_Interprets Kant's conception of enlightenment within the broader philosophical project of his critique of reason._.

This paper examines the relevance and importance of the large number of examples which Aristotle uses in his "Prior Analytics." In the first part of the paper three preliminary issues are raised: First, it investigates what counts as an example in Aristotle's syllogistic, and especially whether only examples expressed in concrete terms should be considered as examples or maybe also propositions and arguments with letters of the alphabet. The second issue concerns the kinds of examples Aristotle actually uses from everyday (...) life as well as from various scientific and philosophical forms of discourse; among these, it seems that biological examples, rather than mathematical ones, have a predominant place. Finally, I discuss what Aristotle himself has to say about the use of examples, and in particular about the similarity between the use of an example and the use of induction. The second part of the paper focusses on the functions of Aristotle's logical examples. It is of course obvious that some of the examples in the Prior Analytics are used to illustrate, and thus to clarify, a definition, a logical rule, a type of argument. However, I think that Aristotle's logical examples have another function, which is philosophically more interesting, namely as integral parts of the procedure of proving something. To support this claim, I analyse three passages from the "Prior Analytics" in which examples are used either in order to prove that something is not the case, i.e. as counter-examples, or in order to prove positively that it is possible for something to be the case. At the end, I argue that for such uses of examples Aristotle uses the notion of 'ekthesis', which seems to have a wider sense than usually suggested; that is to say, it is used to refer to any proof by means of an example, and not only for the procedure which Aristotle uses to reduce imperfect to perfect syllogisms. (shrink)

Hutto and Satne, Philosophia propose to redefine the problem of naturalizing semantic content as searching for the origin of content instead of attempting to reduce it to some natural phenomenon. The search is to proceed within the framework of Relaxed Naturalism and under the banner of teleosemiotics which places Ur-intentionality at the source of content. We support the proposed redefinition of the problem but object to the proposed solution. In particular, we call for adherence to Strict Naturalism and replace teleosemiotics (...) with autopoietic theory of living beings. Our argument for these adjustments stems from our analysis of the flagship properties of Ur-intentionality: specificity and directedness. We attempt to show that the first property is not unique to living systems and therefore poses a problem of where to place a demarcation line for the origin of content. We then argue that the second property is a feature ascribed to living systems, not their intrinsic part and therefore does not form a good foundation for the game of naturalizing content. In conclusion we suggest that autopoietic theory can not only provide a competitive explanation of the basic responding of pre-contentful organisms but also clarify why Ur-intentionality is attributed to them in such an intuitive manner. (shrink)

Regulations implemented by World Athletics (WA) require female athletes with differences of sexual development to suppress their blood testosterone levels in order to participate in certain women’s sporting competitions. These regulations have been justified by reference to fairness. In this paper, we reconstruct WA’s understanding of fairness, which requires a “level playing field” where no athlete should have a significant performance advantage based on factors other than talent, dedication, and hard work over an average athlete in their category. We demonstrate (...) that by placing regulations only on testosterone levels, while ignoring physical as well as socioeconomic advantages, WA consistently fails to meet its own definition of fairness. We then discuss several ways in which this definition could be met. Our analysis shows that a categorical system, in which athletes are divided into categories based on properties leading to significant performance advantages, is best suited for meeting WA’s definition of fairness. (shrink)

Phenotypic plasticity is a crucial feature of aggressive cancer, providing the means for cancer progression. Stochastic changes in tumor cell transcriptional programs increase the chances of survival under any condition. I hypothesize that unstable chromatin permits stochastic transitions between transcriptional programs in aggressive cancers and supports non‐genetic heterogeneity of tumor cells as a basis for their adaptability. I present a mechanistic model for unstable chromatin which includes destabilized nucleosomes, mobile chromatin fibers and random enhancer‐promoter contacts, resulting in stochastic transcription. I (...) suggest potential markers for “unsettled” chromatin in tumors associated with poor prognosis. Although many of the characteristics of unstable chromatin have been described, they were mostly used to explain changes in the transcription of individual genes. I discuss approaches to evaluate the role of unstable chromatin in non‐genetic tumor cell heterogeneity and suggest using the degree of chromatin instability and transcriptional noise in tumor cells to predict cancer aggressiveness. (shrink)

