In recent years, several countries have enacted guidelines and/or mandatory laws to increase the presence of women on the boards of companies. Through these regulatory interventions, the aim is to eradicate the social and labor grievances that women have traditionally experienced and which has relegated them to smaller-scale jobs. Nevertheless, and despite the advances achieved, the female representation in the boardroom remains far from the desired levels. In this context, it is now necessary to enhance the advantages of board gender (...) diversity from both ethical and economic points of view. This article examines the relation between board gender diversity and economic results in Spain: the second country in the world to legally require gender quotas in boardrooms and historically characterized by a minimal female participation in the workforce. Based on a sample of 125 non-financial firms listed on the Madrid Stock Exchange from 2005 to 2009, our findings show that in the period analyzed the increase of the number of women on boards was over 98 %. This suggests that compulsory legislation offers an efficient framework to execute the recommendation of Spanish codes of good governance by means of the increase in the number of women in the boards of firms. Furthermore, we find that the increase in the number of women on the boards is positively related to higher economic results. Therefore, both results suggest that gender diversity in boardrooms should be incremented, mandatory laws being a key factor to do so. (shrink)

Zusammenfassung In Körper schreiben sich Attraktivitätsnormen oder auch die Vorstellung der Verschiedenheit genau zweier Geschlechter ein - was ich hier als bodification verhandle. Auf der anderen Seite konzipiere ich beautification oder Schönheitshandeln als ein Medium der Kommunikation, das der Inszenierung der eigenen Außenwirkung zum Zweck der Erlangung von Aufmerksamkeit und Sicherung der eigenen Identität dient. In welcher Weise nun Bilder und Praxen des Schönheitshandelns mit Normalitätsvorstellungen verknüpft sind, wie diese hergestellt werden und auch unterlaufen werden können, ist Thema dieses Beitrags. (...) Dabei entwickle ich die These, dass nicht primär der Körperbezug und auch nicht das Geschlecht mit der Empfänglichkeit bzw. Resistenz gegenüber Ideologien und Naturalisierungen rund um Schönheitshandeln zu tun haben, sondern vielmehr der Bezug auf Sexualität, genauer: die offene und reflektierte Fähigkeit und Bereitschaft, über Sexualität zu sprechen. (shrink)

Many authors assume that Broca's area subserves the functions that are lost in patients with Broca's aphasia. This commentary attempts to clarify the relationship between Broca's area and Broca's aphasia and suggests that statements about the neurology of patients' specific language functions might be better supported by their individual structural neuroimaging data.

I argue against the common and influential view that non-trivial chances arise only when the fundamental laws are indeterministic. The problem with this view, I claim, is not that it conflicts with some antecedently plausible metaphysics of chance or that it fails to capture our everyday use of ‘chance’ and related terms, but rather that it is unstable. Any reason for adopting the position that non-trivial chances arise only when the fundamental laws are indeterministic is also a reason for adopting (...) a much stronger, and far less attractive, position. I suggest an alternative account, according to which chances are probabilities that play a certain explanatory role: they are probabilities that explain associated frequencies. 1 Introduction2 A Paradigm Case3 The Incompatibilist’s Criterion4 Against the Incompatibilist’s Criterion5 The Explanatory Criterion6 Conclusion. (shrink)

Next SectionWe discuss the thesis formulated by Hintikka (1973) that certain natural language sentences require non-linear quantification to express their meaning. We investigate sentences with combinations of quantifiers similar to Hintikka's examples and propose a novel alternative reading expressible by linear formulae. This interpretation is based on linguistic and logical observations. We report on our experiments showing that people tend to interpret sentences similar to Hintikka sentence in a way consistent with our interpretation.

