The microbiota-gut-brain axis field is at an exciting stage, but the most recent developments in microbiota research still have to find their way into MGB studies. Here we outline the standards for microbiome data generation, the appropriate statistical techniques, and the covariates that should be included in MGB studies to optimize discovery and translation to clinical applications.

"The Symons Medal—one of Canada's most prestigious honours—recognizes an individual who has made an exceptional contribution to Canadian life. The 2020 Symons Medal was awarded to Mr. Bob Rae, P.C., C.C., O.Ont, Q.C. Mr. Rae is the 20th Medallist in this series, following a formidable line of recipients. Hon. Rae's lecture is Learning from The Past, Imagining the Future: Reflections from a Political Life. Throughout the address, published in a bilingual book format, he explores such themes as Canada's improbable origins (...) as a nation; post-war emergence onto the global stage; active membership within the United Nations; and the significance of the ever-evolving Canadian constitution—a "living tree document." Welcoming remarks were made by the Honourable Premier Dennis King, while the official response was delivered by the Honourable Roy Romanow, PC, OC, SOM, QC. Hon. Rae is the 2020 recipient in part for his many years of work on humanitarian issues, most recently the Rohingya Refugee crisis, as well as his time focusing on indigenous issues and his decades of public service and teaching. He has always been deeply involved in the political life of Canada—as MP, former premier of Ontario, and interim leader of the federal Liberal Party. The Symons Medal and Lecture Series is named in honour of Professor Thomas H.B. Symons, a long-time supporter of Confederation Centre and a Board Governor. Held each fall, the medal ceremony and its associated lecture offer a national platform for an eminent Canadian to discuss the nation’s current state, shared histories, and future prospects using themes related to their professional pursuits. The award is presented at Confederation Centre of the Arts—Canada’s living monument to Canadian Confederation—in honour of the meetings of the Fathers of Confederation, who first gathered at Province House National Historic Site in the fall of 1864."--. (shrink)

Rae Langton offers a new interpretation and defense of Kant's doctrine of things in themselves. Kant distinguishes things in themselves from phenomena, and in so doing he makes a metaphysical distinction between intrinsic and relational properties of substances. Langton argues that his claim that we have no knowledge of things in themselves is not idealism, but epistemic humility: we have no knowledge of the intrinsic properties of substances. This interpretation vindicates Kant's scientific realism, and shows his primary/secondary quality distinction to (...) be superior even to modern-day competitors. And it answers the famous charge that Kant's tale of things in themselves is one that makes itself untellable. (shrink)

Rae Langton here draws together her ground-breaking and contentious work on pornography and objectification. She shows how women come to be objectified -- made subordinate and treated as things -- and she argues for the controversial feminist conclusions that pornography subordinates and silences women, and women have rights against pornography.

The distinction at the heart of Kant's philosophy is a metaphysical distinction: things in themselves are substances, bearers of intrinsic properties; phenomena are relational properties of substances. Kant says that things as we know them are composed "entirely of relations", by which he means forces. Kant's claim that we have no knowledge of things in themselves is not idealism, but humility: we have no knowledge of the intrinsic properties of substances. Kant has an empiricist starting-point. Human beings are receptive creatures. (...) We must be affected by the things of which we come to have knowledge. Kant believes that humility follows from this fact of receptivity. Humility does follow from receptivity, once a further premise is supplied. Kant believes that relational properties, causal powers in particular, are not reducible to intrinsic properties, and that intrinsic properties are therefore causally inert. Receptivity implies that we can have knowledge only of what can affect us. Irreducibility implies, in Kant's view, that intrinsic properties cannot affect us. Humility follows from these. This interpretation finds support in a range of critical and pre-critical writings, but there is a special focus on an early anti-Leibnizian argument for irreducibility that has considerable philosophical merit. One advantage of this interpretation is that the following famous contradiction is dissolved: things in themselves exist, and are the causes of phenomena, and we have no knowledge of them as they are in themselves. Moreover Kant's scientific realism, surprising on an idealist interpretation, makes sense. It does not conflict with Kant's claim that he makes all the qualities secondary--he means that he makes them powers, or in Locke's terms, tertiary qualities. Kant's "primary"/secondary quality distinction is superior to widely accepted alternatives, and his application of the irreducibility argument to the primary qualities challenges some current orthodoxies. Kant's commitment to the unobservables of science is permitted by his understanding of receptivity: we can have knowledge of anything that can affect us. Kant's scientific realism, and his humility, thus have a common source. (shrink)

Gavin Rae shows that the problematic status of agency caused by the poststructuralist decentring of the subject is a central concern for poststructuralist thinkers. He shows how this plays out in the thinking of Deleuze, Derrida and Foucault, and find the best explanation of agency for the founded subject in the work of Castoriadis.

