African researchers and their collaborators have been making significant contributions to useful research findings and discoveries in Africa. Despite evidence of scientific misconduct even in heavily regulated research environments, there is little documented information that supports prevalence of research misconduct in Africa. Available literature on research misconduct has focused on the developed world, where credible research integrity systems are already in place. Public attention to research misconduct has lately increased, calling for attention to weaknesses in current research policies and regulatory (...) frameworks. Africa needs policies, structural and governance systems that promote responsible conduct of research. To begin to offset this relative lack of documented evidence of research misconduct, contributors working in various research institutions from nine African countries agreed to share their experiences to highlight problems and explore the need to identify strategies to promote research integrity in the African continent. The experiences shared include anecdotal but reliable accounts of previously undocumented research misconduct, including some ‘normal misbehavior’ of frontline staff in those countries. Two broad approaches to foster greater research integrity are proposed including promotion of institutional and individual capacity building to instil a culture of responsible research conduct in existing and upcoming research scientist and developing deterrent and corrective policies to minimize research misconduct and other questionable research practices. By sharing these experiences and through the strategies proposed, the authors hope to limit the level of research misconduct and promote research integrity in Africa. (shrink)

While aging research and policy aim to promote ‘health’ at all ages, there remains no convincing explanation of what this ‘health’ is. In this paper, I investigate whether we can find, implicit within the sciences of aging, a way to know what health is and how to measure it, i.e. a theory of health. To answer this, I start from scientific descriptions of aging and its modulators and then try to develop some generalizations about ‘health’ implicit within this research. After (...) discussing some of the core aspects of aging and the ways in which certain models describe spatial and temporal features specific to both aging and healthy phenotypes, I then extract, explicate, and evaluate one potential construct of health in these models. This suggests a theory of health based on the landscape of optimized phenotypic trajectories. I conclude by considering why it matters for more candidate theories to be proposed and evaluated by philosophers and scientists alike. (shrink)

Philosophers have recently argued that traditional discussions of virtue and character presuppose an account of behaviour that experimental psychology has shown to be false. Behaviour does not issue from global traits such as prudence, temperance, courage or fairness, they claim, but from local traits such as sailing-in-rough-weather-with-friends-courage and office-party-temperance. The data employed provides evidence for this view only if we understand it in the light of a behaviourist construal of traits in terms of stimulus and response, rather than in the (...) light of the more traditional construal in terms of inner events such as inclinations. More recent experiments have shown this traditional conception to have greater explanatory and predictive power than its behaviourist rival. So we should retain the traditional conception, and hence reject the proposed alteration to our understanding of behaviour. This discussion has further implications for future philosophical investigations of character and virtue. Key Words: character traits • situationism • social psychology • virtue ethics. (shrink)

Various influential ethical theories propose that we should strive to develop morally sound character traits, either because good actions are those that issue from good character traits, or because good traits are those that generally incline us toward actions that are good for some independent reason such as the intentions with which they are performed or the consequences of performing them. This proposal obviously raises questions about the nature and origins of character traits, and our degree of control over them. (...) For if we cannot develop our traits then this proposal should be abandoned, and if we can then we need to know how this is best achieved. (shrink)

ArgumentThe tension between theoretical and practical knowledge was particularly problematic for trainee physicians. Unlike civic apprenticeships in surgery and pharmacy, in early modern England there was no standard procedure for obtaining education in the practical aspects of the physician’s role, a very uncertain process of certification, and little regulation to ensure a suitable reward for their educational investment. For all the emphasis on academic learning and international travel, the majority of provincial physicians returned to practice in their home area, because (...) establishing a practice owed more to networks of kinship, patronage and credit than to formal qualifications. Only when practitioners had to rely solely on their professional qualification to establish their status as young practitioners that the community could trust would proposals to reform medical education, such as those put forward to address a crisis of medicine in Restoration London, which are examined here, be converted into national regulation of medical education in the early nineteenth century, although these proposals prefigured many informal developments in medical training in the eighteenth century. (shrink)

O artigo tem por objeto o estudo dos limites do sigilo bancário e empresarial na concessão de empréstimos pelo Banco Nacional de Desenvolvimento Econômico e Social (BNDES), a partir da contraposição entre o dever de transparência da Administração Pública e os direitos fundamentais à intimidade e livre iniciativa. Através do método dedutivo e revisão bibliográfica, analisou-se as normas constitucionais envolvidas, a evolução da transparência nas operações de empréstimos do referido banco público, além de importante julgado do Supremo Tribunal Federal (STF) (...) sobre o tema, traçando-se ao fim, alguns limites aos direitos fundamentais em confronto. (shrink)

