Recent advances in wireless data transmission technology have the potential to revolutionize clinical neuroscience. Today sensing-capable electrical stimulators, known as “bidirectional devices”, are used to acquire chronic brain activity from humans in natural environments. However, with wireless transmission come potential failures in data transmission, and not all available devices correctly account for missing data or provide precise timing for when data losses occur. Our inability to precisely reconstruct time-domain neural signals makes it difficult to apply subsequent neural signal processing techniques (...) and analyses. Here, our goal was to accurately reconstruct time-domain neural signals impacted by data loss during wireless transmission. Towards this end, we developed a method termed Periodic Estimation of Lost Packets. PELP leverages the highly periodic nature of stimulation artifacts to precisely determine when data losses occur. Using simulated stimulation waveforms added to human EEG data, we show that PELP is robust to a range of stimulation waveforms and noise characteristics. Then, we applied PELP to local field potential recordings collected using an implantable, bidirectional DBS platform operating at various telemetry bandwidths. By effectively accounting for the timing of missing data, PELP enables the analysis of neural time series data collected via wireless transmission—a prerequisite for better understanding the brain-behavior relationships underlying neurological and psychiatric disorders. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

Grandiose narcissistic traits refer to exploitative and arrogant attitudes, while vulnerable narcissistic traits entail hypersensitivity to judgment and low self-esteem. Little is known about how individuals with narcissistic traits can improve their attitudes toward themselves and others. The current research puts self- and other compassion forward as possible targets to alleviate some of destructive patterns of narcissism. Generally, self-compassion has previously been associated with beneficial effects on psychological wellbeing, while other compassion is advantageous for interpersonal relationships. This study explored the (...) relationship between narcissistic traits and the efficacy of experimental compassion inductions. Student and community participants completed grandiose and vulnerable narcissistic trait, SC and OC state questionnaires, and either an SC or OC induction. It was expected that individuals with higher narcissistic traits would benefit from the inductions and show higher SC after but would have greater difficulty showing meaningful increases in OC. The results indicated that individual differences in grandiose and vulnerable narcissistic traits are related to the magnitude of improvements following the inductions: the theorized lack of SC in individuals with vulnerable oversensitivity to judgment traits seems possible to be counteracted through different types of compassion exercises. Moreover, higher grandiose exploitativeness–entitlement and global vulnerable narcissistic traits related to less increases than others. However, directly inducing OC in individuals with these traits was linked to greater OC improvements than improvements after inducing SC. Overall, the present findings suggest that self-compassionate behavior can be improved in individuals with high oversensitivity and that other compassionate behavior could potentially be increased if, specifically, other compassion exercises are utilized when higher levels of certain narcissistic traits are present. (shrink)

In editing Plato's Sophist for the new OCT vol. I, ed. E. A. Duke, W. F. Hicken, W. S. M. Nicoll, D. B. Robinson, and J. C. G. Strachan , there was less chance of giving novel information about W = Vind. Supp. Gr. 7 for this dialogue than for others in the volume, since Apelt's edition of 1897 was used by Burnet in 1900 and was based on Apelt's own collation of W. The result was better than the somewhat (...) confused information printed by Burnet, even in his 1905 reprint, for W for the other dialogues in vol. I. But in the Sophist as elsewhere in vol. I collations largely due to Dr W. S. M. Nicoll added new facts about all of BDTWP and their correctors, and the search for testimonia largely carried out by Dr E. A. Duke added new facts in that area. A reviewer counts 66 changes in our text of the Sophist, which may perhaps be a slight over-estimate. Classification of changes as substantive or as falling into different groups is sometimes difficult, but I think plausible figures are as follows. We have in 25 places made a different choice of readings from the primary mss. and testimonia. We have printed conjectures where Burnet kept a ms. reading in 17 places, but conversely we have reverted to a ms. reading where Burnet had a conjecture in 8 places. We have printed alternative conjectures to conjectures adopted by Burnet in 6 places. So we have actually departed from the primary sources on at most 9 more occasions overall than Burnet. What must be noted is that Burnet had already printed conjectures on something like 87 occasions , so our percentage addition to Burnet's departures from the primary sources is modest. Moreover Burnet printed about 25 readings from testimonia; we have followed him in 20 or so of these cases, and this in turn implies that the primary mss. are in error at these further 20 places. It needs to be underlined that though Burnet undoubtedly deserved to be regarded as a safe and cautious editor, nevertheless he departed from the primary mss. on average about twice per Stephanus page in this dialogue. Sometimes, of course, testimonia showed him right to do this, but testimonia cover only a quite small part of this dialogue. Otherwise Burnet accepted almost 90 conjectures. For the Politicus the figures are fairly similar; Burnet accepted 22 Byzantine conjectures and 35–40 more modern ones. The new OCT there adds 15 or so more conjectures. (shrink)

This anthology brings together readings mainly from contemporary philosophers, but also from writers of the past two centuries, on the philosophy of mind. Some of the main questions addressed are: is a human being really a mind in relation to a body; if so, what exactly is this mind and how it is related to the body; and are there any grounds for supposing that the mind survives the disintegration of the body?