The Western philosophic tradition has tended to tie the question of action to that of freedom, with the relationship structured around the free will/determinism opposition. In contrast, I show that in Being and Nothingness, Sartre offers a stringent and radical critique of these approaches. I briefly outline the conceptual parameters of Sartre’s early ontology, before showing that he rejects the free will tradition because of its underlying conception of freedom and insistence that action is reflective and will-based. According to Sartre, (...) consciousness is not a sum of parts, with one aspect (will) guiding the rest. Consciousness is a differentiated whole, divided between reflective and pre-reflective levels. Will is tied to the reflective level of consciousness and so cannot be said to be foundational given that reflectivity depends upon pre-reflectivity. Instead, it is an expressive effect of consciousness’s spontaneous, pre-reflective, projection of itself towards a particular end and value. (shrink)

Something could be round even if it were the only thing in the universe, unaccompanied by anything distinct from itself. Jaegwon Kim once suggested that we define an intrinsic property as one that can belong to something unaccompanied. Wrong: unaccompaniment itself is not intrinsic, yet it can belong to something unaccompanied. But there is a better Kim-style definition. Say that P is independent of accompaniment iff four different cases are possible: something accompanied may have P or lack P, something unaccompanied (...) may have P or lack P. P is basic intrinsic iff (1) P and not-P are nondisjunctive and contingent, and (2) P is independent of accompaniment. Two things (actual or possible) are duplicates iff they have exactly the same basic intrinsic properties. P is intrinsic iff no two duplicates differ with respect to P. (shrink)

We defend the view of some feminist writers that the notion of silencing has to be taken seriously in discussions of free speech. We assume that what ought to be meant by ‘speech’, in the context ‘free speech’, is whatever it is that a correct justification of the right to free speech justifies one in protecting. And we argue that what one ought to mean includes illocution, in the sense of J.L. Austin.

Despite Jean-Paul Sartre and Cornelius Castoriadis placing the imagination centre stage in their respective conceptual theories, little work has been done to bring them into conversation on this issue or, indeed, any other. This is perhaps not surprising given Sartre’s early work on this topic has tended to be downplayed in favour of his affirmation of freedom, while Castoriadis not only denigrates Sartre’s thinking generally and his account of the imagination specifically but also posits their relationship as one of opposition. (...) In contrast, this article brings them into conversation on the question of the imagination to call into question Castoriadis assessment of their relation. To do so, I outline Sartre’s position in The Imaginary, showing that Castoriadis assessment of Sartre’s notion is based on a problematic, if common, misunderstanding of Sartre’s notion of nothingness and its relationship to creativity. Having overcome the opposition that Castoriadis affirms between their respective positions, I argue that, while there certainly are differences between their positions, there are also important points of agreement and overlap between them, especially regarding the constitutive role that the imagination plays for consciousness, and the relationships between the imagination and freedom and the imagination and creativity, that point to a shared and original approach. (shrink)

What is the point of language? If we begin with that abstract question, we may be tempted towards a high-minded answer: “People say things to get other people to come to know things that they didn't know before” (Stalnaker, 2002, 703). The point is truth, knowledge, communication. If we begin with a concrete question, “What has language to do with race?” we find a different point: to attack, spread hatred, create racial hierarchy. The mere practice of racial categorization is controversial: (...) are race terms natural or social kind terms? What does categorization do to the categorized? (Outlaw, 1990; Omi and Winant, 1994; Appiah, 1996; Andreason, 1998; Kitcher, 1999; Zack, 2002; Haslanger, 2008; Glasgow, 2009). But there is worse than mere categorization to contend with. (shrink)

If, as many suppose, pornography changes people, a question arises as to how.1 One answer to this question offers a grand and noble vision. Inspired by the idea that pornography is speech, and inspired by a certain liberal ideal about the point of speech in political life, some theorists say that pornography contributes to that liberal ideal: pornography, even at its most violent and misogynistic, and even at its most harmful, is political speech that aims to express certain views about (...) the good life, 2aims to persuade its consumers of a certain political point of view—and to some extent succeeds in persuading them. Ronald Dworkin suggests that the pornographer contributes to the ‘moral environment, by expressing his political or social convictions or tastes or prejudices informally’, that pornography ‘seeks to deliver’ a ‘message’ , that it reflects the ‘opinion’ that ‘women are submissive, or enjoy being dominated, or should be treated as if they did’, that it is comparable to speech ‘advocating that women occupy inferior roles’.3 Pornography on this view is political speech that aims to persuade its listeners of the truth of certain ideas about women, and of course ‘the government must leave to the people the evaluation of ideas’.4 Another answer offers a vision that is not grand and noble, but thoroughly reductive. Pornography is not politically persuasive speech, but speech that works by a process of psychological conditioning. This view seems common enough in the social science literature. Consider, for example, this description of an early experiment, from a time that pre-dates contemporary political debate. (shrink)

