Like most bilaterian animals, the annelid Platynereis dumerilii generates the majority of its body axis in an anterior to posterior temporal progression with new segments added sequentially. This process relies on a posterior subterminal proliferative body region, known as the "segment addition zone" (SAZ). We explored some of the molecular and cellular aspects of posterior elongation in Platynereis, in particular to test the hypothesis that the SAZ contains a specific set of stem cells dedicated to posterior elongation.We cloned and characterized (...) the developmental expression patterns of orthologs of 17 genes known to be involved in the formation, behavior, or maintenance of stem cells in other metazoan models. These genes encode RNA-binding proteins(e.g., tudor, musashi, pumilio) or transcription factors(e.g., myc, id, runx) widely conserved in eumetazoans. Most of these genes are expressed both in the migrating primordial germ cells and in overlapping ring-like patterns in the SAZ, similar to some previously analyzed genes(piwi, vasa). The SAZ patterns are coincident with the expression of proliferation markers cyclin B and PCNA. EdU pulse and chase experiments suggest that new segments are produced through many rounds of divisions from small populations of teloblast-like posterior stem cells. The shared molecular signature between primordial germ cells and posterior stem cells in Platynereis thus corresponds to an ancestral "stemness" program. (shrink)

For over 20 years, the Schmid Training Course (STC) has offered unique opportunities for marine biology students from European universities to learn about marine model organisms. While the topics of the course have continuously changed over the years with the advent of new research techniques and discoveries, the pedagogical approach has remained largely the same – a combination of lectures, lab practicals, and field excursions. Several life science researchers, who have taught in the STC for many years, sought to bring (...) the course's pedagogical approach into the 21st century, and with the support of Erasmus+ Programme of the European Community funding, the Digital Marine project was developed. Digital Marine began in 2018 as an international partnership between the six research centers from which the STC instructors hail, and its main objective was to introduce a flipped, blended approach to learning and teaching with respect to established and emerging marine biological model systems. The Digital Marine platform, which covers 12 marine model organisms, is now publicly available. (shrink)

Sponges branch basally in the metazoan phylogenetic tree and are believed to be composed of four distinct lineages with still uncertain relationships. Indeed, some molecular studies propose that Homoscleromorpha may be a fourth Sponge lineage, distinct from Demospongiae in which they were traditionally classified. They harbour many features that distinguish them from other sponges and are more evocative of those of the eumetazoans. They are notably the only sponges to possess a basement membrane with collagen IV and specialized cell‐junctions, thus (...) possessing true epithelia. Among Homoscleromorphs, we have chosen Oscarella lobularis as a model species. This common and easily accessible sponge is characterized by relatively simple histology and cell composition, absence of skeleton, and strongly pronounced epithelial structure. In this review, we explore the specific features that make O. lobularis a promising homoscleromorph sponge model for evolutionary and developmental researches. (shrink)

This book offers a new approach to the analysis of the multiple meanings of English modals, conjunctions, conditionals, and perception verbs. Although such ambiguities cannot easily be accounted for by feature-analyses of word meaning, Eve Sweetser's argument shows that they can be analyzed both readily and systematically. Meaning relationships in general cannot be understood independently of human cognitive structure, including the metaphorical and cultural aspects of that structure. Sweetser shows that both lexical polysemy and pragmatic ambiguity are shaped by our (...) metaphorical folk understanding of epistemic processes and of speech interaction. Similar regularities can be shown to structure the contrast among root, epistemic and speech act uses of modal verbs, multiple uses of conjunctions and conditionals, and certain processes of historical change observed in Indo-European languages. Since polysemy is typically the intermediate step in semantic change, the same regularities observable in polysemy can be extended to an analysis of semantic change. (shrink)

This essay focuses on conceptual engineers who aim to improve other people's patterns of inference and attention by shaping their concepts. Such conceptual engineers sometimes engage in a form of epistemic paternalism that I call paternalistic cognitive engineering: instead of explicitly persuading, informing and educating others, the engineers non-consultatively rely on assumptions about the target agents’ cognitive systems to improve their belief forming. The target agents could reasonably regard such benevolent exercises of control as violating their sovereignty over their own (...) belief formation. This is a pro tanto reason against such engineering. In addition to the relevant projects of conceptual engineering, paternalistic cognitive engineering plausibly includes certain kinds of nudging and evidence suppression. I distinguish the sovereignty-based concern from other ethical worries about conceptual engineering and discuss how one might justify the relevant conceptual engineering projects despite the sovereignty-based reason against them. (shrink)

