Wandlung und Bestand, von H. Jonas.--Die Bedeutung von Martin Heideggers Denken für die Methode der Theologie, von H. Ott.--Das befreite Nichts, von K. Harries.--Bevestigter Gesang; Bemerkungen zu Heideggers Hölderlin-Auslegung, von R.E. Schulz-Seitz.--Heidegger und das Problem einer "philosophischen" Anthropologie, von H. Fahrenbach.--"Das Sein und das Nichts," von E. Tugendhat.--Der Logos-Gedanke des Heraklit, von K. Held.--Platon und das Problem der Wahrheit, von W. Hirsch.--Sein und Cogitationes, von Fr.-W. von Herrmann.--Die Zeitlichkeit der Repräsentation, von W. Janke.--Wandlungen in der Kant-Auffassung Heideggers, von H. (...) Hoppe.--Dialectique et difference. par J. Taminiaux.--Nietzsche im Denken Heideggers, von E. Heftrich.--Remarques sur le rapport de Sein und Zeit et de la phénoménologie husserlienne, par G. Granel.--chiasma (romanized); Merleau-Ponty und Heidegger, von R. Boehm.--Heidegger vom anderen Ufer, von H. Patočka.--Der Spruch des Heidegger, von G. Petrović. (shrink)

When Heidegger's influence was at its zenith in Germany from the early fifties to the early sixties, most serious students of philosophy in that country were deeply steeped in his thought. His students or students of his students filled many if not most of the major chairs in philosophy. A cloud of reputedly Black Forest mysticism veiled the perspective of many of his critics and admirers at home and abroad. Droves of people flocked to hear lectures by him that most (...) could not understand, even on careful reading, much less on one hearing. He loomed so large that Being and Time frequently could not be seen as a highly imaginative, initial approach to a strictly limited set of questions, but was viewed either as an all-embracing first order catastrophy incorporating at once the most feared consequences of Boehme, Kierkegaard, Rilke, and Nietzsche, or as THE ANSWER. But most of that has past. Heidegger's dominance of German philosophy has ceased. One can now brush aside the larger-than-life images of Heidegger, the fears that his language was creating a cult phenomenon, the convictions that only those can understand him who give their lives to his thought. His language is at times unusually difficult, at times simple and beautiful. Some of his insights are obscure and not helpful, others are exciting and clarifying. One no longer expects Heidegger to interpret literature like a literary critic or an academic philologist. (shrink)

The Archaic takes as its major reference points C.G. Jung's classic essay, 'Archaic Man' (1930), and Ernesto Grassi's paper on 'Archaic theories of history' (1990). Moving beyond the confines of a Jungian framework to include other methodological approaches, this book explores the concept of the archaic. Defined as meaning 'old-fashioned', 'primitive', 'antiquated', the archaic is, in fact, much more than something very, very old: it is timeless, inasmuch as it is before time itself. Arch,̇ Urgrund, Ungrund, 'primordial darkness', 'eternal nothing' (...) are names for something essentially nameless, yet whose presence we nevertheless intuit. This book focuses on the reception of myth in the tradition of German Idealism or Romanticism (Creuzer, Schelling, Nietzsche), which not only looked back to earlier thinkers (such as Jacob Boehme) but also laid down roots for developments in twentieth-century thought (Ludwig Klages, Martin Heidegger). The Archaic also includes: - studies of the Germanic dimension of the archaic (Charles Bambach, Alan Cardew) - a discussion of the mytho-phenomenological approach to the archaic (Robert Josef Kozljani)̈ - a series of articles on Jung's understanding of the archaic (Paul Bishop, Susan Rowland, Robert Segal). This book will be of interest to psychoanalysts, anthropologists and phenomenologists, as well as students of psychology, cultural studies, religious studies, and philosophy, as it seeks to rehabilitate a concept of demonstrable and urgent relevance for our time. (shrink)

