The complexity of biobank research raises concerns about individuals’ understanding of the information conveyed in the consent process for such research.. We report the results of a qualitative, cognitive interview study with an ethnically, linguistically, and educationally diverse sample of 43 respondents to assess the clarity and utility of a multimedia tool developed for a biobank. Using weighted randomization, respondents were assigned to either view the multimedia tool or read a written consent document . The study illustrates the utility of (...) cognitive interviews for gaining insights from prospective research participants about the clarity of informed consent tools. Findings suggest that a multimedia tool is useful for communicating key messages but should be combined with a written consent document and personal interaction with the study staff. We recommend that the potential value of multimedia tools should be more rigorously tested in a randomized controlled trial. (shrink)

The structure of natural languages is usually studied from three major different but interconnected points of view: syntax, semantics, and pragmatics. If we consider that the main purpose of natural languages is communication, we should consider another dimension for languages, which deals with the influence of internal states of communicating individuals on meanings. Such a dimension we refer to as internalism. Within this context, internalism cannot be confused with psycholinguistics, in the same way pragmatics cannot be confused with sociolinguistics. In (...) particular, we argue, language is tied to its systematic use. This view leads us to a non-realist perspective on linguistics. We analyze the role of natural languages into dialogues, by comparing our proposal to the dialogical approach to logic, which considers a dialogue as a game. Within our approach, there is no way to guarantee that two parties involved in a dialogue are playing the same game, due to unavoidable differences in their respective internal states. Another contribution of this paper is to argue that semantics plays a more fundamental role than syntax in the cognitive acquisition of languages. (shrink)

David Hume is one of the most provocative philosophers to have written in English. His Dialogues ask if a belief in God can be inferred from what is known of the universe, or whether such a belief is even consistent with such knowledge. The Natural History of Religion investigates the origins of belief, and follows its development from polytheism to dogmatic monotheism. Together, these works constitute the most formidable attack upon religious belief ever mounted by a philosopher. This new edition (...) includes Section XI of The Enquiry Concerning Human Understanding and a letter by Hume in which he discusses Dialogues. (shrink)

The first point that Tacitus makes is the confusion that surrounded these elections. Tiberius' policy was in no way as well denned here as it apparently was in the case of the praetorship elections: De comitiis consularibus, quae turn primum illo principe ac deinceps fuere, vix quicquam firmare ausim: adeo diversa non modo apud auctores, sed in ipsius orationibus reperiuntur.

The role of chance in historiography is a major question for the analysis of cultural transformations. Its main subject are the transformations of contingentia itself, which has undergone substantial changes in its mythical forms (as Tyche or Fortuna) as well in its historical expressions in philosophy, theology, politics, sciences, literature and art.

We study the intersection number of families of tall ideals. We show that the intersection number of the class of analytic P-ideals is equal to the bounding number ${\mathfrak{b}}$ , the intersection number of the class of all meager ideals is equal to ${\mathfrak{h}}$ and the intersection number of the class of all F σ ideals is between ${\mathfrak{h}}$ and ${\mathfrak{b}}$ , consistently different from both.

The Three Papers comprising this series, together with my earlier [34] also published in this journal, constitute an attempt to set out the major issues in the theoretical domain of reduction and to develop a general theory of theory reduction. The fourth paper, [34], though published separately from this trio, is integral to the presentation and should be read in conjunction with these papers. Even so, the presentation is limited in scope – roughly, to intertheoretic reduction among empirical theories – (...) and informal in presentation – not least because a satisfying formal account of theories has yet to be offered. And despite the length, the treatment is still condensed; often corroborating and/or intuitively helpful detail has had to be consigned to footnotes or omitted. I approach the problem from within my own naturalistic realist philosophy of science and formal analysis of abstract hierarchy in theory. The sources for the former are [25], [29], [31], and [32] and those for the latter essentially [27] and [30]. Hierarchical notions played a significant role in the already published [34]. (shrink)

The role of interaction in learning is essential and profound: it must provide the means to solve open problems (those only vaguely specified in advance), but cannot be captured using our familiar formal cognitive tools. This presents an impasse to those confined to present formalisms; but interaction is fundamentally dynamical, not formal, and with its importance thus underlined it invites the development of a distinctively interactivist account of life and mind. This account is provided, from its roots in the interactivist (...) biological constitution of life, through the evolution of the dual internal regulatory capacities expressed as intentionality and intelligence, to its expression in self-directed anticipative learning in persons and in science. (shrink)

I argue that beliefs about what appears possible are justified in much the same way as beliefs about what appears actual. I do so by chisholming, and then modalizing, the epistemic principle associated with phenomenal conservatism. The principle is tested against a number of examples, and it gives the intuitively correct results. I conclude by considering how it can be used to defend two controversial modal arguments, a Cartesian argument for dualism and an ontological argument for the existence of God.

