We analyzed stable patients’ views regarding synthetic biology in general, the medical application of synthetic biology, and their potential participation in trials of synthetic biology in particular. The aim of the study was to find out whether patients’ views and preferences change after receiving more detailed information about synthetic biology and its clinical applications. The qualitative study was carried out with a purposive sample of 36 stable patients, who suffered from diabetes or gout. Interviews were transcribed verbatim, translated and fully (...) anonymized. Thematic analysis was applied in order to examine stable patients’ attitudes towards synthetic biology, its medical application, and their participation in trials. When patients were asked about synthetic biology in general, most of them were anxious that something uncontrollable could be created. After a concrete example of possible future treatment options, patients started to see synthetic biology in a more positive way. Our study constitutes an important first empirical insight into stable patients’ views on synthetic biology and into the kind of fears triggered by the term “synthetic biology.” Our results show that clear and concrete information can change patients’ initial negative feelings towards synthetic biology. Information should thus be transmitted with great accuracy and transparency in order to reduce irrational fears of patients and to minimize the risk that researchers present facts too positively for the purposes of persuading patients to participate in clinical trials. Potential participants need to be adequately informed in order to be able to autonomously decide whether to participate in human subject research involving synthetic biology. (shrink)

This paper explores the importance of hope as a determining factor for patients to participate in first-in-human trials for synthetic biology therapies. This paper focuses on different aspects of hope in the context of human health and well-being and explores the varieties of hope expressed by patients. The research findings are based on interview data collected from stable gout and diabetes patients. Three concepts of hope have emerged from the interviews: hope as certainty ; hope as reflective uncertainty ; hope (...) as self-therapy. The purpose of the paper is twofold. First, it aims to underline the significance of hope in patients’ medical decision-making, as well as the beneficence of hope for patients’ well-being, and for progress in research. Second, it shows how philosophical investigations—in particular Descartes—explore the phenomenon of hope and provide medical empirical research with profitable insights and tools. (shrink)

Recent climate change statistics attribute over a quarter of carbon emissions to residential energy use in the United Kingdom. To address this, a building standard was introduced to aim to reduce the levels of carbon dioxide emissions and energy consumption. This paper analyzes how such an environmental standard reconfigures the sociotechnological relations and practices of housing professionals that design, construct, and manage social housing. We focus on how actors engage with the standard’s recommendation for incorporating low and zero carbon technologies (...) into new buildings. We identify diverse practices that emerge from these engagements, which, we contend, have significant consequences for the working relationships of professional actors and for renewable energy provision. By being entwined in, and generative of actors’ practices, we argue that the Code becomes part of the sociotechnological relationships and infrastructures that shape energy provision. (shrink)

Many philosophers have suggested that claims of need play a special normative role in ethical thought and talk. But what do such claims mean? What does this special role amount to? Progress on these questions can be made by attending to a puzzle concerning some linguistic differences between two types of 'need' sentence: one where 'need' occurs as a verb, and where it occurs as a noun. I argue that the resources developed to solve the puzzle advance our understanding of (...) the metaphysics of need, the meaning of 'need' sentences, and the function of claims of need in ethical discourse. (shrink)

Shavelson et al. (2023) identify an important problem in their Target article: a significant number of terminally ill patients with impaired motor function are wrongfully excluded from receiving ai...

Aimed at undergraduates, _Contemporary Ethics_ presupposes little or no familiarity with ethics and is written in a clear and engaging style. It provides students with a sympathetic but critical guide to utilitarianism, explaining its different forms and exploring the debates it has spawned. The book leads students through a number of current issues in contemporary ethics that are connected to controversies over and within utilitarianism. At the same time, it uses utilitarianism to introduce students to ethics as a subject. In (...) these ways, the book is not only a guide to utilitarianism, but also an introduction to some standard problems of ethics and to several important topics in contemporary ethical theory. (shrink)

En este trabajo se analizan, por una parte, los datos sobre la presencia de las mujeres en los movimientos de derechos de los animales en el estado español; por otro lado, tratamos de encontrar marcos explicativos que aclaren cuál es el vínculo que conecta la sensibilidad feminista con la sensibilidad animalista. Hemos realizado un sondeo sobre el porcentaje de mujeres entre los miembros de las organizaciones animalistas más importantes de España y, con estos resultados, hemos hecho una revisión de los (...) diferentes marcos teóricos que pueden explicar esta significativa orientación de género en la defensa del bienestar animal. Por último, defendemos que hay un vínculo entre la ideología patriarcal y la explotación ecológica, en tanto que ambos comparten la dominación y la opresión de género. En este sentido, la sensibilidad animalista movilizaría sentimientos morales de fraternidad con la naturaleza. (shrink)