Ancient and medieval dialecticians: the lengthening shadow of Plato.--Traveller on the royal way: Martin Luther on simul justus et peccator.--Musician in the concert of God's joy: Jacob Boehme on ground and unground.--Prodigy between finite and infinite: Pascal's dialectic of grandeur and misery.--Thinker of the thoughts of God: Hegel and the dialectic of movement.--Venturer at the brinks: Kierkegaard and the dialectic of the suffering self.--Walker on the narrow ridge: Karl Barth and the dialectic of the human and divine.--Bridge-builder beyond the (...) boundaries: Tillich's dialectic of estrangement and reconciliation.--Wanderer in the forest: Heidegger on the being of beings.--Man suspended in mid-air: Rudolph Bultmann on the believer as free for the future.--Struggler under the twofold verdict of God: Werner Elert and the dialectic of law and gospel.--Epilog.--Selected bibliography (p. 159). (shrink)

This thought-provoking book discusses the concept of progress in economics and investigates whether any advance has been made in its different spheres of research. The authors look back at the history, successes and failures of their respective fields and thoroughly examine the notion of progress from an epistemological and methodological perspective. The idea of progress is particularly significant as the authors regard it as an essentially contested concept which can be defined in many ways – theoretically or empirically; locally or (...) globally; or as encouraging or impeding the existence of other research traditions. The authors discuss the idea that for progress to make any sense there must be an accumulation of knowledge built up over time rather than the replacement of ideas by each successive generation. Accordingly, they are not concerned with estimating the price of progress, reminiscing in the past, or assessing what has been lost. Instead they apply the complex mechanisms and machinery of the discipline to sub-fields such as normative economics, monetary economics, trade and location theory, Austrian economics and classical economics to critically assess whether progress has been made in these areas of research. -/- Bringing together authoritative and wide-ranging contributions by leading scholars, this book will challenge and engage those interested in philosophy, economic methodology and the history of economic thought. It will also appeal to economists in general who are interested in the advancement of their profession. (shrink)

Darwin's inner voice -- Living the virtuous life -- Of altruism and free riders -- Knowing our immediate predecessors -- Resurrecting some venerable ancestors -- A natural Garden of Eden -- The positive side of social selection -- Learning morals across the generations -- Work of the moral majority -- Pleistocene ups, downs, and crashes -- Testing the selection-by-reputation hypothesis -- The evolution of morals -- Epilogue: humanity's moral future.

Contemporary philosophers frequently assume that Kant never seriously engaged with Spinoza or Spinozism --certainly not before the break of Der Pantheismusstreit, or within the Critique of Pure Reason. Offering an alternative reading of key pre-critical texts and to some of the Critique's most central chapters, Omri Boehm challenges this common assumption. He argues that Kant not only is committed to Spinozism in early essays such as "The One Possible Basis" and "New Elucidation," but also takes up Spinozist metaphysics as Transcendental (...) Realism's most consistent form in the Critique of Pure Reason. (shrink)

Hume appeals to a mysterious mental process to explain how to world appears to possess features that are not present in sense perceptions, namely causal, moral, and aesthetic properties. He famously writes that the mind spreads itself onto the external world, and that we stain or gild natural objects with our sentiments. Projectivism is founded on these texts but it assumes a reading of Hume’s language as merely metaphorical. This assumption, however, conflicts sharply with the important explanatory role that “spreading” (...) and “staining” are supposed to play, which, ironically, is the very appeal of Hume’s texts to projectivists. In this paper, I first consider the difficulties readers of Hume have encountered in their attempts to ascertain nature of the key psychological process. I then identify in Hume’s texts novel theoretical resources that allow Hume to produce a satisfying answer to the question of process, that is, an account of the precise nature of the key process. I offer this explanation assuming what I take to be Hume’s austere conception of the elements involved in the process: sense impressions and “internal impressions” lacking intrinsic intentionality. On my reading, the spreading process explains the gap between the meager input and the rich, novel output: causal, moral and aesthetic judgments. (shrink)