The effect of specificity of autobiographical memory (AM) retrieval on the affective impact of an emotional event was examined. In Study 1 (N = 90) the impact of a negative and positive experience was compared between student participants who habitually retrieve autobiographical memories (AMs) in a specific way and participants who generally retrieve less specific memories. In Study 2 (N = 48) the effect of an experimentally induced (specific vs. overgeneral) retrieval style on the impact of a negative experience was (...) studied in student participants who habitually retrieve less specific memories. Study 1 replicated the finding of Raes, Hermans, de Decker, Eelen, & Williams (Citation2003) that a negative event leads to less subjective distress in low‐specific participants as compared with high‐specific participants. However, both groups did not differ in their affective reaction to a positive event. Important, reduced memory specificity was associated with “repressive coping”, providing further evidence for the idea that reduced memory specificity is used as an avoidant or repressive‐defensive mechanism to regulate negative affect (CitationWilliams, 1996). In Study 2, participants who were induced to retrieve memories in an overgeneral way experienced more distress following a negative event as compared with participants who were induced to retrieve memories in a specific way. Results are discussed in the context of recent findings concerning AM specificity and emotion regulation (CitationPhilippot, Schaefer, & Herbette, 2003). Directions for further research are suggested. (shrink)

Several alleged counterexamples to the definition of ‘intrinsic’ proposed in Rae Langton and David Lewis, ‘Defining “Intrinsic”’, are unconvincing. Yet there are reasons for dissatisfaction, and room for improvement. One desirable change is to raise the standard of non-disjunctiveness, thereby putting less burden on contentious judgements of comparative naturalness. A second is to deal with spurious independence by throwing out just the disjunctive troublemakers, instead of throwing out disjunctive properties wholesale, and afterward reinstating those impeccably intrinsic disjunctive properties that are (...) not troublemakers. (The second of these changes makes the first more affordable.) A third, suggested by Brian Weatherson, would be to invoke the general principle that the intrinsic and the extrinsic characters of things are independent, rather than relying just on one special case of this principle; but it is none too obvious how to do this. (shrink)

Dan Marshall and Josh Parsons note, correctly. that the property of being either a cube or accompanied by a cube is incorrectly classified as intrinsic under the definition we have given unless it turns out to be disjunctive. Whether it is disjunctive, under the definition we gave, turns on certain judgements of the relative naturalness of properties. They doubt the judgements of relative naturalness that would classify their property as disjunctive. We disagree. They also suggest that the whole idea of (...) judging relative naturalness is a dubious business. We reply that, like them or not, such judgements cannot easily be avoided. (shrink)

Prince of Networks is the rst treatment of Bruno Latour speci cally as a philosopher. Part One covers four key works that display Latour’s underrated contributions to metaphysics: Irreductions, Science in Action, We Have Never Been Modern, and Pandora’s Hope. Harman contends that Latour is one of the central gures of contemporary philosophy, with a highly original ontology centred in four key concepts: actants, irreduction, translation, and alliance.

Kant argued that we have no knowledge of things in themselves, no knowledge of the intrinsic properties of things, a thesis that is not idealism but epistemic humility. David Lewis agrees (in 'Ramseyan Humility'), but for Ramseyan reasons rather than Kantian. I compare the doctrines of Ramseyan and Kantian humility, and argue that Lewis's contextualist strategy for rescuing knowledge from the sceptic (proposed elsewhere) should also rescue knowledge of things in themselves. The rescue would not be complete: for knowledge of (...) things in themselves would remain elusive. (shrink)

This is a paper about two philosophers who wrote to each other. One is famous; the other is not. It is about two practical standpoints, the strategic and the human, and what the famous philosopher said of them. And it is about friendship and deception, duty and despair. That is enough by way of preamble.

