On May 24, 1995, the American Medical Association Council on Ethical and Judicial Affairs issued a rather controversial opinion that it is ethically permissible to use anencephalic infants as living organ donors. Approximately 1,000 to 2,000 infants are born each year in the United States with anencephaly, a congenital birth defect whereby the infant has no forebrain and cerebrum. Without higher brain functions, the infants can never experience consciousness, thoughts, emotions, or pain. Fewer than half survive more than a day, (...) and more than 90 percent die within one week. However, by the time brain death occurs in anencephalic infants, their organs are no longer suitable for donor purposes because they have deteriorated beyond use.In 1988, the AMA Council declared that it is ethical to use the infants as organ donors only after they have died. Now the Council has revised that opinion, and it proposes to allow removal of organs before death, as long as the parents consent and two doctors concur in the diagnosis of anencephaly. (shrink)

Company–community agreements are widely considered to be a practical mechanism for recognising the rights, needs and priorities of peoples impacted by mining, for managing impacts and ensuring that mining-derived benefits are shared. The use and application of company–community agreements is increasing globally. Notwithstanding the utility of these agreements, the gender dimensions of agreement processes in mining have rarely been studied. Prior research on women and mining demonstrates that women are often more adversely impacted by mining than men, and face greater (...) challenges in accessing development opportunities that mining can bring. Nonetheless, there is currently little guidance for companies, government or communities in bringing a gender perspective to the fore in mining and agreement processes. It is undisputed in human development literature that investment in women and sensitivity to gender delivers long-term health, education and local development outcomes. In mining and development, a number of key factors remain unexplored. These include: women’s participation in agreement processes, the gendered distribution of agreement benefits, and the extent to which impacts and benefits influence women’s development and economic inclusion. This paper presents the results of the first phase of an applied research project undertaken by the Centre for Social Responsibility in Mining at The University of Queensland and funded by the Minerals Council of Australia and the Department of Foreign Affairs and Trade. The project sought to connect with experienced practitioners who had been directly involved in mining and agreement processes to document and analyse grounded perspectives on gender dynamics and agreements, and connect those experiences with the broader literature. Findings from this study have implications for the role of mining companies and governments in promoting gender equality and empowerment as part of their commitments to sustainable development. They also have implications for community groups and their representatives in terms of how they might engage in agreement processes to maximise women’s participation and influence. In many social contexts, a key challenge will be navigating the territory of cultural norms and gender equality, particularly in cultures where women’s influence in the public sphere is not strong. The authors argue that without consideration of a gender perspective, including gender’s intersection with other factors such as class, race, poverty level, ethnic group and age, mining agreements will not be inclusive, may exacerbate gender inequalities, and fail to contribute to long-term sustainable development. (shrink)

Many structures in nature are invariant under the transformation pair, (p,r)→(b r,−p/b), where b is some scale factor. Born’s reciprocity hypothesis affirms that this invariance extends to the entire Hamiltonian and equations of motion. We investigate this idea for atomic physics and galactic motion, where one is basically dealing with a 1/r potential and the observations are very accurate, so as to determine the scale b≡mΩ. We find that an Ω∼1.5×10−15 s−1 has essentially no effect on atomic physics but might (...) possibly offer an explanation for galactic rotation, without invoking dark matter. (shrink)

Recent books by Paul Johnston, D. Z. Phillips, Philip Shields, and B. R. Tilghman all depict Wittgenstein as centrally concerned with ethics, but they range from representing his main works as expressing and advocating a particular religious-ethical outlook to arguing that his work has no ethical content but aims primarily to clarify such logical distinctions as that between ethical and empirical judgments. All four books raise the question about the moral philosopher's proper role, and each suggests a rather different answer. (...) Via the discussion of these books, I argue that Wittgenstein's stress on diversity in the ways of human life, his notion of conceptual grammar, the idea of a perspicuous representation, his lifelong involvement with art and his suggestions about its connection with morality, and his preoccupation with aspect-seeing-all suggest new possibilities of rehabilitating the historically recurrent idea that the philosopher may be a moral sage. (shrink)

The idea that bureaucracy is a «rational» and «depoliticized» instrument in the conduct of public affairs, has recently come under severe criticism. Assuming the inevitable trend towards «politicization», modern bureaucracies can possibly be classified info four different categories, i.e. : «De-politicized», «Semi-politicized», «Committed» and «Fully-politicized». Such a classification is based on the operationalization of certain indices on four different dimensions viz. a) Degree of Bureaucracy's Influence in Decision-making; b) Degree of its Involvement in Political Activities; c) Degree of Political Interference (...) in its Work and d) its Image in the Public. The extent of «politicization» of any bureaucratic system and its actual deviation from the defined categories will, however, depend upon the available pattern of the characteristic indices in that particular society. Notwithstanding certain difficulties in the operationalization of such indices, the model should be helpful in providing a framework for a comparative analysis and measurement of «politicization» of bureaucracies in different political systems. (shrink)

