Abortion is largely accepted even for reasons that do not have anything to do with the fetus' health. By showing that (1) both fetuses and newborns do not have the same moral status as actual persons, (2) the fact that both are potential persons is morally irrelevant and (3) adoption is not always in the best interest of actual people, the authors argue that what we call ‘after-birth abortion’ (killing a newborn) should be permissible in all the cases where abortion (...) is, including cases where the newborn is not disabled. (shrink)

This paper argues for a representational semantic conception of scientific theories, which respects the bare claim of any semantic view, namely that theories can be characterised as sets of models. RSC must be sharply distinguished from structural versions that assume a further identity of ‘models’ and ‘structures’, which we reject. The practice-turn in the recent philosophical literature suggests instead that modelling must be understood in a deflationary spirit, in terms of the diverse representational practices in the sciences. These insights are (...) applied to some mathematical models, thus showing that the mathematical sciences are not in principle counterexamples to RSC. (shrink)

The paper provides a new critical perspective on the propensity interpretation of fitness, by investigating its relationship to the propensity interpretation of probability. Two main conclusions are drawn. First, the claim that fitness is a propensity cannot be understood properly: fitness is not a propensity in the sense prescribed by the propensity interpretation of probability. Second, this interpretation of probability is inessential for explanations proposed by the PIF in evolutionary biology. Consequently, interpreting the probabilistic dimension of fitness in terms of (...) propensities is neither a strong motivation in favor of this interpretation, nor a possible target for substantial criticism. (shrink)

Gothic literature—a genre brimming with madness, supernaturalism, and psychological terror—offers innumerable case studies potentially representing how psychiatric patients perceive their treatment from healthcare professionals. Charlotte Perkins Gilman’s famous 1892 short story “The Yellow Wallpaper” offers a poignant example of this through its fictional narrator, a diarist many interpret to be suffering from postpartum depression. The fiction here does not stray far from reality: Gilman orchestrated her diarist’s experience to mirror her own, as both real author and fictional character suffocated from (...) a melancholy only made worse by their physicians’ insistence on following the “Rest Cure.” While this instruction to cease all work and activity was a prevalent depression treatment at the time, Gilman, through “The Yellow Wallpaper,” reveals how the intervention ultimately harmed more than helped because it overlooked her—and, by extension, her fictional diarist’s— unique needs and identities. Today, while the ineffective Rest Cure no longer exists, applying observations from “The Yellow Wallpaper” to clinical research calls attention to underrepresentation in treatment development, a costly problem that could be mitigated by mindful incorporation of intersectionality theory into study designs. (shrink)

In this paper we explore the thesis that the role of argumentation in practical reasoning in general and legal reasoning in particular is to justify the use of defeasible rules to derive a conclusion in preference to the use of other defeasible rules to derive a conflicting conclusion. The defeasibility of rules is expressed by means of non-provability claims as additional conditions of the rules.We outline an abstract approach to defeasible reasoning and argumentation which includes many existing formalisms, including default (...) logic, extended logic programming, non-monotonic modal logic and auto-epistemic logic, as special cases. We show, in particular, that the admissibility semantics for all these formalisms has a natural argumentation-theoretic interpretation and proof procedure, which seem to correspond well with informal argumentation. (shrink)

The notion of grounding is usually conceived as an objective and explanatory relation. It connects two relata if one—the ground—determines or explains the other—the consequence. In the contemporary literature on grounding, much effort has been devoted to logically characterize the formal aspects of grounding, but a major hard problem remains: defining suitable grounding principles for universal and existential formulae. Indeed, several grounding principles for quantified formulae have been proposed, but all of them are exposed to paradoxes in some very natural (...) contexts of application. We introduce in this paper a first-order formal system that captures the notion of grounding and avoids the paradoxes in a novel and non-trivial way. The system we present formally develops Bolzano’s ideas on grounding by employing Hilbert’s ε-terms and an adapted version of Fine’s theory of arbitrary objects. (shrink)

