This book analyzes unobvious relations between historical definitions of the face and its contemporary usage in popular culture and social media, like Facebook or Instagram. Bringing together a wide range of methodologies, it includes essays from manifold disciplines of the humanities such as philosophy, literary and art criticism, media and television studies, game studies, sociology and anthropology. The authors focus on both metaphorical and material meanings of the face. They grapple with crucial questions about modernity, modern and postmodern subjectivity, as (...) well as with origins of certain linguistic terms and popular, colloquial phrases based on the concept of the face. (shrink)

While the implementation of digital technology in psychiatry appears promising, there is an urgent need to address the implications of the absence of ethical design in the early development of such technologies. Some authors have noted the gap between technology development and ethical analysis and have called for an upstream examination of the ethical issues raised by digital technologies. In this paper, we address this suggestion, particularly in relation to digital healthcare technologies for patients with schizophrenia spectrum disorders. The introduction (...) of digital technologies in psychiatry offers a broad spectrum of diagnostic and treatment options tailored to the health needs and goals of patients’ care. These technologies include wearable devices, smartphone applications for high-immersive virtual realities, smart homes, telepsychiatry and messaging systems for patients in rural areas. The availability of these technologies could increase access to mental health services and improve the diagnostics of mental disorders.Additional Instruction AbstractIn this descriptive review, we systematize ethical concerns about digital technologies for mental health with a particular focus on individuals suffering from schizophrenia. There are many unsolved dilemmas and conflicts of interest in the implementation of these technologies, such as (1) the lack of evidence on efficacy and impact on self-perception; (2) the lack of clear standards for the safety of their daily implementation; (3) unclear roles of technology and a shift in the responsibilities of all parties; (4) no guarantee of data confidentiality; and (5) the lack of a user-centered design that meets the particular needs of patients with schizophrenia. mHealth can improve care in psychiatry and make mental healthcare services more efficient and personalized while destigmatizing mental health disorders. To ensure that these technologies will benefit people with mental health disorders, we need to heighten sensitivity to ethical issues among mental healthcare specialists, health policy makers, software developers, patients themselves and their proxies. Additionally, we need to develop frameworks for furthering sustainable development in the digital technologies industry and for the responsible usage of such technologies for patients with schizophrenia in the clinical setting. We suggest that digital technology in psychiatry, particularly for schizophrenia and other serious mental health disorders, should be integrated into treatment with professional supervision rather than as a self-treatment tool. (shrink)

Dans le champ de la linguistique francaise, Olga Galatanu est de ceux qui ont muni l'analyse du discours et des interactions verbales d'un modele semantique de description. La Semantique des Possibles Argumentatifs qu'elle developpe depuis une vingtaine d'annees adhere aux visions argumentative, stereotypique, referentielle, cognitiviste de la langue, et s'attache a rendre compte de la construction des representations en langue et en discours.<BR> Les articles que ses collaborateurs et amis lui offrent dans ce volume se rapportent de pres ou (...) de loin a la SPA. Certains en partagent les postulats: sens referentiel et denomination, interfaces semantique-syntaxe et semantique-pragmatique, construction discursive du sens, valeurs; d'autres reprennent et developpent des elements specifiques de la SPA: possibles argumentatifs, deploiements argumentatifs, modalites; d'autres encore montrent les convergences et complementarites entre la SPA et des theories voisines.<BR> Les analyses portent notamment sur l'attitude metalinguistique des locuteurs, la malleabilite semantique des mots, la negociation des sens et des valeurs, les principes et strategies discursives qui regulent la communication, l'heterogeneite discursive, la presentation de soi, la construction d'objets discursifs, les actes de langage indirects, etc.". (shrink)

This article examines the discourse competence of high-functioning children with autistic spectrum disorders to participate in narrative introduction sequences with family members. The analysis illuminates the children’s own efforts to launch narratives, as well as their ability to build upon the contributions of others. Ethnographic, discourse analytic methodology is integrated with the theory of discourse organization and the weak central coherence account of autism. Introductions of both personal experience narratives as well as fictional narratives are examined. The children were especially (...) competent in the use of stable introductory practices when launching fictional narratives, pre-organized by the media of expression. Their challenge was not in the introduction, but in the narrative co-telling, which often was not globally organized over an extended course of propositions. The heterogeneity of the ASD children’s discourse competence and its implications for discourse analysis are discussed. (shrink)

