Recently, an article by Toshiko Tanaka, Takao Yamamoto, and Masahiko Haruno garnered a fair bit of media attention; in “Brain response patterns to economic inequity predict present and future depression indices”, they reported research that purported to show that “pro-social” individuals were more upset by unequal outcomes that didn’t directly disadvantage them than were “individualists.” Further, being pro-social was associated with a higher chance of developing depression. They linked this research with research showing that economic inequality is associated with poor (...) health outcomes, including higher rates of depression. (They cite the epidemiologists Richard Wilkinson and Kate Pickett’s 2006 work... (shrink)

A vital and timely reminder that modern life owes as much to outlandish thinking as to dominant ideologies What do the Nag Hammadi library, Dan Brown's The Da Vinci Code, speculative feminist historiography, Marcus Garvey's finances, and maps drawn by asylum patients have in common? Jonathan P. Eburne explores this question as never before in Outsider Theory, a timely book about outlandish ideas. Eburne brings readers on an adventure in intellectual history that stresses the urgency of taking seriously--especially in (...) an era of fake news--ideas that might otherwise be discarded or regarded as errant, unfashionable, or even unreasonable. Examining the role of such thinking in contemporary intellectual history, Eburne challenges the categorical demarcation of good ideas from flawed, wild, or bad ones, addressing the surprising extent to which speculative inquiry extends beyond the work of professional intellectuals to include that of nonprofessionals as well, whether amateurs, unfashionable observers, or the clinically insane. Considering the work of a variety of such figures--from popular occult writers and gnostics to so-called outsider artists and pseudoscientists--Eburne argues that an understanding of its circulation and recirculation is indispensable to the history of ideas. He devotes close attention to ideas and texts usually omitted from or marginalized within orthodox histories of literary modernism, critical theory, and continental philosophy, yet which have long garnered the critical attention of specialists in religion, science studies, critical race theory, and the history of the occult. In doing so he not only sheds new light on a fascinating body of creative thought but also proposes new approaches for situating contemporary humanities scholarship within the history of ideas. However important it might be to protect ourselves from "bad" ideas, Outsider Theory shows how crucial it is for us to know how and why such ideas have left their impression on modern-day thinking and continue to shape its evolution. (shrink)

As evidenced in recent literature in moral philosophy, commending actions on their propensity to develop enduring moral traits is not the province of the virtue theorist alone. For however we understand the moral goals of human beings and the nature of right action we recognize that a temperate, just or beneficent person is more likely to conform to the demands of morality than one lacking in these virtues. If this idea is used as a standard for assessing the worth of (...) activities generally and engaging in sporting activity particularly it becomes clear that the highest level of athletic engagement, that is, professional sports, is often morally problematic. The not uncommon phenomenon of athletic underperformance once a sizable, secure contract has been achieved, the expanding quantity and severity of verbal abuse directed at officials and other athletes, as well as the increasing incidence of on-field violence, raise concern that developing moral virtues is no longer a goal of professional sporting activities. This conclusion, however, is not a result of the concept of sport itself or even the idea of professional sport. Both amateur and professional sport are capable of promoting moral development in their participants by making possession of certain virtues a condition for success in that activity. So the problem lies not in the conceptual details of sporting activity but rather in the formulation or prosecution of the rules and expectations governing the sport in question. The essay argues that not only is sport capable of being a worthwhile activity but that there is a sport that in fact generally meets the conditions for being a worthwhile activity, namely professional cricket. In defending this claim it is shown that it is not an essential feature of professional cricket that garners our moral commendation but rather a complex set of contingent features: the Laws of Cricket, the enforcement of those laws and the historico-social context in which the game is set. (shrink)

