This work is a self-contained elementary exposition of the theory of recursive functionals, that also includes a number of advanced results.

Prior research shows adults believe objects exist for specialised purposes. This “one tool, one function” cognitive bias promotes efficient mastery of artefact function but could mean indiv...

I introduce functional powers, i.e., causal powers that play the role of functions. In the first section, I characterize functions and present some desiderata for a good theory of functions. In the second section, I make some assumptions about the ontology of powers, teleology and structures-that will be helpful in order to ground my account of functional powers. In the third section, sixteen different types of functional powers are examined. All such types of functional powers will exhaustively contribute to performing (...) all the ontological and explanatory tasks that may be attributed to functions. Finally, in the fourth section, it is shown how my account of functions as functional powers satisfies all the desiderata presented at the outset. (shrink)

The topic of the paper is the notion of intuition in Descartes’ philosophy and its epistemic functions. Descartes introduces his notion of intuition in the context of a description of his method and process of knowing and doing science. Intuition is a significant component of this process. I intend to show that the main epistemic functions of intuition in Descartes’ philosophy are differentiated. Intuition is essential not only in the context of justification (the Cartesian synthetic method of proof) but also (...) and especially in the context of discovery (the Cartesian analytic method of discovery). It plays not only a role in the foundation of cogito but also on different stages of constructing the system of knowledge. Intuition has important functions in grasping simple natures, forming primary concepts, comprehending complex natures, forming primary propositions (including primary principles), and capturing relationships between them and building deductive reasoning (the role of intuition in deduction). Hence, intuition is the foundation for all primary stages of producing knowledge. It is active and important element of pure thinking (a priori) in human knowledge, and science. It fulfils these functions due to its specific epistemic properties. I also argue that intuition is not an autonomous and complete type of knowledge. Nor is it an intuitive thesis, but rather the basis of a justification for theses (including cogito). (shrink)

The eukaryotic nucleosome, the basic unit of chromatin, is thermodynamically stable and plays critical roles in the cell, including the maintenance of DNA topology and regulation of gene expression. At its C2 axis of symmetry, the nucleosome exhibits a domain that can coordinate divalent metal ions. This article discusses the roles of the metal‐binding domain in the nucleosome structure, function, and evolution.

Function talk is a constant across different life sciences. From macro-evolution to genetics, functions are mentioned everywhere. For example, a limb’s function is to allow movement and RNA polymerases’ function is to transcribe DNA. Biochemistry is not immune from such a characterization; the biochemical world seems to be a chemical world embedded within biological processes. Specifically, biochemists commonly ascribe functions to biomolecules and classify them accordingly. This has been noticed in the recent philosophical literature on biochemical kinds. But while a (...) lot has been written on biological and psychological functions, little has been said explicitly about biochemical fuctions. Here, I explore functional attribution to biochemical molecules. I argue that if we accept this attribution, then biochemical functions are constituted by chemical dispositional properties that causally contribute to selected biological processes. In section 2, I discuss the controversy concerning the characterization of biochemical functions. In section 3, I consider whether a biological or a chemical under- standing of function can be applied to biochemical functions, illustrating the account with the example of vitamin B12. The result is that none of the theories on their own provides an adequate characterization. In section 4, I present an account of biochemical functions. In section 5, I assess this account taking into consideration common requirements for a theory of functions and an objection. (shrink)

In this paper I defend an etiological theory of biological functions (according to which the proper function of a trait is the effect for which it was selected by natural selection) against three objections which have been influential. I argue, contrary to Millikan, that it is wrong to base our defense of the theory on a rejection of conceptual analysis, for conceptual analysis does have an important role in philosophy of science. I also argue that biology requires a normative notion (...) of a "proper function", and that a normative notion is not ahistorical. (shrink)

We study the complexity of (finitely-valued and transfinitely-valued) Euclidean functions for computable Euclidean domains. We examine both the complexity of the minimal Euclidean function and any Euclidean function. Additionally, we draw some conclusions about the proof-theoretical strength of minimal Euclidean functions in terms of reverse mathematics.