Source: Author: Olga Posudiyevska This study concentrates on the analysis of early works by Rudyard Kipling who was born into the family of English colonists to India, thus becoming a representative of the newly formed Anglo-Indian society. The writer’s sketch Anglo-Indian Society and his collection of short stories Plain Tales from the Hills depict the characteristic features of Anglo-Indians’ worldview and lifestyle, which are revealed and analyzed by the author of the article. Special attention is paid to biographical factors (...) influencing the author’s choice of Anglo-Indian topic at the beginning of his writing career. The researcher concludes that Kipling presents in his works an outline of Anglo-Indian society which emerged from the writer’s observations of Anglo-Indians’ lives during his work as a reporter. Striving for credibility in consideration of advantages and shortcomings of Anglo-Indian worldview and lifestyle, the author tries to occupy the position of the unconcerned observer, being capable of assessing the situation with fresh mind. Kipling disguises himself under the image of the hero-narrator, being either a tourist traveler from abroad, or a reporter, accustomed to collecting factual material for the local paper, in such a way receiving an opportunity to speak ironically and sometimes even sarcastically about certain models of behavior, accepted by Anglo-Indians. ]]>. (shrink)

У статті викладено організаційно-методологічний підхід до бюджетування для формування багаторівневої системи бюджетів холдингу. Розкрито особливості узагальнення консолідованої інформації корпоративних груп, обґрунтовано основний метод бюджетування під час підготовки бюджетів різних рівнів, запропоновано методологію бюджетування підприємств у складі холдингу, яка полягає в розробці комплексної моделі бюджетного процесу, що призведе до підвищення фінансово-економічної ефективності та фінансової стійкості організації.

The right to a fair trial is implemented in our criminal procedure and is one of the core values of our criminal justice system. This right is absolute and can’t be limited on any legal base. Its essence is fair and public hearing by an independent and impartial court with guaranteeing of all the minimum rights of the defendant. One of those minimum rights is the right of equity of arms between the parties, the prosecutor and the defense. In our (...) Law on Criminal Procedure, it is provided that the defense has the same rights and duties as the prosecutor except those rights that belong to the prosecutor as a state authority. Therefore, the purpose of this article is elaborating the right of ‘equity of arms’ and its misunderstanding in practice. Hence, we intend to show some case studies in which some evidence are not considered by the court just because they are not proposed by the prosecutor and they are crucial for the verdict. (shrink)

Globalization processes mean, among other things, the spread of trends that determine the socio-religious development of a region to other spatial areas. This does not happen with an inevitable necessity, it is not a ubiquitous feature of globalization, but it does happen with a very high probability. Moreover, when it comes to development within the same confessional systems. In this context, it is pertinent to note that some of the widespread forms of religious practices in Ukraine today, and moreover, religious (...) structures, fifteen or twenty years ago, seemed to be exclusively Western. This is especially true of the large number of denominations, movements and movements that are Protestant in origin and are referred to as "evangelical" in English literature. (shrink)

Confronted with an unprecedented scale of human-induced environmental crisis, there is a need for new modes of theorizing that would abandon human exceptionalism and anthropocentrism and instead focus on developing environmentally ethical projects suitable for our times. In this paper, we offer an anti-anthropocentric project of an ethos for living in the Anthropocene. We develop it through revisiting the notion of sustainability in order to problematize the linear vision of human-centric futurity and the uniform ‘we’ of humanity upon which it (...) relies. We ground our analyses in posthumanism and material feminism, using works by posthumanist and material feminist thinkers such as Stacy Alaimo, Rosi Braidotti, Donna Haraway and Jane Bennett, among others. In dialogue with them, we offer the concept of posthuman sustainability that decenters the human, re-positions it in its ecosystem and, while remaining attentive to difference, fosters the thriving of all instances of life. (shrink)