Amidst the politically-charged climate of seventeenth-century England, a small, but influential makeshift group of Baptist divines developed an eschatological system that both encouraged their congregations to greater holiness and threatened the very existence of the proto-denomination. Even as most of the nascent group of dissenting congregations known as Baptists sought acceptance by the more mainstream dissent, those divines who accepted this particular form of millenarianism garnered unwanted attention from the authorities as they pressed remarkably close to the line of radical (...) dissidence. Three of those Baptist divines—Vavasor Powell, Hanserd Knollys, and Benjamin Keach—provide helpful insights both into the range of millenarianism adopted by this group of Baptists and into the legitimacy of the charges of radicalism. This article examines the published works of these three ministers, comparing their visions for the eschatological future and analyzing the charges of radicalism placed against them by their contemporaries. (shrink)

Jonathan Walkan challenges cognitive science's dominant model of mental representation and proposes a novel, well-devised alternative. The traditional view in the cognitive sciences uses a linguistic model of mental representation. That logic-based model of cognition informs and constrains both the classical tradition of artificial intelligence and modeling in the connectionist tradition. It falls short, however, when confronted by the frame problem---the lack of a principled way to determine which features of a representation must be updated when new information becomes (...) available. So far, proposed alternatives, including the imagistic model, have not resolved the problem. Waskan proposes the Intrinsic Cognitive Models hypothesis, according to which representational states can be concpetualized as the cognitive equivalent of scale models.Waskan argues further that the proposal that humans harbor and manipulate cognitive counterparts to scale models offers the only viable explanation for what most clearly differentiates humans from other creatures: the capacity to engage in truth-preserving manipulation of representations. The ICM hypothesis, he claims, can be distinguished from sentence-based accounts of truth preservation in a way that is fully compatible with what is known about the brain. (shrink)

While aging research and policy aim to promote ‘health’ at all ages, there remains no convincing explanation of what this ‘health’ is. In this paper, I investigate whether we can find, implicit within the sciences of aging, a way to know what health is and how to measure it, i.e. a theory of health. To answer this, I start from scientific descriptions of aging and its modulators and then try to develop some generalizations about ‘health’ implicit within this research. After (...) discussing some of the core aspects of aging and the ways in which certain models describe spatial and temporal features specific to both aging and healthy phenotypes, I then extract, explicate, and evaluate one potential construct of health in these models. This suggests a theory of health based on the landscape of optimized phenotypic trajectories. I conclude by considering why it matters for more candidate theories to be proposed and evaluated by philosophers and scientists alike. (shrink)

Philosophers have recently argued that traditional discussions of virtue and character presuppose an account of behaviour that experimental psychology has shown to be false. Behaviour does not issue from global traits such as prudence, temperance, courage or fairness, they claim, but from local traits such as sailing-in-rough-weather-with-friends-courage and office-party-temperance. The data employed provides evidence for this view only if we understand it in the light of a behaviourist construal of traits in terms of stimulus and response, rather than in the (...) light of the more traditional construal in terms of inner events such as inclinations. More recent experiments have shown this traditional conception to have greater explanatory and predictive power than its behaviourist rival. So we should retain the traditional conception, and hence reject the proposed alteration to our understanding of behaviour. This discussion has further implications for future philosophical investigations of character and virtue. Key Words: character traits • situationism • social psychology • virtue ethics. (shrink)

Various influential ethical theories propose that we should strive to develop morally sound character traits, either because good actions are those that issue from good character traits, or because good traits are those that generally incline us toward actions that are good for some independent reason such as the intentions with which they are performed or the consequences of performing them. This proposal obviously raises questions about the nature and origins of character traits, and our degree of control over them. (...) For if we cannot develop our traits then this proposal should be abandoned, and if we can then we need to know how this is best achieved. (shrink)