In the Introduction to the Treatise Hume very enthusiastically announces his project to provide a secure and solid foundation for the sciences by grounding them on his science of man. And Hume indicates in the Abstract that he carries out this project in the Treatise. But most interpreters do not believe that Hume's project comes to fruition. In this paper, I offer a general reading of what I call Hume's ‘foundational project’ in the Treatise, but I focus especially on Book (...) 1. I argue that in Book 1 much of Hume's logic is put in the service of the other sciences, in particular, mathematics and natural philosophy. I concentrate on Hume's negative thesis that many of the ideas central to the sciences are ideas that we cannot form. For Hume, this negative thesis has implications for the sciences, as many of the texts I discuss make evident. I consider and criticize different proposals for understanding these implications: the Criterion of Meaning and the ‘Inconceivability Principle’. I introduce what I call Hume's ‘No Reason to Believe’ Principle, which I argue captures more adequately the link Hume envisions between his logic, in particular his examination of ideas, and the other sciences. (shrink)

The paper addresses two difficulties that arise in Treatise 1.2.5. First, Hume appears to be inconsistent when he denies that we have an idea of a vacuum or empty space yet allows for the idea of an “invisible and intangible distance.” My solution to this difficulty is to develop the overlooked possibility that Hume does not take the invisible and intangible distance to be a distance at all. Second, although Hume denies that we have an idea of a vacuum, some (...) texts in Treatise 1.2.5 are taken by interpreters to suggest that Hume nonetheless believes that there are vacuums in nature. I discuss the relevant texts and defend the view that Hume does not in fact countenance belief in vacuums. I conclude by outlining an interpretation of Hume’s intention in the Treatise that allows us to understand his discussion of ideas as having implications for the sciences. (shrink)

Drawing on Descartes' account of générosité, a reinterpretation of the Cogito is offered, emphasizing the role of the will. The paper's first part focuses on Cartesian ethics. It is argued that Descartes can be viewed as a Stoical thinker rather than a Baconian one. That is, he holds that theoretical contemplation is itself the primary ground of human happiness and tranquility of mind – experienced as the feeling of générosité. The paper's second part draws on the first in accounting for (...) the relation between radical doubt and certainty. By engaging with doubt, it is argued, the meditator comes to experience générosité, assert freedom. This experience is not, then, as argued by some, merely the Cogito's ethical counterpart. It is rather the Cogito's foundation. The meditator's assertion sum follows from – insofar as freedom is, as the definition of générosité asserts, ‘the only thing truly belonging to us', it consists in – the assertion of freedom. (shrink)

What is the source of normativity in Hume’s account of causal reasoning? In virtue of what are causal beliefs justified for Hume? To answer these questions, the literature appeals, almost invariably, to custom or some feature thereof. I argue, in contrast, that causal beliefs are justified for Hume because they issue from experience. Although he denies experience the title of justifying reason, for Hume experience has normative authority. I offer an interpretation of the source and nature of the normativity of (...) experience in causal reasoning. I argue that the senses and memory have a special, positive status within the mind in virtue of their force and vivacity, which, on my reading, Hume identifies with a sense of presentness and a strong effect on the mind. Hume dignifies the system of memory and the senses with the title of reality because of these features. Causal beliefs are dignified as “realities” because they issue from reality. However, because the imagination can sometimes enhance the force and vivacity of ideas without the help of experience, Hume appeals to coherence and general rules as well. (shrink)

Theoretical and practical trends of corporate citizenship indicate a deepening partnership between business and community. Following these developments, the article develops a model for the participation of businesses in decision-making processes as part of policy making and social-economic planning in the community. The article focuses on three levels: It examines the benefits and risks of such participation; identifies the typical dimensions of the participation processes; and finally, provides guidelines on how to develop a participation strategy based on the unique conditions (...) of each business and community. (shrink)

: The question of Kant’s relation to Spinozist thought has been virtually ignored over the years. I analyze Kant’s pre-critical ‘possibility-proof’ of God’s existence, elaborated in the Beweisgrund, as well as the echoes that this proof has in the first Critique, in beginning to uncover the connection between Kant’s thought and Spinoza’s. Kant’s espousal of the Principle of Sufficient Reason [PSR] for the analysis of modality during the pre-critical period committed him, I argue, to Spinozist substance monism. Much textual evidence (...) suggests that he was aware of this commitment. However, by transforming the PSR into a regulative principle the critical Kant has transformed his pre-critical proof into a regulative ideal. He is thereby committed, I argue, to regulative Spinozism. (shrink)

[1.] Husserl-Studien -- 2. Bd. Studien zur Phänomenologie der Epoché.