In common law jurisdictions, legal professionals cite facts and legal principles from precedent cases to support their arguments before the court for their intended outcome in a current case. This practice stems from the doctrine of stare decisis, where cases that have similar facts should receive similar decisions with respect to the principles. It is essential for legal professionals to identify such facts and principles in precedent cases, though this is a highly time intensive task. In this paper, we present (...) studies that demonstrate that human annotators can achieve reasonable agreement on which sentences in legal judgements contain cited facts and principles. We further demonstrate that it is feasible to automatically annotate sentences containing such legal facts and principles in a supervised machine learning framework based on linguistic features, reporting per category precision and recall figures of between 0.79 and 0.89 for classifying sentences in legal judgements as cited facts, principles or neither using a Bayesian classifier, with an overall κ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\kappa$$\end{document} of 0.72 with the human-annotated gold standard. (shrink)

In the Borisova’s O. V. article on the basis of analysis of works of some medieval Arabic authors the different models of historical process open up and the of genius attempt of the sharp changing of the Koran picture of the world, accomplished by the Arabic theologian and philosopher Ibn Haldun, is analysed, that, however, appeared unsuccessful. However a negative result is in science is too a result. On some important features of works of the Arabic authors paid attention in (...) science first. (shrink)

In this article, the relationship between ethics in general and business ethics in particular to Stoic philosophy is investigated. Stoic ethics is used as a research tool, which step-by-step deciphers the position of the human as a functional part of a larger organization, such as the natural environment or civil society. Ethics is inextricably linked to the rational, free choice of what is right for both the individual and the total organism. Ethical rightness imposes a form of rational order within (...) the organization, in the sense that each part must perform the function appropriate to its abilities. At the maximum degree of ethical integration stands the paradigm of the Stoic sage as a model of a virtuous leader, who is able to understand the causes of each decision or action and direct the organization towards the set goal. From this perspective, concepts such as leadership, organizational ethics, or corporate social responsibility acquire an objective status and view the philosophical cosmopolitanism of the Stoic sage as a timeless example of ethical rightness. (shrink)

Forthcoming with R. Maliks & E. Widmer (eds), Kant’s Early Followers in Political Philosophy. London: Routledge. Amongst the various early-feminist critical engagements with eighteenth-century European ideas on women, and Kant’s ideas on women in particular, a figure that merits special attention is Karolina – an unknown, semi-anonymous Polish woman who is known to us only by her first name. In 1779-80, Karolina published three essays in the Polish journal Monitor – essays that are amongst the very few female-authored essays published (...) in this venue and the only texts that address women’s educational and socio-political standing. Karolina’s implicit critique of Kant’s views on women offers a two-fold challenge. First, Karolina critiques the confinement of women to the private use of reason and thus to the sphere defined by their sexual nature. This argument relies on my novel reading of Kant’s notion of the private use of reason, which takes into account Kant’s understanding of ‘private’ as being deprived of our common humanity and being limited to some specific, contingent aspect of ourselves. According to this reading, the notion of the private use of reason encompasses a broader category of individuals and cases – women, children, and domestic servants – i.e., those who are without appropriate education and socio-political standing. Unlike men in professions such as military officer or tax collector, who can switch between private and public uses as the situation demands it, though, individuals without appropriate education and socio-political standing are confined to using their reason in a private way at all times. Second, Karolina opposes Kant’s relegation of women to domestic labor, arguing that limiting women to the household prevents them from developing intellectually and socially – something that they are both capable of and deserve. Karolina advocates for a more egalitarian division of labor between sexes, suggesting that both men and women share domestic responsibilities. This would allow women to pursue broader intellectual and social engagements (including learning how to make public use of reason), aligning with Kant’s ideals of human progress. Since it is precisely the material conditions that preclude women from becoming active citizens in Kant’s view, this critique thereby challenges the confinement of women to passive citizenship and the very category of passive citizenship itself. (shrink)

This article offers an anthropological perspective on autism, a condition at once neurological and social, which complements existing psychological accounts of the disorder, expanding the scope of inquiry from the interpersonal domain, in which autism has been predominantly examined, to the socio-cultural one. Persons with autism need to be viewed not only as individuals in relation to other individuals, but as members of social groups and communities who act, displaying both social competencies and difficulties, in relation to socially and culturally (...) ordered expectations of behavior. The article articulates a socio-cultural approach to perspective-taking in autism in three social domains: participating in conversational turn-taking and sequences; formulating situational scenarios; and interpreting socio-cultural meanings of indexical forms and behavior. Providing ethnographic data on the everyday lives of high-functioning children with autism and Asperger syndrome, the article outlines a cline of competence across the three domains, from most success in conversational turn-taking to least in inferring indexical meanings. Implications of these abilities and limitations are considered for theoretical approaches to society and culture, illuminating how members of social groups are at once shaped by, and are agents of, social life and cultural understanding. (shrink)

This article is devoted to Russian religious thinker Semyon L. Frank’s philosophical interpretation of Alexander S. Pushkin’s work. The article identifies the place and significance of the Pushkin...