In this paper, I identify a central problem for conceptual engineering: the problem of showing concept-users why they should recognise the authority of the concepts advocated by engineers. I argue that this authority problem cannot generally be solved by appealing to the increased precision, consistency, or other theoretical virtues of engineered concepts. Outside contexts in which we anyway already aim to realise theoretical virtues, solving the authority problem requires engineering to take a functional turn and attend to the functions of (...) concepts. But this then presents us with the problem of how to specify a concept’s function. I argue that extant solutions to this function specification problem are unsatisfactory for engineering purposes, because the functions they identify fail to reliably bestow authority on concepts, and hence fail to solve the authority problem. What is required is an authoritative notion of conceptual function: an account of the functions of concepts which simultaneously shows why concepts fulfilling such functions should be recognised as having authority. I offer an account that meets this combination of demands by specifying the functions of concepts in terms of how they tie in with our present concerns. (shrink)

What is the function of morality? On this question, something approaching a consensus has recently emerged. Impressed by developments in evolutionary theory, many philosophers now tell us that the function of morality is to reduce social tensions, and to thereby enable a society to efficiently promote the well-being of its members. In this paper, I subject this consensus to rigorous scrutiny, arguing that the functional hypothesis in question is not well supported. In particular, I attack the supposed evidential relation between (...) an evolutionary genealogy of morals and the functional hypothesis itself. I show that there are a great many functionally relevant discontinuities between our own culture and the culture within which morality allegedly emerged, and I argue that this seriously weakens the inference from morality’s evolutionary history to its present-day function. (shrink)

This article locates Lonergan’s call for a new political economy within a larger project, the “education of liberty,” one aim of which is to have large numbers of producers and consumers voluntarily and intelligently adapting their economic decisions to the rhythms of the economy. Part I of the article describes several basic obstacles to such adaptations, including a type of economic realism that assumes “rational agency” in the marketplace is equivalent to the pursuit of perceived self-interest. How are any of (...) these obstacles to be overcome? The promise of functional specialization is to take what is best in the past and to apply it in future efforts to improve the human condition. Thus, Part II of the article summarizes this author’s understanding of the eight functional specialties, and Part III singles out an underdeveloped understanding of rational agency as the focus of an experiment in applying the functional specialties to one obstacle to the education of liberty. The experiment is no more than an invitation to others who may wish to exploit the promise of functional specialization. Leading questions under the eight headings identify parts of possible collaborative projects. [The second article by the same author in this issue of the journal provides an exercise in the fourth specialty of dialectic in response to this invitation.]. (shrink)

Comparisons between modally and amodally completed regions show that perceptual filling-in is not merely the ignoring of absences. Illusory filled-in colour arises for modal completion, but not for amodal completion in comparable displays. We find that attention spreads automatically to modally but not amodally completed regions from their inducers, revealing a functional effect of filled-in colour.

It will be seen how in place of the wealth and poverty of political economy come the rich human being and rich human need. The rich human being is simultaneously the human being in need of totality of human life-activities — the man in whom his own realization exists as an inner necessity, as need. Marx, Economic and Philosophical Manuscripts of 1844 Svetaketu abstained from food for fifteen days. Then he came to his father and said, `What shall I say?' (...) The father said: `Repeat the Rik, Yagus, and Saman verses.' He replied, `They do not occur to me, Sir.' The father said to him... `Go and eat! Then wilt thou understand me.' Then Svetaketu ate, and afterwards approached his father. And whatever his father asked him, he knew it all by heart.... After that, he understood what his father meant when he said: `Mind, my son, comes from food, breath from water, speech from fire.' He understood what he said, yea, he understood it. Chandogya-Upanishad, VI Prapathaka, 7 Kanda When you love a man you want him to live and when you hate him you want him to die. If, having wanted him to live, you then want him to die, this is a misguided judgment. `If you did not do so for the sake of riches, you must have done so for the sake of novelty.' Confucius, Analects, Book 12. 10. (shrink)