Background: Since the passage of the Patient Self-Determination Act, numerous policy mandates and institutional measures have been implemented. It is unknown to what extent those measures have affected end-of-life care, particularly with regard to the do-not-resuscitate order.Methods: Retrospective cohort study to assess associations of the frequency and timing of DNR orders with advance directive status, patient demographics, physician’s specialty and extent of documentation of discussion on end-of-life care.Results: DNR orders were more frequent for patients on a medical service than on (...) a surgical service and were made earlier in the hospital stay for medicine than for surgical patients . 22.18% of all patients had some form of an advance directive in their chart, yet this variable had no impact on the frequency or timing of DNR ordering. Documentation of DNR discussion was significantly associated with the frequency of DNR orders and the time from DNR to death .Conclusions: The physician’s specialty continues to have a significant impact on the frequency and timing of DNR orders, while advance directive status still has no measurable impact. Additionally, documentation of end-of-life discussions is significantly associated with varying DNR ordering rates and timing. (shrink)

lecting statistics about missing bindings and macros, and other errors. This guides debugging and development efforts, leading to iterative improvements in both the tools and the quality of the converted corpus. The build system thus serves as both a production conversion engine and software test harness. We have now processed the complete arχiv collection through 2006 consisting of more than 400,000 documents (a complete run is a processor-yearsize undertaking), continuously improving our success rate. We are now able to convert more (...) than 90% of these documents to XHTML+MathML. We consider over 60% to be successes, converted with no or minor warnings. While the remaining 30% can also be converted, their quality is doubtful, due to unsupported macros or conversion errors. (shrink)

Summary A study of the metallurgy and manufacturing techniques of a group of eight astrolabes (seven from Lahore, one attributed to India) using non-destructive methods has produced the earliest evidence for systematic use of high-zinc (α?+??) brass. To produce this alloy, the brass industry supplying the Lahore instrument makers must have co-melted metallic copper and zinc. This brass-making technology was previously believed to have been developed on an industrial scale in the nineteenth century in Europe. This work hypothesizes that this (...) technology was used in Lahore on an industrial scale as early as ad 1601. In addition, this work hypothesizes that the α?+?? brass alloy was used specifically for its ease in manufacturing the thin sheet brass required for astrolabe-component manufacture. (shrink)

Summary A study of the metallurgy and manufacturing techniques of a group of eight astrolabes using non-destructive methods has produced the earliest evidence for systematic use of high-zinc brass. To produce this alloy, the brass industry supplying the Lahore instrument makers must have co-melted metallic copper and zinc. This brass-making technology was previously believed to have been developed on an industrial scale in the nineteenth century in Europe. This work hypothesizes that this technology was used in Lahore on an industrial (...) scale as early as ad 1601. In addition, this work hypothesizes that the α + β brass alloy was used specifically for its ease in manufacturing the thin sheet brass required for astrolabe-component manufacture. (shrink)

The purpose of this study was to empirically investigate the role of pluralistic ignorance in perceptions of unethical behavior. Buckley, Harvey, and Beu (2000) suggested that pluralistic ignorance plays a role such that individuals mistakenly believe that others are more unethical than they actually are. In two studies, we confirmed that pluralistic ignorance influences perceptions of ethics in a manner consistent with what Buckley et al. suggested. The implications of pluralistic ignorance in perceptions of ethics are discussed with suggestions for (...) how pluralistic ignorance might be reduced and how research in this area may be extended. (shrink)

This paper examines some ethical issues arising from whole-genome association studies for multigenic diseases, focusing on the case of autism. Events occurring following the announcement of a genetic test for autism in France (2005–2009) are described to exemplify the ethical controversies that can arise when genetic testing for autism is applied prematurely and inappropriately promoted by biotech companies. The authors argue that genetic tests assessing one or a few genes involved in highly multigenic disorders can only be useful if: (1) (...) the genetic linkage found in the scientific study must be statistically convincing, reproducible and also applicable to the population to which the individual considered belongs (scientific validity); (2) the relative risk conferred by the ‘high-risk’ allele should be high enough to be significant to the patient (significant impact); (3) use of the test should lead to some improvement of outcome for the patient, resulting from adapted treatment if available, or at least from adjustment of lifestyle (or life goals) prompted by the new knowledge generated (clinical utility). Decisions concerning genetic testing for autism involve scientific judgement, value judgement and good knowledge of a constantly evolving therapeutic environment. The implementation of genetic tests for highly multigenic diseases thus requires strong mechanisms to ensure that they are used in a fashion that can benefit patients, and these mechanisms must be able to cope with rapid progress in scientific knowledge and therapeutic intervention. (shrink)

A selection of articles originally written in English for the New York Tribune and here edited with an eye to proving the tantalizing thesis "that for Karl Marx antagonism between capital and labor took second place to the eternal duel between East and West, in which his sympathies... lay unequivocally with the West." Although these articles, dealing mainly with the Crimean War, merit greater attention than they have thus far received, this edition is misleading in two critical aspects: 1) Many (...) of the articles signed by Marx in the New York Tribune, especially those dealing with military affairs, were actually written by Engels. The crucial document for distinguishing them, a notebook kept by Marx's wife, is acknowledged to be in Moscow, but the editor makes no mention of this. 2) The editor also gives no hint of Marx's many other statements on Russia, especially in his preface to the second edition of Capital and in his correspondence with Vera Zasulich.--K. R. D. (shrink)

