The obesity epidemic among children and adolescents in the United States continues to worsen. The most recent analysis of data from the National Health and Nutrition Examination Survey showed that the prevalence of overweight among children and adolescents – defined as a Body Mass Index at or above the 95th percentile on gender-specific BMI-for-age growth charts developed by the Centers for Disease Control and Prevention – increased significantly between 1999-2000 and 2003-2004. Over this period, the prevalence of overweight among children (...) and adolescents aged 2-19 increased 23% – from 13.9% to 17.1%. In 2003-2004, 18.8% of children aged 6-11 and 17.4% of adolescents aged 12-19 were overweight. Roughly comparable proportions of each age group were considered to be at risk of becoming overweight. (shrink)

Denić ( 2018, 2019, To appear ) observes that the availability of distributive inferences—for sentences with disjunction embedded in the scope of a universal quantifier—depends on the size of the domain quantified over as it relates to the number of disjuncts. Based on her observations, she argues that probabilistic considerations play a role in the computation of implicatures. In this paper we explore a different possibility. We argue for a modification of Denić’s generalization, and provide an explanation that is based (...) on intricate logical computations but is blind to probabilities. The explanation is based on the observation that when the domain size is no larger than the number of disjuncts, universal and existential alternatives are equivalent if distributive inferences are obtained. We argue that under such conditions a general ban on ‘fatal competition’ (Magri 2009a, b, Spector 2014 ) is activated, thereby predicting distributive inferences to be unavailable. (shrink)

The discourse marker use of the word like is considered by many to be superfluously sprinkled into talk, a bad habit best avoided. But a comparison of the use of like in successive tellings of stories demonstrates that like can be anticipated in advance and planned into stories. In this way, like is similar to other words and phrases tellers recycle during story telling. The anticipation of like contrasted with the uses of other discourse markers such as oh, you know, (...) and well, which almost never re-occurred in similar locations across tellings. Um and uh did sometimes re-occur; these uses are contrasted with like. Although discourse markers are generally used on the fly to handle various issues that come up in coordinating talk as it unfolds, like can be used as an integral part of the story -a marked contrast to the prevalent idea that likes are speech tics. (shrink)

The COVID-19 pandemic has had a global effect. The disproportionate impact on Indigenous peoples and racialized groups has brought ethical challenges to the forefront in research and clinical practice. In Canada, the Tri-Council Policy Statement (TCPS2), and specifically the principle of justice, emphasizes additional care for individuals “whose circumstances make them vulnerable”, including Indigenous and racialized communities. In the absence of race-based data to measure and inform health research and clinical practice, we run the risk of causing more harm and (...) contributing to ongoing injustices. However, without an accepted framework for collecting, maintaining, and reporting race-based data in Canada, more guidance is needed on how to do this well. Importantly, a framework for collecting race-based data should build on existing guidance from Indigenous and other structurally marginalized communities, the TCPS2, recommendations from the World Health Organization, and involve relevant stakeholders. In this paper, we describe historical examples of unethical studies on Indigenous and racialized groups, discuss the challenges and potential benefits of collecting race-based data, and conclude with objectives for a pan-Canadian framework to inform how race-based data is collected, stored, and accessed in health research. (shrink)

We explored the differential impact of auditory information and written contextual information on the recognition of verbal irony in spontaneous speech. Based on relevance theory, we predicted that speakers would provide acoustic disambiguation cues when speaking in situations that lack other sources of information, such as a visual channel. We further predicted that listeners would use this information, in addition to context, when interpreting the utterances. People were presented with spontaneously produced ironic and nonironic utterances from radio talk shows in (...) written or auditory form, with or without written contextual information. When the utterances were read without written contextual information, all utterances were rated as equally ironic. But when they were heard as opposed to read, or when they were presented in irony-biasing contexts, originally ironic utterances were rated as more sarcastic than originally nonironic utterances. This evidence suggests both acoustic and contextual information are used when inferring ironic intent in spontaneous speech, and validates previous manipulations of intonation in studies of irony understanding. (shrink)

Book reviewed in this article: The Puzzle People: Memoirs of a Transplant Surgeon. By Thomas E. Starzl.

