I have been anxious to improve the nick of time... to stand on the meeting of two eternities, the past and future, which is precisely the present moment; to toe that line.It is never too late to give up our prejudices.Inspired by Thoreau’s Walden and Other Writings, these epigraphs speak to the bridging potential I see in literature and art.1 Literature can link global issues of the day to human struggles that are anything but new, narratively fusing the past and (...) future together, helping the present to appear. When I make reference to aesthetic works in my classes, I am striving with my students to “improve the nick of time... [and] toe that line” of the present moment right there in the classroom. But what... (shrink)

In his Symphony n. 94 (1792), Haydn has a movement entitled “mit einem Paukenschlag,” which surprises the audience with a fortissimo timpani strike. This symphony, thus nicknamed “Die Überraschung,” offers a nice artistic example of fulguration against the background of imminence. Works of art offer a snapshot that unites beauty and novelty and evoke in us - in the artist as much as in the lover of music - the feeling of losing all control in a fraction of a second: (...) I call it the art of release [_déprise_]. The aim of my paper is to show the complexity of the emotional dynamic while identifying under the expression of “antinomic emotion,” and to dismantle thereby the current and naive understanding of emotions as being merely “uni-valent” (love is positive, hate is negative) or even as being “ambiguous” or “ambivalent” (e.g., the pleasure I have to see somebody suffer). With “antinomic emotions,” of which I will give and describe three main exemplary situations, there remains an open tension between opposed moves, like in the case of a painful joy (Diadochos of Photicea), of a dreadful beauty (Plato) or in the case of a drunken soberness (Gregorius of Nyssa). Such expressions have the particularity not to be immediately and obviously understandable, which is the heart of their interest and complexity and will precisely require the analysis that follows in the article. In order to reach the threshold of experiential emotional complexity, I will benefit from useful philosophical and phenomenological resources in Kant and his binary distinctive analysis of the feelings of beauty and sublime, in Max Scheler in his fine experiential distinctions between positive and negative empathy and his descriptions of pathological ambiguous emotions (e.g., the pleasure to see someone suffer), but also in some less well-known Husserl’s about intense emotional movements combining for example in multifarious microphase-time taste, disgust, and euphoria. We will show how such analyses are at the same time useful as thresholds of understanding and limited in their descriptive potentiality. To open up the discussion, I will state that the structure of open tension inherent in antinomic emotions is complemented by a specific dynamic of reversal of the opposed emotional polarities, which can take the form either of inversion or of annulment. (shrink)

As words, images, and concepts are the media through which hermeneutic understanding takes place, reflection on their nature is central to any appreciation of how hermeneutics operates. The joy of coming to recognition entails the knowing of something again that we already know as if for the first time. In the image, what we already know (pre‐reflectively) emerges as if illuminated, from all the contingent and variable circumstances that condition it; it is grasped in its essence. It is known as (...) something”. The speculative dimension of language elucidates the capacity of an image to be future orientated. Words, images, and concepts have actual and potential satellite meanings able to upset and transform their core meanings. Indeterminacy of meaning is central. Reading, writing, and attentive looking are practices which because of the speculative dimensions of word, image, and concept disturb and disrupt what we think we know with certainty. (shrink)

Searches for the sources and means for a disciplined practical approach to exploring human experience.

Natalie Stoljar ist eine australische Philosophin und Professorin für feministische, politische und Rechtsphilosophie an der McGill University in Montreal, Kanada. Neben der Forschung zur Rechtsphilosophie widmete sich Stoljar den Schnittstellen von Sozialphilosophie, politischer Philosophie und Moralpsychologie. In diesem Kontext verortet sie auch das Konzept der Autonomie.