The volume documents, and makes an original contribution to, an astonishing period in twentieth-century philosophy—the progress of Arne Naess's ecophilosophy from its inception to the present. It includes Naess's most crucial polemics with leading thinkers, drawn from sources as diverse as scholarly articles, correspondence, TV interviews and unpublished exchanges. The book testifies to the skeptical and self-correcting aspects of Naess's vision, which has deepened and broadened to include third world and feminist perspectives. Philosophical Dialogues is an essential addition to the (...) literature on environmental philosophy. (shrink)

Das Sterben wird längst nicht mehr verdrängt und verschwiegen, es gehört vielmehr zu den ausgiebig erörterten Themen unserer Zeit. Viele Debatten ranken sich um Sterbehilfe und um die Frage, was einen guten Tod ausmacht. Dabei scheinen wir uns bemerkenswert einig zu sein, dass gut stirbt, wer bis zuletzt er oder sie selbst bleibt. Wir wünschen uns, so die These dieses Buches, unseren 'eigenen Tod': ein Lebensende, wie es uns entspricht, ein authentisches Sterben. Dieses Ideal leitet in unterschiedlicher Weise die Palliativversorgung (...) und die Sterbehilfebewegung an. Doch Nina Streeck zeigt, dass sich das, was so erstrebenswert klingt, als anspruchsvoll entpuppt. Die Idee des 'eigenen Todes' droht sich in ihr Gegenteil zu verkehren: in einen Zwang zum authentischen Sterben."--Page 4 of cover. (shrink)

A long tradition of psychological research has explored the distinction between characteristics that are part of the self and those that lie outside of it. Recently, a surge of research has begun examining a further distinction. Even among characteristics that are internal to the self, people pick out a subset as belonging to the true self. These factors are judged as making people who they really are, deep down. In this paper, we introduce the concept of the true self and (...) identify features that distinguish people’s understanding of the true self from their understanding of the self more generally. In particular, we consider recent findings that the true self is perceived as positive and moral, and that this tendency is actor-observer invariant and cross-culturally stable. We then explore possible explanations for these findings and discuss their implications for a variety of issues in psychology. (shrink)

Relational reasoning is a hallmark of human higher cognition and creativity, yet it is notoriously difficult to encourage in abstract tasks, even in adults. Generally, young children initially focus more on objects, but with age become more focused on relations. While prerequisite knowledge and cognitive resource maturation partially explains this pattern, here we propose a new facet important for children's relational reasoning development: a general orientation to relational information, or a relational mindset. We demonstrate that a relational mindset can be (...) elicited, even in 4‐year‐old children, yielding greater than expected spontaneous attention to relations. Children either generated or listened to an experimenter state the relationships between objects in a set of formal analogy problems, and then in a second task, selected object or relational matches according to their preference. Children tended to make object mappings, but those who generated relations on the first task selected relational matches more often on the second task, signaling that relational attention is malleable even in young children. (shrink)

Carpendale & Lewis (C&L) provide a convincing argument for how children construct social understanding through social interaction. Certainly mothers are important in family interaction; however, sibling interaction may also be key in the process of developing social understanding. In particular, the highly affective and reciprocal dynamics of the sibling relationship in both positive and conflictual interaction may be critical.

It is divided into four sections covering science as a whole, the new technologies of the postmodern era, bio-medical discourses, and nature. A distinguished cast of contributors explores the central feminist concerns in each arena, through the central metaphors of monster, mother goddess and cyborg. They look at the consequences of gynogenesis, postmodern eco-buddhism in heathcare, sexual violence in cyberspace, the postmodernization of menopause, the dolphin as androgyne and feminist environmentalism.

Vibrant Death links philosophy and poetry-based, corpo-affectively grounded knowledge seeking. It offers a radically new materialist theory of death, critically moving the philosophical argument beyond Christian and secular-mechanistic understandings. The book's ethico-political figuration of vibrant death is shaped through a pluriversal conversation between Deleuzean philosophy, neo-vitalist materialism and the spiritual materialism of decolonial, queerfeminist poet and scholar Gloria Anzaldua. The book's posthuman deexceptionalizing of human death unfurls together with a collection of poetry, and autobiographical stories. They are analysed through the (...) lens of a posthuman, queerfeminist revision of the method of autophenomenography (phenomenological analysis of autobiographical material). Nina Lykke explores the speaking position of a mourning, queerfeminine "I", who contemplates the relationship with her dead beloved lesbian life partner. She reflects on her enactment of processes of co-becoming with the phenomenal and material traces of the deceased body, and the new assemblages with which it has merged through death's material metamorphoses: becoming-ashes through cremation, and becoming-mixed-with-algae-sand when the ashes were scattered across a seabed made of fiftyfive million-year-old, fossilized algae. It is argued that the mourning "I"'s intimate bodily empathizing (theorized as symphysizing) with her deceased, queermasculine beloved life partner facilitates the processes of vitalist-material and spiritual-material co-becoming, and the rethinking of death from a new and different perspective than that of the sovereign, philosophical subject. (shrink)

