Results for 'Site specific'

983 found
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  1.  7
    Sitespecific mutagenesis of large DNA viral genomes.Frank J. Jenkins & Bernard Roizman - 1986 - Bioessays 5 (6):244-247.
    Sitespecific or target‐specific mutagenesis of viral DNA genomes, using a selectable marker system is a powerful tool for the analysis of the function of specific regions of large DNA genomes. Through these techniques the construction of vectors capable of delivering vaccines for the prevention of infectious disease in humans and animals is possible.
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  2. Aesthetic consciousness of site-specific art.Regina-Nino Kurg - 2013 - South African Journal of Philosophy 32 (4):349–353.
    The aim of this article is to examine Edmund Husserl’s theory of aesthetic consciousness and the possibility to apply it to site-specific art. The central focus will be on the idea of the limited synthetic unity of the aesthetic object that is introduced by Husserl in order to differentiate positional and aesthetic attitude towards the object. I claim that strongly site-specific art, which is a work of art about a place and in the place, challenges the (...)
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  3.  15
    Richard Serra’s Site-specific Artworks from the Phenomenological Perspective of Merleau-Ponty: Focusing on the Experience of the Body. 김정희 - 2024 - Phenomenology and Contemporary Philosoph 100:123-155.
    본 논문은 메를로-퐁티(Maurice Merleau-Ponty, 1908-1962)의 현상학적 시각으로 리처드 세라(Richard Serra, 1939- )의 장소 특정적 미술(site-specific art)에 관한 예술철학적 고찰을 목적으로 한다. 장소 특정적 미술에서 몸의 체험은 가장 중요한 작품완성 요소이다. 2차원의 회화를 감상하는데 있어서 기본적으로 몸의 일부인 눈의 시각적 체험이 중요하기는 하지만, 장소 특정적 미술에서는 시각 외에도 청각, 촉각, 후각, 운동감각과 공간 감각 등의 다양한 감각이 융합된 총체적 몸의 체험이 부각 된다. 이러한 몸의 체험은 육체와 정신으로 이분화되는 데카르트(René Descartes, 1596-1650)적 사유 방식이나 게슈탈트의 시지각 이론(Gestalttheorie)으로는 이해하기 힘들다고 할 (...)
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  4.  22
    Topological aspects of sitespecific DNA‐inversion.Roland Kanaar & Pieter van de Putte - 1987 - Bioessays 7 (5):195-200.
    Sitespecific recombination events are of fundamental importance in many biological systems. In vitro experiments using purified proteins and DNA sub‐strates are yielding insights into strand exchange mechanisms and synapsis of recombination sites. By examining results across a range of systems ‐ prokaryotic and eukaryotic ‐ two distinct classes of sitespecific recombinase enzymes can be defined.
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  5. Dismantling the frame: Site-specific art and aesthetic autonomy.Jason Gaiger - 2009 - British Journal of Aesthetics 49 (1):43-58.
    This paper examines the assumptions underpinning one of the constitutive elements of the modern concept of art: the idea of aesthetic autonomy. I argue that the orientation of recent art practice towards what has come to be termed ‘site-specificity’ is best understood as a progressive relinquishment of the principle of aesthetic autonomy. I develop this position through a close analysis of the work of Miwon Kwon. The paper is intended as a case-study that investigates the problematic relation between historical (...)
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  6.  30
    Site-specific long-range order in57Fe3Al measured by Mössbauer diffractometry.J. Y. Y. Lin & B. Fultz - 2003 - Philosophical Magazine 83 (22):2621-2640.
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  7.  8
    Internet Performances als site-specific art.Julia Glesner - 2003 - In Karl Anton Sprengard, Petra Gropp & Christoph Ernst (eds.), Perspektiven Interdisziplinärer Medienphilosophie. Transcript Verlag. pp. 275-288.
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  8.  49
    Playing with Fire-Space: Site-Specific Placement and the Techno-pharmacology of Maria Irene Fornes’s Mud.Guy Zimmerman - 2016 - Substance 45 (1):98-115.
    Many who write about the playwright Maria Irene Fornes’s work comment with reverence about the experience of watching those productions she herself directed.1 Managing somehow to combine frank depictions of cruelty and violence with an odd, otherworldly charm, Fornes’s direction conveyed a distinct sui generis quality that has deflected analytic scrutiny—the exterior operates in such an exquisite fashion one hesitates to lift the hood and look beneath. The set is a wooden room which sits on an earth promontory. The promontory (...)
