a reduction that asks at most f queries on inputs of size n lies in. (shrink)

Two articles on the reduction of chemistry are examined. The first, by McLaughlin (1992), claims that chemistry is reduced to physics and that there is no evidence for emergence or for downward causation between the chemical and the physical level. In a more recent article, Le Poidevin (2005) maintains that his combinatorial approach provides grounding for the ontological reduction of chemistry, which also circumvents some limitations in the physicalist program. †To contact the author, please write to: Department of Chemistry and (...) Biochemistry, UCLA, 607 Charles E. Young Drive East, Box 951569, Los Angeles, CA 90095-1569; e-mail: [email protected]. (shrink)

We investigate whether age profiles of ethnobiological knowledge development are consistent with predictions derived from life history theory about the timing of productivity and reproduction. Life history models predict complementary knowledge profiles developing across the lifespan for women and men as they experience changes in embodied capital and the needs of dependent offspring. We evaluate these predictions using an ethnobiological knowledge assessment tool developed for an off-grid pastoralist population known as Choyeros, from Baja California Sur, Mexico. Our results indicate that (...) while individuals acquire knowledge of most dangerous items and edible resources by early adulthood, knowledge of plants and animals relevant to the age and sex divided labor domains and ecologies (e.g., women’s house gardens, men’s herding activities in the wilderness) continues to develop into middle adulthood but to different degrees and at different rates for men and women. As the demands of offspring on parents accumulate with age, reproductive-aged adults continue to develop their knowledge to meet their children’s needs. After controlling for vision, our analysis indicates that many post-reproductive adults show the greatest ethnobiological knowledge. These findings extend our understanding of the evolved human life history by illustrating how changes in embodied capital and the needs of dependent offspring predict the development of men’s and women’s ethnobiological knowledge across the lifespan. (shrink)

Rosenberg's The Thinking Self also takes Husserl to task. Without going into the details here, Rosenberg finds Husserl's reliance on retentions to be inadequate. Instead, Rosenberg proposes that previous representations enter into our unified, instantaneous awareness of a succession as ones of which we are aware that we are, or were, aware of; as items of so-called meta-awareness. But this account falls prey to the same worries as Husserl's. For again, it is by no means clear what a series of (...) awarenesses, meta-awarenesses, meta-meta-awarenesses, etc. have to do with the representation of a temporal series. (shrink)

In Planned Parenthood v. Casey the Court argued that the Fourteenth Amendment protected “choices central to personal dignity and autonomy”. In...

The time?honored concept of change seems capable of accounting for the appearance of matter from the primal energy of the Universe, and in turn for the emergence of life from that matter. As sentient beings, we, perhaps along with other advanced life forms in the cosmos, have become the collective consciousness of the Universe. Our raison d'etre is our ability to appreciate the cosmos?to wonder, to introspect, to abstract, to explain?for technological intelligence is a preeminently evolved agent of the Universe.