The volume documents, and makes an original contribution to, an astonishing period in twentieth-century philosophy_the progress of Arne Naess's ecophilosophy from its inception to the present. It includes Naess's most crucial polemics with leading thinkers, drawn from sources as diverse as scholarly articles, correspondence, TV interviews and unpublished exchanges. The book testifies to the skeptical and self-correcting aspects of Naess's vision, which has deepened and broadened to include third world and feminist perspectives. Philosophical Dialogues is an essential addition to the (...) literature on environmental philosophy. (shrink)

Background Family involvement in nursing homes is generally recognized as highly valuable for residents, staff and family members. However, family involvement continues to be challenging in practice. Aim To contribute to the dialogue about family involvement and develop strategies to improve family involvement in the nursing home. Methods This interpretative synthesis consists of a thematic analysis and care ethical interpretation of issues regarding family involvement from the perspective of families in nursing homes reported in literature. Findings This study reveals the (...) complexities of family involvement in the nursing home by drawing attention to the moral dimension of the issues experienced by families, as seen through the theoretical lens of Baier’s care ethical concept of trust as a theoretical lens. The synthesis of literature resulted in a thematic categorization of issues reported by families, namely, family–staff relationship, psychosocial factors and organizational circumstances. The care ethical interpretation of the synthesis of literature showed that the concept of trust resonates with all reported issues. Trust evolves over time. Early issues are mostly related to getting to know each other. Secondly, families want to experience that staff are competent and of good will. Difficult feelings families may have, such as guilt or loneliness, and dealing with the deterioration of the loved one puts families in a vulnerable position. This power imbalance between family and staff impedes a trusting relationship. Issues related to organizational circumstances, such as understaffing, also undermine families' trust in staff and the nursing home. Discussion and conclusion Baier’s theoretical concept of trust provides a deeper insight into the moral dimension of family involvement from the perspective of families in the nursing home. To improve family involvement in practice, we propose to aim future interventions at reinforcing trust in the relationship between family and staff as well as in the organizational context in which these care relationships occur. (shrink)

A series of recent arguments purport to show that most counterfactuals of the form if A had happened then C would have happened are not true. These arguments pose a challenge to those of us who think that counterfactual discourse is a useful part of ordinary conversation, of philosophical reasoning, and of scientific inquiry. Either we find a way to revise the semantics for counterfactuals in order to avoid these arguments, or we find a way to ensure that the relevant (...) counterfactuals, while not true, are still assertible. I argue that regardless of which of these two strategies we choose, the natural ways of implementing these strategies all share a surprising consequence: they commit us to a particular metaphysical view about chance. (shrink)

In this groundbreaking study, Nina Gurianova identifies the early Russian avant-garde as a distinctive movement in its own right and not a preliminary stage to the Constructivism of the 1920s. Gurianova identifies what she terms an “aesthetics of anarchy”—art-making without rules—that greatly influenced early twentieth-century modernists. Setting the early Russian avant-garde movement firmly within a broader European context, Gurianova draws on a wealth of primary and archival sources by individual writers and artists, Russian theorists, theorizing artists, and German philosophers. (...) Unlike the post-revolutionary avant-garde, which sought to describe the position of the artist in the new social hierarchy, the early Russian avant-garde struggled to overcome the boundaries defining art and to bridge the traditional gap between artist and audience. As it explores the aesthetics embraced by the movement, the book shows how artists transformed literary, theatrical, and performance practices, eroding the traditional boundaries of the visual arts and challenging the conventions of their day. (shrink)