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  9.  12
    Feminist practice in site-specific art of Korean artists since 2000. 이수정 - 2018 - Korean Feminist Philosophy 30:183-214.
    본 논문은 여성주의적 실천의 한 방식으로서 장소 특정적 예술이 가질 수 있는 가능성을 미학적 관점에서 탐구하는 것을 목표로 한다. 현대예술의 일반적인 형식중의 하나로서 자리잡은 장소특정적 예술은, 장소라는 요소가 비판적 예술 실천(수행)에서 어떻게 문제적이 되는지 장소적 실천 일반에 대해서 시사하는 바가 크다. 그 중에서도 본 논문은 장소와 여성주의적 실천의 관계를 다루며, 이를 위해, 2000년대 이후 한국 여성예술가의 네 개의 장소특정적 예술들 - 예술가의 서사와 담론이 중심이 되어 장소화나 특정 장소 선정이 이루어지는 두 가지 경우, 특정 지역 관련 기획전시의 경우, 특정 지역연구 (...)
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  10.  33
    Academic Virtues: Site Specific and Under Threat.Michael P. Levine & Damian Cox - 2016 - Journal of Value Inquiry 50 (4):753-767.
    Extract: Clearly, academic life takes place at the intersection of many social practices. If MacIntyre is right, the role-specific virtues of academic life should be understood in terms of these practices.2 Academic virtues are those excellences required to obtain the internal goods of the social practices constituting academic life. And the social practices of academic life are sustained, competitive and cooperative attempts to achieve a set of academic goals and realize academic forms of excellence. They are also sustained attempts (...)
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  11.  21
    The high costs of getting ethical and site-specific approvals for multi-centre research.Nicholas Graves, Brett G. Mitchell, Anne Gardner, Katie Page, Lisa Hall, Alison Farrington, Carla Shield, Megan J. Campbell & Adrian G. Barnett - 2016 - Research Integrity and Peer Review 1 (1).
    BackgroundMulti-centre studies generally cost more than single-centre studies because of larger sample sizes and the need for multiple ethical approvals. Multi-centre studies include clinical trials, clinical quality registries, observational studies and implementation studies. We examined the costs of two large Australian multi-centre studies in obtaining ethical and site-specific approvals.MethodsWe collected data on staff time spent on approvals and expressed the overall cost as a percent of the total budget.ResultsThe total costs of gaining approval were 38 % of the (...)
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  12. Re-Thinking Site-Specificity in Public Art: Some Critical and Philosophical Problems.Kevin Melchionne - 1998 - In Donald Kuspit (ed.), Art Criticism. pp. 36-49.
  13.  18
    The Affective Engagement of Dancers: The Case of Kitt Johnson and Her Site-Specific Work.Susanne Ravn & Giovanna Colombetti - 2024 - Journal of Consciousness Studies 31 (9):223-243.
    The article investigates how dancers can actively shape and handle the ways they are affected throughout their artistic practices. To do so, we adopt a phenomenological-ethnographic approach, analysing the dance-artist Kitt Johnson's site-specific performance production called Mellemrum ('the space between spaces'). We put ethnographically based interview data in a dialectical interaction with the existing notions of affectivity and affective scaffolding — showing their usefulness, while also noting the need for the further notion of what we call affective engagement. (...)
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  14. Suspending the Habit Body through Immersive Resonance:Hesitation and Constitutive Duet in Jen Reimer and Max Stein’s Site-Specific Improvisation.Rachel Elliott - 2018 - Critical Studies in Improvisation/ Études Critiques En Improvisation 12 (2):1 - 11.
    There is increasing appreciation for the role that location plays in the experience of a musical event. This paper seeks to understand this role in terms of our habitual relationships to place, asking whether and how being musical somewhere can expand and transform our habituated comportment there, and with what consequences. This inquiry is anchored in a series of site-specific improvised performances by Jen Reimer and Max Stein, and the theory and practice of the late experimental music pioneer (...)
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  15.  19
    In vivo biochemistry: Physical monitoring of recombination induced by sitespecific endonucleases.James E. Haber - 1995 - Bioessays 17 (7):609-620.
