Parkinson's Disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time. Early in the disease, the most obvious are shaking, rigidity, slowness of movement, and difficulty with walking. Doctors do not know what causes it and finds difficulty in early diagnosing the presence of Parkinson’s disease. An artificial neural network system with back propagation algorithm is presented in this paper for helping doctors in identifying (...) PD. Previous research with regards to predict the presence of the PD has shown accuracy rates up to 93% [1]; however, accuracy of prediction for small classes is reduced. The proposed design of the neural network system causes a significant increase of robustness. It is also has shown that networks recognition rates reached 100%. (shrink)

Many African scholars have expressed varied thoughts about the concept of a person, specifically about that which constitutes a person in African philosophy. These philosophers include Kwasi Wiredu, Kwame Gyekye and Segun Gbadegesin. What they have in common, though, is that their ideas on the concept of a person issue largely from the traditional philosophies of some West African peoples. Wiredu and Gyekye reflect on Akan conceptions while Gbadegesin carries out his discussions from the Yoruba cultural perspective. This paper examines (...) the thoughts of these prominent philosophers, with a particular focus on the constitution of the person and the nature of his or her destiny. (shrink)

The classical utilitarian legacy of Jeremy Bentham, J. S. Mill, James Mill, and Henry Sidgwick has often been charged with both theoretical and practical complicity in the growth of British imperialism and the emerging racialist discourse of the nineteenth century. But there has been little scholarly work devoted to bringing together the conflicting interpretive perspectives on this legacy and its complex evolution with respect to orientalism and imperialism. This volume, with contributions by leading scholars in the field, represents the first (...) attempt to survey the full range of current scholarly controversy on how the classical utilitarians conceived of 'race' and the part it played in their ethical and political programs, particularly with respect to such issues as slavery and the governance of India. The book both advances our understanding of the history of utilitarianism and imperialism and promotes the scholarly debate, clarifying the major points at issue between those sympathetic to the utilitarian legacy and those critical of it. (shrink)

Consumers occasionally buy commodity products without much thought but purchase high involvement products or services after rigorous information collection and detailed comparisons of the different options. At the core, research on consumer behavior comprises studies on the cognitive processes involved in consumer purchasing decisions and the way buying decisions are made. The discipline of consumer research and marketing has remained dominated by positivist, empiricist, and realist philosophies. Since consumer behaviour is a social phenomenon, the researchers have used logical positivist and (...) interpretivist philosophies to study and develop various theories about consumer behaviour. However, both of these philosophies have inherent limitations to capture the complete knowledge of consumer reality. Pragmatist philosophy is capable of providing solutions to real-life problems by starting with research question and exploring the issues from multiple perspectives. It is, therefore, suggested to explore the various aspects of consumer behaviour research from a pragmatist perspective and contribute more effective information to the body of knowledge in this discipline. (shrink)

Mu‘allâkâtların, tefsir, nahiv, sarf ve dil ilimlerindeki önemli rolünün yanı sıra Arap dili ve edebiyatı âleminde de yüksek ve önemli bir konumu bulunmaktadır. Cahiliye devri müfredatlarının pek çoğunu kapsamasından ötürü dil ve edebiyat erbabı ona önem atfetmiştir. Onlardan biri de, ‘Şerhü’l-Kasâ’idi’l-السبع’ adıyla el-Muâ‘llekât’a yaptığı şerhiyle Ebu Bekir Muhammed bin el-Kasım bin Beşar bin el-Anbari. Bu eserinde pek çok nahiv, zamirin aidiyeti, harflerin manası, zarf ile car ve mecrûrun bağlı olduğu yerin belirlenmesi, müfredatlarıni‘râbı, illetler arasındaki üstünlükler, kıyasa ve luğatta asıl olana, (...) kelimenin irabını belirlemede bazı seslerin etki nedenlerine, sarf, lügat, belağat, eleştiri vb. konulara değinmektedir. Bu itibarla bu araştırma, betimsel analitik yöntemini kullanarak et-Anbari’ninMu‘allâkât şerhindeki nahiv yöntemini, Arap nahiv ilminde iki önemli konu olan kıyas ve ta‘lîl ile ilgili duruşunu açıklayarak değerlendirmeyi hedeflemektedir. (shrink)