The Goddess People of Avalon, a young and flourishing religious community in Glastonbury (South-England), have been defining themselvesprincipally as a revitalization of the prehistoric worship of the Great Goddess. Based on fieldwork data of the author, the article offers an introduction into the religious tradition and ritual praxis of the contemporary Goddess People. Specifically, the analysis focuses on the ritual genre of Sacred Drama with its interpretationof the general and local history of religions. The variety of recursivity (as a reference (...) to the past), which this ritual genre expresses, is examined within an analytical frame that has been developed for different forms of ritual dynamics. Particularly, the analytical concepts ritual transfer, adaptation, invention and ritual design are discussed. Within the lastyears, a change in the self-image and legitimizing strategies of the Goddess People has occurred: Whereas in their nascent years, they understood themselves as a reactualization of primordial spirituality, they tend to see themselvescurrently more as a newreligious tradition, inventing their rituals creatively and confidently. The article argues for the use of the analytical concept ritual design to describe this aspect of ritual dynamics. Thus, instead of evaluating the degree of originality of rituals from an academic point of view, the legitimizing strategiesof religious agents come to the fore. (shrink)

The series of 'trolley' examples issue a challenge to moral principles based on intentions, since it seems that these give the wrong answers in two important cases: 'Fat Man', where they seem to say that it is permissible to push someone in front of a trolley to save others, and 'Loop', where they seem to say that it is wrong to divert a trolley towards a single person whose body will stop it and save others. I reply, first, that there (...) is a parallel between the wrongful intention to mutilate in 'Transplant', where one person's vital organs are removed to save others' lives, and the intention to assault in Fat Man. Secondly, I defend Frances Kamm's view that in Loop one can divert the trolley towards the one without an intention to kill or assault, since good potential side-effects can be taken into account in deciding what to do, without their becoming intentions. (shrink)

In the first part of this article, we show that, contrary to the Gricean tradition, inter-clausal and is not semantically equivalent to logical conjunction and, contrary to temporal approaches such as Bar-Levand Palacas 1980, it is not temporallyloaded. We then explore a commonsenseidea – namely that while sentence juxtaposition might be interpreted either as discourse coordination or subordination, and indicates coordination. SDRT already includes notions of coordinating and subordinating discourse relations (cf. Lascarides and Asher 1993, Asher 1993), and the meaning (...) of and is related to this distinction. Similar distinctions that play a crucial role in anaphora resolution have also appeared in AI – cf. Scha and Polanyi 1988, or Webber 1991. However, this discourse-structure-based distinction has not been well defined yet, and our approach provides independent motivation for it. This paper argues that the semantics of and includes a notion of coordination expressed as the requirement of a Coordinated Discourse Topic (CDT).CDT characterizes aclass of discourse relations, among which are Narration and Result.Once the basic semanticcontribution of and is isolated, effects related to its presence such as changes in temporal structure, blocking of a Discourse Relation, or conditional meanings are shown to follow from the defeasiblearchitecture set up by SDRT. (shrink)

Three studies are presented to validate the Spanish version of Oliver and Raney’s eudaimonic and hedonic motivations scale. In Study 1, 132 university students watched a dramatic film, filling out the scales to evaluate motivations regarding cinema consumption and reception processes. Eudaimonic motivation was associated with deeper cognitive processes during the reception and stronger identification with the protagonist. Study 2 evaluated the test-retest reliability of the eudaimonic and hedonic motivations scale. In Study 3, statistically significant age differences were observed in (...) hedonic and eudaimonic motivations. Furthermore, convergent correlations were detected between hedonic and eudaimonic motivations and preferences of different film genres. These results allow us to conclude that the Spanish version of the hedonic and eudaimonic motivations scale presents adequate psychometric properties, thus being convergent with those obtained by Oliver and Raney. (shrink)

COVID-19 has truly affected most of the world over the past many months, perhaps more than any other event in recent history. In the wake of this pandemic are patients, family members, and various types of care providers, all of whom share different levels of moral distress. Moral conflict occurs in disputes when individuals or groups have differences over, or are unable to translate to each other, deeply held beliefs, knowledge, and values. Such conflicts can seriously affect healthcare providers and (...) cause distress during disastrous situations such as pandemics when medical and human resources are stretched to the point of exhaustion. In the current pandemic, most hospitals and healthcare institutions in the United States have not allowed visitors to come to the hospitals to see their family or loved ones, even when the patient is dying. The moral conflict and moral distress among care providers when they see their patients dying alone can be unbearable and lead to ongoing grief and sadness. This paper will explore the concepts of moral distress and conflict among hospital staff and how a system-wide provider wellness programme can make a difference in healing and health. (shrink)