    The recombinational repair of chromosomal double‐strand breaks (DSBs) is of critical importance to all organisms, who devote considerable genetic resources to ensuring such repair is accomplished. In Saccharomyces cerevisiae, DSB‐mediated recombination can be initiated synchronously by the conditional expression of two sitespecific endonucleases, HO or I‐Scel. DNA undergoing recombination can then be extracted at intervals and analyzed. Recombination initiated by meiotic‐specific DSBs can be followed in a similar fashion. This type of ‘in vivo biochemistry’ has been used (...)
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  16.  42
    The Ras‐ERK pathway: Understanding sitespecific signaling provides hope of new anti‐tumor therapies.Fernando Calvo, Lorena Agudo-Ibáñez & Piero Crespo - 2010 - Bioessays 32 (5):412-421.
    Recent discoveries have suggested the concept that intracellular signals are the sum of multiple, site‐specified subsignals, rather than single, homogeneous entities. In the context of cancer, searching for compounds that selectively block subsignals essential for tumor progression, but not those regulating “house‐keeping” functions, could help in producing drugs with reduced side effects compared to compounds that block signaling completely. The Ras‐ERK pathway has become a paradigm of how space can differentially shape signaling. Today, we know that Ras proteins are (...)
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  17. Into the "imaginary" and "real" place : Stan Douglas's site-specific film and video projection.Ji-Hoon Kim - 2011 - In John David Rhodes & Elena Gorfinkel (eds.), Taking Place: Location and the Moving Image. University of Minnesota Press.
     
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  18.  18
    Toward an in situ phospho‐protein atlas: phospho‐ and sitespecific antibody‐based spatio‐temporally systematized detection of phosphorylated proteins in vivo.Toshiya Teraishi & Kenji Miura - 2009 - Bioessays 31 (8):831-842.
    The “Human Genome Project” was completed in 2003, shifting the focus to proteome and transcriptome research. One approach to proteomics involves the comprehensive visualization of the localization of proteins in all tissues and organs. We discuss in situ phospho‐protein atlases, which are systematized representations of the localization of proteins. Protein atlases provide important information about the identity and presence of proteins in specific organs, tissues and cells under physiological and pathological conditions. Antibody‐based immunohistochemical analysis is a powerful method for (...)
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  19. Click for larger view Trigger, 2005, Site-specific interactive installation, Pace University Digital Gallery [End Page 2]. [REVIEW]Disembodied Voices, How Safe Is & A. Separate Peace - 2006 - Diacritics 36 (3/4).
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  20.  17
    Species‐specific micro RNA regulation influences phenotypic variability.Eyal Mor & Noam Shomron - 2013 - Bioessays 35 (10):881-888.
    Phenotypic divergence among animal species may be due in part to species‐specific (SS) regulation of gene expression by small, non‐coding regulatory RNAs termed “microRNAs”. This phenomenon can be modulated by several variables. First, microRNA genes vary by their level of conservation, many of them being SS, or unique to a particular evolutionary lineage. Second, microRNA expression levels vary spatially and temporally in different species. Lastly, while microRNAs bind the 3′UTR of target genes in order to silence their expression, the (...)
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  21.  25
    Mechanisms regulating phosphatase specificity and the removal of individual phosphorylation sites during mitotic exit.Samuel Rogers, Rachael McCloy, D. Neil Watkins & Andrew Burgess - 2016 - Bioessays 38 (S1):24-32.
    Entry into mitosis is driven by the activity of kinases, which phosphorylate over 7000 proteins on multiple sites. For cells to exit mitosis and segregate their genome correctly, these phosphorylations must be removed in a specific temporal order. This raises a critical and important question: how are specific phosphorylation sites on an individual protein removed? Traditionally, the temporal order of dephosphorylation was attributed to decreasing kinase activity. However, recent evidence in human cells has identified unique patterns of dephosphorylation (...)
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  22. Transcending temporal variance : time-specificity, long distance performance and the intersubjective site.Emily DiCarlo - 2021 - In Arkadiusz Misztal, Paul Harris & Jo Alyson Parker (eds.), Time in variance. Boston: Brill.
     
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  23. Architecture and sites: a lesson from the categorization of artworks.Elisa Caldarola - 2021 - Croatian Journal of Philosophy 21 (1):5-24.