This article studies the function of the verbs seem and parecer with an evidential meaning in early medical writing in a time span of two centuries. The texts for analysis are excerpted from the Corpus of Early Modern English Medical Texts in the case of English and the Corpus diacrónico del español in the case of Spanish. My hypothesis is that the forms seem and parecer are mainly evidential rather than epistemic, as suggested in the works of Johansson and Aijmer, (...) since they primarily report on the speaker’s role in the formulation of predication. In this sense, the use of seem shows the way in which information has been obtained. Source of knowledge identification and attribution are important in medical prose because writers tend to make manifest that their information is based on demonstrable grounds, including inferential processes. My notion of evidentiality draws on the work of Cornillie and is essentially disjunctive. This means that the association of mode/source of knowledge with varying degrees of certainty and truth does not always take place. This study also allows for cross-cultural and cross-linguistic conclusions in terms of frequency, motivation and use of these evidential verbs in historical texts. (shrink)

A common misunderstanding of the selected effects theory of function is that natural selection operating over an evolutionary time scale is the only functionbestowing process in the natural world. This construal of the selected effects theory conflicts with the existence and ubiquity of neurobiological functions that are evolutionary novel, such as structures underlying reading ability. This conflict has suggested to some that, while the selected effects theory may be relevant to some areas of evolutionary biology, its relevance to neuroscience is (...) marginal. This line of reasoning, however, neglects the fact that synapses, entire neurons, and potentially groups of neurons can undergo a type of selection analogous to natural selection operating over an evolutionary time scale. In the following, I argue that neural selection should be construed, by the selected effect theorist, as a distinct type of function-bestowing process in addition to natural selection. After explicating a generalized selected effects theory of function and distinguishing it from similar attempts to extend the selected effects theory, I do four things. First, I show how it allows one to identify neural selection as a distinct function-bestowing process, in contrast to other forms of neural structure formation such as neural construction. Second, I defend the view from one major criticism, and in so doing I clarify the content of the view. Third, I examine drug addiction to show the potential relevance of neural selection to neuroscientific and psychological research. Finally, I endorse a modest pluralism of function concepts within biology. (shrink)

The functional approach to scientific progress has been mainly developed by Kuhn, Lakatos, Popper, Laudan, and more recently by Shan. The basic idea is that science progresses if key functions of science are fulfilled in a better way. This chapter defends the function approach. It begins with an overview of the two old versions of the functional approach by examining the work of Kuhn, Laudan, Popper, and Lakatos. It then argues for Shan’s new functional approach, in which scientific progress is (...) defined as an increase of usefulness of exemplary practices. (shrink)

This paper argues that proper functions are proximal functions. In other words, it rejects the notion that there are distal biological functions – strictly speaking, distal functions are not functions at all, but simply beneficial effects normally associated with a trait performing its function. Once we rule out distal functions, two further positions become available: dysfunctions are simply failures of proper function, and pathological conditions are dysfunctions. Although elegant and seemingly intuitive, this simple view has had surprisingly little uptake in (...) the literature. Indeed, our position departs from that of almost every theorist who has engaged with the issue at any depth. We start by presenting three arguments for the position that proper functions are proximal: one from the specificity of functions, one from their relation to intervention, and one from their relation to pathology. We then consider two case studies evidencing the trouble that accepting distal functions causes for philosophical reflection on the nature of pathological conditions. Finally, we anticipate and respond to three objections: that there can be failure of function without dysfunction; that our account is unacceptably revisionary in respect of normal function-talk; and that our thesis over-generalises from a narrow set of cases. (shrink)