Temporal ersatzism is the view that past entities exist, but are not concrete. The view is analogous to modal ersatzism, according to which merely possible worlds exist, but are not concrete. The goal of this paper is to give the reader a sense of the scope of available temporal ersatzist views, the ways in which the analogy with modal ersatzism may be helpful in characterizing and defending those views, and the sorts of considerations that are relevant when evaluating particular versions (...) of temporal ersatzism. (shrink)

Sustained neural activity during the delay phase of spatial working memory tasks is compelling evidence for the neural correlate of active storage and maintenance of spatial information, however, it does not provide insight into specific mechanisms of spatial coding. This activity may reflect a range of processes, such as maintenance of a stimulus position or a prepared motor response plan. The aim of our study was to examine neural evidence for the use of different coding strategies, depending on the characteristics (...) and demands of a spatial working memory task. Thirty-one and 44 participants performed a spatial working memory task while we measured their brain activity using fMRI in two separate experiments. Participants were asked to remember the position of a briefly presented target stimulus and, after a delay period, to use a joystick to indicate either the position of the remembered target or an indicated non-matching location. The task was designed so that the predictability of the response could be manipulated independently of task difficulty and memory retrieval process. We were particularly interested in contrasting conditions in which participants could use prospective coding of the motor response or had to rely on retrospective sensory information. Prospective motor coding was associated with activity in somatomotor, premotor, and motor cortices and increased integration of brain activity with and within the somatomotor network. In contrast, retrospective sensory coding was associated with increased activity in parietal regions and increased functional connectivity with and within secondary visual and dorsal attentional networks. The observed differences in activation levels, dynamics of differences over trial duration, and integration of information within and between brain networks provide compelling evidence for the use of complementary spatial working memory strategies optimized to meet task demands. (shrink)

To organise future behaviour, it is important to remember both the central and contextual aspects of a situation. We examined the impact of contextual threat or safety, learned through verbal instructions, on face identity recognition. In two studies (N = 140), 72 face–context compounds were presented each once within an encoding session, and an unexpected item/source recognition task was performed afterwards (including 24 new faces). Hierarchical multinomial processing tree modelling served to estimate individual parameters of item (face identity) and source (...) memory (threat or safety context) as well as guessing behaviour. Results show that language was highly effective in establishing threatening and safe context conditions. In Study 1, a fleeting picture stream (1 s per picture) led to poor item and source recognition. Prolonged presentation times (Study 2 with 6 s per picture) improved face memory but no contextual modulation was observed. Thus, incidental face learning was surprisingly poor and rapidly changing contextual settings might have interfered with the accurate encoding of face identity information and item–source binding. (shrink)

This article takes Viviana Zelizer’s (1985) Pricing the Priceless Child to the new millennium. Zelizer documented the transformation between the 19th and 20th century from an “economically useful” to an “emotionally priceless” child. She observed that by the 1930s, American children were practically economically worthless but invested with significant emotional value. What has happened to this emotionally priceless child at the dawn of the new millennium? Has there been a new transformation in the social value of children, and, if so, (...) what might have such a transformation entailed? To address these questions, we examine overtime trends that point to increasing devotion of resources and time to children’s education, a key input in the exceedingly influential human capital theory, which connects investment into children’s human capital with their future market value. Therefore, we argue that the priceless child 2.0 is a useful-to-be human capital investment child. We use four empirical examples of overtime growth in children’s human capital investment: (a) enrollments in early childhood education, (b) federal spending on early education, (c) federal spending on K-12 programs, and (d) parental spending on child care, education and extracurricular activities. In the conclusion, we discuss some potential consequences and concerns about raising children as human capital investment. (shrink)