In Spain, the introduction of the new Diploma in Nursing in 1977 saw the role of nurses shifting from that of medical assistants with technical skills to being independent members of the healthcare team with specific responsibility for providing professional nursing care. Here, we analyse the evolution of the nursing profession in Spain following the transfer of nurse education to universities, doing so through interviews with the first generation of academic tutors. This was a qualitative study using the method of (...) analytic induction and based on the principles of grounded theory. Participants were selected by means of theoretical sampling and then underwent in‐depth interviews. Steps were taken to ensure the credibility, transferability, dependability and confirmability of data. The main conclusion of the analysis is that there is a gap between a theoretical framework borrowed from the Anglo‐American context and a nursing practice that, in Spain, has traditionally prioritised the application of technical procedures, a role akin to that of a medical assistant. It is argued that a key factor underlying the way in which nursing in Spain has evolved in recent decades is the lack of conceptual clarity regarding what the role of the professional nurse might actually entail in practice. (shrink)

Since ancient times Ukrainian culture has been Europeanized and christened. The achievements of Ukrainian Orthodoxy have played an important role in this for centuries. Let's consider the main ideological church organizational achievements of the Ukrainian Orthodoxy that, in our opinion, are organically linked with the Ukrainian cultural sphere.

The purpose of the study is to analyze accounting and legal approaches to the definition of the term "accounts receivable" and to justify the need for its clarification to be fixed in regulatory documents. Scientific novelty: the definition of the term "accounts receivable" has been clarified using accounting and legal approaches, where it is proposed to understand the obligations of other legal entities and individuals to this economic entity for contributions to the authorized capital, for advances issued, for bills of (...) exchange receivable, for goods sold, monetary amounts issued under the report, arising on the basis of a law, contract or civil situation. As a result, the updated definition will make it possible to supplement Article 307 of the Civil Code of the Russian Federation, art. 3 of the Federal Law "On Accounting", Article 7 of the draft Federal Tax Service "Accounts Receivable and Payable ". (shrink)

The article deals the activities of social and political organizations of pro-Russian direction on the Crimea peninsula. The author defines that under the banner of maintaining relations with compatriots and the preservation of social and cultural traditions, was carried out targeted information campaign on the formation of anti-Ukrainian sentiment among the youth. Events on the Crimean peninsula, unfortunately, belong to insufficiently studied issues of recent history of Ukraine. Ukrainian historical opinion have demonstrated passivity on this issue and no sound labor (...) opposed promotional products of famous Russian historians and historical schools. Starting from the first day of the independence of Ukraine our "eastern neighbor" carried out targeted information pressing supported by numerous pro-Russian social organizations, which the peninsula has always been rich in. Types of propaganda rhetoric, methods and forms of action changed according to the political and military significance of events that took place. Рro-Russian social organizations have organized different initiatives to involve youth organizations. For example, there is the observance of the military patriotic youth camp Donuzlav anti NATO. (shrink)