Can we acquire apriori knowledge of mathematical facts from the outputs of computer programs? People like Burge have argued (correctly in our opinion) that, for example, Appel and Haken acquired apriori knowledge of the Four Color Theorem from their computer program insofar as their program simply automated human forms of mathematical reasoning. However, unlike such programs, we argue that the opacity of modern LLMs and DNNs creates obstacles in obtaining apriori mathematical knowledge from them in similar ways. We claim though (...) that if a proof-checker automating human forms of proof-checking is attached to such machines, then we can obtain apriori mathematical knowledge from them after all, even though the original machines are entirely opaque to us and the proofs they output may not, themselves, be human-surveyable. (shrink)

Ambitious targets to reduce greenhouse gas emissions from agriculture have been set by both national governments and their respective livestock sectors. We hypothesize that farmer self-identity influences their assessment of climate change and their willingness to implement measures which address the issue. Perceptions of climate change were determined from 286 beef/sheep farmers and evaluated using principal component analysis. The analysis elicits two components which evaluate identity, and two components which evaluate behavioral capacity to adopt mitigation and adaptation measures. Subsequent Cluster (...) Analyses reveal four farmer types based on the PCA scores. ‘The Productivist’ and ‘The Countryside Steward’ portray low levels of awareness of climate change, but differ in their motivation to adopt pro-environmental behavior. Conversely, both ‘The Environmentalist’ and ‘The Dejected’ score higher in their awareness of the issue. In addition, ‘The Dejected’ holds a high sense of perceived risk; however, their awareness is not conflated with an explicit understanding of agricultural GHG sources. With the exception of ‘The Environmentalist’, there is an evident disconnect between perceptions of agricultural emission sources and their contribution towards GHG emissions amongst all types. If such linkages are not conceptualized, it is unlikely that behavioral capacities will be realized. Effective communication channels which encourage action should target farmers based on the groupings depicted. Therefore, understanding farmer types through the constructs used in this study can facilitate effective and tailored policy development and implementation. (shrink)

Rapid Ethical Assessment (REA) is a form of rapid ethnographic assessment conducted at the beginning of research project to guide the consent process with the objective of reconciling universal ethical guidance with specific research contexts. The current study is conducted to assess the perceived relevance of introducing REA as a mainstream tool in Ethiopia.

In the literature of collective intentions, the ‘we-intentions’ that lie behind cooperative actions are analysed in terms of individual mental states. The core forms of these analyses imply that all Nash equilibrium behaviour is the result of collective intentions, even though not all Nash equilibria are cooperative actions. Unsatisfactorily, the latter cases have to be excluded either by stipulation or by the addition of further, problematic conditions. We contend that the cooperative aspect of collective intentions is not a property of (...) the intentions themselves, but of the mode of reasoning by which they are formed. We analyse collective intentions as the outcome of team reasoning, a mode of practical reasoning used by individuals as members of groups. We describe this mode of reasoning in terms of formal schemata, discuss a range of possible accounts of group agency, and show how existing theories of collective intentions fit into this framework. (shrink)

The upper time limit on growing embryos in culture for research could be revised, following a new recommendation by the Human Fertilisation and Embryology Authority (HFEA), the regulator of embryo research and fertility treatments in the UK. The recommendation was agreed at a meeting of the HFEA Authority, as part of wider discussions about modernising fertility law in the UK.1 Under the Human Fertilisation and Embryology Act 1990 (as amended), embryos which have been donated or created for research may be (...) grown in culture for up to 14 days or until the appearance of the primitive streak (whichever occurs sooner).2 This rule is widely replicated in other jurisdictions which permit the use of embryos in research.3 When this rule was adopted nearly 35 years ago, there was no prospect of sustaining embryos in vitro for more than a few days, and until recently, it has not posed a significant barrier to research.4 However, pressure to review the limit has grown following the publication of two studies in 2016 which demonstrated the technical feasibility of growing embryos to and potentially beyond the 14-day-limit.5 6 Proponents of changing the limit point to possible benefits of allowing …. (shrink)

