Purpose: This study is aimed to preliminary investigate whether transcranial alternating current stimulation could affect explosive power considering genetic background in sport subjects.Methods: Seventeen healthy sports volunteers with at least 3 years of sports activities participated in the experiment. After 2 weeks of familiarization performed without any stimulation, each participant received either 50 Hz-tACS or sham-tACS. Before and after stimulation, subjects performed the following tests: the squat jump with the hands on the hips ; countermovement jump with the hands on (...) the hips ; countermovement jump with arm swing ; 15-s Bosco’s test; seated backward overhead medicine ball throw ; seated chest pass throw with a 3-kg rubber medicine ball; and hand-grip test. Additionally, saliva samples were collected from each participant. Genotyping analysis was carried out by polymerase chain reaction.Results: No significant differences were found in sport performance of subjects after 50 Hz-tACS. Additionally, we did not find any influence of genetic background on tACS-related effect on physical performance. These results suggest that tACS at gamma frequency is not able to induce an after-effect modulating sport performance. Further investigations with larger sample size are needed in order to understand the potential role of non-invasive brain stimulation techniques in motor performances.Conclusions: Gamma-tACS applied before the physical performance fails to improve explosive power in sport subjects. (shrink)

Despite that it is commonly accepted that migraine is a disorder of the nervous system with a prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies have found bidirectional comorbidity between migraine and different disorders including neurological, psychiatric, cardio- and cerebrovascular, gastrointestinal, metaboloendocrine, and immunological conditions. Each of these has its own genetic load and shares some common characteristics with migraine. The bidirectional mechanisms that are likely to underlie this extensive comorbidity between migraine and other (...) diseases are manifold. Comorbid pathologies can induce and promote thalamocortical network dysexcitability, multi-organ transient or persistent pro-inflammatory state, and disproportionate energetic needs in a variable combination, which in turn may be causative mechanisms of the activation of an ample defensive system with includes the trigeminovascular system in conjunction with the neuroendocrine hypothalamic system. This strategy is designed to maintain brain homeostasis by regulating homeostatic needs, such as normal subcortico-cortical excitability, energy balance, osmoregulation, and emotional response. In this light, the treatment of migraine should always involves a multidisciplinary approach, aimed at identifying and, if necessary, eliminating possible risk and comorbidity factors. (shrink)

Nell'agosto del 1462 papa Pio II investiva il cardinale Bessarione di Nicea della commenda del monastero di Grottaferrata, che succedeva al calabrese Pietro Vitali, ultimo degli egumeni de regimine, eletto a capo dell'Archimandritato di Messina. Uno dei primi atti di governo di Bessarione fu di incaricare l'arcivescovo di Siponto Niccolò Perotti, quale suo procuratore, di procedere ad una dettagliata ricognizione dei beni mobili e immobili del monastero criptense. I relativi inventari ci sono pervenuti nei mss. Grottaferrata Z. δ. XII (...) (ff. 1-63) per i beni immobili, e Grottaferrata, Archivio del Monumento Nazionale, 523 (ff. 105-116) per i beni mobili. Nei ff. 108v-110 di quest'ultimo documento, la cui redazione era stata affidata dal Perotti al notaio Stefano Tegliati (o Tegliazio), si trova il primo sommario elenco conosciuto dei libri manoscritti della biblioteca, pubblicato da Pierre Batiffol e poi da Antonio Rocchi. Vi risultano 114 manoscritti greci, 2 latini e «circa viginti volumina librorum sine principio et mala ordinata». (shrink)

Damasio, an eminent neuroscientist explores the science of human emotion and what the great Dutch philosopher Baruch Spinoza can teach of how and why we feel. Damasio shows how joy and sorrow, those most defining of human feelings, are in fact the cornerstones of our survival and culture.

