Cet article propose une réflexion sur les activités de recherche à partir de laboratoires industriels et académiques et d’organisations « intermédiaires » (laboratoires communs ; spin offs etc.). Les observations faites ponctuellement depuis une vingtaine d’années dans des laboratoires de chimie et de biologie montrent qu’elles sont l’objet d’une compétition accrue au niveau mondial entre différentes institutions et entre individus. La première hypothèse de l’article est que cette concurrence exacerbée entre entreprises, entre laboratoires académiques, entre scientifiques conduit à des stratégies (...) ayant pour objectifs une diminution des temps réservés par les prescripteurs (« les temps officiels ») pour chaque acte de recherche et à une rationalisation du travail scientifique dans le but d’accélérer la mise sur les marchés de produits, qu’ils soient académiques ou industriels, et ainsi d’en diminuer les coûts. Pour rendre compte de cette évolution, l’organisation des temps de travail en « opérations de recherche » est comparée à celle qui semble devenir prédominante aujourd’hui, la « logique-projet ». La seconde hypothèse est que ces nouvelles normes contraignantes influencent « la disponibilité temporelle » des travailleurs de la recherche et obligent de ce fait à s’interroger sur la place des chercheurs dans le salariat. (shrink)

La recherche a connu au cours du XXe siècle un processus d’autonomisation vis-à-vis des deux activités auxquels elle a été longtemps intégrée : l’enseignement supérieur, d’une part, la conception et la fabrication de nouveaux produits ou services d’autre part. Mais, dans le même temps, les activités de recherche tendent à se diffuser dans toutes les sphères des activités humaines, à commencer par les activités productives. L’autonomisation d’un secteur de la recherche s’est ainsi produite dan..

Caroline New is an energetic activist who has interpolated critical realist ideas into the front-line of political activism. In this wide-ranging interview, she begins by reflecting on her life and how she became a realist and her account is illustrated with personal anecdotes recalling memories of well-known philosophers and activists from the time. She discusses how her position set her apart from other feminists and she examines the interacting threads of longstanding debates on the political left, as well as (...) longstanding debates within critical realist circles, such as the relative importance of quantitative methods in social research and the scope for agency as a source of intentional change. Finally she brings some of her ideas to bear on contemporary issues. This engaging interview notably provides some of the social context in which critical realism developed, while also pointing towards its future potential. (shrink)

Ce compte rendu a déjà paru dans Territoire en mouvement – Revue de géographie et aménagement [En ligne], 34 | 2017. Luc Gwiazdzinski, La ville 24 heures sur 24, Paris, Rhuthmos, 2016, 254 p. Cet ouvrage présente les nouvelles relations de la ville au temps, ou comment la ville évolue en fonction de notre nouvelle occupation du temps. C'est une approche complexe qui est présentée ici, au travers des visions et analyses de spécialistes de différents domaines, mais qui tous ont (...) un lien - Recensions. (shrink)

On the morning of the third day on Circe's island of Aeaea, Odysseus takes sword and spear in hand and leaves his demoralized and exhausted crew to seek out some sign of habitation. Eventually, from the height of a rocky point, he spies smoke rising in the distance. After debating with himself whether or not to investigate immediately, he determines first to return to his ships, in order to see about his comrades' dinner. Returning to the beach, he encounters an (...) enormous stag, which he takes to have been sent by a god who pitied him and which he kills, binds with a makeshift rope of brushwood and willow branches, and drags back to the camp. (shrink)

This article assesses the usefulness of Thomas Risse, Stephen Ropp and Kathryn Sikkink's spiral model as an explanation of the changes in the Chinese government's human rights practices from the time of the 'anti-rightist' campaign in 1957-1958 to the end of 2003. It is concluded that the spiral model has provided a valid explanation for many of the changes in the Chinese government's human rights practices, and its responses to its internal and external critics, over this time period. Many of (...) the responses of the transnational human rights network and the Chinese government by the end of this period indicate that the latter had progressed to phase three of the model. It is also concluded that the spiral model only conceptualises part of the constitutive relationship between the target state and international human rights norms - the influence of these norms on the identities, interests and behaviours of a target state. It does not conceptualise the influence of a target state on international human rights norms or the transnational human rights network. Therefore, the spiral model cannot explain why the Chinese government has had such a significant influence over the enforcement mechanisms of these norms. (shrink)

