The need for a framework to justify that a model has sufficient credibility to be used as a basis for internal or external (typically regulatory) decision-making is a primary concern when using modelling and simulation (M&S) in healthcare. This chapter reviews published standards on verification, validation, and uncertainty quantification (VVUQ) as well as regulatory guidance that can be used to establish model credibility in this context, providing a potential starting point for a globally harmonised model credibility framework.

Résumé La collaboration avec une chorégraphe engage une réévaluation du travail de sculpture. Cette interprétation débouche sur des formes nouvelles par l’intermédiaire de sculptures animées qui s’apparentent à des formes de marionnettes.

This book is the first of its kind to offer a new definition of contemporary management. It uses Michel Henry’s philosophy and takes the real, sensitive and pathetic subjectivity of individuals as the starting point of the analysis as opposed to the usual large categories of representations; resources; images; and discourses. This book thus proposes to rethink management by insisting on the dialectic of strength and vulnerability; its power of constraint, imitation and imagination; and finally its framework of action situated (...) in a fourfold concern for the self, for people, for institutions and for the environment. These different notions are useful in order to experience a deeper understanding of management that is free from the obsolescence of the distant recommendations of ancient protomanagement and the outdated and dubious prescriptions of the so-called “scientific management”. (shrink)

This book offers a comparative study of the management of legal pluralism. The authors describe and analyse the way state and non-state legal systems acknowledge legal pluralism - defined as the coexistence of a state and non-state legal systems in the same space in respect of the same subject matter for the same population - and determine its consequences for their own purposes. The book sheds light on the management processes deployed by legal systems in Africa, Canada, Central Europe and (...) the South Pacific, the multitudinous factors circumscribing the action of systems and individuals with respect to legal pluralism, and the effects of management strategies and processes on systems as well as on individuals. The book offers fresh practical and analytical insight on applied legal pluralism, a fast-growing field of scholarship and professional practice. Drawing from a wealth of original empirical data collected in several countries by a multilingual and multidisciplinary team, it provides a thorough account of the intricate patterns of state and non-state practices with respect to legal pluralism. As the book's non-prescriptive approach helps to uncover and evaluate several biases or assumptions on the part of policy makers, scholars and development agencies regarding the nature and the consequences of legal pluralism, it will appeal to a wide range of scholars and practitioners in law, development studies, political science and social sciences. (shrink)

The culmination of three decades of studying and treating survivors of adult onset trauma, _Wounded by Reality_ is the first systematic attempt to differentiate adult onset trauma from childhood trauma, with which it is frequently confused. When catastrophic events overtake adult lives, they often scar the psyche in ways that psychodynamically oriented clinicians struggle to understand. For Ghislaine Boulanger, the enormous challenge of working with these patients is unsurprising. Survivors of major catastrophe, whether a natural disaster, a life-threatening assault, a (...) serious accident, or an act of terrorism, experience a near-fatal disruption of fundamental aspects of self experience. The sense of agency, of affectivity, of bodily integrity, the capacity for self-reflection, the sense of time, and the ability to relate to others - all are called into question. (shrink)

A number of philosophers have recently found it congenial to talk in terms of grounding. Grounding discourse features grounding sentences that are answers to questions about what grounds what. The goal of this article is to explore and defend a counterpart-theoretic interpretation of grounding discourse. We are familiar with David Lewis's applications of the method of counterpart theory to de re modal discourse. Counterpart-theoretic interpretations of de re modal idioms and grounding sentences share similar motivations, mechanisms, and applications. I shall (...) explain my motivations and describe two applications of a counterpart theory for grounding discourse. But, in this article, my main focus is on counterpart-theoretic mechanisms. (shrink)