The coming of bioethics -- The coming of bioethicists -- "Choices on our conscience": the inauguration of the Kennedy Institute of Education -- "Hello, Dolly": bioethics in the media -- Celebrating bioethics and bioethicists -- Thinking socially and culturally in bioethics -- Reminiscences of observing participants -- Bioethics circles the globe -- Bioethics in France -- The development of bioethics in the Islamic Republic of Pakistan -- The coming of the culture wars to American bioethics.

We propose a modification of the exhaustivity operator from Fox Presupposition and implicature in compositional semantics, Palgrave Macmillan, London, pp 71–120, 2007. https://doi.org/10.1057/9780230210752_4) that on top of negating all the Innocently Excludable alternatives affirms all the ‘Innocently Includable’ ones. The main result of supplementing the notion of Innocent Exclusion with that of Innocent Inclusion is that it allows the exhaustivity operator to identify cells in the partition induced by the set of alternatives whenever possible. We argue for this property of (...) ‘cell identification’ based on the simplification of disjunctive antecedents and the effects on free choice that arise as the result of the introduction of universal quantifiers. We further argue for our proposal based on the interaction of only with free choice disjunction. (shrink)

High-spin states have been studied in Pr-135(59), populated through the Cd-116(Na-23,4n) reaction at 115 MeV, using the Gammasphere gamma-ray spectrometer. The negative-parity yrast band has been significantly extended to spin similar to 45 (h) over bar and excitation energy 21.5 MeV, showing evidence for several rotational alignments. The positive-parity yrast band of Ce-135(58), populated through the p4n channel of this reaction, was also populated to spin similar to 38 (h) over bar and excitation energy 18 MeV. Cranking calculations indicate that (...) these nuclei are soft with respect to the triaxiality parameter gamma and that several competing nuclear shapes occur at high spin. (shrink)

(Series copy) The new Oxford Readings in Feminism series maps the dramatic influence of feminist theory on every branch of academic knowledge. Offering feminist perspectives on disciplines from history to science, each book assembles the most important articles written on its field in the last ten to fifteen years. Old stereotypes are challenged and traditional attitudes upset in these lively-- and sometimes controversial--volumes, all of which are edited by feminists prominent in their particular field. Comprehensive, accessible, and intellectually daring, the (...) Oxford Readings in Feminism series is vital reading for anyone interested in the effects of feminist ideas within the academy. Can science be gender-neutral? In recent years, feminist critics have raised troubling questions about the practice and goals of traditional science, demonstrating the existence of a pervasive bias in the ways in which scientists conduct and discuss their work. This exciting volume gathers seventeen essays--by sociologists, scientists, historians, and philosophers--of seminal significance in the emerging field of feminist science studies. Analyzing topics from the stereotype of the "Man of Reason" to the "romantic" language of reproductive biology, these fascinating essays challenge readers to take a fresh look at the limitations--and possibilities--of scientific knowledge. (shrink)

It has long been known that the red blood cell contains a membrane skeleton that stabilizes the plasma membrane, determines its shape, and regulates the lateral distribution of the membrane glyco‐proteins to which it is attached. The way in which these functions are regulated in other cells has not been understood. It has now been shown that platelets also contain a membrane skeleton. In contrast to the membrane skeleton of the red blood cell, the platelet membrane skeleton has actin‐binding protein, (...) not spectrin, as a major component. The platelet membrane skeleton regulates the same cellular functions as the red blood cell membrane skeleton. Other cells may contain a membrane skeleton that is critical to their viability and normal functioning. (shrink)

Words like well, oh, and you know have long been observed and studied in spontaneous speech. With the proliferation of on-line dialogues, such as instant messaging between friends or back-and-forth postings at websites, there are increasing opportunities to observe them in spontaneous writing. In Experiment 1, the interpretation of discourse markers in on-line debates was compared to proposed functions of those markers identified in other settings. In Experiment 2, the use of discourse markers in spontaneous speech was compared to their (...) uses in spontaneous writing. Results support the conclusion that although they vary in frequency in spoken versus written domains, discourse markers are used similarly across domains, but with particular communicative functions that make them non-interchangeable. (shrink)

