Medical literature on the protective effects of salpingectomy against ovarian cancer has challenged Catholic health care institutions to reexamine policies that prohibit tubal sterilization at the time of cesarean section. Salpingectomy performed for a woman whose fallopian tubes are known or suspected to have a serious and present pathology—risk-reducing salpingectomy—is morally justifiable as a therapeutic intervention. However, salpingectomy performed at the time of another medically indicated procedure, such as cesarean section, on an otherwise fertile woman whose fallopian tubes are presumed (...) to be healthy—opportunistic salpingectomy—constitutes direct sterilization and fails to meet the conditions of double effect. Moreover, until magisterial guidance clarifies the right application of Catholic teaching to the specific question of opportunistic salpingectomy, Catholic health care institutions should, out of prudential judgment and to avoid scandal, avoid establishing institution policies that permit the practice. (shrink)

The leading accounts of the nature of causation divide into probability-raising and process-linkage views. On the probability-raising view, causation is rooted in the comparative probability of the effect with the cause versus without. On the process-linkage view, causation is rooted in the existence of a connecting line from cause to effect. I propose a third alternative which synthesizes these views while solving their problem cases. On this alternative, causation is rooted in the comparative probability of the connecting line to the (...) effect with the cause versus without: causes as probability raisers of processes. In the first two sections, I (briefly) outline the probability-raising and process-linkage views and identify a space of problems, and then I focus on developing the alternative probability-raisers-of-processes solution. I identify problems for this view as well, though I conclude that it is at least in important respects a step forward. (shrink)

A major work in moral philosophy by the noted Puritan divine.

The principle of exchange seems to be limited in its application, and it cannot serve as a link between utilitarianism and the idea of a market for interpersonal relations. Our preferences concern the inner states of other people as well as their overt behavior. The neglect of this aspect of our preferences is a result of the coupling of utilitarianism with behaviorism. The problem is thus behaviorism, not consequentialism. It might be argued that commensurability is wrong because it sanctions impure (...) practices - aside from any principle of exchange. In reply, it may be argued that the principle of purity is an intuitive one, which must be justified at a higher level. At the intuitive level, the purity principle competes with the view that practices are in some cases too pure already, and that blind purity cannot be maintained without educational deception. The apparent difficulty of making tradeoffs among different kinds of consequences is a problem in practice, not a problem in principle. The difficulty may indeed justify certain prescriptive rules, but a blanket prohibition against impure practices would seem to require considerable defense. (shrink)

The extreme length of chromosomal DNA requires organizing mechanisms to both promote functional genetic interactions and ensure faithful chromosome segregation when cells divide. Microscopy and genome‐wide contact frequency analyses indicate that intra‐chromosomal looping of DNA is a primary pathway of chromosomal organization during all stages of the cell cycle. DNA loop extrusion has emerged as a unifying model for how chromosome loops are formed in cis in different genomic contexts and cell cycle stages. The highly conserved family of SMC complexes (...) have been found to be required for DNA cis‐looping and have been suggested to be the enzymatic core of loop extruding machines. Here, the current body of evidence available for the in vivo and in vitro action of SMC complexes is discussed and compared to the predictions made by the loop extrusion model. How SMC complexes may differentially act on chromatin to generate DNA loops and how they could work to generate the dynamic and functionally appropriate organization of DNA in cells is explored. -/- . (shrink)

Many people have misgivings about the strategy of nuclear deterrence. Some of those misgivings centre on issues of effectiveness: safety depends entirely upon the dissuasion of an adversary. Other misgivings centre on moral concerns: the essence of deterrence is the threat, and the conditional intention, to kill millions of noncombatants. US President Reagan's Strategic Defence Initiative promised an alternative to deterrence, a strategic posture of interception of an adversary's weapons rather than preclusion of the decision to attack. It is conceived (...) as a means of ‘defending’ the United States that does not threaten anyone. In this essay I examine various SDI proposals. I argue that only one of these could justify the transition to a strategic posture of ‘defence’, and might be a genuine alternative to deterrence—the one that is least feasible technologically. Only that one could plausibly be claimed to be morally superior to deterrence—and for strategic reasons, even its claim is dubious at best. Technologically more feasible proposals are not ‘defences’, but variants of deterrence. Since that is so, the most common and dramatic claim of their moral superiority to deterrence is incoherent. (shrink)

This book defines Christian epistemological orthodoxy against such heterodox systems as Kantian phenomenology, Barthian Neoorthodoxy, Ayerian Logical Positivism, and Whiteheadian Process Thought and their respective trajectories.

Oxford Studies in Philosophy of Religion is an annual volume offering a regular snapshot of state-of-the-art work in this longstanding area of philosophy that has seen an explosive growth of interest over the past half century.

