RESUMEN Diversos estudios han concluido que los pacientes con daño en la Corteza Frontal -CF- o Corteza Prefrontal Ventromedial -CPV- muestran una disposición a herir directamente a otra persona con el fin de salvar varias vidas en sus respuestas a los "dilemas morales personales", revelando una posible carencia de empatía. No obstante, cuando evalúan conductas carentes de empatía sin justificación utilitarista, sus respuestas son normales. Defendemos aquí que los pacientes sufren una deficiencia cognitiva relacionada con la hipótesis de marcador somático (...) de Damasio y con juicios de valor. Criticamos la hipótesis del "paciente utilitarista", que se ha atrincherado en la neurociencia cognitiva. ABSTRACT In their answers to questions regarding "personal moral dilemmas", patients with lesions to the Frontal Cortex -FC- or Ventromedial Prefrontal Cortex -vmPFC- display a disposition to directly injure another person in order to save lives, thus revealing a possible lack of empathy. However, their answers are normal when they evaluate behaviors lacking in empathy but without a utilitarian justification. We here defend that those patients suffer from a cognitive deficiency associated with Damasio's somatic marker hypothesis and with value judgments. The article critiques the "utilitarian patient" hypothesis that has become deeply rooted in cognitive neuroscience. RESUMO Diversos estudos têm concluído que os pacientes com danos no Córtex Frontal (CF) ou Córtex Pré-frontal Ventromedial (CPV) mostram uma disposição a ferir diretamente a outra pessoa com o objetivo de salvar várias vidas em suas respostas aos "dilemas morais pessoais", o que revela uma possível carência de empatia. Contudo, quando avaliam condutas carentes de empatia sem justificativa utilitarista, suas respostas são normais. Defendemos aqui que os pacientes sofrem uma deficiência cognitiva relacionada com a hipótese de marcador somático de Damásio e com juízos de valor. Criticamos a hipótese do "paciente utilitarista", que vem se refugiando na neurociência cognitiva. (shrink)

Diversos estudios han concluido que los pacientes con daño en la Corteza Frontal –CF– o Corteza Prefrontal Ventromedial –CPV– muestran una disposición a herir directamente a otra persona con el fin de salvar varias vidas en sus respuestas a los “dilemas morales personales”, revelando una posible carencia de empatía. No obstante, cuando evalúan conductas carentes de empatía sin justificación utilitarista, sus respuestas son normales. Defendemos aquí que los pacientes sufren una deficiencia cognitiva relacionada con la hipótesis de marcador somático de (...) Damasio y con juicios de valor. Criticamos la hipótesis del “paciente utilitarista”, que se ha atrincherado en la neurociencia cognitiva. (shrink)

AimThe functional prognosis of patients after coma following either cardiac arrest or acute structural brain injury is often uncertain. These patients are associated with high mortality and disability. N20 and N70 somatosensory evoked potentials are used to predict prognosis. We evaluated the utility of SSEP as an early indicator of long-term prognosis in these patients.MethodsThis was a retrospective cohort study of patients admitted to the intensive care unit with a diagnosis of coma after CA or ABI. An SSEP study was (...) performed, including N20 and N70 at 24–72 h, after coma onset. Functional recovery was assessed 6–12 months later using the modified Glasgow scale. The study was approved by our local research ethics committee.ResultsIn the CA and ABI groups, the absence of N20 or N70 was a strong indicator of poor outcome. Conversely, the presence of N70 was an indicator of a good outcome.ConclusionSomatosensory evoked potentials are useful early prognostic markers with high specificity and sensitivity. Moreover, N70 has additional potential value for improving the prediction of good long-term functional outcomes.Clinical Trial Registration:[https://clinicaltrials.gov/], identifier [2018/01/001]. (shrink)

Una literatura creciente en neuropsicología estudia el juicio moral aplicando dilemas morales a personas con daños neuronales o con rasgos de personalidad antisocial; y parece confirmar una tendencia al juicio utilitarista contra-intuitivo, es decir, estas personas aprueban el sacrificio de un inocente para salvar varias vidas. Argumentamos que las evidencias encontradas no respaldan la hipótesis de dos módulos morales (Greene et al. 2004), sino más bien una disfunción en la capacidad empática o en el procesamiento de emociones, que apoyaría una (...) psicología moral de corte Humeano. Abogamos, además, por ampliar el explanandum: del juicio utilitarista contra-intuitivo al juicio moral contra-intuitivo sin más. Esto permitiría investigar experimentalmente un amplio rango de variables afectadas por disfunciones en la capacidad para la empatía. (shrink)

She was intensely sympathetic. She was immensely charming. She excelled in the difficult arts of family life. She sacrificed herself daily. If there was chicken, she took the leg, if there was a draught, she sat in it—in short, she was so constituted that she never had a mind or wish of her own, but preferred to sympathise always with the minds and wishes of others. — Virginia Woolf (1979, 59).