    Several contemporary architects have designed architectural objects that are closely linked to their particular sites. An in-depth study of the relevant relationship holding between those objects and their sites is, however, missing. This paper addresses the issue, arguing that those architectural objects are akin to works of site-specific art. In section (1), I introduce the topic of the paper. In section (2), I critically analyse the debate on the categorisation of artworks as site-specific. In section (3), (...)
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  24. Clinical Specificities in Obesity Care: The Transformations and Dissolution of ‘Will’ and ‘Drives’.Else Vogel - 2016 - Health Care Analysis 24 (4):321-337.
    Public debate about who or what is to blame for the rising rates of obesity and overweight shifts between two extreme opinions. The first posits overweight as the result of a lack of individual will, the second as the outcome of bodily drives, potentially triggered by the environment. Even though apparently clashing, these positions are in fact two faces of the same liberal coin. When combined, drives figure as a complication on the road to health, while a strong will should (...)
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  25.  15
    What the Papers Say: Cell type‐specific enhancement in the Drosophila embryo by consensus homeodomain binding sites.R. J. White - 1990 - Bioessays 12 (11):537-539.
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  26.  9
    S.o.S. - Simulation of Sight.Sara Matetich - 2023 - Aisthesis: Pratiche, Linguaggi E Saperi Dell’Estetico 15 (2):177-184.
    Each Site Specific is always and above all Time Specific, that is marked by Time and by the times from which it is generated, defined and set in a place. Space is a significant environment a work that works in the Work that re-means, in its transformation, the very connotations of performing action. To contain the never-ending process of meaning to which such a work would be subjected, it will be Time: that granitic categorial essence that philosophy, (...)
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  27.  17
    Permease on parade: Application of site‐directed mutagenesis to ion‐gradient driven active transport.H. Ronald Kaback - 1987 - Bioessays 7 (6):261-265.
    Oligonucleotide‐directed, sitespecific mutagenesis is being applied to the problem of ion‐gradient driven active transport with the lac permease as a model system. It has been shown that Arg‐302, His‐322 and Glu‐325, neighboring residues in putative transmembrane helices IX and X, play an important role in lactose‐coupled H+ translocation, possibly as components of a catalytic triad similar to that found in the serine proteases. In addition, Cys residues, long thought to be involved in the mechanism of the permease, are (...)
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  28. South Africa!S fruit processing industry: Competitiveness factors and the case for sector-specific industrial policy measures.Don Ross - manuscript
    The aim of this report is to consider feasible conditions under which South Africa!!" processed (e.g., canned and other packaged) fruit industry would be internationally competitive and a profitable site of investment, and therefore able to resume a pattern of growth from which it departed in the early part of the present decade. This is in service of the wider aim of identifying, in a subsequent phase of the project, appropriate industrial policy measures which Government might put in place (...)
     
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  29.  18
    Multi-sited Ethnography as a Middle Range Methodology for Contemporary STS.Christine Hine - 2007 - Science, Technology, and Human Values 32 (6):652-671.
    The paper draws its inspiration from the provocation which Merton offered sociology both to engage with empirical data and to perform analyses adequate to guide intervention beyond the particular case. Whilst contemporary STS is very different both in its models of theory and its forms of methodology, this paper suggests Merton's concerns with engagement and adequacy provide a useful way to interrogate current approaches. Specifically, the paper explores some recent anthropological conceptions of ethnographic fieldwork that have provided potent models for (...)
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  30.  33
    Art in situ or the Site as Art: A Japanese Reception of Contemporary Art.Hiroshi Uemura - 2020 - Iris 40.
    L’exposition d’art dans des paysages est devenu populaire au Japon, avec la multiplication récente de festivals d’art locaux. Dans ces festivals, qui attirent chacun des centaines de milliers de visiteurs, coexistent des œuvres hétérogènes. Certaines sont des sculptures autonomes, d’autres des installations qui se fondent dans le paysage, et d’autres encore sont des œuvres de type « art relationnel ». Bien que ces œuvres in situ affirment leur lien essentiel avec le site naturel rural et avec le corps du (...)