This article is an introduction to the selection of papers on "Business Ethics in Spain" included in this monographic issue of the Journal of Business Ethics. Specifically, this article is a survey of the development of the social, political, cultural and economic background of business in Spain since 1940, in order to show how the ethical values, attitudes and problems of the Spanish managers changed in these years. First, the global evolution of this background is explained, and then several relevant (...) problems are discussed, namely those of the attitudes of business towards the State and the law (with an aside on the attitudes of society towards profit and wealth), corruption, and the grey economy, taxes, and irregular labour. The article concludes with a survey of the scientific developments of business ethics in Spain. (shrink)

This paper develops the very basic notions of analysis in a weak second-order theory of arithmetic BTFA whose provably total functions are the polynomial time computable functions. We formalize within BTFA the real number system and the notion of a continuous real function of a real variable. The theory BTFA is able to prove the intermediate value theorem, wherefore it follows that the system of real numbers is a real closed ordered field. In the last section of the paper, we (...) show how to interpret the theory BTFA in Robinson's theory of arithmetic Q. This fact entails that the elementary theory of the real closed ordered fields is interpretable in Q. (shrink)

The paper presents a metaphysical characterization of spatiotemporal backgrounds from a realist perspective. The conceptual analysis is based on a heuristic sketch that encompasses the common formal traits of the major spacetime theories, such as Newtonian mechanics and general relativity. It is shown how this framework can be interpreted in a fully realist fashion, and what is the role of background structures in such a picture. In the end it is argued that, although backgrounds are a source of metaphysical discomfort, (...) still they make a spacetime theory easy to interpret. It is also suggested that this conclusion partially explains why the notion of background independence carries a lot of conceptual difficulties. (shrink)

In the Transcendental Aesthetic, Kant famously characterizes space as a unity, understood as an essentially singular whole. He further develops his account of the unity of space in the B-Deduction, where he relates the unity of space to the original synthetic unity of apperception, and draws an infamous distinction between form of intuition and formal intuition. Kant ’s cryptic remarks in this part of the Critique have given rise to two widespread and diametrically opposed readings, which I call the Synthesis (...) and Brute Given Readings. I argue for an entirely new reading, which I call the Part-Whole Reading, in part by considering the development of Kant ’s views on the unity of space from his earliest works up through crucial reflections written during the silent decade. (shrink)

This article seeks to problematize Agamben’s interpretation of sovereignty in light of the “archaeological method” he uses in his Homo Sacer project. In contrast to Agamben’s exposition, which treats biopolitics as the original and ontological paradigm of Western politics, the essay discusses how, historically, sovereign power has been conceived as a “double body”—transcendent and immanent, sacred and sacrificial, absolute and perpetual—from whose tension conceptual and political metamorphoses of sovereignty arise. The first attribute of sovereignty—absoluteness, on which Agamben has often focused—should (...) be seen as an ordering and essentially modern function of its second “body”: the perpetuity of power. The article illustrates, then, how the retrospective projections through which the Italian philosopher constructs his ontological reading of sovereignty depend on some logical and epistemological lacunae that characterize his “archaeological method,” which is based, essentially, on an arbitrary use of historical analogies. (shrink)

Several fields of research associated with the history of the early modern Iberian world have experienced a significant boost in recent decades: Iberian science as it relates to the Atlantic world, the history of European colonial empires, and the study of knowledge production in Latin American cultures. This expansion has coincided with a renewed interest of historians of the early modern period in practical knowledge and artisanal cultures. This paper presents an updated historiographic review of both lines of research as (...) well as of their close interconnections. In addition, it offers a re-interpretation of Iberian imperial science in the context of the European maritime expansion through the lens of artisanal epistemology. (shrink)

No presente artigo começo fazendo considerações sobre a história das inovações de desenvolvimentos genéticos, abordando as questões relativas ao descobrimento e elucidação do DNA, sobre a influência da genética para o pensamento evolucionista, a decodificação do genoma humano, a técnica DGPI e também sobre o CRISPR-Cas9. Depois, o texto passa a ter um tom mais filosófico, donde exponho e reflito a partir da perspectiva habermasiana em Sobre o futuro da natureza humana: a caminho de uma eugenia liberal? – Nesse sentido, (...) minhas reflexões são especialmente sobre a relação entre a estética e a eugenia e também sobre a responsabilidade moral dos indivíduos geneticamente modificados, precisamente pensados na esfera e hipótese da eugenia positiva. (shrink)

Water values serve as an entry point into the intricacies of public policies and management approaches. Values are contingent assessments that emerge out of socio-ecological relations and reflect particular demands, legacies and opportunities. The concept of value positionality is introduced as the synthesis of multiple expressions of worthiness cherished by a social group. Positionality is a metaphor that connects the phenomenological understanding of water value with the politics of everyday life and the broader politico-institutional framework. It entails a cluster of (...) meanings expressed through territorialised interactions across time, locations and scales. Positionalities converge or depart according to value praxis, that is, the clash of competing valuation approaches seeking legitimisation. (shrink)