John Christman has argued that constitutively relational accounts of autonomy, as defended by some feminist theorists, are problematically perfectionist about the human good. I argue that autonomy is constitutively relational, but not in a way that implies perfectionism: autonomy depends on a dialogical disposition to hold oneself answerable to external, critical perspectives on one's action-guiding commitments. This type of relationality carries no substantive value commitments, yet it does answer to core feminist concerns about autonomy.

Right after our tragedy, my idea of forgiveness was to be free of this thing, – the anger, the pain, the absorption. It was totally personal. It was a survival tactic to leave this experience behind. It had nothing to do with the offender. The second level was realizing how the word forgiveness applies to the relationship between the victim and the offender. How it means accepting and working on that relationship after a murder. The latter is more complicated. Now (...) I think I see that forgiveness is more of integrating the experience into my life in a controlled way, rather than letting it go or escaping it. (shrink)

Both Aristotle and Kant note that the highest form of friendship enables individuals of good virtue to reveal themselves to one another. I argue that Aristotle and Kant emphasize complementary aspects of self-disclosure in friendship: whereas Kant acknowledges the inherent value of self-disclosure in friendship, Aristotle suggests that joint perception in friendship is instrumentally valuable in the acquisition of self-knowledge. I also argue that although Aristotle has a more developed account of friendship, Kant advances a superior account of self-disclosure in (...) friendship in his later remarks on friendship in the Metaphysical Principles of Virtue. (shrink)

This book develops the view that meaningful work is central in human flourishing. The author defends a pluralistic account of what makes work meaningful, arguing that work can be meaningful in virtue of developing capabilities, supporting virtues, providing a purpose, or integrating elements of a worker's life.

Citizen science models of public participation in scientific research represent a growing area of opportunity for health and biomedical research, as well as new impetus for more collaborative forms of engagement in large-scale research. However, this also surfaces a variety of ethical issues that both fall outside of and build upon the standard human subjects concerns in bioethics. This article provides background on citizen science, examples of current projects in the field, and discussion of established and emerging ethical issues for (...) citizen science in health and biomedical research. (shrink)

Clarifying the nature of possibility is crucial for an evaluation of the phenomenological approach to ontology. From a phenomenological perspective, it is ontological possibility, and not spatiotemporal existence, that has pre-eminent ontological status. Since the sphere of phenomenological being and the sphere of experienceability turn out to be overlapping, this makes room for two perspectives. We can confer foundational priority to the acts of consciousness over possibilities, or to pre-set possibilities over the activity of consciousness. Husserl’s position on this issue (...) seems to change over time. Ultimately, the establishment of a phenomenological perspective must involve a rejection of any hypostatization of pre-set possibilities, but not all implications of this theoretical step seem to be drawn in Husserl’s texts. This paper is devoted to an illustration of how the phenomenological notion of possibility should change when we reject the hypostatization of possibility, that is, when we reject the idea that all acts of consciousness are to be conceived as realizations of pre-set “ideal forms”. We examine this question, first, by trying to clarify the conceptual constellation of “possibility” in Husserl’s texts. This leads to an overall classification of the features of constituted possibilities. Then we distinguish such constituted possibilities from their constituting conditions, which outlines a different sense of “possibility”. In the last instance two “possibilizing” dimensions are shown to lie at the root of all ontic possibilities. This leads to a final suggestion on the nature of the relation between experience and possibility. Actual experiences create the room for possibility: they are possibilizations. In this sense, experience is to be taken as a generative sphere which goes beyond the customary boundary between epistemic and ontological. From this point of view all experience is to be conceived as emergence. (shrink)

In recent works, Časlav Brukner and Jacques Pienaar have raised interesting objections to the relational interpretation of quantum mechanics. We answer these objections in detail and show that, far from questioning the viability of the interpretation, they sharpen and clarify it.