In his article ‘A Cavalry Unit in the Army of Antigonus Monophthalmus: Asthippoi’, N. G. L. Hammond argues that the reading of the manuscript R at Diodorus 19. 29. 2 should be retained and that we should read ⋯π⋯ π⋯σι δ⋯ το⋯ς τε ⋯σθ⋯ππους ⋯νομαζομ⋯νους κα⋯ τοὺς ⋯κ τ⋯ν ἄνω κατοικο⋯ντων ⋯κτακοσιο⋯ς. The readings of F and its copy X, ⋯νθ⋯ππους, and the commonly accepted conjecture of Wesseling ⋯μɸ⋯ππους, should both be abandoned. Hammond's arguments for retaining this reading are that (...) between the variant readings of R and F, R ‘is the more often correct’ ; ⋯σθ⋯ππους, the reading of R, is preferable to F's ⋯νθ⋯ππους on the principle of ‘lectio difficilior’; the ‘difficulty’ of his lectio difficilior is made less by the arguments presented by A. B. Bosworth, 245 ff.), for the restoration at several places in the text of Arrian's Anabasis the word ⋯σθ⋯ταιροι, in place of the editorial emendation of πεζ⋯ταιροι. ‘For just as asthetairoi meant an élite group of Macedonian infantrymen,’ says Hammond, ‘so asthippoi should mean an élite group of Macedonian cavalrymen.’ He then proceeds to examine the passage and its context in an attempt to find confirmation of this proposition and comes to the conclusion that Diodorus' text says that there were 800 cavalrymen, broken into two groups, the asthippoi and ‘the men from the up-country settlers’; these, though having different names, had a close relationship to each other, as is shown by their being brigaded together. Following his derivation of asthetairoi as meaning ‘townsmen-companions’, i.e. companions recruited from the towns of Upper Macedonia, he argues that asthippoi were cavalry recruited from the towns of Upper Macedonia and that τοὺς ⋯κ τ⋯ν ἄνω κατοικο⋯ντων means ‘the sons of settlers in up-country Macedonia’. These 800, says Hammond, were both among Antigonus' best troops and ‘were Macedonians from Europe’. We thus appear, on Hammond's interpretation, to have here a group of 800 Macedonian élite cavalrymen, all of whom were recruited in Upper Macedonia's townships, but of whom some were chosen to be the cavalry-equivalent of the élite ‘townsmen-companions’ by their title of ‘townsmen-cavalry’, whilst the others, similarly recruited – but perhaps of a younger generation? – had no particular distinguishing title beyond ‘sons of settlers in up-country Macedonia’.Now, while it would be exciting to be able to add another one, possibly two Macedonian cavalry units to the Macedonian army of Philip, Alexander and the Successors, there are several aspects of Hammond's arguments that, it seems to me, are less than convincing. Thus, whilst it seems beyond reasonable doubt that ⋯σθ⋯ταιροι should be retained in the text of Arrian, appearing, as it does, six times, this is not an argument that ⋯σθ⋯ππους should be read in Diodorus' text. Both it and F's reading of ⋯νθ⋯ππους are hapax legomena and it is possible that both readings are wrong. But even if we retain ⋯σθ⋯ππους as the correct reading, Hammond's explanation of its meaning is open to objection on several counts. (shrink)

The question of whether or not children may be used as subjects in non-therapeutic research projects has generated a great deal of debate and received answers varying from 'no, never' to 'yes, if societal interests are served'. It has been claimed that a Kantian, deontological ethics would necessarily rule out such research, since valid consent would be impossible. The present paper gives a deontological argument for allowing children to be subjects in certain types of research.

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Many social scientists and philosophers have counted themselves moral relativists in some sense or other. We cannot deal with all the various views which are properly called forms of “moral relativism”; so I propose to explain a form of moral relativism which seems to me an interesting, and somewhat plausible theory. This theory comprises the following three affirmations: The basic moral principles of different individuals or groups sometimes are, or can be, in some important sense conflicting. When there is such (...) fundamental conflict of basic principles or standards, there is either always, or at least sometimes, no way to show that one view is better justified even in the presence of ideally complete factual information; in that sense the principles are equally justified or “valid.” But there is a sense in which a particular moral belief may be mistaken or unjustified, if it is a misapplication of the basic principles of the individual or group, e.g., if the basic principles plus statements of known or knowable facts entail a moral proposition incompatible with it. As stated, moral relativism could be true even though in fact, accidentally, all individuals agree in their basic moral principles. (shrink)

James Bohman’s account of what might be involved in thinking about ‘democracy across borders,’ and specifically of what might be involved in thinking about a potential shift from dêmos to dêmoi, compels both affirmation and resistance. His account is both elegant and sharply focussed: positive attributes that nevertheless affirm a very particular understanding of elegance, and a precise focus that manages to evade many considerations that might be considered important by people seeking to think about democracies and their futures in (...) many different situations. (Published: 5 February 2010) Citation: Ethics & Global Politics, Vol. 3, No. 1, 2010, pp. 21-36. DOI: 10.3402/egp.v3i1.4851. (shrink)

This paper first appeared in Modern Theology, Vol. 6, No. 3, July 1989. Copyright (c) Basil Blackwell Publisher Ltd., Oxford. Reprinted by permission.

