Confronted by contemporary neoliberal crisis, apparently rooted in economistic, or even nihilistic worldviews, the task for the [sociologist] is not simply to impose … critique from without, but to...

A crucially important part of the biosphere – the virosphere – is too often overlooked. Inclusion of the virosphere into the global picture of protein structure space reveals that 63 protein domain superfamilies in viruses do not have any structural and evolutionary relatives in modern cellular organisms. More than half of these have functions which are not virus‐specific and thus might be a source of new folds and functions for cellular life. The number of viruses on the planet exceeds that (...) of cells by an order of magnitude and viruses evolve up to six orders of magnitude faster. As a result, cellular species are subject to a constitutive ‘flow‐through’ of new viral genetic material. Due to this and the relaxed evolutionary constraints in viruses, the transfer of domains between host‐to‐virus could be a mechanism for accelerated protein evolution. The virosphere could be an engine for the genesis of protein structures, and may even have been so before the last universal common ancestor of cellular life. (shrink)

In this paper we make a proposal for reforming biomedical research that is aimed to align re-search more closely with the so-called fair-share principle according to which the proportions of global resources as-signed to different diseases should agree with the ratios of human suffering associated with those diseases.

This paper aims (a) to provide characterizations of realism and instrumentalism that are philosophically interesting and applicable to economics; and (b) to defend instrumentalism against realism as a methodological stance in economics. Starting point is the observation that ‘all models are false’, which, or so I argue, is difficult to square with the realist's aim of truth, even if the latter is understood as ‘partial’ or ‘approximate’. The three cheers in favour of instrumentalism are: (1) Once we have usefulness, truth (...) is redundant. (2) There is something disturbing about causal structure. (3) It's better to do what one can than to chase rainbows. (shrink)

I present an alternative account of causation in the biomedical and social sciences according to which the meaning of causal claims is given by their inferential relations to other claims. Specifically, I will argue that causal claims are inferentially related to certain evidential claims as well as claims about explanation, prediction, intervention and responsibility. I explain in some detail what it means for a claim to be inferentially related to another and finally derive some implication of the proposed account for (...) the epistemology, semantics and metaphysics of causation. (shrink)

Culture is a uniquely human property. Although precursors to cultural practices are found in other animals, these precursors differ in kind from the conditions of human culture that have emerged through evolutionary processes. In order to illuminate the mutual dependence of biological-genetic and cultural evolution, the author investigates technology and the use of tools, as well as the way these abilities are transmitted, in order to understand what properties and abilities separate human beings from animals.

Human cognitive performance has crucial significance for legal process, often creating the difference between fair and unfair imprisonment. Lawyers, judges, and jurors need to follow long and complex arguments. They need to understand technical language. Jurors need to remember what happens during a long trial. The demands imposed on jurors in particular are sizeable and the cognitive challenges are discussed in this chapter. Jurors are often subjected to both tremendous decision complexity and tremendous evidence complexity. Some of these problems could (...) be ameliorated if we can somehow enhance the cognitive capacities, including attention and memory, of various players in trials. There are multiple ways in which cognition can be improved either by external tools or by an increasing number of biomedical interventions that act directly on the brain. The article surveys a range of beneficial and detrimental effects that substances can have on cognition. (shrink)

There is a plurality of good reasons for action. An adequate theory of practical rationality has to be compatible with it even if it requires certain modifications of our everyday practices of reasoning. Usual theories of practical rationality do not pass this test. It is envisaged how to revise adequately our understanding of practical rationality.

Advances in brain–brain interface technologies raise the possibility that two or more individuals could directly link their minds, sharing thoughts, emotions, and sensory experiences. This paper explores conceptual and ethical issues posed by such mind-merging technologies in the context of clinical neuroethics. Using hypothetical examples along a spectrum from loosely connected pairs to fully merged minds, the authors sketch out a range of factors relevant to identifying the degree of a merger. They then consider potential new harms like loss of (...) identity, psychological domination, loss of mental privacy, and challenges for notions of autonomy and patient benefit when applied to merged minds. While radical technologies may seem to necessitate new ethical paradigms, the authors suggest the individual-focus underpinning clinical ethics can largely accommodate varying degrees of mind mergers so long as individual patient interests remain identifiable. However, advanced decisionmaking and directives may have limitations in addressing the dilemmas posed. Overall, mind-merging possibilities amplify existing challenges around loss of identity, relating to others, autonomy, privacy, and the delineation of patient interests. This paper lays the groundwork for developing resources to address the novel issues raised, while suggesting the technologies reveal continuity with current healthcare ethics tensions. (shrink)