Political theorists aiming to articulate normative standards for the EU have almost entirely focused on whether or not the EU suffers from a ‘democratic deficit'. Almost nothing has been written, by contrast, on one of the central values underpinning European integration since at least the European Coal and Steel Community (ECSC), namely solidarity. What kinds of principles, policies, and ideals should an affirmation of solidarity commit us to? Put another way: what norms of socioeconomic justice ought to apply to the (...) EU? This is not an empirical or narrowly legal question. We are not trying to gauge the degree of attachment there currently is in the EU by, for example, citing the latest Eurobarometer poll. We are also not attempting to state the implicit rationale followed by the Court of Justice in its recent ‘solidarity’ jurisprudence, let alone trying to fix what the Commission might mean by it. In this article, I ask the more fundamental question underlying both the legal and the empirical questions: What principles of social solidarity ought to apply between states and citizens of the emerging European polity? This question has rarely been asked or answered by political theorists in an EU context, so we are entering largely uncharted territory. The article develops a tripartite model of EU solidarity in Section 2, and then applies it to the case of free movement of persons in Section 3. (shrink)

Masked priming experiments occasionally revealed surprising effects: Participants responded slower for congruent compared to incongruent primes. This negative congruency effect was ascribed to inhibition of prime-induced activation [Eimer, M., & Schlaghecken, F. . Response faciliation and inhibition in subliminal priming. Biological Psychology, 64, 7–26.] that sets in if the prime activation is sufficiently strong. The current study tests this assumption by implementing manipulations designed to vary the amount of prime-induced activation in three experiments. In Experiments 1 and 3, NCEs were (...) observed despite reduced prime-induced activation. Experiment 2 revealed no NCE with at least similar prime strength. Thus, the amount of prime activation did not predict whether or not NCEs occurred. The findings are discussed with regard to the inhibition account and the recently proposed account of mask-induced activation [cf. Lleras, A., & Enns, J. T. . Negative compatibility or object updating? A cautionary tale of mask-dependent priming. Journal of Experimental Psychology: General, 133, 475–493; Verleger, R., Jaskowski, P., Aydemir, A., van der Lubbe, R. H. J., & Groen, M. . Qualitative differences between conscious and nonconscious processing? On inverse priming induced by masked arrows. Journal of Experimental Psychology: General, 133, 494–515]. (shrink)

In this paper I criticize Claude Romano’s recent characterization of Husserl’s phenomenology as a form of Cartesianism. Contra Romano, Husserl is not committed to the view that since individual things in the world are dubitable, then the world as a whole is dubitable. On the contrary, for Husserl doubt is a merely transitional phenomenon which can only characterize a temporary span of experience. Similarly, illusion is not a mode of experience in its own right but a retrospective way of characterizing (...) a span of experience. Therefore, Husserl cannot be plausibly characterized as either a disjunctivist or a conjunctivist. The common premise of both theories – namely, that perception and illusion are two classes of conscious acts standing on equal footing – is phenomenologically unsound. I propose to call Husserl’s theory a hermeneutical theory of perception, i.e., one that interprets perception as a temporal and self-correcting process. In the last part of the paper I argue that Husserl’s positive appraisal of Cartesian doubt is only pedagogical in nature. Husserl does not take Cartesian doubt to be practicable, but the attempt to doubt universally has the positive effect of revealing transcendental subjectivity as the subject matter of phenomenology. (shrink)

How many logics do logical pluralists adopt, or are allowed to adopt, or ought to adopt, in arguing for their view? These metatheoretical questions lurk behind much of the discussion on logical pluralism, and have a direct bearing on normative issues concerning the choice of a correct logic and the characterization of valid reasoning. Still, they commonly receive just swift answers – if any. Our aim is to tackle these questions head on, by clarifying the range of possibilities that logical (...) pluralists have at their disposal when it comes to the metatheory of their position, and by spelling out which routes are advisable. We explore ramifications of all relevant responses to our question: no logic, a single logic, more than one logic. In the end, we express skepticism that any proposed answer is viable. This threatens the coherence of current and future versions of logical pluralism. (shrink)