Although it is well-known that Hannah Arendt gives a privileged role to action, her comments on the relationship between action and will(ing) have caused much confusion in the literature: commentators are split on whether her analysis of willing in The Human Condition (from 1958) and the essay “What is Freedom?” (from 1960) contradict or are complemented by her later analysis in The Life of the Mind (from 1978). I defend the latter position, but in contrast to others who have affirmed (...) the same argument but focus on other themes to show it, I actually set out to show that Arendt offers a remarkably consistent analysis of the relationship between action and will(ing) throughout her work. To do so, I adopt a somewhat counterintuitive hermeneutical strategy by starting with her late analysis of will(ing) in The Life of the Mind (from 1978) where she most explicitly distinguishes between the historically dominant form of will(ing) of the liberium arbitrium and what I call natal-will(ing), before reading that distinction back into her earlier analyses of freedom in “What is Freedom?” (published in 1960), and action in The Human Condition (published in 1958). This hermeneutical strategy is underpinned by the claim that the distinction between two forms of will(ing) made explicit in The Life of the Mind is implicit to those earlier works. This shows that Arendt’s critique of will(ing) in her earlier works is a critique of the free will tradition, not willing per se, while her affirmation of action in those texts, implies the affirmation of the other form of willing, tied to natality and the power to begin anew, that she subsequently explicitly identifies in The Life of the Mind. (shrink)

School psychologists often break confidentiality if confronted with risky adolescent behavior. Members of the National Association of School Psychologists ( N = 78) responded to a survey containing a vignette describing an adolescent engaging in risky behaviors and rated the degree to which it is ethical to break confidentiality for behaviors of varying frequency, intensity, and duration. Respondents generally found it ethical to break confidentiality when risky adolescent behaviors became more dangerous or potentially harmful, although there was considerable variability between (...) respondents. Significant gender effects were found between male and female respondents for alcohol use, and a significant Form Type (i.e., male or female vignette) Frequency/Duration interaction was observed for antisocial behaviors. School psychologists could benefit from further training in ethical decision making because these ethical dilemmas are not always clear-cut. (shrink)

In ‘The Harm in Hate Speech’ Waldron’s most interesting and ground-breaking contribution lies in a distinctive epistemological role he assigns to hate speech legislation: it is necessary for assurance of justice, and thus for justice itself. He regards public social recognition of what is owed to citizens as a public good, contributing to basic dignity and social standing of citizens. His claim that hate speech in the public social environment damages assurance of justice has wider implications, I argue: for hate (...) speech conducted in private; for pornography; and indeed for any speech that thwarts knowledge of what justice requires. (shrink)

In this article, I argue for the notion of what I term ‘uncanny water’ as a conceptual tool for reading contemporary oceanic fictions. The uncanny’s affective capacity to destabilise epistemological and ontological certainties makes it a particularly potent literary tool for challenging the nature/culture binary. I argue that fictions which actively defamiliarise the ocean can be used to redress the anthropocentric privilege found in hitherto narratives of the oceanic that were predicated upon mastery and control, and that uncanny moments of (...) displacement and uncertainty can illuminate human/oceanic interconnections and foster a sense of responsibility and compassion towards the oceans. I identify resonances between the uncanny’s continuing referentiality and the notion that feminist transcorporeality interrelates the subject into networks of materiality which extend across time and space in unknowable ways. Both transcorporeality and the uncanny work against the conceit of the individual through the dissolution of boundaries, and, crucially, both require a suspension of assumptions of the self as whole, discrete and impermeable. To demonstrate this, I read the uncanny waters of contemporary fictions from the Northern Atlantic Littoral (Atlantic Canada and the westernmost parts of the UK). The littoral position of these spaces makes them ideally placed to negotiate the borders between habitable and unhabitable spaces, and the limitations of knowledge that run alongside this. I assert that iterations of uncanny water offer a transoceanic dialogue which shifts constructions of subjectivity away from national and terrestrial boundaries to one more akin to the fluid and relational dialectics of transcorporeality. (shrink)

The Kristeva–Lacan relationship has been a difficult one, with commentators tending to either collapse the former into the latter or insist on an absolute division wherein Kristeva emphasizes the m...

This chapter sets forth a general theory of gender stratification. While both biological and ideological variables are taken into account, the emphasis is structural: It is proposed that the major independent variable affecting sexual inequality is each sex's economic power, understood as relative control over the means of production and allocation of surplus. For women, relative economic power is seen as varying-and not always in the same direction-at a variety of micro- and macrolevels, ranging from the household to the state. (...) A series of propositions links the antecedents of women's relative economic power, the interrelationship between economic and other forms of power, and the forms of privilege and opportunity into which each gender can translate its relative power. (shrink)

