This paper considers the applicability of standard accounts of causation to living systems. In particular it examines critically the increasing tendency to equate causal explanation with the identification of a mechanism. A range of differences between living systems and paradigm mechanisms are identified and discussed. While in principle it might be possible to accommodate an account of mechanism to these features, the attempt to do so risks reducing the idea of a mechanism to vacuity. It is proposed that the solution (...) to this problem requires the development of a philosophical account of process adequate to apply to living systems. (shrink)

[John Dupré] This paper attacks some prominent contemporary attempts to provide reductive accounts of ever wider areas of human behaviour. In particular, I shall address the claims of sociobiology (or evolutionary psychology) to provide a universal account of human nature, and attempts to subsume ever wider domains of behaviour within the scope of economics. I shall also consider some recent suggestions as to how these approaches might be integrated. Having rejected the imperialistic ambitions of these approaches, I shall briefly (...) advocate a more pluralistic approach to the understanding of human behaviour, and one which leaves some space for the possibility of genuine human autonomy. /// [John O'Neill] One response to Dupré's criticism of rational choice theory's unifying aspirations is that it is aimed at over-ambitious versions of the theory. Immodesty about the scope of rational choice theory may look more plausible given suitable modesty in assumptions about the rational agent. The paper examines problems with one immodest version of the theory-public choice theory-and show how these shed light on problems in modest versions employing minimal assumptions about the preference structure of rational agents. However, while rational choice theory may fail in its unifying ambitions, I argue those aspirations are defensible. (shrink)

With this manifesto, John Dupré systematically attacks the ideal of scientific unity by showing how its underlying assumptions are at odds with the central conclusions of science itself.

John Dupr explores recent revolutionary developments in biology and considers their relevance for our understanding of human nature and society. He reveals how the advance of genetic science is changing our view of the constituents of life, and shows how an understanding of microbiology will overturn standard assumptions about the living world.

John Dupré explores the ways in which we categorize animals, including humans, and comes to refreshingly radical conclusions. He opposes the idea that there is only one legitimate way of classifying things in the natural world, the 'scientific' way. The lesson we should learn from Darwin is to reject the idea that each organism has an essence that determines its necessary place in the unique hierarchy of things. Nature is not like that: it is not organized in a single (...) system. For instance, there is no universal principle by which organisms can be sorted into species. We are obliged to accept that different classificatory schemes are equally valid, and to take a pluralistic view of biology and the human sciences. These provocative and readable essays move on to discuss a set of contentious topics relating to human nature. To start with, Dupré argues that the concept of a universal human nature should be rejected. He questions the relevance of evolution to explanation of human behaviour, and casts doubt on the concept of normality in human behaviour. He shows that misunderstanding of biology and evolution has lead to widespread misconceptions about human sex and gender-in particular, about sexual behaviour and gender roles. The books concludes with a pair of essays about the differences between humans and animals, which may not be quite so clear-cut as we think. (shrink)

A ciência, inicialmente prevista para servir ao homem, se desvia de sua finalidade original e começa a ameaçá-lo. A questão se põe, então, com acuidade em saber qual homem corresponderia à ciência de hoje. Face à visão fortemente cientificista do homem, caberia, entre outros, recorrer a Charles de Bovelles (1479-1566), a quem se deve recorrer para retornar a um conhecimento de si, que é o conhecimento da atividade de sua alma que, por seu turno, deve conhecer o corpo. A philautia (...) (amor de sua condição humana) torna-se, pois, o ponto de partida de uma antropologia filosófica sapiencial em uma perspectiva de conhecimento de si, pelo “sistere in homine” (permanecer no homem) para uma verdadeira ipsologia (discurso de si sobre si). O humanismo encontrado deve, então, se abrir, segundo Bovelles, à transcendência, a este traço de Deus sempre no homem que a ciência busca apagar. Palavras-chave: Homem - científico - Ipsologia - Conhecimento - Philautia - Humanismo. (shrink)

