This paper presents a platform for developing, testing and executing synchronous collaborative applications in a distributed, heterogeneous environment. Even though several environments exist nowadays, specific problems are not treated satisfactorily. Especially in ‘real’ network environments, problems like unstable network connections and low bandwidths have to be considered.The DreamTeam platform addresses the special needs of environments with non-optimal characteristics which can, be found in distance learning scenarios. DreamTeam comprises a development environment, a simulation environment and a runtime environment; it is based (...) upon the concept of a fully decentralised architecture and encourages rapid prototyping.DreamTeam supports developers of shared applications through a component concept. Using components helps to divide a software project into well-defined parts. Well-documented interfaces help to reduce integration efforts and improve software quality. A selection of sample applications with DreamTeam validates our design concept. (shrink)

Whereas the Upanishads contain much which is, strictly speaking, of little interest to the historian of Indian thought, the Pre-Upanishadic texts are not completely devoid of passages which are of special importance for anyone who endeavours to trace the origin and oldest form of the main texts of classical Indian philosophy. Too often the difference between Upanishads and Pre-Upanishadic literature has been exaggerated ; too often the philosophical importance of the ritualistic speculations contained in the Brahmanas has been undervalued ; (...) too often these texts have been neglected by the compilers of handbooks. One of those points which have not always received due attention concerns the theoretic foundation of the belief in the possibility of gaining the victory over death and of the efforts to realize this ambition. One of the most important problems in which the Indians have always been interested is the relation between the One and the Many, between this phenomenal world and its source and ground. Already in the Rgveda opinions differ : it has been a divine architect who made the phenomenal world ; it has been an anonymous primeval deity who became a golden germ from which a demiurge was born ; the world has arisen from the impersonal One who desired to create the world, etc. In the course of time these creators and ideas of the original One fused into the great figure of Prajapati, „the Lord of Creatures”. This God, who occupies a central position in the Brdhmawa-texts originally was what he was to remain in popular belief : the deity presiding over biological creation. In the ritualistic speculations of the authors of the Brahmanas he is the Creator, the Father of gods and anti-gods, the origin of creation. In the beginning Prajapati was alone, he was ,all this’, he was the universe in ,concentrated’ and unmanifested form. By way of emanation and self-differentiation he became the manifested universe, including the creatures. After this creative activity he is empty and exhausted, because he has ,entered the universe' or rather transformed himself into the universe. His strength, force and health can however be recovered and restored by means of rites. The world and the creatures which emanated from Prajapati were not perfect ; they were a discontinuum, disintegrated, in the power of death. In order to make life possible and to make the world habitable Prajdpati instituted rites. Prajapati is in the Brahmanas identified with the highest and most general categories ; he is the year, i.e. the complete cycle of time comprising the past and the future, totality and completeness. The year, viewed as an integral structure is the fundamental basis of all that happens. Being also the rite, the sacral act, Prajapati is on the other hand the earthly counterpart of the great cosmic drama. On these two identifications the ritualistic system of these authors is constructed. Among these authorities Sandilya. occupies a prominent place. The mundane events oscillating between the poles of birth and death, of genesis and decay, rites are needed to reintegrate what has become decomposed. They are however also to restore the original unity and totality, to co-ordinate the non-co-ordinated phenomena, to reconstruct Prajapati, to restore his original oneness. The rites reduce, temporarily it is true and with regard to the individual who has them performed, the phenomenal multiplicity to a reintegrated totality, in which the diversity of Prajapati's emanation has been destroyed, and the original unity and oneness has been restored. This theory underlies the structure of the great Fire-altar , by which the sacrificer identifies himself with Prajapati whose original unity is restored. By performing this elaborate ritual the personality of the sacrificer was transformed into a new and divine existence, which was no longer subject to the imperfections proper to this world. That is to say : the sacrificer acquires ,immortality' , he transcends the limits of phenomenal time, he becomes sarva, i.e. safe-andsound, whole. Prajapati-the year will not destroy the man who identifies himself with the totality, with Prajapati-the year, and who has acquired an insight into the meaning of this identification ; that man overcomes disintegration and discontinuity, he gains the victory over death, that is to say : he attains to a sound and complete condition. In the course of time the personal Prajapati and the impersonal Brahman are identified. In the early Upanishads the latter becomes the great fundamental principle. These works resume on the one hand ancient speculations a part of which has been preserved in the Rg- and Atharvavedas, and utilize, on the other hand, the ritualistic theories of the Brdhmawas. The tendency of their authors is however to dissociate themselves from ritualism. Emphasizing the quest for the salvation and spiritual welfare of the individual they go into the problem of the ,Soul' , that is the ,self' or the very core of the personality, which is essentially different from all phenomenal plurality. The hitman is identified with the Punira, the primeval man out of whom the universe arose. It follows that the Atrmn is also cosmic. According to Udddlaka Arum it is the subtle essence of all that exists. All the important potencies in the universe are said to be its manifestations. However, in these works . Htman and Brahman tend to fuse and the great teacher Ydjwavalkya concluded to their being identical. Ordinary men do not understand this identity, but the few who are able to arrive at this highly important insight gain the victory over the imperfections and contingencies of empirical existence. They experience the ecstatic and unanalysable condition of unity, the undifferentiated Plenum or Totality, the ,All'. They know that they are truly Brahman or Sarvam. Now, it is most important to attain to this condition, which implies the victory over death, before one is to die the worldly death. The man who dies without having escaped death will die again and again in the hereafter. Whereas the ritualists attempt to protect themselves from this much feared ,repeated death' by means of rites, especially by the construction of the Fire-altar, the teachers whose words are recorded in the early Upanishads ascribed the delivering power to the esoteric knowledge of the ,under lying theory', to the knowledge of the ritual-cosmic interrelations : the man who knows the relevant speculations will be released. This belief in the redeeming power of the rites and the ,theory' on which they are based was also of special importance with regard to the development of the Karman-doctrine. Thus ritual and spiritual identification with the One which is the Totality, the Primeval Being, the Creator, the Atman enables man by experiencing a transformation to conquer phenomenal time and death. (shrink)