A reading of Hume's famous Conclusion to Book 1 of the Treatise.

Using criteria of relative plausibility, it is possible to make a case for significant group selection over the 100,000 years that Anatomically Modern Humans have been both moral and egalitarian. Our nomadic forebears surely lived in egalitarian communities that levelled social differences and moralistically curbed free-riding behaviour, and this egalitarian syndrome would have had profound effects on levels of selection. First, it reduced phenotypic variation at the within-group level. Second, it increased phenotypic variation at the between-group level. Third, and crucially, (...) moral sanctioning also permitted groups to sharply curtail free-riding tendencies at the level of phenotype. The result was group selection strong enough to support altruistic genes, and a human nature that was set up for social ambivalence: that nature was mainly selfish and strongly nepotistic, but it was at least modestly and socially significantly altruistic. The effects on human social and moral life were pervasive, both in hunting bands and in more recent manifestations of human society. (shrink)

Hume establishes a link between our capacity to conceive or form “clear and distinct ideas” and metaphysical possibility. Hume’s so-called Conceivability Principle is usually assumed to be epistemic: conceivability is supposed to inform us of independent metaphysical facts. In this chapter, however, I argue that Hume is not engaged in modal epistemology. For Hume, there is no epistemic relation between conceivability and an independent metaphysical world of possibilities. On my reading, conceivability is more like the “mètre étalon” in Paris—the standard (...) unit of measurement of length—than a window or telescope into some metaphysical world. Conceivability is the standard of metaphysical possibility. And just as the meter is defined as a certain distance of light traveled, for Hume, conceivability is defined in terms of the liberty of the imagination. I discuss how Hume deploys conceivability along with knowledge—the standard of metaphysical necessity—as tools for measuring or assessing the alleged metaphysical necessity of a cause to every beginning of existence and the alleged rational foundation of causal inferences. (shrink)

Research studies on Corporate Social Responsibility often focus on revealing corporate leaders’ attitudes toward various issues of CSR. The position of the present paper is that to understand CSR, we must grasp the collaborative perspective of CSR, and discern the attitudes of community leaders as well as corporate leaders. To this end, the study compares attitudes of community leaders with those of corporate leaders in three localities in Israel. The study examines various issues of CSR, highlighting the benefits to both (...) community and corporation of reciprocal relations. Results from t‐tests confirmed significant differences between the groups. Some important implications for CSR particularly in terms of collaboration between community and corporation are discussed. (shrink)

Kant's attack on metaphysics consists in large part in his attack on a principle that he names the Supreme Principle of Pure Reason. This principle, it is not often noticed, is the Principle of Sufficient Reason [PSR]. In interpreting this principle as such, I argue that Kant's attack on the PSR depends on Kant's claim that existence is not a first-order predicate. If existence isn't what Kant calls a real predicate, the PSR is false. While this constitutes a powerful Kantian (...) argument against dogmatic rationalism, it also poses a problem for Kant. For, as I argue, if the PSR is true, Kant's argument that existence isn't a first-order predicate is false. In this sense, Kant's attack on the PSR is begging the question vis-á-vis radical metaphysicians. Concluding the paper I suggest relying on Kant's 'is'/'ought' distinction in avoiding this circularity, thereby reinforcing the Kantian critique. (shrink)

The article traces out the history of the evolution in meaning of the phenomenological reduction in husserl's writings. The starting point is husserl's conviction that what is lacking most to philosophy as well as to science is a truly rigorous scientific method. Already in the "logical investigations" (1901) the phenomenological reduction is presented as the core of this method. But here this reduction is understood as a deliberate restriction or limitation of the mind to what is adequately perceived in an (...) "adequately fulfilling intuition" within the immanence of consciousness, Excluding any transcendence. In his lectures on "the idea of phenomenology" a significant expansion of the notion of reduction begins to appear. There is still the insistence on the absolutely given, But this now begins to include a certain "real transcendence" extending beyond the sphere of "real immanence to consciousness." this change appears first in his published works in the "ideas" of 1913. (shrink)