In this essay, I propose that DNA‐binding anti‐cancer drugs work more via chromatin disruption than DNA damage. Success of long‐awaited drugs targeting cancer‐specific drivers is limited by the heterogeneity of tumors. Therefore, chemotherapy acting via universal targets (e.g., DNA) is still the mainstream treatment for cancer. Nevertheless, the problem with targeting DNA is insufficient efficacy due to high toxicity. I propose that this problem stems from the presumption that DNA damage is critical for the anti‐cancer activity of these drugs. DNA (...) in cells exists as chromatin, and many DNA‐targeting drugs alter chromatin structure by destabilizing nucleosomes and inducing histone eviction from chromatin. This effect has been largely ignored because DNA damage is seen as the major reason for anti‐cancer activity. I discuss how DNA‐binding molecules destabilize chromatin, why this effect is more toxic to tumoral than normal cells, and why cells die as a result of chromatin destabilization. (shrink)

Thought experiments being central to contemporary philosophy and science, the following questions were asked in recent literature. What is their definition? Are they heuristic devices, arguments, paradoxes? Are they comparable to real experiments? Do intuition and conceivability intervene? Equally imaginative thought experiments are found in ancient, medieval, and Renaissance texts. Paying attention to prime historical examples of thought experiments, we show that historical perspectives help answer these general questions.

Katerina Deligiorgi offers a contemporary defence of autonomy which is Kantian but engages closely with recent arguments about agency, morality, and practical reasoning.

In his Foundations of a General Theory of Manifolds, Georg Cantor praised Bernard Bolzano as a clear defender of actual infinity who had the courage to work with infinite numbers. At the same time, he sharply criticized the way Bolzano dealt with them. Cantor’s concept was based on the existence of a one-to-one correspondence, while Bolzano insisted on Euclid’s Axiom of the whole being greater than a part. Cantor’s set theory has eventually prevailed, and became a formal basis of contemporary (...) mathematics, while Bolzano’s approach is generally considered a step in the wrong direction. In the present paper, we demonstrate that a fragment of Bolzano’s theory of infinite quantities retaining the part-whole principle can be extended to a consistent mathematical structure. It can be interpreted in several possible ways. We obtain either a linearly ordered ring of finite and infinitely great quantities, or a partially ordered ring containing infinitely small, finite and infinitely great quantities. These structures can be used as a basis of the infinitesimal calculus similarly as in non-standard analysis, whether in its full version employing ultrafilters due to Abraham Robinson, or in the recent “cheap version” avoiding ultrafilters due to Terence Tao. (shrink)

The article explores examples of theoretical endeavor to think the political in “accordance with the Real” that can be found in the works of François Laruelle, Alain Badiou and Slavoj Žižek. The task this article sets for itself is to establish an insight into – or rather, arrive to a certain vision and knowledge of – the possibilities of interrogating the modes of participation of the Real in the production of a Political Truth. I will claim the latter is not (...) the product of Discourse exclusively, but of the inter-action between the Discursive and the Real. In the deployment of this argument I resort to the epistemic posture of thought proposed by François Laruelle’s non-philosophy as "thinking in correlation with the Real." It is a stance of theorizing which is unilateral, non-thetic and does not attempt to reflect or mirror the Real. It merely correlates with it by way of acknowledging it to be the decisive instance of legitimization of the produced truth. (shrink)

Ethnic diversity and cultural heterogeneity are a reality for the city of Skopje, the capital of North Macedonia. The changing ethnic demography and redressed power-balance between majority and non-majority groups on local level have spurred a turbulent conflict – that of governance of diversity in public space. This paper aims to understand citizens’ views on how language, ethnicity, religion and collective cultural symbols are legitimised through the political, social and symbolic value of public spaces in their neighbourhoods. The results indicate (...) that the political value of public spaces to stimulate contact, deliberation and debate among citizens on issues of their concern is undermined. Public spaces in Skopje are not planned and managed through a wide forum of citizen engagement. The colliding ethnonationalism and symbolic power struggle between the major ethnic groups result in co-ethnic preferences in socialisation and selection of public spaces. The concept of “the appropriate citizen” constructed through the symbolic meaning of public spaces perpetuates ethnonational rhetoric and supports expressions of citizenship that are limited to the nation-state and ethnic identification. In opposition to contact theory, this research indicates that self-segregation of ethnic groups can be prevalent in multi-ethnic neighbourhoods. This should make us think of the context where the contact is established and not only of the content of the interaction. (shrink)

Our philosophical moral vocabulary expresses a predilection for depth; we customarily probe feelings, intentions, reasons for action. Friedrich Schiller's concept of grace offers an alternative: moral guidance is best sought in what we train ourselves to set aside, facial expression, sound of voice, movement. This surprising proposal merits our attention and speaks to some of our current concerns.

