Electroencephalography provides a non-invasive means to advancing our understanding of the development and function of the brain. However, the majority of the world’s population residing in low and middle income countries has historically been limited from contributing to, and thereby benefiting from, such neurophysiological research, due to lack of scalable validated methods of EEG data collection. In this study, we establish a standard operating protocol to collect approximately 3 min each of eyes-open and eyes-closed resting-state EEG data using a low-cost (...) portable EEG device in rural households through formative work in the community. We then evaluate the acceptability of these EEG assessments to young children and feasibility of administering them through non-specialist workers. Finally, we describe properties of the EEG recordings obtained using this novel approach to EEG data collection. The formative phase was conducted with 9 families which informed protocols for consenting, child engagement strategies and data collection. The protocol was then implemented on 1265 families. 977 children and 1199 adults provided resting-state data for this study. 259 children refused to wear the EEG cap or removed it, and 58 children refused the eyes-closed recording session. Hardware or software issues were experienced during 30 and 25 recordings in eyes-open and eyes-closed conditions respectively. Disturbances during the recording sessions were rare and included participants moving their heads, touching the EEG headset with their hands, opening their eyes within the eyes-closed recording session, and presence of loud sounds in the testing environment. Similar to findings in laboratory-based studies from high-income settings, the percentage of recordings which showed an alpha peak was higher in eyes-closed than eyes-open condition, with the peak occurring most frequently in electrodes at O1 and O2 positions, and the mean frequency of the alpha peak was found to be lower in children as compared to adults. We observed a deterioration in the EEG signal with prolonged device usage. This study demonstrates the acceptability, feasibility and utility of conducting EEG research at scale in a rural low-resource community, while highlighting its potential limitations, and offers the impetus needed to further refine the methods and devices and validate such scalable methods to overcome existing research inequity. (shrink)

Hastings Center Report, Volume 52, Issue 3, Page 37-48, May–June 2022.

In Unseen City: The Psychic Lives of the Urban Poor, Ankhi Mukherjee offers a magisterial work of literary and cultural criticism which examines the relationship between global cities, poverty, and psychoanalysis. Spanning three continents, this hugely ambitious book reads fictional representations of poverty with each city's psychoanalytic and psychiatric culture, particularly as that culture is fostered by state policies toward the welfare needs of impoverished populations. It explores the causal relationship between precarity and mental health through clinical case studies, (...) the product of extensive collaborations and knowledge-sharing with community psychotherapeutic initiatives in six global cities. These are layered with twentieth- and twenty-first-century works of world literature that explore issues of identity, illness, and death at the intersections of class, race, globalisation, and migrancy. In Unseen City, Mukherjee argues that a humanistic and imaginative engagement with the psychic lives of the dispossessed is key to an adapted psychoanalysis for the poor, and that seeking equity of the unconscious is key to poverty alleviation. (shrink)

Mrs. Smith's eyes filled with tears as she said, “I feel like I've done something wrong. Are they punishing me because I've been refusing therapy and won't go to a nursing home?” She acknowledged that she hadn't always listened to her doctors but said that she knew better now and wanted to go home and see if she could make it work. Many staff members at our rehabilitation hospital had explained their safety concerns to her, and some had enlisted her (...) adult daughter, with whom she lived, to convince her too. The rehabilitation team had called on the ethics consultation service, of which I am a part, to help figure out whether Mrs. Smith had the capacity to make an informed refusal of discharge recommendations. (shrink)

Debates in the philosophy of science typically take place around issues such as realism and theory change. Recently, the debate has been reformulated to bring in the role of experiments in the context of theory change. As regards realism, Ian Hacking’s contribution has been to introduce ‘intervention’ as the basis of realism. He also proposed, following Imre Lakatos, to replace the issue of truth with progress and rationality. In this context we examine the case of the vitalism — reductionism debate (...) in biology inspired by the works of Indian physicist-turned-biologist Jagadish Chandra Bose (1858–1937), in the early twentieth century. Both camps had their characteristic hardcores. Vitalists led by John S. Burdon-Sanderson and Augustus D. Waller accepted religious metaphysics to support their research programme, which ultimately degenerated. Bose worked more with the ideals of science such as Occam’s razor, large-scale systematization of phenomena and novel prediction. I argue that his religious metaphysics, instead of acting as a protective shield, helped him to consolidate his position and allowed further problem shift resulting in a research programme that involved consciousness too. His research programme remains relevant even today. (shrink)

