1. EXPLICATING THE CONCEPT OF REFLECTION (under review) -/- To understand how ‘reflection’ is used, I consider ordinary, philosophical, and scientific discourse. I find that ‘reflection’ seems to refer to reasoning that is deliberate and conscious, but not necessarily self-conscious. Then I offer an empirical explication of reflection’s conscious and deliberate features. These explications not only help explain how reflection can be detected; they also distinguish reflection from nearby concepts such as ruminative and reformative reasoning. After this, I find that (...) reflection is not obviously limited to only practical or only theoretical reasoning. The chapter ends with reasons to prefer ‘unreflective’ and ‘reflective’ to dual process theorists’ labels about systems or types. -/- 2. BOUNDED REFLECTIVISM & EPISTEMIC IDENTITY (in Metaphilosophy) -/- Reflection features centrally in philosophy (e.g., Korsgaard, 1996; Rawls, 1971; Sosa, 1991) and psychology (e.g., Pennycook, 2018). Bounded reflectivism is an empirically adequate model of reflection that explains reflection’s capacity to either help or hinder reasoning—e.g., reflective equilibrium vs. reflective polarization (e.g., Kahan et al., 2017). One innovation of the model is epistemic identity: an identity that involves particular beliefs—e.g., religious and political identities. When we feel that our epistemic identity is threatened, we can reflectively defend its beliefs rather than update our beliefs according to the best arguments and evidence. The solution, I argue, is not to suppress epistemic identity but embrace it by appealing to shared, superordinate epistemic identities. -/- 3. ALL MEASURES ARE NOT CREATED EQUAL (under review) -/- A bat and a ball cost $1.10 in total. The bat costs $1.00 more than the ball. How much does the ball cost? “10 cents” comes to most people’s minds immediately. However, upon reflection, we can realize that “5 cents” is the correct answer. There are many reflection tests. Each has its limitations. Some reflection tests are mathematical—like the bat-and-ball problem (e.g., Frederick, 2005) and others are logical (e.g., Janis & Frick, 1943). So there are concerns that reflection tests track logical and mathematical competence rather than reflection per se. Also, some psychologists assume a priori that correct answers are reflective and lured answers are unreflective. New evidence raises additional concerns about the plausibility of these assumptions. I argue that think aloud protocols (Ericsson & Simon, 1998) and process dissociation (Jacoby, 1991) can assuage some of these concerns. -/- 4. GREAT MINDS DO NOT THINK ALIKE (in Review of Philosophy and Psychology) -/- Two large studies (N = 1299), one pre-registered, found that many correlations between reflection and philosophical beliefs among non-philosophers replicated among philosophers. For example, less reflective philosophers preferred theism to atheism and utilitarian rather than deontological responses to the trolley problem (Hannikainen & Cova, in prep.; Pennycook et al., 2016; Reynolds, Byrd, & Conway, forthcoming). However, philosophical judgments were sometimes better predicted by factors like education, gender, and personality than by reflection test performance. So although some relationships between reflection and philosophy were robust, there is more to the link between reflection and philosophy. Normative implications are also discussed—e.g., how we can infer the quality of philosophical views from their correlations with reflective or unreflective reasoning. -/- 5. WHAT WE CAN (AND CAN’T) INFER ABOUT IMPLICIT BIAS (in Synthese) -/- Contrary to some philosophers and psychologists, I argue that implicit bias is probably associative. However, I also argue that debiasing is not thereby entirely unconscious and involuntary. Indeed, strong evidence suggests that reflection can change implicitly biased behavior—e.g., conscious and deliberate counterconditioning. This has implications for the science and morality of implicit bias—e.g., evidence suggests that we can reform biases; so. intuitively, we can be responsible for biases. (shrink)

Epistemologists spend a great deal of time thinking about how we should respond to our evidence. They spend far less time thinking about the ways that evidence can be acquired in the first place. This is an oversight. Some ways of acquiring evidence are better than others. Many normative epistemologies struggle to accommodate this fact. In this article I develop one that can and does. I identify a phenomenon – epistemic feedback loops – in which evidence acquisition has gone awry, (...) with the result that even beliefs based on the evidence are irrational. Examples include evidence acquired under the influence of confirmation bias and evidence acquired under the influence of cognitively penetrated experiences caused by implicit bias. I then develop a theoretical framework which enables us to understand why beliefs that are the outputs of epistemic feedback loops are irrational. Finally, I argue that many popular approaches to epistemic normativity may need to be abandoned on the grounds that they cannot comfortably explain feedback loops. The scope of this last claim is broad: it includes almost all contemporary theories of justified/rational belief and of the epistemology of cognitive penetration. (shrink)