Observing others in conversation is a common format for comprehending language, yet little work has been done to understand dialog comprehension. We tested whether overhearers use addressee backchannels as predictive cues for how to integrate information across speaker turns during comprehension of spontaneously produced collaborative narration. In Experiment 1, words that followed specific backchannels were recognized more slowly than words that followed either generic backchannels or pauses. In Experiment 2, we found that when the turn after the backchannel was a (...) continuation of the narrative, specific backchannels prompted the fastest verification of prior information. When the turn after was an elaboration, they prompted the slowest, indicating that overhearers took specific backchannels as cues to integrate preceding talk with subsequent talk. These findings demonstrate that overhearers capitalize on the predictive relationship between backchannels and the development of speakers’ talk, coordinating information across conversational roles. (shrink)

Functional near-infrared spectroscopy is a neuroimaging technique that has undergone tremendous growth over the last decade due to methodological advantages over other measures of brain activation. The action-observation network, a system of brain structures proposed to have “mirroring” abilities, has been studied in humans through neural measures such as fMRI and electroencephalogram ; however, limitations of these methods are problematic for AON paradigms. For this reason, fNIRS is proposed as a solution to investigating the AON in humans. The present review (...) article briefly summarizes previous neural findings in the AON and examines the state of AON research using fNIRS in adults. A total of 14 fNIRS articles are discussed, paying particular attention to methodological choices and considerations while summarizing the general findings to aid in developing better protocols to study the AON through fNIRS. Additionally, future directions of this work are discussed, specifically in relation to researching AON development and potential multimodal imaging applications. (shrink)

Soft X‐ray tomography (SXT) is an imaging technique capable of characterizing and quantifying the structural phenotype of cells. In particular, SXT is used to visualize the internal architecture of fully hydrated, intact eukaryotic and prokaryotic cells at high spatial resolution (50 nm or better). Image contrast in SXT is derived from the biochemical composition of the cell, and obtained without the need to use potentially damaging contrast‐enhancing agents, such as heavy metals. The cells are simply cryopreserved prior to imaging, and (...) are therefore imaged in a near‐native state. As a complement to structural imaging by SXT, the same specimen can now be imaged by correlated cryo‐light microscopy. By combining data from these two modalities specific molecules can be localized directly within the framework of a high‐resolution, three‐dimensional reconstruction of the cell. This combination of data types allows sophisticated analyses to be carried out on the impact of environmental and/or genetic factors on cell phenotypes. (shrink)

The proposal by Clarke and Beck offers a new explanation for the association between the approximate number system and math. Previous explanations have largely relied on developmental arguments, an underspecified notion of the ANS as an “error detection mechanism,” or affective factors. The proposal that the ANS represents rational numbers suggests that it may directly support a broader range of math skills.

Small talk plays a big role in conversational perception. In the study here, pairs of conversational participants engaged in three iterations of an ecologically valid task-break dialogue where the break was either small talk via videoconferencing or waiting the same amount of time with cameras and mics turned off. Small talk increased conversational participants’ enjoyment of conversations, their willingness to engage in future conversations with their addressees, and their actual engagement in unprompted conversations with their addressees. Dyads who were instructed (...) to engage in small talk conversation during breaks were approximately three and a half times more likely to have conversations in the sixty second unprompted conversation period at the end of the study compared to dyads whose cameras and mics were off during the earlier break periods. Reciprocity effects previously observed in audio-only and text-only communication were not observed in this study. The findings presented here demonstrate that not only can the positive influence of small talk be replicated and extended to videoconferencing interactions, but such talk can also lead to an increased desire for continued interactions with conversational partners. (shrink)