The main indicators of assistance activity in the insurance market in Ukraine have been analyzed. Beneficial and negative trends of its development have been shown. The dynamics of the insurers' liquidation expenses structure and the payment of services expenses of the assistance establishments have been highlighted. Their structure has been shown due to the types of voluntary and compulsory insurance. The main problems hindering the effective development of the assistance services market have been characterized and the prospects of its development (...) have been offered. The aim of the research is to carry out comprehensive analysis of the current market of assistance services, to identify the main problems of their implementation and to point out the prospects of insurance market development. The dynamics of insurance bonuses and benefits including insurance compensation and services and the insurers' operating expenses concerning the payment of services of the assistance establishments has been analyzed on the basis of a sample survey of the main indicators of insurance market development due to the statistic data of National Committee of Financial Services. It has been revealed that majority of the insurance services provide settlement of insurance claims by offering assistance service. Alongside increasing of the share of insurance payment due to the contract providing the insurance service, allows the majority of insurance claims to be settled due to the payment of insurance compensation. Expenses on assistance services were the highest and the court expenses were the lowest in the structure of the insurer's liquidation expenses during 2011-2014. Expenses on services of the non-residential assistance establishments are low but they are increasing. It shows that emergency assistance to our citizens in the country and outside is being increased. Structure of assistance services in the voluntary and compulsory insurance market has been analyzed; main trends of assistance activity development according to the separate insurance services have been highlighted. In particular it was found out that the greatest amount of assistance services were provided due to the voluntary medical insurance, medical costs insurance, land transport insurance and compulsory insurance of civil liability of the owners of vehicles. On the basis of conducted analysis, we can draw a conclusion about the low level of assistance services market development. It is affected by negative trends of economic and political crisis, low solvency of insurers and the quality of insurance services, a lack of guaranties to provide emergency assistance in time, imperfect state regulation of assistance services provision, and a low level of institutional support. We offer to intensify the interaction between the insurers and assistance companies while providing insurance services including additional ones, insurance compensation, and settlement of insurance claims by ensuring emergency assistance in monetary and natural-material form. This will promote the increasing of quality of the insurance protection. (shrink)

Globalization in the XXI century is an objective phenomenon that manifests itself as a complex system with many nonlinear relationships between its subjects and objects. Globalization of the “new wave” has a number of specific characteristics and trends. They have led to the emergence of negative consequences and unexpected results of globalization. These tendencies do not presuppose the process of de-globalization, but they are a sign of the passage from one model of globalization to another, from the monocentric structure of (...) the world to the polycentric one, which affords ground for its nomination as “non-global globalization”. The article compares the approaches and achievements of Russian and Western globalistics. (shrink)

In this paper I describe basic features of traditional (British) emergentism and Popper’s emergentist theory of consciousness and compare them to the contemporary versions of emergentism present in connectionist approach in cognitive sciences. I argue that despite their similarities, the traditional form, as well as Popper’s theory belong to strong causal emergentism and yield radically different ontological consequences compared to the weaker, contemporary version present in cognitive science. Strong causal emergentism denies the causal closure of the physical domain and introduces (...) genuine new mental causal powers and genuine downward causation, while weak emergentism provides new insights in understanding the mechanisms and explanation that is compatible with physicalism. (shrink)

Визначення інвестиційної привабливості підприємств у вітчизняній науці традиційно вивчається з точки зору факторів економічного характеру. Досліджень, у яких представлені наукові підходи, які розкривають неекономічні чинники залучення інвестицій, в Україні практично немає. У статті досліджено можливості залучення інвестування під проекти розвитку промислових підприємств на основі рефлексивного підходу. Обґрунтовано й розроблено відповідний алгоритм залучення інвестицій, що включає блоки підготовки, розгляду та практичної реалізації фінансування обраних проектів при виборі стратегічної поведінки всіх учасників інвестування та розподілу ризиків між ними.

La legitimación del sufrimiento de las mujeres como voluntad de Dios ha sido una realidad expresada en muchas instancias, entre ellas, los contextos de guerra donde la violencia sexual contra las mujeres se utiliza como arma de guerra. En este horizonte, este artículo busca proponer una lectura feminista de la cruz de Cristo, buscando contrastar la violencia ejercida contra el cuerpo de las mujeres con la teoría de la expiación de nuestros pecados por la cruz de Cristo. Se parte de (...) la experiencia de las mujeres en el contexto de guerra colombiano para, en un sgundo momento, interpretar esa realidad con los datos de la reflexión cristológica feminista de varias autoras que han abierto caminos para la recuperación de la dignidad y valor de las mujeres. Todo esto nos permite concluir en el inaplazable compromiso de una relectura feminista de la cruz para favorecer la paz y la justicia para todos y, por supuesto, para las mujeres víctimas de tanta y tan variada violencia. (shrink)

Résumé Les introductions des éditions de la Commission Léonine concernant les disciplines de la Faculté des arts, bien que datant parfois d’une trentaine d’années, constituent un instrument essentiel pour l’histoire intellectuelle du xiii e siècle, instrument dont on continue de se servir avec gratitude. De plus, la documentation réunie en vue de l’édition des œuvres de S. Thomas par toute une équipe et en particulier les notes prises sur les manuscrits par Louis-Jacques Bataillon se sont avérées indispensables pour la mise (...) au point du répertoire des maître ès arts parisiens, en cours de publication. (shrink)