An influential line of thinking in behavioral science, to which the two authors have long subscribed, is that many of society's most pressing problems can be addressed cheaply and effectively at the level of the individual, without modifying the system in which the individual operates. We now believe this was a mistake, along with, we suspect, many colleagues in both the academic and policy communities. Results from such interventions have been disappointingly modest. But more importantly, they have guided many (though (...) by no means all) behavioral scientists to frame policy problems in individual, not systemic, terms: To adopt what we call the “i-frame,” rather than the “s-frame.” The difference may be more consequential than i-frame advocates have realized, by deflecting attention and support away from s-frame policies. Indeed, highlighting the i-frame is a long-established objective of corporate opponents of concerted systemic action such as regulation and taxation. We illustrate our argument briefly for six policy problems, and in depth with the examples of climate change, obesity, retirement savings, and pollution from plastic waste. We argue that the most important way in which behavioral scientists can contribute to public policy is by employing their skills to develop and implement value-creating system-level change. (shrink)

Conventional sacrificial moral dilemmas propose directly causing some harm to prevent greater harm. Theory suggests that accepting such actions (consistent with utilitarian philosophy) involves more reflective reasoning than rejecting such actions (consistent with deontological philosophy). However, past findings do not always replicate, confound different kinds of reflection, and employ conventional sacrificial dilemmas that treat utilitarian and deontological considerations as opposite. In two studies, we examined whether past findings would replicate when employing process dissociation to assess deontological and utilitarian inclinations independently. (...) Findings suggested two categorically different impacts of reflection: measures of arithmetic reflection, such as the Cognitive Reflection Test, predicted only utilitarian, not deontological, response tendencies. However, measures of logical reflection, such as performance on logical syllogisms, positively predicted both utilitarian and deontological tendencies. These studies replicate some findings, clarify others, and reveal opportunity for additional nuance in dual process theorist’s claims about the link between reflection and dilemma judgments. (shrink)

What are the sensory individuals of audition? What are the entities our auditory system attributes properties to? We examine various proposals about the nature of the sensory individuals of audition, and show that while each can account for some aspects of auditory perception, each also faces certain difficulties. We then put forward a new conception of sensory individuals according to which auditory sensory individuals are composite individuals. A feature shared by all existing accounts of sounds and sources is that they (...) postulate sensory individuals that are non-composite. They identify the sensory individual of sound hearing or source hearing with one type of entity in the environment, be they sound waves, vibrations, or interactions. We question this assumption and argue that our perceptual systems represent two or more aspects of the environment as a single sensory individual. Finally, we show that taking auditory individuals to be composite sensory individuals allows for an account of audition that is less problematic than its existing alternatives. (shrink)

Human enhancement has emerged in recent years as a blossoming topic in applied ethics. With continuing advances in science and technology, people are beginning to realize that some of the basic parameters of the human condition might be changed in the future. One important way in which the human condition could be changed is through the enhancement of basic human capacities. If this becomes feasible within the lifespan of many people alive today, then it is important now to consider the (...) normative questions raised by such prospects. The answers to these questions might not only help us be better prepared when technology catches up with imagination, but they may be relevant to many decisions we make today, such as decisions about how much funding to give to various kinds of research. Enhancement is typically contraposed to therapy. In broad terms, therapy aims to fix something that has gone wrong, by curing specific diseases or injuries, while enhancement interventions aim to improve the state of an organism beyond its normal healthy state. However, the distinction between therapy and enhancement is problematic, for several reasons. First, we may note that the therapy-enhancement dichotomy does not map onto any corresponding dichotomy between standard-contemporary-medicine and medicineas-it-could-be-practised-in-the-future. Standard contemporary medicine includes many practices that do not aim to cure diseases or injuries. It includes, for example, preventive medicine, palliative care, obstetrics, sports medicine, plastic surgery, contraceptive devices, fertility treatments, cosmetic dental procedures, and much else. At the same time, many enhancement interventions occur outside of the medical framework. Office workers enhance their performance by drinking coffee. Make-up and grooming are used to enhance appearance. Exercise, meditation, fish oil, and St John’s Wort are used to enhance mood. Second, it is unclear how to classify interventions that reduce the probability of disease and death.. (shrink)