Democracy is a political system that has some universal appeal, and, this seems to invest it with some kind of legitimacy over other systems of government. But this in no way suggests that it is homogenously conceived or practiced across the world—particularly in Western and African countries. Yet there is some supposition that some cultures have (almost) perfected their practice of democracy while others are learning its rudiments. This tends to arouse the philosopher's interest in the conceptual and practical bases (...) for the supposition. In African philosophy, the notion of consensus has often been touted as a kernel and mēnsūra for evidence of democracy in traditional African thought. This paper examines the propriety of this move, taking into account the specific positions of the Ghanaian philosophers, Kwasi Wiredu and Kwame Gyekye. It explores the political dynamics of contemporary Africa and brings out the challenges and prospects for the sort of democracy that is being practiced—or, at least, is said to be practiced—in Africa. It is often debated in African political thought whether consensus or majoritarian rule (characterized by such activities as voting and multipartism) defines democracy, but the paper argues that neither of them really brings about democracy. It then highlights the humanistic end of democracy. Using the Ghanaian experience especially, the paper proposes ways of improving the understanding and practice of democracy in Africa. (shrink)

This paper explores how moderate communitarianism could bring about a greater sense of political morality in the practice of democracy in contemporary Africa. Moderate communitarianism is a thesis traceable to Kwame Gyekye, the Akan philosopher. This thesis is a moderation of the infl uence of the community in the Akan, an African social structure. In ensuring good political morality in the Akan, and therefore the African community, Gyekye proposes moral revolution over the enforcement of the law. I perform two main (...) tasks in this article: I reinforce the view that in a democratic framework, moderate communitarianism offers lessons on political morality, and I challenge the notion that moral revolution has greater prospects for bringing about political morality than law enforcement. (shrink)

The age-old philosophical problem of evil, especially prominent in Western philosophy, as resulting from the intellectual irreconcilability of some appellations of God with the presence of evil – indeed, of myriads of evil – in the world, has been debated upon by many African religious scholars; particularly, philosophers. These include John Mbiti, Kwasi Wiredu, Kwame Gyekye, E. B. Idowu and E.O. Oduwole. While the debate has often been about the existence or not of the problem of evil in African theology, (...) not much philosophical discussion has taken place regarding death and its implications for African conception(s) of God. This paper attempts to contribute to the discussion of those implications. It explores the evilness of death, as exemplified in the African notion of “evil death,” and argues that the phenomenon of death presents itself in complex but interesting ways that do not philosophically ground its characterization as evil. Therefore, the problem of evil would not arise in African thought on account of the phenomenon of death. (shrink)

Submission: February 21, 2018 Acceptance: May 23, 2018 Author : Dr Hasskei M. Majeed Title: Reincarnation: A Question in the African Philosophy of Mind Publisher: UNISA Press Pages: 275 Year of Publication : 2017 Reviewer: Ada AGADA, Ph.D. Email : [email protected].

With postmodern societies placing a strong emphasis on making full use of one’s time, it is increasingly common to extol busy individuals as more achieving. In this context, although feeling a social expectation to be busy might imply that individuals are regarded as competent and desirable, its accompanying stressors may also detrimentally impact their mental health. Utilising data from a seven-day diary study, the current research examined the relationship between people’s daily perceived pressure to be busy and their daily emotional (...) wellbeing. Multilevel modelling revealed that daily social pressure to be busy was a significant predictor of daily negative affect, anxiety, and depressive symptoms at the within-person level. Of import, individuals’ trait emotional complexity acceptance moderated these relationships, with those lower on emotional complexity acceptance reporting significantly higher negative affect, anxiety, and depressive symptoms on days they felt greater social pressure to be busy. These effects were not observed among those higher on emotional complexity acceptance. Together, the current findings suggest that social pressure to feel busy is generally related to poorer daily emotional wellbeing, and that those with higher trait emotional complexity acceptance have an advantage of maintaining their emotional wellbeing in the face of such a social pressure. (shrink)

Mu‘allâkâtların, tefsir, nahiv, sarf ve dil ilimlerindeki önemli rolünün yanı sıra Arap dili ve edebiyatı âleminde de yüksek ve önemli bir konumu bulunmaktadır. Cahiliye devri müfredatlarının pek çoğunu kapsamasından ötürü dil ve edebiyat erbabı ona önem atfetmiştir. Onlardan biri de, ‘Şerhü’l-Kasâ’idi’l-السبع’ adıyla el-Muâ‘llekât’a yaptığı şerhiyle Ebu Bekir Muhammed bin el-Kasım bin Beşar bin el-Anbari. Bu eserinde pek çok nahiv, zamirin aidiyeti, harflerin manası, zarf ile car ve mecrûrun bağlı olduğu yerin belirlenmesi, müfredatlarıni‘râbı, illetler arasındaki üstünlükler, kıyasa ve luğatta asıl olana, (...) kelimenin irabını belirlemede bazı seslerin etki nedenlerine, sarf, lügat, belağat, eleştiri vb. konulara değinmektedir. Bu itibarla bu araştırma, betimsel analitik yöntemini kullanarak et-Anbari’ninMu‘allâkât şerhindeki nahiv yöntemini, Arap nahiv ilminde iki önemli konu olan kıyas ve ta‘lîl ile ilgili duruşunu açıklayarak değerlendirmeyi hedeflemektedir. (shrink)