Digital media seem to be marked by process. The digital image itself is produced by software processes and the constant flux of code. Further this, interaction with digital systems involves a constant process by which a so-called 'user' comes into contact with various machinic occasions. It seems that in light of these processes it is impossible to maintain an aesthetic or media theory that pictures a self-contained and psychologised subject interacting with a static and inert object. How then can we (...) begin to think about digital aesthetics through a process philosophy rather than the traditional and reductive subject/object distinction found in so much aesthetic theory? This paper seeks to address this problem by enacting Alfred Whitehead's process philosophy, informed by Gilles Deleuze, Isabelle Stengers and Steve Shaviro and work it through several examples of recent manifestations of interactive media art, including work by Martin Wattenberg, Dennis Del Favero, Jeffrey Shaw and Peter Weibel. I work Whitehead's process philosophy through these artworks to illustrate the performative nature of software processes and the manner in which these processes affect the aesthetics of interaction. I also use these works to illustrate a concept of interaction that privileges process and events rather than a concept that focuses upon an individual human user. In this paper I propose to view the 'user' as a set of occasions – as a particular condition that is produced by various user-initiated actions – rather than an enduring subject that is able to distance herself from the object of aesthetic contemplation. By doing this I move toward a theory in which user-occasions, machine-occasions and their interpenetration actualise the aesthetics of media art. Whitehead allows me to think outside of the binary oppositions that divide the world into knower/known or subject/object relationships. Throughout the argument I unpack Whiteheadian concepts such as actual entities, the unison of immediate becoming and, in general, the primacy of the event, bringing these concepts to bear on individual case studies of interactive media art. Whitehead's general thesis is that materiality and permanence are created by a continual process. Viewing the digital encounter through this theoretical framework I position the aesthetic experience of interaction as that which emerges from the fluctuations of process. The event of interaction is a necessarily hybrid process in which human occasions become supplemented by technology and the aesthetic event becomes innately coupled to the processes of the machine. In this paper I am not interested in any notion of consciousness or a psychologised human 'user', rather I am interested in a particular condition that takes place as user-initiated processes work with machine-initiated processes. This is because, for Whitehead, process comes before consciousness; it is the process of actual entities that prompt the consciousness into being. In this paper I thus propose interaction with digital systems as the commingling of contemporary actual occasions, shifting emphasis from a conscious human user and instead focusing on the process of the encounter that precedes this conscious experience. (shrink)

Like many humans in the wake of genocide and war, most wildlife today has sustained trauma. High rates of mortality, habitat destruction, and social breakdown precipitated by human actions are unprecedented in history. Elephants are one of many species dramatically affected by violence. Although elephant communities have processes, rituals, and social structures for responding to trauma—grieving, mourning, and socialization—the scale, nature, and magnitude of human violence have disrupted their ability to use these practices. Absent the cultural, carrier groups who traditionally (...) lead and teach these healing practices, humans must assume the role. Trauma theory has brought attention to victims' severe, sustained psychological damage. Looking through the lens of trauma theory provides a better understanding of how systematic violence has affected individuals and groups and how the pervasive nature of traumatic events affects human-nonhuman animal relationships. The framing of recent trauma theory compels conservationists to create new relationships—neither anthropocentric nor powerbased—with nonhuman animals. The David Sheldrick Wildlife Trust, Kenya, shows how humans, taking on the role of interspecies witness, bring orphan elephants back to health and help re-build elephant communities shattered by genocide. (shrink)

Originally delivered at a conference of Marxist philosophers in China, this article examines some links, and some tensions, between business ethics and the traditional concerns of Marxism. After discussing the emergence of business ethics as an academic discipline, it explores and attempts to answer two Marxist objections that might be brought against the enterprise of business ethics. The first is that business ethics is impossible because capitalism itself tends to produce greedy, overreaching, and unethical business behavior. The second is that (...) business ethics is irrelevant because focusing on the moral or immoral conduct of individual firms or businesspeople distracts one’s attention from the systemic vices of capitalism. I argue, to the contrary, that, far from being impossible, business requires and indeed presupposes ethics and that for those who share Marx’s hope for a better society, nothing could be more relevant than engaging the debate over corporate social responsibility. In line with this, the article concludes by sketching some considerations favoring corporations’ adopting a broader view of their social and moral responsibilities, one that encompasses more than the pursuit of profit. (shrink)