This paper proposes a functional approach to characterize epistemic and nonepistemic values. The paper argues that epistemic values are functionally homogeneous since they act as criteria to evaluate the epistemic virtues a hypothesis ought to possess, and they validate scientific knowledge claims objectively. Conversely, non-epistemic values are functionally heterogeneous since they may promote multiple and sometimes conflicting aims in different research contexts. An incentive of espousing the functional approach is that it helps us understand how values can operate in appropriate (...) and inappropriate ways in scientific research and inappropriate influences can eventually be prevented. The idea is to argue that since non-epistemic values are functionally heterogeneous, they cannot provide objective reasons for the acceptance of a hypothesis. However, their involvement is necessary in certain research contexts and the problem is the involvement of these need not be always legitimate. By analyzing a case from chemical research, I demonstrate that how non-epistemic values might influence scientific research and, then, I go on to demonstrate that how a proper understanding of the functions of different kinds of values might promote the attainment of multiple goals of a particular research in a legitimate and socially relevant way. (shrink)

But what are functions? Here, 15 leading scholars of philosophy of psychology and philosophy of biology present new essays on functions.

This paper argues that a minimal notion of function and a notion of normal-proper function are used in explaining how bodies and brains operate. Neither is Cummins’ notion, as originally defined, and yet his is often taken to be the clearly relevant notion for such an explanatory context. This paper also explains how adverting to normal-proper functions, even if these are selected functions, can play a significant scientific role in the operational explanations of complex systems that physiologists and neurophysiologists provide, (...) despite a lack of relevant causal efficacy on the part of such functions. (shrink)

Different cognitive functions recruit a number of different, often overlapping, areas of the brain. Theories in cognitive and computational neuroscience are beginning to take this kind of functional integration into account. The contributions to this special issue consider what functional integration tells us about various aspects of the mind such as perception, language, volition, agency, and reward. Here, I consider how and why functional integration may matter for the mind; I discuss a general theoretical framework, based on generative models, that (...) may unify many of the debates surrounding functional integration and the mind; and I briefly introduce each of the contributions. (shrink)

A proper function of an entity is a beneficial effect that helps explain the persistence of the entity. Proper functions thereby arise through feedback mechanisms with beneficial effects as inputs and persistence as outputs. We continue to make assertions because they benefit speakers by benefiting speakers. Hearers benefit from true information. Speakers benefit by influencing hearer belief. If hearers do not benefit, they will not form beliefs in response to assertions. Speakers can then only maintain influence by providing true information, (...) often enough. The function of assertion is then inducing true hearer belief. When interests conflict, however, some mechanism must ensure that speakers provide true information often enough, instead of deceiving, or providing information regardless of quality. In humans, a core mechanism stabilizing true assertion involves social norms for truth telling. We tell the truth partly because we prescribe and enforce telling the truth. (shrink)

Functional language is ubiquitous in ecology, mainly in the researches about biodiversity and ecosystem function. However, it has not been adequately investigated by ecologists or philosophers of ecology. In the contemporary philosophy of ecology we can recognize a kind of implicit consensus about this issue: while the etiological approaches cannot offer a good concept of function in ecology, Cummins’ systemic approach can. Here we propose to go beyond this implicit consensus, because we think these approaches are not adequate for ecology. (...) We argue that a sound epistemological framework to function in ecology is to be found in organizational approaches. In this line, we define function in ecology as a precise effect of a given constraint on the ecosystem flow of matter and energy performed by a given item of biodiversity, within a closure of constraints. We elaborate on this definition by developing a case study of a bromeliad ecosystem. (shrink)

The present study examines the comorbidity between specific learning disorders and attention deficit and hyperactivity disorder by comparing the neuropsychological profiles of children with and without this comorbidity. Ninety-seven schoolchildren from 8 to 14 years old were tested: a clinical sample of 49 children with ADHD, SLD or SLD in comorbidity with ADHD, and 48 typically-developing children matched for age and intelligence. Participants were administered tasks and questionnaires to confirm their initial diagnosis, and a battery of executive function tasks testing (...) inhibition, shifting, and verbal and visuospatial updating. Using one-way ANOVAs, our results showed that all children in the clinical samples exhibited impairments on EF measures when compared with TD children. A more specific pattern only emerged for the updating tasks. Only children with SLD had significant impairment in verbal updating, whereas children with ADHD, and those with SLD in comorbidity with ADHD, had the worst performance in visuospatial updating. The clinical and educational implications of these findings are discussed. (shrink)