Hepatocellular carcinoma (HCC) presents a significant problem that necessitates a greater understanding of its underlying molecular complexity in order to improve diagnostics and therapies. Recent studies have shed light on the critical role that mitochondrial dysfunction plays in the development and course of HCC. Once thought to be primarily involved in the synthesis of cellular energy, mitochondria are now known to be key participants in the regulation of a variety of cellular functions that go beyond bioenergetics. The purpose of this (...) review is to elucidate the diagnostic and therapeutic implications of mitochondrial dysfunction in HCC by synthesising ideas from conventional and contemporary scientific literature. Within diagnostics, the discovery of mitochondrial biomarkers such as mutations in mitochondrial DNA and abnormalities in respiratory chain complex activities provides a state-of-the-art viewpoint for the timely identification and accurate description of HCC. In addition, non-invasive imaging methods that focus on mitochondrial function offer prospective means of improving clinical diagnostic accuracy. Moving on to treatment, a growing area of study investigates how mitochondria-targeted therapies might be used to treat HCC. Novel substances and repurposed medications with the potential to induce selective apoptosis in cancer cells, reduce oxidative stress, and restore mitochondrial homeostasis are highly promising. In the fight against hepatocellular carcinoma, an understanding of the complex interactions between mitochondrial dysfunction and HCC opens new diagnostic opportunities and paves the way for individualised treatment plans. (shrink)

Introduction: The Dutch Euthanasia Act states that euthanasia is not punishable if the attending physician acts in accordance with the statutory due care criteria. These criteria hold that: there should be a voluntary and well-considered request, the patient’s suffering should be unbearable and hopeless, the patient should be informed about their situation, there are no reasonable alternatives, an independent physician should be consulted, and the method should be medically and technically appropriate. This study investigates whether physicians experience problems with these (...) criteria in medical practice.Methods: In 2006, questionnaires were sent to a random, stratified sample of 2100 Dutch physicians . Physicians were asked about problems in their decision-making related to requests for euthanasia or assisted suicide after enforcement of the 2002 Euthanasia Act.Results: Of all physicians who had received a request for euthanasia or assisted suicide , 25% had experienced problems in the decision-making with regard to at least one of the criteria of due care. Physicians who had experienced problems mostly indicated to have had problems related to evaluating whether or not the patient’s suffering was unbearable and hopeless and whether or not the patient’s request was voluntary or well considered .Discussion: Physicians in The Netherlands most frequently reported problems related to aspects in which they have to evaluate the patient’s subjective perspective. However, it can be questioned whether placing emphasis on these subjective aspects is an adequate fulfilment of the duties imposed on physicians, as laid down in the Dutch Euthanasia Act. (shrink)

The notion of patients’ duties has received periodic scholarly attention but remains overwhelmed by attention to the duties of healthcare professionals. In a previous paper the author argued that patients in publicly funded healthcare systems have a duty to participate in clinical research, arising from their debt to previous patients. Here the author proposes a greatly extended range of patients’ duties grounding their moral force distinctively in the interests of contemporary and future patients, since medical treatment offered to one patient (...) is always liable to be an opportunity cost in terms of medical treatment needed by other patients. This generates both negative and positive duties. Ten duties—enjoining obligations ranging from participation in healthcare schemes to promoting one’s own earliest recovery from illness—are proposed. The characteristics of these duties, including their basis, moral force, extent and enforceability, are considered. They are tested against a range of objections—principled, societal, epistemological and practical—and found to survive. Finally, the paper suggests that these duties could be thought to reinforce a regrettably adversarial characteristic, shared with rights-based approaches, and that a preferable alternative might be sought through the notion of a “virtuous patient” contributing to a problem-solving partnership with the clinician. However, in defining and giving content to that partnership, there is a clear role for most, if not all, of the proposed duties; their value thus extends beyond the adversarial context in which they might first be thought to arise. (shrink)