This collection highlights such issues as how the nature of time is relevant to the question of whether God is temporal and how God's other attributes are ...

Remarks such as ‘I am in pain’ and ‘I think that it’s raining’ are puzzling, since they seem to literally describe oneself as being in pain or having a particular thought, but their conditions of use tend to coincide with unequivocal expressions of pain or of that thought. This led Wittgenstein, among others, to treat such remarks as expressing, rather than as reporting, one’s mental states. Though such expressivism is widely recognized as untenable, Bar-On has recently advanced a neo-expressivist view, (...) on which such remarks exhibit characteristics of both expressions of mental states and reports of those states. I argue against any attempt to see such remarks as both reporting and expressing the same mental states, and that a correct account rests on distinguishing the truth conditions of such remarks from their conditions of use. (shrink)

This article highlights the mathematical structure of Henri Bergson’s method. While Bergson has been historically interpreted as an anti-scientific and irrationalist philosopher, he modeled his philosophical methodology on the infinitesimal calculus developed by Leibniz and Newton in the seventeenth century. His philosophy, then, rests on the science of number, at least from a methodological standpoint. By looking at how he conscripted key mathematical concepts into his philosophy, this article invites us to re-imagine Bergson’s place in the history of Western philosophy.

The human enhancement debate has over the last few decades been concerned with ethical issues in methods for improving the physical, cognitive, or emotive states of individual people, and of the human species as a whole. Arguments in favour of enhancement defend it as a paradigm of rationality, presenting it as a clear-eyed, logical defence of what we stand to gain from transcending the typical limits of our species. If these arguments are correct, it appears that adults should in principle (...) be able to make rational and informed decisions about enhancing themselves. In this paper, however, we suggest that a rational and informed choice to enhance oneself may in some cases be impossible. Drawing on L. A. Paul’s work on ‘transformative experience’, we argue that some enhancements—such as certain moral or cognitive modifications—may give rise to unbridgeable epistemic gaps in key domains. Importantly, such gaps could prove to be not merely contingently unbridgeable due to a lack of information at a given moment, but radically unbridgeable, making someone in a non-enhanced state inherently unable to conceive of what it would be like to be enhanced in a particular way. Where this experience is key to understanding what values are being pursued by the enhancement itself, it may prove impossible for a person to be sufficiently informed, and to make a rational decision about whether or not to enhance herself. This poses a challenge for human enhancement proponents in general, and for transhumanists in particular. (shrink)

There is an awakening of interest in links between geography and moral philosophy, or ethics. This paper reviews a range of issues where common ground might be found on this new disciplinary interface. These issues include the historical geography of moralities, the notion of moral geographies, inclusion and exclusion in the context of the bounding of spaces, and the moral significance of distance and proximity, as well as the more familiar concern with social justice. Environmental ethics provides a link with (...) the physical side of the subject. Some suggestions are made as to the possible contribution of geography to the understanding of moral issues. (shrink)

A philosophy might take its general inspiration from (1) commonsense; (2) careful observation; (3) philosophical argumentation; (4) the sciences; (5) "higher" sources of illumination. It is argued in this paper that it is bedrock commonsense, and the sciences, which are the most reliable foundations for a philosophy. This result is applied to the discussion and defense of a materialist theory of the mind.

Professor Grünbaum's much-discussed refutation of Zeno's metrical paradox turns out to be ad hoc upon close examination of the relevant portion of measure theory. Although the modern theory of measure is able to defuse Zeno's reasoning, it is not capable of refuting Zeno in the sense of showing his error. I explain why the paradox is not refutable and argue that it is consequently more than a mere sophism.

Although prediction is one of the key tasks of intelligent brains, it often proves impossible in an unpredictably changing world. Hence, brains often decide what happened retrospectively. This framework of postdiction, the opposite of prediction, stands as an alternative or complimentary framework to prediction. I further show how motor-sensory recalibration demonstrates delay compensation at the perceptual level.