In this paper, the principal objections to unconditional forgiveness are canvassed, primarily that it fails to take wrongdoing seriously enough, and that it displays a lack of self-respect. It is argued that these objections stem from a mistaken understanding of what forgiveness actually involves, including the erroneous view that forgiveness involves some degree of condoning of the offence, and is incompatible with blaming the offender or punishing him. Two positive reasons for endorsing unconditional forgiveness are considered: respect for persons and (...) human solidarity; and it is argued that the latter provides more plausible grounds for it than the former. (shrink)

Abstract“Science Is Politics By Other Means” (SIPBOM) was coined in The Pasteurization of France, Latour’s 1984 empirical study of the birth of microbiology. Yet, it encapsulates an outstanding political theory of science that Latour has never formalized and that has remained unnoticed to this day. The theory is comprised of two dimensions. The first one is the ontological labor performed by science, that is, the laboratory production of new nonhumans. The second one is the ability of science to devise and (...) implement novel policies targeted at the new beings it produces. These “other means” are incorporated in political projects and contribute to the shaping of society. Fifteen years later, Latour published Politics of Nature ([1999] 2004), a full-blown political treatise equally devoted to the political character of science. It would be mistaken, however, to assume that it falls in the same SIPBOM paradigm as the Pasteur study. The compositionist theory it offers redefines politics as the institution of the nonhumans that make up external reality, a task that has traditionally been monopolized by Science. In this sense, “science is politics by other means” has become “politics is science by other means,” these “other means” now referring to “cosmopolitics,” that is, the due process advocated by compositionism. The first claim of the present paper is that the respective weight ascribed to politics and ontology is different in The Pasteurization of France and in Politics of Nature. The second claim is that compositionism is not as successful as Latour’s early theory to account for the politicity of science. (shrink)

We readily claim that great moral catastrophes such as the Holocaust involve evil in some way, although it' not clear what this amounts to in a secular context. This paper seeks to provide a secular account of what evil is. It examines what is intuitively the most plausible account, namely that the evil act involves the production of great suffering (or other disvalue), and argues that such outcomes are neither necessary nor sufficient for an act to be evil. Only an (...) appeal to distinctive patterns of motivation, so it is argued, will allow us to accommodate our intuitionsabout which acts are evil, and hence will provide an adequate account of the nature of evil. (shrink)

On the day on which Dr Harold Shipman, the Manchester serial killer, was convicted, there was wall-to-wall coverage of it in the media. During the course of one of the many reports, the daughter of one of his victims was interviewed, and asked for her views on why Shipman had acted as he did. What she said was this: she’d tried and tried to understand or explain his deeds, and she could only come to the conclusion that he was a (...) really evil man. In saying this, she clearly meant to convey more than the obvious truth that what Shipman did was very wrong and entirely to be condemned. It seems to me that a secular as well as a religious audience would find the daughter’s appeal to evil as an appropriate explanation perfectly comprehensible. But what exactly was it that was being attributed to Shipman, and how was it thought to explain his actions? (shrink)

Forgiveness usually gets a very good press in our culture: we are deluged with self-help books and television shows all delivering the same message, that forgiveness is good for everyone, and is always the right thing to do. But those who have suffered seriously at the hands of others often and rightly feel that this boosterism about forgiveness is glib and facile. Perhaps forgiveness is not always desirable, especially where the wrongdoing is terrible or the wrongdoer unrepentant. In this book, (...) Garrard and McNaughton suggest that the whole debate suffers from a crippling lack of clarity about what forgiveness really amounts to. They argue that it is more difficult, complex and troubling than many of its advocates suppose. Nevertheless, they conclude, a proper understanding of forgiveness allows us to avoid cheap and shallow forms of it, and enables us to see why it is right and admirable to forgive even unrepentant wrongdoers. (shrink)

I will defend explication, in a Carnapian sense, as a strategy for revisionary ontologists and radical sceptics. The idea is that these revisionary philosophers should explicitly commit to using expressions like “S knows that p” and “Fs exist” differently from how these expressions are used in everyday contexts. I will first motivate this commitment for these revisionary philosophers. Then, I will address the main worries that arise for this strategy: the unintelligibility worry and the topic shift worry. I will focus (...) on the latter worry and provide a solution that makes use of a distinction between practically and theoretically oriented beliefs. On my view, the revisionary philosophers who admit to departing from the everyday language can still criticize everyday knowledge and existence claims, by arguing that while the language embedded in these claims is suitable for beliefs-1, it is not suitable for beliefs-2. (shrink)