(2017) 'Interest and Agency', in Gabriel, Markus and Rasmussen, Anders Moe (eds.) German Idealism Today. De Guyter Verlag. -/- Abstract: Undeterred by Kant’s cautionary advice, contemporary defenders of free will advance substantive metaphysical theses in support of their views. This is perhaps unsurprising given the mixed reception of Kant’s solution of the conflict between freedom and natural necessity, which is supposed to vindicate reason’s withdrawal from speculation. Kant argues that neither libertarians nor determinists can win, because they deal with concepts (...) of unrestricted scope, and proposes instead to regiment the reference conditions of each concept and to specify the domain, ‘world’, proper to each. However, the precise character of this solution, its conceptual and metaphysical commitments, continues to be a matter of controversy among Kant scholars. In particular, there is ever-renewed concern about the incipient dualism of the position. Although I will be examining some of this material, my primary aim in this paper is not to make a contribution to the interpretative debate about the antinomy. Rather, I want to draw on two lessons from Kant’s treatment of the antinomy to argue for the importance of a certain way of putting the problem of human freedom. (shrink)

Abstract In this paper I set the debate between Kant and Schiller in terms of the role that an ideal of life can play within an autonomist ethic. I begin by examining the critical role Schiller gives to emotions in tackling specific motivational concerns in Kant's ethics. In the Kantian response I offer to these criticisms, I emphasise the role of metaphysics for a proper understanding of Kant's position whilst allowing that with respect to moral psychology, Kant and Schiller are (...) in agreement about the importance of emotions in our moral lives. I conclude by returning to the themes broached in the introduction to consider the extent to which the teleological concerns that motivate Schiller can be addressed within Kant's autonomist ethics. (shrink)

The scope of the paper is to present the concept of the radical dyad of the “non-human,” in an attempt to think radical humanity in terms of Marxian materialism, which is the product of approaching Marx’s writings on “the real” and “the physical” by way of François Laruelle’s non-philosophical method. Unlike posthumanism, inspired by critical theory and the method of poststructuralism, the theory of the non-human, as a radical dyad of technology in the generic sense of the word (ranging from (...) the techné of speaking a natural language to AI technology) and the organic understood as physicality, does away with anthropocentrism. Moreover, it does away with any anthropomorphology of thought, that is, it does away with any theorizing or philosophy that is centered on the notion of (human) subjectivity or, to borrow a Laruellian term, any “posture of thought” that is molded according to the structure of subjectivity centered thinking. (shrink)

Cognitive and emotional processes are now known to be intertwined and thus the limbic system that underlies emotions is important for human brain evolution, including the evolution of circuits supporting language. The neural substrates of limbic functions, like motivation, attention, inhibition, evaluation, detection of emotional stimuli and others have changed over time. Even though no new, added structures are present in the human brain compared to nonhuman primates, evolution tweaks existing structural systems with possible functional implications. Empirical comparative neuroanatomical evidence (...) is presented here in support of such changes in the limbic system, including the amygdala and the orbitofrontal cortex. Given their possible functional significance, these alterations may further enable and enhance human interest and motivation to communicate beyond what is seen in other primates living in complex social groups. The argument here is that even though emotion processing is likely needed for increased social complexity independent of language, the reason why humans want to talk may be related in part to the enhancement of socioemotional processes resulting from the reorganization and rewiring of underlying neural systems some of which are interconnected to the language areas. Neurodevelopmental disorders in humans affecting both language and sociability fuel such arguments. (shrink)

The focus of this paper is on E. H. Gombrich's claim that pictorial perception is a case of illusion. My aim is to point out that, on the one hand, the interpretation of this claim that is widely accepted in pictorial theory is not supported by Gombrich's analysis of pictorial perception; and, on the other hand, that the interpretation of the claim that I see as more compatible with Gombrich's analysis is not consistent with relevant facts about our relation to (...) pictures. However, I will argue, Gombrich's elaboration of the claim of illusion is significant to the extent that it highlights important aspects of the system of pictorial representation. (shrink)

A specific type of collaboration has become prevalent in contemporary art: in this type of collaboration—henceforth, commissioning—an artist assigns the production of the work of art to skilled craftsmen or unskilled workers, directing their labor through instructions or blueprints. Commissioning has been accepted by the art world as a legitimate mode of artistic production—legitimate in the sense that it does not undermine the authenticity of the work as a creation of the artist, even if she has not laid a hand (...) for its production. Moreover, commissioning seems to be regarded as irrelevant to the nature of the work of art—specifically, to its artistic properties—and, thus, to its proper appreciation, as is.. (shrink)