This paper deals with phenomenological distinctions concerning empathy with real persons and empathy with fictional characters. We will introduce both contemporary accounts of our perception of others and Edith Stein’s account of empathy. These theories will turn out to be fruitful in defending our main thesis, i.e. that the differences between empathy with real people and empathy with fictional characters are not structural but just qualitative. We will argue that in both cases empathy is a direct act of perceiving others (...) and their lived experience. However, stemming from Stein’s work, we will underline that empathy with real persons is in principio more vivid and intense than empathy with fictional characters. In order to identify similarities and differences between empathy de vivo and empathy in fiction, we will focus on the following issues: the quality of perception; the motivational context and the “life-world context”; the ontological status of persons vs. characters. (shrink)

Individual and collective ethical stances regarding ethical consumption and related outcomes are usually seen as both a form of concern about extant market offerings and as opportunities to develop new offerings. In this sense, demand and supply are traditionally portrayed as interacting dialectically on the basis of extant business models. In general, this perspective implicitly assumes the juxtaposition of demand side ethical stances and supply side corporate initiatives. The Eataly story describes, however, a different approach to market transformation; in this (...) case a company and a social movement (Slow Food) have negotiated and collaborated prior to initiating a new business model. This collaboration process and its outcomes are described, focusing specifically on ordinary Eataly customers’ and Slow Food members’ reactions. Given that Eataly can be regarded as a case of mainstreaming, ordinary customers seem satisfied with the new offering and the Slow Food support for the initiative; the more purist members of the Slow Food movement had critical concerns, however, as happened in similar conditions, according to literature, with regard to Fair Trade. The Slow Food endorsement of the new venture has also been observed from the attitude–behaviour gap perspective, as it contributed to addressing the factors affecting the gap between attitudes and actual behaviours. Extensive qualitative data were collected and analysed over a 3-year period. The main study implications refer to the ways in which companies and social movements could interact to co-design new business models, as well as outlining consumers’ attitudes and behaviours towards such new offerings. (shrink)

Accelerating environmental uncertainty and the need to cope with increasingly complex market and social demands, combine to create high value for the intuitive approach to decision-making at the strategic level. Research on intuition suffers from marked fragmentation, due to the existence of disciplinary silos based on diverse, apparently irreconcilable, ontological and epistemological assumptions. Not surprisingly, there is no integrated interdisciplinary framework suitable for a rich account of intuition, contemplating how affect and cognition intertwine in the intuitive process, and how intuition (...) scales up from the individual to collective decision-making. This study contributes to the construction of a broad conceptual framework, suitable for a multi-level account of intuition and for a fruitful dialogue with distant research areas. It critically discusses two mainstream conceptualizations of intuition which claim to be grounded in a cross-disciplinary consensus. Drawing on the complexity paradigm, it then proposes a conceptualization of intuition as emergence. Finally, it explores the theoretical and practical implications. (shrink)

This book presents a unique rethinking of G. W. F. Hegel's philosophy from unusual and controversial perspectives in order to liberate new energies from his philosophy. The role Hegel ascribes to women in the shaping of society and family, the reconstruction of his anthropological and psychological perspective, his approach to human nature, the relationship between mental illness and social disease, the role of the unconscious, and the relevance of intercultural and interreligious pathways: All these themes reveal new and inspiring aspects (...) of Hegel’s thought for our time. (shrink)

In his target article, Ismaili M’hamdi advocates for perfectionist public health policymaking, which entails fostering relevant and objectively valuable public health-related capabilities wh...

Objective. Tako-Tsubo syndrome (TTS) is historically related to the occurrence of psychological (emotional) factors (“broken heart” syndrome). Our aim was conducting a systematic review analyzing the role of psychological factors in TTS. Methods: All studies on TTS and psychological factors from 1991 to April 2019 were scrutinized according to the Cochrane Collaboration and the PRISMA statement. Selected studies were additionally evaluated for the Risk of Bias according to the Newcastle-Ottawa Scale (NOS). Results. Fifteen case-control studies (Mayo Clinic criteria) were finally (...) selected. Most studies analysed the role of stressful life-events or trauma, although with conflicting findings, while a likely role for long-lasting psychological distress seems to be a homogenous result. Among life-time psychopathology, only anxiety seems to have a significant role. Some studies outlined a likely role for personality, but findings are conflicting. Conclusion. A role for psychological factors in TTS requires more studies with stronger research methodology than the existing ones. (shrink)