Following the well-publicised case of Dr Sarah Benn, the former General Practioner (GP) who was suspended from the UK medical register earlier this year for breaching injunctions in order to peacefully protest climate change,1 uncertainty and wider discourse has persisted about the extent to which doctors can be involved in protests without risking regulatory action. In response to this uncertainty, in July the General Medical Council (GMC) published an explanation of how it manages concerns about doctors’ actions as part of (...) protests and activism. It includes the statement that they are bound by law to refer any conviction resulting in a custodial sentence directly to a Medical Practioners Tribunal Service (MPTS) hearing.2 They also state that the nature of the protest does not impact their consideration of whether there was a serious breach of professional standards or a risk to public protection.2 The move to clarify the GMC’s position has been cautiously welcomed by the UK Health Alliance on Climate Change but with criticisms that important questions remain unanswered, such as the GMC’s rationale for determining that public confidence in doctors is harmed by convictions arising from environmental activism.3 Interest in this issue shows little sign of fading, as regulatory action continues to be taken against climate activist doctors. Dr Diana Warner, a retired GP, was suspended from the medical register in August following a series of convictions for …. (shrink)

BackgroundOne of the next frontiers in HIV research is focused on finding a cure. A new priority includes people with HIV (PWH) with non-AIDS terminal illnesses who are willing to donate their bodies at the end-of-life (EOL) to advance the search towards an HIV cure. We endeavored to understand perceptions of this research and to identify ethical and practical considerations relevant to implementing it.MethodsWe conducted 20 in-depth interviews and 3 virtual focus groups among four types of key stakeholders in the (...) United States (PWH, biomedical HIV cure researchers, HIV clinicians, and bioethicists) to obtain triangulated viewpoints because little was known about the ethics of this topic. Each group was queried as to ethical considerations, safeguards, and protections for conducting HIV cure-related research at the EOL to ensure this research remains acceptable.ResultsAll four key stakeholder groups generally supported HIV cure-related research conducted at the EOL because of the history of altruism within the PWH community and the potential for substantial scientific knowledge to be gained. Our informants expressed that: (1) Strong stakeholder and community involvement are integral to the ethical and effective implementation, as well as the social acceptability of this research; (2) PWH approaching the EOL should not inherently be considered a vulnerable class and their autonomy must be respected when choosing to participate in HIV cure-related research at the EOL; (3) Greater diversity among study participants, as well as multi-disciplinary research teams, is necessitated by HIV cure-related research at the EOL; (4) The sensitive nature of this research warrants robust oversight to ensure a favorable risk/benefit balance and to minimize the possibility of therapeutic misconception or undue influence; and (5) Research protocols should remain flexible to accommodate participants’ comfort and needs at the EOL.ConclusionBecause of the ethical issues presented by HIV cure-related research at the EOL, robust ethical safeguards are of utmost importance. The proposed ethical and practical considerations presented herein is a first step in determining the best way to maximize this research’s impact and social value. More much inquiry will need to be directed towards understanding context-specific and cultural considerations for implementing EOL HIV cure research in diverse settings. (shrink)

Recent research suggests that individuals with relatively weak global precedence (i.e., a smaller propensity to view visual stimuli in a configural manner) show a reduced face inversion effect (FIE). Coupled with such findings, a number of recent studies have demonstrated links between an advantage for feature-based processing and the presentation of traits associated with autism among the general population. The present study sought to bridge these findings by investigating whether a relationship exists between the possession of autism-associated traits (i.e., as (...) indicated by individuals’“autism quotient” [(AQ) and the size of the FIE. Participants completed an on-line study in which the AQ was measured prior to a standard face recognition task where half of the faces were inverted at test. The results confirmed that higher AQ levels were predictive of smaller FIEs. Implications for a common underlying factor relating to processing orientation are discussed. (shrink)