The theory of causal Bayes nets [15, 19] is, from an empirical point of view, currently one of the most promising approaches to causation on the market. There are, however, counterexamples to its core axiom, the causal Markov condition. Probably the most serious of these counterexamples are EPR/B experiments in quantum mechanics (cf. [13, 23]). However, these are also the only counterexamples yet known from the quantum realm. One might therefore wonder whether they are the only phenomena in the quantum (...) realm that create problems for causal Bayes nets. The aim of this paper is to demonstrate that not only the phenomenon of quantum correlations in EPR/B experiments create problems for causal Bayes nets, but also the temporal evolution of quantum systems, which is described as dualistic by quantum mechanics. For this purpose, it is shown that single photon experiments in a Mach-Zehnder interferometer (MZI) violate the causal Markov condition as well. It is then argued, however, that the Markov violation does not occur under the de Broglie-Bohm interpretation of Bohmian mechanics. (shrink)

Experience has shown that the application of ethical guidelines developed for research in developed countries to research in developing countries can be, and often is, impractical and raises a number of contentious issues. Various attempts have been made to provide guidelines more appropriate to the developing world context; however, to date these efforts have been dominated by the fields of bioscience, medical research and nutrition. There is very little advice available for those seeking to undertake collaborative social science or natural (...) science research in developing countries and what is there tends to be held within disparate sources. Charting the development of a set of ethics documentation for future use by the Ecosystem Services for Poverty Alleviation (ESPA) programme research community, this paper outlines past and present attitudes towards ethics procedures amongst this community and suggests ways in which ethics procedures might be made more relevant and user-friendly to researchers working in this area. (shrink)

Cartwright (Synthese 121(1/2):3–27, 1999a; The dappled world, Cambridge University Press, Cambridge, 1999b) attacked the view that causal relations conform to the Markov condition by providing a counterexample in which a common cause does not screen off its effects: the prominent chemical factory. In this paper we suggest a new way to handle counterexamples to Markov causation such as the chemical factory. We argue that Cartwright’s as well as similar scenarios feature a certain kind of non-causal dependence that kicks in once (...) the common cause occurs. We then develop a representation of this specific kind of non-causal dependence that allows for modeling the problematic scenarios in such a way that the Markov condition is not violated anymore. (shrink)

I argue against the common and influential view that non-trivial chances arise only when the fundamental laws are indeterministic. The problem with this view, I claim, is not that it conflicts with some antecedently plausible metaphysics of chance or that it fails to capture our everyday use of ‘chance’ and related terms, but rather that it is unstable. Any reason for adopting the position that non-trivial chances arise only when the fundamental laws are indeterministic is also a reason for adopting (...) a much stronger, and far less attractive, position. I suggest an alternative account, according to which chances are probabilities that play a certain explanatory role: they are probabilities that explain associated frequencies. (shrink)

Recently, McGinn has proposed a new theory of disgust. This theory makes empirical claims as to the history and function of disgust, yet does not take into account contemporary scientific research on the subject. This essay evaluates his theory for its merits as an account of disgust, and as a piece of scholarship more generally, and finds it lacking.

Why choose less money over more when no one is watching? A central tenet of economics is that this behaviour can be explained by intrinsic motivation. But what does intrinsic motivation entail? What encourages it? This paper answers these questions through a Smithian lens: moral motivation includes not only a naturally strong love of praise and dread of blame but also a natural, and stronger, love of being worthy of praise and dread of being worthy of blame, even if neither (...) is necessarily given. I rely on quantitative and qualitative data from economic experiments to illustrate this claim. While the current scholarship on Smith has applied his theory to situations in which our actions either evoke reactions from others or have monetary consequences for them, I extend his insights to receiver games and dice-rolling games aimed at eliciting self-regarding concerns, that is, actions affecting the interests of only ourselves. I argue that these games accentuate the strength of the love of praiseworthiness in guiding behaviour, emphasising its immediate reference to others and foundation in intentions along with outcomes. (shrink)