In the current debate on theodicy, the problem of animal suffering is becoming increasingly relevant, as demonstrated by some recent books devoted to this topic. Such a problem is particularly challenging for a theistic theodicy, as its traditional arguments do not seem able to deal with it. In the first instance, the article aims to provide a brief overview of the main arguments sustained by theists regarding animal suffering, and secondly to provide an evaluation of such arguments which might be (...) useful for further research on this topic. (shrink)

In this paper I develop a conception of joint practical deliberation as a special type of shared cooperative activity, through which co-deliberators jointly accept reasons as applying to them as a pair or group. I argue, moreover, that the aspiration to deliberative “pairhood” is distinguished by a special concern for mutuality that guides each deliberator’s readiness to accept a given consideration as a reason-for-us. It matters to each of us, as joint deliberators, that each party’s (individual) reasons for accepting something (...) as a reason-for-us support a conception of our relationship as one characterized by mutual, non-instrumental concern for one another. (shrink)

Much research has focused on the effects of pathogenic mitochondrial mutations on health. Notwithstanding, the mechanisms regulating the link between these mutations and their effects remain elusive in several cases. Here, we propose that certain mitochondrial mutations may disrupt function of a set of mitochondrial‐transcribed small RNAs, perturbing communication between mitochondria and nucleus, leading to disease. Our hypothesis synthesises two lines of supporting evidence. First, several mitochondrial mutations cannot be directly linked to effects on energy production or protein synthesis. Second, (...) emerging studies have described the existence of small RNAs encoded by the mitochondria and proposed their involvement in RNA interference. We present a roadmap to testing this hypothesis. (shrink)

Many arguments are affected by context sensitivity, because they include sentences that have different truth conditions in different contexts. Therefore, it is natural to think that a general criterion for evaluating arguments must take context sensitivity into account. One way to give substance to that thought is provided by the definition of validity offered by David Kaplan within his theory of indexicals. However, the route indicated by Kaplan is hindered by a problem whose importance is often underestimated. This paper explores (...) a different route, and outlines a definition of validity that does not run into that problem. Its moral is that Kaplan's definition is not the only plausible definition. This is not to say that the definition outlined is the only plausible definition or that it is correct in some absolute sense. There might be equally important problems with it that the paper does not take into account. But until such problems are found and brought up, the departure from Kaplan's route remains a viable option. (shrink)

This study investigates the extent to which there is individuality in how structural variation is conditioned over time. Earlier research already classified the diachronically unstable gerund variation as involving a high fraction of mixed-usage speakers throughout the change, whereby the proportion of the conservative variant versus the progressive variant as observable in the linguistic output of individual language users superficially resembles the mean proportion as observable at the population level. However, this study sets out to show that there can still (...) be heterogeneity within such a centralized population in terms of how each individual conditions the observed variation. A random forest and conditional inference tree analysis of over 14,000 gerunds uttered by nineteen seventeenth-century authors is presented to show that, while the most important language-internal factors conditioning the gerund variation are adopted by (and shared between) all authors, we can still attest inter-individual variation (i) at lower levels of variable importance, and (ii) in the breadth of the range of contexts individual authors employ to condition the attested variation. (shrink)

This paper reports on the findings of a qualitative study to understand how active adherence to the Christian faith influences the way SME owner-managers conceptualise their business practices. The study was based on in-depth interviews with 21 Christian SME owner-managers in Germany and the UK. Using a socio-psychological approach, the data analysis yielded a range of linguistic and conceptual resources that are peculiar to Christian discourse and that have the potential to influence business activity in rather distinctive ways. This paper (...) particularly focuses on those Christian concepts that could be regarded as distinct 'frames' for action. It outlines what effect these concepts had on the respondents and how they were related to business practices. The paper also discusses how this study could inform further research into the influence of other socio-cultural forms of identity on economic actors' conceptualisations of their own practice. (shrink)

Most contemporary chemists consider quantum mechanics to be the foundational theory of their discipline, although few of the calculations that a strict reduction would seem to require have ever been produced. In this essay I discuss contemporary algebraic and diagrammatic representations of molecular systems derived from quantum mechanical models, specifically configuration interaction wavefunctions for ab initio calculations and molecular orbital energy diagrams. My aim is to suggest that recent dissatisfaction with reductive accounts of chemical theory may stem from both the (...) inability of standard accounts of reduction to incorporate the diverse forms of representation found in chemical practice and our philosophical predilection to analyze all connections between theories in terms of logical reduction. (shrink)