A version of relationism that takes spatiotemporal structures—spatial geometry and a standard of inertia—to supervene on the history of relations between bodies is described and defended. The account is used to explain how the relationist should construe models of Newtonian mechanics in which absolute acceleration manifestly does not supervene on the relations; Ptolemaic and Copernican models for example. The account introduces a new way in which a Lewis-style ‘best system’ might capture regularities in a broadly Humean world; a defence is (...) given against a charge of indeterminism that applies to any such approach to laws. (shrink)

I argue against inferentialism about logic. First, I argue against an analogy between logic and chess, before considering a more basic objection to stipulating inference rules as a way of establishing the meaning of logical constants. The objectionthe Mushroom Omelette Objectionis that stipulative acts are partly constituted by logical notions, and therefore cannot be used to explain logical thought. I then argue that the same problem also attaches to following existing conventional rules, since either those rules have logical contents, or (...) following those conventional rules is done for logical reasons. Lastly, I compare this argument with other arguments found in Quine’s early work, and consider two attempts to reply to Quine. (shrink)

I describe and defend the view in a philosophy of mind that I call 'Normative Essentialism', according to which propositional attitudes have normative essences. Those normative essences are 'horizontal' rational requirements, by which I mean the requirement to have certain propositional attitudes given other propositional attitudes. Different propositional attitudes impose different horizontal rational requirements. I distinguish a stronger and a weaker version of this doctrine and argue for the weaker version. I explore the consequences for knowledge of mind, and I (...) then consider objections to the view from mental causation, from empirical psychology, and from animals and small children. (shrink)

This paper argues that the dirty hands literature has overlooked a crucial distinction in neglecting to discuss explicitly the issue of, what I call, symmetry. This is the question of whether, once we are confronted with a dirty hands situation, we could emerge with our hands clean depending on the action we choose. A position that argues that we can keep our hands clean I call “asymmetrical” and one that says that we will get our hands dirty no matter what (...) we do I call “symmetrical”. Not acknowledging this distinction is a problem because, firstly, it adds to the existing confusions about how best to define what dirty hands are. Secondly, it prevents the concept of dirty hands from being applied properly to other contexts such as, for example, the responsibility and accountability of politicians. I argue that we have good reason to favour a symmetrical understanding because it gives a more convincing account of what makes an action dirty and because it more accurately captures our complex moral decision-making when faced with dirty hands situations. The paper concludes by outlining possible implications that the distinction between the symmetry view and the asymmetry view has on wider debates surrounding the problem of dirty hands. (shrink)

In this paper, we explore and describe what is needed to allow connected and automated vehicles to break traffic rules in order to minimise road safety risk and to operate with appropriate transparency. Reviewing current traffic rules with particular reference to two driving situations, we illustrate why current traffic rules are not suitable for CAVs and why making new traffic rules specifically for CAVs would be inappropriate. In defining an alternative approach to achieving safe CAV driving behaviours, we describe the (...) use of ethical goal functions as part of hybrid AI systems, suggesting that functions should be defined by governmental bodies with input from citizens and stakeholders. Ethical goal functions for CAVs would enable developers to optimise driving behaviours for safety under conditions of uncertainty whilst allowing for differentiation of products according to brand values. Such functions can differ between regions according to preferences for safety behaviours within that region and can be updated over time, responding to continual socio-technological feedback loops. We conclude that defining ethical goal functions is an urgent and necessary step from governmental bodies to enable the safe and transparent operation of CAVs and accelerate the reduction in road casualties they promise to achieve. (shrink)

