It is often claimed that the greatest value of the Bayesian framework in cognitive science consists in its unifying power. Several Bayesian cognitive scientists assume that unification is obviously linked to explanatory power. But this link is not obvious, as unification in science is a heterogeneous notion, which may have little to do with explanation. While a crucial feature of most adequate explanations in cognitive science is that they reveal aspects of the causal mechanism that produces the phenomenon to be (...) explained, the kind of unification afforded by the Bayesian framework to cognitive science does not necessarily reveal aspects of a mechanism. Bayesian unification, nonetheless, can place fruitful constraints on causal–mechanical explanation. 1 Introduction2 What a Great Many Phenomena Bayesian Decision Theory Can Model3 The Case of Information Integration4 How Do Bayesian Models Unify?5 Bayesian Unification: What Constraints Are There on Mechanistic Explanation?5.1 Unification constrains mechanism discovery5.2 Unification constrains the identification of relevant mechanistic factors5.3 Unification constrains confirmation of competitive mechanistic models6 ConclusionAppendix. (shrink)

Bayes nets are a powerful tool for researchers in statistics and artificial intelligence. This chapter demonstrates that they are also of much use for philosophers and psychologists interested in (Bayesian) rationality. To do so, we outline the general methodology of Bayes nets modeling in rationality research and illustrate it with several examples from the philosophy and psychology of reasoning and argumentation. Along the way, we discuss the normative foundations of Bayes nets modeling and address some of the methodological problems it (...) raises. (shrink)

Discussions about a replicability crisis in science have been driven by the normative claim that all of science should be replicable and the empirical claim that most of it isn’t. Recently, such crisis talk has been challenged by a new localism, which argues a) that serious problems with replicability are not a general occurrence in science and b) that replicability itself should not be treated as a universal standard. The goal of this article is to introduce this emerging strand of (...) the debate and to discuss some of its implications and limitations. I will in particular highlight the issue of demarcation that localist accounts have to address, i.e. the question of how we can distinguish replicable science from disciplines where replicability does not apply. (shrink)

In the past decade well-designed research studies have shown that the practice of collaborative philosophical inquiry in schools can have marked cognitive and social benefits. Student academic performance improves, and so too does the social dimension of schooling. These findings are timely, as many countries in Asia and the Pacific are now contemplating introducing Philosophy into their curricula. This paper gives a brief history of collaborative philosophical inquiry before surveying the evidence as to its effectiveness. The evidence is canvassed under (...) two categories: schooling and thinking skills; and schooling, socialisation and values. In both categories there is clear evidence that even short-term teaching of collaborative philosophical inquiry has marked positive effects on students. The paper concludes with suggestions for further research and a final claim that the presently-available research evidence is strong enough to warrant implementing collaborative philosophical inquiry as part of a long-term policy. (shrink)

The view known as animalism asserts that we are human animals—that each of us is an instance of the Homo sapiens species. The standard argument for this view is known as the thinking animal argument . But this argument has recently come under attack. So, here, a new argument for animalism is introduced. The animal ancestors argument illustrates how the case for animalism can be seen to piggyback on the credibility of evolutionary theory. Two objections are then considered and answered.

The life sciences are said to be in the midst of a replication crisis because a majority of published results are irreproducible, and scientists rarely replicate existing data. Here I argue that point 2 of this assessment is flawed because there is a hitherto unidentified form of replication in the experimental life sciences, which I call ‘microreplications’. Using a case study from biochemistry, I illustrate how MRs depend on a key element of experimentation, namely, experimental controls. I end by reflecting (...) on what MRs mean for the broader debate about the replication crisis. (shrink)

In 2015 scientists called for a partial ban on genome editing in human germline cells. This call was a response to the rapid development of the CRISPR–Cas9 system, a molecular tool that allows researchers to modify genomic DNA in living organisms with high precision and ease of use. Importantly, the ban was meant to be a trust-building exercise that promises a ‘prudent’ way forward. The goal of this paper is to analyse whether the ban can deliver on this promise. To (...) do so the focus will be put on the precedent on which the current ban is modelled, namely the Asilomar ban on recombinant DNA technology. The analysis of this case will show (a) that the Asilomar ban was successful because of a specific two-step containment strategy it employed and (b) that this two-step approach is also key to making the current ban work. It will be argued, however, that the Asilomar strategy cannot be transferred to human genome editing and that the current ban therefore fails to deliver on its promise. The paper will close with a reflection on the reasons for this failure and on what can be learned from it about the regulation of novel molecular tools. (shrink)