Ancient critics reproached Xenocrates for beginning his work on the dialectic with a discussion of voice, and until now the question why he did so has never been systematically explored. Neither do we know why Xenocrates counted syllables, as Plutarch reports, and how he arrived at such an implausibly high number. In the first part of this paper, I show that Xenocrates’ interest in voice was suggested by Plato’s discussion of letters in his later dialogues, such as the Theatetus, the (...) Sophist, the Statesman, and the Philebus. Second, a fragment from Sextus attributed to Xenocrates confirms that Xenocrates allowed for various ‘levels’ of elements, and that explains why Theuth’s method, recommended in the Philebus, is applied to syllables. Finally, I address the very possibility of knowing the actual number of syllables and words, and address some of the problems connected to the reconstruction of the mathematical argument. (shrink)

L’article propose l’analyse de trois formes de manifestation de ce que nous avons appelé l’implicite argumentatif : à visée discursive, à visée sémantique et à visée lexicale. Dans la perspective théorique de la Sémantique des Possibles Argumentatifs, nous avons défini ce phénomène sémantico-discursif, comme la reconstruction, dans l’interprétation du sens d’un énoncé ou d’un ensemble d’énoncés, d’un élément signifiant ou d’une configuration d’éléments signifiants relevant de la nature argumentative de la signification d’un mot, présent ou absent de cet énoncé ou (...) de cet ensemble d’énoncés. L’article défend, illustre et argumente les fondements sémantiques de ces trois types d’implicite argumentatif, ancrés dans le potentiel discursif de la signification des mots et dans le potentiel du sens produit dans les instances de parole, de proposer des significations lexicales régénérées. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Feminist Studies 44, no. 1. © 2018 by Olga Zilberbourg 95 Olga Zilberbourg Helen More’s Suicide My retired colleague Marguerite called to tell me of Helen More’s suicide. “Of all the sad, ludicrous things people do to themselves!” She invited me over. “Thursday night, as usual. I could use the company of younger people.” It had been about a year since I’d first been invited to these (...) Thursdays —monthly literary and musical soirees Marguerite hosted in her living room. Helen had been a regular at Marguerite’s for several decades; the two women were close contemporaries and each a celebrity in her own field. Helen was scholar of the English Romantics at the same university where Marguerite had taught Flaubert, Zola, and Balzac, and where I was now a junior faculty member in the English department. I’d heard of Professor More long before I met her: she lectured at the university from the 1960s until being forced into retirement in 2006 ostensibly due to age. She had a reputation as a militant feminist who eagerly engaged in battles about appointments and promotions, and her politics could have had something to do with it. “Are they sure it was a suicide?” In person Helen was a quiet, reticent woman with a sly, sarcastic sense of humor, and the idea that she might’ve committed suicide seemed outlandish. Vague murder scenarios floated in my mind. A disgruntled student? A male professor, passed over for promotion years ago and blaming her for his career failure? 96 Olga Zilberbourg “Yes, quite. The details are unpleasant, but do you know what she wrote in her suicide note?” “Of course she left a note.” “She said, ‘Thanks for the trip. Love to all.’” I couldn’t help laughing. “Yet when you think that having written that, she took all those pills and put a plastic bag over her head,” Marguerite’s voice broke. “Anyway, it’s not a conversation to have over the telephone. Do come over.” On Thursday afternoon, having collected the student papers after the last exam of the semester, I took the subway down to Greenwich Village. Marguerite lived on a third floor walkup, in a wonderfully spacious and tall-ceilinged apartment that back in the 1970s she and her husband had converted from a pillow factory. Since her husband’s death ten years earlier, the apartment had slowly turned into a trap for Marguerite. She suffered from arthritis in her hands, shoulders, and knees, and walking up and down the stairs became a nearly impossible exercise. She ventured out once or twice a week with the assistance of a visiting nurse. The place could easily fetch three or four million dollars, and Marguerite could use the money. Yet she was reluctant to sell. “I’d rather go without bread than without my piano and my books,” she insisted. A feeling of reverence and trepidation caught my breath as I climbed the stairs to Marguerite’s apartment. One never knew what kind of celebrity of the arts or music world could show up on any given Thursday. In her lifetime, Marguerite had known everyone, from Sartre and de Beauvoir to Picasso and Chagall. In the last few years the circle of her acquaintances seemed to dwindle, and yet still world-renowned musicians, poets, playwrights sometimes appeared among the circle of her former colleagues and students. I rang the doorbell and waited for several minutes as Marguerite crept to the door. “I’m afraid you’re my only guest tonight,” she said through the door, struggling with the lock and the knob. Finally, she pushed the door open. “Several people cancelled because of the end of the semester, and then of course, there’s the funeral. But come in, come in—we’ll talk of that later.” Marguerite led me into the living room, heavily shaded from the street and dimly lit with two floor lamps. Decorated with musical instruments, piles of books on the floor and on the low tables, and bright Olga Zilberbourg 97 modernist watercolors on the walls, the room seemed to belong to a royal palace, a vast, untouchable space. Usually Helen or one of Marguerite ’s... (shrink)