I will clarify when and how a tension arises between epistemic environmentalism (a new focus on assessing and improving the epistemic environment) and respect for epistemic autonomy (allowing, empowering, and requiring people to each govern their own beliefs). Using the example of participatory conceptual engineering (improving the linguistic environment through rational discussion with broad participation), I will also identify an option for avoiding the tension—namely, participatory environmentalism. This means a new focus on how people can each contribute to improving the (...) shared epistemic environment through rational deliberation and thereby govern their own beliefs that are shaped by that environment. (shrink)

"These essays advance a reinterpretation of pivotal categories such as self-knowing, moral agency, and altruism.

This article analyzes the institutionalization of the global organic agriculture field and sheds new light on the conventionalization debate. The institutions that shape the field form a tripartite standards regime of governance that links standard-setting, certification, and accreditation activities, in a layering of markets for services that are additional to the market for certified organic products. At each of the three poles of the TSR, i.e., for standard-setting, certification, and accreditation, we describe how the corresponding markets were constructed over time (...) and the role of the different actors in their evolution. We analyze the politics at stake among the actors at each pole, their competing or cooperative interests and visions, and the tensions between them in the promotion of markets. Through the lens of the TSR heuristic, we show that the institutionalization of the organic field beginning in the 1990s and its de facto inclusion in the broader sustainability field beginning in the 2000s contribute to a progressive distancing between the organic movement and its initial political project of alterity, to which public and private actors both contribute actively. As a set of interlinked market institutions, the TSR orients and narrows the scope of debate, which becomes restricted to “market-compatible” dimensions and objects. We conclude that the TSR is a promising heuristic for analyzing contemporary global regulation. (shrink)

In this paper we defend a version of moral internalism and a cognitivist account of motivation against recent criticisms. The internalist thesis we espouse claims that, if an agent believes she has reason to A, then she is motivated to A. Discussion of counter-examples has been clouded by the absence of a clear account of the nature of motivation. While we can only begin to provide such an account in this paper, we do enough to show that our version of (...) internalism can be defended against putative counter-examples. All theories of motivation which take what motivates to be a psychological state run foul of the following plausible constraint: the reason why you ought to do an action and the reason why you do it can be the same. In our view, however, while what motivates is a reason (which is a fact) the state of being motivated is a cognitive stage, viz. the belief that one has reason to act. In cases where the agent's relevant beliefs are false, then she has no reason to act, but nontheless her action can be explained in other ways. (shrink)

Debates regarding clinical ethicists’ scope of practice are not novel and will continue to evolve. Rapid changes in healthcare delivery, outcomes, and expectations have necessitated flexibility in clinical ethicists’ roles whereby hospital-based clinical ethicists are expected to be woven into the institutional fabric in a way that did not exist in more traditional relationships. In this article we discuss three emerging roles: the ethicist embedded in the interdisciplinary team, the ethicist with an expanded educational mandate, and the ethicist as a (...) therapeutic presence in the patient care space. Such expanded capacities offer more robust, positive contributions to institutional culture, stakeholders’ relationships, and patient-centered care. (shrink)

Sustaining hope in patients is an important element of health care, allowing improvement in patient welfare and quality of life. However in the palliative care context, with patients who are terminally ill, it might seem that in order to maintain hope the palliative care practitioner would sometimes have to deceive the patient about the full nature or prospects of their condition by providing a ‘false hope’. This possibility creates an ethical tension in palliative practice, where the beneficent desire to improve (...) patient welfare through sustaining hope appears to be in conflict with an autonomy-based requirement not to deceive patients about their condition. In order to resolve this ethical tension, we provide an analysis of the concept of hope and argue that there is at least one conception – the ‘absolute’ conception of hope – which when properly understood allows practitioners to foster hope in terminally-ill patients while avoiding any need to deceive them about their condition. Practitioners therefore do not need to shy away from using the language of hope in the palliative setting, as on this understanding of hope it can be used in a way that both promotes patient welfare and respects patient autonomy. (shrink)

In the past forty years, Bruno Latour’s claim that Science Is Politics By Other Means (SIPBOM) has been the underlying creed of Science and Technology Studies (STS), most of us simply taking it for granted. In contrast, this special issue is predicated on the observation of an enduring lack of exegesis of this catchphrase so remarkable that is has caused an outcry among natural scientists, echoed in some social science quarters. If SIPBOM has been a resource for decades, by turning (...) it into a topic this special issue revisits one of the most exciting and challenging insights of contemporary thought. (shrink)