The analysis of narrative processes and metaphorical language are the topics generally focused on by business ethics researchers interested in the work of Paul Ricœur. Yet his work on political questions also applies to the ethical issues associated with organizations. Ricœur’s ethical enterprise can be expressed as a triad composed of teleological, deontological, and sapiential levels, associating ostensibly opposing positions of Aristotelian and Kantian origin. In this study, I examine politics, economics, and ethics in their dialectic relation as established by (...) Ricœur. Against a vertical, mechanistic, and axiologically neutral vision of management, he opposes the two conceptual pairs of conviction/imagination and ideology/utopia as well as a superior definition of justice associating reciprocal indebtedness and mutual disinterestedness. Through this analysis, it becomes clear that the vertical, hierarchical nature of politics tends to undermine the horizontal interactions necessary to procure just institutions in society. And any business ethic that does not acknowledge political tensions will be mute. What is needed instead is practical wisdom that is developed through interaction, and often through conflict, involving all the different players. (shrink)

‘Have you ever taken sufficient care of yourselves?’ By asking the elite Athenian youth this question, Socrates implies that the liberation of self and the capacity to govern are inseparable. Drawing on the lectures given by Michel Foucault at the Collège de France in 1984 – only recently made available to the public – we show the consequences of the return to this ancient care‐of‐self ethic in the organizational context. After reviewing the contributions made to business ethics by these two (...) philosophers, we propose four phases necessary to the emergence and constitution of a moral subject in organizations: self‐awakening, self‐evaluation, self‐transformation and self‐presentation. We then suggest various managerial practices and behaviour inspired by this philosophical parrhesia embodied by the Greek philosopher wherein the manager should have a personal relationship with his or her own activity. Finally, we discuss implications of our study in the field of business ethics and propose an agenda for future research. (shrink)

This paper is going to discuss, what will be called, ‘The Internet of Bodies’. Our physical and virtual worlds are blending and shifting our understanding of three key areas: (1) our identities are diversifying, as they become hyper-enhanced and multi-sensory; (2) our collaborations are co-created, immersive and connected; (3) our innovations are diverse and inclusive. It is proposed that our bodies have finally become the interface.

It is widely agreed that properties play causal roles: they capture the causal powers of things. But do properties have their causal roles essentially? David Lewis did not think so. He adhered to the doctrine of quidditism, namely the doctrine that the identity of properties is primitive and that they can trade their causal roles. Quidditism is controversial. But Lewis did not see why he should want to reject it. He knew that he could avoid quidditism on the cheap by (...) treating individuals and properties alike in rejecting transworld multilocation of properties and endorsing a counterpart theory for properties. But he did not see why he should want to do so. In this article, I argue that Lewis should have wanted to endorse a counterpart theory for properties in order to reject quidditism. My argument concerns resemblance relations among properties. Another constitutive role of properties is that they capture objective resemblances between their instances. The premises of my argument are intuitive claims about resemblances among some properties that Lewis held on Humean grounds. (shrink)

The influence of Jules Lequier on the development of continental philosophy is currently being revived. Ghislain Deslandes introduces Lequier's thought while highlighting its influence in the development, throughout the twentieth century, including in process thought, pragmatism, existentialism, and phenomenology.

This chapter is concerned with the coextension difficulty for nominalist theories of properties that reject tropes alongside universals. After carefully explaining the coextension difficulty and describing the theories it targets, the chapter describes different solutions to the difficulty. These solutions differ with respect to how much involved they are into a dualist approach to coextension. A dualist approach to a case of coextension consists in agreeing with the realist that the relevant ascriptions of properties are numerically distinct. A monist approach (...) to a case of coextension consists in contending that the relevant ascriptions of properties are identical. In this chapter, I defend a monist approach to cases of coextension that appeals to a counterpart theory for propositions. (shrink)

According to Ghislain Deleplace, Jacques Sapir criticizes economical science for lacking in internal coherence due to the domination of the theory of general balance, that doesn’t take in account the economical reality, in particular the behaviour of individual economical actors, constituting the research programme of the new economy.