Als wahrscheinlich älteste vollständige Überlieferung des Buddhismus reflektiert der Pali-Kanon in literarisch-narrativer Form die Auseinandersetzung mit religiös,Anderen' aus emischer Perspektive. Die Suttas berichten nicht nur, wie der Buddha Mitglieder seines Ordens belehrt, sondern auch, wie er Vertretern anderer religiöser Gruppierungen begegnet und mit ihnen diskutiert haben soll. Caroline Widmer untersucht, inwiefern in diesen Begegnungen religiöse Abgrenzung im Sinne eines Otherings literarisch dargestellt wird, und behandelt diese religionswissenschaftliche Fragestellung im Bereich des Buddhismus erstmals durch eine literaturwissenschaftlich angelegte Analyse der narrativen (...) Gestaltung der Pali-Suttas. Die Texte spiegeln jedoch nicht wie oftmals angenommen in erster Linie Toleranz oder Offenheit gegenüber anderen religiösen Ansichten wider; vielmehr sind durch einen hohen Grad an Selbstdarstellung und einem exklusiven Anspruch auf Wahrheitsbesitz geprägt. Erzählerisch wird diese Spannung so aufgelöst, dass der,Andere' das,Eigene' annimmt und dadurch seine,Andersheit' verliert. Die Untersuchung eröffnet einen neuen Zugang zu religionsgeschichtlichen Quellen, erlaubt detaillierte Einblicke in diesen systemspezifischen Prozess des Selfings und erläutert seine Funktion innerhalb der buddhistischen Überlieferung. (shrink)

_A provocative reassessment of the concept of an American golden age of European-born reason and intellectual curiosity in the years following the Revolutionary War_ The accepted myth of the “American Enlightenment” suggests that the rejection of monarchy and establishment of a new republic in the United States in the eighteenth century was the realization of utopian philosophies born in the intellectual salons of Europe and radiating outward to the New World. In this revelatory work, Stanford historian Caroline Winterer argues (...) that a national mythology of a unitary, patriotic era of enlightenment in America was created during the Cold War to act as a shield against the threat of totalitarianism, and that Americans followed many paths toward political, religious, scientific, and artistic enlightenment in the 1700s that were influenced by European models in more complex ways than commonly thought. Winterer’s book strips away our modern inventions of the American national past, exploring which of our ideas and ideals are truly rooted in the eighteenth century and which are inventions and mystifications of more recent times. (shrink)

Up Against Foucault offers both a feminist critique of Foucauldian theories as well as an attempt to reconcile these seemingly irreconcilable perspectives. Feminists are often "up against Foucault" because he questions key conclusions in feminism regarding the nature of gender relations, and men's possession of power. This book, however, fills the gap in literature about Foucault by showing how his theories of sexuality and power relations are often applicable to the everyday realities of women's lives. Drawing upon their diverse backgrounds (...) in social theory and philosophy, the contributors discuss the ways in which Foucault provokes feminists into questioning their grasp of power relations, and examines the implications of his decision to overlook categories of gender in his discussion of sexuality and power relations. They also show that in spite of his lack of interest in gender, Foucault's ways of understanding the control of women and female sexuality ultimately have much to offer feminism. (shrink)