This article presents a distinct sense of ‘mechanism’, which I call the functional sense of mechanism. According to this sense, mechanisms serve functions, and this fact places substantive restrictions on the kinds of system activities ‘for which’ there can be a mechanism. On this view, there are no mechanisms for pathology; pathologies result from disrupting mechanisms for functions. Second, on this sense, natural selection is probably not a mechanism for evolution because it does not serve a function. After distinguishing this (...) sense fromsimilar explications of ‘mechanism’, I argue that it is ubiquitous in biology and has valuable epistemic benefits. (shrink)

This study examined the relationship between individual differences in executive functions (EF; assessed by measures of working memory, Stroop, trail making, and verbal fluency) and ability to down-regulate and up-regulate responses to emotionally evocative film clips. To ensure a wide range of EF, 48 participants with diverse neurodegenerative disorders and 21 older neurologically normal ageing participants were included. Participants were exposed to three different movie clips that were designed to elicit a mix of disgust and amusement. While watching the films (...) they were either instructed to watch, down-regulate, and up-regulate their visible emotional responses. Heart rate and facial behaviours were monitored throughout. Emotion regulatory ability was operationalised as changes in heart rate and facial behaviour in the down- and up-regulation conditions, controlling for responses in the watch condition. Results indicated that higher verbal fluency scores were related to greater ability to regulate emotion in both the down-regulation and up-regulation conditions. This finding remained significant even after controlling for age and general cognitive functioning. No relationships were found between emotion regulation and the other EF measures. We believe these results derive from differences among EF measures, with verbal-fluency performance best capturing the complex sequence of controlled planning, activation, and monitoring required for successful emotion regulation. These findings contribute to our understanding of emotion–cognition interaction, suggesting a link between emotion-regulatory abilities and individual differences in complex executive functions. (shrink)

All sufficiently large functional notations (ideographic or otherwise) are composites of discrete, structured elements (e.g., phonemes, morphemes, numerals). We must consider not only the modality but also the structure of the existing, workable ideographic/semasiographic systems we know (e.g., musical and numerical notation) to establish the cognitive limitations militating against humans memorizing and standardizing domain-general ideographies that would parallel written language.

In this paper we integrate claims and findings concerning the social functions of emotions at the individual, dyadic, group, and cultural levels of analysis. Across levels of analysis theorists assume that emotions solve problems important to social relationships in the context of ongoing interactions. Theorists diverge, however, in their assumptions about the origins, defining characteristics, and consequences of emotions, and in their preferred forms of data. We illustrate the differences and compatibilities among these levels of analysis for the specific case (...) of embarrassment. We close by suggesting research strategies that incorporate a social-functional perspective. (shrink)

ObjectivesAbnormal brain function in ASD patients changes dynamically across developmental stages. However, no one has studied the brain function of prepubertal children with ASD. Prepuberty is an important stage for children’s socialization. This study aimed to investigate alterations in local spontaneous brain activity in prepubertal boys with ASD.Materials and MethodsMeasures of the amplitude of low-frequency fluctuations and regional homogeneity acquired from resting-state functional magnetic resonance imaging database, including 34 boys with ASD and 49 typically developing boys aged 7 to 10 (...) years, were used to detect regional brain activity. Pearson correlation analyses were conducted on the relationship between abnormal ALFF and ReHo values and Autism Diagnostic Observation Schedule and Autism Diagnostic Interview-Revised scores.ResultsIn the ASD group, we found decreased ALFF in the left inferior parietal lobule and decreased ReHo in the left lingual gyrus, left superior temporal gyrus, left middle occipital gyrus, and right cuneus. There were negative correlations between ReHo values in the left LG and left STG and the ADOS social affect score and a negative correlation between ReHo values in the left STG and the calibrated severity total ADOS score.ConclusionBrain regions with functional abnormalities, including the left IPL, left LG, left STG, left MOG, and right cuneus may be crucial in the neuropathology of prepubertal boys with ASD. Furthermore, ReHo abnormalities in the left LG and left STG were correlated with sociality. These results will supplement the study of neural mechanisms in ASD at different developmental stages, and be helpful in exploring the neural mechanisms of prepubertal boys with ASD. (shrink)