Cet article s’intéresse au marché de l’édition scientifique et à son évolution dans le cadre de l’Internet et du développement du libre accès. Il s’attache à montrer la diversité de ce marché en fonction des champs scientifiques, notamment par le type d’éditeurs impliqués, les lectorats concernés, les économies associées. Il met en exergue le nécessaire discernement de ces marchés face aux critiques générales de dysfonctionnement soulignées. Il pointe certains effets contrastés du numérique conduisant à certaines reconfigurations paradoxales. Enfin, la vision (...) prospective sur le devenir de ce marché insiste sur la pluralité des modalités de progression vers le libre accès, le poids de la dimension politique et celui des processus d’évaluation de la recherche. La voie d’un partenariat public-privé est privilégiée au regard de certaines valeurs centrales : indépendance, qualité, accessibilité et pérennité des publications scientifiques.This article investigates the scientific publishing market and how it is being transformed by the Internet and the development of open-access services. We illustrate the diversity of the market in terms of scientific fields, and especially in the types of publishers and readerships concerned, and of the associated economics. In view of the sweeping criticisms of dysfunctional practices illustrated in the article, we alert readers as to the need for discernment among these markets. The article points to a number of contrasting effects of digital publishing that are leading to various paradoxical reconfigurations. Finally, this forward-looking study of the publishing market’s future emphasises the multiple forms of the onward march towards open access and the influence exerted by the political dimension and the research evaluation process. Public-private partnerships are the preferred option to cater for the central values of independence, quality, accessibility and the enduring nature of scientific publications. (shrink)

By deliberately placing ethics under the category of communication, Kierkegaard intended to show that it is like no other science. He distinguished betweendirect communication and indirect communication. Direct communication concerns objectivity and knowledge; indirect communication, on the other hand, has to do with subjectivity (“becoming-subject”). In this paper, the author presents Kierkegaard’s philosophy of communication and ethics with special emphasis on his irony and pseudonymous authorship. He also examines the possibility of a discourse in business ethics, focusing on the educational (...) perspective. He discusses Kierkegaard’s aspects of communication—the communicator, the receiver, and the object—with particular reference to applied ethics. He argues that the Kierkegaardian notion of indirect communication can contribute to renewing business ethics teaching—which in his view is more art than science—in two important ways: (1) when the ethics teacher changes his position in the teacher/learner relationship; and (2) when the relationship between communicator/receiver is strengthened at the expense of the object. (shrink)

Les critiques du Père de Tonquédec ont conduit Bergson à préciser ses raisons d’affirmer la transcendance de Dieu. Suite aux réponses du philosophe, le théologien a renouvelé et déplacé ses critiques. À travers cette discussion, on est amené à penser l’écart posé par Bergson entre Dieu et les élans vitaux. Le philosophe rencontre une réelle difficulté en affirmant à la fois la transcendance et une certaine immanence de Dieu. Surtout, dans ce débat, deux conceptions de la transcendance s’opposent, et chacune (...) soulève des problèmes. Est-ce que l’examen bergsonien de l’expérience mystique a pu lever ces problèmes? Dans cet article, on s’efforce d’apporter une réponse à cette question et d’indiquer les conditions de l’institution d’un dialogue entre philosophie et théologie. (shrink)

I call anti-resemblism the thesis that independently of any contextual specification there is no determinate fact of the matter about the comparative overall similarity of things. Anti-resemblism plays crucial roles in the philosophy of David Lewis. For instance, Lewis has argued that his counterpart theory is anti-essentialist on the grounds that counterpart relations are relations of comparative overall similarity and that anti-resemblism is true. After Lewis committed himself to a form of realism about natural properties he maintained that anti-resemblism is (...) true about the relations of overall similarity that enter his counterpart theory and his analysis of counterfactuals. However, in this article I argue that Lewis’s account of degrees of naturalness for properties combined with his modal realism entails that anti-resemblism is false. The Lewisian must amend Lewis’s system if she aims to benefit from the alleged virtues of anti-resemblism. I consider two ways of amending it, neither of which is a free lunch. (shrink)