Bisher ist die Rolle von Ethikkomitees und Ethikberatenden als Ressource im Umgang mit der Covid-19-Pandemie ungeklärt. Im vorliegenden Beitrag wird diskutiert, worin spezifische Herausforderungen bei der ethischen Bewertung von Fragen an Ethikkomitees im Pandemiekontext bestehen und welche möglichen Aufgaben für Ethikberatende identifiziert werden könnten. Dabei wird die Ansicht vertreten, dass es für die kompetente, professionelle Bearbeitung dieser Fragen hilfreich wäre, das theoretische Grundverständnis der Ethikberatung für den Pandemiekontext zu reflektieren, die begründungstheoretischen, normativen Argumente aktueller Publikationen und Stellungnahmen der Fachgesellschaften zu (...) diskutieren und Weiterbildungspotenzial sowie Kompetenzgrenzen zu identifizieren. Für werden zur Kompetenzerweiterung Public-Health-Ethik und Ethik der Menschenrechte vorgeschlagen, psychische Entlastung bei ‚moralischem Stress‘ wird als ethisch-psychologischer Kooperationsbereich diskutiert und die explizite Abgrenzung vom juristischen Bereich wird empfohlen. Ethikberatung könnte den konstruktiven Umgang mit ethischen Fragen im Pandemiekontext fördern, die Qualität von Entscheidungs- und Bewertungsprozessen verbessern und in der Versorgungspraxis pragmatische, konkrete Hilfestellung anbieten. (shrink)

This paper builds on existing research investigating CSR and ethical consumption within luxury contexts, and makes several contributions to the literature. First, it addresses existing knowledge gaps by exploring the ways in which consumers perform ethical luxury purchases of fine jewellery through interpretive research. Second, the paper is the first to examine such issues of consumer ethics by extending the application of theories of practice to a luxury product context, and by building on Magaudda’s :15–36, 2011) circuit of practice framework. (...) This is significant in that, to date, consumer research using practice theories has focused mainly on routine and habitual practices. Our findings and discussion provide an analysis of intentional and less intentional ethical consumer performances within the interconnected nexus of activities of consumers’ fine jewellery consumption practice, where meanings, understandings and intelligibility of social phenomena are worked through the various activities that shape such a practice. Finally, the paper concludes with significant managerial and policy-related implications, as our extended circuit of practice analysis conveys that if ethics and sustainability dimensions are to be embedded in fine jewellery consumption practice, they must first be made an intrinsic part of the nexus of the social and material environment of trading and consumption places. (shrink)

Engineers encounter difficult ethical problems in their practice and in research. In many ways, these problems are like design problems: they are complex, often ill-defined; resolving them involves an iterative process of analysis and synthesis; and there can be more than one acceptable solution. This book offers a real-world, problem-centered approach to engineering ethics, using a rich collection of open-ended scenarios and case studies to develop skill in recognizing and addressing ethical issues.

In this paper I outline an “agent-centered” approach to learning ethics. The approach is “agent-centered” in that its central aim is to prepare students toact wisely and responsibly when faced with moral problems. The methods characteristic of this approach are suitable for integrating material on professional and research ethics into technical courses, as well as for free-standing ethics courses. The analogy I draw between ethical problems and design problems clarifies the character of ethical problems as they are experienced by those (...) who must respond to them. It exposes the mistake, common in ethics teaching, of misrepresenting moral problems as multiple-choice problems, especially in the form of ‘dilemmas’, that is, a forced choice between two unacceptable alternatives. Furthermore, I clarify the importance for responsible practice of recognizing any ambiguity in the problem situation. (shrink)

This paper examines the way in which causal relations are understood in the dominant model in contemporary medicine. It argues that the causal relation is not definable in terms of the condition relation, but that in general for conditions of an occurrence to be among its causes they must answer instrumental interests in a certain way, and there are further criteria for distinguishing 'the' cause of a disease (i.e., its etiological agent) from other causal factors, which are based upon instrumental (...) interests peculiar to medicine. It also argues that diseases are complex processes of which both clinical and underlying patho-physiological manifestations are proper parts (as contrasted with effects). (shrink)