The apolipoprotein E gene plays an important role in the pathogenesis of Alzheimer's disease , and amyloid plaque comprised mostly of the amyloid-beta peptide ) is one of the major hallmarks of AD. However, the relationship between these two important molecules is poorly understood. We examined how A treatment affects APOE expression in cultured cells and tested the role of the transcription factor NF-B in APOE gene regulation. To delineate NF-B's role, we have characterized a 1098 nucleotide segment containing the (...) 5'-flanking region of the human APOE gene . Sequence analysis of this region suggests the presence of two potential NF-B elements. To demonstrate promoter activity, the region was cloned upstream of a promoterless luciferase gene. This segment was able to drive expression of luciferase in transient transfections of human fetal glial cells. Promoter activity was stimulated twofold by A treatment. Pretreatment with double-stranded DNA decoy oligonucleotides against NF-B reduced A stimulation. Deletion and mutagenetic analyses demonstrated that the distal NF-B element was functional and showed a strong DNA-protein complex band in gel shift analysis, similar to that from control NF-B consensus element. An anti-inflammatory and anti-NF-B drug, sodium salicylate, significantly blocked A-induced APOE promoter function. Our data provide evidence that upregulation of APOE by A in astroglial cells is mediated by an NF-B-element present in the 5'-flanking region of the APOE gene. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain (...) in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

The modern theoretical physicist is a strange creature. Perhaps in every age the theoretical physicist has seemed so to his contemporaries who took the trouble to observe and think about him. There seems, for example, something almost too magical in the uncanny way in which he pulls a brand new atomic particle out of a theory, a way that reminds us of a rabbit being produced out of a hat. This is usually done in an off-hand manner with a considerable (...) amount of patter of a highly abstract symbolic character but with a few words inserted in the right places for the benefit of the experimental physicist and a final prediction that if the experimenter does thus and so in the laboratory he will find a certain result. No wonder the observer marvels when the answer comes out right. But as he thinks further he is inclined to wonder whether it is necessary or desirable for the details of the process which led to the result to be so unintelligible. For unintelligible they seem to be to a great many people who are directly concerned with their understanding, to the people who for years have been laboring under the belief that they are engaged in the task of finding out how Nature works. What is this curious process whose whole task, according to one distinguished exponent of it, is merely to predict experimental results, and what is its future likely to be? These are the questions we are setting for ourselves in the present discussion. It is unlikely that the answers given here will satisfy everybody, but it is reasonably certain that nobody who aspires to an interest in science can fail to attach some meaning to them whether or not he agrees. (shrink)

The main current application of placebo is in clinical research. The term placebo effect refers to diverse non-specific, desired or non-desired effects of substances or procedures and interactions between patient and therapist. Unpredictability of the placebo effect necessitates placebo-controlled designs for most trials. Therapeutic and diagnostic use of placebo is ethically acceptable only in few well-defined cases. While "therapeutic" application of placebo almost invariably implies deception, this is not the case for its use in research. Conflicts may exist between the (...) therapist's Hippocratic and scientific obligations. The authors provide examples in neuropsychiatry, illustrating that objective scientific data and well-considered guidelines may solve the ethical dilemma. Placebo control might even be considered an ethical obligation but some provisos should be kept in mind: (a) no adequate therapy for the disease should exist and/or (presumed) active therapy should have serious side-effects; (b) placebo treatment should not last too long; (c) placebo treatment should not inflict unacceptable risks, and (d) the experimental subject should be adequately informed and informed consent given. (shrink)

Rome and Carthage had established peaceful diplomatic relations before 300 b.c. — as early as the close of the sixth century according to Polybius, whose dating there no longer seems good cause to doubt. A second treaty was struck probably in 348. Both dealt essentially with traders' and travellers' obligations and entitlements, so any military or political terms sprang from that context. In both, the Carthaginians agreed to hand over any independent town they captured in Latium. In the first treaty (...) they were not to establish a fort in Latium either; in the second, the Romans were not to found a city in Carthaginian Africa, Spain or Sardinia. But independent military considerations are the stuff of a third treaty concluded during Rome's war with Pyrrhus. Rome and Carthage now pledged each other military aid in certain circumstances, as we shall see. And ‘geopolitical’ concerns of a very broad kind imbued a treaty which was reported by the third-century historian Philinus of Agrigentum. By this, he stated, ‘the Romans must keep out of the whole of Sicily, the Carthaginians out of Italy’ . This is Polybius' citation of Philinus' allegation; Polybius himself then roundly rejects the very existence of such a pact and declares himself at a loss to understand how his predecessor could record it, but modern scholarship is no longer all that ready to accept his view. A strong majority of historians prefer to follow the Agrigentine, and many see 306 b.c. as the likely year for the agreement because Livy records a ‘renewal’ then of a foedus with Carthage. (shrink)