Although Ramachandra Guha has demonstrated the importance of cross-cultural dialogue on environmental issues and has much to tell us about the problems of wildemess preservation in the Third World, I argue that Guha is partly wrong in claiming that deep ecology equates environmental protection with wilderness protection and simply wrong in calling wilderness protection untenable or incorrect as aglobal strategy for environmental protection. Moreover, I argue that the deep ecology distinction between anthropocentrism and biocentrism is useful in dealing with the (...) two major problems which Guha identifies as undermining the health of the planetoverconsumption and militarism. Although it is true that preservation of wildemess will not be successful unless human social dynamics are taken into consideration, nevertheless, a biocentrism which integrates critical social theory can provide the basis for an ethic that undercuts the environmental degradation from overconsumption and militarism more effectively than a human-centered system. (shrink)

This long-awaited new edition contains eight of the dialogues of Plato, and is the first in a new five-volume complete edition of his works in the OCT series.

Richard Wolin questions the connection between the philosophy and politics of Paul Ricoeur to make three charges: 1) Ricoeur's version of hermeneutics slides into a relativism of incommensurable perspectives; 2) Ricoeur's "covert agenda" in his recent work, Memory, History, Forgetting is to come to terms with the regrettable choices he made in his youth; 3) Ricoeur left us a written record of his pro-Vichy sympathies that raise questions about the political implications of hermeneutics. Each claim is, however, far from true. (...) Ricoeur's hermeneutics is particularly sensitive to the charge of relativistic incommensurability and avoids it assiduously; his philosophical motivations in writing Memory, History, Forgetting are well known and are more important with respect to the work's merit than his personal motivations; and his early political writings need to be read in light of a broader, life-long attempt to find a balance between the universal and particular in hermeneutics, ethics, and politics. (shrink)

The paper argues that Paul Ricoeur's The Philosophy of the Will retained a certain fidelity to phenomenology's early emphasis on subjectivity. When Ricoeur turned to the philosophy of language, he found a way to retain a certain emphasis on subjectivity and individuality that would make his work distinctive among other approaches to the philosophy of language. Hence, the title, Preserving the Eidetic Moment, intends to characterize Ricoeur's distinctive contribution to philosophy. The paper goes on to show how Ricoeur's approach can (...) contribute to Critical Theory, particularly in relationship to its theory of interlocution. (shrink)

This study examines the relationship between cognitive moral development (CMD), productivity features of information technology (IT) and unethical behavior or misconduct. Using an experimental design that randomly assigns subjects to one of four unique technology conditions, we assess the relationship between a subjects' predominant level of CMD and ethical misconduct on IT-oriented work tasks. Our results show that both higher levels of CMD and increased levels of IT productivity features at one's disposal have a significant role to play in explaining (...) observed behavior in our sample. We find that CMD as measured by the Defining Issues Test's P-score is negatively related to task misconduct. Conversely, IT productivity features such as copy-and-paste are positively related to task misconduct. In addition, the CMD—misconduct relationship is significantly diminished by the introduction of IT productivity features. Lastly, a series of hazard analyses are conducted to explore the boundaries of our principal findings. These results demonstrate the significant role of technology in enabling negative behavior and the relative inability of subjects' use of principled moral reasoning to overcome it. Implications of these findings for academics and business managers are offered, as well as recommendations for mitigating misconduct in both academic and workplace environments. (shrink)

This text addresses the profound human questions of love and work. Beginning with a historical introduction, the author progresses through adaptive problems that humans face, and concludes by showing how evolutionary psychology encompasses all branches of psychology.

Sat, or truth, is one of the dominant motifs in Margaret Chatterjee’s book, Gandhi’s Religious Thought. For Gandhi, satyagraha, or the search for truth, was one of the driving forces in his life. But the satyagrahi, or the seeker of truth, cannot do this in a vacuum. A series of vows to such virtues as non-violence and fearlessness provide a matrix akin to existential commitment, and guides the marga or path towards this goal.