The etiological approach to ‘proper functions’ in biology can be strengthened by relating it to Robert Cummins' general treatment of function ascription. The proper functions of a biological trait are the functions it is assigned in a Cummins-style functional explanation of the fitness of ancestors. These functions figure in selective explanations of the trait. It is also argued that some recent etiological theories include inaccurate accounts of selective explanation in biology. Finally, a generalization of the notion of selective explanation allows (...) an analysis of the proper functions of human artifacts. (shrink)

We give a reduction of the function field Mordell–Lang conjecture to the function field Manin–Mumford conjecture, for abelian varieties, in all characteristics, via model theory, but avoiding recourse to the dichotomy theorems for (generalized) Zariski geometries. Additional ingredients include the “Theorem of the Kernel”, and a result of Wagner on commutative groups of finite Morley rank without proper infinite definable subgroups. In positive characteristic, where the main interest lies, there is one more crucial ingredient: “quantifier-elimination” for the corresponding [Formula: see (...) text] where [Formula: see text] is a saturated separably closed field. (shrink)

Various prominent theories of pain assume that it is pain’s biological function to inform organisms about damage to their bodies. I argue that this is a mistake. First, there is no biological evidence to support the notion that pain was originally selected for its informative capacities, nor that it currently contributes to the fitness of organisms in this specific capacity. Second, neurological evidence indicates that modulating mechanisms in the nociceptive system systematically prevent pain from serving a primarily informative role. These (...) considerations threaten to undermine standard perceptual and representational accounts of pain. (shrink)

Body representations traverse the whole of the brain. They provide vital sources of information for every facet of an animal’s behavior, and such direct neural connectivity of visceral input throughout the nervous system demonstrates just how strongly cognitive systems are linked to bodily representations. At each level of the neural axis there are visceral appraisal systems that are integral in the organization of action. Cognition is not one side of a divide and viscera the other, with action merely a reflexive (...) outcome. There is no divide between cognition and bodily functions once the brain is involved. Cognitive mechanisms that permeate neural function are a cardinal piece of biological function and adaptation. (shrink)

Justin Garson has recently argued that proper functions are proximal activities of traits selected by phylogenetic or ontogenetic selection processes, and that traits are dysfunctional only if they cannot perform their proper functions for constitutional reasons. We partially agree with Garson, but reject the view that functions are proximal activities, as well as his account of dysfunctions. Instead, we propose our own theory that biological functions are selected dispositions and that a trait is dysfunctional in virtue of not having the (...) dispositions for which it was selected. This account can explain both defects (or dysfunctions in Garson’s sense) and dysfunctions due to environmental factors. Moreover, it offers a neat way to explain the graduality of dysfunction. (shrink)

Our aim in this paper is to provide a referential account of functional anaphora within a Skolem functions framework. We will give an interpretation of indefinite NPs as Skolem terms in order to show that the referential link established between an anaphoric pronoun and its antecedent is a descriptive one. Then we will argue that functional anaphora can be understood as a particular kind of E-type pronouns, in the sense that, for a large corpus, the pronoun can be replaced by (...) a descriptive expression of a first-order language. It will next be shown that the functional framework can be fruitfully applied to other kinds of sentences involving pronominal anaphora,especially in modal contexts. (shrink)