Could spacetime be derived rather than fundamental? The question is pressing because attempts to quantize gravity have led to theories in which (arguably) there are either no, or only extremely thin, spacetime structures. Moreover, recent proposals for the interpretation of quantum mechanics have suggested that 3-dimensional space may be an ‘appearance’ derived from the 3N-dimensional space in which an N-particle wavefunction lives (cross- reference). In fact, I will largely assume a positive answer, and investigate how it could be; in particular, (...) I want to explicate the role of philosophy in producing a satisfactory explanation of spacetime, providing a roadmap for philosophical engagement with quantum gravity. (shrink)

This paper is about an anti-expertise paradox that arises because of self-referential sentences like: = I do not believe that is true. The first aim is to motivate, develop, and defend a novel view of epistemic rationality according to which there can be genuine rational indeterminacy, i.e., it can be indeterminate which doxastic states an agent is rationally permitted or required to have. The second aim is to show how this view can provide a solution to this paradox while also (...) avoiding the problems that plague its rivals. (shrink)

In this paper we seek to examine the quest for a better way of life through migration, known as lifestyle migration, by positioning place as the a priori condition through which this experience happens. Following the work of Malpas, we argue that lifestyle migration literature has often positioned place in the background, failing to notice how an individual’s style of life is enacted through place and because of it. In order to understand the lifestyle in these migrations, place must be (...) taken seriously as a grounding theoretical and empirical topic for investigation. Using a topographical approach, we propose using the metaphorical concept of ‘survey marks’ which are designed to understand the different components of place which make up the whole. We set out three of these in our interrogation of empirical research of lifestyle migrants in Tasmania and on the Sunshine Coast in Australia to illustrate the importance of place in this research. (shrink)

The problem of dirty hands is, roughly speaking, concerned with situations in which an agent is faced with a choice between two evils so that, no matter what they do, they will have to violate something of important moral value. Theorists have been primarily concerned with dirty hands choices arising in politics because they are thought to be particularly frequent and pressing in this sphere. Much of the subsequent discussion in the literature has focused on the impact that such choices (...) have on a well-functioning democracy and how, if at all, we can ensure that a politician dirtying their hands does not undermine core democratic values and processes. A particular concern has been whether dirty-handed politicians ought to publicly reveal their actions after the fact and whether they should be held accountable through some form of punishment. The first aim of this paper is to point out that the focus on what is required in the wake of a dirty-handed decision, based on the need to protect the democratic system ought to be balanced with a genuine concern for reparative justice and what is owed to the victims of dirty hands. In the second part of this paper, I then examine the suitability of one common way in which perpetrators partly repair the damage they have done to victims, namely apologizing, in the dirty hands context. (shrink)

Recently, many historians of science have chosen to present their historical narratives from the ‘actors’-eye view’. Scientific knowledge not available within the actors’ culture is not permitted to do explanatory work. Proponents of the Sociology of Scientific Knowledge purport to ground this historiography on epistemological relativism. I argue that they are making an unnecessary mistake: unnecessary because the historiographical genre in question can be defended on aesthetic and didactic grounds; and a mistake because the argument from relativism is in any (...) case incoherent.The argument of the present article is self-contained, but steers clear of metaphysical debates in the philosophy of science. To allay fears of hidden assumptions, the sequel, to be published in the following issue, will consider SSK’s prospects of succour from scientific realism, instrumentalism, and a metaphysical system of Bruno Latour’s own devising. (shrink)

I discuss a model inspired from the string/brane framework, in which our Universe is represented (after perhaps appropriate compactification) as a three brane, propagating in a bulk space time punctured by D0-brane (D-particle) defects. As the D3-brane world moves in the bulk, the D-particles cross it, and from an effective observer on D3 the situation looks like a “space-time foam” with the defects “flashing” on and off (“D-particle foam”). The open strings, with their ends attached on the brane, which represent (...) matter in this scenario, can interact with the D-particles on the D3-brane universe in a topologically non-trivial manner, involving splitting and capture of the strings by the D0-brane defects. Such processes are consistently described by logarithmic conformal field theories on the world-sheet of the strings. Physically, they result in effective decoherence of the string matter on the D3 brane, and as a result, of CPT Violation, but of a type that implies an ill-defined nature of the effective CPT operator. Due to electric charge conservation, only electrically neutral (string) matter can exhibit such interactions with the D-particle foam. This may have unique, experimentally detectable (in principle), consequences for electrically-neutral entangled quantum matter states on the brane world, in particular the modification of the pertinent Einstein-Podolsky-Rosen (EPR) Correlation in neutral mesons in an appropriate meson factory. For the simplest scenarios, the order of magnitude of such effects might lie within the sensitivity of upgraded φ-meson factories. (shrink)