The Machiavellian intelligence hypothesis and the social brain hypothesis have revolutionized traditional views on how primate cognition can be studied. Beyond the study of individual problem-solving capacities of various primates, these hypotheses have demonstrated the close relationship between the complexity of primate social life and the emergence of more sophisticated cognitive skills. The social brain hypothesis demonstrated the existence of a close correlation between the volume of the neocortex and the number of individuals in primate social groups. The amount of (...) studies in this area have increased dramatically and have successfully enhanced our understanding of the evolutionary roots of complex social phenomena, including theory of mind, cultural transmission, social learning, and shared attention. The cognitive capacities present in primates also underlie the evolution of cognitive capacities in humans. This chapter introduces present avenues taken in research on primate social cognition, and it walks the reader through the chapters of this volume. (shrink)

The Developmental Systems Theory (DST) presented by its proponents as a challenging approach in biology is aimed at transforming the workings of the life sciences from both a theoretical and experimental point of view (see, in particular, Oyama [1985] 2000; Oyama et al. 2001). Even though some may have the impression that the enthusiasm surrounding DST has faded in very recent years, some of the key concepts, ideas, and visions of DST have in fact pervaded biology and philosophy of biology. (...) It seems crucial to us both to establish which of these ideas are truly specific to DST, and to shift through these ideas in order to determine the criticisms they have drawn, or may draw (e.g., Sterelny et al. 1996; Griesemer 2000; Sterelny 2000; Kitcher 2001; Keller 2005; Waters 2007). (shrink)

Verbs are more difficult to produce than nouns. Thus, if executive resources are reduced as in Parkinson's disease (PD), verbs are penalized compared to nouns. However, in an experimental condition in which it is the noun that must be selected from a larger number of alternatives compared to the verb, it is the noun production that becomes slower and more prone to errors. Indeed, patients are slower and less accurate than normal subjects when required to produce nouns from verbs (VN) (...) in a morphology derivation tasks (e.g., “osservazione” from “osservare”) [“observation” from “observe”] than verbs from nouns in a morphology generation task, in which only a verb can be generated from the noun (NV) (e.g., “fallire” from “fallimento”) [“to fail” from “failure”]. In the Italian language morphology, in fact, generation and derivation tasks differ in the number of lexical entries among which the response must be selected. The left Inferior Frontal Gyrus (IFG) has been demonstrated to be involved in selection processes. In the present study, we explored if the ability to select words is related to the cortical thickness of the left IFG. Twelve right-sided PD with nigrostriatal hypofunctionality in the left hemisphere (RPD-LH), 9 left-sided PD with nigrostriatal hypofunctionality in the right hemisphere (LPD-RH) and 19 healthy controls (HC) took part in the study. NV and VN production tasks were administered; accuracy and reaction times (RTs) were collected. All 40 subjects received a structural MRI examination. Cortical thickness of the IFG and volumetric measurements for subcortical regions, thought to support selection processes, were computed using FreeSurfer. In VN derivation tasks RPD-LH patients were less accurate than LPD-RH patients (accuracy: 66% vs. 77%). No difference emerged among the three groups in RTs. Task accuracy/RTs and IFG thickness showed a significant correlation only in RPD-LH. Not only nouns (as expected) but also verbs were correlated with cortical thickness. This suggests that the linguistic nature of the stimuli along with executive resources are both relevant during word selection processes. Our data confirm that executive resources and language interact in the left IFG in word production tasks. (shrink)

Ivancovsky et al. argue that the neurocognitive mechanisms of creativity and curiosity both rely on the interplay among brain networks. Research to date demonstrates that such inter-network dynamics are further complicated by functional fractionation within networks. Investigating how networks subdivide and reconfigure in service of a task offers insights about the precise anatomy that underpins creative and curious behaviour.

This volume highlights important aspects of the complex relationship between common language and legal practice. It hosts an interdisciplinary discussion between cognitive science, philosophy of language and philosophy of law, in which an international group of authors aims to promote, enrich and refine this new debate. Philosophers of law have always shown a keen interest in cognitive science and philosophy of language in order to find tools to solve their problems: recently this interest was reciprocated and scholars from cognitive science (...) and philosophy of language now look to the law as a testing ground for their theses. Using the most sophisticated tools available to pragmatics, sociolinguistics, cognitive sciences and legal theory, an interdisciplinary, international group of authors address questions like: Does legal interpretation differ from ordinary understanding? Is the common pragmatic apparatus appropriate to legal practice? What can pragmatics teach about the concept of law and pervasive legal phenomena such as testimony or legal disagreements? (shrink)