This paper offers a reconstruction of Xenocrates’ theory of indivisibles which would not commit him to the idea of ‘jerky motion’ criticized by Aristotle in Physica VI, yet would perfectly square with Plato’s Timaeus, the basis of Xenocrates’ canon. Relying on Alexander’s, Porphyry’s, and Themistius’s accounts of his theory, as well on a detailed analysis of De lineis insecabilibus, I suggest that Xenocrates’ minima, contrary to what Aristotle implies, are not to be understood as more or less stable particulars, like (...) tiny chunks of matter, moving about or leaping in physical space from point A to point B. Yet Xenocrates’ minima do remain ‘physical’ and ‘corporeal’ in a more Platonic sense of these words, not presupposing any kind of leaping, jumping, or jerking. This explains why Xenocrates associated the sensible realm with one of the three Fates, namely Clotho. (shrink)

The issue of benefits in international clinical research is highly controversial. Against the background of wide recognition of the need to share benefits of research, the nature of benefits remains strongly contested. Little is known about the perspectives of research populations on this issue and the extent to which research ethics discourses and guidelines are salient to the expectations and aspirations existing on the ground. This exploratory study contributes to filling this void by examining perspectives of people in low-income South (...) African communities on benefits in international clinical research. Twenty-four individuals with and without experience of being involved in clinical research participated in in-depth interviews. Respondents felt that ancillary care should be provided to clinical research participants, while a clinical study conducted in particular community should bring better health to its members through post-trial benefits. Respondents' perspectives were grounded in the perception that the ultimate goal of international clinical research is to improve local health. We argue that perspectives and understandings of the respondents are shaped by local moral traditions rather than clinical research specificities and require attention as valid moral claims. It is necessary to acknowledge such claims and cultural worlds from which they emerge, thus building the foundation for equal and embracing dialogue to bridge different perspectives and handle contradicting expectations. (shrink)

In recent years, the biopharmaceutical industry has seen an increase in the development of so-called orphan drugs for the treatment of rare and neglected diseases. This increase has been spurred on by legislation in the United States, Europe, and elsewhere designed to promote orphan drug development. In this article, we examine the drivers of corporate social responsibility (CSR) activities in orphan drug markets and the extent to which biopharmaceutical firms engage in these activities with a strategic orientation. The unique context (...) of orphan drugs constitutes a research opportunity to test the applicability of existing theoretical perspectives on CSR and strategic CSR. Using Schwartz and Carroll’s (Bus Ethics Q, 13(4):503–530, 2003) three-domain approach to CSR and the literature on strategic CSR as a theoretical background, we employ a combination of semi-structured interviews and a quantitative website content analysis to study practices of biopharmaceutical firms in the United States and European Union. Our findings show that both US- and EU-based companies engaged in orphan drugs development perceive their involvement as a responsible business activity beyond the economic dimension of CSR. However, for the majority of these companies their CSR activities do not qualify as strategic according to the criteria established in the literature. We also find significant differences between larger and smaller firms in their use of CSR. Based on these findings, we make several suggestions regarding orphan drug legislation and other measures that might help firms exploit strategic CSR benefits. (shrink)