Background: Parkinson’s disease is a neurodegenerative disease in which the progressive loss of dopaminergic neurons leads to initially sporadic and eventually widespread damage of the nervous system resulting in significant musculoskeletal and cognitive deterioration. Loss of motor function alongside increasing cognitive impairment is part of the natural disease progression. Gait is often considered an automatic activity; however, walking is the result of a delicate balance of multiple systems which maintain the body’s center of mass over an ever-changing base of support. (...) It is a complex motor behavior that requires components of attention and memory to prevent falls and injury. In addition, evidence points to the critical role of salient visual information to gait adaptability. There is a growing understanding that treatment for PD needs to address movement as it occurs naturally and walking needs to be practiced in more complex environments than traditional therapy has provided.MethodsIn this single-blinded randomized-controlled pilot study, an immersive treadmill training was piloted to determine feasibility and preliminary efficacy on gait and cognition in people with PD. Eighteen participants with Hoehn and Yahr stages I-III PD were randomized to either an intervention or a waitlist control group. Following baseline data collection, the intervention group trained for 30 min, three times/week for 4 weeks on a split belt treadmill combined with a first-person immersive video game targeting visuospatial skills and working memory. Assessment was repeated after 4 weeks of training for the experimental group and 1-month after baseline for the control group. Primary motor outcomes were captured with the APDM Opal sensors during 6 MWT, TUG, and TUG Cognitive. Secondary outcomes of cognition were measured with the Montreal Cognitive Assessment, Verbal Fluency and the Symbol Digit Modality Test. Within subject differences were calculated using the Wilcoxon Signed Ranked Test and between subject comparisons were analyzed using the Mann Whitney U-test.ResultsThis novel treadmill training program was well-tolerated with all participants in the intervention group completing 4 weeks of training three times a week without any adverse effects. After immersive cognitive motor training, the experimental group made clinically relevant improvements in gait speed and walking distance during the 6 MWT while members of the control group showed no change or decreased gait speed and walking distance over the 1-month trial. In addition, the experimental group demonstrated significant improvement for the TUG Cognitive and those changes were greater than the control group. The experimental group also improved scores on MoCA and SDMT cognitive outcome measures while the control group did not.ConclusionThe use of immersive gaming technology to engage specific areas of cognition related to gait is feasible in PD. The treadmill training program paired with a customized interactive video game improved walking velocity in addition to non-significant but consistent improvements in other gait measures and cognitive performance in participants with early to mid-stage PD. (shrink)

Transcranial magnetic stimulation (TMS) of the visual cortex can induce phosphenes as can non-diagnostic ultrasound, the latter while participants have closed their eyes during Stimulation. Here we sought to study potential alteration of a visual target (a white crosshair) due to application of diagnostic ultrasound to the visual cortex. We applied a randomized series of actual or sham diagnostic ultrasound to the visual cortex of healthy participants while they stared at a visual target, with the ultrasound device placed where TMS (...) elicited phosphenes. These participants observed percepts 7 out of 10 times, consisting of extra or extensions of lines relative to the original crosshair, and additional colors. Observation of a percept occurred an average of 53.7 +/- 2.6% of the time over the course of the experiment for these participants. In contrast, 7 out of 10 participants exposed to sham-only diagnostic ultrasound observed comparable percepts an average of 36.3 +/ 1.9% of the time, a statistically significant difference (p < 0.00001). Moreover, on average, participants exposed to a combination of sham and actual ultrasound reported a net increase of 47.9 percentage points in the likelihood that they would report a visual effect by the end of the experiment. Our experiment demonstrated that a random combination of sham-only and actual diagnostic ultrasound applied to the visual cortex of participants increased the likelihood that they would observe visual effects, but not the type of effects, with that likelihood increasing over the course of the experiment. From this we conclude that repeated exposures by diagnostic ultrasound made the visual cortex more responsive to stimulation of their visual cortex by the visual target. These observations, consistent with other’s observation of effects of diagnostic ultrasound stimulation of human motor cortex and amygdala, as well as the FDA approved nature of diagnostic ultrasound, may lead to increased study of diagnostic ultrasound applied to human brain. (shrink)

Seth Vannatta argues that there can be a fruitful synthesis of pragmatism and classical conservatism. In doing this, he focuses the methodological commitments of pragmatism and conservatism. However, I will demonstrate with a reading of Dewey’s Liberalism and Social Action that other commitments might prevent this synthesis—at least a synthesis between the thought of John Dewey and Edmund Burke. My conclusion is that pragmatism and conservativism might travel parallel to one another but that we have good reasons for keeping (...) some separation between the theories based upon their fundamental commitments. Deweyan pragmatism remains tied to democracy; conservatism remains tied to history. (shrink)