The recent proliferation of new data and technologies enables increasingly finer personalization of products and prices in every domain. In insurance, this revives and enlarges old debates around fairness that have never been completely settled. We will argue that the commonly accepted “actuarial fairness” as based on the “individual cost of risk” derives in fact from a conflation: while it indicates the average cost for a group of insureds from the perspective of an insurance company—and is therefore sound from a (...) business profitability viewpoint—it is arguable whether it represents the “fair price” for the individual insured. We first show in a historical perspective the intertwinement of conceptions of fairness with knowledge, in order to point to the alternative to actuarial fairness for insurance. We then describe the intrinsic difference between the insured and the insurer when underwriting an insurance contract. Finally, we build on this distinction to discuss the meaning of fairness in insurance prices. We thus hope to re-center the debate around insurance fairness on its underlying solidarity mechanisms rather than technical and actuarial considerations. (shrink)

We address three fundamental questions: What does it mean for an entity to be living? What is the role of inter-organismic collaboration in evolution? What is a biological individual? Our central argument is that life arises when lineage-forming entities collaborate in metabolism. By conceiving of metabolism as a collaborative process performed by functional wholes, which are associations of a variety of lineage-forming entities, we avoid the standard tension between reproduction and metabolism in discussions of life – a tension particularly evident (...) in discussions of whether viruses are alive. Our perspective assumes no sharp distinction between life and non-life, and does not equate life exclusively with cellular or organismal status. We reach this conclusion through an analysis of the capabilities of a spectrum of biological entities, in which we include the pivotal case of viruses as well as prions, plasmids, organelles, intracellular and extracellular symbionts, unicellular and multicellular life-forms. The usual criterion for classifying many of the entities of our continuum as non-living is autonomy. This emphasis on autonomy is problematic, however, because even paradigmatic biological individuals, such as large animals, are dependent on symbiotic associations with many other organisms. These composite individuals constitute the metabolic wholes on which selection acts. Finally, our account treats cooperation and competition not as polar opposites but as points on a continuum of collaboration. We suggest that competitive relations are a transitional state, with multi-lineage metabolic wholes eventually outcompeting selfish competitors, and that this process sometimes leads to the emergence of new types or levels of wholes. Our view of life as a continuum of variably structured collaborative systems leaves open the possibility that a variety of forms of organized matter – from chemical systems to ecosystems – might be usefully understood as living entities. (shrink)

It has increasingly been recognised that units of biological classification cannot be identified with the units of evolution. After briefly defending the necessity of this distinction I argue, contrary to the prevailing orthodoxy, that species should be treated as the fundamental units of classification and not, therefore, as units of evolution. This perspective fits well with the increasing tendency to reject the search for a monistic basis of classification and embrace a pluralistic and pragmatic account of the species category. It (...) also provides a diagnosis of the paradoxical but popular idea that species are individuals: Species are not individuals, but the units of evolution are. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 42.2 (2004) 220-221 [Access article in PDF] Clyde Lee Miller. Reading Cusanus: Metaphor and Dialectic in a Conjectural Universe. Washington, D.C.: Catholic University of America Press, 2003. Pp. viii + 276. Cloth, $64.95. In an age where the idea of postmodernity gains more and more ground, the period of postmodern thinking has turned into a major challenge to the human mind. Whereas the (...) project of modernity revokes itself through the contradictions it has generated, the need to find new perspectives makes us wonder what happened in the 15th century when the Renaissance paved the way to modernity and still contained seeds of alternative developments which for one reason or another did not get a chance to germinate. This is an invitation to concentrate on the work of Nicholas of Cusa (1401-1464) as one of the major Renaissance thinkers.Miller's book is an attempt to promote the understanding of Cusanus by a close reading of six of the major works of this author. In reading these works he focuses on Cusan thought both as this thought presents itself in these works, and as it appears against the background of traditional philosophy, especially when seen in the light of the Neoplatonic tradition.The works in question are the books On Learned Ignorance (De docta ignorantia) and On Conjectures (De coniecturis), aptly presented under the title: "Envisiong the Whole," and "Conjecturing Oneness and Otherness" respectively. The remaining four works concern the The Layman: About Mind (Idiota de mente) in which Cusanus develops his understanding of the mind and of intellectual authenticity; The Vision of God (De visione Dei), a treatise on mystical theology and an invitation to enter the divine mystery through a combination of prayer and reflection; On the Not Other (De non aliud), a highly speculative work on divine immanence and transcendence; and The Hunt for Wisdom (De venatione sapientiae) in which Cusanus gives an account of his philosophy by connecting it with the metaphor of a hunt in ten different fields. [End Page 220]Miller begins his book with an Introduction in which he outlines his approach to Cusanus, taking the cue from Plato's image of the divided line with its emphasis on the dialectical distinction between noesis (intellect) and dianoia (reason), and from the dialogue On the Hidden God (De Deo abscondito), a brief discussion between a Heathen and a Christian in which Cusanus connects the theme of learned ignorance with the act of adoration. The distinction between reason and intellect is important because the work of Cusanus is a continuous effort to cope with the meaning of distinctions and their impact on our ways of thinking. The reference to the dialogue is significant because this text clearly indicates that the quest for God is the central issue in the thought of Cusanus, and that the notion of ignorance is actually connected with the theoretical and practical meaning of God.In his discussion of the six works Miller follows the text of Cusanus which he presents in the form of argumentative summaries and complementary reflections. His presentation is lucid and to the point. In his reflections on the text and context of Cusan thought he gives valuable insights into the historical position of Cusanus and the manner in which Nicholas appropriated and transformed traditional ways of thinking. At the same time Miller keeps track of the reception of Cusanus by contemporary scholarship and the various interpretations it has to offer.The book ends with a "reprise" of the previous chapters which provides "an overall perspective on Nicholas' thought and its main themes and proposals" (241). The central elements of this perspective are "the metaphysics of the Infinite and the finite" (242) and the doctrine of perspectival relations as it has been developed in De coniecturis. What connects them with one another finds expression in the distinction (and transition) between explanatory and exploratory metaphors (252); that is, between metaphors such as "image-exemplar" and "unfolding-enfolding," which provide explanatory structures for the interpretation of reality, and metaphors such... (shrink)