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  31.  23
    Site knowledge: in dynamic contexts.R. Black - unknown
    The PhD is concerned with the construction of site knowledge and how this is transformed into knowing where and how to intervene in a river system close to ecological collapse. It involves three overlapping topics: • Site knowledge and its impact upon the design process • Development of tools and techniques appropriate for working on a particular type of site condition: the threshold between land and water • Transitory: the impact of dynamic processes and events on inhabitation (...)
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  32.  61
    Trauma Site Museums and Politics of Memory.Patrizia Violi - 2012 - Theory, Culture and Society 29 (1):36-75.
    This article aims to analyse one specific type of memorial site that furnishes an indexical link to past traumatic events which took place in precisely these places. Such memorials will be defined here as trauma sites. It will be shown how the semiotic trait of indexicality produces unique meaning effects, forcing a reframing of the issue of representation, with all its aesthetic and ethical dimensions. In contrast to other forms of memorial site, trauma sites exist factually as (...)
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  33.  16
    The 'A rule' of mutagen specificity: A consequence of DNA polymerase bypass of non‐instructional lesions?Bernard S. Strauss - 1991 - Bioessays 13 (2):79-84.
    The replicative bypass of lesions in DNA and the induction of mutations by agents which react with DNA to produce damaged bases can be understood on the basis of a simple kinetic model. Bypass can be analyzed by separately considering three processes: (a) addition of a base opposite a lesion, (b) a proofreading excision process, and (c) a rate limiting elongation step. Adenine nucleotides are preferentially added opposite many lesions making it possible to predict mutational specificity. Replicative bypass (translesion synthesis) (...)
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  34.  17
    The Association Between Generalized and Specific Problematic Internet Use and Its Gender Differences Across Different Educational Levels.Yu Tian, Tengfei Zuo, Qianqian Sun, Lu Sun, Sheng Cao & Ningbo Qin - 2021 - Frontiers in Psychology 12.
    This study had two aims: to test the effect and the effect size of specific problematic Internet use [online shopping, online pornography, social network site usage, and Internet gaming] on generalized problematic Internet use and to reveal the gender differences in GPIU and SPIU for students from the elementary school level to the university level. In total, 5,215 Chinese students from four types of schools provided self-report data on demographic variables, online shopping, online pornography, SNS usage, Internet gaming, (...)
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  35.  24
    PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-beta precursor protein via a tissue-specific proximal regulatory element.D. K. Lahiri, B. Maloney, J. T. Rogers & Y. W. Ge - 2013 - Bmc Genomics 14:68.
    BACKGROUND: Alzheimer's disease is intimately tied to amyloid-beta peptide. Extraneuronal brain plaques consisting primarily of Abeta aggregates are a hallmark of AD. Intraneuronal Abeta subunits are strongly implicated in disease progression. Protein sequence mutations of the Abeta precursor protein account for a small proportion of AD cases, suggesting that regulation of the associated gene may play a more important role in AD etiology. The APP promoter possesses a novel 30 nucleotide sequence, or "proximal regulatory element" , at -76/-47, from the (...)
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  36.  21
    New enzymes for old: Redesigning the coenzyme and substrate specificities of glutathione reductase.Richard N. Perham, Nigel S. Scrutton & Alan Berry - 1991 - Bioessays 13 (10):515-525.
    A set of amino acid side chains that confer specificity for the coenzyme NADPH and the substrate glutathione in the flavoprotein disulphide oxidoreductase, glutathione reductase, has been identified. Systematic replacement of these amino acid residues in the coenzyme‐binding site switches the specificity of the enzyme from its natural strong preference for NADPH to a marked preference For NADH. The amino acids replaced all lie in a structural motif within the dinucleotide‐binding domain of the protein. Since this domain is a (...)
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  37.  7
    Nuclear domain 10, the site of DNA virus transcription and replication.Gerd G. Maul - 1998 - Bioessays 20 (8):660-667.
    Within the highly organized nuclear structure, specific nuclear domains (ND10) are defined by accumulations of proteins that can be interferon-upregulated, implicating ND10 as sites of a nuclear defense mechanism.Compatible with such a mechanism is the deposition of herpesvirus, adenovirus, and papovavirus genomes at the periphery of ND10. However, these DNA viruses begin their transcription at ND10 and consequently initiate replication at these sites, suggesting that viruses have evolved ways to circumvent this potential cellular defense and exploit it. Other ND10-associated (...)