This article addresses how bodily integrity has been mobilised in the context of genital cutting of male infants and the extent to which the concept is taken into account in legal decision-making in the United Kingdom. While bioethicists have debated whether interventions on children's bodies are more appropriately determined on the basis of hypothetical consent or in the child's best interest, it is clear that in law the relevant test is whether interventions are in the child's best interest. As the (...) issue of nonconsensual genital cutting of infants has become more contested, courts have been asked to adjudicate on the best interests of infants in situations where their caregivers disagree about procedures. Although this body of jurisprudence remains (surprisingly) small, in this article we argue that, while there are now discernible trends in such cases (e.g. deferring decision-making until the child has the requisite capacity to decide, engaging with certain human rights norms), too often judicial reasoning about a child's best interests remains largely empty of reasoned content, and in certain respects is regressing. Using the recent case of Re P to exemplify this logic, and drawing on our previous work advocating the value of embodied integrity, we argue that judges should adopt a more substantive framework of values in judging the child's corporeal and other interests in such cases. This would move best interests assessments beyond a mere formalistic exercise and lead to better reasoned legal judgements. (shrink)

It is well known that in certain environments the scope of a moved quantifier phrase can be determined at either its pre-movement position (“scope reconstruction”) or its postmovement position (“surface scope”). Thus the familiar ambiguity of (1) results from two choices for the scope of the moved QP. Under scope reconstruction, the scope of the moved existential QP is the sister of the pre-movement position (i.e. the sister of t, [to win the lottery]), while under surface scope it is the (...) sister of the post-movement position (i.e. [is likely t to win the lottery]). The two scope possibilities yield different semantic interpretations, corresponding to the paraphrases in (2). (1) Someone from New York is likely t to win the lottery (2) a. It is likely that there will be someone from New York who wins the lottery.. (shrink)

There has recently been considerable discussion of the relative merits of deep ecology and ecofeminism, primarily from an ecofeminist perspective. I argue that the essential ecofeminist charge against deep ecology is that deep ecology focuses on the issue of anthropocentrism (i.e., human-centeredness) rather than androcentrism (i.e., malecenteredness). I point out that this charge is not directed at deep ecology’s positive or constructive task of encouraging an attitude of ecocentric egalitarianism, but rather at deep ecology's negative or critical task of dismantling (...) anthropocentrism. I outline a number of problems that can attend not only the ecofeminist critique of deep ecology, but also comparable critiques that proceed from a broad range of social and political perspectives. I then proceed to argue that deep ecology’s concem with anthropocentrism is entirely defensible-and defensible in a way that should be seen as complementing and expanding the focus of radical social and political critiques rather thanin terms of these approaches versus deep ecology. (shrink)

This paper argues that “covert” operations like Quantifier Raising (QR) can precede “overt” operations. Specifically we argue that there are overt operations that must take the output of QR as their input. If this argument is successful there are two interesting consequences for the theory of grammar. First, there cannot be a “covert” (i.e. post-spellout) component of the grammar. That is, what distinguishes operations that affect phonology from those that do not cannot be an arbitrary point in the derivation (“spellout”) (...) before which the former apply and after which the latter do; all syntactic operations apply in the same component (henceforth ‘single component grammar’). Second, there must be some alternative means for distinguishing “overt” from “covert” operations. One such alternative, which we can call the ‘phonological theory of QR’, was suggested by Bobaljik (1995), Pesetsky (1998), Groat and O’Neil (1994). These authors proposed that the distinguishing property has to do with principles of the syntax-phonology interface. Assume that movement is a copying operation with phonology targeting one copy in a chain for pronunciation. The distinction between “overt” and “covert” movement, these authors suggest, is this: “overt” movements are the result of phonology targeting the head of a chain for.. (shrink)

Dai Jinhua _Cinema and Desire: Feminist Marxism and Cultural Politics in the Work of Dai Jinhua_ Edited by Jing Wang and Tani E. Barlow London and New York: Verso, 2002 ISBN 1-85984-264-X 280 pp.