This paper reports the results of three studies using mood induction procedures (MIPs) designed to investigate the relationship between anxiety and disgust. Study 1 used guided imagery vignettes (i.e., asking participants to imagine themselves in a series of described situations) and music (Mayer, Allen, & Beauregard, 1995). Study 2 used video clips (Gross & Levenson, 1995). Study 3 used autobiographical recall and music (Blagden & Craske, 1996). In order to be as sure as possible that target moods were being induced, (...) and that manipulation checks provided good evidence of mood induction, Studies 1 and 2 measured six moods (anxiety, sadness, happiness, anger, disgust, and contempt) on visual analogue scales. In addition, Study 3 included two further mood measures: a 30-adjective rating scale measuring 10 emotions, the Differential Emotion Scale (DES; Izard, 1972) and a free label questionnaire, allowing participants to record how they feel without any prior imposed structure. Results from all three studies demonstrated that induced anxiety will produce increases in reported disgust, but there was no evidence for an effect of induced disgust on reported anxiety. These findings were independent of the type of MIP (guided imagery vignette and music, video clips, and autobiographical recall and music), and the type of dependent mood measure used (visual analogue scale, differential emotion scale or a free label questionnaire). The findings have important implications for the putative role of disgust in anxious psychopathologies, and suggest that if disgust does have a causal influence in some anxious psychopathologies, this influence is not mediated simply by experienced disgust facilitating experienced anxiety. (shrink)

Everyday ethics refers to those issues which have a sometimes unrecognized moral dimension and that arise regularly within healthcare and research. These issues are often contrasted to dramatic ethics issues (i.e. issues that have seemingly higher stakes such as those arising in acute care situations or with invasive or life-threatening interventions). Claims have been made that scholarly bioethics tends to focus on dramatic ethics to the detriment of everyday ethics discussions. However, empirical evidence showing this has been lacking. Our own (...) research investigating bioethics discussions in the Parkinson’s disease literature suggested this trend. Consequently, we decided to characterize the context and content of the Parkinson’s disease bioethics literature to empirically test the hypothesis that everyday ethics is under discussed. We conducted a broad literature search using the keywords “Parkinson’s disease” AND (“ethics” OR “bioethics”) and classified results inductively based on the context in which the bioethics discussion occurred. In line with our hypothesis and initial observations, we found that there is indeed a greater focus on dramatic ethics where topics such as deep brain stimulation and neuronal cell transplantations, dominated bioethics discussions. Given the potential utility of everyday ethics in improving healthcare and research, this mismatch in focus ought to be addressed. There is a clear need for further understanding and discussion of everyday ethical issues in scholarly bioethics. (shrink)

Sometimes we make a decision about an action we will undertake later and form an intention, but our judgment of what it is best to do undergoes a temporary shift when the time for action comes round. What makes it rational not to give in to temptation? Many contemporary solutions privilege diachronic rationality; in some “rational non-reconsideration” (RNR) accounts once the agent forms an intention, it is rational not to reconsider. This leads to other puzzles: how can someone be motivated (...) to follow a plan that is contrary to their current judgment? How can it be rational to form a plan to resist if we can predict that our judgment will shift? I show how these puzzles can be solved in a framework where there are multiple units of agency, distinguishing between the judgments of the timeslice and those of the person over time, and allowing that the timeslice can “self identify”, taking the person over time as the relevant unit of agency and doing intrapersonal team reasoning (with a different causal role for intentions than RNR accounts). On my account, resisting temptation is compatible with synchronic rationality, so synchronic and diachronic rationality are aligned. However, either resisting or succumbing to temptation can be instrumentally rational, depending on the unit of agency that is identified with. In order to show why we ought to resist temptation, we need to draw on a non-instrumental rationale. I sketch possible routes for doing this. (shrink)

This is a profound study of Aristotle's concept of phronesis, or practical wisdom. Carlo Natali critically reconsiders Aristotle's famous doctrine of contemplations, relating it to contemporary theories of the good life.

A framing effect occurs when an agent's choices are not invariant under changes in the way a decision problem is presented, e.g. changes in the way options are described (violation of description invariance) or preferences are elicited (violation of procedure invariance). Here we identify those rationality violations that underlie framing effects. We attribute to the agent a sequential decision process in which a “target” proposition and several “background” propositions are considered. We suggest that the agent exhibits a framing effect if (...) and only if two conditions are met. First, different presentations of the decision problem lead the agent to consider the propositions in a different order (the empirical condition). Second, different such “decision paths” lead to different decisions on the target proposition (the logical condition). The second condition holds when the agent's initial dispositions on the propositions are “implicitly inconsistent,” which may be caused by violations of “deductive closure.” Our account is consistent with some observations made by psychologists and provides a unified framework for explaining violations of description and procedure invariance. (shrink)

