Welfare science has built its foundations on veterinary medicine and thus measures of health. Since bottlenose dolphins (Tursiops truncatus) tend to mask symptoms of poor health, management in captivity would benefit from advanced understanding on the links between health and behavioural parameters, and few studies exist on the topic. In this study, four representative behavioural and health measures were chosen: health status (as qualified by veterinarians), percentage of daily food eaten, occurrences of new rake marks (proxy measure of social activity), (...) and willingness to participate (WtP) in Positive Reinforcement Training sessions as qualitatively measured by their caretakers. These data were collected multiple times a day, every day over the course of a year from a multi-facility, large sample size (ndolphins= 51), allowing powerful analyses of the relationships between measures. First, it was found that dolphins with a higher WtP score also had a significantly better health status, ate a higher percentage of their daily food, and a lower occurrence of new rake marks. In addition, the WtP score was significantly lower up to 3 days before the weekly veterinary diagnosis of a decrease in health state; the percentage of daily food eaten and new rake mark measures did not show any significant change before such a diagnosis. These results suggest that WtP in training sessions is a potential behavioural measure of dolphin welfare, and an indicator of early changes in the dolphins’ health state. We therefore suggest measurement of WtP as a more practical and non-invasive tool to support veterinary care and general management. More work needs to be conducted to elucidate the influence of social behaviour on health, and to identify other potential welfare indicators, but this long-term study has shown that qualitative measures can be both practical and valid when assessing dolphin welfare. (shrink)

Now in its fourth edition, Rational Diagnosis and Treatment: Evidence-Based Clinical Decision - Making is a unique book to look at evidence-based medicine and the difficulty of applying evidence from group studies to individual patients._ The book analyses the successive stages of the decision process and deals with topics such as the examination of the patient,_the reliability of clinical data, the logic of diagnosis, the fallacies of uncontrolled therapeutic experience and the need for randomised clinical trials and meta-analyses. It is (...) the main theme of the book that, whenever possible, clinical decisions must be based on the evidence from clinical research, but the authors also explain the pitfalls of such research and the problems involved in applying evidence from groups of patients to the individual patient._ For this new edition, the sections on placebo and meta-analysis and on alternative medicine have been thoroughly updated, and there is more focus on insufficient reporting of harms of interventions. The sections on different research designs describe advantages and limitations, and the increased medicalisation and the effects of cancer screening on health people are noted. A section on academic freedom when clinicians collaborate with industry and ghost authors is added._ This essential reference work integrates the science and statistical approach of evidence-based medicine with the art and humanism of medical practice; distinguishing between data, sets of data, knowledge and wisdom, and their application. Such an intellectually challenging book is ideal for both medical students and doctors who require theoretical and practical clinical skills to help ensure that they apply theory in practice. (shrink)

After briefly reviewing the standard set-theoretic resolutions of the Burali-Forti paradox, we examine how the paradox arises in set theory formalized with plural quantifiers. A significant choice emerges between the desirable unrestricted availability of ordinals to represent well-orderings and the sensibility of attempting to refer to ‘absolutely all ordinals’ or ‘absolutely all well-orderings’. This choice is obscured by standard set theories, which rely on type distinctions which are obliterated in the setting with plurals. Zermelo's attempt ( 1930 ) to secure (...) ordinal representability of arbitrary well-orderings through relativization of quantification to set-theoretic models is reviewed and found wanting. The natural modal-structural recasting provides, it is claimed, a good repair. (shrink)

This book, published in 1986, addresses questions concerned with a central normative principle in contemporary assessments of economic policies and systems. What does 'consumer sovereignty' mean? Is consumer sovereignty an appropriate principle for the optimization and evaluation of the design and performance of economic policies, institutions and systems? If not, what is a more appropriate principle? The author argues that the conception of consumer sovereignty has to be broadened so that it is not limited to the market mechanism but includes (...) environmental, work and social preferences. However, even this version runs into serious difficulties as the principle of consumer sovereignty still relies on too subjectivist a conception of the interests of individuals to be suitable for the evaluation of economic institutions. An alternative basis for such evaluation is 'human interests' that are not contingent on particular economic systems, After considering various possibilities, a basic-needs approach is proposed and its use in economic evaluation illustrated. (shrink)