I will discuss those epistemic accounts of truth that say, roughly and at least, that the truth is what all ideally rational people, with maximum evidence, would in the long run come to believe. They have been defended on the grounds that they can solve sceptical problems that traditional accounts cannot surmount, and that they explain the value of truth in ways that traditional (and particularly, minimal) accounts cannot; they have been attacked on the grounds that they collapse into idealism. (...) I show that all these claims are mistaken. The system of statements accepted by an adherent of an epistemic account who also accepts the equivalence scheme is the same as that accepted by an adherent of a traditional account who also accepts a remarkably strong thesis of epistemic optimism. The singling out of one rather than another claim within this system as defining 'true' cannot make as much difference as to imply idealism or refute scepticism. However, it can make all the difference when it is a matter of explaining the value of truth. For a crucial point in such explanation depends on what can be soundly substituted for what in intensional contexts; above all those governed by such verbs as 'know', 'hope', 'believe', 'value'. That is, it depends on what expressions are intensionally equivalent. And one point of singling out one formulation as definitional can be to settle just this. But though some epistemic theorists have deemed ability to explain the value of truth a merit of their account (and lack of this ability a fatal defect of traditional accounts, of minimal accounts in particular), it turns out that minimal accounts of 'true' fit a sound account of our valuing of truth in a way that epistemic accounts do not. In the course of this argument I rebut related positions: e.g. Dummett's, that minimal definitions fail because they cannot account for the point of having a notion of truth, and that an account of the practice of assertion is what would fill this lacuna. I argue to the contrary that if the point of the notion could not be explained on the basis of a traditional definition, it could not be explained at all. (shrink)

The volume documents, and makes an original contribution to, an astonishing period in twentieth-century philosophy—the progress of Arne Naess's ecophilosophy from its inception to the present. It includes Naess's most crucial polemics with leading thinkers, drawn from sources as diverse as scholarly articles, correspondence, TV interviews and unpublished exchanges. The book testifies to the skeptical and self-correcting aspects of Naess's vision, which has deepened and broadened to include third world and feminist perspectives. Philosophical Dialogues is an essential addition to the (...) literature on environmental philosophy. (shrink)

The ethical recruitment of participants with neurological disorders in clinical research requires obtaining initial and ongoing informed consent. The purpose of this study is to characterize barriers faced by research personnel in obtaining informed consent from research participants with neurological disorders and to identify strategies applied by researchers to overcome those barriers. This study was designed as a web-based survey of US researchers with an optional follow-up interview. A subset of participants who completed the survey were selected using a stratified (...) purposeful sampling strategy and invited to participate in an in-depth qualitative interview by phone or video conference. Data were analyzed using a mixed methods approach, including content analysis of survey responses and thematic analysis of interview responses. Over 1 year, 113 survey responses were received from US research personnel directly involved in obtaining informed consent from participants in neurological research. Frequently identified barriers to informed consent included: cognitive and communication impairments (e.g. aphasia), unrealistic expectations of research participants, mistrust of medical research, time constraints, literacy barriers, lack of available social support, and practical or resource-related constraints. Strategies to enhance informed consent included: involving close others to support participant understanding of study-related information, collaborating with more experienced research personnel to facilitate training in obtaining informed consent, encouraging participants to review consent forms in advance of consent discussions, and using printed materials and visual references. Beyond conveying study-related information, researchers included in this study endorsed ethical responsibilities to support deliberation necessary to informed consent in the context of misconceptions about research, unrealistic expectations, limited understanding, mistrust, and/or pressure from close others. Findings highlight the importance of training researchers involved in obtaining informed consent in neurological research to address disease-specific challenges and to support the decision-making processes of potential research participants and their close others. (shrink)

Metabolic pathways underlying brain function remain largely unexplored during neurodevelopment, predominantly due to the lack of feasible techniques for use with awake infants. Broadband near-infrared spectroscopy provides the opportunity to explore the relationship between cerebral energy metabolism and blood oxygenation/haemodynamics through the measurement of changes in the oxidation state of mitochondrial respiratory chain enzyme cytochrome-c-oxidase alongside haemodynamic changes. We used a bNIRS system to measure ΔoxCCO and haemodynamics during functional activation in a group of 42 typically developing infants aged between (...) 4 and 7 months. bNIRS measurements were made over the right hemisphere over temporal, parietal and central cortical regions, in response to social and non-social visual and auditory stimuli. Both ΔoxCCO and Δ[HbO2] displayed larger activation for the social condition in comparison to the non-social condition. Integration of haemodynamic and metabolic signals revealed networks of stimulus-selective cortical regions that were not apparent from analysis of the individual bNIRS signals. These results provide the first spatially resolved measures of cerebral metabolic activity alongside haemodynamics during functional activation in infants. Measuring synchronised changes in metabolism and haemodynamics have the potential for uncovering the development of cortical specialisation in early infancy. (shrink)