Game theory is central to modern understandings of how people deal with problems of coordination and cooperation. Yet, ironically, it cannot give a straightforward explanation of some of the simplest forms of human coordination and cooperation--most famously, that people can use the apparently arbitrary features of "focal points" to solve coordination problems, and that people sometimes cooperate in "prisoner's dilemmas." Addressing a wide readership of economists, sociologists, psychologists, and philosophers, Michael Bacharach here proposes a revision of game theory that resolves (...) these long-standing problems. In the classical tradition of game theory, Bacharach models human beings as rational actors, but he revises the standard definition of rationality to incorporate two major new ideas. He enlarges the model of a game so that it includes the ways agents describe to themselves their decision problems. And he allows the possibility that people reason as members of groups, each taking herself to have reason to perform her component of the combination of actions that best achieves the group's common goal. Bacharach shows that certain tendencies for individuals to engage in team reasoning are consistent with recent findings in social psychology and evolutionary biology. As the culmination of Bacharach's long-standing program of pathbreaking work on the foundations of game theory, this book has been eagerly awaited. Following Bacharach's premature death, Natalie Gold and Robert Sugden edited the unfinished work and added two substantial chapters that allow the book to be read as a coherent whole. (shrink)

The freedom of expression is ‘the great bulwark of liberty’ and a ‘cornerstone upon which the very existence of a democratic society rests.’ It constitutes one of the ‘basic conditions for [a democratic society’s] progress,’ encapsulating ideas that may even ‘offend, shock or disturb.’ In his Rhetoric, Aristotle argues that free speech is of paramount importance, particularly in the form of a ‘robust public discourse as a means to promote citizen awareness and vigilance.’ To this end, freedom of expression is (...) a central tenet of democratic checks and balances as it allows for an ‘informed consent of the governed.’ Despite the recognition of this freedom since classical times, and the repeated proclamations of support by a variety of institutions, such as the Council of Europe, what is demonstrated, hereinafter, is that the freedom of expression is in a state of severe recession (regardless of the ‘openness’ of a society). This has resulted from a set of interrelated challenges, namely, the stark demise of Internet freedom within the general ambit of a widening conceptualization of hate, and the systematic strategy of moderating ‘hateful’ content. Whilst these challenges are inextricably interconnected with the technological revolution of our times, the authors hold that the fragile positioning of the freedom of expression in the framework of the Council of Europe and, particularly, the approach adopted by the major regional human rights court of the world, the European Court of Human Rights (ECtHR), has facilitated the systematic erosion of the central agora of expression, namely, the Internet and its fora. It is argued that the current _status quo_, as described hereinafter, is marked by a corrosion of _parrhesia_ or free speech itself and, also, of _isigoria,_ namely, the equal right of all to free speech. In light of the above, and for purposes of extrapolating on the challenges to this fundamental freedom, this paper will commence with a normative assessment of the legitimacy and impact of restricting the freedom of expression, followed by an overview of its position in the Council of Europe, with a focus on the concept of hate. Further, and emanating from the ECtHR’S position in _Delfi v Estonia,_ on the liability of Internet intermediaries, it will conduct an analysis of the status of speech online, extrapolating on the issue of ‘hate speech’ and the horizontalization of responsibility _vis-à-vis_ content moderation through the structural juxtaposition of private, profit-making companies deciphering on issues of freedom of expression through, inter alia (yet increasingly) the use of Artificial Intelligence. (shrink)

On tente ici d’illustrer la justesse de la comparaison que fait Husserl entre la réduction phénoménologique et une conversion religieuse, en prenant l’exemple très spécifique de la prière orthodoxe du coeur, où l’on trouve aussi la double exigence essentielle de la phénoménologie, d’un retour soigneux à l’expérience pratique et d’une description précise de l’expérience. The attempt is made here to illustrate the justice of Husserl’s comparison between phenomenological reduction and religious conversion, by considering the very specific example of the orthodox (...) prayer of the heart, where one also finds the twofold essential requirement of phenomenology, of a careful return to practical experience and of a precise description of experience. (shrink)