The current study provides data about the immediate risk perceptions and psychological effects of the COVID-19 pandemic among Italian participants. A sample of 1034 volunteers answered a web-based survey which aimed to investigate the many facets of risk perceptions connected to COVID-19 (health, work, economy, social and psychological), and risk-related variables such as knowledge, news seeking, perceived control, efficacy of containment measures, and affective states. Socio-demographic characteristics were also collected. Results showed that although levels of general concern are relatively high (...) among Italians, risk perceptions are highest with regards to the economy and work, and lowest concerning health. Cognitive and affective risk-related variables affected the several risk perception domains differently. COVID-19 knowledge did not affect any risk perception while the perceived control decreased health risk likelihood. The other risk-related variables amplified risk perceptions: News seeking increased work-economy risk; efficacy of containment measures increased all perceived risks; negative affective states of fear, anger and sadness increased health and psycho-social risks; anxiety increased only health risk, and uncertainty increased work-economy and psycho-social risk perceptions. Finally, positive affective states increased health risk perception. Socio-psychological implications are discussed. (shrink)

A cause is proportional to its effect when, roughly speaking, it is at the right level of detail. There is a lively debate about whether proportionality is a necessary condition for causation. One of the main arguments against a proportionality constraint on causation is that many ordinary and seemingly perfectly acceptable causal claims cite causes that are not proportional to their effects. In this paper, I suggest that proponents of a proportionality constraint can respond to this objection by developing an (...) idea that is present in Yablo’s early work on proportionality, but which has strangely been ignored by both Yablo and others in the subsequent debate. My suggestion is that proportionality—and, indeed, causation itself—is relative to a domain of events. At the metaphysical level, this means that the causal relation has an extra relatum—namely, a domain of events. At the level of language, it introduces a new way in which causal claims are context-sensitive: what is expressed by a causal claim depends on the contextually relevant domain of events. As I argue, this suggestion allows us to accommodate the truth of ordinary causal claims while extending the explanatory benefits of a proportionality constraint. (shrink)

Izates, Helena, and Monobazos of Adiabene: A Study on Literary Traditions and History. By Michal Marciak. Philippika, vol. 66. Wiesbaden: Harrassowitz Verlag, 2014. Pp. 316, illus. €62.

Parkinson´s disease (PD) is a neurodegenerative disorder characterized by motor symptoms following dopaminergic depletion in the substantia nigra. Besides motor impairments however, several non-motor detriments can have the potential to considerably impact subjectively perceived quality of life in patients. Particularly emotion recognition of facial expressions has been shown to be affected in PD, and especially the perception of negative emotions like fear, anger or disgust is impaired. While emotion processing generally refers to automatic implicit as well as conscious explicit processing, (...) the focus of most previous studies in PD was on explicit recognition of emotions only, while largely ignoring implicit processing deficits. Deep brain stimulation of the subthalamic nucleus (STN-DBS) is widely accepted as therapeutic measure in the treatment of PD and has been shown to advantageously influence motor problems. Among various concomitant non-motor effects of STN-DBS, modulation of facial emotion recognition under subthalamic stimulation has been investigated in previous studies with rather heterogeneous results. While there seems to be consensus regarding the processing of disgust which significantly deteriorates under STN stimulation, findings concerning emotions like fear or happiness report heterogeneous data and seem to depend on various experimental settings and measurements. In the present review, we summarized previous investigations focusing on STN-DBS influence on recognition of facial emotional expressions in patients suffering from PD. In a first step, we provide a synopsis of disturbances and problems in facial emotion processing observed in patients with PD. Secondly, we present findings of STN-DBS influence on facial emotion recognition and especially highlight different impacts of stimulation on implicit and explicit emotional processing. (shrink)

We review different conceptions of the set-theoretic multiverse and evaluate their features and strengths. In Sect. 1, we set the stage by briefly discussing the opposition between the ‘universe view’ and the ‘multiverse view’. Furthermore, we propose to classify multiverse conceptions in terms of their adherence to some form of mathematical realism. In Sect. 2, we use this classification to review four major conceptions. Finally, in Sect. 3, we focus on the distinction between actualism and potentialism with regard to the (...) universe of sets, then we discuss the Zermelian view, featuring a ‘vertical’ multiverse, and give special attention to this multiverse conception in light of the hyperuniverse programme introduced in Arrigoni and Friedman (2013). We argue that the distinctive feature of the multiverse conception chosen for the hyperuniverse programme is its utility for finding new candidates for axioms of set theory. (shrink)