Studies of coexistence are based ultimately on the assumption that competitive exclusion is a general and accredited phenomenon in nature. However, the ecological and evolutionary impact of interspecific competition is of questionable significance. Review of three reputed examples of competitive exclusion in the field (Aphytis wasps, red and grey squirrels, and triclads) demonstrates that the widely-accepted competition-based interpretations are unlikely, that alternative explanations are overlooked, and that all other reported cases need critical reinvestigation. Although interspecific competition does undoubtedly occur, the (...) evidence suggests it is usually too weak and intermittent a force to achieve competitive exclusion or any other ecologically-significant result, except perhaps rarely and on a minor scale. Coexistence and community structure are therefore not ecological conditions to be especially accounted for, especially since their inherently comparative methods generate information that is largely superficial. Alternative questions that relate directly to species, the units of diversity, are discussed and they emphasize the primary habitat requirements of species, which are fixed during speciation. Neither the comparative approach of coexistence studies, nor the investigation of pattern is likely to be profitable, since the acquisition of species-specific characteristics during speciation requires historical research. At least one alternative theory of ecology, based on the close adaptation of organisms to the environment, is available. (shrink)

Three basic political positions on embryo research will be identified as libertarian, conservative, and social-democratic. The Human Embryo Research Panel will be regarded as an expression of the social-democratic position. A taxonomy of the ethical issues addressed by the Panel will then be developed at the juncture of political and ethical modes of reflection. Among the arguments considered will be those for the separability of the abortion and embryo research debates; arguments against the possibility of the preembryo being a person, (...) especially arguments associated with totipotency and the significance of the primitive streak; and the various reasons for regulating embryo research, including those associated with respect for the preembryo, the protection of traditional views of human procreation, and the prevention of commercialization. (shrink)

Some earlier remarks Michael Dummett made on Gödel’s theorem have recently inspired attempts to formulate an alternative to the standard demonstration of the truth of the Gödel sentence. The idea underlying the non-standard approach is to treat the Gödel sentence as an ordinary arithmetical one. But the Gödel sentence is of a very specific nature. Consequently, the non-standard arguments are conceptually mistaken. In this paper, both the faulty arguments themselves and the general reasons underlying their failure are analysed. The analysis (...) reveals the true nature of the epistemological relation between the Gödel sentence and its numerical instances. (shrink)

Outlines a method of solving mathematical problems for teachers and students based upon the four steps of understanding the problem, devising a plan, carrying out the plan, and checking the results.

In his 1841-2 Berlin lectures, Schelling critiques German idealism’s negative method of regressing from existence to its first principle, which is supposed to be intelligible without remainder. He sees existence as precisely its remainder since there could be nothing that exists. To solve this, Schelling enlists the positive method of progressing from the fact of existence to a proof of this principle’s reality. Since this proof faces the absurdity that there is anything rather than nothing, he concludes that this fact’s (...) constitution and this principle’s proof are mutually dependent, non-dischargeable tasks. I trace this reciprocal relation to one Kant establishes between the constitutive categories of experience and the experience that proves their applicability and argue that it adheres to Kant’s threefold criterion of proof. I do so by uncovering the Maimonian skeptical motivation—specifically, the need to answer what I call the question quid indicii—behind the qualified return to Kant on which Schelling’s critique of idealism relies. (shrink)

Psychiatry's relation to the rest of medicine is ambivalent. Its legitimacy as a specialty is often conceived as being closely linked to its fidelity to the fundamental paradigms of medicine, especially the centrality of diagnosis and the association of diagnosis with treatment indications. However, as Gagné-Julien notes, a major impetus behind the quest for a solution to the demarcation problem in psychiatry is "growing concerns regarding over-medicalization". Although it could appear that these two considerations point in opposite directions, both arguably (...) would be served by what Gagné-Julien labels "a satisfying definition" of mental disorder. Such a... (shrink)

Este ensayo presenta una visión de conjunto del modo en el cual el «giro» (Kehre) hacia el pensamiento ontohistórico, a medidados de los años ’30, impacta sobre la concepción aleteiológica que, siguiendo a E. Lask y E. Husserl, Heidegger elabora desde comienzos de los años ‘20 hasta Sein und Zeit. Sobre esa base, se ofrece también un intento de caracterización de la reformulación eventualista-kairológica de la aleteiología presentada en Beiträge zur Philosophie. La caracterización propuesta se lleva a cabo con arreglo (...) a la distinción entre un nivel metahistórico de consideración, que corresponde al intento de pensar el seren su verdad en términos de la noción de «acontecimiento» (Ereignis), y un nivel propiamente histórico de consideración, que corresponde a la «hermenéutica de los dos comienzos». El pensar que medita históricamente el ser en su verdad sólo puede ser fiel a la intrínseca movilidad del ser mismo, si se ejerce en y desde la quietud de la contención, como temple animímico fundamental. (shrink)