This book is a critical survey of and guidebook to the literature on biological functions. It ties in with current debates and developments, and at the same time, it looks back on the state of discourse in naturalized teleology prior to the 1970s. It also presents three significant new proposals. First, it describes the generalized selected effects theory, which is one version of the selected effects theory, maintaining that the function of a trait consists in the activity that led to (...) its differential persistence or reproduction in a population, and not merely its differential reproduction. Secondly, it advances “within-discipline pluralism” (as opposed to between-discipline pluralism) a new form of function pluralism, which emphasizes the coexistence of function concepts within diverse biological sub-disciplines. Lastly, it provides a critical assessment of recent alternatives to the selected effects theory of function, namely, the weak etiological theory and the systems-theoretic theory. The book argues that, to the extent that functions purport to offer causal explanations for the existence of a trait, there are no viable alternatives to the selected effects view. -/- The debate about biological functions is still as relevant and important to biology and philosophy as it ever was. Recent controversies surrounding the ENCODE Project Consortium in genetics, the nature of psychiatric classification, and the value of ecological restoration, all point to the continuing relevance to biology of philosophical discussion about the nature of functions. In philosophy, ongoing debates about the nature of biological information, intentionality, health and disease, mechanism, and even biological trait classification, are closely related to debates about biological functions. (shrink)

Frankfurt cases are supposed to provide us with counterexamples to the principle of alternative possibilities. Among the most well known responses to these cases is what John Fischer has dubbed the flicker of freedom strategy. Here we revisit a version of this strategy, which we refer to as the fine-grained response. Although a number of philosophers, including some who are otherwise unsympathetic to Frankfurt’s argument, have dismissed the fine grained response, we believe there is a good deal to be said (...) on its behalf. We argue, in particular, that reflection on certain cases involving omissions undermines the main objections to the response and also provides the groundwork for an argument in support of it. (shrink)

In the first book of the Prior Analytics, Aristotle sets out, for the first time in Greek philosophy, a logical system. It consists of a deductive system (I.4-22), meta-logical results (I.23-26), and a method for finding and giving deductions (I.27-29) that can apply in “any art or science whatsoever” (I.30). After this, Aristotle compares this method with Plato’s method of division, a procedure designed to find essences of natural kinds through systematic classification. This critical comparison in APr I.31 raises an (...) interpretive puzzle: how can Aristotle reasonably juxtapose two methods that differ so much in their aims and approach? What can be gained by doing so? Previous interpreters have failed to show how this comparison is legitimate or what important point Aristotle is making. The goal of this paper is to resolve the puzzle. In resolving this puzzle we not only learn more about the relationship be- tween division and the syllogistic in Aristotle. We will also learn something about the motivation for the syllogistic itself, by seeing the role that it plays in his philosophy of science. (shrink)

Evolutionary debunking arguments claim that evolution has influenced our moral faculties in such a way that, if moral realism is true, then we have no positive moral knowledge. I present several popular objections to the standard version of this argument, then give a new EDA that has clear advantages in responding to these objections. Whereas the Standard EDA argues that evolution has selected for many moral beliefs with certain contents, this New EDA claims that evolution has selected for one belief: (...) belief in the claim that categorical reasons exist. If moral realism is true, then this claim is entailed by all positive moral claims, and belief in it is defeated due to evolutionary influence. This entails that if realism is true, then we have no positive moral knowledge. While there may be objections against this New EDA, it is much stronger than the Standard EDA, and one realists ought to worry about. (shrink)

In contrast to scholars and signers in the nineteenth century, William Stokoe conceived of American Sign Language (ASL) as a unique linguistic tradition with roots in nineteenth-centurylangue des signes française, a conception that is apparent in his earliest scholarship on ASL. Stokoe thus contributed to the theoretical foundations upon which the field of sign language historical linguistics would later develop. This review focuses on the development of sign language historical linguistics since Stokoe, including the field's significant progress and the theoretical (...) and methodological problems that it still faces. The review examines the field's development through the lens of two related problems pertaining to how we understand sign language relationships and to our understanding of cognacy, as the term pertains to signs. It is suggested that the theoretical notions underlying these terms do not straightforwardly map onto the historical development of many sign languages. Recent approaches in sign language historical linguistics are highlighted and future directions for research are suggested to address the problems discussed in this review. (shrink)