Classification of the boys in 48 families of three or more brothers according to their Moray House Test (VIQ) scores awarded at age 11±1[fraction one-half] years in 1947–75 confirms the postulated existence of a total of nine male phenotypes for this X-linked trait in the score range <70 to 140 points. The phenotypic means lie close to the sequence 69(8)133. Recombination is shown to occur. An additive effect of three alleles at each of two X-chromosome loci is the most likely (...) simple scheme. An iterative approach matching the observed mixtures of proposed genotypes in the families with probabilities for variable levels of homozygosity, non-crossover/crossover heterozygosity, and maternal meiotic recombination yields a best goodness of fit where this last is 20%. (shrink)

Scientists, Engineers, Technocrats, Academicians, and Researchers have a vital role to play in the process of emergence of new theories, models, systems, and technologies. They also have a responsibility to harness these for common good and strive to prevent their possible ill effects in the era of rapid growth in technologies. ICM2ST-10 will play a significant role in generating awareness about the potential and the limitations of new technologies, concepts, theories, and trends. The chief objective of ICM2ST-10 is to bring (...) together experts from industries, academia, R&D institutions and other user communities on a common platform to discuss and share their expertise and experiences. (shrink)

The use of virtual fencing in pasture-grazed farm systems is currently close to commercial reality but there are no studies applying the principles of responsible research and innovation, such as foresighting, to this technology. This paper reports results of a study aimed at foresighting potential implications associated with virtual fencing of cattle. A Delphi method was used to survey the opinions of farming practitioners and researchers, using pasture-grazed cattle farming in New Zealand as a case study. The key benefits were (...) identified as environmental protection, improved feed allocation, access to previously unavailable grazing areas, labour savings and individual animal management. The five most important potential barriers identified were device reliability, farmer perception of a value proposition, ethical issues related to community perception of negative animal welfare, lack of feed budgeting skills of farmers, and excessive training time. We suggest that more knowledge is needed on ethical issues associated with VF, including understanding public opinions of such technology developments. We suggest that development and use of VF has been focussed primarily on technical features and user benefits and needs to include consideration of wider socio-ethical principles to ensure responsible innovation processes. The findings from this study will aid focussed research and development to incorporate ethically acceptable development alongside technical factors. (shrink)

The author of this rather lengthy book proposes another way of obtaining a glance at the "heretofore rarely seen unity of the Kantian system." He suggests a common theme present in and often foundational for, many of Kant’s reflections, the notion of "action" ; more generally the notion of the human subject itself as a kind of Handlung. Such a project is certainly a plausible one. Kant’s frequent use of notions like spontaneity, self-legislation, freedom, and others make the prospects for (...) the author’s ambitious attempt at least relatively reasonable. Often, though, instead of a unified interpretation of various texts, we find here just isolated interpretations of Kantian issues, some indeed intimately connected with the theme of action, many tangentially related, a few not at all. The author’s whole approach also causes some difficulties. His style can most charitably be described as idiosyncratic; neologisms and odd contructions abound in every section: "transcendental constellation," "transcendental motion," "world projection," "practical being," "practical apperception," and so on. References to philosophers whose doctrines could, by contrast or similarity, help clarify Kant’s, are almost nonexistent. There is little reference to Leibniz, only a few references to Schelling and Hegel, and no discussion of Fichte’s theory of Tathandlung. Indeed there is no reference to any recent or classic secondary Kant literature. There is also a curious, brief, sweeping dismissal of all "analytic" philosophies of action as all committed to a thoroughly "causal" interpretation of action as observable behavior, predicable of a subject. (shrink)

As the interesting title of this work indicates, its author is concerned less with Kant’s theory of morality, with its account of freedom, the possibility of pure reason being practical, and the deduction of the moral law, than he is with Kant’s Sittenlehre, or the account of the moral law as applied, moral judgment, and the substantive, derived duties of justice and virtue. Accordingly, he concentrates almost exclusively on two texts. The first four chapters are a commentary on and assessment (...) of the three chapters of the Groundwork of the Metaphysic of Morals, and his last two chapters deal with the two main sections of the Metaphysics of Morals. Other important texts of Kant’s moral theory are dealt with, as he says, en passant, and some are not dealt with at all. This approach has the virtue of focusing attention on perhaps the central Kantian moral problem: the nature of the transition from pure moral principles to "morals." It has the defect of being bound in too restrictive a way to the Groundwork as an expression of Kant’s general moral theory. There is no discussion of the synthetic or "regressive" methodology of that work, an approach which Kant realized aided its popular appeal, but greatly limited its theoretical adequacy, nor of the well known revisions Kant made in his moral theory, especially his account of freedom, by 1788. However, the author admits that he did not intend to write a book "directed specifically to Kant scholars." Instead, he tries to keep his discussion of textual interpretation minimal, always tries to present Kant’s arguments in a "contemporary idiom," refers only to English translations, infrequently to the Kant literature, and then only to English language literature. (shrink)