All the major inter-theoretic relations of fundamental science are asymptotic ones, e.g. quantum theory as Planck's constant h 0, yielding (roughly) Newtonian mechanics. Thus asymptotics ultimately grounds claims about inter-theoretic explanation, reduction and emergence. This paper examines four recent, central claims by Batterman concerning asymptotics and reduction. While these claims are criticised, the discussion is used to develop an enriched, dynamically-based account of reduction and emergence, to show its capacity to illuminate the complex variety of inter-theory relationships in physics, and (...) to provide a principled resolution to such persistent philosophical problems as multiple realisability and the nature of the special sciences. Introduction Exposition Examination I: Claims (1) and (2), asymptotic explanation and reference Examination II: Claim (3), reduction and singular asymptotics Examination III: Claim (4), emergence and multiple realisability Conclusion. (shrink)

It is now commonly accepted that N. Goodman's predicate "grue" presents the theory of confirmation of C. G. Hempel (and other such theories) with grave difficulties. The precise nature and status of these "difficulties" has, however, never been made clear. In this paper it is argued that it is very unlikely that "grue" raises any formal difficulties for Hempel and appearances to the contrary are examined, rejected and an explanation of their intuitive appeal offered. However "grue" is shown to raise (...) an informal, "over-arching" difficulty of great magnitude for all theories of confirmation, including Hempel's theory. (shrink)

It is no longer possible to claim that the biological characteristics of the future adult are already determined at conception. After all, a zygote may develop into a hydatidiform mole rather than into a human being. The development of an individual human person is determined by genetically and nongenetically coded molecules within the embryo, together with the influence of the maternal environment. Consequently, it is an error to regard the zygote's chromosomal (and other) DNA as sufficient to determine the uniqueness (...) of the future individual. (shrink)

This book seeks to examine the mutual interplay between existentialism and Christian belief as seen through the work of three existentialist thinkers who were also committed Christians - a Spaniard, a Russian, and a Frenchman. They are compared with each other and with leading non-religious existentialists. The major themes studied include reason, freedom, the self, belief, hope, love, suffering, and immortality.

C A Wringe; Pupils’ Rights, Journal of Philosophy of Education, Volume 7, Issue 1, 30 May 2006, Pages 103–115, https://doi.org/10.1111/j.1467-9752.1973.tb00475.

This essay outlines the moral dilemma of funding orphan drug research and development. To date, ethical aspects of priority setting for research funding have not been an issue of discussion in the bioethics debate. Conflicting moral obligations of beneficence and distributive justice appear to demand very different levels of funding for orphan drug research. The two types of orphan disease, rare diseases and tropical diseases, however, present very different ethical challenges to questions about allocation of research funds. The dilemma is (...) analysed considering utilitarian and rights based theories of justice and moral obligations of non-abandonment and a professional obligation to advance medical science. The limitations of standard economic evaluation tools and other priority setting tools used to inform health policy decision makers on research funding decisions are outlined. (shrink)

Part I of this trilogy, Historical and Scientific Setting, set out a general context for selecting a certain subclass of inter-theoretic relations as achieving appropriate explanatory and ontological unification – hence for properly being labelled reductive. Something of the complexity of these relations in real science was explored. The present article concentrates on the role which identity plays in structuring the reduction relation and so in achieving ontological and explanatory unification.

The question of churches resorting to the courts to influence public policy is one that concerns the appropriate role of the courts and the appropriate conduct of religious authorities. I agree with Skene and Parker that there is no principled legal reason to exclude such interventions out of hand; but my comments are principally addressed to the political and religious reasons for being rightly concerned about such activity. These advert both to the nature of the liberal democratic compromise and to (...) the nature and scope of religious authority. (shrink)

In this response to Jonny Anomaly’s ‘Is Obesity a Public Health Problem?’ I argue, contra the author that public health actually increases individuals’ abilities to choose actions that further their health goals, specifically in the case of obesity. The intractability of obesity as an individual medical problem combined with the health benefits of modest (5–10 per cent of body weight) weight loss suggest that public health measures helping people make small changes in eating habits improve population health. I argue that (...) such measures are available to public health via behavioral economic research and policy proposals from libertarian paternalists. I respond to author’s claim that obesity does not constitute a public health problem because: (i) it is not an epidemic and (ii) obesity reduction is not a public good. I argue that epidemic status is not required for classification as a public health problem, but that obesity does have the status of an epidemic. I also point out flaws in author’s reasoning about obesity, public health and social costs. I conclude by suggesting that public health, in partnership with stakeholders and other areas of government, is poised to help create conditions for modest weight loss and increased population health overall. (shrink)

Contrary to the Empiricist model of science, successful sufficiently fundamental theories not only fit and unify their data fields but also prescribe the general terms in which relevantly to describe observation; specify what is and is not observable; specify the conditions under which what is observable, is observable; specify the instrumental means and reliability by which what is measurable is measured; specify what is causally, statistically, and merely accidentally connected. Moreover, such theories typically require all or most of the entire (...) remainder of science to be properly applied in any given situation and theoreticians' models play a crucial role in such applications. (I call these respectively the internal and external globalnesses of theories.) A discussion of the consequences of these global features of theories for philosophy of science is offered in the context of specific examples and a structural model for science. (shrink)

It is a theorem of Prikry [7] that ifκcarries a uniformη-descendingly complete ultrafilter then the stationary reflection propertyfails. In this paper we will derive similar results, but here from properties of filters rather than ultrafilters.Throughoutκandηwill denote regular cardinals withη<κ, andIwill denote an ideal onκ, by which we mean a setI⊆P such that Iis closed under taking subsets and finite unions and αЄIfor eachα<κ, butκ∉I.Iis said to beμ-complete if it is closed under taking unions of size <μ,I* = {X⊆κ∣κ−XЄI} is the (...) filter dual toIand ifAЄI+ −I), thenI∣Ais the ideal onκgiven byI∣A= {X⊆κ∣X∩AЄI}. Ifh: A→κthenhis said to be unbounded modIif for eachα<κ,h−1 = {ξЄA∣h<α} ЄIand a least function forIifhis unbounded modIand wheneverg: A→κis a function, unbounded modI, then {ξЄA∣g{ξ) shrink)