Comment expliquer que tant d'humains, en ce début de XXIe siècle, accordent encore foi aux discours des religions, que ce soit une religion chrétienne, musulmane ou juive? Possèdent-elles des vérités plus assurées que celles des sciences humaines ou maintiennent-elles leurs fidèles dans l'ignorance, de peur que ceux-ci ne quittent le bateau amiral des églises, des mosquées ou des synagogues? Que proposent-elles de si séduisant pour que l'on sente le besoin de suivre aveuglément leurs enseignements et que des croyants soient prêts (...) à mourir ou à occire pour elles? « Au moment où le créationnisme devient de plus en plus présent dans le cursus académique et où le programme Ethique et culture religieuse, enseigné à nos jeunes dans nos écoles, fait l'apologie du religieux et banalise la superstition, ce livre de Marcel Sylvestre a de quoi nous faire réfléchir sur l'importance à accorder à la raison. » Extrait de la préface de Louise Mailloux. (shrink)

Metagenomics is an emerging microbial systems science that is based on the large-scale analysis of the DNA of microbial communities in their natural environments. Studies of metagenomes are revealing the vast scope of biodiversity in a wide range of environments, as well as new functional capacities of individual cells and communities, and the complex evolutionary relationships between them. Our examination of this science focuses on the ontological implications of these studies of metagenomes and metaorganisms, and what they mean for common (...) sense and philosophical understandings of multicellularity, individuality and organism. We show how metagenomics requires us to think in different ways about what human beings are and what their relation to the microbial world is. Metagenomics could also transform the way in which evolutionary processes are understood, with the most basic relationship between cells from both similar and different organisms being far more cooperative and less antagonistic than is widely assumed. In addition to raising fundamental questions about biological ontology, metagenomics generates possibilities for powerful technologies addressed to issues of climate, health and conservation. We conclude with reflections about process-oriented versus entity-oriented analysis in light of current trends towards systems approaches. (shrink)

This chapter contains sections titled: Introduction: No Need for Special Biological Laws? The Reductionist Principle Strong Emergence Complex Relations in Biology A Misinformed Slogan and Its Contributions Genes Causation Systems Biology Metaphysical Coda Postscript: Counterpoint Acknowledgments Notes References.