The eight essays assembled under this title were originally presented at the 1965 Great Thinkers Forum sponsored by the Department of Philosophy and Religion at the University of Georgia. These essays are now being published in the conviction that they all make "valuable contributions toward the understanding and resolution of the contemporary challenge to theology and religion." The challenge in question is the one that comes from neopositivism and linguistic analysis. By the time the reader comes to the end of (...) his own effort he finds himself wondering in what sense the 1965 papers are to count as valuable contributions. No doubt they are valuable in the sense that it is worthwhile watching a single-minded philosopher pouring his soul out in an attempt at showing how the "disguised nonsense" of religious language is "patent nonsense," or how the "putatively factual assertions" of religious language are "bogus, pseudo-factual statements, devoid of the kind of intelligibility that believers rightly demand of them." Along the way one may collect pearls of rare beauty, such as the statement that "There is no convention in English or logical rule which makes ‘there is no God’ a contradiction," or questions such as "Who has observed him under controlled conditions?" Another contribution of the same general usefulness may well be that the thoughtful reader is being initiated to the exertions of that transformational hermeneutics by which pseudo-assertive religious statements are being rescued from wholesale meaninglessness, and accorded the innocuous meaningfulness of emotive or convictional language, or of disguised moral discourse. Professor Frank H. Harrison III makes an interesting attempt at injecting into the landscape, linguistically and epistemologically so bleak, what he calls "knowledge by acquaintance," which is in his vocabulary the equivalent of what mysticism calls amor Dei, and Antoine de Saint-Exupéry describes as a seeing with the heart. The discussion of myth by Professor Robert H. Ayers ignores what happens to be the heart of the matter in mythic thinking, namely the absence of the distinction between object and subject, but does provide a good introduction to the "profusion of confusion" that flourishes around myth, "one of the most traveled hobos in our times.". (shrink)

At various times in his "Pre-critical" and "Critical" periods, Kant presented an argument about the nature of space that has come to be called the "Incongruous Counterparts" argument. First presented in his 1768 essay, Concerning the Ultimate Foundation for the Differentiation of Regions in Space, the argument holds that two objects, such as two human hands, might be exact counterparts, that is, identical in "size and proportion and... the situation of the parts relative to each other," and yet might be (...) still "incongruent," that there is no continuous rigid motion which brings them into coincidence in space; or, that they are, though counterparts, incongruently left and right hands. This argument appears in 1768, in the Dissertation of 1770, the Prolegomena of 1783 and the Metaphysical Foundations of Natural Science in 1786. Unfortunately, while the details of the argument are virtually the same, the conclusions are not. Kant seems to have claimed that the argument shows: that a Leibnizean, relational theory of space was wrong; that a theory of absolute space was correct; that space was a pure form of sensibility and that space was transcendentally ideal, i.e., that space was not and could not be a feature of things in themselves. In the secondary literature, commentators who have dealt with this issue have simply noted the odd history of the argument and lamented it. Buroker's ambitious and interesting thesis in this book is not only that Kant's use of the argument is consistent and interconnected, but that the argument can be seen as the "origin" of Kant's idealism. She argues both of these points by arguing, in the great majority of cases, more for a logical than an actual or historical connection among the conclusions Kant drew from the argument; i.e., that she can illuminate the reasoning that led Kant from a rejection of Leibniz's relational view to his radical separation between sensibility and understanding, and then to his view that things in themselves are both unknowable and non-spatial. (shrink)

The main thesis of this excellent little book is that "contrary to widespread misapprehensions, two formally different kinds of utilitarianism, simple and general, and along with the latter one kind of rule-utilitarianism, are extensionally equivalent; that is, analogous principles of the various kinds necessarily yield equivalent judgments in all cases; or, in other words, it makes no difference in theory whether the simple or generalization test is applied to acts or—within limits—whether an appeal is made to rules grounded in utility." (...) The "misapprehension" is dispelled in the particularly valuable third chapter, "Extensional Equivalence," by means of an a priori causal analysis of action situations and an exacting consideration of action descriptions. Furthermore, Lyons argues that other rule-utilitarian theories not extensionally equivalent to the simple utilitarianism of tradition differ from it in the wrong ways. As a result of these two findings the author holds that "any appeal to generalization or to rules consequently fails to escape the force of traditional arguments against utilitarianism." Utilitarian readers who accept Lyons' argument and particularly his interspersed but incisive criticisms of the works of Broad, Harrison, Singer, Harrod, Brandt, and Rawls, are likely to feel that it is best to go back to Mill! But in his final chapter Lyons' analysis of promising and fairness throws doubt on the adequacy of any purely utilitarian moral theory. However this may be, to read Lyons' book is to follow a precise and rigorous intellect, free of current dogmas about value statements, while it threads its way through a maze of conceptual complexities toward substantive philosophic conclusions.—R. B. C. (shrink)