Church and Fitch have argued that from the verificationationist thesis “for every proposition, if this proposition is true, then it is possible to know it” we can derive that for every truth there is someone who knows that truth. Moreover, Humberstone has shown that from the latter proposition we can derive that someone knows every truth, hence that there is an omniscient being. In his article “Omnificence”, John Bigelow adapted these arguments in order to argue that from the assumption "every (...) contingent proposition is such that if it is true something brought it about that it is true" we can derive that there is an omnificent being: a being that brings it about that every true contingent proposition is true. In my reply to his article, I show that Bigelow’s argument is flawed because there is some formal property that the knowledge operator has but that the bringing about operator lacks. This is the property of distributing over conjunctions. I explain why what brings it about that some conjunctive proposition is true need not bring it about that its conjuncts are true. (shrink)

This article defends the principle of sufficient reason (PSR) from a simple and direct valid argument according to which PSR implies that there is a truth that explains every truth, namely an omni-explainer. Many proponents of PSR may be willing to bite the bullet and maintain that, if PSR is true, then there is an omni-explainer. I object to this strategy by defending the principle that explanation is irreflexive. Then I argue that proponents of PSR can resist the conclusion that (...) there is an omni-explainer by denying that explanation distributes over conjunction. In the final section, I consider a plausible revision of this assumption. I argue there that, given the revised assumption, PSR seems to yield a striking picture of the explanatory structure of the universe. I explain why the resulting model does not appear utterly implausible to me. (shrink)

This article has two goals: a historical and a speculative one. The historical goal is to offer a coherent account of Spinoza’s view on mereological composition. The speculative goal is to show that Spinoza’s substance monism is distinct from versions of monism that are currently defended in metaphysics and that it deserves the attention of contemporary metaphysicians. Regarding the second goal, two versions of monism are currently defended and discussed in contemporary metaphysics: existence monism according to which there actually exists (...) exactly one concrete entity; and priority monism that is famously defended by Jonathan Schaffer and according to which there exists exactly one fundamental concrete being, the cosmos, and several derivative concrete beings that are the parts of the cosmos. In this article, I argue that substance monism is neither an existence nor a priority monism because, while Spinoza’s monist is committed to the existence of a unique fundamental individual—the substance—and to the existence of several derivative individuals—the bodies or modes of extension—, Spinoza denies that the substance is mereologically complex. Regarding the first goal, the paper solves several interpretative puzzles by arguing that Spinoza distinguishes between three kinds of composition and that his talk of composition between the substance and its modes is by his own light not to be interpreted as literally true. (shrink)

This paper introduces the reader to Meinong's work on the metaphysics of magnitudes and measurement in his Über die Bedeutung des Weber'schen Gesetzes. According to Russell himself, who wrote a review of Meinong's work on Weber's law for Mind, Meinong's theory of magnitudes deeply influenced Russell's theory of quantities in the Principles of Mathematics. The first and longest part of the paper discusses Meinong's analysis of magnitudes. According to Meinong, we must distinguish between divisible and indivisible magnitudes. He argues that (...) relations of distance, or dissimilarity, are indivisible magnitudes that coincide with divisible magnitudes called "stretches". The second part of the paper is concerned with Meinong's account of measurement as a comparison of parts. According to Meinong, since measuring consists in comparing parts only divisible magnitudes are directly measurable. Indivisible magnitudes can only be measured indirectly, by measuring the divisible stretches that coincide with them. (shrink)

Cet article montre, – à partir de l’analyse des chapitres VIII, IX et X du Traité théologico-politique, – que la critique de la Bible entreprise par Spinoza ruine dans ses fondements toute forme d’intégrisme religieux et constitue un plaidoyer pour la liberté de pensée philosophique, ouvrant ainsi un espace pour la tolérance.

Sérendipité et temporalité. Voilà deux termes faits a priori pour s’entendre, mais dont l’association reste pourtant obscure au novice. Sérendipité en particulier, malgré un succès d’estime ces dernières années, n’est pas encore un terme très usité. Il évoque le hasard, bien sûr, mais aussi la sagacité, l’esprit de curiosité, l’agilité, la disponibilité mentale, bref tout ce qui permet de rester à l’affût du neuf et du surprenant. De quoi s’agit-il à l’origine et d’où provient ce terme étrang...