This paper is an attempt to answer the question, ‘could there be causation in a timeless world?’ My conclusion: tentatively, yes. The paper and argument have three parts. Part one introduces salient issues and spells out the importance of this line of investigation. Section two of the paper reviews recent arguments due to Baron and Miller, who argue in favour of the possibility of causation in a timeless world, and looks to reject their arguments developed there. Section three is a (...) response to a response. In their, Baron and Miller also argue that an argument in favour of the possibility of causation at timeless worlds, that I put forward, is an argument that fails. In section three, my response to Baron and Miller is that their argument against me succeeds, but that there is a nearby argument that we can appeal to in order to demonstrate the possibility of causation at timeless worlds. (shrink)

ArgumentThe tension between theoretical and practical knowledge was particularly problematic for trainee physicians. Unlike civic apprenticeships in surgery and pharmacy, in early modern England there was no standard procedure for obtaining education in the practical aspects of the physician’s role, a very uncertain process of certification, and little regulation to ensure a suitable reward for their educational investment. For all the emphasis on academic learning and international travel, the majority of provincial physicians returned to practice in their home area, because (...) establishing a practice owed more to networks of kinship, patronage and credit than to formal qualifications. Only when practitioners had to rely solely on their professional qualification to establish their status as young practitioners that the community could trust would proposals to reform medical education, such as those put forward to address a crisis of medicine in Restoration London, which are examined here, be converted into national regulation of medical education in the early nineteenth century, although these proposals prefigured many informal developments in medical training in the eighteenth century. (shrink)

O artigo tem por objeto o estudo dos limites do sigilo bancário e empresarial na concessão de empréstimos pelo Banco Nacional de Desenvolvimento Econômico e Social (BNDES), a partir da contraposição entre o dever de transparência da Administração Pública e os direitos fundamentais à intimidade e livre iniciativa. Através do método dedutivo e revisão bibliográfica, analisou-se as normas constitucionais envolvidas, a evolução da transparência nas operações de empréstimos do referido banco público, além de importante julgado do Supremo Tribunal Federal (STF) (...) sobre o tema, traçando-se ao fim, alguns limites aos direitos fundamentais em confronto. (shrink)

The hemidesmosome is a complex junction containing many proteins. The keratin cytoskeleton attaches to its cytoplasmic plaque, while its transmembrane elements interact with components of the extracellular matrix. Hemidesmosome assembly involves recruitment of α6β4 integrin heterodimers, as well as cytoskeletal elements and cytoskeleton-associated proteins to the cell surface. In our cell culture models, these phenomena appear to be triggered by laminin-5 in the extracellular matrix. Cell interaction with laminin-5 apparently induces both phosphorylation and dephosphorylation of subunits of α6β4 integrin. There (...) is emerging evidence that such events are necessary for subsequent cytoskeleton anchorage to the hemidesmosome cytoplasmic plaque. Once assembled, the hemidesmosome plays an essential role in maintaining firm epithelial adhesion to the basement membrane, with hemidesmosome disruption being a hallmark of certain devastating blistering diseases. However, the hemidesmosome is more than just a stable anchor, as it may also be the site of signal transduction, mediated by its α6β4 integrin component. This review discusses our current knowledge of the structure and assembly of the hemidesmosome. BioEssays 20:488–494, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

In 2018-2019, at the Keck School of Medicine of the University of Southern California, we developed and piloted a narrative-based health systems science intervention for patients living with HIV and medical students in which medical students co-wrote patients’ life narratives for inclusion in the electronic health record. The pilot study aimed to assess the acceptability of the “life narrative protocol” from multiple stakeholder positions and characterize participants’ experiences of the clinical and pedagogical implications of the LNP. Students were recruited from (...) KSOM. Patients and staff were recruited from the Maternal, Child, and Adolescent/Adult Center for Infectious Disease and Virology at Los Angeles County+USC Medical Center. Ten patients, seventeen students, and ten MCA staff participated in the pilot study. Qualitative methods were used to gather data from students’, patients’, and staff’s perspectives. Three themes emerged from the thematic analysis: patients’ life narratives conveyed their unique life experiences and voices; the protocol could result in wide-ranging effects on HIV care; the LNP enabled students to contribute value to patients’ healthcare. Across groups, participants considered the LNP an acceptable intervention. The LNP, its limitations, and implications for HIV care, narrative medicine, and health information technology are presented. (shrink)