Die Philosophie Helmuth Plessners hat in den letzten Jahren eine Renaissance erfahren: Plessner wurde als relevanter Vertreter einer Biophilosophie (wieder) entdeckt, die nicht nur die uberkommene Trennung von Natur und Kultur, sondern auch die Gegenuberstellung disjunkter Wissenschaftskulturen in Frage stellt und ihr Verhaltnis neu bestimmt. DAs Buch nimmt die verschiedenen disziplinaren Faden auf, die die Konzeption von Plessners Biophilosophie insbesondere in den Stufen des Organischen und der Mensch (1928) verstandlich machen. ES stellt Plessners uberlegungen im Kontext von naturwissenschaftlichen (von Uexkull, (...) Buytendijk, Driesch, von Weizsacker, Portmann, Kohler) sowie philosophischen (Bergson, Misch, Hartmann, Scheler, Heidegger, Jonas) Theorien seiner Zeit vor. (shrink)

This paper develops a dialogue on value and measurement in education that began at a special symposium at ECER in September 2015. The paper seeks to continue the dialogue by commenting on the main respondent’s contribution from Network 9. We hope to clarify how different sides of the assessment debate can be misunderstood by others. What emerges in our paper is suggestive but nonetheless points to how thinking in opposing camps can limit our understanding of assessment as a human activity. (...) Taking up key points made by the respondent to the symposium, we focus on the comparison between the requirements of design in technological problem-solving situations and those that arise when we take seriously the requirements of assessment and valuing as a human activity. This discussion sets up a wider analysis of the problem of ethics across the sciences and humanities historically. While remaining tentative, the discussion points to a particular problem related to our ability to defend practical rationality agains.. (shrink)

In the present paper, we will attempt to gain hints regarding the nature of tactile awareness in humans. At first, we will review some recent literature showing that an actual tactile experience can emerge in absence of any tactile stimulus (e.g., tactile hallucinations, tactile illusions). According to the current model of tactile awareness, we will subsequently argue that such (false) tactile perceptions are subserved by the same anatomo-functional mechanisms known to underpin actual perception. On these bases, we will discuss the (...) hypothesis that tactile awareness is strongly linked to expected rather than actual stimuli. Indeed, this hypothesis is in line with the notion that the human brain has a strong predictive, rather than reactive, nature. (shrink)

In my paper, I will address two issues on the characterisation of social objects as subject-dependent objects: (i) Does phenomenological realism imply Platonism in social ontology? (ii) Which type of intentionality is the protagonist of social objects’ existential dependence on subjects? Both questions deal with Ferraris’ reception of Reinach’s phenomenological realism, on the one hand, and with the role played by the intentionality of social acts in the constitution of social objects, on the other (Reinach 1913, Ferraris 2009). According to (...) Ferraris, Reinach’s phenomenological realism becomes a sort of “social Platonism”, and the intentionality of social acts is an individual intentionality. On the contrary, I will maintain that phenomenological realism does not imply social Platonism in social ontology, and that social intentionality is not an individual and solitary intentionality: it is, rather, a heterotropic intentionality which necessarily refers to and depends on other subjects. (shrink)

In this case-report we describe an experience where alternative places – rather than the classroom – are exploited to implement learning processes. We maintain that this experience is a good example of materiality because it focuses on a project where students had the opportunity to re-design a public space. To this aim, various objects and tools are used to support discussions and exchanges with new stakeholders. Our theoretical vision combines Piaget’s and Vygotsky’s tradition with an innovative framework called the Trialogical (...) Learning Approach (TLA). From such theoretical background an idea of materiality emerges, that refers to material in combination with the social relationships developed around the material. Our case-report concerns a participatory project run by Rete Dialogues, a national school network focusing on global citizenship education. Our research question is: how can this project highlight the connection between the TLA and socio-materiality? Since 2017, around 200 students (age 7-16) and 20 teachers from different schools have been engaged in tackling the degradation of an important square in Rome. The project – “Dialogues in the Square” (DiS) was developed with several stakeholders that contributed to the understanding of critical issues influencing the maintenance of the square, in the perspective of planning, and possibly implementing improvements proposed by students. Crucial is the cooperation with two important urban art projects: i) the pilot-project MACRO-ASILO, run by the MACRO museum in Rome and aimed at connecting the world of art with the city life; ii) the “building sites” of the Rome Rebirth Forum, inspired by the world-known artist Michelangelo Pistoletto’s “third paradise” methodology, that encourages responsibility and action taking on sustainability through art. Drawing on data collected through direct observations and video recordings, we aim to show and make sense of the connection between the TLA and socio-materiality, highlighting three key elements: the flexible use of mediation tools, the overcoming of the dichotomy between individual and collective learning through reflection, and the re-shaping of social practices. (shrink)