Right now, you are undergoing the conscious experience of reading this text, combined with a shifting background of sensory, emotional, and cognitive coloring. The conscious experience of the reading, together with the accompanying background feel of sensation, emotion, and thought, make up how things subjectively seem to you, how things appear, as best you can tell, from your own unique point of view. Consciousness is at once acutely familiar-it makes up the experienced moments of your waking (and perhaps your dreaming) (...) life. But consciousness also raises deep and interesting philosophical questions, questions about how any mere physical subject could produce such a wonder, and questions about how there could be a seemingly private and isolated spot of personal subjectivity in an objective, impersonal world. Perhaps the challenge of developing a satisfying theoretical understanding of consciousness is beyond us-we've reached the limits of what we can comprehend. Or maybe today's shortcomings are only temporary barriers to an illuminating theory of consciousness, one properly embedding it in our scientific worldview. And possibly we already have the resources for a satisfactory theory from the way we think about things in commonsense terms. This reader provides an entry point for considering these and related theoretical questions surrounding consciousness. This introductory section begins with a brief background survey of contemporary debates on consciousness. It then provides a characterization of the notion of consciousness at issue, and considers why consciousness understood this way might be theoretically problematic. It follows with a survey of some of the major theoretical positions on consciousness, and it closes with a synopsis of the sections of the book. (shrink)

Iconicity refers to a resemblance between word form and meaning. Previous work has shown that iconic words are learned earlier and processed faster. Here, we examined whether iconic words are recognized better on a recognition memory task. We also manipulated the level at which items were encoded—with a focus on either their meaning or their form—in order to gain insight into the mechanism by which iconicity would affect memory. In comparison with non‐iconic words, iconic words were associated with a higher (...) false alarm rate, a lower d’ score, and a lower response criterion in Experiment 1. We did not observe any interaction between iconicity and encoding condition. To test the generalizability of these findings, we examined effects of iconicity in a recognition memory megastudy across 3880 items. After controlling for a variety of lexical and semantic variables, iconicity was predictive of more hits and false alarms, and a lower response criterion in this dataset. In Experiment 2, we examined whether these effects were due to increased feelings of familiarity for iconic items by including a familiar versus recollect decision. This experiment replicated the overall results of Experiment 1 and found that participants were more likely to categorize words that they had seen before as familiar (vs. recollected) if they were iconic. Together, these results demonstrate that iconicity has an effect on memory. We discuss implications for theories of iconicity. (shrink)

Because metacognition consists in our having mental access to our cognitive states and mental states are conscious only when we are conscious of them in some suitable way, metacognition and consciousness shed important theoretical light on one another. Thus, our having metacognitive access to information carried by states that are not conscious helps con?rm the hypothesis that a mental state.

A prominent view on personal identity over time, Jeff McMahan’s ‘Embodied Mind Account’ (2002) holds that we cease to exist only once our brains can no longer sustain the basic capacity to uphold consciousness. One of the many implications of this view on identity persistence is that we continue to exist throughout even the most severe cases of dementia, until our consciousness irreversibly shuts down. In this paper, I argue that, while the most convincing of prominent accounts of personal identity (...) over time, McMahan’s account faces serious challenges in explanatory power of dementias and related neurodegenerative conditions. Particularly, this becomes visible in the face of emerging methods for neural tissue regeneration, and the possibility of ‘re-emerging patients’. I argue that medical professionals’ neglecting qualitative aspects of identity risks resulting in grave misunderstandings in decision-making processes, and ethically objectionable outcomes in future practices. Finally, I propose revisions which could potentially salvage the great benefits that Embodied Mind Theory still can bring to the field of dementia care in terms of understanding life, death, and identity across the lifespan. (shrink)

Theories of what it is for a mental state to be conscious must answer two questions. We must say how we're conscious of our conscious mental states. And we must explain why we seem to be conscious of them in a way that's immediate. Thomas Natsoulas distinguishes three strategies for explaining what it is for mental states to be conscious. I show that the differences among those strategies are due to the divergent answers they give to the foregoing questions. Natsoulas (...) finds most promising the strategy that amounts to the higher-order-thought hypothesis that I've defended elsewhere. But he raises a difficulty for it, which he thinks probably can be met only by modifying that strategy. I argue that this is unnecessary. The difficulty is a special case of a general question, the answer to which is independent of any issues about consciousness. So it's no part of a theory of consciousness to address the problem, much less solve it. Moreover, the difficulty seems to have intuitive force only given the picture that underlies the other two explanatory strategies, which both Natsoulas and I reject. (shrink)

red and round. According to common sense, the red, round thing we see is the tomato itself. When we have a hallucinatory vision of a tomato, however, there may be present to us no red and round phys- ical object. Still, we use the words 'red' and 'round' to describe that situation as well, this time applying them to the visual experience itself. We say that we have a red, round visual image, or a visual experience of a red disk, (...) or some such. Because we see physical objects far more often than we hallucinate, we apply terms for color and shape to physical objects far more often than to visual experiences. Moreover, different theories of perception explain in different ways the applications such terms have to physical objects and to visual experiences. But whatever their frequency and explanation, it seems clear that both sorts of application occur. (shrink)