Most of the debate for and against aesthetic formalism in the twentieth century has been little more than a sequence of assertions, on both sides. But there is one discussion that stands out for its argumentative subtlety and depth, and that is Kendall Walton’s paper ‘Categories of Art’.1 In what follows I shall defend a certain version of formalism against the antiformalist arguments which Walton deploys. I want to show that while Walton’s arguments do indeed create insurmountable difficulties for an (...) extreme version of formalism, he has not shown that a moderate version is problematic or inadequate. (I have no space to address anti-formalist arguments other than Walton’s.2) I shall defend moderate formalism rather than put forward positive considerations in its favour, although some of its attractions will become apparent as a side-effect. I pursue the positive case for moderate formalism elsewhere.3 I. FORMAL PROPERTIES AND FORMALISMS I.1. Walton begins his paper by raising an issue about whether those who make aesthetic judgements should only be concerned with what can be directly perceived in works of art. The issue of formalism has often been described in these terms. But Walton rightly distances himself from setting up a debate in that way. He moves on to take as his target the view that ‘Circumstances connected with a work’s origin ... have no essential bearing on an assessment of its aesthetic nature’ (p. 334). (shrink)

A collection of essays discussing the philosophy and foundations of quantum gravity. Written by leading philosophers and physicists in the field, chapters cover the important conceptual questions in the search for a quantum theory of gravity, and the current state of understanding among philosophers and physicists.

Evidence based-policy (EBP) is a popular research paradigm in the applied social sciences and within government agencies. Informally, EBP represents an explicit commitment to applying scientific methods to public affairs, in contrast to ideologically-driven or merely intuitive “common-sense” approaches to public policy. More specifically, the EBP paradigm places great weight on the results of experimental research designs, especially randomised controlled trials (RCTs), and systematic literature reviews that place evidential weight on experimental results. One hope is that such research designs and (...) approaches to analysing the scientific literature are sufficiently robust that they can settle what really ‘works’ in public policy. Can EBP succeed in displacing reliance on domain-specific expertise? On our account, this is seldom, if ever, the case. The key reason for this is that underlying this approach is generally an appeal to argument by induction, which always requires further assumptions to underwrite its validity, and if not induction, some other argument form that also requires assumptions that are very often not validated for the case at hand. (shrink)

Responding to serious environmental problems, requires urgent and fundamental shifts in our day-to-day lifestyles. This paper employs a qualitative, cross-cultural approach to explore people’s subjective self-reflections on their experiences of pro-environmental behavioral spillover in three countries; Brazil, China, and Denmark. Behavioral spillover is an appealing yet elusive phenomenon, but offers a potential way of encouraging wider, voluntary lifestyle shifts beyond the scope of single behavior change interventions. Behavioral spillover theory proposes that engaging in one pro-environmental action can catalyze the performance (...) of others. To date, evidence for the phenomenon has been mixed, and the causal processes governing relationships between behaviors appear complex, inconsistent and only partly understood. This paper addresses a gap in the literature by investigating accounts of behavioral spillover in three diverse cultural settings using qualitative semi-structured interviews. The analysis shows that while around half of participants overall who were questioned recalled spillover effects, the other half had not consciously experienced spillover. There were few significant differences across cultures, though some forms of spillover effects were reported more in some cultures than others. More environmentally-engaged participants across all three countries were significantly more likely to experience spillover than those who were less engaged. Accounts of within-domain spillovers were most commonly reported, mainly comprising waste, resource conservation and consumption-related actions. Accounts of between-domain spillover were very rare. Recollection of contextual and interpersonal spillover effects also emerged from the interviews. Our findings suggest that more conscious behavioral spillover pathways may be limited to those with pre-existing environmental values. Behavioral spillover may comprise multiple pathways incorporating conscious and unconscious processes. We conclude that targeting behavioral catalysts that generate more socially diffuse spillover effects could offer more potential than conventional spillover involving a single individual. (shrink)