This paper explores the practice of rewilding and its implications for environmental aesthetic values, qualities and experiences. First, we consider the temporal dimensions of rewilding in regard to the emergence of particular aesthetic qualities over time, and our aesthetic appreciation of these. Second, we discuss how rewilding potentially brings about difficult aesthetic experiences, such as the unscenic and the ugly. Finally, we make progress in critically understanding how rewilding may be understood as a distinctive form of ecological restoration, while resisting (...) the assimilation of rewilding into wilderness discourses. (shrink)

The goal of this project is to argue for ethics as a necessary component of the institutional health. The authors offer an epidemiology of ethics for a large, metropolitan, very-high-research-activity university in the U.S. Where epidemiology of a pandemic looks at quantifiable data on infection and exposure rates, control, and broad implications for public health, an epidemiology of ethics looks to parallel data on those same themes. Their hypothesis is that knowing more about how undergraduates are exposed to ethics will (...) help us understand to what extent they are infected with interest in ethics literacy, and potentially what immunity they develop against unethical and unprofessional conduct. These data also tell a story about the ethical health of institutions: to what extent its members are empowered to cultivate a culture of ethics and inoculated against ethical missteps. The authors argue that pro-ethics inoculation at research institutions is shaped by issues of complexity, connotation, and collaboration. These issues make assessment of where ethics is taught all the more difficult. The methodology used in this project can readily be taken up by other institutions, with much to be learned from inter-institutional comparisons about the distribution of ethics across the curriculum and within the disciplines. (shrink)

The discovery of the engram, the physical substrate of memory, is a central challenge for the sciences of memory. Following the application of optogenetics to the neurobiological study of memory, scientists and philosophers claim that the engram has been found. In this paper, I evaluate the implications of applying optogenetic tools to the localization of the engram. I argue that conceptions of engram localization need to be revised to be made consistent with optogenetic studies of the engram. I distinguish between (...) challenges to vehicle and content localization. First, I consider the silent engram hypothesis. According to this hypothesis, optogenetic studies indicate that synaptic efficacy, the traditional engram-bearing vehicle, is important merely for retrieval. I argue that this interpretation rests upon a misunderstanding of accessibility. Second, I argue that optogenetic-based strategies and findings conflict with preservationist and constructivist views on memory storage. There is an enduring trace, but stored content may change over time and experience, resulting in doubt about what constitutes a single engram. (shrink)

In this paper, I will connect some of the philosophical research on non-doxastic accounts of faith to some psychological research on grit. In doing so I hope to advance the debate on both the nature and value of faith by connecting some philosophical insights with some empirical grounding. In particular, I will use Duckworth’s research to show that seeing faith as grit both captures the philosophical motivations for non-doxastic accounts of faith and comes with empirical backing that such faith is (...) voluntary and can be both valuable and rational. (shrink)

Third-party punishment (TPP) occurs when the perpetrator of a transgression is punished by an individual who is not the victim of the transgression and, therefore, not directly affected by it. As F...

The practice of appealing to esoteric intuitions, long standard in analytic philosophy, has recently fallen on hard times. Various recent empirical results have suggested that philosophers are not currently able to distinguish good intuitions from bad. This paper evaluates one possible type of approach to this problematic methodological situation: calibration. Both critiquing and building on an argument from Robert Cummins, the paper explores what possible avenues may exist for the calibration of philosophical intuitions. It is argued that no good options (...) are currently available, but leaves open the real possibility of such a calibration in the future. (shrink)

It’s generally assumed that, if an agent x acts by ϕ-ing, then there occurs an event which is x’s ϕ-ing. But what about when an agent tries to do something? Are there such things as attempts? The standard answer is ‘Yes’. But in a series of articles, and now a book, David-Hillel Ruben has argued that the answer is ‘No’: what happens when x tries to ϕ isn’t that an attempt occurs; rather, what happens is simply that a certain subjunctive (...) conditional fact obtains; x tries to ϕ just in case, had all the necessary conditions for success obtained, x would have intentionally ϕ-ed. I defend the existence of attempts. Following Ruben, I frame the issue in terms of the logical form of trying sentences. Against Ruben’s view that such sentences express subjunctive conditionals, I argue that they express existential quantifications over attempts qua events. Thus, trying sentences are true only if attempts qua events exist. (shrink)