This book discusses the philosophical work of Décio Krause. Non-individuality, as a new metaphysical category, was thought to be strongly supported by quantum mechanics. No one did more to promote this idea than the Brazilian philosopher Décio Krause, whose works on the metaphysics and logic of non-individuality are now widely regarded as part of the consolidated literature on the subject. This volume brings together chapters elaborating on the ideas put forward and defended by Krause, developing them in many different directions, (...) commenting on aspects not completely developed so far, and, more importantly, critically addressing their current formulations and defenses by Krause himself. Given that Krause’s ideas do connect directly and indirectly with a wide array of subjects, such as the philosophy of quantum mechanics, more broadly understood, the philosophy of logic and logical philosophy, non-classical logics, metaphysics, and ontology, this volume contains important material for the research on logic and foundations of science, broadly understood. All the invited contributors have already worked with the ideas developed by Décio (some of them still work with them), being also distinct authors and extremely relevant in their areas of expertise. The volume is aimed at philosophers, including those of physics and quantum mechanics. (shrink)

Nonreflexive quantum mechanics is a formulation of quantum theory based on a non- classical logic termed nonreflexive logic. In these logics, the standard notion of identity, as encapsulated in classical logic and set theories, does not hold in full. The basic aim of this kind of approach to quantum mechanics is to take seriously the claim made by some authors according to whom quantum particles are non-individuals in some sense, and also to take into account the fact that they may (...) be absolutely indistinguishable. The nonreflexive formulation of quantum theory assumes these features of the objects already at the level of the underlying logic, so that no use is required of symmetrization postulates or other mathematical devices that serve to pretend that the objects are indiscernible. Here, we present the ideas of the development of nonreflexive quantum mechanics and discuss some philosophical motivations and consequences of it. (shrink)

This, the third volume in The Pelican History of the Church, offers an extremely perspicacious view of the entire period. While there were nationalistic, economic, and political interests responsible for the Reformation and while there was no one, simple religious motivation, underlying all of these causes was a profound dissatisfaction with the moral and religious tone of late medieval society. However haltingly and destructively the Reformation proceeded, it is evident that the result was a general strengthening of authentic religious life (...) in both Protestant and Catholic countries. And where the state assumed some of the secular functions of the medieval Church this seemed to eventually benefit both Church and State. However, Chadwick does not gloss over grosser aspects of the period: the so-called wars of religion, the endless and destructive polemics between churches, and the ruthless confiscation of ecclesiastical property. If greedy lords helped free the Church from the mammon of iniquity, this was accompanied by cultural and artistic losses with no improvement in the lot of the poor country cleric despite the reduced status of the wealthy bishop or abbot. Chadwick is particularly good in his descriptions of the relationship of the political to the religious. But what is of special interest are the sometimes bewildered and reactionary responses of the little Christian to the dramatic events of the time.—D. J. B. (shrink)

This volume is a revival and updating of the rationalism initiated by the Cartesian cogito. Even the four main divisions of the work give evidence of this: Perception, the Real World, Real Mind, and the Suprarational. The order of treatment is not identical in every respect with that of Descartes, but the four main themes are indubitably Cartesian. While the protagonist is Descartes, the antagonist to whom this volume is consciously addressed is the empiricist and the positivist. Professor Robinson seems (...) intent on convincing the contemporary positivist that science is primarily an affair of reason and secondarily one of experience. He enlists two formidable allies of Descartes to elucidate and solidify his position. One he finds in the same century as Descartes, the redoubtable Leibniz; the other he takes from the twentieth century, Bertrand Russell. The problem of perception is resolved by the joint solution of Leibniz and Russell, a solution which rejects a naive realism in favor of a metarealism. The singular attraction of this volume is the personal dedication and expertise which Professor Robinson brings to this subject. His exploration and defense of his rationalistic premise brings him to examine epistemic issues and paradoxes which have cast long shadows over the history of modern and contemporary philosophy in Western civilization. These are the issues with which the inheritors of the Cartesian cogito have been wrestling: Spinoza, Leibniz, Locke, Berkeley, Hume, and Kant. Another very attractive aspect of this volume is that whereas Professor Robinson’s thesis has its protagonist and antagonist, it does not explicitly address itself to these. They remain more in the background as the audience to whom the book is addressed. They are not called on explicitly to engage in the exposition. In this sense, the book is not presented as a professorial treatise with copious footnotes and an extensive bibliography. It is presented as a personal exposition engaging in the act of philosophizing within the letter and spirit of a rationalistic revival. In spite of this personal and personalized renewal of rationalism on the part of Professor Robinson, it should not be construed that the book is written either for the layman or by a layman. It is a methodical and technical exposition replete with the coinage of new terms befitting the spirit of a philosophy operating within the parameters of a self-enclosed and self-contained scientism. Professor Robinson presents his book as a viable alternative to the monopoly which the empiricist and positivist have exercised within the domain of the philosophy of science.—R.E.D. (shrink)