This collection of essays explores the metaphysical thesis that the living world is not made up of substantial particles or things, as has often been assumed, but is rather constituted by processes. The biological domain is organised as an interdependent hierarchy of processes, which are stabilised and actively maintained at different timescales. Even entities that intuitively appear to be paradigms of things, such as organisms, are actually better understood as processes. Unlike previous attempts to articulate processual views of biology, which (...) have tended to use Alfred North Whitehead’s panpsychist metaphysics as a foundation, this book takes a naturalistic approach to metaphysics. It submits that the main motivations for replacing an ontology of substances with one of processes are to be found in the empirical findings of science. Biology provides compelling reasons for thinking that the living realm is fundamentally dynamic, and that the existence of things is always conditional on the existence of processes. The phenomenon of life cries out for theories that prioritise processes over things, and it suggests that the central explanandum of biology is not change but rather stability, or more precisely, stability attained through constant change. This edited volume brings together philosophers of science and metaphysicians interested in exploring the consequences of a processual philosophy of biology. The contributors draw on an extremely wide range of biological case studies, and employ a process perspective to cast new light on a number of traditional philosophical problems, such as identity, persistence, and individuality. (shrink)

Humans are a kind of animal, and it is a natural and sensible idea that the way to understand what it is for a human person to persist over time is to reflect on what it is for an animal to persist. This paper accepts this strategy. However, especially in the light of a range of recent biological findings, the persistence of animals turns out to be much more problematic than is generally supposed. The main philosophical premise of the paper (...) is that living systems generally are best treated as processes rather than things. These processes prove to be so complexly intertwined and interdependent, that there is no unique, objective way of distinguishing the individuals from which they are composed. For this reason the animalist perspective, it is argued, problematizes as much as it resolves the problem of personal identity. Traditional concerns with responsibility and reactive attitudes provide an intelligible and defensible motivation for distinguishing the individuals we standardly assume as the explanandum in these discussions. But, from a biological point of view, the underlying individualism is a contingent perspective, as much justified by these concerns as providing an objective grounding for them. (shrink)

Dans l'impossibilite de s'instaurer ex nihilo, toute societe doit definir la nature des rapports que ses valeurs, ses normes, ses institutions et ses moeurs actuelles entretiennent avec celles qui gouvernaient son passe. Ces rapports se situent entre deux poles: celui de la reconduction et de la reproduction les plus fideles d'une part; celui de la rupture et de l'arrachement d'autre part. Les societes voisines du premier pole seront qualifiees de traditionnelles; celles plus proches du second seront appelees modernes. On reservera (...) le qualificatif de traditionalistes aux societes ou sous-groupes sociaux qui, au sein du monde moderne, veulent ouvertement, sinon restaurer, du moins rester inconditionnellement fideles a des principes, regles et modes de vie subvertis par la dynamique de la modernite. Apres avoir examine la polysemie de la tradition et du rapport a la tradition, l'ouvrage etudie en detail trois cas particuliers de la dialectique entre tradition et modernite la secularisation du christianisme et les mutations contemporaines des croyances et pratiques religieuses; la tension entre contractualisme et traditionalisme dans la constitution et les manifestations de l'appartenance nationale republicaine; la tradition du nouveau dans les arts plastiques. (shrink)

This chapter defends a pluralistic view of science: the various projects of enquiry that fall under the general rubric of science share neither a methodology nor a subject matter. Ontologically, it is argued that sciences need have nothing in common beyond an antipathy to the supernatural. Epistemically one central virtue is defended, empiricism, meaning just that scientific knowledge must ultimately be answerable to experience. Prima facie science is as diverse as the world it studies; and rejection of this prima facie (...) diversity in favour of a spurious aspiration to unity is grounded in a priori assumption not experience. Disunity, however, does not mean disconnectedness, and the connections between different areas of knowledge are an important theme in the book. (shrink)

Recent molecular biology has seen the development of genomics as a successor to traditional genetics. This paper offers an overview of the structure, epistemology, and history of contemporary genomics. A particular focus is on the question to what extent the genome contains, or is composed of, anything that corresponds to traditional conceptions of genes. It is concluded that the only interpretation of genes that has much contemporary scientific relevance is what is described as the "developmental defect" gene concept. However, developmental (...) defect genes typically only correspond to general areas of the genome and not to precise chemical structures . The parts of the genome to be identified for an account of the processes of normal development are highly diverse, little correlated with traditional genes, and act in ways that are highly dependent on the cellular and higher level environment. Despite its historical development out of genetics, genomics represents a radically different kind of scientific project. (shrink)