This paper considers whether we have any reason to forgive the perpetrators of the most terrible atrocities, such as the Holocaust. On the face of it, we do not have reason to forgive in such cases. But on examination, the principal arguments against forgiveness do not turn out to be persuasive. Two considerations in favour of forgiveness are canvassed: the presence of rational agency in the perpetrators, and the common human nature which they share with us. It is argued that (...) the presence of rational agency does not generate a reason to forgive. However, our common human nature may be sufficient to provide such a reason, and evidence for its general reason-giving power can be seen in phenomena such as vicarious shame, and the moral significance which we attach to the notion of crimes against humanity. A reason for forgiveness based on common human nature will not be a strong one, but a weak reason still has some force. (shrink)

The jury remains out about the bottom-line relevance of organisational spirituality. This article reviews the arguments made thus far, using those sources most commonly cited as providing ‹evidence’ that organisational spirituality adds value to the bottom line. Having collated the evidence, this article offers some observation about the robustness of this existing ‹business case’. It then offers some preliminary conclusions on the literature review, examining the merits of pursuing a ‹business case’ in this field and identifying some specific questions for (...) future research. (shrink)

This article shows that forms of analysis and calculation specific to finance are spreading, and changing valuation processes in various social settings. This perspective is used to contribute to the study of the recent transformations of capitalism, as financialisation is usually seen as marking the past three decades. After defining what is meant by “financialised valuation,” different examples are discussed. Recent developments concerning the valuation of assets in accounting standards and credit risk in banking regulations are used to suggest that (...) colonisation of financial activities by financialised valuations is taking place. Other changes, concerning the valuation of social or cultural activities and environmental issues are also highlighted in order to support the hypothesis of a parallel colonisation of non-financial activities by financialised valuations. Specifically, the language of finance appears to gradually being incorporated into public policies, especially in Europe—and this trend seems to have gathered pace since the 2000s. Some interpretations are proposed to understand why public policies are seemingly increasingly reliant on financialised valuations. (shrink)

There seems to be something self-evident—irresistibly so, to judge from its gleeful propagation—about the use of the phrase, “Jane Austen and the Masturbating Girl,” as the Q.E.D. of phobic narratives about the degeneracy of academic discourse in the humanities. But what? The narrative link between masturbation itself and degeneracy, though a staple of pre-1920s medical and racial science, no longer has any respectable currency. To the contrary: modern views of masturbation tend to place it firmly in the framework of optimistic, (...) hygienic narratives of all-too-normative individual development. When Jane E. Brody, in a recent “Personal Health” column in the NewYork Times, reassures her readers that, according to experts, it is actually entirely possible for people to be healthy without masturbating; “that the practice is not essential to normal development and that no one who thinks it is wrong or sinful should feel he or she must try it”; and that even “’those who have not masturbated … can have perfectly normal sex lives as adults,’” the all but perfectly normal Victorianist may be forgiven for feeling just a little—out of breath.3 In this altered context, the self-evidence of a polemical link between autoeroticism and narratives of wholesale degeneracy 4 draws on a very widely discredited body of psychiatric and eugenic expertise whose only direct historical continuity with late twentieth-century thought has been routed straight through the rhetoric and practice of fascism. But it now draws on this body of expertise under the more acceptable gloss of the modern, trivializing, hygienic-developmental discourse, according to which autoeroticism not only is funny—any sexuality of any power is likely to hover near the threshold of hilarity—but also must be relegated to the inarticulable space of infantility. 3. Jane E. Brody, “Personal Health,” New York Times, 4 Nov. 1987.4. Rosenblatt, “The Universities,” p. 3. Eve Kosofsky Sedgwick is professor of English at Duke University and the author of Between Men: English Literature and Male Homosocial Desire and Epistemology of the Closet. (shrink)