Genomic sequencing technologies (GS) pose novel challenges not seen in older genetic technologies, making traditional standards for fully informed consent difficult or impossible to meet. This is due to factors including the complexity of the test and the broad range of results it may identify. Meaningful informed consent is even more challenging to secure in contexts involving significant time constraints and emotional distress, such as when rapid genomic testing (RGS) is performed in neonatal intensive care units. In this article, we (...) propose that informed consent matters not for its own sake, but because obtaining it furthers a range of morally important goals, such as promoting autonomy, well‐being, and trust in medicine. These goals form the basis of a new framework [PROmoting Morally Important Consent Ends (PROMICE)] for assessing the ethical appropriateness of various informed consent models. We illustrate this framework with two examples: (a) a tiered and layered consent model for obtaining consent for GS, and (b) consent for RGS in critically ill newborns. We conclude that appropriately—rather than fully—informed consent provides the correct standard for genomic medicine and research. (shrink)

Schon seit ihrer Gr ndung in den 1970er-Jahren ist die Reihe Germanistische Linguistik (RGL) exponiertes Forum des Faches, dessen Namen sie im Titel f hrt. Hinsichtlich der thematischen Breite (Sprachebenen, Variet ten, Kommunikationsformen, Epochen), der Forschungsperspektiven (Theorie und Empirie, Grundlagenforschung und Anwendung, Inter- und Transdisziplinarit t) und des methodologischen Spektrums ist die Reihe offen angelegt. Das Aufgreifen neuer Trends hat in ihr ebenso Platz wie das Fortf hren von Bew hrtem. Die Publikationsformen reichen von Monographien und Sammelb nden bis zu (...) W rterb chern. Wissenschaftlicher Beirat (ab November 2011): Prof. Dr. Karin Donhauser (Berlin) Prof. Dr. Stephan Elspa (Augsburg) Prof. Dr. Helmuth Feilke (Gie en) Prof. Dr. J rg Fleischer (Marburg) Prof. Dr. Stephan Habscheid (Siegen) Prof. Dr. R diger Harnisch (Passau). (shrink)

We study the problem of existence and generic existence of ultrafilters on ω. We prove a conjecture of $J\ddot{o}rg$ Brendle's showing that there is an ultrafilter that is countably closed but is not an ordinal ultrafilter under CH. We also show that Canjar's previous partial characterization of the generic existence of Q-points is the best that can be done. More simply put, there is no normal cardinal invariant equality that fully characterizes the generic existence of Q-points. We then sharpen results (...) on generic existence with the introduction of $\sigma-compact$ ultrafilters. We show that the generic existence of said ultrafilters is equivalent to $\delta = c$ . This result taken along with our result that there exists a $K_{\sigma}$ non-countably closed ultrafilter under CH, expands the size of the class of ultrafilters that were known to fit this description before. From the core of the proof, we get a new result on the cardinal invariants of the continuum, i.e., the cofinality of the sets with $\sigma-compact$ closure is δ. (shrink)

What are physical quantities, and in particular, what makes them quantitative? This book presents an original answer to this question through the novel position of substantival structuralism, arguing that quantitativeness is an irreducible feature of attributes, and quantitative attributes are best understood as substantival structured spaces.

For half a century, J. I. Packer's classic has helped Christians everywhere discover the wonder, glory, and joy of knowing God. This fiftieth anniversary edition of a thought-provoking work seeks to renew and enrich our understanding of God, bringing together knowing about God and knowing God through a close relationship with Jesus Christ.