This study provides (1) a reading of the theses of John Macmurray, (2) a comparative phenomenological analysis, and (3) an investigation of the meaning of affectivity within this analysis.

Un temps de crise grave peut devenir un moment de grande espérance. Nous savons aujourd'hui que la civilisation du logos sous laquelle l'Occident vit depuis près de trois mille ans, dans une dialectique constante entre philosophie et christianisme, arrive à un point à la fois d'accomplissement et d'épuisement. Elle avait d'abord donné sa confiance à des explications englobantes. Celles-ci ont trouvé, dans l'Antiquité, leur forme quasi idéale : le logos avait pris alors un tour mystique et débouchait vers un Au-delà (...) de tout, qui n'a laissé indifférent ni l'islam ni le christianisme. Dans la modernité, il s'était organisé de manière parfaitement immanente ou soigneusement historique. A présent, il continue son chemin, mais devant l'épuisement des idées et des constructions qui lui donnaient corps et sens, il ne conserve que son armature essentiellement mathématique, dépouillée de toute réalité, sinon celle du nombre - ce que, dans notre langage actuel, nous appelons le " virtuel ". Nous pouvons recueillir aujourd'hui l'efficacité de ces pensées et pratiques pénétrées de la dynamique du Tout et du Rien. Mais, au point où nous en sommes actuellement, il y a une vraie menace que le Tout bascule vraiment dans le Rien et que nous allions à la catastrophe éthique, humaine, cosmique. Il a manqué sans doute à cette civilisation le respect du Quelque chose : ni tout, ni rien, mais substance, action, relation. Ici Aristote, dans l'Antiquité, et Thomas d'Aquin, au seuil de la modernité, peuvent venir à notre secours et nous aider à retrouver notre épaisseur d'homme, à ne pas fuir le jeu étrange en nous de la matière pénétrée de ce que nous appelons esprit, qui à la fois lui est immanent et la dépasse, à restituer par là un humanisme et une approche non aliénante du divin. Il y a sans doute là un motif d'espérance. Mais ce grand motif d'espérance réside surtout dans le tournant anthropologique contemporain : nous comprenons aujourd'hui que l'homme n'existe pas en réalité sans son frère qui lui parle. A la lumière de cette conversation essentielle, on doit pouvoir définir un humanisme et une politique ; une perspective s'ouvre aussi pour réinterpréter la religion et particulièrement le christianisme. À l'horizon apparaissent le symbole, la relation, la mort et la résurrection, l'amour. (shrink)

Launched in 2007, the American Medical Students Association PharmFree Scorecard is an annual ranking of conflict of interest policies at American medical centres; it focuses on COIs that may occur when medical education seems likely to be influenced by university-industry relationships, especially those with the pharmaceutical and medical device industries. The PharmFree Scorecard has proven influential in stimulating changes in policy regarding the management of COI at American medical institutions, thus it provides a useful jumping off point for reflection on (...) how and why medical education institutions in other countries – and for our purposes, Canada – should pay more attention to the appropriate identification and management of COI. The PharmFree Scorecard methodology examines a diversity of factors and interests that could influence medical education; as such, it is an interesting approach to analysing the COI policies of medical schools. To test its utility or applicability outside the US, we decided to apply the PharmFree Scorecard to the COI policies of the 16 Canadian universities hosting medical schools. Overall, Canadian institutions rank very poorly, especially in ensuring that education and training tools are provided to staff, students and faculty members to enable the identification and management of COI. However, differences between the US and Canadian medical education contexts, e.g., with regards to the governance and funding of universities, limit to some extent the direct applicability of the AMSA ranking. Canadian medical schools – and their host universities – nonetheless have much to learn from insights provided by the AMSA PharmFree Scorecard ranking, although they can and should go further in developing their own COI policies and procedures. (shrink)