Apoptotic pathways have always been regarded as a key‐player in preserving tissue and organ homeostasis. Excessive activation or resistance to activation of cell death signaling may indeed be responsible for several mechanisms of disease, including malignancy and chronic degenerative diseases. Therefore, targeting apoptotic factors gained more and more attention in the scientific community and novel strategies emerged aimed at selectively blocking or stimulating cell death signaling. This is also the case for the TMEM219 death receptor, which is activated by a (...) circulating ligand, the Insulin‐like growth factor binding protein 3 (IGFBP3) and induces a caspase‐8‐dependent apoptosis of the target cells. Interestingly, stimulation of the IGFBP3/TMEM219 axis exerts an anti‐proliferative effect, while blockade of the TMEM219 deleterious signal protects TMEM219‐expressing cells of the endocrine pancreas, lung, and intestine from damage and death. Here, we summarize the most updated reports on the role of the IGFBP3/TMEM219 apoptotic axis in disease conditions, including intestinal disorders and diabetes, and we describe the advancements in designing and testing novel TMEM219‐based targeting approaches in emerging potential clinical applications. (shrink)

In Memory, History, Forgetting, Ricœur does not provide us with a clear definition of collective memory. In this article, we will try to show how it could nevertheless be described, based on the same text, as the capacity for recognition, by way of reciprocal attribution, memories that are engraved in temporal spaces and are shared with our neighbors and, through them, with strangers. To verify this hypothesis, we will analyse Ricœur’s reflection on architecture as public memory’s engraving into space, presented (...) for the first time in the text “Architecture et narrativité.” Lastly, we will consider imagination and bodily memory, i.e. habit emanating from the act of inhabiting, as the conditions of possibility for the crystallization of memories in shared places. (shrink)

Flavonoids are a class of low molecular weight phenolic compounds that is widely distributed in the plant kingdom. They exhibit a diverse spectrum of biological functions and play an important role in the interaction between plants and their environment. Flavonoids not only protect the plant from the harmful effects of UV irradiation but also play a crucial role in the sexual reproduction process. A special class of flavonoid polymers, the tannins, plays a structural role in the plant. Yet other classes (...) of flavonoids, flavonols and anthocyanins, have been implicated in the attraction of pollinators. Certain flavonoids participate in the interaction between plants and other organisms such as symbiotic bacteria and parasites. This raises the intriguing question as to how these different compounds arose and evolved. Based on taxonomy and molecular analysis of gene expression patterns it is possible to deduce a putative sequence of acquisition of the different branches of the biosynthetic pathway and their regulators. (shrink)

In this study, we sought to assess the predictors of outcome in patients with disorders of consciousness (DOC) after severe traumatic brain injury (TBI) during neurorehabilitation stay. In total, 96 patients with DOC (vegetative state, minimally conscious state, or emergence from minimally conscious state) were enrolled (69 males; mean age 43.6 ± 20.8 years) and the improvement of the degree of disability, as assessed by the Disability Rating Scale, was considered the main outcome measure. To define the best predictor, a (...) series of demographical and clinical factors were modeled using a twofold approach: (1) logistic regression to evaluate a possible causal effect among variables; and (2) machine learning algorithms (ML), to define the best predictive model. Univariate analysis demonstrated that disability in DOC patients statistically decreased at the discharge with respect to admission. Genitourinary was the most frequent medical complication (MC) emerging during the neurorehabilitation period. The logistic model revealed that the total amount of MCs is a risk factor for lack of functional improvement. ML discloses that the most important prognostic factors are the respiratory and hepatic complications together with the presence of the upper gastrointestinal comorbidities. Our study provides new evidence on the most adverse short-term factors predicting a functional recovery in DOC patients after severe TBI. The occurrence of medical complications during neurorehabilitation stay should be considered to avoid poor outcomes. (shrink)