There is a widespread notion, both within the sciences and among the general public, that mental deterioration can rob individuals of their identity. Yet there have been no systematic investigations of what types of cognitive damage lead people to appear to no longer be themselves. We measured perceived identity change in patients with three kinds of neurodegenerative disease: frontotemporal dementia, Alzheimer’s disease, and amyotrophic lateral sclerosis. Structural equation models revealed that injury to the moral faculty plays the primary role in (...) identity discontinuity. Other cognitive deficits, including amnesia, have no measurable impact on identity persistence. Accordingly, frontotemporal dementia has the greatest effect on perceived identity, and amyotrophic lateral sclerosis has the least. We further demonstrated that perceived identity change fully mediates the impact of neurodegenerative disease on relationship deterioration between patient and caregiver. Our results mark a departure from theories that ground personal identity in memory, distinctiveness, dispositional emotion, or global mental function. (shrink)

The article discusses the phenomenon of Russian Neo-Kantianism in the early twentieth century, looks at the main reasons for interest in Neo-Kantianism, and analyzes why German Neo-Kantian centers were so popular among Russian students and scholars at the turn of the twentieth century. The author points to the institutions where Neo-Kantianism took root and introduces the individuals who became the leaders of these institutions. The article gives a detailed overview of the themes and issues that occupied Russian Neo-Kantians before 1917, (...) as well as the development of these issues in the postrevolutionary period both in Soviet Russia and by Russian Neo-Kantians abroad. An emphasis is made on the original ideas and concepts formulated by Russian Neo-Kantians. (shrink)

Disgust, the emotion of rotting carcasses and slimy animalitos, finds itself at the center of several critical questions about human culture and cognition. This article summarizes recent developments, identify active points of debate, and provide an account of where the field is heading next.

Grand unified theories of messy topics like emotion tend to fail at capturing all the important dimensions of their subject. Why is this? I take on this question while responding to commentaries.

Introduction:The effects of specific suggestions are usually studied by measuring parameters that are directly addressed by these suggestions. We recently proposed the use of a uniform, unrelated, and objective measure like maximal muscle strength that allows comparison of suggestions to avoid nocebo effects and thus to improve communication. Since reduced breathing strength might impair respiration and increase the risk of post-operative pulmonary complications, the aim of the present study was to evaluate the effects of the suggestions on respiratory muscle power. (...) Both the identification and neutralization of negative suggestions in the clinical context and stimulating suggestions could improve breathing force, a predictor of physical fitness and convalescence.MethodsIn 50 healthy, adult volunteers, respiratory muscle strength was measured by maximal inspiratory and expiratory pressures, as well as by maximal inspiratory and expiratory flows. Baseline was compared to values after application of eleven suggestions, five out of clinical context, including memory of negative or positive past, risk information for informed consent, and a non-verbal suggestion. Six stimulating suggestions included self-affirmation, empowering words, a heroic mirror image, and an imagination.ResultsAll suggestions showed an impact on respiratory muscle strength, indicating placebo and nocebo effects. No single parameter could represent the breathing force in its complexity, however, trends and different specific aspects of it were measured. The strongest reaction was observed with the recall of a previous negative situation resulting in a reduction in expiratory flow to 96.1% of baseline. After risk information, a decrease was observed in three of the parameters, with the highest extend in expiratory pressure by 4.4%. This nocebo effect was neutralized by adding positive aspects to the risk information. Every intended strengthening suggestion resulted in statistically significant increases of at least one parameter, with changes of up to 10%, indicating placebo effects. Here, expiration was more affected than inspiration. Sex was the only influencing factor reaching statistical significance, with stronger reactions in women.ConclusionRespiratory muscle strength proved to be sensitive to suggestions with clinical context, as well as suggestions intended for stimulation. With this objective measurement, evaluation, and comparison of different suggestions is possible to help avoid nocebo effects. The demonstrated effect of supporting suggestions can be followed up and used in clinical practice. (shrink)

In Rethinking Language Arts: Passion and Practice, author Nina Zaragoza uses the form of letters to her students to engage pre-service teachers in reevaluating teaching practices, thus bringing to life a vision of an alternative classroom environment in which the teacher is the prime mover and creative leader. Zaragoza discusses and explains the need for teachers to be decision makers, reflective thinkers, political beings, and agents of social change in order to create a positive and inclusive classroom setting. This (...) book is both a critical text that deconstructs the way language arts are traditionally taught in our schools as well as a visionary text with clear, no-nonsense directions on how to provide much needed change in our schools. (shrink)