An exceptional contribution to the teaching and study of Chinese thought, this anthology provides fifty-eight selections arranged chronologically in five main sections: Han Thought, Chinese Buddhism, Neo-Confucianism, Late Imperial Confucianism, and the early Twentieth Century. The editors have selected writings that have been influential, that are philosophically engaging, and that can be understood as elements of an ongoing dialogue, particularly on issues regarding ethical cultivation, human nature, virtue, government, and the underlying structure of the universe. Within those topics, issues of (...) contemporary interest, such as Chinese ideas about gender and the experiences of women, are brought to light. -/- Introductions to each main section provide an overview of the period, while brief headnotes to selections highlight key points. -/- The translations are the works of many distinguished scholars, and were chosen for their accuracy and accessibility, especially for students, general readers, and scholars who do not read Chinese. Special effort has been made to maintain consistency of key terms across translations. -/- Also included are a glossary, bibliography, index of names, and an index locorum of The Four Books. (shrink)

Research on the relationship between religious commitment and business ethics has produced widely varying results and made the impact of such commitment unclear. This study presents an empirical investigation based on a questionnaire survey of business managers and professionals in the United States yielding a database of 1234 respondents. Respondents evaluated the ethical acceptability of 16 business decisions. Findings varied with the way in which the religion variable was measured. Little relationship between religious commitment and ethical judgment was found when (...) responses were compared on the basis of broad faith categories – Catholic, Protestant, Jewish, other religions, and no religion. However, respondents who indicated that religious interests were of high or moderate importance to them demonstrated a higher level of ethical judgment (less accepting of unethical decisions) than others in their evaluations. Evangelical Christians also showed a higher level of ethical judgment. (shrink)

ABSTRACTIn this paper, I develop a truthmaker semantics for essence and use the semantics to investigate the explanatory role of essence.

There is a paucity of neuroaesthetic studies on prose fiction. This is in contrast to the very many impressive studies that have been conducted in recent times on the neuroaesthetics of sister arts such as painting, music and dance. Why might this be the case, what are its causes and, of greatest importance, how can it best be resolved? In this article, the pitfalls, parameters and prospects of a neuroaesthetics of prose fiction will be explored. The article itself is part (...) critical review, part methodological proposal and part opinion paper. Its aim is simple: to stimulate, excite and energize thinking in the discipline as to how prose fiction might be fully integrated in the canon of neuroaesthetics and to point to opportunities where neuroimaging studies on literary discourse processing might be conducted in collaborative work bringing humanists and scientists together. (shrink)

Facebook research has proliferated during recent years. However, since November 2017, Facebook has introduced a new limitation on the maximum amount of page posts retrievable through their Graph application programming interface, while there is limited documentation on how these posts are selected. This paper compares two datasets of the same Facebook page, a full dataset obtained before the introduction of the limitation and a partial dataset obtained after, and employs bootstrapping technique to assess the bias caused by the new limitation. (...) This paper demonstrates that posts with high user engagement, Photo posts and Video posts, are over-represented, while Link posts are under-represented. Top-term analysis reveals that there are significant differences in the most prominent terms between the full and partial dataset. This paper also reverse engineered the new application programming interface’s ranking algorithm to identify the features of a post that would affect its odds of being selected. Sentiment analysis reveals that there are significant differences in the sentiment word usage between the selected and non-selected posts. This paper has significant implications for the representativeness of research that use Facebook page data collected after the introduction of the limitation. (shrink)

The authors of these essays--including Judith Butler, Elizabeth Weed, and Rosi Braidotti--shed new light on the relationship of Irigaray to many of the philosophers she has "romanced," from Aristotle to Deleuze.

I examine how particular social arrangements and incentive structures encourage the honest reporting of experimental results and minimize fraudulent scientific work. In particular I investigate how epistemic communities can achieve this goal by promoting members to police the community. Using some basic tools from game theory, I explore a simple model in which scientists both conduct research and have the option of investigating the findings of their peers. I find that this system of peer policing can in many cases ensure (...) high levels of honesty. (shrink)

This paper raises an objection to two important arguments for reductive ethical naturalism. Reductive ethical naturalism is the view that ethical properties reduce to the properties countenanced by the natural and social sciences. The main arguments for reductionism in the literature hold that ethical properties reduce to natural properties by supervening on them, either because supervenience is alleged to guarantee identity via mutual entailment, or because non-reductive supervenience relations render the supervenient properties superfluous. After carefully characterizing naturalism and reductionism, we (...) will present, explain, and raise objections against each of the main reductionist arguments: that supervenience does not support the claim that ethical properties and their subvenient natural properties are mutually entailing; that reductive views undermine the claim that ethical properties yield resemblance; and that supervenience does not entail that non-descriptive ethical properties are superfluous in the most fundamental sense. (shrink)