Two years ago in two articles in a thematic issue of this journal the three of us engaged in a critique of principlism. In a subsequent issue, B. Andrew Lustig defended aspects of principlism we had criticized and argued against our own account of morality. Our reply to Lustig's critique is also in two parts, corresponding with his own. Our first part shows how Lustig's criticisms are seriously misdirected. Our second and philosophically more important part picks up on Lustig's challenge (...) to us to show that our account of morality is more adequate than principlism. In particular we show that recognition of morality as public and systematic enables us to provide a far better description of morality than does principlism. This explains why we adopt the label “Dartmouth Descriptivism.”. (shrink)

Requests by patients or their families for treatment which the patient's physician considers to be "inappropriate" are becoming more frequent than refusals of treatment which the physician considers appropriate. Such requests are often based on the patient's religious beliefs about the attributes of God (sovereignty, omnipotence), the attributes of persons (sanctity of life), or the individual's personal relationship with God (communication, commands, etc). We present four such cases and discuss some of the basic religious tenets of the three Abrahamic faith (...) traditions as they relate to such requests. We suggest that religious reasons for requesting "inappropriate" treatment are "special" and deserve serious consideration. We offer guidance to assist clinicians and clinical ethicists as they attempt to resolve these conflicts, emphasising the importance of understanding the religious beliefs of the patient/surrogate and suggesting the assistance of a religious interpreter. We suggest open discussion with patients and families of both the clinical situation and the theological basis for these requests. We also suggest that clinicians use additional religious doctrines or principles from patients' own traditions to balance the reasons behind the requests. We conclude that most persistent requests for "inappropriate" treatment should be honoured. (shrink)

Journal of the History of Biology provides a fifty-year long record for examining the evolution of the history of biology as a scholarly discipline. In this paper, we present a new dataset and preliminary quantitative analysis of the thematic content of JHB from the perspectives of geography, organisms, and thematic fields. The geographic diversity of authors whose work appears in JHB has increased steadily since 1968, but the geographic coverage of the content of JHB articles remains strongly lopsided toward the (...) United States, United Kingdom, and western Europe and has diversified much less dramatically over time. The taxonomic diversity of organisms discussed in JHB increased steadily between 1968 and the late 1990s but declined in later years, mirroring broader patterns of diversification previously reported in the biomedical research literature. Finally, we used a combination of topic modeling and nonlinear dimensionality reduction techniques to develop a model of multi-article fields within JHB. We found evidence for directional changes in the representation of fields on multiple scales. The diversity of JHB with regard to the representation of thematic fields has increased overall, with most of that diversification occurring in recent years. Drawing on the dataset generated in the course of this analysis, as well as web services in the emerging digital history and philosophy of science ecosystem, we have developed an interactive web platform for exploring the content of JHB, and we provide a brief overview of the platform in this article. As a whole, the data and analyses presented here provide a starting-place for further critical reflection on the evolution of the history of biology over the past half-century. (shrink)

This paper sets mathematics among the sciences, despite not being empirical, because it studies relations of various sorts, like the sciences. Each empirical science studies the relations among objects, which relations determining which science. The mathematical science studies relations as such, regardless of what those relations may be or be among, how relations themselves are related. This places it at the extreme among the sciences with no objects of its own (A Subject with no Object, by J.P. Burgess and G. (...) Rosen). Examples are discussed. The historical development of written mathematics from algorithms on clay tablets to theorems with proofs is said to show that application of algorithms to specific problems and theorems to scientific objects is like allegorical interpretation. Mathematics fits into the modern scientific context because the sciences, beginning with Galileo, have been constructed in imitation of mathematics. Viewing mathematics this way does not solve any ontological problems, but it does show how mathematics avoids them. Epistemological problems, insuperable for object realism, are simplified. For example, we have access to relations among any objects that we can consider objectively, first physical objects and then mathematical objects of greater and greater abstraction. (shrink)

Much speculation on the sources of Duhem's historical interests fails to account for the major shifts in these interests: neither his belief in the continuous development of physics nor his Catholicism, when his Church was encouraging the study of generally Aristotelian scholastic thought, led to any interest in mediaeval science before 1904. Equally, his own claim that he was merely testing his views on the nature of physical theory is easily squared only with earlier work with no trace of mediaeval (...) science. Behind this discontinuity lies a major crisis. Though not a positivist, Duhem had based all his work on assumptions acceptable to positivists. One of these, the sterility of the Middle Ages, was refuted by his chance discovery of evidence of genuine mediaeval science in the autumn of 1903, but that left the doctrine of scholastic sterility intact. (shrink)

Marcus Aurelius, Roman emperor from 161 to 180 A.D., is renowned for his just rule and long frontier wars. But his lasting fame rests on his Meditations, a bedside book of reflections and self-admonitions written during his last years, that provide unique insights into the mind of an ancient ruler and contain many passages of pungent epigram and poetic imagery. This study is designed to make the Meditations more accessible to the modern reader. Rutherford carefully explains the historical and philosophical (...) background, charts the main themes and tendencies of Marcus's thought, and relates stylistic detail to the intellectual and moral outlook of the author. His goal is to define Marcus's aims, attitudes, and styles more precisely and restore his work to the position it held in the past, that of a spiritual classic which can be read and enjoyed by people who are not professional scholars. (shrink)