International array of contributors, bringing together both traditional and more recent approaches to provide valuable insights into the poets’ use of language.Covers authors from Lucilius to Juvenal.Of the peoples of ancient Italy, only the Romans committed newly composed poems to writing, and for 250 years Latin-speakers developed an impressive verse literature.The language had traditional resources of high style, e.g., alliteration, lexical and morphological archaism or grecism, and of course metaphor and word order; and there were also less obvious resources in (...) the technical vocabularies of law, philosophy and medicine.The essays in this volume show how the poets in the classical period combined these elements, and so created a poetic medium that could comprehend satire, invective, erotic elegy, drama, lyric, and the grandest heroic epos. (shrink)

Prologue: Stormclouds : London, April 1900 -- Quantum of action: The most strenuous work of my life : Berlin, December 1900 ; Annus Mirabilis : Bern, March 1905 ; A little bit of reality : Manchester, April 1913 ; la Comédie Française : Paris, September 1923 ; A strangely beautiful interior : Helgoland, June 1925 ; The self-rotating electron : Leiden, November 1925 ; A late erotic outburst : Swiss Alps, Christmas 1925 -- Quantum interpretation: Ghost field : Oxford, August (...) 1926 ; All this damned quantum jumping : Copenhagen, October 1926 ; The uncertainty principle : Copenhagen, February 1927 ; The 'Kopenhagener geist' : Copenhagen, June 1927 ; There is no quantum world : Lake Como, September 1927 -- Quantum debate: The debate commences : Brussels, October 1927 ; An absolute wonder : Cambridge, Christmas 1927 ; The photon box : Brussels, October 1930 ; A bolt from the blue : Princeton, May 1935 ; The paradox of Schrödinger's cat : Oxford, August 1935 -- Interlude: The first war of physics : Christmas 1938-August 1945 -- Quantum fields: Shelter Island : Long Island, June 1947 ; Pictorial semi-vision thing : New York, January 1949 ; A beautiful idea : Princeton, February 1954 ; Some strangeness in the proportion : Rochester, August 1960 ; Three quarks for Muster Mark! : New York, March 1963 ; The 'God particle' : Cambridge, Massachusetts, Autumn 1967 -- Quantum particles: Deep inelastic scattering : Stanford, August 1968 ; Of charm and weak neutral currents : Harvard, February 1970 ; The magic of colour : Princeton/Harvard, April 1973 ; The November revolution : Long Island/Stanford, November 1974 ; Intermediate vector bosons : Geneva, January/June 1983 ; The standard model : Geneva, September 2003 -- Quantum reality: Hidden variable : Princeton, Spring 1951 ; Bertlmann's socks : Boston, September 1964 ; The Aspect experiments : Paris, September 1982 ; The quantum eraser : Baltimore, January 1999 ; Lab cats : Stony Brook/Delft, July 2000 ; The persistent illusion : Vienna, December 2006 -- Quantum cosmology: The wavefunction of the universe : Princeton, July 1966 ; Hawking radiation : Oxford, February 1974 ; The first superstring revolution : Aspen, August 1984 ; Quanta of space and time : Santa Barbara, February 1986 ; Crisis? What crisis? : Durham, Summer 1994 -- A quantum of solace? : Geneva, March 2010. (shrink)

We focus here on high-risk pediatric research with the prospect of direct benefit and point out some aspects that have raised significant debate. In particular, we call attention to disagreements related to two essential aspects of this type of research: (i) determining what constitutes a “prospect of direct benefit” in phase I trials that involve gene transfer technologies and (ii) assessing when in these trials the risk is justified by the anticipated benefit to the participant children. Although much of our (...) discussion is applicable to other types of high-risk pediatric trials, as an example of the dilemma this type of research poses we use pediatric trials that involve gene transfer technologies. We focus on clinical trials for late infantile neuronal ceroid lipofuscinosis (LINCL). Exploring the ethical implications of some of these disagreements might identify resources for determining how best to deal with the ethical concerns at stake in high-risk pediatric research. We thus offer some recommendations for responding to these concerns. (shrink)

In this paper I reconstruct Hegel’s famous critique of irony by drawing on present-day vice epistemology. I argue that the categories of contemporary theories of epistemic vices are sufficient to classify a type of irony as a vicious stance. Yet they fail to grasp the property in virtue of which irony deserves criticism. I show that, for Hegel, this feature is intellectual pride. In the remainder of the paper, I specify the axiological, metaphysical, and epistemological background assumptions which guide the (...) self-assessment of proud persons according to Hegel. Finally, I throw some light on the theoretical presuppositions of Hegel’s account of irony and pride. (shrink)

Two early drafts of the Essay have survived, one in the commonplace book Adversaria 1661, and the other in loose gatherings of leaves subsequently bound together into one volume by the Bodleian Library. Though both works were given titles by John Locke, they are now invariably known as Draft A and Draft B. Both manuscripts are in Locke's hand. Locke seems to have been doing further work on the Essay while in France. Draft C is very different from Drafts A (...) and B in one important respect. They are true drafts, written in Locke's own hand. The broad organization of Draft C is very similar to that of the published Essay, both (unlike Drafts A and B) being divided into books and chapters. The Abrégé covered all four books of the Essay, though Book Four was summarized briefly in a single paragraph. (shrink)

. New insights about a variety of epistemological topics including skepticism, peer disagreement, and the nature of knowledge emerge when we give the right sort of attention to our epistemic immaturity at the species level. This large-scale developmentalist concern illustrates a new way of doing epistemology, here called big epistemology.