There has been considerable recent philosophical debate over the implications of many particle quantum mechanics for the metaphysics of individuality (cf. Huggett [1997]). In this paper I look at things from a rather different perspective: by investigating the significance of permutation symmetry. I consider how various philosophical positions link up to the physical postulate of the indistinguishability of permuted states-permutation invariance-and how this postulate is used to explain quantum statistics. I offer an explanation of the statistics that relies on the (...) neglected parallel between permutations and covariant spatial transformation. And I explore the parallel, showing that a further kind of symmetry explains why permutations are invariant when spatial symmetries are not. (shrink)

John Leslie presents a thought experiment to show that chances are sometimes observer-relative in a paradoxical way. The pivotal assumption in his argument – a version of the weak anthropic principle – is the same as the one used to get the disturbing Doomsday argument off the ground. I show that Leslie's thought experiment trades on the sense/reference ambiguity and is fallacious. I then describe a related case where chances are observer-relative in an interesting way. But not in a paradoxical (...) way. The result can be generalized: At least for a very wide range of cases, the weak anthropic principle does not giverise to paradoxical observer-relative chances. This finding could be taken to give new indirect support to the doomsday argument. (shrink)

Historians of science have frequently sought to exclude modern scientific knowledge from their narratives. Part I of this paper, published in the previous issue, cautioned against seeing more than a literary preference at work here. In particular, it was argued—contra advocates of the Sociology of Scientific Knowledge —that a commitment to epistemological relativism should not be seen as having straightforward historiographical consequences. Part II considers further SSK-inspired attempts to entangle the currently fashionable historiography with particular positions in the philosophy of (...) science. None, I argue, is promising. David Bloor’s proposed alliance with scientific realism relies upon a mistaken view of contrastive explanation; Andrew Pickering’s appeal to instrumentalism is persuasive for particle physics but much less so for science as a whole; and Bruno Latour’s home-grown metaphysics is so bizarre that its compatibility with SSK is, if anything, a further blow to the latter’s plausibility. (shrink)

Cognitive enhancement takes many and diverse forms. Various methods of cognitive enhancement have implications for the near future. At the same time, these technologies raise a range of ethical issues. For example, they interact with notions of authenticity, the good life, and the role of medicine in our lives. Present and anticipated methods for cognitive enhancement also create challenges for public policy and regulation.

riety of necessity that binds moral and natural his conception of mental properties has no metaphysical consequences. Descartes is properties because the necessity is neither..

This article offers five things: first, a description of the current status of aesthetics as a sub-discipline of philosophy, showing that it's currently not regarded as part of the field's core; second, a case history asserting that the particular interests and approaches of aestheticians active in the twenty years or so after 1945 started trends that have defined the sub-discipline ever since; third, a diagnosis arguing that this definition, which involves a narrow focus on certain questions about art, is responsible (...) for the marginal status of aesthetics, leading as it does to the estrangement of curious students and the devaluation of expertise in aesthetics; fourth, a prescription suggesting that we can reverse those trends, and so bring aesthetics toward the core of philosophy; and fifth, a prognosis demonstrating that, happily, just the approach prescribed is already starting to take hold in aesthetics. (shrink)

I defend extreme formalism about the aesthetics of inorganic nature. I outline the general issue over aesthetic formalism as it manifests itself in the visual arts. The main issue is over whether we need to know about the history of artworks in order to appreciate them aesthetically. I then turn to nature and concede that with organic nature we need to know a thing's biological kinds if we are fully to appreciate it. However, with in organic nature I deny that (...) we need to know the deeper nature of the things we experience. What is important, I argue, are the appearances of those things not their real natures. I consider the beauty of clouds, which depends on an illusion of solidity, and I argue that scientific knowledge does not reveal beauty that is not available to the ignoramous. There is only the beauty of appearances, and it does not matter whether those appearances are accurate or illusory. (shrink)

I explore the Because Constraint—the idea that moral facts depend on natural facts and that moral judgements ought to respect the dependence of moral facts on natural facts. I consider several issues concerning its clarification and importance.