The study of the notion of ideology shows that this corpus lends itself to a wide variety of different definitions. A certain opposition runs all the way through this set of definitions. Ideology would appear to be torn between a conception that emphasises its distortion and dissimulation dimensions and another conception which views as a set of social representations. After rapidly presenting the main characteristics of these two polar extremes, Paul Ricoeur's suggestion that these two conceptions can be united is (...) discussed and illustrated by the concept of the `spirit of capitalism', as defined in the book by Boltanski and Chiapello (1999). It is shown that this constitutes an ideology which is in fact an attempt to encompass both these conceptions. It is also shown that the concept of `trial' as proposed in that book helps greatly to understand how this reconciliation is actually possible. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Eve W. Stoddard REASON ON TRIAL: LEGAL METAPHORS IN THE CRITIQUE OF PURE REASON 6 6 r I 1WO things fill the mind with ever new and increasing admi_I_ ration and awe, the oftener and more steadily we reflect on them: the starry heavens above me and the moral law within me." ' These are perhaps Kant's most well-known and oft-repeated words. They reflect not only the profound feeling (...) that underlies his technical and abstruse treatises, but also his characteristic preoccupation with law. The "starry heavens" are a synecdoche both for the wonder of nature as we perceive it in all its multiplicity, and for the marvel of science's ability to reduce, order, and subdue that infinite multiplicity into a few elegant laws. These two types of law, natural and moral, define the focus of Kant's critical philosophy, and metaphors drawn from jurisprudence pervade all three critiques. In the context of controversial statements on the role of metaphor in philosophical texts by Jacques Derrida, Paul Ricoeur, and Richard Rorty, I will analyze the legal metaphors in the prefaces and Transcendental Deductions of the Critique ofPure Reason. My goal in engaging Kant's texts in this controversy over metaphor is twofold: on the one hand to assess experimentally the value of these positions on metaphor in the history of philosophy, and, on the other hand, to examine the relations between critical conceptualization and insurgent metaphoricity in Kant's carefully elaborated and systematized text. In a textwhose key words are "universal and necessary for all possible experience," contingentand ambiguous metaphors might be expected to cause problematic unravelings. Richard Rorty has argued recently that "the history ofscience, culture and politics" should be viewed "as a history of metaphor rather than of discovery." 2 He compares the creations of new vocabularies to the 245 246Philosophy and Literature invention of "new tools" ("CL," p. 5), alluding to "Nietzsche's definition of truth as a mobile army of metaphors" (p. 6). From Plato's figures of the world as cave and the mind as charioteer with unruly horses, we shift to Locke's view of mind as tahda rasa and Descartes's description of the world as a machine. Rorty's paradigm of cultural history as a history of metaphor enters into an earlier, unresolved debate between Jacques Derrida and Paul Ricoeur over the relationship between metaphor and philosophical discourse. Like Derrida, Rorty follows Nietzsche's claims about metaphor in the history of philosophy, a view Ricoeur wants to disprove so that he can recover the privileged univocity of speculative discourse. However Rorty has nothing in common with die complexity and "invaginated" ambiguities, the dazzling multivocity of Derrida's writing on the economics of metaphor. Although Rorty appears at first to agree with Derrida that there is no truth or reality apart from the linguistic tropes which dominate different epochs and cultures, he retains a metaphysical distinction between literal reference and figurative play. Rorty adopts Donald Davidson's theory that metaphors do not have "meaning" precisely because diey have no place in the language game into which they are inserted. They produce an effect, but it is not meaning: "One can only savour it or spit it out"; it is not a " 'truth-value candidate' " ("CL," p. 6). However, through repeated use, the metaphor will find a role in the language game; dying as a metaphor, it will live as a literal statement. Therefore Rorty agrees with Ricoeur that a moribund metaphor is no longer a metaphor, but a literally functioning segment of discourse. Thus despite his initial move toward a Derridean, or atleast Nietzschean, position, Rorty ultimately takes a stand consonant with Ricoeur's desire to rescue speculative discourse from the unruliness of metaphor. Considering Rorty's celebration of Freud in an article on "The Contingency of Selfhood," 3 his failure to consider the role of unconscious associations and overdetermination in the writing and reading of texts is surprising. Dead or alive, a metaphor brings with it a host ofpersonal and public, conscious and unconscious, new and traditional associations that become juxtaposed against a similar number of associations connected with the signifying chain into which the metaphor has been inserted. In... (shrink)