The rare condition known as dicephalus occurs when (prior to implantation) a zygote fails to divide completely, resulting in twins who are conjoined below the neck. Human dicephalic twins look like a two-headed person, with each brain supporting a distinct mental life. Jeff McMahan has recently argued that, because they instance two of us but only one animal, dicephalic twins provide a counterexample to the animalist's claim that each of us is identical with a human animal. To the contrary, I (...) argue that in cases of dicephalus it is obvious neither that there is one animal nor that there are two of us. Consequently, the animalist criterion does not straightforwardly apply to cases of dicephalus. I defend an account of dicephalus that is both sensitive to the complexity of twinning phenomena and not inconsistent with animalism. In my view, dicephalic twins are a borderline case of the concept HUMAN ANIMAL. I conclude with some speculative remarks concerning the normative import (if any) of my claim that dicephalic twins are a borderline case. (shrink)

The reported birth of genetically modified twins in late 2018 has given new fuel to debates about the ethics of germline genome editing (GGE). There is a broad consensus among stakeholders that clinical uses of GGE should be temporarily banned as the technology is not yet deemed safe for use in humans. However, the idea of a complete ban is dismissed by many based on the expectation that more research will eventually allow scientists to make the technology safe without having (...) to put humans at risk first. In this article, I will analyse this assumption and argue that it is undermined by recent developments in the postgenomic life sciences. In particular, I will argue that in a postgenomic view of germline editing a complete ban on specific uses of the technology is warranted, because the research needed to assess the safety of these interventions would not be morally defensible. (shrink)

We propose an action-oriented understanding of emotion. Emotions are modifications of a basic form of goal-oriented striving characteristic of human life. They are appetitive orientations: pursuits of the good, avoidances of the bad. Thus, emotions are not truly distinct from, let alone opposed to, actions -- as erroneously suggested by the classical understanding of emotions as 'passions'. In the present paper, we will outline and defend this broadly enactive approach and motivate its main claims. Our proposal gains plausibility from a (...) literature- and interview-based investigation of emotional changes characteristic of clinical depression. Much narrative evidence from patient reports points towards the conclusion that many of those changes might result from a catastrophic alteration of the basic form of goal-pursuit at the root of human emotionality. The experience of profound depression could in this respect be a kind of inverted image of non-pathological emotionality--a highly unnatural passivity, giving rise to a profound -- and quite horrifying -- sense of incapacity. (shrink)

Many historians of philosophy, with all their intended praise, let the philosophers speak mere nonsense. They do not guess the purpose of the philosophers.… They cannot see beyond what the philosophers actually said, to what they really meant to say.Mou Zongsan (1909–1995) is one of the key figures of contemporary New Confucianism (當代新儒家) who to this day remains largely unknown and grossly understudied in the West.1 This neglect by the Western academy contrasts sharply with the ever-growing output of literature by (...) Chinese and Taiwanese scholars in which Mou Zongsan emerges as one of the most discussed and most controversial Chinese philosophers of the twentieth century. Given this unfortunate East-West divide—as .. (shrink)

This article focuses on existential feelings. To begin with, it depicts how they differ from other affective phenomena and what type of intentionality they manifest. Furthermore, a detailed analysis shows that existential feelings can be subdivided, first, into elementary and nonelementary varieties, and second, into three foci of primary relatedness: oneself, the social environment, and the world as such. Eventually, five strategies of emotion regulation are examined with respect to their applicability to existential feelings. In the case of harmful existential (...) feelings, it turns out that none seems fitting except one, attentional deployment. (shrink)