A satisfactory analysis of human deception must rule out cases where it is a mistake or an accident that person B was misled by person A's behavior. Therefore, most scholars think that deceivers must intend to deceive. This article argues that there is a better solution: rather than appealing to the deceiver's intentions, we should appeal to the function of their behavior. After all, animals and plants engage in deception, and most of them are not capable of forming intentions. Accordingly, (...) certain human behavior is deceptive if and only if its function is to mislead. This solves our problem because if the function of A's behavior was to mislead, B's ending up misled was not an accident or a mere mistake even if A did not intend to deceive B. (shrink)

There are many different notions of information in logic, epistemology, psychology, biology and cognitive science, which are employed differently in each discipline, often with little overlap. Since our interest here is in biological processes and organisms, we develop a taxonomy of functional information that extends the standard cue/signal distinction (in animal communication theory). Three general, main claims are advanced here. (1) This new taxonomy can be useful in describing learning and communication. (2) It avoids some problems that the natural/non-natural information (...) distinction faces. (3) Functional information is​ ​produced through exploration and stabilisation processes. (shrink)

On one manuscript page of the Opus postumum Kant twice recurs to a passage from Paradise Lost that, seven years earlier, he had cited to exemplify aesthetic ideas and the concept of succession.1 Now he calls on these same verses to perform an additional function, namely, to represent the a priori idea of a community of reciprocity. For Kant, the “insertion” of this idea serves as an “actus of cognition” that can enable experience of the “subjectively actual”.2In the cited passage (...) from Paradise Lost, Raphael instructs Adam about the “reciprocal … Male and Female Light” of the “two great Sexes” that “animate the World”. On the Opus postumum page, Kant names Milton... (shrink)

This is a short overview of the biological functions debate in philosophy. While it was fairly comprehensive when it was written, my short book ​A Critical Overview of Biological Functions has largely supplanted it as a definitive and up-to-date overview of the debate, both because the book takes into account new developments since then, and because the length of the book allowed me to go into substantially more detail about existing views.

Evidence suggests that research participants often fail to recall much of the information provided during the informed consent process. This study was conducted to determine the proportion of consent information recalled by drug court participants following a structured informed consent procedure and the neuropsychological factors that were related to recall. Eighty-five participants completed a standard informed consent procedure to participate in an ongoing research study, followed by a 17-item consent quiz and a brief neuropsychological battery 2 weeks later. Participants performed (...) within the normal range on most of the neuropsychological measures, although roughly one third showed deficits on measures of executive functioning. Participants failed to recall over 65% of the consent information within 2 weeks of entering the study, and their recall was significantly correlated with verbal IQ, drug problem severity, reading ability, memory, and attention. These factors may be useful in determining whether research participants require enhanced consent procedures. (shrink)

Along with technological progress, vocational education and training (VET) is consistently changing. Workforce disruption has serious consequences for workers and international economies, often requiring adults to transition into different occupations or to upskill to maintain employment. We review recent literature covering VET trends, theoretical considerations for the 21st century, and present an approach to workforce training to help workers not only learn necessary skills but also become adaptable to constant change. We suggest a functional contextualist approach to mastery learning achieves (...) this aim. Specifically, we offer suggestions for pedagogy that not only develop skills but also encourage higher order thinking. Within a novice to expert continuum, we suggest deliberate practice, mental simulation, and reflective meaning making as methods to achieve efficiency and transfer—learning outcomes relevant to a changing workforce. This approach recognizes that learning is context bound and should promote broader human capabilities that support both employability and the continuing development of life literacies. (shrink)