I will argue that those thinking about conceptual engineering should think more about ways of believing. When we talk about what someone “believes”, we could be talking about how they are inclined to act, or what they have put forth as their position on a matter, or what gives rise to a feeling of endorsement when they reflect on the matter. If we further recognize that the contents of our beliefs are at least sometimes framed in certain concepts and that (...) projects of conceptual engineering at least sometimes aim to change our beliefs by changing the concepts they are framed in, the question arises: which beliefs does conceptual engineering target? Is it always “belief” in the same sense? I will argue that it is not, using examples from feminist and mainstream metaphysics. Suppose that revisionary ontologists call on us to eliminate the non-joint-carving concept TABLE from our beliefs about the world. They then plausibly have in mind only “belief” in the sense of practically detached reflective assent: they want the concept eliminated from the content of such assent. On the other hand, when feminist metaphysicians of gender call on us to ameliorate the ethically problematic concept WOMAN, they target our “beliefs” in a sense that encompasses both the content of our everyday observations and experiences and what might be called practically engaged reflective assent; but they do not target the practically detached assent. (shrink)

Digital spaces are saturated with metaphor: we have pages, sites, mice, and windows. Yet, in the world of digital textuality, these metaphors no longer function as we might expect. Martin Paul Eve calls attention to the digital-textual metaphors that condition our experience of digital space, and traces their history as they interact with physical cultures. Eve posits that digital-textual metaphors move through three life phases. Initially they are descriptive. Then they encounter a moment of fracture or rupture. Finally, they go (...) on to have a prescriptive life of their own that conditions future possibilities for our text environments - even when the metaphors have become untethered from their original intent. Why is "whitespace" white? Was the digital page always a foregone conclusion? Over a series of theses, Eve addresses these and other questions in order to understand the moments when digital-textual metaphors break and to show us how it is that our textual softwares become locked into paradigms that no longer make sense. Contributing to book history, literary studies, new media studies, and material textual studies, Theses on the Metaphors of Digital-Textual History provides generative insights into the metaphors that define our digital worlds. (shrink)

Like Joan Didion's The Year of Magical Thinking, an extraordinarily moving and engaging look at loss and death. Eve Joseph is an award-winning poet who worked for twenty years as a palliative care counselor in a hospice. When she was a young girl, she lost a much older brother, and her experience as a grown woman helping others face death, dying, and grief opens the path for her to recollect and understand his loss in a way she could not as (...) a child. In the Slender Margin is an insider's look at an experience that awaits us all, and that is at once deeply fascinating, frightening, and in modern society shunned. The book is an intimate invitation to consider death and our response to it without fear or morbidity, but rather with wonder and a curious mind. Writing with a poet's precise language and in short meditative chapters leavened with insight, warmth, and occasional humor, Joseph cites her hospice experience as well as the writings of others across generations--from the realms of mythology, psychology, science, religion, history, and literature--to illuminate the many facets of dying and death. Offering examples from cultural traditions, practices, and beliefs from around the world, her book is at once an exploration of the unknowable and a very humane journey through the land of grief. (shrink)

Surprisingly, when Laurence Sterne’s Yorick sets his head toward Dover, it is with no developed motive of connoisseurship or curiosity: the gentleman dandy ups with his portmanteau at the merest glance of “civil triumph” from a male servant. Perhaps we are in the world of P. G. Wodehouse, with a gentleman’s gentleman who happens, like Jeeves, to be the embodiment of all the prescriptive and opportunistic shrewdness necessary to maintain his master’s innocent privileges—but it is impossible to tell; the servant (...) utters his five words, glances his glance, and disappears from the novel. The prestige that has lent force to his misprision—or is it a sneer?—seems to belong not to a particular personality but to a position, a function , a bond between gentleman and gentleman’s gentleman that, throughout this novel, makes up in affective and class significance what it lacks in utilitarian sense. Yorick’s bond to another valet is the most sustained and one of the fondest in the novel; and, for most of the novel, the bond is articulated through various forms of the conquest and exchange of women.In the discussion ahead, I will be using the “exchange of women” paradigm taken from Claude Lévi-Strauss and, for example, René Girard and Gayle Rubin, to focus on the changing meanings of the bonds between men in a seventeenth-century play and an eighteenth-century novel.1 These discussions are part of a book-length study of what I am calling “male homosocial desire”—the whole spectrum of bonds between men, including friendship, mentorship, rivalry, institutional subordination, homosexual genitality, and economic exchange—within which the various forms of the traffic in women take place. Eve Kosofsky Sedgwick is associate professor of English at Amherst College. She is the author of Between Men: English Literature and Male Homosocial Desire. (shrink)