Despite widespread support for the claim that death can harm the one who dies, debate continues over how to rescue this harm thesis (HT) from Epicurus’s challenge. Disagreements focus on two of the three issues that any defense of HT must resolve: the subject of death’s harm and the timing of its injury. About the nature of death’s harm, however, a consensus has emerged around the view that death harms a subject (when it does) by depriving her of the goods (...) life would’ve afforded had she continued living. This deprivation view of death’s harm (DV) derives some of its credibility from the general deprivation theory of which it is an instance: mortal harm is subject to the same kind of analysis plausibly given of other non-mortal harms. Furthermore, note that the weak formulation of HT—asserting only that death can inflict harm, not that it always or necessarily does—accommodates the intuition that instances of rational suicide and justifiable euthanasia present cases in which death fails to harm. DV is equipped to explain how in these cases the harms involved in continued existence outweigh the goods of which death deprives the subject. I agree that suicide can be rational and that euthanasia can be justifiable. Likewise I accept both HT and DV as far as they go. But they do not go far enough. Specifically, I argue here that death harms even those who die as a result of rational suicide or justifiable euthanasia; that death’s harm is neither undifferentiated nor wholly contingent, but multifaceted and partly necessary; that the necessary part of death’s harm is distinctive, inflicting a peculiar restriction on the autonomy of one who dies; and, regarding the timing and subject issues, that this restriction harm is inflicted on the antemortem subject prior to her death. (shrink)

There are various ways to reach a group decision on a factual yes–no question. One way is to vote and decide what the majority votes for. This procedure receives some epistemological support from the Condorcet Jury Theorem. Alternatively, the group members may prefer to deliberate and will eventually reach a decision that everybody endorses—a consensus. While the latter procedure has the advantage that it makes everybody happy, it has the disadvantage that it is difficult to implement, especially for larger groups. (...) Besides, the resulting consensus may be far away from the truth. And so we ask: Is deliberation truth-conducive in the sense that majority voting is? To address this question, we construct a highly idealized model of a particular deliberation process, inspired by the movie Twelve Angry Men, and show that the answer is ‘yes’. Deliberation procedures can be truth-conducive just as the voting procedure is. We then explore, again on the basis of our model and using agent-based simulations, under which conditions it is better epistemically to deliberate than to vote. Our analysis shows that there are contexts in which deliberation is epistemically preferable and we will provide reasons for why this is so. (shrink)

By reconstructing the teleological conceptions of Thomas Aquinas, Suarez, Descartes, Spinoza, and Leibniz, the author argues against the common view that mechanical philosophers in the Early Modern Period rejected natural teleology because of its association with an Aristotelian picture of the world. First, many thinkers in the Early Modern Period did not reject teleological explanations for natural phenomena. Second, many scholastic thinkers already believed that pure natural teleology was problematic because they held that authentic teleological explanations are only possible when (...) goals can be recognized.". (shrink)

Determining the knowledge that guides human judgments is fundamental to understanding how people reason, make decisions, and form predictions. We use an experimental procedure called ‘‘iterated learning,’’ in which the responses that people give on one trial are used to generate the data they see on the next, to pinpoint the knowledge that informs people's predictions about everyday events (e.g., predicting the total box office gross of a movie from its current take). In particular, we use this method to discriminate (...) between two models of human judgments: a simple Bayesian model (Griffiths & Tenenbaum, 2006) and a recently proposed alternative model that assumes people store only a few instances of each type of event in memory (MinK; Mozer, Pashler, & Homaei, 2008). Although testing these models using standard experimental procedures is difficult due to differences in the number of free parameters and the need to make assumptions about the knowledge of individual learners, we show that the two models make very different predictions about the outcome of iterated learning. The results of an experiment using this methodology provide a rich picture of how much people know about the distributions of everyday quantities, and they are inconsistent with the predictions of the MinK model. The results suggest that accurate predictions about everyday events reflect relatively sophisticated knowledge on the part of individuals. (shrink)

In the Groundwork of the Metaphysics of Morals, Kant explains a perfect duty as one that “admits no exception in favor of inclination”. An imperfect duty must then, in turn, be one which does admit such exceptions. However, according to Kant, all duties are valid without exception, and so there has been broad agreement among Kantians and Kant interpreters from the beginning that perfect duties cannot be characterized by exceptionless validity. I would thus like to argue in favor of a (...) different reading of Kant’s explanation. My thesis is that he uses the term ‘exception’ in quite different ways, as can be documented, for instance, in the Metaphysics of Morals and the Critique of Pure Reason. The term then has another meaning, and this is also the case in the passage in question in the Groundwork. (shrink)