Backchannel choices affect conversational development. Some backchannels invite interlocutors to continue to the next part of what they are saying and others invite them to elaborate on what they have just said. We tested how communicative modality (audiovisual, audio, text), environmental setting (wholly in-lab, partially in the wild), and conversational goals (on-task, off-task) influenced backchannel usage by participants. We found that backchannel production depends on modality, setting, and goals. For example, we found that specific backchannels played a more prominent role (...) in self-motivated dialogue. Knowledge of how backchannels are used has both theoretical and practical implications. (shrink)

What is it that semanticists think they are doing when using formalisation? What kind of endeavour is the formal semantics of natural language: scientific; linguistic; philosophical; logical; mathematical? If formal semantics is a scientific endeavour, then there ought to be empirical criteria for determining whether such a theory is correct, or an improvement on an alternative account. The question then arises as to the nature of the evidence that is being accounted for. It could be argued that the empirical questions (...) are little different in kind to other aspects of linguistic analysis, involving questions of performance and competence (Chomsky 1965; Saussure 1916). But there are aspects of formal accounts of meaning that appear to sit outside this scientific realm. One key issue concerns the precise nature of the formalisation that is adopted; what criteria are to be used to decide between accounts that are founded on different formal systems, with different ontological assumptions? Indeed, is it necessary to judge semantic frameworks on such grounds? In other words, are two theoretical accounts to be treated as equivalent for all relevant purposes if they account for exactly the same linguistic data? Broadly speaking, there are two related perspectives on the analysis of propositional statements, one “truth conditional” — reducing sentence meaning to the conditions under which the sentence is judged to be true (e.g. Montague 1973) — the other “proof theoretic” — reducing sentence meanings to patterns of entailments that are supported (e.g. Ranta 1994, Fox & Lappin 2005 ,Fox 2000). Variations of these perspectives might be required in the case of non-assertoric utterances. We may wonder what critieria might be used to decide between these approaches. This brings us back to the nature of the data itself. If the data is (merely) about which arguments, or truth conditions, subjects agree with, and which they disagree with, then the terms in which the theory is expressed may be irrelevant. But it may also be legitimate to be concerned with either (a) the intuitions that people have when reasoning with language, or (b) some technical or philosophical issues relating to the chosen formalism. The truth-conditional vs proof-theoretic dichotomy might broadly be characterised as model-theoretic vs axiomatic, where the model-theoretic tend to be built around a pre-existing formal theory, and the axiomatic involves formulating rules of behaviour “from scratch”. In some sense, fitting an analysis of a new problem into an existing framework could be described as providing some kind of “explanatory” power, assuming that the existing framework has some salient motivation that is independent of the specific details of the phenomena in question. In contrast, building a new theory that captures the behaviour might then be characterised as “descriptive”, as — superficially at least — it does not show how an existing theory “already” accounts for the data in some sense. Here we observe instead that the argument can be run in the other direction. that a reductive model-theoretic account merely “describes” how some aspects of a problem can be reduced to some formalisation, but may fail to capture a subject’s understanding or intuitions about meaning. It is surely appropriate for the formal theory itself to be at least sympathetic to the ontological concerns and intuitions of its subjects — if not inform them (Dummett 1991). The alternative amounts to little more than carving out otherwise arbitrary aspects of a system that mimics the required behaviour, without a coherent explanation of why some aspects of a formal theory characterise, or capture, the intended meaning, but not others (cf. Benacerraf 1965). That seems an impoverished approach, weakening any claim to “explain”. Any constraint this imposes on what is it to be an explanatory account of meaning then faces the same problem as naive notions of compositionality (Zadrozny 1994) — that is, what appears to be a meaningful restriction is, in reality, a mirage. (shrink)