Heidegger tries to explain our emotional life applying three schemes: causal explanation, mental internalisation of emotions and metaphorical expression. None of the three schemes explains emotion though. Either because the causal nexus does not always occur or because objects and people in the external world are carriers of emotional agents or because language is already on a metaphorical level. Moreover, how is it possible that there are presently emotions constituting our life without our being aware of their existence? From the (...) analysis of boredom in its three varieties (“bored by X”, “get oneself bored”, and “it is boring”) we will get to the depth where emotions lie, trying to rouse them and to keep them awake. Although it surfaces with the force and energy of the present, every emotion has its past and future constitution. How can we understand the future of a present emotion along with its past? (shrink)

Resumo: O objetivo do presente artigo é analisar o problema da fraqueza da vontade no quadro conceitual da filosofia moral kantiana. A fim de realçar uma característica da filosofia kantiana relevante para a posição conceitual do problema, servimo-nos do contraste com as análises de Donald Davidson sobre o fenômeno da fraqueza da vontade. Depois de evidenciado o modo como o fenômeno pode ser admitido no sistema kantiano, procuramos defender uma hipótese quanto ao modo como ele poderia ser aí explicado. Trata-se (...) da hipótese de que uma derivação desatenta e negligente a partir da Lei Moral poderia tornar compreensíveis os diversos estágios da maldade em sentido amplo do ser humano, e de que os dois primeiros estágios poderiam ser considerados correspondentes ao fenômeno usualmente chamado de fraqueza da vontade.Abstract: The aim of the present paper is to examine the problem of weakness of will in the conceptual framework of Kantian's moral philosophy. In order to present a feature of Kantian's philosophy which is important for the theoretical placing of the problem, I draw on the contrast with Davidson's analyses of the phenomenon of weakness of will. After indicating the way in which the phenomenon can be admitted in the Kantian system, I try to defend a hypothesis about the way in which it could be explained in this system. It is the hypothesis that an inattentive and negligent derivation from the Moral Law could explain the different stages of the evilness in broad sense of the human being, and that the two first stages can be judged correspondent to the phenomenon usually called weakness of will. (shrink)

In this paper I will present an analysis of the impact that the notion of “bounded rationality”, introduced by Herbert Simon in his book “Administrative Behavior”, produced in the field of Artificial Intelligence (AI). In particular, by focusing on the field of Automated Decision Making (ADM), I will show how the introduction of the cognitive dimension into the study of choice of a rational (natural) agent, indirectly determined - in the AI field - the development of a line of research (...) aiming at the realisation of artificial systems whose decisions are based on the adoption of powerful shortcut strategies (known as heuristics) based on “satisficing” - i.e. non optimal - solutions to problem solving. I will show how the “heuristic approach” to problem solving allowed, in AI, to face problems of combinatorial complexity in real-life situations and still represents an important strategy for the design and implementation of intelligent systems. (shrink)

The concept of authenticity as a predicate of performances of musical works is discussed in the context of the Western classical tradition.I claim that the concept of a performance of a musical work raises issues of relativity and indeterminacy, since its application is not completely free from music-historical contextuality and from considerations of aesthetic value.I challenge the argument for the necessity of authenticity in performance that eschews the problem of determining the extension of the concept authentic performance of a work' (...) by reducing the concept to that of the correct instantiation of that work.I suggest that the way the present socio-musical context defines the boundaries of correction and authenticity in performance derives from a balance, and a tension, between two types of interest in performance as an artistic practice: an interest in the performed work as the artistic product of its composer, which favours fidelity to the work; and an interest in the performance as the artistic product of the performer, which favours the latter's creative freedom.I argue for the relevance of certain moral obligations to composers on the part of performers, but also for the defeasible character of these obligations, thus blocking the view according to which historical authenticity is an absolute moral imperative.I distinguish personal authenticity, as creativity and sincerity on the part the performer, from historical authenticity, as the performance's faithfulness to the work performed, to its composer, or to the sound, performance practice or musical experience that were typical of the work's original context. I argue against the view that the historically authentic performance has an advantage over other kinds of performance in terms of propensity to generate more aesthetically successful results.The promotion of historical authenticity by the historically informed performance movement is analyzed as artistic ideology and practice. I conclude that the priority of historical authenticity is not a defensible artistic ideal, since it is ultimately incompatible with aesthetic priorities. (shrink)