François Jullien’s idea of landscape in Chinese philosophy and art is taken from the refinement of highly literate writers and artists, unrelated to the techniques of location that find good sites and make places in landscape. This article is based on a study of fengshui (Chinese geomancy). It argues that fengshui is a practice of identifying not things or beings but moments and circumstances of a client. It works with an epistemology of pattern recognition, which is based on observation and (...) experience but does not test the truth of the signs that are the means of recognizing patterns. This epistemology of pattern recognition is not peculiarly Chinese but can also be found in building, urban planning, and the art of medical diagnosis. (shrink)

According to a seminal paper by Barsalou , frames are attribute-value-matrices for representing exemplars or concepts. Frames have been used as a tool for reconstructing scientific concepts as well as conceptual change within scientific revolutions . In the frame-based representations of scientific concepts developed so far the semantic content of concepts is determined by a set of attribute-specific values. This way of representing semantic content works best for prototype concepts and defined concepts of a conceptual taxonomy satisfying the no-overlap principle. (...) In addition to the semantic content of prototype concepts and defined concepts, frames can also contain empirical knowledge that is represented as constraints between the values of the frame. Beside prototype concepts and defined concepts, theoretical concepts that are multiply operationalized play an important role in science. However, so far no frame-based representation of theoretical concepts has been proposed. In this paper, it will be shown that theoretical concepts can be represented by frames and that frame-based representations of prototype concepts and defined concepts have another structure than frame-based representations of theoretical concepts. In order to explicate this difference, we will develop a frame-based method for representing all three kinds of concepts by means of mathematical graph-theory. One important consequence will be that the constraints of a frame representing a theoretical concept are entailed by the structure of the frame, as opposed to a frame representing defined or prototype concepts. (shrink)

I consider whether the self-ascription theory can succeed in providing a tenseless (B-theoretic) account of tensed belief and timely action. I evaluate an argument given by William Lane Craig for the conclusion that the self-ascription account of tensed belief entails a tensed theory (A-theory) of time. I claim that how one formulates the selfascription account of tensed belief depends upon whether one takes the subject of selfascription to be a momentary person-stage or an enduring person. I provide two different formulations (...) of the self-ascription account of tensed belief, one that is compatible with a perdurantist account of persons and the other that is compatible with an endurantist account of persons. I argue that a self-ascription account of tensed beliefs for enduring subjects most plausibly involves the self-ascription of relations rather than properties. I argue that whether one takes the subject of self-ascription to be a momentary personstage or an enduring person, the self-ascription theory provides a plausible B-theoretic account of how tensed belief and timely action are possible. (shrink)

In September 1998 the Bundesrztekammer, i.e., the German Medical Association, published new principles concerning terminal medical care. Even before publication, a draft of these principles was very controversial, and prompted intense public debate in the mass media. Despite some of the critics' suspicions that the principles prepared the way for liberalization of active euthanasia, euthanasia is unequivocally rejected in the principles. Physician-assisted suicide is considered to violate professional medical rules. In leaving aside some of the notions customarily used in the (...) euthanasia debate, e.g., passive euthanasia, the principles emphasize the obligation of physicians to offer and the right of patients to receive palliative care. The principles explicitly list modalities of basic treatment that are indispensable in all cases, such as the obligation to satisfy hunger and thirst. This statement is meant to resolve the dispute on nutrition and hydration at the end of life, as it shifts the focus of care from maintaining physiological parameters to satisfying subjective needs. For patients in a persistent vegetative state, artificial feeding is held to be obligatory. Yet, the principles make reference to recent German jurisdiction which permit the stopping of artificial feeding if it is in accordance with the patient's presumed will. Additionally, the wording concerning this issue is found to remain unclear. Patients' autonomy is strengthened by explicitly welcoming advance directives as a means to ascertain patients' wills. The principles mark some changes compared to earlier documents. They deserve careful analysis and should be considered in the international debate on issues concerning the end of life. (shrink)