Some works of architecture have remarkable aesthetic value. According to certain philosophers, part of this value derives from the appearance of such constructions to fulfil the function for which they were built. I argue that one way of understanding the connection between function and aesthetic value resides in the concept of functional beauty. I analyse a number of recent accounts of this notion, then offer a better way of understanding it. I then focus my attention on the relation between aesthetic (...) and moral values and claim that, if the notion of functional beauty makes any sense at all, then we have a pro tanto case for holding that moral defects in works of architecture can have aesthetic merits. (shrink)

In order to accommodate for the present shortage of oocyte donors, oocyte-donation programs place ads in college newspapers and provide large monetary compensation to encourage participation. Large compensation acts as a strong incentive for young women to undergo the potentially risky procedure of donation. In this enticing situation, it is particularly important for programs to fully inform prospective donors of the risks of the procedure so that they can accurately weigh the costs and benefits of donating. However, because oocyte-donor programs (...) must alleviate the shortage of donors if they wish to maintain a financially viable business, there is reason to fear that they may minimize or misrepresent risks when recruiting egg donors. In this pilot study, the risk information provided by programs (n=19) to prospective oocyte donors in a preliminary phone call inquiry was investigated. The majority of the programs provided incomplete and/or inaccurate risk information. Policy changes are recommended to reduce the potential for undue influence and to standardize and regulate the risk information provided to prospective egg donors. (shrink)

En este estudio analizamos recursos conceptuales alternativos a los que se han delimitado desde el marco de cognición dominante que configuró el canon académico occidental tradicional, para resignificar nuestras prácticas epistémicas y de subjetivación, con el objetivo de reconocer y legitimar, dentro de las narraciones acerca del conocimiento, las experiencias de identidades disidentes frente a la hegemonía. Para ello, examinamos cómo los espacios de producción de conocimiento normativos han mantenido una semiótica cerrada excluyendo los saberes de subjetividades periféricas. En este (...) contexto, acudimos a las propuestas de la comprensión encarnada y el conocimiento situado para entablar diálogos encarnados-situados desde los que ofrecer perspectivas alternativas y críticas respecto a las prácticas epistémicas. Desde estos diálogos, estudiamos la cuestión de la subjetividad a través de la idea de diferencia para ofrecer horizontes más flexibles y abiertos respecto a la configuración identitaria, en un sentido tanto individual como colectivo. (shrink)

This article, divided into two parts, traces and discusses two pairs of analogies invoked in Sanskrit literature to articulate the paradox of God’s oneness and multiplicity vis-à-vis the souls and the manifest world, reflecting the philosophical positions of pariṇāmavāda and vivartavāda. These are, respectively, the analogies of fire in wood and dairy products in milk, and moon/sun in pools of water and space in pots. In Part I, having introduced prevalent ideas about the status of the supreme principle vis-à-vis creation (...) in Śaivism, Sāṅkhya, and Vedānta, I investigate instances of the first pair of analogies in multiple textual genres, and especially in Śaiva literature from South and Southeast Asia, to highlight the influence of pariṇāma-Vedānta on the Śaiva textual corpus. Arguing that the distribution of the two pairs of analogies may cast some light on the relationship between different strands of dualistic and non-dualistic scriptures, I propose that the first pair could be traced back to the “formative” period of Śaivism—that is, prior to the emergence of the fully dualistic Śaiva Saiddhāntika corpus known to us. (shrink)

Larry Shiner iniciadas a principios del siglo XVIII tienen, en el pensamiento filosófico, una tradición un tanto más antigua pues, aun cuando no existía una pregunta explícita sobre qué es el arte, había, ya desde Platón, una profunda reflexión respecto a la creación artística, así como sobre el papel que el artista y su obra desempeñaban dentro de su sociedad, papel que para el filósofo adquiría un carácter negativo cuando se ocupaba de la imitación de las formas o ideas verdaderas; (...) es decir, cuando se trataba del arte imitativo, ya que al ser el mundo una copia de dichas ideas y, a su vez, ser esta copia la representada por el artista en su obra, esta última sería, entonces, la copia de una copia, la representación de algo que ya de por sí no es verdadero. (shrink)

Name der Zeitschrift: Byzantinische Zeitschrift Jahrgang: 110 Heft: 3 Seiten: 673-690.