In terms of intervening in embodied experience, medical treatment is wonder-full in its ambition and its metaphysical presumption; yet, wonder’s role in clinical medicine has received little philosophical attention. In this paper, I propose, to doctors and others in routine clinical life, the value of an openness to wonder and to the sense of wonder. Key to this is the identity of the central ethical challenges facing most clinicians, which is not the high-tech drama of the popular conceptions of medical (...) ethics but, rather, the routine of patients’ undramatic but unremitting demands for the clinician’s time and respectful attention. Wonder (conceived as an intense and transfiguring attentiveness) is a ubiquitous ethical source, an alternative to the more familiar respect for rational autonomy, a source of renewal galvanizing diagnostic imagination, and a timely recalling of the embodied agency of both patient and clinician. (shrink)

Patients participating in the shared benefits of publicly funded health care enjoy the benefits of treatments tested on previous patients. Future patients similarly depend on treatments tested on present patients. Since properly designed research assumes that the treatments being studied are—so far as is known at the outset—equivalent in therapeutic value, no one is clinically disadvantaged merely by taking part in research, provided the research involves administering active treatments to all participants. This paper argues that, because no other practical or (...) moral considerations count decisively against so doing, we could and should oblige patients to agree to receive indicated treatment within the terms of any concurrent research protocols. This ensures their treatment will benefit not only themselves but also future patients through contributing to new knowledge. By analogy with the paying of income tax, patients should not be allowed to “veto” their social responsibility to take part in clinical research. (shrink)

One of the dominant themes of the symposium from which this collection of articles arose was the ontological status of consent. Is consent a particular state of mind? Is it the signification of that state of mind via a conventionally recognized act? Or, is consent a normative concept that evaluates not only the presence of a state of mind or act, but also the appropriateness of that state of mind or act in the particular circumstances?

Medical screening is justified on the strength of the assumption that the earlier disease is detected, the better it is for the patient. On examination, however, the assumption turns out to be severely flawed, and inadequate anyway, since it is not only the patient with whom we should be concerned, but healthy people as well. Instead of making assumptions about the ill, we should prove a test's overall benefit to the individual taking it before we recommend it.

In this paper I hope to show that a particular modern approach to Aristotle's philosophy of mind is untenable and, out of that negative discussion, develop some tentative suggestions concerning the interpretation of two famous and puzzling Aristotelian maxims. These maxims are, first, that the soul is the form of the body and, second, that perception is the reception of form without matter. The fashionable interpretation of Aristotle which I wish to criticize is the attempt to assimilate him to certain (...) modern philosophies of mind by making him into a functionalist. I shall therefore begin by explaining this modern term of art. (shrink)

I will divide my discussion into two. In the first part I will discuss Godin and Gingras's delicious claim that the experimenter's regress is anticipated by Sextus Empiricus's formulation of scepticism. In the second part, I will try to deal with Godin and Gingras's ‘critical argument’, that the experimenter's regress would be redundant if we were less concerned with ‘frightening philosophers’.

In studying the thinkers discussed, we have generally used (translations of) their writings. The very breadth of this study makes one dependent upon ...

The International Classification of Functioning, Disability and Health (ICF), designed by the WHO, attempts to provide a holistic model of functioning and disability by integrating a medical model with a social one. The aim of this article is to analyze the ICF’s claim to holism. The following components of the ICF’s complexity are analyzed: (1) health condition, (2) body functions and structures, (3) activity, (4) participation, (5) environmental factors, (6) personal factors, and (7) health. Although the ICF claims to be (...) holistic, it presupposes a monistic materialistic ontology. We indicate some limitations of this ontology, proposing instead: (a) a pluralistic–holistic ontology (PHO) and (b) a multidimensional view of the human being, with individual and environmental aspects, in relation to three levels of reality implied by the PHO. For the ICF to attain its holistic claim, the interactions between its components should be based on (a) and (b). (shrink)