Often, the behavior of animals can be better explained and predicted, it seems, if we ascribe the capacity to have beliefs, intentions, and concepts to them. Whether we really can do so, however, is a debated issue. Particularly, Donald Davidson maintains that there is no basis in fact for ascribing propositional attitudes or concepts to animals. I will consider his and rival views, such as Colin Allen's three-part approach, for determining whether animals possess concepts. To avoid pure theoretical debate, however, (...) I will test these criteria using characteristic examples from ethology that depict a broad range of animal behavior. This will allow us to detect a series of gradations in animals' capacities, in the course of which we can think over what would count for or against an attribution of concepts and propositional attitudes to them in each single case. Self-conceit is our natural hereditary disease. Of all creatures man is the most wretched and fragile, and at once the most supercilious. ... It is by this conceit that man arrogates to himself ... divine properties, that he segregates himself from the mass of other creatures and raises himself above them .. (shrink)

Why the DNA‐containing organelles, chloroplasts, and mitochondria, are inherited maternally is a long standing and unsolved question. However, recent years have seen a paradigm shift, in that the absoluteness of uniparental inheritance is increasingly questioned. Here, we review the field and propose a unifying model for organelle inheritance. We argue that the predominance of the maternal mode is a result of higher mutational load in the paternal gamete. Uniparental inheritance evolved from relaxed organelle inheritance patterns because it avoids the spread (...) of selfish cytoplasmic elements. However, on evolutionary timescales, uniparentally inherited organelles are susceptible to mutational meltdown (Muller's ratchet). To prevent this, fall‐back to relaxed inheritance patterns occurs, allowing low levels of sexual organelle recombination. Since sexual organelle recombination is insufficient to mitigate the effects of selfish cytoplasmic elements, various mechanisms for uniparental inheritance then evolve again independently. Organelle inheritance must therefore be seen as an evolutionary unstable trait, with a strong general bias to the uniparental, maternal, mode. (shrink)

In the philosophy of science, the frame model is used in order to represent and analyze scientific concepts and conceptual change. However, the potential of the frame model is far from being fully exploited: Up to now, the frame model is only applied to a rather small set of different kinds of concepts and important advantages of the frame model for reconstructing and analyzing concepts have been neglected. In this article, we will essentially extend the frame model in the following (...) way: We will develop a frame-based approach for representing a comprehensive class of different kinds of concepts including conjunctively and disjunctively defined concepts, family resemblance concepts, prototype concepts, operationalized concepts, dual concepts integrating two different ways of concept determination, and theoretical concepts. In order to do so, we will define different kinds of frames with respect to the logical structure of the kind of concept that is represented by a particular frame. We will exemplify our approach by means of ten frames applied to standard cases of conceptual analyses in philosophy and cognitive science as well as to scientific concepts of political science, psychology, linguistics and physics. (shrink)

This paper reviews four leading strategies for addressing the problem of material constitution, along with some of the prominent objections faced by each approach. Sections include (1) "The Orthodox View: Coincident Objects," (2) "Dominant Kinds," (3) "Nihilism," (4) "Revising the Logic of Identity," and (5) "Future Research." Also included is an annotated bibliography.

Alongside science and law, argumentation is also of central importance in everyday life. But what characterizes a good argument? This question has occupied philosophers and psychologists for centuries. The theory of Bayesian argumentation is particularly suitable for clarifying it, because it allows us to take into account in a natural way the role of uncertainty, which is central to much argumentation. Moreover, it offers the possibility of measuring the strength of an argument in probabilistic terms. One way to do this, (...) implicit in much work, is to identify the strength of an argument with the degree to which the premises of the argument confirm the conclusion. We criticize this prima facie plausible proposal and suggest instead that the strength of an argument has something to do with how much the premises and the conclusion of the argument cohere with each other. This leads to a new probabilistic measure whose properties we examine in more detail. (shrink)

The parts-based engineering approach in synthetic biology aims to create pre-characterised biological parts that can be used for the rational design of novel functional systems. Given the context-sensitivity of biological entities, a key question synthetic biologists have to address is what properties these parts should have so that they give a predictable output even when they are used in different contexts. In the first part of this paper I will analyse some of the answers that synthetic biologists have given to (...) this question and claim that the focus of these answers on parts and their properties does not allow us to tackle the problem of context-sensitivity. In the second part of the paper, I will argue that we might have to abandon the notions of parts and their properties in order to understand how independence in biology could be achieved. Using Robert Cummins’ account of functional analysis, I will then develop the notion of a capacity and its condition space and show how these notions can help to tackle the problem of context-sensitivity in biology. (shrink)