In this paper the sameness and difference between two distinguished Indian authors, Rokeya Sakhawat Hossain (1880–1932) and Mahasweta Devi (b. 1926), representing two generations almost a century apart, will be under analysis in order to trace the generational transformation in women’s writing in India, especially Bengal. Situated in the colonial and postcolonial frames of history, Hossain and Mahasweta Devi may be contextualized differently. At the same time their subjects are also differently categorized; the former is not particularly concerned with subalterns (...) whereas the latter specifically focuses on the effect of race and class on gender. The quest for the ‘self’ and ‘subjectivity’ is more pertinent in the latter and consequently the appeal for agency is based on a crude power struggle. Hossain, a philanthropist who championed the woman question, believed that striving for equality should be a collective process which could be achieved by spreading awareness among fellow-inmates inhabiting the prison of patriarchy. Like Euro-American first-wave feminists, Rokeya advocated the necessity of education among women in order for them to be able to comprehend their plight and ‘awake’ for the cause. She addresses fundamental issues of feminism like education and the systematized claustrophobia within the domestic space. Whereas Mahasweta Devi, has been an activist writer who is regarded as the brand ambassador for the support of the marginalized, deprived and denotified tribes of India. It is her mission to provide succour to the marginalized sections, especially tribes from the Purulia district of West Bengal, like the Kherias and Shabars. As an activist writer she explores tribal life and allied socio-political issues which reflect their agony. (shrink)

The diversity of knowledge surrounding behavioural insights (BI) means in the policy sciences, although visible, remains under-theorized with scant comparative and generalizable explorations of the procedural prerequisites for their effective design, both as stand-alone tools and as part of dedicated policy 'toolkits'. While comparative analyses of the content of BI tools has proliferated, the knowledge gap about the procedural needs of BI policy design is growing recognizably, as the range of BI responses grows in practice necessitating specific capabilities, processes and (...) institutional frameworks to be in place for their design. This Element draws on the literature on policy design and innovation adoption to explore the administrative, institutional and capacity endowments of governments for the successful and appropriate integration of BI in existing policy frameworks. Further, we present three illustrative cases with respect to their experience of essential procedural endowments facilitating for the effective integration of BI in policy design. (shrink)

This book deals with one of the most unique and challenging themes that the mind of man has ever faced: The Evolutionary Destiny of the Human Body. Though apparently a marvellous product of biological evolution man's physical body – with its proneness to disease, its constant subjection to fatigue and inertia, its decaying process and final disappearance at death – is full of limitations. But are these limitations something permanent and insuperable? In this book we have a treatment both metaphysical (...) and scientific based on the profound vision of Sri Aurobindo and the Mother on this most unusual subject. (shrink)

This volume constitutes a lucid introduction to methodology in social research. It will enable social science researchers trained in a particular field to look beyond and relate to other methodological domains.

1. Manipur is a state in the Northeast region of India with a history of ongoing militarized social structure. ‘Northeast’ is a term used to label an entire region by the Indian state, which has a...

The paper outlines an indigenous approach to managerial transformation for TQM primarily based on the classical wisdom literature of India. It lays emphasis on the transformation of the subjective domain of the individual as a prior requirement for ensuring quality in other dimensions of the organization. An indepth exploration of a model of the human being, purpose of life and meaning of work have been attempted with specific methodological implications for the individual and the organization. Finally, it provides directions for (...) a transformational HRD endeavour covering issues like personality development, leadership, teamwork and communication for TQM effectiveness. (shrink)

Among the billions of persons journeying towards self-discovery, one is living in Mumbai, India. A woman, revelling in the roles of daughter and sister, wife and mother, teacher and writer. The three decades of her lifetime have seen lessons on faith and patience served to her in various interesting forms. And she has, almost magically, found guidance through friends and strangers alike at the 'right' times. She makes plenty of mistakes. Yet she sticks with childlike tenacity to her belief that (...) the path ofgenuineness brings life to a splendid culmination. January 2001 saw the opening of a new window in her heart-space—the introduction of the quality mind process (QMP), which she and others participated in during the week-long workshop on values and ethics at IIM Calcutta, India. She is yet to completely appreciate the magnificence of this new channel. Yet the shifis in feeling, thinking, speaking and behaving that she found happening due to the QMP have made her forever grateful. This is the essay she wrote, with descriptions of happenings woven with reflections from her journal, to narrate as best as she could the journey of the year with QMP. (shrink)

In this paper we introduce the concept of interval valued neutrosophic soft topological space together with interval valued neutrosophic soft finer and interval valued neutrosophic soft coarser topology. We also define interval valued neutrosophic interior and closer of an interval valued neutrosophic soft set. Some theorems and examples are cites. Interval valued neutrosophic soft subspace topology are studied. Some examples and theorems regarding this concept are presented.

There is growing global consensus that inequality is making sustainable development goals unattainable. Social inclusion of the historically marginalized and equality of opportunity is crucial for sustainable development. Inclusive quality education for all is therefore considered as one of the three main targets for sustainable development according to UNESCO’s Incheon declaration in 2015. This paper draws on an institutional ethnography of a globally interconnected old colonial school’s inclusive pedagogic work in postcolonial India. The school’s work has been much celebrated in (...) existing research by academics, global donor agencies and also by the Indian government’s Sarva Shikshya Abhiyan office. This paper analyses how the school conceptualized a distinct inclusive pedagogy to educate the hearts and the minds of children driven by local community needs for social inclusion within a context of extreme inequality. This paper argues that the school’s conception of inclusive education addressing the diverse learning needs of children developed as a syncretic cultural formation drawing on its institutional mission for social justice, as well as indigenous history of educational reform and philosophy of community engagement. In doing so, this paper engages with the ‘philosophy of context’ and draws on the ‘southern theory’ of inclusive education as envisioned by Rabindranath Tagore, indigenous education reformer and Nobel Laureate poet activist during early twentieth-century colonial British India, who challenged both local and global inequality through his creative and educational work. (shrink)