Many things are frightening in the process by which people identify against and resist oppressions. One of the worst is how easy it is for people to be made to feel, by some intervention from another, that their own identity and their standing from which to resist that oppression have been foreclosed or annihilated: their voices delegitimated, the authority of their grounding in an indispensable identity threatened with erasure. Anyone who has worked in feminist groups, for instance, knows the moment (...) when a woman or group of women announce that they have sat silent through a discussion, not because they had nothing to say, but because they felt silenced, felt radically denegated by some act or speech or some perceived dynamic of the group. These announcements make shifty moments in the power relations of a group. They bring to the surface, by rupturing it, how far from impartial or inclusive is the normal, “neutral” decorum of conversational exchange, and how far from detached are the needs and dreads that people have invested in it. The fabric of trust that gives a nominally egalitarian texture to activist interactions is—it is always shocking to have once more to learn—a fragile one that a multitude of unacknowledged presumptions can suddenly leave gaping. Eve Kosofsky Sedgwick is professor of English at Duke University. She is the author of Between Men: English Literature and Male Homosocial Desire and the forthcoming Epistemology of the Closet. Her most recent contribution to Critical Inquiry is “Sexualism and the Citizen of the World: Wycherley, Sterne, and Male Homosocial Desire”. (shrink)

This case study of the feminist drag troupe the Disposable Boy Toys examines the relationship between drag and gender identity. Drawing on multiple methods, the author explores the range of gender identities that emerged through participation in DBT. Members saw DBT as the central catalyst for their own identity shifts. The author suggests that these identity transformations occurred through four collective mechanisms: imaginative possibility, information and resources, opportunities for enactment, and social support. The author finds that DBT served as an (...) identity incubator in which participants were able and encouraged to interrogate, play with, and sometimes adopt new gender identities. The author concludes that context is critical in understanding the meaning and importance of drag. Performing gender in this politicized, feminist context shaped the gender identities of the troupe's members in fundamental and varied ways, suggesting that oppositional communities can be an important venue for identity work. (shrink)

Introduction -- The perceptual part of the soul -- Human perception -- The duality of the human soul -- Phronesis -- Conclusion.

Prisoners are legally categorized as a vulnerable group for the purposes of medical research, but their vulnerability is not limited to the research context. Prisoner-patients may experience lower standards of care, fewer options for treatment, violations of privacy, and the use of inappropriate surrogates as a result of their status. This case study highlights some of the ways in which a prisoner-patient’s vulnerable status impacted the care he received. The article argues the following: (1) Prisoner-patients are entitled to the same (...) quality of care as all other patients, and healthcare providers should be vigilant to ensure that the stigma of incarceration does not influence care decisions. (2) Options for treatment should reflect what is most medically appropriate in the hospital or other healthcare setting, even when not all treatments would be available in the correctional setting. (3) The presence of guards at the bedside requires that additional measures be taken to protect the privacy and confidentiality of prisoner-patients. (4) When endof-life decisions must be made for an incapacitated patient, prison physicians are not well placed to act as surrogate decision makers, which heightens the obligations of the healthcare professionals in the hospital to ensure an ethically supportable process and outcome. Therefore, healthcare professionals should provide extra protection for those prisoner-patients who do not have decision-making capacity, by utilizing a robust process for decision making such as those used for incapacitated patients without surrogates, rather than relying solely on prison physicians as surrogates. (shrink)

The debate between Bloor and Latour is based on a fundamental misunderstanding due to too narrow a view of what Bloor calls ‘the field’. The boundaries of this ‘field’ are not defined by the sociological analysis of the content of science: SSK and Latour do not share the same object of study. Latour's approach marks a shift from the social determinants of scientific knowledge to the ontological labour performed by scientific activity. The research on the science/society interface has generated two (...) approaches. Some works tackle the social factors which determine science. Their object is society in science. Other works address the social role of science. Their object of study is science in society. The difference in the way SSK and Latour look at science is an incarnation of this division. A re-conceptualization of ‘the field’ based on the acknowledgement of these two objects is perhaps the only way to allow for a diversity of approaches in the study of the science/society interface. (shrink)

The author takes a collection of essays on concepts and approaches in evolutionary epistemology as the occasion for a critical discussion of the limits and achievements of evolutionary epistemology as well as of certain philosophical objections to the very project itself. She comes to the conclusion that evolutionary epistemology, even if it cannot explain cognition itself, can nevertheless shed light on the complex phenomenon of cognition by demonstrating the presence of traces of our evolutionary past in cognition. Modern research into (...) the structure and functioning of the brain supports this conclusion. The author argues that the questions which evolutionary epistemology can legitimately pose and answer are such that it is not in competition with traditional epistemology. For this reason she suggests that this research program be renamed "evolutionäre Informationstheorie", in the hope that its aims will become clearer to proponents as well as opponents. In the final section the author discusses the possibility that an evolutionary approach might explain the fact that human beings are less and less capable of dealing with the complexity of the world they have created. (shrink)