The notion of objectivity in science has come under critique of feminist writers. The scientific ideal of a detached, neutral observer, who has no race, no gender, no cultural identity, no class, and views the world “from nowhere,” has been challenged, and patterns of domination explored. Feminists argue that objectivity is a tacit generalization from the subjectivity of a small, privileged social group “of educated, usually prosperous, white men.” Hence, it is a result of the denial of the subjectivity of (...) women and other marginalized people. The task which I set before myself is to inquire into the problem of objectivity in science and to explore the relationship between objectivity and subjectivity. I argue that, although the feminists’ critique of objectivity contributes to a greater awareness of the problem of objectivity in science and indeed subjectivity matters, their critique is ill founded. It is an example of one of many stereotypes and simplifications that we can find in today’s feminist thought. The affective engagement with the world, the approach that I propose, leads us to knowledge beyond objectivity. It is a prerequisite of knowing persons as persons and things as they are. (shrink)

The problem of individuality, physical and mental, is one which obviously has great interest for philosophy. The unity and continuity of the ordinary human consciousness—the “ ego,” the “personality—give us the concrete standard by which we ordinarily judge other systems which have tended towards individuation. A comparative and evolutionary study of biological data, however, will provide us with many facts which throw a new light on the problem. They are often puzzling, but must be taken into account.

Our ordinary conception of time has it that there are temporal particulars: not only do people do things, but there are particular doings by people; not only are we born, but the birth of each one of us was a particular event, and each of us will have our own particular death. Temporal particulars in this sense are individuated, fundamentally, by their temporal locations or relations, rather than by their intrinsic or qualitative characteristics. In this respect they are unrepeatable, not (...) just de facto, but as a matter of their very nature. However, there is a tradition in philosophy that seriously downplays this aspect of our thinking about time. According to this tradition, the fundamental unit of temporal representation is _tensed truth_; the notion of an unrepeatable particular, individuated by its temporal location, is at best an abstraction from a complex of tensed truths. The aims of this paper are, first, to argue that the representation of temporal particulars is deeply implicated in our ordinary conception of the past as fixed and unalterable; and, secondly, to argue that the theorist of tensed truth is able to provide only a pale imitation of this aspect of our thinking. I will then reflect on the consequences of this for debates about the metaphysics of tense. (shrink)

El objetivo del presente trabajo es identificar el uso político de la imagen al servicio del Estado y la función del régimen democrático al interior del sistema filosófico de Thomas Hobbes. Tal propósito se aborda en dos momentos: I. se propone un análisis iconográfico, con lo cual se destaca una lógica de la presencia/ausencia de la multitud como un cuerpo político (i.e. problema de la dispersión); II. se retoman las discusiones en torno a la función de la democracia, y se (...) expone el problema de la dispersión como el paso de la multitud disuelta al pueblo junto a la consolidación del cuerpo soberano (i.e. régimen democrático). Se concluye que el uso político de la imagen, descrita a partir de la distinción entre la adoración civil y la adoración divina, por parte del poder soberano, es una exhortación hobbesiana a la regulación del miedo (ciu bono del sostenimiento del poder soberano). En consecuencia, el gobierno de la imagen implica el problema del régimen democrático. (shrink)

Name der Zeitschrift: Zeitschrift für kritische Sozialtheorie und Philosophie Jahrgang: 5 Heft: 1 Seiten: 4-13.

An entertaining and thought-provoking look at the food on our plates, and what it can teach us about being human, from the author of The Pig That Want's to be Eaten.

You can't go through a graduate programme in other humanities subjects and be considered competent in those fields unless you've done some work on gender and race issues. Feminist work is mainstream. In philosophy that's just not true. You could go through a philosophy degree to this day and never have a class by a woman, never have to encounter anything having to do with feminism or gender or race.

