Mechanistic studies may be defined as ‘an experiment, using an intervention in healthy subjects or patients, to better understand human biology and/or disease’. Such studies provide useful physiological insights into clinical conditions in humans and expand our knowledge of physiology in health and disease. Well-planned mechanistic studies are therefore a vital step in progressing drug discovery in humans. It is important in such studies that the rights and safety of research participants are preserved, while at the same time not allowing (...) lengthy and complex approval procedures to stifle and potentially prohibit this type of research. (shrink)

Transgenic animals—animals with genes added to their deoxyribonucleic acid —will no longer be limited by the gene pool of their parents. Such animals are slated to be created expressly to provide vital and novel benefits for human beings. These animals can have desirable characteristics or traits from virtually any gene pool and may also possess properties not present in nature or available through conventional breeding. They will be created for the production of new medical and pharmaceutical products and to enhance (...) meat, dairy, and fiber production efficiency. (shrink)

Today, there is a growing interest in interdisciplinary studies between theology and natural sciences. This article will reveal some “core” problems in this interdisciplinary relationship. It investigates how cosmic eschatology and natural sciences can benefit the most from each other while dealing with the scenarios which cosmology presents. Doing so, the main emphasis will be on rediscovering the impact of the Resurrection in Christian theology and the possibility of launching a dialogue between natural sciences and theology concerning the new heaven (...) and the new earth. (shrink)

Eight of the eleven essays were written expressly for this book; all of the authors are deeply engaged in the debate over utility and rights, and their essays build upon and extend current thinking on the subject.

This essay proposes that liberal democracy cannot survive unless a monistic virtue ethics permeates its culture, A monistic philosophical conception of virtue ethics has its roots in natural law theory and, for that reason, offers a rationally defensible basis for a unified moral vision in a pluralistic society. Such a monistic virtue ethics--insofar as it is a virtue ethics--forms individual character so that a person not only knows how to act, but desires to act that way and, moreover, possesses the (...) integration of character to be able to act that way. This is a crucial consideration, for immoral choices create a bad character that inclines the individual to increasingly worse choices, A nation whose members lack moral virtue cannot sustain its commitment to freedom and equality for all. (shrink)

The most distinctive activities of humankind and the source of its greatest achievements are the scientific investigation of the world and the creation of art. Newton's Sleep examines their complementary roles in contemporary life and defends both against those who assert that science is spiritually empty and inherently dangerous and that art is trivialised by a lack of social mission.

This book explores the pervasiveness of poetry's impact on philosophy and, conversely, how philosophy has sometimes resisted or denied poetry's influence.

_Dante’s Deadly Sins_ is a unique study of the moral philosophy behind Dante’s master work that considers the _Commedia_ as he intended, namely, as a practical guide to moral betterment. Focusing on _Inferno_ and _Purgatorio_, Belliotti examines the puzzles and paradoxes of Dante’s moral assumptions, his treatment of the 7 deadly sins, and how 10 of his most powerful moral lessons anticipate modern existentialism. Analyzes the moral philosophy underpinning one of the greatest works of world culture Summarizes the _Inferno_ and (...) _Purgatorio_, while underscoring their moral implications Explains and evaluates Dante’s understanding of the ‘Seven Deadly Sins’ and the ultimate role they play as the basis of human transgression. Provides a detailed discussion of the philosophical concepts of moral desert and the law of _contrapasso_, using character case studies within Dante’s work Connects the poem’s moral themes to our own contemporary condition. (shrink)

The trial of Dmitri Karamazov embodies Dostoevsky’s general legal and moral philosophy. This book explains and critically analyses such notions as the rule of law, the adversary system of adjudication, the principle of universal moral responsibility, the plausibility of unconditional love, and the contours of human nature. The ballast for conclusions about all these ideas is an understanding of the relationship between individuals and their communities.