The theme of the paper is defined by the relevance and insufficient scientific elaboration of the concept of dental tourism in Russia on the basis of deep, comprehensive and conceptually oriented research. The article presents the analytical review of foreign literature in the field of dental tourism. The authors consider various approaches to the definition of the conceptof dental tourism. Scientific developments which are devoted to the dental tourism have not been conducted in our country yet. Mainly, the scientific developments (...) in the sphere of dental tourism are conducted for advertising purposes. The authors points to the possibility and necessity of this study within the framework of sociology of medicine which has the methodological and operational basis for achieving the planned result. (shrink)

For the last 25 years, since publication of his Logical Studies, Professor Von Wright has steadily explored the field of philosophical logic. The concept of negation, logical paradoxes, the puzzles connected with evidence and probability in confirmation theory, the interrelatedness of the ideas of time and change, and the clarification of the structure of temporal and spatial orderings are among the many areas he has profitably investigated.

Like all research, embryo research can take a variety of forms, some posing substantially more risks to persons than others. Savulescu et al argue persuasively that regulatory regimes specially designed for sensitive embryo research should differentiate between person-affecting and non-person-affecting embryo research, with substantial scrutiny only warranted for the former.1 Yet if we find Savulescu et al ’s argument persuasive, what practical implications would it have? In this commentary, we focus in particular on how such an argument might apply in (...) Singapore, one of the jurisdictions with special regulations for embryo research. We will summarise the way in which approval for oocyte and embryonic research operates in Singapore, and suggest that Savulesc et al ’s distinction requires specification to be useful in such contexts. We propose adopting a risk-stratified framework similar to that employed with Institutional Review Boards. This requires a wider view of risks than the focus by Savulescu et al on future persons. We then illustrate how such a framework would apply in five scenarios discussed in Savulescu et al. Research with embryos and oocytes is regulated in Singapore under the Human Biomedical Research Act.2 Enacted in 2015, this law sets out requirements for consent, IRB review and research oversight. By definition, all research involving gametes and embryos fall within the remit of the Act. Moreover, such research is defined as ‘restricted’; besides the Act, research involving oocytes and embryos is also subject to control under the Human Biomedical Research …. (shrink)

Medical decisions regarding end-of-life care have undergone significant changes in recent decades, driven by changes in both medicine and society. Catholic tradition in medical ethics offers clear guidance in many issues, and a moral framework accessible to those who do not share the same faith as well as to members of its faith community. In some areas, a Catholic perspective can be seen clearly and confidently, such as in teachings on the permissibility of suicide and euthanasia. In others, such as (...) withdrawal of nutrition and hydration, the Church does not yet speak with one voice and has not closed out the discussion. Yet, it is not in the teaching on individual issues that a Catholic moral tradition offers the most help and comfort, but in its account of what it means to lead a life in Christ, and to prepare for a Christian death. As in the problem of pain and suffering, it is the spiritual support more than the ethical guidance that helps both patients and physicians bear the unbearable and fathom the unfathomable. (shrink)

The world is not on track to achieve Agenda 2030—the approach chosen in 2015 by all UN member states to engage multiple stakeholders for the common goal of sustainable development. The creation of the 17 Sustainable Development Goals (SDGs) arguably offered a new take on sustainable development by adopting hybrid and principle-based governance approaches, where public, private, not for profit and knowledge-institutions were invited to engage around achieving common medium-term targets. Cross-sector partnerships and multi-stakeholder engagement for sustainability have consequently taken (...) shape. But the call for collaboration has also come with fundamental challenges to meaningful engagement strategies—when private enterprises try to establish elaborate multi-stakeholder configurations. How can the purpose of businesses be mitigated through multi-stakeholder principle-based partnerships to effectively serve the purpose of a common sustainability agenda? In selecting nine scholarly contributions, this special issue aims at advancing this discourse. To stimulate further progress in business studies, this introductory essay, furthermore, identifies three pathways for research on multi-stakeholder engagement processes in support of the Decade of Action along three coupling lines: multi-sector alignment (relational coupling), operational perception alignment (cognitive coupling) and goal and strategic alignment (material coupling). (shrink)