Scholars commonly assume that Kant never seriously engaged with Spinoza or Spinozism. However, in his later writings Kant argues several times that Spinozism is the most consistent form of transcendental realism. In the first part of the paper, I argue that the first Antinomy, debating the age and size of the world, already reflects Kant's confrontation with Spinozist metaphysics. Specifically, the position articulated in the Antithesis ? according to which the world is infinite and uncreated ? is Spinozist, not Leibnizian, (...) as commonly assumed. In the second part of the paper, I raise the chief Spinozist challenge to the Antinomy, arising from Spinoza's reliance on a cosmological `totum analyticum' ? an infinite whole which is prior to its parts. In conclusion, I begin to elaborate a defence of the Kantian position, confronting Spinoza's infinite whole with Kant's account of the absolutely infinite in his discussion of the sublime. (shrink)

Hume appeals to different kinds of certainties and necessities in the Treatise. He contrasts the certainty that arises from intuition and demonstrative reasoning with the certainty that arises from causal reasoning. He denies that the causal maxim is absolutely or metaphysically necessary, but he nonetheless takes the causal maxim and ‘proofs’ to be necessary. The focus of this paper is the certainty and necessity involved in Hume’s concept of knowledge. I defend the view that intuitive certainty, in particular, is certainty (...) of the invariability or necessity of relations between ideas. Against David Owen and Helen Beebee, I argue that the certainty involved in intuition depends on the activity of the mind. I argue, further, that understanding this activity helps us understand more clearly one of Hume’s most important theses, namely that experience is the source of a distinct kind of certainty and of necessity. (shrink)

Hume’s views concerning the existence of body or external objects are notoriously difficult and intractable. The paper sheds light on the concept of body in Hume’s Treatise by defending three theses. First, that Hume’s fundamental tenet that the only objects that are present to the mind are perceptions must be understood as methodological, rather than metaphysical or epistemological. Second, that Hume considers legitimate the fundamental assumption of natural philosophy that through experience and observation we know body. Third, that many of (...) the contradictions and difficulties that interpreters attribute to Hume’s concept of body should be attributed instead, as Hume does, to every system of philosophy. (shrink)

Michael Tomasello’s account of moral evolution includes both a synthesis of extensive experimental work done on humans and chimpanzees on their potential for perspective-taking and helpful, altruistic generosity and a major emphasis on “collective intentionality” as an important component of morality in humans. Both will be very useful to the evolutionary study of this subject. However, his disavowal of collective intentions on the parts of chimpanzees would appear to be empirically incorrect, owing to reliance on experimental captive research focused only (...) on dyadic interactions. Here, evidence to the contrary is provided from studies of wild chimpanzees as they naturally cooperate in sizable groups. Collective intentions are inferable when they go on patrol, when they mob predators, when they go hunting, and when large coalitions gang-attack disliked members of the same community. This last behavior has particularly significant pre-adaptive implications for the evolution of moralistic social control, and it suggests that moral evolution has deep roots, going back to the Last Common Ancestor of humans, bonobos, and chimpanzees. (shrink)

What do Albert Einstein and Pablo Picasso have in common? Can we learn about science by studying art? There are many connections just waiting to be discovered between the natural world and artistic techniques that have been used for centuries. Author and retired science educator Mary Kirsch Boehm systematically guides readers through a look at science with an artistic eye, introducing an integrated and often overlooked view of the two disciplines. By exploring the materials and techniques of art and the (...) science behind them, Boehm reveals just how interconnected our world really is. (shrink)

Understanding aging and how it affects an organism's lifespan is a fundamental problem in biology. A hallmark of aging is stem cell senescence, the decline of functionality, and number of somatic stem cells, resulting in an impaired regenerative capacity and reduced tissue function. In addition, aging is characterized by profound remodeling of the immune system and a quantitative decline of adequate immune responses, a phenomenon referred to as immune‐senescence. Yet, what is causing stem cell and immune‐senescence? This review discusses experimental (...) studies of potentially immortal Hydra which have made contributions to answering this question. Hydra transcription factor FoxO has been shown to modulate both stem cell proliferation and innate immunity, lending strong support to a role of FoxO as critical rate‐of‐aging regulator from Hydra to human. Constructing a model of how FoxO responds to diverse environmental factors provides a framework for how stem cell factors might contribute to aging. (shrink)