In an earlier paper (Dupré 1984), I criticized a thesis sometimes defended by theorists of probabilistic causality, namely, that a probabilistic cause must raise the probability of its effect in every possible set of causally relevant background conditions (the "contextual unanimity thesis"). I also suggested that a more promising analysis of probabilistic causality might be sought in terms of statistical relevance in a fair sample. Ellery Eells (1987) has defended the contextual unanimity thesis against my objections, and also raised (...) objections of his own to my positive claims. In this paper I defend and amplify both my objections to the contextual unanimity thesis and my constructive suggestion. (shrink)

This paper presents a brief response to Robert A. Wilson's critical discussion of Promiscuous Realism [1996]. I argue that, although convergence on a unique conception of species cannot be ruled out, the evidence against such an outcome is stronger than Wilson allows. In addition, given the failure of biological science to come up with a unique and privileged set of biological kinds, the relevance of the various overlapping kinds of ordinary language to the metaphysics of biological kinds is greater than (...) Wilson admits. (shrink)

Contrary to one possible interpretation of my title, this paper will not advocate any scepticism or ontological deflation. My concern will rather be with how we should best think about a realm of phenomena the existence of which is in no doubt, what has traditionally been referred to as the genetic. I have no intention of questioning a very well established scientific consensus on this domain. It involves the chemical DNA, which resides in almost all our cells, which is capable (...) of producing copies of itself that accurately reproduce a very long sequence of components, and which plays a role in the physiology of the cell which in certain basic respects is quite well understood. This substance has also achieved a remarkable iconic status in contemporary culture. It is seen as fundamental to personal identity both in the practical sense of providing a criterion of identity through DNA testing, and in the much deeper sense of being seen as, somehow, defining who we are. The latter role is illustrated, for example, by the recent debate about the right of children conceived by sperm donation to know who are their fathers. Such people, it is passionately argued, must be able to find out where they came from, who they really are. On a daily basis we are confronted with claims about the discovery of the genetic basis of—or in fact very often the ‘gene for’—all manner of psychological and physical characteristics, and all kinds of disorders. This holds out apparent possibilities. (shrink)

No aspect of Marx’s theory has received more attention in recent decades than the dialectical method. Yet, Western interpreters have mainly restricted the discussion to those early writings in which Marx explicitly confronts Hegel’s philosophy, while socialist commentators often hesitate to subject Marx’s mature writings to fundamental questioning. In the present contribution I propose to raise a number of questions concerning the dialectical method as used in Marx’s later works and as interpreted in those of his principal followers. I realize (...) that there may be a substantial difference between the two, yet since the latter, correctly or incorrectly, explicate a text which frequently demands further justification, they must be consulted. My purpose with this task is hermeneutical rather than critical. I feel that, despite the existing bulk of Marxist literature, we still have not read Marx attentively enough to be ready for a decisive critique of his work. My own critical remarks pretend to do no more than to allow the text to reveal its own meaning within its total context. They are part of that internal criticism without which there can be no true hermeneutic. (shrink)

Much scientific thinking and thinking about science involves assumptions that there is a deep and pervasive order to the world that it is the business of science to disclose. A paradigmatic statement of such a view can be found in a widely discussed paper by a prominent economist, Milton Friedman (a paper which will be discussed in more detail shortly): A fundamental hypothesis of science is that appearances are deceptive and that there is a way of looking at or interpreting (...) or organizing the evidence that will reveal superficially disconnected and diverse phenomena to be manifestations of a more fundamental and relatively simple structure. (1953/1984, p.231) On the other hand, the person sometimes described as the father of modern science, Francis Bacon, wrote: The human understanding is of its own nature prone to suppose the existence of more order and regularity in the world than it finds. And though there be many things in nature which are singular and unmatched, yet it devises for them conjugates and relatives which do not exist. (1620/1960, p. 50). (shrink)