Both advocates and critics of experimental philosophy often describe it in narrow terms as being the empirical study of people’s intuitions about philosophical cases. This conception corresponds with a narrow origin story for the field—it grew out of a dissatisfaction with the uncritical use of philosophers’ own intuitions as evidence for philosophical claims. In contrast, a growing number of experimental philosophers have explicitly embraced a broad conception of the sub-discipline, which treats it as simply the use of empirical methods to (...) inform philosophical problems. And this conception has a corresponding broad origin story—the field grew out of a recognition that philosophers often make empirical claims and that empirical claims call for empirical support. In this paper, I argue that the broad conception should be accepted, offering support for the broad origin story. (shrink)

Is there evidence of constitutionalism in classical Confucian political thought? In Sungmoon Kim's book on Confucian virtue politics, he argues that that Mencius (Mengzi, fourth century BCE) and Xunzi (third century BCE) are constitutionalists in the following sense: they expressed a commitment to creating durable institutions, one of whose primary aims is to constrain the exercise of legitimate political authority and facilitate good and proper uses of political authority. But for many political thinkers, the sort of constitutionalism that really matters (...) is the sort that entails a commitment to "constitutional remedies." Roughly, a constitutional remedy is some sanctioned means of enforcing the constraints or correcting political authorities who fail to abide by them. Moreover, it is often thought that the remedies should be entrenched – that is, widely recognized and regarded as beyond the legitimate power of the political authorities to change easily. Most decent political thinkers are constitutionalists in the the weak sense that they think there should be durable institutions that constrain abuses of power and facilitate good uses of power. Fewer go so far as to say that there should be entrenched checks and balances on that power, so that people's well-founded objections have something more than just rhetorical force against abuses of power. -/- In this paper, I examine whether Mencius and Xunzi would qualify as constitutionalists in the robust sense that presupposes entrenched remedies. I find that Mencius has some political commitments that might make him friendlier to aristocratic remedies than to democratic ones, but that his reluctance to divide political authority among non-ideal agents makes it difficult to know whether he would accept constitutional remedies of any sort. And my findings with respect to Xunzi are similar, but a modicum more hopeful: at best, Xunzi could be stretched to underwrite some aristocratic constitutional remedies, and he seems somewhat more open to dividing power among non-ideal agents. Neither Mencius nor Xunzi were robust constitutionalists, but it is historically and philosophically informative to ask how near they came to robust constitutionalism, and in which respects they fell short of it. -/- In the course of developing and justifying my interpretation, I call attention to two considerations in assessing an historical thinker's commitment to robust constitutionalism: first, whether the thinker invokes the threat of rebellion as a way of countenancing it or merely as a descriptive claim about likely consequences of bad governance; second, whether non-ideal political agents are empowered to check abuses of power. Only when the thinker actually countenances rebellion and allows that non-ideal political agents can check abuses can the thinker be plausibly described as a robust constitutionalist. (shrink)

Dedicated to the humanisticissimus and/or humanisticissima Editoreality of Critical Inquiry, an enterprise that is doing all possible to restore for Criticism its rightful home, namely: a state of perpetual Crisis. How now?You say"The manwalks down the street." Then tell me howyour wordsmake sense. Kenneth Burke's contributions to Critical Inquiry are "In Response to Booth: Dancing with Tears in my Eyes" , " Post-Poesque Derivation of a Terministic Cluster" , " Motion/ Action" ,and "Methodological Repression and/or Strategies of Containment".

Nietzsche appears to adopt a radical Kantian view of objects called constructivism, which holds that the existence of all objects depends essentially on our practices. This essay provides a new reconstruction of Nietzsche's argument for constructivism and responds to five pressing objections to reading Nietzsche as a constructivist that have not been addressed by commentators defending constructivist interpretations of Nietzsche.