The dissertation explores the way that large-scale research projects in human genetics influence and are influenced by various social and political issues in contemporary U.S. society. In short, the dissertation argues that the same cultural assumptions which make research projects like the Human Genome Project and human behavioral genetics research seem like promising and worthwhile endeavors simultaneously lead to the results of these projects getting used to define the terms that various social issues are discussed in. In cases where the (...) issues involve conflicting agendas, those cultural assumptions that drive the research projects often point towards a specific form of resolution, a form that is often implicitly or explicitly supported by the results of the research projects themselves. ;There is, in other words, a complex relationship of mutual support between certain kinds of research projects in human genetics, the legal and social decisions made in various areas in political life, and the kinds of discourse that can exist around those same areas. This relationship is pernicious insofar as those assumptions that encourage the research and influence the way the research is used are assumptions that many people would question the wisdom of uncritically accepting. And indeed, they are assumptions that, I argue, have strong racist and sexist overtones, assumptions born out of a radically anti-egalitarian framework. Political decisions and social discourse that might otherwise seem radically racist, sexist, or classist can, once they are being made in the shadow of research undertaken under these same kinds of assumptions, be made to seem somehow natural, inevitable, or at the very least, scientifically well-motivated. (shrink)

Understanding the phenomenon of health is crucial for ageing research since there is often an implicit view on what constitutes health and how to measure it. We provide some reflections on how we might better understand and measure health, discuss the basic biological principles of survival, ageing, age-related diseases and eventual death, and end by tying these ideas together to rethink the nature of and implications for healthy ageing. We defend a more positive view on health understood in terms of (...) various phenotypic parameters, such as robustness and resilience, and show how it relates to the aim to support these parameters over time to achieve healthy ageing. Together, these ideas suggest that the most effective strategies for healthy ageing may come from the outside-in by altering those aspects of the environment that prevent robust and resilient phenotypic responses and by supporting those aspects which ensure such responses. (shrink)

This chapter provides a philosophical analysis of the different meanings of “security” and, by so doing, identifies some key features of the concept of security. I begin by establishing a number of qualities which this chapter’s conceptual analysis should ideally possess. I then make an important distinction between security as a practice and security as a state of being, and argue that more attention should be paid to the latter if our goal is to interrogate the justifiability of using security (...) practices in the context of infectious disease emergencies. The latter half of the chapter investigates three common features of contemporary accounts of security: (1) the referent object, (2) the conditions that object must satisfy to be secure, and (3) the distinction between the objective and subjective realisation of those conditions. I argue that accounts of the meaning of “security” identify a referent object and a set of conditions which must be reliable for that referent. I conclude by suggesting that a deeper engagement by moral philosophers with the concept and value of security (as a state of being) is required if we are to get very far in evaluating the justifiability of treating infectious disease emergencies as security issues. (shrink)

Charity and its fruits -- Dissertation I, Concerning the end for which God created the world -- Dissertation II, The nature of true virtue.

There are at least three core principles that define the chance role: ill the Principal Principle, l21 the Basic Chance Principle, and l31 the Humean Principle. These principles seem mutually incompatible. At least, no extant account of chance meets more than one of them. I ofier an account of chance which meets all three: L~-chance. So the good news is that L~-chance meets ill — l31. The bad news is that L~-chance turns out unlawful and unstable. But perhaps this is (...) not such bad news: L~-chance turns out to at least approximate plausible additional core principles concerning lawfulness and stability. And perhaps there is better news: one may treat 'chance' as vague, in a way that allows every core principle of chance to be met. (shrink)

The present argument assumes that teaching through modeling attempts to teach the intellectual virtues not primarily as an independent goal of education as, for example, a way to build good character, but for its value to inquiry. I argue that intellectual vices (such as being gullible, dogmatic, pigheaded, or prejudiced)—while harmful to inquiry in certain ways—are essential to its well functioning. Furthermore, to the extent that teaching models critical inquiry, there are educational lessons for which some students ought to take (...) a dogmatic or narrow minded commitment to certain hypotheses or positions; and then, insofar as this modeling works, it will promote these intellectual vices. In Part I of what follows, I develop my argument; in Part II, I respond to the objection that diversity of ideas and attitudes need not—and ought not—call upon the promotion of intellectual vices. (shrink)

Much of the critical praise for the film concerns the first of these aims. Bigelow’s use of at least four film crews for every scene affords the sense of being present in the situation, continuously shifting perspective, alert to possible danger. The relative anonymity of the scenery, clearly somewhere in the Middle East but not clearly anywhere in particular, fosters this uneasy sense of immersion in an unfamiliar scenario where the sources of danger are unpredictable. Protracted periods of silence, punctuated (...) by incidental sounds that often turn out to be irrelevant, increase this tension. The occasional quiet ring of tinnitus imparts a sense of the incessant nature of the soldiers’ anxiety. Much of the negative criticism of the film, on the other hand, concerns the psychology of its central characters. Some veterans of the war in Iraq have claimed that it is a wildly inaccurate portrayal of the attitudes and behaviour of professional soldiers. (shrink)

Narrative based real world case examples are powerful tools by which to help learners more empathetically engage the complexity of ethical conflicts and interactions, enabling clearer analysis of ecological ethical issues and overcoming apathy toward real-world responses. In this paper, I develop ecological ethical inquiry as a means by which to use narrative-based case studies to help ethicists connect to and empathize with other morally relevant individuals. I argue that ecological issues not only benefit from but also require a narrative (...) approach because of ethical and epistemic complexity. I first describe the problem of apathy toward motivation given the ethical and epistemic complexity in ecological ethics contexts; then, I offer a case study in ecological ethics that draws out this complexity; and finally, I point out several caveats concerning the conclusions I have drawn. (shrink)

This chapter contains section titled: Moral Motivation Virtue and Motivation Self‐interest and Morality What about Luck? Are Moral Considerations Overriding? Where Now? Questions for Discussion and Reflection Thinkers and Their Works, and Further Reading Notes.

This chapter contains section titled: Naturalism The Modern Debate about Naturalism Reconstructed Naturalism Non‐cognitivist Alternatives Hume and Naturalism Reconnecting Facts and Values Aristotle and Naturalism Moral Facts and Explanation What about God? Where Now? Questions for Discussion and Reflection Thinkers and Their Works, and Further Reading Notes.