In this article, we examine the role of several consumers’ cognitive and psychographic traits in their perceptions of retailers’ deceptive practices and the different effects on perceived deception associated with online vis-à-vis in-store shopping. Building on theoretical models of persuasion in consumer behavior, we hypothesize that the antecedents of perceived deception in traditional settings are the same as those on the Internet, while the intensity of the impact of these antecedents differs between the online and the offline environment. Results suggest (...) that the effects of individual’s cognitive traits and risk aversion on perceived deception are more relevant when consumers shop online than when they purchase from traditional stores. Conversely, psychographic traits play a more important role in explaining perceived deception in the traditional shopping context as compared to the online channel. Several theoretical and managerial implications are derived from these findings. (shrink)

En este artículo, la autora parte del libro "Las enseñanzas de Don Juan: una forma yaqui de conocimiento", de Carlos Castaneda (1974), que forma parte de una trilogía que el autor escribió sobre la tradición y la sociedad de los brujos de México. Sin embargo, este texto puede ser leído por sí so.

The social trackways theory is centered on the remarkable 3.66 mya Laetoli Fossilized Trackways, for they incontrovertibly reveal our ancestors were already obligate bipeds with very human-like feet, and were intentionally stepping in other band members’ footprints to maintain safe footing. Trackways are unique among natural sign systems in possessing a depictive narratively generative structure, somewhat like the symbolic sign systems of gestural languages. Therefore, due to daily embodied reiteration of their own and other band member’s old footprints, both for (...) bipedal safety and as recognizable wayfinding markers for socio-ecological navigation, incrementally our Mid-Pliocene ancestors began to acquire a cognitive capacity for episodic personal memories and episodic future simulations. They began mentally representing themselves as intentional agents continuously travelling from the past into the future. This spatially and temporally self-projecting awareness manifested itself as extra theory of mind and mental space-and-time-travel capacities, which increasingly enabled intentional or conscious, top-down executive adjustment of past behaviors for the sake of achieving better ways of doing things in the future. Future-directed behavioral and cultural adaptations began to increase fitness in all domains, thus creating powerful selective feedback for further entrenchment. Here we focus on overtly or consciously intentional exploratory wayfinding and transmission of elsewhere-and-when information, using pragmatic, discursive modes of communication, which enabled far more cooperative and efficient foraging practices. Selection for better communication thus led to intentional trail marking and the earliest emergence of more conventional/symbolic depictive and gestural “protolanguages.”. (shrink)