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  38.  35
    The rise of food banks and the challenge of matching food assistance with potential need: towards a spatially specific, rapid assessment approach.Christopher M. Bacon & Gregory A. Baker - 2017 - Agriculture and Human Values 34 (4):899-919.
    In the United States, food banks served an estimated 46 million people in 2015. A combination of government policy reforms and political economic trends contributed to the rising numbers of individuals relying on private food assistance in the US, the United Kingdom and other high-income countries. Although researchers frequently map urban food environments, this project is one of the first to map private food assistance and potential need at the census-tract scale. We utilize Geographic Information Systems, demographic data, and food (...)
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  39.  56
    Exploring the Security of Information Sharing on Social Networking Sites: The Role of Perceived Control of Information.Nick Hajli & Xiaolin Lin - 2016 - Journal of Business Ethics 133 (1):111-123.
    Social networking sites have challenged ethical issues about users’ information security and privacy. SNS users are concerned about their privacy and need to control the information they share and its use. This paper examines the security of SNS by taking a look at the influence of users’ perceived control of information over their information-sharing behaviors. Employing an empirical study, this paper demonstrates the importance of perceived control in SNS users’ information-sharing behaviors. Specifically, perceived control has been found to be negatively (...)
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  40.  14
    Existing Site Conditions. Building Thermography and U-value Measurements. Case Study Tirana, Albania.Klodjan Xhexhi - 2023 - In Ecovillages and Ecocities. Bioclimatic Applications from Tirana, Albania. Switzerland: Springer Nature Switzerland AG. pp. 171-189.
    The stock of Albania buildings dating between 1955 and 1985 during the communist period is a very powerful and important footprint not only in the city of Tirana, Albania, but all over the country. This category of buildings is positioned mostly in the center of the city, within the inner historical ring of the city of Tirana. They are designed considering the mottos: standardization and typification representing the standards of the time. In the city of Tirana almost in every neighborhood (...)
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  41.  37
    Cross-Cultural and Site-Based Influences on Demographic, Well-being, and Social Network Predictors of Risk Perception in Hazard and Disaster Settings in Ecuador and Mexico.Eric C. Jones, Albert J. Faas, Arthur D. Murphy, Graham A. Tobin, Linda M. Whiteford & Christopher McCarty - 2013 - Human Nature 24 (1):5-32.
    Although virtually all comparative research about risk perception focuses on which hazards are of concern to people in different culture groups, much can be gained by focusing on predictors of levels of risk perception in various countries and places. In this case, we examine standard and novel predictors of risk perception in seven sites among communities affected by a flood in Mexico (one site) and volcanic eruptions in Mexico (one site) and Ecuador (five sites). We conducted more than (...)
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  42.  39
    Co-existing Notions of Research Quality: A Framework to Study Context-specific Understandings of Good Research.Liv Langfeldt, Maria Nedeva, Sverker Sörlin & Duncan A. Thomas - 2020 - Minerva 58 (1):115-137.
    Notions of research quality are contextual in many respects: they vary between fields of research, between review contexts and between policy contexts. Yet, the role of these co-existing notions in research, and in research policy, is poorly understood. In this paper we offer a novel framework to study and understand research quality across three key dimensions. First, we distinguish between quality notions that originate in research fields and in research policy spaces. Second, drawing on existing studies, we identify three attributes (...)
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  43.  4
    Using Google Sites to Improve Students' Learning Outcomes in Writing Ability: A Case on Teaching Language Education.Andoyo Sastromiharjo, Ratna Rintaningrum, Herman Herman, St Mislikhah, Everhard Markiano Solissa, Indri Lastriyani, Nanda Saputra & Ridwin Purba - forthcoming - Evolutionary Studies in Imaginative Culture:728-736.
    The ultimate purpose of this research is to investigate how far Google Sites can develop students' learning outcomes in writing ability. The need for English becomes one of the reasons why the requirement of universities in public consisting of speaking English. This research was conducted as a case study, with the objective of investigating the integration of Google Sites into language teaching strategies, specifically the design and execution of creating web-based instructional resources in Google Sites, and the benefits it provides (...)
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  44.  18
    Gegen Deutsches K.Z. Paradies. Thinking about Englishness on the Isle of Man during the Second World War.Dina Gusejnova - 2020 - History of European Ideas 46 (5):697-714.