Proponents of the standard evolutionary biology paradigm explain human “altruism” in terms of either nepotism or strict reciprocity. On that basis our underlying nature is reduced to a function of inclusive fitness: human nature has to be totally selfish or nepotistic. Proposed here are three possible paths to giving costly aid to nonrelatives, paths that are controversial because they involve assumed pleiotropic effects or group selection. One path is pleiotropic subsidies that help to extend nepotistic helping behavior from close family (...) to nonrelatives. Another is “warfare”—if and only if warfare recurred in the Paleolithic. The third and most plausible hypothesis is based on the morally based egalitarian syndrome of prehistoric hunter-gatherers, which reduced phenotypic variation at the within-group level, increased it at the between-group level, and drastically curtailed the advantages of free riders. In an analysis consistent with the fundamental tenets of evolutionary biology, these three paths are evaluated as explanations for the evolutionary development of a rather complicated human social nature. (shrink)

In his discussion of our idea of time in the Treatise, Hume makes the perplexing claim that unchanging objects cannot be said to endure. While Hume is targeting the Newtonian conception of absolute time, it is not at all clear how his denial that unchanging objects are in time fits with this target. Moreover, Hume diagnoses our belief that unchanging objects endure as the product of a psychological fiction, but his account of this fiction is also riddled with puzzling claims (...) about our experience of unchanging objects. In this paper, we argue that Hume’s claims are a lot less baffling and indeed, much more sophisticated than they appear. We do so by considering his arguments as a response to Locke’s specific approach to the concept of absolute time. (shrink)

The last few decades have witnessed intense debates in Hume scholarship concerning Hume’s account of causation. At the core of the “old–new Hume” debate is the question of whether causation for Hume is more than mere regularity, in particular, whether Hume countenances necessary connections in mind-independent nature. This chapter assesses this debate against the background of Hume’s “foundational project” in the Treatise. The question of the role and import of Hume’s account of the idea of cause is examined and compared (...) with Hume’s treatment of other ideas. (shrink)

an der Universität Göttingen gehaltenen Vcwlesung über Hauptstücke aus der Phänomenologie und Theorie der Erkenntnis,l ist annähernd voll­ ständig erhalten; die Blätter des V cwlesungsmanuskripts zur Phänomenologie des inneren Zeitbewußtseins liegen verstreut in den Konvoluten F I 6 und 2 F I 8 des Husserl-Archivs zu Löwen. Allerdings fußt der Erste Teil des Erstdrucks, dessen Bezeichnung als Die Vorlesungen über das innere Zeit­ bewußtsein aus dem Jahre 1905 gleichwohl auch in vcwliegender Neuausgabe beibehalten wurde, nur zum Teil noch, und auch (...) in diesem Teil mit be­ trächtlichen Abweichungen, auf dem Text des ursprünglichen Vcwlesungs­ manuskripts des Jahres I905; und umgekehrt hat nur ein Teil des Textes des ursprünglichen Vcwlesungs-Manuskripts - mit den erwähnten Abwand­ lungen - Eingang in den Ersten Teil des Erstdrucks gefunden. Wo der Text dieses Ersten Teils des Erstdrucks dem des ursprünglichen Vcwlesungs­ manuskripts entspricht, wurde er er mit diesem verglichen, und ollensicht­ liche Irrtümer im Erstdruck wurden berichtigt; in den Textkritischen Anmer­ kungen ist dann mit dem Vermerk nach dem Ms. verbessert die Text­ fassung des Erstdrucks wiedergegeben. Ferner wurde in den Textkritischen Anmerkungen vcwliegender Neuausgabe überall der ursprüngliche und voll­ ständige· Text des Vorlesungsmanuskripts von I905 wiedergegeben, auf dessen Zusammenhang die entsprechenden Teile des Erstdrucks zurückgehen, wo dieser von ienem abweicht. Einige zum V cwlesungsmanuskript gehörige Blätter, deren Text sich iedoch nicht zusammenhängend dem übrigen einfügt, wurden im vcwliegenden Band unter B (S. 135-382) mit abgedruckt. Die 1 Vgl. oben die "Einleitung des Herausgebers", S. XIV-XVII. (shrink)