o presente artigo objetiva abordar acerca da crítica consistente ao autoritarismo violento, degradante, racista e desumano dos “anos de chumbo” da ditadura militar no Brasil, constante na literatura afro-brasileira dramática negro-brasileira a partir, sobretudo, de três teatros peculiares, a saber: o Teatro Experimental Negro, o Teatro Profissional do Negro e o Grupo Teatro Palmares Iñaron. Metodologicamente, esclarece-se que esta escrita emprega uma abordagem qualitativa de natureza básica e é de cunho teórico exploratório quanto ao objetivo principal, pois se debruça ao (...) debate, visando aprimorar teorias, conceitos e ideias a partir do bojo de fontes secundárias que tratam da temática principal. Neste sentido, empregou-se o método procedimental bibliográfico utilizando-se da hermenêutica com a técnica de leituras pertinentes à temática proposta. Cabe salientar que, apesar da tentativa histórica do cânone da literatura autoritária e eurocentrada, não foi e nem tem sido capaz de silenciar os ecos objetivos e/ou subjetivos expressos na literatura afro-brasileira, nem mesmo durante o período mais duro e racista da ditadura militar no Brasil. (shrink)

La conmemoración, en el año 2017 del cuarto Centenario de la muerte de Francisco Suárez, constituye un motivo cultural que invita a repensar la persistencia de su legado doctrinal jurídico en la Filosofía y la Teoría del Derecho de la actualidad. En este ensayo se analizan su concepción de la ley, a partir de sus elementos constitutivos y de sus implicaciones. Así como las relevantes observaciones de Suárez sobre las características del lenguaje lega. Este trabajo se propone ofrecer un balance (...) de aquellos aspectos de la reflexión de Francisco Suárez sobre el Derecho que pueden implicar mayor interés para la cultura jurídica del presente. Se analiza, con especial atención, el carácter innovador de la concepción jurídica de Suárez con respecto a la tradición medieval y a las doctrinas de su tiempo. Se pueden advertir así rasgos anticipadores del pensamiento de Suárez con respecto a determinadas concepciones filosófico-jurídicas contemporáneas. (shrink)

I elaborate and defend a "necessitarian" interpretation of Kant's account of laws.

El propósito de este trabajo consiste en exponer las tareas más apremiantes que, a juicio del autor, debe asumir la Filosofía del Derecho del presente y del inmediato futuro. Para ello, se analizan las dos tareas que se consideran de interés prioritario: la primera versa en torno a lo que entraña el desafío tecnológico propio de la sociedad digital que habitamos y que se concreta en la respuesta que desde la filosofía jurídica debe avanzarse respecto a la omnipresencia en todos (...) los ámbitos sociales, económicos, políticos, culturales y jurídicos de la Inteligencia Artificial (IA). Hace referencia la segunda al riesgo cultural que entraña la pretensión de determinados movimientos que se autoconsideran portavoces de los signos del universo tecnológico y los desarrollos de la tecnociencia, para inferir la propuesta ideológica del final del humanismo y el inicio de la era posthumanista. El trabajo concluye asignando a la Filosofía del Derecho la función de ser la conciencia de la IA que es Inteligencia sin conciencia; y de reivindicar la persistente necesidad de respetar y realizar los valores humanistas frente a su pretendida abolición por el posthumanismo. (shrink)

Badiou and Derrida have dedicated much of their thought to politics and the nature of the political. Calcagno shows how their views diverge and converge, providing some very intriguing developments in Continental philosophy.