This essay examines Carson’s The Trojan Women: A Comic, a 2021 translation of Euripides illustrated by Rosanna Bruno. Carson’s subtitle, through the intersection of classical and modern senses of “the comic” as a genre, demands that the reader ask of her book: What is the place of comedy in a comic about one of the bleakest plays in the Western canon? The comic elements of The Trojan Women reframe Euripides’ narrative and underscore, in a bitter irony, the disastrous impact on (...) the Greeks of the reconciliation of the gods Athena and Poseidon. (shrink)

Matter’s real essence is a ground for certain features of phenomena. Things in themselves are likewise a ground for certain features of phenomena. How do these claims relate? The former is a causal essentialism about physics, Stang argues; and the features so grounded are phenomenally nomically necessary. The latter involves a distinctive ontology of things in themselves, I argue; but the features so grounded are not noumenally nomically necessary. Stang’s version of Kant’s modal metaphysics is admirable, but does not go (...) far enough. Kant’s causal essentialism involves the essences of fundamental properties, as well as of matter. And things in themselves are grounds, because they are substances, the ‘substrate’ of phenomena. (shrink)

Those commentators who accept that Agamben offers an affirmative political project tend to hold that its realization depends upon pre-personal messianic or ontological alterations. I argue that there is another option based around the notion of individual agency that has received relatively little attention, but which clarifies whether or not Agamben holds that the transition is one that agents can participate in. By engaging with the texts “On Potentiality,” “Bartleby, or On Contingency,” and Opus Dei, I first show that he (...) develops a notion of potentiality that he claims not only underpins willing, but is also defined by an indeterminate contingency between action and non-action that undermines the binary opposition between willed action and non-action that sustains biopolitics. I then turn to the discussions of praxis, work, and poiesis in The Man without Content to determine whether Agamben thinks that other non-will-based forms of activity can contribute to the deactivation of biopolitics and, indeed,... (shrink)

Gavin Rae analyses the history of Western conceptions of evil, showing it to be remarkably complex, differentiated and contested. He traces the problem of evil from early and Medieval Christian philosophy to modern philosophy, German Idealism, post-structuralism and contemporary analytic philosophy and secularisation.

While Freud and Heidegger were antipathetic towards one another’s ideas, a number of commentators have argued that the Freud–Heidegger relation is actually quite complementary. This paper contributes to this position by engaging with the relationship through the mediation of their respective views on the ‘origins’ of sexuality; a topic that is implicit to Freudian psychoanalytic theory and which is often taken to be absent from Heidegger’s, with the consequence that it has been ignored when bringing them into conversation. Having shown (...) that in the 1928 lecture course The Metaphysical Foundations of Logic, Heidegger does in fact address the question of sexuality in relation to the neutrality of Dasein outlined in the previous year’s Being and Time, I bring Freud and Heidegger into conversation on the question of the ‘origins’ of sexuality to suggest that there is a strong affinity between the two on this issue, insofar as both argue against any form of sexual essentialism by depending upon a processual ontology and affirming an originary sexual indeterminateness, which in the case of Freud takes the form of an initial bisexuality and in the case of Heidegger an ontological sexual neutrality, before concluding that, while Freud’s initial bisexuality forecloses sexuality within a binary framework, Heidegger’s notion of an ontological sexual neutrality does not, and so goes furthest in laying the ground for a rethinking of sexuality in non-essentialist, non-binary terms. (shrink)

In this book, Gavin Rae analyses the foundations of political life by undertaking a critical comparative analysis of the political theologies of Carl Schmitt and Emmanuel Levinas. In so doing, Rae contributes to key debates in contemporary political philosophy, specifically those relating to the nature of, and the relationship between, the theological, the political, and the ethical, as well as those questioning the existence of ahistoric metaphysical, ontological, and epistemological foundations. While the theological is often associated with belief in a (...) fixed foundation such as God or the truth of a religion, Rae identifies another sense rooted in epistemology. On this understanding, the ontological limitations of human cognition mean that, ultimately, human truth is based in faith and so can never be certain. The argument developed suggests that Levinas’ conception of the political is grounded in theology in the sense of religion, particularly the revelations of Judaism. For this reason, Levinas claims that the political decision is based on how to implement a prior religiously-inspired norm: justice. Schmitt, in contrast, develops a conception of the political rooted in epistemic faith to claim that the political decision is normless. While sympathetic to Schmitt’s conception of theology and its relationship to the political, Rae concludes by arguing that the emphasis Levinas places on responsibility is crucial to understanding the implications of this. The continuing relevance of Schmitt’s and Levinas’ political theologies is that they teach us that, while the political decision is ultimately normless, we bear an infinite responsibility for the consequences of this normless decision. (shrink)