The goal of this project is to argue for ethics as a necessary component of the institutional health. The authors offer an epidemiology of ethics for a large, metropolitan, very-high-research-activity university in the U.S. Where epidemiology of a pandemic looks at quantifiable data on infection and exposure rates, control, and broad implications for public health, an epidemiology of ethics looks to parallel data on those same themes. Their hypothesis is that knowing more about how undergraduates are exposed to ethics will (...) help us understand to what extent they are infected with interest in ethics literacy, and potentially what immunity they develop against unethical and unprofessional conduct. These data also tell a story about the ethical health of institutions: to what extent its members are empowered to cultivate a culture of ethics and inoculated against ethical missteps. The authors argue that pro-ethics inoculation at research institutions is shaped by issues of complexity, connotation, and collaboration. These issues make assessment of where ethics is taught all the more difficult. The methodology used in this project can readily be taken up by other institutions, with much to be learned from inter-institutional comparisons about the distribution of ethics across the curriculum and within the disciplines. (shrink)

The discovery of the engram, the physical substrate of memory, is a central challenge for the sciences of memory. Following the application of optogenetics to the neurobiological study of memory, scientists and philosophers claim that the engram has been found. In this paper, I evaluate the implications of applying optogenetic tools to the localization of the engram. I argue that conceptions of engram localization need to be revised to be made consistent with optogenetic studies of the engram. I distinguish between (...) challenges to vehicle and content localization. First, I consider the silent engram hypothesis. According to this hypothesis, optogenetic studies indicate that synaptic efficacy, the traditional engram-bearing vehicle, is important merely for retrieval. I argue that this interpretation rests upon a misunderstanding of accessibility. Second, I argue that optogenetic-based strategies and findings conflict with preservationist and constructivist views on memory storage. There is an enduring trace, but stored content may change over time and experience, resulting in doubt about what constitutes a single engram. (shrink)

Third-party punishment (TPP) occurs when the perpetrator of a transgression is punished by an individual who is not the victim of the transgression and, therefore, not directly affected by it. As F...

‘Public justice’ is one of the most widely-invoked of the many distinctive terms coined by Herman Dooyeweerd but, strangely, one of the least well analysed. Dooyeewerd holds that that the identity of the state is defined by a single, integrating and directing norm, the establishment of ‘public justice’. Elaborating the implications of this claim has occupied much neo-Calvinist political reflection and guided much political action inspired by that movement. Yet surprisingly little sustained theoretical reflection has been devoted in recent times (...) to examining its inner meaning and coherence. This article offers some preliminary groundwork necessary to that theoretical project. The first part presents a close reading of Dooyeweerd’s account of public justice, identifies ambiguities and inconsistencies in that account, and suggests a reconstruction displaying its wide-ranging dynamic thrust more prominently. The second part identifies two substantial challenges confronting this account: its relative neglect of processes of democratic deliberation and advocacy, and its underdeveloped critical potentials. (shrink)

There is a well-developed literature on trust. Distrust, on the other hand, has gathered far less attention in the philosophical literature. A recent exception to that trend in the philosophical literature is Hawley who develops a unified account of both trust and distrust. My aim in this paper is to present arguments against her account of trust and distrust, though then to also suggest a patch.