Much of the critical praise for the film concerns the first of these aims. Bigelow’s use of at least four film crews for every scene affords the sense of being present in the situation, continuously shifting perspective, alert to possible danger. The relative anonymity of the scenery, clearly somewhere in the Middle East but not clearly anywhere in particular, fosters this uneasy sense of immersion in an unfamiliar scenario where the sources of danger are unpredictable. Protracted periods of silence, punctuated (...) by incidental sounds that often turn out to be irrelevant, increase this tension. The occasional quiet ring of tinnitus imparts a sense of the incessant nature of the soldiers’ anxiety. Much of the negative criticism of the film, on the other hand, concerns the psychology of its central characters. Some veterans of the war in Iraq have claimed that it is a wildly inaccurate portrayal of the attitudes and behaviour of professional soldiers. (shrink)

According to ‘composition as identity’, a composite object is identical to all its parts taken together. Thus, a plurality of composite objects is identical to the plurality of those objects’ parts. This has the consequence that, e.g., the bricks which compose a brick wall are identical to the atoms which compose those bricks, and hence that the plurality of bricks must include each of those atoms. This consequence of CAI is in direct conflict with the standard analysis of plural definite (...) descriptions. According to that analysis, the denotation of ‘the bricks’ can include only bricks. It seems, then, that if CAI is true, ‘the bricks’ doesn’t denote anything; more generally, if CAI is true, there are fewer pluralities than we ordinarily think. I respond to this argument by developing an alternative analysis of plural descriptions which allows the denotation of ‘the bricks’ to include non-bricks. Thus, we can accept CAI, while still believing in all the pluralities we could want. As a bonus, my approach to plural descriptions and plural comprehension blocks recent arguments to the effect that CAI entails compositional nihilism. (shrink)

Johnson-Laird and Byrne present a theory of conditional inference based upon the manipulation of mental models. In the present paper, the theory is critically examined with regard to its ability to account for psychological data, principally with respect to the rate at which people draw the four basic inferences of modus ponens, denial of the antecedent, affirmation of the consequent and modus tollens. It is argued first that the theory is unclear in its definition and in particular with regard to (...) predictions of problem difficulty. Clarification and specification of principles are consequently provided here. Next, it is argued that there are a number of phenomena in the conditional reasoning literature for which the theory cannot account in its present form. Specifically, the relatively frequency of DA and AC inferences on affirmative conditionals is not as predicted by the theory, differences occur between inferences on if then and only if rules beyond the capacity of the theory to explain and there is no account of the “negative conclusion bias” observed when negated components are introduced into the rules. A number of revisions to the mental model theory of conditional reasoning are proposed in order to account for these findings. (shrink)

This article examines the philosophical methodology of intuitions beginning with an argument developed by Max Deutsch and Herman Cappelen over the descriptive adequacy of what Cappelen calls “methodological rationalism”, and their own preferred view, “intuition nihilism”. Based on inadequacies in both accounts, it offers a descriptive take on intuition-deploying philosophical practice today via what it calls “Protean Crypto-Rationalism”. It then describes the epistemic profile of the appeal to intuition, listing four key aspects of the basic shape of intuition-deploying philosophical practice: (...) primacy of cases, flexibility of report format, freedom of stipulation, and interpretation-hungry. It also considers several sources of error for intuitions featured in at least the informal methodological lore of philosophy, namely: misconstruals, modal confusions, pragmatics/semantics confusion, and “tin ear”. Finally, it explores the problem of methodological ignorance and inferential demand, particularly the typical practices of philosophical inference that operate on the premises delivered by appeal to intuitions. (shrink)

In this paper I consider what might be my best response to various difficulties and challenges that emerged at a conference held at the University of Kent in December 2004, the contributions to which are given in the same volume. I comment on Crisp's distinction between ultimate and non-ultimate reasons, and reply to McKeever and Ridge on default reasons, and to Norman on the idea of a reason for action. I don't here consider what other particularists might want to say; (...) I certainly don't think that my way of doing these things is the only possible one, but not surprisingly I am interested in seeing what resources it might have to defend itself. (shrink)