Synaesthesia is a neurodevelopmental condition characterised by anomalous sensory perceptions and associated alterations in cognitive function. This chapter summarises what is known about the familial transmission of synaesthesia and its genetic underpinnings. Early familiality studies showed evidence for a strong genetic predisposition, a highly skewed female: male ratio, and an absence of male-to-male transmission. These patterns supported an early hypothesis of a single-gene X-linked dominant mode of inheritance with male lethality. Subsequent analyses in larger samples indicated that the mode of (...) inheritance was likely to be more complex, with both the strong female skew and absence of male-to-male transmission brought into question. We review in detail the first whole genome linkage scan for auditory-visual synaesthesia and a subsequent family linkage study on coloured sequence synaesthesia. Together these results suggest linkage to five chromosomes but give no support for linkage to the X-chromosome. We discuss candidate genes within these regions and potential implications for the aetiology of synaesthesia. We also discuss the implications of these pioneering genome scans for our understanding of synaesthesia and of how different synaesthetic phenotypes may arise from different genetic predispositions interacting with other genes and with the environment. (shrink)

En este trabajo nos proponemos poner de manifiesto un aspecto poco estudiado del Contra los griegos de Taciano ; nos referimos a la introducción del discurso historiográfico en la apologética cristiana. En cumplimiento de nuestro objetivo daremos cuenta, por una parte, del carácter idiosincrático de la producción de este apologista en el contexto de la defensa de la fe cristiana en el s. II y analizaremos, por otra, lo que de acuerdo con nuestra línea de investigación es lo más relevante (...) de su controvertido modus cogitandi: el rechazo de la Filosofía como via regia de acceso al Cristianismo para las gentes de alta cultura y la introducción del discurso historiográfico como garantía de veracidad. In this paper we propose to highlight a little studied aspect of the Discourse Against the Greeks of Taciano ; we refer to the introduction of historiographical discourse in Christian apologetics. In fulfillment of our objective we will give account, on the one hand, of the idiosyncratic character of the production of this apologist in the context of the defense of the Christian faith in the s. II and we will analyze, on the other hand, what according to our line of research is the most relevant of his controversial modus cogitandi: the rejection of Philosophy as a way of access to Christianity for people of high culture and the introduction of the historiographical discourse as a guarantee of truthfulness. (shrink)

In ‘Kant’s Changing Cosmopolitanism’ and Kant and Cosmopolitanism: The Philosophical Ideal of World Citizenship, Pauline Kleingeld argues that, in ‘Idea for a Universal History with a Cosmopolitan Intent,’ Kant meant for the Bund of states to be a coercive federation. Kleingeld admits that there is a disparity between this earlier coercive idea of the Bund and Kant’s talk of a voluntary congress in Toward Perpetual Peace and The Metaphysics of Morals. She explains this disparity by: appealing to a semantic ambiguity (...) in the term ‘Bund’; making claims about with which contemporary 18th century works Kant was acquainted; and ultimately attempting to draw a parallel between the unsocial sociability of individual people within a state and the unsocial sociability of individual states in a larger community of states. In this paper, I argue that while Kleingeld’s claims are superficially supported by the text, her claims depend on her apparent conflating of teleology and morality. (shrink)

Self-awareness is thought to be tied to processes of higher-order perspective taking including empathy. These abilities appear to be reserved for humans, great apes, and possibly, dolphins. Recent examinations reveal that both self-awareness and empathy may have origins in the right hemisphere. It is possible that, as in language, lateralization plays a key role in the development of higher-order perspective taking and self-awareness.

This article illustrates the practical usefulness of transdisciplinary work for practical theology by showing how input from an occupational therapist informed my understanding and interpretation of the story of Hannetjie, who had been sexually abused as a child. This forms part of a narrative practical theological research project into the spirituality of female adult survivors of childhood sexual abuse. Transdisciplinary work is useful to practical theologians, as it opens possibilities for learning about matters pastors have to face, but may not (...) have knowledge about. A short retelling of Hannetjie’s story is given to provide information about the context of the research. Next, the transdisciplinary process that was followed is mentioned, and the questions that the transdisciplinary team had to respond to are discussed. Following that, I focus more specifically on the occupational therapist’s answers, and the knowledge gained from her contribution, as an example of how a co-researcher from a divergent discipline can inform a theological study. In this case, knowledge was shared about sensory integration and how the brain processes traumatic stimuli, such as sexual abuse. Lastly, the interrelationship between Hannetjie’s body stories, mind stories and spirit stories is discussed to show how the learning received from occupational therapy affected my thinking about Hannetjie’s stories and the relationships between them. Thus, it is concluded that transdisciplinary work has great value for practical theology, especially in the pastor’s daily work with people who are struggling with difficult stories, because we cannot listen to people’s spirit stories in isolation. They are inextricably intertwined with all our stories about ourselves. (shrink)