Non-therapeutic ventilation of potential organ donors would increase the supply of kidneys for transplantation. There are no major ethical objections to it. The means of permitting it are forbidden by laws with an ethical basis. A law permitting it would need an ethical basis. Introducing a third legal method of diagnosing death would be unethical. Expanding the power of the advance directive to permit procedures involving minimal harm would be ethical but not helpful. Extending the power of proxies to permit (...) specific non-therapeutic procedures which caused or risked minimal harm to incompetent patients is the best way forward. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:163 HUME'S THEORY OF MOTIVATION In this paper I shall defend a Humean theory of motivation. But first I should like to examine some of the standard criticisms of this theory and some alternative views that are currently in favour. Both in the Treatise and the Enguiry Hume maintains that reason alone never motivates action but always requires the cooperation of some separate, and separately identifiable desire-factor in order (...) to bring about action. What are Hume's grounds for this view? In the Treatise. Hume writes: 'Tis obvious, that when we have the prospect of pain or pleasure from any object, we feel a consequent emotion of aversion or propensity, and are carry 'd to avoid or embrace what will give us this uneasiness or satisfaction.... 'Tis from the prospect of pleasure or pain that the aversion or propensity arises towards any object.... This passage suggests that the way we (and Hume) know about the presence of the separate desire factor which he claims is always needed to motivate our every purposive action is by being directly aware of some desire-feeling, by introspection, each and every time we act. There is however a familiar objection to this argument: no doubt we sometimes are aware of a feeling of desire when we act, e.g., in cases where we are motivated by strong emotions. But much of the time when we act calmly or casually, after having deliberated 'in a cool hour', or when performing routine and trivial acts, we are not directly aware of any desire-feeling at the time of action. 164 Hume is not unaware of this objection -- in reply to it he invokes his notorious doctrine of the calm passions. He writes: 'Tis natural for one, that does not examine objects with a strict philosophic eye, to imagine, that those actions of the mind are entirely the same, which produce not a different sensation, and are not immediately distinguishable to the feeling and perception. Reason, for instance, exerts itself without producing any sensible emotion; and except in the more sublime disquisitions of philosophy, or in the frivolous subtilities of the schools, scarce ever conveys any pleasure or uneasiness. Hence it proceeds, that every action of the mind, which operates with the same calmness and tranquillity, is confounded with reason by all those, who judge of things from the first view and appearance. Now 'tis certain, there are certain calm desires and tendencies, which, tho' they be real passions, produce little emotion in the mind, and are more known by their effects than by the immediate feeling or sensation. These desires are of two kinds; either certain instincts originally implanted in our natures, such as benevolence and resentment, the love of life, and kindness to children; or the general appetite to good, and aversion to evil, consider 'd merely as such. When any of these passions are calm, and cause no disorder in the soul, they are very readily taken for the determination of reason, and are suppos'd to proceed from the same faculty, with that, which judges of truth and falshood. Their nature and principles have been suppos'd the same, because their sensations are not evidently different. (T 417) The most obvious application of this argument would be to cases of cool, seemingly passionless 165 deliberation: e.g., in the course of planning the family budget I set aside funds for the children's education. A cursory inspection (or recollection) of the contents of my conscious mind at the time of acting would reveal to me some purely rational considerations that I had in mind at the time. I had some thoughts at the time whose contents are (roughly) expressible in such words as "If I don't put aside so much per month over so many years we will never be able to see them all through university." But cursory introspection or recollection would not detect any separately identifiable desire-factor present to my conscious mind at the time. Considered philosophical examination, Hume assures us, will reveal one, a 'calm' one -- in this case calm 'kindness to children'. Less obviously, the calm-passions argument, most naturally applicable to cases of deliberation... (shrink)

ABSTRACT In recent decades poverty has been defined as a relative rather than absolute notion. Those in poverty have been seen as poor relative to a level of income, or social condition, accepted as average or normal for a society. Poverty has been redefined as ‘relative deprivation’. This paper argues, first, that the redefinition of poverty as relative to social norms is a radical departure from the traditional notion of poverty. Secondly, it considers whether such a redefinition gives support to (...) the view that the claims of those in poverty (relative) may be considered as morally equivalent to the claims of those in poverty (absolute). The paper concludes by arguing that the notion of relative poverty is advanced to give support to social and economic policies whose primary aim is equality rather than the relief of poverty. (shrink)

Emerging biotechnology may soon allow the creation of genetically human organs inside animals, with non-human primates and pigs being the best candidate species. This prospect raises the question of whether creating organs in primates in order to then transplant them into humans would be more acceptable than using them for research. In this paper, we examine the validity of the purported moral distinction between primates and other animals, and analyze the ethical acceptability of using primates to create organs for human (...) use. (shrink)

DEFORGE R and SHAW J. Nursing Inquiry 2012; 19: 83–95 Back‐ and fore‐grounding ontology: exploring the linkages between critical realism, pragmatism, and methodologies in health & rehabilitation sciencesAs two doctoral candidates in a health and rehabilitation sciences program, we describe in this paper our respective paradigmatic locations along a quite nonlinear ontological‐epistemological‐axiological‐methodological chain. In a turn‐taking fashion, we unpack the tenets of critical realism and pragmatism, and then trace the linkages from these paradigmatic locations through to the methodological choices (...) that address a community‐based research problem. Beyond serving as an answer to calls for academics in training to demonstrate philosophical‐theoretical‐methodological integrity and coherence in their scholarship, this paper represents critical realism and its fore‐grounding of a deeply stratified ontology in reflexive relation to pragmatism and its back‐grounding of ontology. We conclude by considering the merits and challenges of conducting research from within singular versus proliferate paradigmatic perspectives. (shrink)

Offering an original contribution to the field of luxury and fashion studies, this edited collection takes a philosophical perspective, addressing the idea that humans need luxury. From this framework it delves deep into two particular dimensions of luxury, emotions and society, and concludes with cases of brand building in order to illustrate the two dimensions at work. Comparative analysis between countries is brought together with an emphasis on China. Chapters address the ongoing growth in the market, as well as the (...) significant changes in the sector brought about by fast international expansion and an increased focus on ethical supply and sustainability, making the book an insightful read for scholars of fashion business, luxury and branding. (shrink)