I argue that people do not and cannot have religious experiences that are perceptual experiences with theological content and that provide some justification for the belief in God. I discuss William Alston's resourceful defence of this idea. My strategy is to say that religious perception would either have to be by means of one of the ordinary five senses or else by means of some special sixth religious sense. In either case insoluble epistemological problems arise. The problem is with perceiving (...) God as God, which we need to do if reasons to believe in God are to be generated. To do so, we would have to perceive the instantiation of His essential properties – being all-knowing, all-powerful, and all-good. But perceiving the instantiation of these properties of God, even by some special sixth religious sense, is impossible. Hence, God cannot be perceived either by the ordinary five senses or by a sixth religious sense. Religious perceptual experiences are a myth. (Published Online February 17 2004). (shrink)

Over the past 50 years, academic-industrial collaborations and technology transfer have played an increasingly prominent role in the biomedical sciences. These relationships can speed the delivery of innovative drugs and medical technologies to clinical practice, creating important public health benefits as well as income for universities and their faculty. At the same time, they raise ethical concerns, particularly when research involves human subjects in clinical trials. Lapses in oversight of industry sponsored clinical trials at universities, and especially patient deaths in (...) a number of trials, have brought these issues into the public spotlight and have led the federal government to intensify its oversight of clinical research. The leadership of Harvard Medical School convened a group of leaders in academic medicine to formulate guidelines on individual financial conflicts of interest. They and other groups are working to formulate a national consensus on this issue. (shrink)

Collagen is the most abundant vertebrate protein and forms a stable fibrous architecture in connective tissues, such as bone, cartilage, skin and tendon. Much recent research has been directed towards an understanding of the molecular and cellular mechanisms involved in the synthesis and degradation of collagen, because a change in the normal balance, or an increased destruction of collagen, can cause loss of function of specialized tissues. This short review attempts to summarize present knowledge about the proteolytic destruction of collagen (...) and the exciting new work on the factors that are emerging as important controlling agents. An understanding of the regulatory processes is yielding some important clues regarding the levels at which they can fail in pathological conditions and we speculate about evolving strategies for preventing uncontrolled resorption. (shrink)

Book reviewed in this article: Ethical Dilemmas and Social Science Research. By Paul Davidson Reynolds.

ABSTRACTIn ‘The Principles of Art’, R. G. Collingwood argues that art is the imaginative expression of emotion. So much the worse, then, for Collingwood. The theory seems hopelessly inadequate to the task of capturing art’s extension: of encompassing all the works we generally suppose should be rounded up under the concept. A great number of artworks, and several art forms, have nothing to do with emotion. But it would be surprising were Collingwood philistine enough to think that art is only (...) ever concerned with communicating quotidian affective states, like anger, fear or love. Surely he has some more sophisticated notion of emotion in mind, and quite probably of expression too. And it turns out that those sophisticated notions can be pushed towards a version of the expression theory that meets the extensional challenge. If we interpret Collingwood as saying that expression is a particular application of imagination, and that imagination is the faculty that refines ideas of emotions, and that ‘emotions’... (shrink)

God is thought of as hidden in at least two ways. Firstly, God's reasons for permitting evil, particularly instances of horrendous evil, are often thought to be inscrutable or beyond our ken. Secondly, and perhaps more problematically, God's very existence and love or concern for us is often thought to be hidden from us (or, at least, from many of us on many occasions). But if we assume, as seems most plausible, that God's reasons for permitting evil will (in many, (...) if not most, instances) be impossible for us to comprehend, would we not expect a loving God to at least make his existence or love sufficiently clear to us so that we would know that there is some good, albeit inscrutable, reason why we (or others) are permitted to suffer? In this paper I examine John Hick's influential response to this question, a response predicated on the notion of 'epistemic distance': God must remain epistemically distant and hence hidden from us so as to preserve our free will. Commentators of Hick's work, however, disagree as to whether the kind of free will that is thought to be made possible by epistemic distance is the freedom to believe that God exists, or the freedom to choose between good and evil, or the freedom to enter into a personal relationship with God. I argue that it is only the last of these three varieties of free will that Hick has in mind. But this kind of freedom, I go on to argue, does not necessitate an epistemically distant God, and so the problem of divine hiddenness remains unsolved.
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