Past anatomical dissection practice has received recent attention in the humanities and social science literature, especially in a number of popular format books. In these works, past ethically dubious dissection practices are again revisited, including stealing the dead for dissection. There are extremely simple, yet very important, lessons to be had in these analyses, including: do not exploit the dead and treat the dead with dignity, respect, and reverence. In this paper, we highlight that these principles apply not just to (...) anatomists but to all parties concerned with bodies for dissection, including journalists and authors from the humanities writing on anatomical dissection whether in the historical or modern-day context. Not too infrequently these same authors/publishers resort to sensationalist language in titles, text, and/or promotion blurbs in a bid to grab attention and sell books. These actions, yet again, exploit dissection subjects for commercial purposes. The use of insensitive and sensationalist language that is designed to shock, fails to set good precedent for young impressionable students and paints an entirely backward picture of modern-day anatomy for intending or existing donors and their families. We suggest that all who participate in anatomical endeavours should strive to do so with reverence toward the dead, including armchair journalists and humanities authors who, just like their hands-on anatomical colleagues, should employ dignified, sensitive, and respectful language that is not sensationalist. (shrink)

Der Transhumanismus versteht sich als kulturelle Bewegung und als interdisziplinärer Forschungsansatz mit dem Ziel der umfassenden Verbesserung des Menschen, d.h. seiner kognitiven, emotionalen und moralischen Fähigkeiten, mit technischen Mitteln. Der Transhumanismus stellt lebensweltlich grundlegende Grenzziehungen in Frage, z.B. der Grenze zwischen Natur und Technik, Mensch und Tier, Mensch und Maschine, Personen und Sachen, Wachsen und Eingreifen, Therapie und enhancement. Primäres Ziel dieses Bandes ist eine Kritik des Transhumanismus. Die Beiträge diskutieren seine impliziten Metaphysik, Anthropologie und Ethik: Ist das vom Transhumanismus (...) anvisierte Ziel metaphysisch möglich und auch technisch realisierbar? Ist die von ihm geforderte umfassende Technisierung der menschlichen Natur moralisch legitim und sozialethisch vertretbar? Ist die Selbstverbesserung des Menschen durch Überwindung seiner conditio humana überhaupt rational wünschenswert? Von der kritischen Durchleuchtung transhumanistischer Positionen soll eine aufklärerische Wirkung auf eine technikbegeisterte intellektuelle Öffentlichkeit ausgehen. (shrink)

A number of proposals exist concerning how to support the concept of roles at the level of programming languages. While some of these proposals indeed exhibit very promising properties, the concept of roles has not found its way into mainstream programming languages. We argue that this is due to the richness of the concept of roles and the fact that each existing proposal focuses on some aspects of roles while neglecting others. We present the programming language ObjectTeams/Java and using the (...) categories of Steimann (2000) we demonstrate that this language covers more aspects of roles than previous approaches. We suggest that a thoroughly defined programming language featuring roles may contribute to a better understanding also in other fields using roles. (shrink)

Let me first state that I like Antti Revonsuo’s discussion of the various methodological and interpretational problems in neuroscience. It shows how careful and methodologically reflected scientists have to proceed in this fascinating field of research. I have nothing to add here. Furthermore, I am very sympathetic towards Revonsuo’s general proposal to call for a Philosophy of Neuroscience that stresses foundational issues, but also focuses on methodological and explanatory strategies.2 In a footnote of his paper, Revonsuo complains – as many (...) others do today – about what is sometimes called “physics imperialism”. This is the view that physics dominates the philosophy of science. I am not sure if this is still the case nowadays, but it is certainly historically correct that almost all work in the field of methodology centered around cases from physics. Although this has been changing, there are still plenty of special sciences philosophers did not worry about much. Admittedly, I am myself a trained physicist and not a neuroscientist and will therefore probably be biased negatively. As it is, I will discuss some examples from physics in order to illustrate my points. (shrink)