    ABSTRACT This paper focuses on the intellectual output of the internees held captive as ‘enemy aliens’ on the Isle of Man during the Second World War. Looking at their interactions with local and national knowledge communities, including some Methodist priests who were responsible for introducing the internees to British political culture, it analyses how the social environment of internment created common intellectual experiences, which in turn led members of this involuntary community of displaced German-speaking scholars to form particular conceptions of (...)
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  45.  32
    Retroviral integration: Site matters.Jonas Demeulemeester, Jan De Rijck, Rik Gijsbers & Zeger Debyser - 2015 - Bioessays 37 (11):1202-1214.
    Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integration machinery is guided to particular chromatin contexts. As the viral integrase captures a local target nucleosome, specific contacts introduce fine‐grained biases in the integration site distribution. In vivo, the established (...)
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  46.  1
    Stories of Disaster as Sites of Mitigation: Knowledge Production and Affective Engagement in the Narrativization of Nuclear Incidents in Different Media.Martin Butler, Sina Farzin, Michael Fuchs, Anna-Katharina Hornidge & Uwe Schimank - forthcoming - Minerva:1-25.
    This article explores how nuclear disaster narratives have both been informed by and articulated collective images of risk and uncertainty since the 1980s. Drawing on ideas from classical and affective narratology that are framed by a perspective informed by the sociology of knowledge, we examine three variations of narrating nuclear disasters in different media: (1) sociologist Charles Perrow’s detailed analysis of the Three Mile Island accident in his popular science book _Normal Accidents_ (1984), (2) Svetlana Alexievich’s _Chernobyl Prayer_ (1997), a (...)
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    Determinants of Electronic Word-of-Mouth on Social Networking Sites About Negative News on CSR.Maria del Mar García-de los Salmones, Angel Herrero & Patricia Martínez - 2020 - Journal of Business Ethics 171 (3):583-597.
    Social network sites are a new communication channel to convey CSR information. They are interactive channels that let users participate, spread content and generate positive and negative electronic word-of-mouth about companies that can dramatically affect their reputation and future business. To identify the factors behind this behaviour, we designed a causal model to explain the intention to both comment on and share a negative corporate social responsibility news posted on Facebook. We included the following as explanatory variables: social consciousness, environmental (...)
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  48.  2
    Pushing the TAD boundary: Decoding insulator codes of clustered CTCF sites in 3D genomes.Haiyan Huang & Qiang Wu - 2024 - Bioessays 46 (10):2400121.
    Topologically associating domain (TAD) boundaries are the flanking edges of TADs, also known as insulated neighborhoods, within the 3D structure of genomes. A prominent feature of TAD boundaries in mammalian genomes is the enrichment of clustered CTCF sites often with mixed orientations, which can either block or facilitate enhancer–promoter (E‐P) interactions within or across distinct TADs, respectively. We will discuss recent progress in the understanding of fundamental organizing principles of the clustered CTCF insulator codes at TAD boundaries. Specifically, both inward‐ (...)
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    The polypeptide tunnel exit of the mitochondrial ribosome is tailored to meet the specific requirements of the organelle.Steffi Gruschke & Martin Ott - 2010 - Bioessays 32 (12):1050-1057.
    The ribosomal polypeptide tunnel exit is the site where a variety of factors interact with newly synthesized proteins to guide them through the early steps of their biogenesis. In mitochondrial ribosomes, this site has been considerably modified in the course of evolution. In contrast to all other translation systems, mitochondrial ribosomes are responsible for the synthesis of only a few hydrophobic membrane proteins that are essential subunits of the mitochondrial respiratory chain. Membrane insertion of these proteins occurs co‐translationally (...)
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    Commercial contract cheating provision through micro-outsourcing web sites.Thomas Lancaster - 2020 - International Journal for Educational Integrity 16 (1).
    As the contract cheating market has become more sophisticated and competition has intensified, the contract cheating industry has had to redevelop its approach to gain custom. The industry has developed new models of internal operation and providers are using more sophisticated techniques to reach potential customers. This paper discusses contract cheating industry workflows and introduces terminology to allow complexities of the industry to be more consistently discussed. Examples are provided throughout to indicate the scale and challenge of the contract cheating (...)
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