The process of obtaining informed consent to participate in a clinical study presents many challenges for research conducted in a population of patients with schizophrenia. Morally valid, informed consent must include information sharing, decisional capacity, and capacity for voluntarism. This paper examines the unique features of schizophrenia that may threaten each of these elements of informed consent, and it proposes additional safeguards in the process of gaining informed consent from individuals with schizophrenia in order to maximise the decision-making potential of (...) this patient population. (shrink)

The book highlights the concept of ontology, relationship between language and ontology, the distinction between ontology and reality, the role of linguistic philosophers in dealing with ontology etc. Apart from these, the eminent scholars address themselves with the ontology behind the value of valuation, exclusion and discrimination, inter-religious dialogue, Indian theories of language, values in cinema, poetic language etc.

In the past few decades, increased awareness of environmental pollution has led to the exploitation of microbial metabolic potential in the construction of several genetically engineered microorganisms (GEMs) for bioremediation purposes. At the same time, environmental concerns and regulatory constraints have limited the in situ application of GEMs, the ultimate objective behind their development. In order to address the anticipated risks due to the uncontrolled survival/dispersal of GEMs or recombinant plasmids into the environment, some attempts have been made to construct (...) systems that would contain the released organisms. This article discusses the designing of safer genetically engineered organisms for environmental release with specific emphasis on the use of bacterial plasmid addiction systems to limit their survival thus minimizing the anticipated risk. We also conceptualize a novel strategy to construct “Suicidal Genetically Engineered Microorganisms (SGEMs)” by exploring/combining the knowledge of different plasmid addiction systems (such as antisense RNA‐regulated plasmid addiction, proteic plasmid addiction etc.) and inducible degradative operons of bacteria. BioEssays 27:563–573, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

Embryos and microscopes share a long, remarkable history and biologists have always been intrigued to watch how embryos develop under the microscope. Here we discuss the advances in microscopy which have greatly influenced our current understanding of embryogenesis. We highlight the evolution of microscopes and the optical technologies that have been instrumental in studying various developmental processes. These imaging modalities provide mechanistic insights into the dynamic cellular and molecular events which drive lineage commitment and morphogenetic changes in the developing embryo. (...) We begin the journey with a brief history of microscopy to study embryos. First, we review the principles and optics of light, fluorescence, confocal, and electron microscopy which have been key techniques for imaging cellular and molecular events during embryonic development. Next, we discuss recent key imaging modalities such as light‐sheet microscopy, which are suitable for whole embryo imaging. Further, we highlight imaging techniques like multiphoton and super resolution microscopy for beyond light diffraction limit, high resolution imaging. Lastly, we review some of the scattering‐based imaging methods and techniques used for imaging human embryos. (shrink)

In this technology-driven Digital Age, Management Education is primarily engaged in development of skills and techno-economic competence of students with dominant thrust on sharpening their rational faculties and quantitative ability. Deeper questions and nobler qualittative issues like Spirituality, Corporate Social Responsibility and Ethics are naturally assigned low priority in the rush for money, career, fame, power and position both at the individual and organizational levels. The present paper engages in a Qualitative Research by conducting Focus group Interviews among Participants at (...) the Undergraduate level who had taken up Management Education. After content analysis of the responses the authors highlight their observations on the existing gaps in prevailing management education leading to failure of the present system in charging the students with a deeper Meaning of Work and a higher Purpose of Life. The paper then delves into exploration in pertinent tenets of Classical Indian Wisdom to enrich the spectrum of Management education with insights on Humanistic Philosophy, Holistic Learning, Enlightened CSR and Ethics, and Inspirational Leadership towards creating a better and more humane future for modern organizations. (shrink)

As ethics consultants on a busy consult service in a large urban setting, we would approach this case by gathering more information and context. This involves clarifying the clinical facts, underst...

Knowledge and action constitute two important and inter-related domains of human existence. The very pace of our modern life with all its material abundance hardly allows us space for the dawning of higher knowledge or scope for imparting deeper meaning into the endless series of our mechanical actions. The limitations of linear thinking, binary logic and specialized disciplines of knowledge prevent our access to a holistic perception of our life-world. The article draws insights from three classical traditions of learning to (...) highlight the importance of conversations and dialogues as alternative and non-conventional sources of creating and disseminating actionable knowledge. The author delves into a depth exploration of three timeless masterpieces of world literature and philosophy for a comprehensive understanding of the drama of life and death and attempts to create a space for unconditional love in our quest of illumined knowledge and engagement in meaningful action. (shrink)

v. 1. March 1897-February 1898 -- v. 2. March 1898-July 1899.