Summary Marie Curie directed a research laboratory from 1906 to 1934. Several studies have already described its operation, as well as its importance in the field of radioactivity. This article hopes to show, not how the laboratory was unique, but rather how it was integrated into the French University movement at the start of the 20th century. The goal is to resituate the Curie laboratory in the context of the history of higher scientific education in France. This study presents a (...) global overview of all the researchers of the Curie laboratory before focusing in particular upon its female researchers. In fact, the strong presence of women in this laboratory has often been noted. Did Marie Curie favour applications from women? What were the criteria she used to select her collaborators? New sources and biographical research now allow us to highlight the women who spent time at the Curie laboratory. Where did they come from? What were their social and geographic origins? What future did they have after the laboratory? Were they, like their director, able to reconcile research career and family life? Through them we will question the still persistent image of the female researcher devoted to science. (shrink)

A distinguished international team of scholars under the editorship of Carlo Natali have collaborated to produce a systematic, chapter-by-chapter study of one of the most influential texts in the history of moral philosophy. The seventh book of Aristotle's Nicomachean Ethics discusses weakness of will in its first ten chapters, then turns in the last four chapters to pleasure and its relation to the supreme human good.

Feminist epistemologies hold that differences in the social locations of inquirers make for epistemic differences, for instance, in the sorts of things that inquirers are justified in believing. In this paper we situate this core idea in feminist epistemologies with respect to debates about social constructivism. We address three questions. First, are feminist epistemologies committed to a form of social constructivism about knowledge? Second, to what extent are they incompatible with traditional epistemological thinking? Third, do the answers to these questions (...) raise serious problems for feminist epistemologies? We argue that some versions of two of the main strands in feminist epistemology – feminist standpoint theory and feminist empiricism – are committed to a form of social constructivism, which requires certain departures from traditional epistemological thinking. But we argue that these departures are less problematic than one might think. Thus, (some) feminist epistemologies provide a plausible way of understanding how (some) knowledge might be socially constructed. (shrink)

The definitive account of Aristotle's life and school This definitive biography shows that Aristotle's philosophy is best understood on the basis of a firm knowledge of his life and of the school he founded. First published in Italian, and now translated, updated, and expanded for English readers, this concise chronological narrative is the most authoritative account of Aristotle's life and his Lyceum available in any language. Gathering, distilling, and analyzing all the evidence and previous scholarship, Carlo Natali, one of the (...) world's leading Aristotle scholars, provides a masterful synthesis that is accessible to students yet filled with evidence and original interpretations that specialists will find informative and provocative. Cutting through the controversy and confusion that have surrounded Aristotle's biography, Natali tells the story of Aristotle's eventful life and sheds new light on his role in the foundation of the Lyceum. Natali offers the most detailed and persuasive argument yet for the view that the school, an important institution of higher learning and scientific research, was designed to foster a new intellectual way of life among Aristotle's followers, helping them fulfill an aristocratic ideal of the best way to use the leisure they enjoyed. Drawing a wealth of connections between Aristotle's life and thinking, Natali demonstrates how the two are mutually illuminating. For this edition, ancient texts have been freshly translated on the basis of the most recent critical editions; indexes have been added, including a comprehensive index of sources and an index to previous scholarship; and scholarship that has appeared since the book's original publication has been incorporated. (shrink)

In this paper I make the case for a feminist hinge epistemology in three steps. My first step is to explain hinge epistemologies as contemporary epistemologies that take Wittgenstein’s work in On Certainty as their starting point. My second step is to make three criticisms of this literature as it currently stands. My third step is to introduce feminist epistemologies, which argue that social factors like race and gender affect what different people and groups justifiably believe, and argue that developing (...) a feminist hinge epistemology is both plausible and desirable. (shrink)