This paper attempts to clarify the concept of relational work for understanding economic life as proposed by Viviana Zelizer. To do so, it first compares the concept to similar notions used in other disciplinary fields. Second, it reinterprets some exemplary economic sociology studies by using the relational work lens to clarify the concept’s utility for empirical analysis. Third, it speculates about the place of relational work in the theoretical toolkit of economic sociologists, in particular its relation to embeddedness. The paper (...) concludes by arguing for the utility of the concept to integrate structural, cultural, and power-focused analyses of economic life, to highlight the often-overlooked role of emotions in economic exchange, and to ground an alternative to rational action theory in economic sociology. (shrink)

Presentism is the view that only presently existing things exist. Actualism is the view that only actually existing things exist. Although these views have much in common, the position we take with respect to one of them is not usually thought to constrain the position that we may take toward the other. In this paper I argue that this standard attitude deserves further scrutiny. In particular, I argue that the considerations that motivate one common objection to presentism—the grounding objection—threaten to (...) give rise to an analogous grounding objection to actualism. Those who are moved by grounding considerations to give up presentism should either be moved by analogous considerations to give up actualism as well or be prepared to undertake quite a bit of further work in order to defend their position. (shrink)

Recent investigations in neurogenomics have opened up new lines of research into a crucial genetic problem—the pathway from genes to behavior. This paper concentrates on the involvement of protein elements in the brain neurotransmitter serotonin (5‐HT) system in the genetic control of aggressive behavior. Specifically, it describes: (1) the effect of the knockout of MAO A, the principal enzyme in 5‐HT degradation, (2) the association of intermale aggression with the polymorphism in the Tph2 gene encoding the key enzyme in 5‐HT (...) synthesis in the brain, tryptophan hydroxylase (TPH), and (3) the effect of selective breeding for nonaggressive behavior on 5‐HT metabolism, TPH activity and 5‐HT1A receptors in the brain. The review provides converging lines of evidence that: (1) brain 5‐HT contributes to a critical mechanism underlying genetically defined individual differences in aggressiveness, and (2) genes encoding pivotal enzymes in 5‐HT metabolism (TPH and MAO A), 5‐HT‐transporter, 5‐HT1A and 5‐HT1B receptors belong to a group of genes that modulate aggressive behavior. BioEssays 28: 495–503, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

Understanding how citizens create contexts for open-ended political conversation in everyday life is an important task for social research. The lack of theoretical attention to political conversation in the current renaissance of studies of "civil society" and "the public sphere "precludes a thoroughly social understanding of civic life. Participant-observation in U. S. recreational, volunteer, and activist groups shows how the very act of speaking itself comes to mean different things in different civic contexts. It shows dramatic contextual shifts-the more public (...) the context, the less public-spirited the discourse. Institutions encouraged groups to avoid public, political conversation. One group challenged the dominant etiquette for citizenship; the others considered talking politics "out of place " almost everywhere. The ways groups relate to public speech itself are themselves meaningful; the concept of "civic practices" highlights how groups develop not just the power to make a particular political program public, but the power to make the public itself. (shrink)

The concept of ‘digital phenotyping’ was originally developed by researchers in the mental health field, but it has travelled to other disciplines and areas. This commentary draws upon our experiences of working in two scientific projects that are based at the University of Oxford’s Big Data Institute – The RADAR-AD project and The Minerva Initiative – which are developing algorithmic phenotyping technologies. We describe and analyse the concepts of digital biomarkers and computational phenotyping that underlie these projects, explain how they (...) are linked to other research in digital phenotyping and compare and contrast some of their epistemological and ethical implications. In particular, we argue that the phenotyping paradigm in both projects is grounded on an assumption of ‘objectivity’ that is articulated in different ways depending on the role that is given to the computational/digital tools. Using the concept of ‘affordance’, we show how specific functionalities relate to potential uses and social implications of these technologies and argue that it is important to distinguish among them as the concept of digital phenotyping is increasingly being used with a variety of meanings. (shrink)