The last two decades have witnessed a crescendo of allegations that clinical translation is rife with waste and inefficiency. Patient advocates argue that excessively demanding regulations delay access to life‐saving drugs, research funders claim that too much basic science languishes in academic laboratories, journal editors allege that biased reporting squanders public investment in biomedical research, and drug companies (and their critics) argue that far too much is expended in pharmaceutical development.But how should stakeholders evaluate the efficiency of translation and proposed (...) reforms to drug development? Effective reforms require an accurate model of the systems they aspire to improve—their components, their proper functions, and their pathologies. However, there is currently no explicit and well‐developed model of translation for evaluating such criticisms.In what follows, we offer an explicit model of clinical translation. Many discussions of clinical translation and its pathologies presume that its main output is tangible: new drugs, vaccines, devices, and diagnostics. We disagree. We argue that the principal output of clinical translation is information—in particular, information about the coordinated set of materials, practices, and constraints needed to safely unlock the therapeutic or preventive activities of drugs, biologics, and diagnostics. To develop this information calls for a process far different from a simple linear progression of clinical trials; it requires exploratory sampling of many different elements in this set. Our model points to some limitations and liabilities of influential proposals for reforming research. It also reveals some underrecognized opportunities for improving the efficiency of clinical translation. (shrink)

Because emotion regulation processes operate over time, they potentially change the context in which subsequent ER processes occur. To test this proposal, fifty-two healthy participants completed the ER choice task. Thirty standardized low- and high-intensity negative images were used to generate different emotional contexts in which participants selected between distraction or reappraisal strategies to decrease the intensity of their negative emotion. Participants then implemented their selected strategy and rated their negative emotion. Using a dynamic perspective, we examined as predictors of (...) ER strategy choice, in addition to current stimulus intensity, several contextual factors from the immediately preceding trial: preceding stimulus intensity and strategy choice, and the intensity of negative affect following the previous strategy implementation and thus preceding the current trial. Results replicated earlier findings that participants are more likely to choose distraction for high-intensity images. Extending earlier findings, selecting reappraisal in the preceding trial and greater negative affect preceding the current trial were associated with lower odds of choosing distraction. The lack of significant interactions among the current and preceding trial factors suggests that these effects on ER choice were direct and not through moderating the effect of current stimulus intensity. These findings support dynamic theories of ER. (shrink)

Matching bias in conditional reasoning consists of a tendency to select as relevant cases whose lexical content matches that referred to in the conditional statement, regardless of the presence of negatives. Evans demonstrated that use of explicit rather than implicit negative cases markedly reduced the matching bias effect on the conditional truth table task. In apparent contrast, recent studies of explicit negation on the Wason selection task have failed to find evidence of logical facilitation. Experiment 1 of the present study (...) strongly replicated the Evans findings and extended them to three forms of conditional statement. Experiments 2 and 3 showed further that the use of explicit negatives removed completely the matching bias effect on the Wason selection task. However, consistent with other recent studies, this elimination of bias didnotlead to facilitation of correct responding. The findings are interpreted as providing evidence that matching bias reflects a linguistically cued relevance effect. (shrink)

Presenting a new political and historical theory of the mixed economy, this book is a convincing argument for a challenging social ideal - democratic communitarianism. Individualistic notions of liberty, equality and prosperity are too central to modern life and they need to be balanced by values of `community' and co-operation. Arguing that such a transformation is possible and practical, the author argues that long-term changes must be achieved before economic success can take place in a more fraternal, participative, and democratic (...) society. (shrink)

Virtue in an Age of Identity Politics examines current social justice activism through the lens of Stoic philosophy. While developing a critique of Critical Social Justice, it also explains how Stoicism overlaps with Critical Social Justice in the interest of healing social divisions and promoting honest and nuanced conversations about justice.

How can one Jewish thinker's natural law theory explain morality, divine commandments, and human ordinances; and how do we assess the consistency of that theory when it is mentioned in connection with such diverse areas? The answer lies in the changing meaning of reason in Novak's writings.

What contribution can political philosophers make to policy questions, such as the best configuration of the welfare state? On one view, political philosophers set out abstract theories of justice that can guide policy makers in their attempt to transform existing institutions. Yet it rarely seems the case that such a model is used in practice, and it therefore becomes unclear how political philosophy can contribute to policy debates. Following a suggestion from Margaret MacDonald, I consider the view that political philosophers (...) can contribute by drawing attention to relatively neglected values. I develop this view to add the possibility that political philosophers can try to correct a situation in which a particular value, though important, can come to be too highly emphasised. I illustrate the account by considering the rise of the value of ‘responsibility’ in the welfare state, and ultimately the damage that has been done to society to disadvantaged groups by the over-insistence on the importance of responsibility. (shrink)