Following François Laruelle's nonstandard philosophy and the work of Judith Butler, Drucilla Cornell, Luce Irigaray, and Rosi Braidotti, Katerina Kolozova reclaims the relevance of categories traditionally rendered "unthinkable" by postmodern feminist philosophies, such as "the real," "the one," "the limit," and "finality," thus critically repositioning poststructuralist feminist philosophy and gender/queer studies. Poststructuralist (feminist) theory sees the subject as a purely linguistic category, as _always alread_y multiple, as _always already_ nonfixed and fluctuating, as limitless discursivity, and as constitutively detached from (...) the instance of the real. This reconceptualization is based on the exclusion of and dichotomous opposition to notions of the real, the one (unity and continuity), and the stable. The non-philosophical reading of postructuralist philosophy engenders new forms of universalisms for global debate and action, expressed in a language the world can understand. It also liberates theory from ideological paralysis, recasting the real as an immediately experienced human condition determined by gender, race, and social and economic circumstance. (shrink)

There is no single ancient Greek word in the surviving fragments and testimonies of Hellenistic philosophy that is directly translatable by the term ‘intuition’. But if we are in search of intuitions in the context of Hellenistic epistemology, it could be said that both the Stoics and the sceptics made use of them in their philosophical debates; for intuitions seem to be closely connected with the formation of conceptions, which were abundantly used by all Hellenistic philosophers. It is important to (...) understand, though, that the Stoics’ and the sceptics’ attitude towards the epistemic status of intuitions would greatly differ: The Stoics would explain intuitions by invoking a rational capacity of human beings, which based on experience would put them in touch with the reality of things, so that their intuitions could be thought of as somehow rationally admissible. The sceptics, on the other hand, would suggest that intuitions guide our everyday life merely on the basis of our previous experiences, and thus their intuitions could be regarded as empirically justified, although they would not guarantee any access to how things actually are. (shrink)

The articles contained in this collection look at the displacements, upheavals and dislocations in the traditional definition of obligation as experienced in the 18th and early 19th centuries from the perspective of the humanities and cultural studies. The works in this volume not only focus on Kantian moral philosophy, as the pinnacle of a specific modern development, but also examine the diverse other concepts of obligation and how they were formulated through literature, aesthetics, politics and pedagogy.

Abstract:In Book X of the Republic, Plato develops a structured criticism of the images of painting in order to denigrate, by means of analogy, the cognitive value of poetry. Yet Plato persistently employs verbal images at points of utmost importance with regard to his philosophical aims. In the face of Plato’s critique of the image, his methodic use of images can seem paradoxical: critique and method point in opposing directions with regard to the cognitive value of the image. The aim (...) of this article is to promote a moderate cognitivist stance on Plato’s use of verbal images, using to this end the understanding that contemporary philosophy affords us. Operating through the lens of the metaphor of “philosophical paintings,” which they deem as apt and instructive, the authors (a) trace in Book X’s critique of painting the specific properties of the verbal images that can allow a cognitive function in the context of philosophical instruction, (b) examine and refute a pertinent objection to this moderate cognitivist stance, and (c) argue for the overall consistency between the critique of Book X and Plato’s use of verbal images, drawing on evidence in Plato’s practice that he acknowledges the risk of the image’s allure and is proactive in relation to this risk. (shrink)

This paper, located in the traditions of Interactional Sociolinguistics (Gumperz 1982) and Social Constructionism (Berger and Luckmann 1966), explores code-switching and identity practices amongst British-born Greek-Cypriots. The speakers, members of a Greek-Cypriot youth organization, are fluent in English and (with varying levels of fluency) speak the Greek-Cypriot Dialect. Qualitative analyses of recordings of natural speech during youth community meetings and a social event show how a new ‘third space’ becomes reified through code-switching practices. By skillfully manipulating languages and styles, speakers (...) draw on Greek-Cypriot cultural resources to accomplish two inter-related things. First, by displaying knowledge of familiar Greek-Cypriot cultural frames, they establish themselves as different from mainstream British society and establish solidarity as an in-group. Secondly, by using these frames in non-serious contexts, and at times mocking cultural attitudes and stereotypes, they challenge and re-appropriate their inherited Greek-Cypriot identity, thereby constructing the identity of British-born Greek-Cypriot youth. (shrink)