Background and PurposeTranscranial direct current stimulation is an emerging non-invasive neuromodulation technique for focal epilepsy. Because epilepsy is a disease affecting the brain network, our study was aimed to evaluate and predict the treatment outcome of cathodal tDCS by analyzing the ctDCS-induced functional network alterations.MethodsEither the active 5-day, −1.0 mA, 20-min ctDCS or sham ctDCS targeting at the most active interictal epileptiform discharge regions was applied to 27 subjects suffering from focal epilepsy. The functional networks before and after ctDCS were (...) compared employing graph theoretical analysis based on the functional magnetic resonance imaging data. A support vector machine prediction model was built to predict the treatment outcome of ctDCS using the graph theoretical measures as markers.ResultsOur results revealed that the mean clustering coefficient and the global efficiency decreased significantly, as well as the characteristic path length and the mean shortest path length at the stimulation sites in the fMRI functional networks increased significantly after ctDCS only for the patients with response to the active ctDCS. Our prediction model achieved the mean prediction accuracy of 68.3% after the nested cross validation. The mean area under the receiver operating curve was 0.75, which showed good prediction performance.ConclusionThe study demonstrated that the response to ctDCS was related to the topological alterations in the functional networks of epilepsy patients detected by fMRI. The graph theoretical measures were promising for clinical prediction of ctDCS treatment outcome. (shrink)

1. IntroductionIn What Biological Functions Are and Why They Matter, Justin Garson offers a novel theory of biological functions, the generalized selected effects (GSE) theory.1 He presents the theory in a clear and comprehensive way, defends it against various objections and applies it to different areas of philosophy, including the philosophy of psychiatry, the debate about mechanisms and the debate about teleosemantic theories of mental content.2Like other proponents of the aetiological approach to functions, Garson maintains that a trait’s biological functions (...) are grounded in its selectional history. However, his GSE theory differs from standard versions of the aetiological approach – so-called selected effects (SE) theories – in a crucial respect: while SE theories assume that all biological functions must ultimately be grounded in phylogenetic processes of natural selection or other (closely analogous) processes of differential reproduction (Millikan 1984: 15–82, Neander 1991, Godfrey-Smith 1994), the GSE theory allows that functions may also be grounded in processes of differential retention (see §2 for details). Garson forcefully argues that this broader account is theoretically well-motivated and has significant advantages over standard SE accounts when it comes to accommodating certain important classes of ontogenetically determined functions. (shrink)

" The Derrida Archive is divided into Critical and Supporting Receptions. This is an analysis of the Functions that the monograph finds working.

Radioactivity accompanied by ionizing radiation has always existed on the Earth, as well as in space, and so in every living tissue there are traces of radioactivity. With the discovery of the said radiation and identifying its effects on the human body, the fear of this phenomenon appeared. At high doses radiation causes serious tissue damages, while at small doses it can cause cancer and induce genetic defects. The best antidote for fear is knowledge. It is important to know the (...) margins safety of radiation for human life. As a result, the topic of radioactive contamination of the environment has now become one of the most significant. In recent years the radon problem is a subject of a wide debate of geologists, geophysicists, ecologists, physicians, specialists in radiometry, and, of course, philosophers and sociologists, since the need for assessing the potential radon danger concerns human lives, human functions in society, and human future. (shrink)

When teachers, students or professors attend a Philosophy for Children training conference, they are expected, amongst other things to "lead" some sessions,. The activity of leading sessions is modelled by the workshop director or by coaches, and participants are usually advised as to how to prepare for their session "on". Sometimes participants become confused as to what exactly they are required to do. And sometimes this confusion is general. It seems to me that part of the confusion results from the (...) fact that the sessions at the conferences serve at least four different functions. And sometimes the requirements of the different functions actually conflict with each other. (shrink)

We sketch a novel and improved version of Boorse’s biostatistical theory of functions. Roughly, our theory maintains that (i) functions are non-negligible contributions to survival or inclusive fitness (when a trait contributes to survival or inclusive fitness); (ii) situations appropriate for the performance of a function are typical situations in which a trait contributes to survival or inclusive fitness; (iii) appropriate rates of functioning are rates that make adequate contributions to survival or inclusive fitness (in situations appropriate for the (...) performance of that function); and (iv) dysfunction is the inability to perform a function at an appropriate rate in appropriate situations. Based on our theory, we sketch solutions to three problems that have afflicted Boorse’s theory of function, namely, Kingma’s ([2010]) problem of the situation-specificity of functions, the problem of multi-functional traits, and the problem of how to distinguish between appropriate and inappropriate rates of functioning. (shrink)