Until now, the mass spread of fake news and its negative consequences have implied mainly textual content towards a loss of citizens' trust in institutions. Recently, a new type of machine learning framework has arisen, Generative Adversarial Networks (GANs) – a class of deep neural network models capable of creating multimedia content (photos, videos, audio) that simulate accurate content with extreme precision. While there are several areas of worthwhile application of GANs – e.g., in the field of audio-visual production, human-computer (...) interactions, satire, and artistic creativity – their deceptive uses, at least as currently foreseeable, are just as numerous and worrying. The main concern is linked to the so-called “deepfakes”, fake images or videos that simulate real events with extreme precision. When trained on a human face, GANs can make the face assume hyper-realistic movements, expressions and (verbal and non-verbal) communication abilities. This technology poses an urgent threat to the governance of democratic processes concerning the production of public opinions and political discourses, with significant potential for reality-altering and disinformation. After a short introduction of their current technical state-of-the-art, in this paper we want to enquire the GANs` socio-technical system alongside different and intertwined philosophical accounts. Firstly, we will argue about the conditions that make perceived a GANs-generated content as trustworthy, arguing also about the general effects GANs might have on the perceived trustworthiness of individuals. Thereafter, we will discuss about the inadequacy to approach GANs only as perception-altering technology. Against this backdrop, we will propose a theoretical turn that considers the human-machine relationships of trustworthiness as elements of a broader hybrid socio-technical systems. This turn come up with political repercussions that we will discuss in the last part of the paper. (shrink)

In this paper I aim to elucidate Wittgenstein’s claim that the so-called dream argument is senseless. Unlike other interpreters, who understand the sentence “I am dreaming” as contradictory or self-defeating, I intend to elucidate in what sense one should understand it as senseless or, more precisely, as nonsensical. In this sense, I propose to understand the above-mentioned claim in light of Wittgenstein’s criticism of skepticism from the _Tractatus logico-philosophicus_ to his last writings. I intend to show that the words “I (...) am dreaming” are nonsensical in the same sense as the alleged proposition “There are physical objects” or the expression of doubt about the existence of external objects. (shrink)

In the order of beingness, duty is a state much closer to Dasein than any form of rationality could be. The true duty and the true respect for the golden rule can only come from the authenticity of one’s beingness. The same goes for what we call humility. This duty, as an existential state, is a movement of the spirit which seems to be overwhelmed by the care for the Other, towards the Other. Any duty which does not “move the (...) being”, and which results, for example, from reason, is unauthentic and, viewed from a phenomenological perspective, it means the alienation of the appreciative capacity of the beingness - understood as Dasein. As such, appreciative ethics can only be placed at the crossroads between constructionism - as a theory on the agreed existence, and the phenomenology which enables the understanding of the subjective experience of the process of social construction of reality itself. (shrink)

This chapter discusses the question of whether we will ever have an Artificial General Superintelligence (AGSI) and how it will affect our species if it does so. First, it explores various proposed definitions of AGSI and the potential implications of its emergence, including the possibility of collaboration or conflict with humans, its impact on our daily lives, and its potential for increased creativity and wisdom. The concept of the Singularity, which refers to the hypothetical future emergence of superintelligent machines that (...) will take control of the world, is also introduced and discussed, along with criticisms of this concept. Second, it is considered the possibility of mind uploading (MU) and whether such MU would be a suitable means to achieve (true) immortality in this world—the ultimate goal of the proponents of this approach. It is argued that the technological possibility of achieving something like this is very remote, and that, even if it were ever achieved, serious problems would remain, such as the preservation of personal identity. Third, the chapter concludes arguing that the future we create will depend largely on how well we manage the development of AI. It is essential to develop governance of AI to ensure that critical decisions are not left in the hands of automated decision systems or those who create them. The importance of such governance lies not only in avoiding the dystopian scenarios of a future AGSI but also in ensuring that AI is developed in a way that benefits humanity. (shrink)

En los últimos años han adquirido especial relevancia dentro de la filosofía jurídica las teorías cosmopolitas. El cosmopolitismo supone una propuesta de gran potencial para insuflar nuevas fuerzas al ideal liberal democrático, debilitado ante los desafíos que presenta la globalización. Aunque los enfoques cosmopolitas actuales son valiosos, requieren complementarse con un análisis de las dinámicas de poder y control existentes en la sociedad tecnológica actual. La vía que se propone para ello es considerar las contribuciones recientes de Byung-Chul Han en (...) torno al concepto de psicopolítica. Han explica cómo la lógica del capitalismo neoliberal tardío logra mediante la tecnología someter al individuo a una nueva forma de control, cuestionando el carácter emancipatorio del proceso de globalización y señalando un aspecto pendiente de estudio en los debates acerca del valor actual del ideal cosmopolita. A partir de las teorías de Han es posible formular propuestas para fortalecer el cosmopolitismo. (shrink)