I maintain that Hegel’s reading of the Antigone underestimates the power of the negativity to which Antigone’s action is dedicated. I argue that the negativity of death and the sacred cannot, contrary to Hegel, to be sublated and thus incorporated into the progression of Spirit. Bataille’s treatment of the sacred better characterizes the unworldly force and the otherness with which Antigone and Creon are confronted when their actions bring the divine and the human into conflict. Antigone’s obedience to what she (...) understands to be her divine obligation is a devotion to a negativity which exceeds and subverts all dialectical comprehension. Although her action brings the divine and the human political sphere into a moment of identity, allowing for the sublation of the ethical world, Antigone’s action is a transgression in Bataille’s sense of the term, and it points toward the limits of reason. The Antigone narrative thus exceeds Hegel’s use of it and is ultimately more consistent with Bataille’s understanding of the sacred. (shrink)

The existence of phenomenally conscious mental states is often taken to be obvious from first-person experience. Sytsma and Machery (2010) argued that if that is the case, then laypeople should classify mental states in the same way that philosophers typically do, treating states like seeing red and feeling pain similarly. We then presented evidence that they do not. This finding is interesting in its own right, however, outside of any implications for the philosophical debates concerning phenomenal consciousness. As such, we (...) attempted to explain our finding, presenting evidence that lay mental state ascriptions depend on valence judgments (that the mental states have a hedonic value for the subject). In this paper, I present new evidence that suggests against this valence account. I then provide evidence for a new explanation based on previous findings that laypeople tend to view both colors and pains as mind-independent qualitiesof objects outside the mind/brain. (shrink)

In Memories and Portraits, H. G. Callaway presents us with the memoir of a philosopher. I will, as readers of this review will hardly find surprising, be reviewing this book with two foci. First, I will address the merits of the work itself and, second, with an eye toward our shared interests in John Dewey, other pragmatists, and how the work incorporates or neglects pragmatism’s contributions to the themes Callaway discusses. However, in many ways this second task is auxiliary. Callaway (...) does not present us with a systematic text in philosophy, but rather a text that is a memoir about the author as much as it is about a philosopher, specifically, how the philosopher’s experiences have demonstrated the importance.. (shrink)

Logic for Dewey is a normative inquiry into the nature of inquiry itself. Goodman’s grue example is assessed in light of Dewey's vocabulary for logic as presented in his 1938 Logic.

Our actions have causes, some of which are beyond our control. Of that there can be no serious doubt. Some worry that this fact undermines the commonsense view that we perform free actions for which we are morally responsible. My aim in this article is to show that such worries are unfounded and, consequently, that pure non-causal theories of free action, according to which free actions must be entirely uncaused, are false. My argument for this conclusion doesn’t presuppose the cogency (...) of existing objections to non-causal theories of free agency. (shrink)

In this chapter the author defends the view that the major variants of Confucian ethics qualify as virtue ethics in the respects that matter most, which concern the focus, investigative priority, and explanatory priority of virtue over right action. The chapter also provides short summaries of the central Confucian virtues and then explains how different Confucians have understood the relationship between these and what some regard as the chief or most comprehensive virtue, ren (humaneness or benevolence). Finally, it explicates what (...) most Confucians take to be a requirement of all virtues, which the author calls “wholeheartedness,” and concludes by highlighting some neglected implications of the wholeheartedness requirement for ethics more generally. These include reasons for linking conceptions of virtue and human nature, for thinking that good character necessitates that individuals change how things seem to them, and for endorsing automatic as opposed to intensively deliberative judgments and decisions. (shrink)

New Visions of the Zhuangzi edited by Livia Kohn presents thirteen different essays on the Zhuangzi that will appeal to readers from any number of different backgrounds. The eclecticism of these essays, ranging in content from neuroscience to fashion shows, highlights the ever-increasing scope and relevance of ancient Chinese works like the Zhuangzi to contemporary life and thought. Also, the enterprising move of some essays away from a traditional schools-based approach also serves as an inspiration for future scholarly work. The (...) essays will be discussed in this review by grouping several according to overlapping themes, leaving the more stand-alone contributions to be addressed last.First of all, the cripple... (shrink)

An emerging topic in robot design and scholarly research is socially assistive robots for senior citizens. Compared to robots in other sectors, SARs can augment their assistive-utilitarian functions by offering social, emotional, and cognitive support to seniors. This study draws upon interviews with 45 senior citizens to understand this group’s expectations for human-robot interactions and their anticipated needs for robots. Our grounded theory analysis suggests that senior citizens expect robots to meet three types of needs: physical, informational, and interactional. Furthermore, (...) they seek assurances that they will have complete control over interactions with robots. Findings show that seniors’ mental models about robots are shaped by their recent experiences with advanced communications technologies and mediated representations of robots in popular culture. Findings are discussed in light of practical design considerations and two theoretical perspectives. (shrink)