Spinoza speculated on how ethics could emerge from biology and psychology rather than disrupt them and recent evidence suggests he might have gotten it right. His radical deconstruction and reconstruction of ethics is supported by a number of avenues of research in the cognitive and neurosciences. This paper gathers together and presents a composite picture of recent research that supports Spinoza’s theory of the emotions and of the natural origins of ethics. It enumerates twelve naturalist claims of Spinoza that now (...) seem to be supported by substantial evidence from the neurosciences and recent cognitive science. I focus on the evidence provided by Lakoff and Johnson in their summary of recent cognitive science in Philosophy in the Flesh: The Embodied Mind and Its Challenge to Western Thought (1999); by Antonio Damasio in his assessment of the state of affective neuroscience in Descartes’ Error (1994) and in The Feeling of What Happens (1999) (with passing references to his recent Looking for Spinoza (2003); and by Giacomo Rizzolatti, Vittorio Gallese and their colleagues in the neural basis of emotional contagion and resonance, i.e., the neural basis of primitive sociality and intersubjectivity, that bear out Spinoza’s account of social psychology as rooted in the mechanism he called attention to and identified as affective imitation. (shrink)

Rapid advancements in machine learning techniques allow mass surveillance to be applied on larger scales and utilize more and more personal data. These developments demand reconsideration of the privacy-security dilemma, which describes the tradeoffs between national security interests and individual privacy concerns. By investigating mass surveillance techniques that use bulk data collection and machine learning algorithms, we show why these methods are unlikely to pinpoint terrorists in order to prevent attacks. The diverse characteristics of terrorist attacks—especially when considering lone-wolf terrorism—lead (...) to irregular and isolated footprints. The irregularity of data affects the accuracy of machine learning algorithms and the mass surveillance that depends on them which can be explained by three kinds of known problems encountered in machine learning theory: class imbalance, the curse of dimensionality, and spurious correlations. Proponents of mass surveillance often invoke the distinction between collecting data and metadata, in which the latter is understood as a lesser breach of privacy. Their arguments commonly overlook the ambiguity in the definitions of data and metadata and ignore the ability of machine learning techniques to infer the former from the latter. Given the sparsity of datasets used for machine learning in counterterrorism and the privacy risks attendant with bulk data collection, policymakers and other relevant stakeholders should critically re-evaluate the likelihood of success of the algorithms and the collection of data on which they depend. (shrink)

Introduction In 2007, a national review committee was instituted in The Netherlands to review cases of active ending of life for newborns. It was expected that 15–20 cases would be reported. To date, however, only one case has been reported to this committee. Reporting is essential to obtain societal control and transparency; the possible explanations for this lack of reporting were therefore explored. Methods Data on end-of-life decision-making were scrutinised from Dutch nation-wide studies (1995, 2001 and 2005), before institution of (...) the committee. Physicians received a questionnaire about their medical decision-making for stratified samples of deceased infants up to 1 year, drawn from the central death registry. Results In 2005, 58% of all deaths were preceded by an end-of-life decision, compared with 68% in 2001 and 62% in 1995. The use of drugs with a possible life-shortening effect tended to be lower. In 2005, all four cases in the study in which an infants' life was actively ended were preceded by a decision to forego life-prolonging treatment. In three cases, the infant's life expectancy was short; one case involved a longer life expectancy. Discussion The expected number of cases is probably an overestimation due to changes in medical practice such as the tendency to attribute less life-shortening effects to opioids. The lack of reports is probably also associated with requirements in the regulation; it may be difficult to fulfil them due either to time constraints or the nature of the suffering that is addressed. If societal control of active ending of life is considered useful, changes in the regulation may be needed. (shrink)

Objectives: This study investigated Finnish physicians’ experiences of decisions concerning living wills and do not resuscitate orders and also their views on the role of patients and family members in these decisions.Design: A questionnaire was sent to 800 physicians representing the following specialties: general practice ; internal medicine ; neurology , and oncology .Results: The response rate was 56%. Most of the respondents had a positive attitude toward , and respect for living wills, and 72% reported situations in which such (...) a will would have been helpful, although experience with their use was limited. The physicians reported both benefits and problems with living wills. Thirteen per cent had completed a living will of their own. Half did not consider living wills to be reliable if they were several years old. Do not resuscitate orders were interpreted in two ways: resuscitation forbidden or only palliative care required . The respondents also documented DNR orders differently. Seventy two per cent discussed DNR decisions always or often with patients able to communicate, and even 76% discussed DNR orders with the family members of patients unable to communicate. Most respondents were able to approach a dying patient without difficulty. They also felt that education in general was needed.Conclusions: In general Finnish physicians accept living wills, but find they are accompanied by several problems. Many problems could be avoided if physicians and patients conducted progressive discussions about living wills. The differing interpretations of DNR orders are a matter of concern in that they may affect patient treatment. The promotion of patient autonomy with respect to treatment seems rather good, but the limitations of the study need to be kept in mind. (shrink)