In vertebrates, single cell analyses of replication timing patterns brought to light a very well controlled program suggesting a tight regulation on initiation sites. Mapping of replication origins with different methods has revealed discrete preferential sites, enriched in promoters and potential G‐quadruplex motifs, which can aggregate into initiation zones spanning several tens of kilobases (kb). Another characteristic of replication origins is a nucleosome‐free region (NFR). A modified yeast strain containing a humanized origin recognition complex (ORC) fires new origins at NFRs (...) revealing their regulatory role. In cooperation with NFRs, the histone variant H2A.Z facilitates ORC loading through di‐methylation of lysine 20 of histone H4. Recent studies using genome editing methods show that efficient initiation sites associated with transcriptional activity can synergize over several tens of kb by establishing physical contacts and lead to the formation of early domains of DNA replication demonstrating a co‐regulation between replication initiation and transcription. (shrink)

Cher, T-Pain, Saez, Châton, Booba, Benjamin Biolay, Bon Iver, Yung Beef, Lady Gaga, Neil Young ou encore PNL, tous ces artistes ont en commun l’usage de l’Auto-Tune. Ce dernier désigne un logiciel permettant d’ajuster, de corriger la voix à la suite d’un enregistrement ou durant une performance. Si initialement, l’Auto-Tune permet de chanter juste, cela est également utilisé pour produire des modulations sonores donnant un caractère artificiel, robotique, non linéaire à la voix humaine. Le premier titre avec une présence marquée (...) de l’Auto-Tune est « Believe » de Cher sorti en 1998 qui connaît un succès retentissant. Depuis, si quelques artistes – à l’image de Jay-Z et son titre D.O.A. pour « Death of Auto-Tune » (2009) – dénoncent cette pratique, l’Auto-Tune a conquis l’industrie musicale et serait utilisé dans la quasi-totalité des productions (Reynolds, 2019), toutes les esthétiques confondues. Malgré cette diffusion, encore peu de recherches académiques abordent cette question. Quels sont les enjeux liés à l’Auto-Tune? (shrink)

Habermas anuncia em sua obra Pensamento Pós-Metafísico o fim da metafísica enquanto pensamento totalizador e auto-referente que pretende um acesso privilegiado à verdade. A desvalorizaçáo deste modo de pensar culmina na passagem para o que ele denomina de pensamento pós-metafísico, fazendo-se necessário um redimensionamento do papel da filosofia, visto que um novo cenário de pensamento se instaura. O presente artigo pretende problematizar, à luz da filosofia de Heidegger, os pressupostos habermasianos que fundamentam a sua constataçáo do fim da metafísica. Neste (...) sentido, procura indicar que a constataçáo do império da técnica na contemporaneidade torna o anuncio da instauraçáo de um pensar pós-metafísico algo de difícil sustentaçáo. Palavras-chave: Habermas; Heidegger; Metafísica; Pensamento pós-metafísico; Técnica. (shrink)

In Canada, all institutions that conduct publicly funded, animal-based research are expected to comply with the standards of the Canadian Council on Animal Care (CCAC). The CCAC promotes the use of animal alternatives, and uses the “3Rs” principles of Replacement, Reduction, and Refinement as a guiding ethical framework. To ensure these standards are strictly enforced, internal ethics committees at each institution are tasked with creating “Animal Use Protocol” (AUP) forms to be filled out by researchers and evaluated by the committees. (...) In this paper, we assess AUP forms from Canada’s top research universities to identify the extent to which they conform to, or advance, the 3Rs framework. Our results show various deficiencies that call into question the quality of information elicited by these forms. To remedy this, we recommend that the CCAC assume responsibility for creating a standardized 3Rs section to be used on all AUP forms. In addition, proposal forms and experimental results for all research at CCAC-certified institutions should be digitized and uploaded into a national database. We argue that this would offer higher quality information for researchers at the experimental design stage, while strengthening the CCAC’s mandate to be accountable to the Canadian public. (shrink)