Quand Bruno Latour introduit le « monde commun » dans son oeuvre à la fin des années 1990, ce syntagme est déjà fort connu en théorie politique où il circule largement depuis la parution en 1958 du magnum opus d’Hannah Arendt The Human Condition. Or, Latour ne se réclame pas d’Arendt quand il traite du monde commun et, s’il la mentionne à l’occasion, c’est toujours pour s’en distancer. En analysant les conceptualisations respectives de Latour et d’Arendt, le présent article vise (...) à montrer qu’il existe bien un monde commun entre ces deux penseurs que tout semble éloigner.When Bruno Latour introduces the “common world” in his work at the end of the 1990s, this phrase is already well known in political theory thanks to the 1958 publication of Hannah Arendt’s magnum opus The Human Condition. Strangely enough, when he addresses the common world Latour does not claim to be a follower. If he mentions Arendt from time to time, it is always to distance himself from her. Through the analysis of the respective conceptualisations of Latour and Arendt, the present article aims to show that a common world does exist between these two authors who seemingly stand so far apart from one another. (shrink)

Does conceptual engineering as a philosophical method deserve all the attention that it has been getting recently? The important philosophical questions, one might say, are about the world, not about what our concepts are or should be like. This paper fleshes out one way in which conceptual engineering can contribute to philosophical progress. The suspicion that conceptual engineering is getting too much attention presupposes that it is important to distribute our philosophical attention well (for example, conceptual engineering should not get (...) more than its fair share). The paper’s defense of conceptual engineering builds on that assumption. Conceptual engineering, it argues, is a way of configuring philosophers’ patterns of attention for the better: it serves attentional progress in philosophy. (shrink)

Reading literature with the aid of computational techniques is controversial. For some, digital approaches apparently fetishize the curation of textual archives, lack interpretative rigor, and are thoroughly ’neoliberal’ in their pursuit of Silicon Valley-esque software-tool production. For others, the potential benefits of amplifying reading-labor-power through non-consumptive use of book corpora fulfills the dreams of early twentieth-century Russian formalism and yields new, distant ways in which we can consider textual pattern-making (Jockers; Moretti, Distant Reading; Moretti...

This article focuses on the theological journeying of women ordinands in the Church of England, who have had to negotiate their belonging in the ‘pathway’ to Priesthood in ordination training. Attention is given to the extent to which the personhood of women is enabled to truly flourish in a theological education system that is dominated by men and predominantly patriarchal and Western theologising. It suggests that a gendered politics of belonging has been used and maintained through the socio-religious construct of (...) ‘shame’ in order to maintain the boundaries of belonging within the formation process, and therefore calls for an en-gendered ‘pathway to the priesthood’. This is exemplified in a re-reading of the bleeding woman who dares to challenge the hegemonies of patriarchy and purity by touching the cloak of Christ in Luke 8:40-48. This research is part of an ongoing project with Common Awards at Durham University that explores barriers to belonging in theological education for those in training for ordination. It has therefore received ethical approval for interviews and participant observations. (shrink)

By disentangling the history of free indirect style from the history of the novel, we can see the narratorial complexity of prose fiction at a revealingly early stage, when the channeling of other minds and other experiences seemed less like a generic affordance than a problem of etiquette, moral judgment, and simple intelligibility. Lacking novelistic conventions (for example, quotation marks), the Elizabethan writer George Gascoigne experimented with a range of techniques for representing the voices and thoughts of his characters. In (...) The Adventures of Master F.J. (1573), he does not consistently or clearly mark particular expressions as belonging to either character or narrator. The effect of this is a wandering or mobile point of view, a protoform of free indirect style—not as a deliberate aesthetic effect but rather as the product of experimentation with a not yet fully articulated set of formal conventions. Gascoigne’s use of this emergent free indirect style centers on a key scene of sexual assault and its aftermath. This, I argue, is no accident as sexual consent foregrounds with particular urgency the moral stakes of attributing thoughts, desires, and motives to other people. In the early days of prose fiction, Master F.J. thus shows us the potentially disturbing entanglement between sexual nonconsent and one of the central tools and methods of literary narrative: its practice of channeling the voices of others. (shrink)