For the most part, attention occurs as a theme adjacent to much more topical and innovatingly operating acts: first, the intentional act, which represents a destitution of the abstract opposition between subject and object and which paves the way for a detailed analysis of our perceptive horizontal subjective life; second, the reductive act, specified in a psycho-phenomenological sense as a reflective conversion of the way I am looking at things; third, the genetic method understood as a genealogy of logic based (...) on our experiential affective pre-discursive world-life. In this respect, here are some of the leading questions of my investigation: What are the differences and the proximities between these methods and attentional activity? Why is the latter not put to the fore as a method? To what extent is this secondary part played by attention linked to the constitution of phenomenology as opposed to psychology (for which attention is a central theme), and what does it mean for the impossibility of phenomenology to freeing itself completely from psychology? (shrink)

Background: Moral distress is a complex phenomenon frequently experienced by critical care nurses. Ethical conflicts in this practice area are related to technological advancement, high intensity work environments, and end-of-life decisions. Objectives: An exploration of contemporary moral distress literature was undertaken to determine measurement, contributing factors, impact, and interventions. Review Methods: This state of the science review focused on moral distress research in critical care nursing from 2009 to 2015, and included 12 qualitative, 24 quantitative, and 6 mixed methods studies. (...) Results: Synthesis of the scientific literature revealed inconsistencies in measurement, conflicting findings of moral distress and nurse demographics, problems with the professional practice environment, difficulties with communication during end-of-life decisions, compromised nursing care as a consequence of moral distress, and few effective interventions. Conclusion: Providing compassionate care is a professional nursing value and an inability to meet this goal due to moral distress may have devastating effects on care quality. Further study of patient and family outcomes related to nurse moral distress is recommended. (shrink)

This article explores the role scientists at the National Cancer Institute, a US federal science agency, played in researching and testing vaccines against the human papillomavirus. Drawing upon archival sources and oral history interview data, I challenge narratives that attribute the design of HPV vaccines to profit motive. Instead, I show that the researchers who developed the technology attempted to construct ethical approaches to vaccine development based on the values that emerged from their situated environments of technological, organizational, and institutional (...) constraint. I argue that interpretations of “translational research” native to the NCI influenced these researchers’ efforts to design and test HPV vaccines. The organizational culture of translational research emerging in the NCI positioned intramural research as a countervailing and supplementary force to market-oriented translational research and development. Over time, NCI researchers’ conceptions of the Institute’s role allowed them to develop understandings of ethical HPV vaccine research as oriented toward addressing cervical cancer health disparities, especially in developing nations. NCI scientists’ understanding of their role in serving the public good through continued HPV vaccine innovation reflects the material and political economic environment they faced at different historical junctures that constrained the possibilities for innovation and ethical action. (shrink)

In this article it is proved the necessity of forming and monitoring the investment policy. The main task of investment policy's monitoring are the organization of continuous observation of the object of study, formation of informative indicators; assessment and analysis of the information received, forecasting development and providing recommendations to avoid or reduce adverse effects on the object of study. It is proved that a monitoring system should include investment and provide flexibility and adaptability tools. There is studied foreign experience (...) of monitoring investment climate and defined principles of monitoring systems in accordance with the concept of sustainable development for an effective system of monitoring investment policy. The system of investment policy's monitoring as is a set of multiple monitoring systems, the implementation of which will accelerate the implementation of sustainable development in the domestic financial system. (shrink)

In this paper I explore the relationship between social epistemology and relativism in the context of feminist epistemology. I do this by focusing on one particular branch of feminist epistemology - a branch known as standpoint theory - and investigating the connection between this view and epistemic relativism. I begin by defining both epistemic relativism and standpoint theory, and by briefly recounting the standard way that the connection between these two views is understood. The literature at the moment focuses on (...) an aspect of standpoint theory called the epistemic advantage thesis, and on an aspect of relativism which has been called equality. I then show that the connection between relativism and standpoint theory actually turns on a different aspect of standpoint theory, known as the standpoint thesis, and on an aspect of relativism which has been called non-neutrality. I argue that shifting our attention to these other aspects reveals that standpoint theory is clearly and unavoidably relativist, but that this isn’t a problem - standpoint theory can capture everything that it set out to, even on a relativist understanding of the view. (shrink)