Physics is the most fundamental of the sciences and its main purpose is to explain how the world works on the smallest as well as the largest scales. This book outlines the most important discoveries and technical development in the field of physics during the past two decades. The reader will learn the basics of the major theories that form the backbone of the current understanding of the universe through descriptions of the latest findings in particle physics, quantum optics, structure (...) of matter or astrophysics. The book also explains how devices such as lasers or particle accelerators work. (shrink)

The opposition between the climactic thought of René Descartes and that of Blaise Pascal, although not very explicitly expressed at the time, is considered to be some kind of dispute between “reason and the heart.” An attempt at the relativization of these compartmentalizing poles brings the author of the study to a starting point that is common to Descartes’ Meditations on First Philosophy and Pascal’s Pensées (Thoughts): the act of skepticism and radical doubt. Despite the differences in their skeptical pathways (...) and their goals, the roots of the “systems” of thought of both philosophers grow from this act. The paper attempts to outline how the role of doubt can shape the problem of human knowledge, both on a general level and on the level of the highest, concrete knowledge of Divine Existence. (shrink)

The human is materially determined by that “irrational” hybrid of the physical and machine resulting in no more and no less sense than the “pure body” (if such thing is possible beyond mere postulation) is endowed with. The “rational” part of it or the “agency of making sense” remains outside the materiality of either the body or the machine—it is the automaton of signification or language. The automaton of capital and philosophy is individually substantiated as “subjectivity,” and more specifically that (...) of the split capitalist self. The hybrid consisted of the physical (natural and machinic), on the one hand, and of the subject of signification, on the other hand, is the monstrosity that ultimately escapes sense: it is inhuman (Haraway) or non-human (Laruelle). It is that inhuman inanity that is neither subject nor merely body nor just a machine, the non-human. Similarly to Donna Haraway's claim about the radical constructedness of the human as cyborg (Haraway, 1991: 149–181), Marx argued that sociality, which includes both economic production and the so-called social reproduction (via the means of production), on the one hand and physicality on the other hand constitute the species-being of humanity. The human is radically constructed, yet, in the last instance, determined by the physical, argue both Haraway and Marx. (shrink)

Moral judgements usually concern the moral responsibility of an acting person. Someone is considered praiseworthy or blameworthy for an action based on whether this action is according to or against moral norms. According to a Kantian account, the essential issue is the motivation of the acting person since this is a measure for being a moral cause of the action i.e. for intending it. Only moral causation allows the moral imputation of the action to the acting person. And moral motivation (...) always implies the use of practical reason, as the capacity of acting in accordance to rules, while there are two kinds of rules (categorical and hypothetical). To give priority to one of these would lead to moral merit or to moral guilt. The latter considers the acting person as treating himself or others merely as a means instead to respecting himself or others as persons i.e. as individuals able to act according to their own aims and to be responsible for that. We find such an account in Johann Christoph Hoffbauer’s interpretation of Kant’s theory of free will. While Kant is occasionally accused of inconsistency in claiming evil actions are real and imputable while claiming only good actions are free (and therefore imputable), Hoffbauer offers a consistent version of Kant’s theory of free will. In this paper, I analyze his interpretation, sketching first its pre-Kantian theoretical context, and second discussing Hoffbauer’s Kantian interpretation of the concepts of will and the faculty of choice, and using the case of a lie as an illustration. (shrink)

In the attempt to understand and interpret behavioral patterns, collectively and individually, the example of the Amorion Dynasty is being used. Studying the texts on this topic by the chronographers of later periods, reveals a string of events that historians attributed to personal motives and attempted to interpret as the result o f the abovementioned feelings. This interpretation of the historical events, which did not consider the governmental, social and economic circumstances that allowed the range of human emotions to find (...) expression, is part of the contemporary perception of history. Without being anthropocentric, it does take into consideration the nature and emotions of leading figures and the collective behavior of people shaped by love or infatuation and are often expressed through hatred, rage and violence. (shrink)

The article focuses on the methodological specifics of qualitative sociological studies commissioned by public administration authorities (“the client”) which aim to provide solutions to specific problems defined by the client. In conducting this kind of study, the researcher is expected not only to describe and understand the existing state of affairs but also to provide a set of recommendations for amending it. The research terrain is not defined by the sociologist herself but basically by the client. This situation reveals a (...) series of methodological and epistemological issues. The article discusses some of them and proposes that the research strategy of heuristic investigation may be an answer to the associated dilemmas. The author argues that the correct use of reflexive methodology can help the researcher to overcome the limits imposed on the research by the client’s presence and even make the apparent disadvantages work for her. (shrink)