Hunter-gatherer punishment involves costs and benefits to individuals and groups, but the costs do not necessarily fit with the assumptions made in models that consider punishment to be altruistic – which brings in the free-rider problem and the problem of second-order free-riders. In this commentary, I present foragers' capital punishment patterns ethnographically, in the interest of establishing whether such punishment is likely to be costly; and I suggest that in many cases abstentions from punishment that might be taken as defections (...) by free-riders are actually caused by social-structural considerations rather than being an effect of free-rider genes. This presentation of data supplements the ethnographic analysis provided by Guala. (shrink)

Nach wissenschaftlichen Schätzungen gibt es auf diesem Planeten Menschen seit etwa einer halben Million Jahre. Gleichwohl drohen die überall um sich greifenden, scheinbar aus den verschiedensten Quellen sich nährenden Vorstellungen universaler Entwicklung der Behauptung, daß solche Wesen—Menschen—wirklich existieren, den Boden zu entziehen. Denn diese Behauptung muß bedeuten, daß mit dem Auftreten von Menschen—als Wesen eigener Art—ein ihnen spezifisch eigenes, zuvor ungekanntes Wirkungsvermögen in die Welt eingetreten ist und, soweit es reicht und sich auswirkt, die Wirklichkeit dieser Welt verändert hat. Solche (...) Veränderungen der Welt im Wirkungsbereich des Menschen und in Folge seiner insbesondere auf seine Wissenschaft sich stützenden Wirksamkeit scheinen ja auch sichtbar genug. Doch gerade im Namen dieser ihrer Wissenschaft wollen moderne Menschen diese Veränderungen eher nur der Entwicklung zuschreiben als einem geheimnisvollen Wirkungsvermögen ganz eigenartiger Wesen, die da mitten unter uns unter dem Namen von “Menschen” existierten, ja denen man gar uns selber zurechnen wollte. (shrink)

In this article, the author explains the context and circumstances in which he begun, back in the 60s, the first French translation of Sein und Zeit, in collaboration with Alphonse de Waehlens. The article describes the methods and perspectives the first French translators adopted during their work of translation. The article ends with a few considerations concerning the incompleteness of the Heideggerian’s project of Sein und Zeit, explaining this nonachievement by Heidegger’s abandonment of the existential perspective he assumed in Sein (...) und Zeit. (shrink)

Many proteins responsible for genome maintenance interact with one another via short sequence motifs. The best known of these are PIP motifs, which mediate interactions with the replication protein PCNA. Others include RIR motifs, which bind the translesion synthesis protein Rev1, and MIP motifs, which bind the mismatch repair protein Mlh1. Although these motifs have similar consensus sequences, they have traditionally been viewed as separate motifs, each with their own target protein. In this article, we review several recent studies that (...) challenge this view. Taken together, they imply that these different motifs are not distinct entities. Instead, there is a single, broader class of motifs, which we call “PIP‐like” motifs, which have overlapping specificities and are capable of binding multiple target proteins. Given this, we must reassess the role of these motifs in forming the network of interacting proteins responsible for genome maintenance. (shrink)

Interpreters have found it exceedingly difficult to understand how Hume could be right in claiming that his two definitions of ‘cause’ are essentially the same. As J. A. Robinson points out, the definitions do not even seem to be extensionally equivalent. Don Garrett offers an influential solution to this interpretative problem, one that attributes to Hume the reliance on an ideal observer. I argue that the theoretical need for an ideal observer stems from an idealized concept of definition, which many (...) interpreters, including Garrett, attribute to Hume. I argue that this idealized concept of definition indeed demands an unlimited or infinite ideal observer. But there is substantial textual evidence indicating that Hume disallows the employment of idealizations in general in the sciences. Thus Hume would reject the idealized concept of definition and its corresponding ideal observer. I then put forward an expert-relative reading of Hume’s definitions of ‘cause’, which also renders both definitions extensionally equivalent. On the expert-relative reading, the meaning of ‘cause’ changes with better observations and experiments, but it also allows Humean definitions to play important roles within our normative practices. Finally, I consider and reject Henry Allison’s argument that idealized definitions and their corresponding infinite minds are necessary for expert reflection on the limitations of current science. (shrink)