In this paper we focus on conversational thinking to demonstrate the value of public reasoning in building a decent world and true democracies. We shall take into account the views of selected scholars, especially John Rawls and Jürgen Habermas, on law and democratic practice, to explain why post-colonial Africa is weighed down by sociopolitical hegemonies that have aversion to their opposition and eliminate room for strong institutions, rule of law and human rights. In light of conversational thinking, this eliminates any (...) chance for “creative struggle,” i.e. a philosophers struggle against the post-colonial imaginary/social agents to dethrone strong individuals and create strong institutions. In the absence of these indices which a conversational orientation may engender, it is difficult to transform bogus democracy into true democracy and thus to create a decent society. Post-colonial Africa mired in social regression, political crisis and economic stagnation urgently needs conversational tonics to overcome the ineffectiveness of bogus democracy. We postulate a thesis about three structural transformations forming what we call Democratic Transformational Programme. (shrink)

It’s generally assumed that, if an agent x acts by ϕ-ing, then there occurs an event which is x’s ϕ-ing. But what about when an agent tries to do something? Are there such things as attempts? The standard answer is ‘Yes’. But in a series of articles, and now a book, David-Hillel Ruben has argued that the answer is ‘No’: what happens when x tries to ϕ isn’t that an attempt occurs; rather, what happens is simply that a certain subjunctive (...) conditional fact obtains; x tries to ϕ just in case, had all the necessary conditions for success obtained, x would have intentionally ϕ-ed. I defend the existence of attempts. Following Ruben, I frame the issue in terms of the logical form of trying sentences. Against Ruben’s view that such sentences express subjunctive conditionals, I argue that they express existential quantifications over attempts qua events. Thus, trying sentences are true only if attempts qua events exist. (shrink)

Much of the critical praise for the film concerns the first of these aims. Bigelow’s use of at least four film crews for every scene affords the sense of being present in the situation, continuously shifting perspective, alert to possible danger. The relative anonymity of the scenery, clearly somewhere in the Middle East but not clearly anywhere in particular, fosters this uneasy sense of immersion in an unfamiliar scenario where the sources of danger are unpredictable. Protracted periods of silence, punctuated (...) by incidental sounds that often turn out to be irrelevant, increase this tension. The occasional quiet ring of tinnitus imparts a sense of the incessant nature of the soldiers’ anxiety. Much of the negative criticism of the film, on the other hand, concerns the psychology of its central characters. Some veterans of the war in Iraq have claimed that it is a wildly inaccurate portrayal of the attitudes and behaviour of professional soldiers. (shrink)

According to ‘composition as identity’, a composite object is identical to all its parts taken together. Thus, a plurality of composite objects is identical to the plurality of those objects’ parts. This has the consequence that, e.g., the bricks which compose a brick wall are identical to the atoms which compose those bricks, and hence that the plurality of bricks must include each of those atoms. This consequence of CAI is in direct conflict with the standard analysis of plural definite (...) descriptions. According to that analysis, the denotation of ‘the bricks’ can include only bricks. It seems, then, that if CAI is true, ‘the bricks’ doesn’t denote anything; more generally, if CAI is true, there are fewer pluralities than we ordinarily think. I respond to this argument by developing an alternative analysis of plural descriptions which allows the denotation of ‘the bricks’ to include non-bricks. Thus, we can accept CAI, while still believing in all the pluralities we could want. As a bonus, my approach to plural descriptions and plural comprehension blocks recent arguments to the effect that CAI entails compositional nihilism. (shrink)

Johnson-Laird and Byrne present a theory of conditional inference based upon the manipulation of mental models. In the present paper, the theory is critically examined with regard to its ability to account for psychological data, principally with respect to the rate at which people draw the four basic inferences of modus ponens, denial of the antecedent, affirmation of the consequent and modus tollens. It is argued first that the theory is unclear in its definition and in particular with regard to (...) predictions of problem difficulty. Clarification and specification of principles are consequently provided here. Next, it is argued that there are a number of phenomena in the conditional reasoning literature for which the theory cannot account in its present form. Specifically, the relatively frequency of DA and AC inferences on affirmative conditionals is not as predicted by the theory, differences occur between inferences on if then and only if rules beyond the capacity of the theory to explain and there is no account of the “negative conclusion bias” observed when negated components are introduced into the rules. A number of revisions to the mental model theory of conditional reasoning are proposed in order to account for these findings. (shrink)