In the past decade donor commitments to health have increased by 200 percent. Correspondingly, there has been a swell of new players in the global health landscape. The unprecedented, global response to a single disease, HIV/AIDS, has been responsible for a substantial portion of this boon. Numerous health success have followed this windfall of funding and attention, yet the food, fuel, and economic crises of 2008 have shown the vulnerabilities of health and development initiatives focused on short term wins and (...) reliant on a constant flow of foreign funding. For too long, the international community has responded to global health and development challenges with emergency solutions that often reflect the donor's priorities, values, and political leanings, rather than funding durable health systems that can withstand crises. Progress towards achieving the Millennium Development Goals has stalled in many countries. Disease specific initiatives have weakened health systems and limited efforts to improve maternal and child health. As we enter this era of scarce resources, there is a need to return to the foundations of the Alma Ata Declaration signed thirty years ago with the goal of providing universal access to primary healthcare. The global health community must now objectively evaluate how we can most effectively respond to the crises of 2008 and take advantage of this moment of extraordinary attention for global health and translate it into long term, sustainable health improvements for all. (shrink)

Many recent gene knockout experiments cause anatomical changes to the jaw region of mice that several investigators claim are evolutionary reversals. Here we evaluate these mutant phenotypes and the assertions of atavism. We argue that following the knockout of Hoxa-2, Dlx-2, MHox, Otx2, and RAR genes, ectopic cartilages arise as secondary consequences of disruptions in normal processes of cell specification, migration, or differentiation. These disruptions cause an excess of mesenchyme to accumulate in a region through which skeletal progenitor cells usually (...) migrate, and at a site of condensation that is normally present in mammals but that is too small to chondrify. We find little evidence that these genes, when disrupted, cause a reversion to any primitive condition and although changes in their expression may have played a role in the evolution of the mammalian jaw, their function during morphogenesis is not sufficiently understood to confirm such hypotheses. BioEssays 20:245–255, 1998.© 1998 John Wiley & Sons, Inc. (shrink)

Mit der Frage nach dem -Geist- wird ein Thema angesprochen, dem die Philosophie des deutschen Idealismus noch eine vollkommen andere Bedeutung zumessen konnte, als wir dies heute gewohnt sind. Geist in seinem Selbstsein scheint unbestimmbar geworden in einer Zeit, in der Neurobiologen funktionelle Prozesse im zentralen Nervensystem des Gehirns als korrelierende Variable zu mentalen Vorgangen beschreiben. In diesem Buch wird nach den -verstehbaren Zusammenhangen- zwischen Krankheitsvorgangen des menschlichen Seelenlebens und den Grundeigenschaften des Mentalen, insbesondere des Psychischen, gefragt.".

With reference to Mead, Peirce, speech act theory, conversation analysis, and Luhmann's phenomenological grounded version of systems theory, the paper tries to reconstruct actions as products of communication. A triadic sequence is identified as the elementary unit for the intersubjective constitution of an act. This unit combines three achievements: (a) the constitution of meaning by sequential attribution, (b) the intersubjective coordination of attributed meanings, and (c) the reproduction of rules, guiding the process of constitution and coordination of attributed meanings. Then, (...) using the tools of systems theory and applying them to empirical results of ethnomethodology and conversation analysis, it is shown how the rule scheme is integrated in a triadic sequence, functioning on three different levels of communication. Finally, a specific form of repair after next turn is discussed, relating it to the function of preserving the structure of conversational types. The analysis of such conversational types opens a possible realm of cooperation between conversation analysis and Luhmann's version of systems theory. (shrink)

In this article, we underscore the importance of stakeholder relationships for research on stakeholder engagement. We do so by integrating a practice-based understanding with the relational view. Based on a revealing case study of a civic engagement process in a large German city, we develop a conceptual framework that explains how relational practices shape stakeholder engagement. We identify three relational practices (i.e., connecting, facilitating, and containing) and their associated outcomes (i.e., implication, solidarization, and distinction), as well as effects on stakeholder (...) heterogeneity. Our findings contribute to the relational view on stakeholder engagement by providing insights into practices that shape relationships between heterogeneous stakeholders, explaining how these relational practices influence stakeholder heterogeneity, and identifying unintended impacts of stakeholder engagement. (shrink)

Inspired by theories of prosocial behavior, we tested the effect of relationship status and incentives on intended voluntary blame-taking in two experiments. Participants imagined a close family member, a close friend, or an acquaintance and read a scenario that described this person committing a minor traffic offense. The person offered either a monetary, social, or no incentive for taking the blame. Participants indicated their willingness to take the blame and reasons for and against blame-taking. Overall, a sizable proportion of participants (...) indicated to be willing to take the blame. Blame-taking rates were higher for family members than close friends or acquaintances in both experiments, as expected. Unexpectedly, there was no difference between a close friend and an acquaintance in Experiment 2. Social incentives did not have an effect on voluntary blame-taking in either experiment. Neither did we find an interaction between relationship status and incentives. The results highlight the importance of kin relationships in the context of voluntary blame-taking. (shrink)

James Fitzjames Stephen is remembered as a judge, legal historian, and the author of Liberty, Equality, Fraternity, a reply to J. S. Mill's late works. He is less well remembered for his journalism, though it earned him a reputation among his contemporaries as one of the most trenchant writers on topics ranging across the social, religious, political, moral, and philosophical questions debated in his time. It was largely in his journalistic writing that Stephen set forth his views on these questions. (...) Despite such a reputation, however, only a small proportion of this writing was collected during his lifetime, and very little has been republished since his death.Selected Writings of James Fitzjames Stephen: On Society, Religion, and Government includes thirty-five essays expressing Stephen's views on the questions of his day, which have not lost their interest in ours. He wrote at a time when much of the finest writing in English was published in periodicals, often anonymously. The essays in this volume are drawn mostly from Stephen's unsigned contributions to the Saturday Review, with additions, both signed and unsigned, from other periodicals, extending from the 1850s to the 1880s. (shrink)

Arts education in schools frequently experiences the pressure of being validated by demonstrating quantitative impact on academic outcomes. The quantitative evidence to date has been characterized by the application of largely correlational designs and frequently applies a narrow focus on instrumental outcomes such as academically relevant competencies. The present review aims to summarize quantitative evidence from quasi-experimental and experimental studies with pre-test post-test designs on the effects of school-based arts education on a broader range of competency outcomes, including intra- and (...) interindividual competencies. A systematic literature search was conducted to identify relevant evaluation studies. Twenty-four articles reporting on 26 evaluation studies were eligible for inclusion, and their results were reviewed in terms of art domains and outcome categories. Whilst there is some evidence of beneficial effects on some competencies, for example of music education on arithmetic abilities, speech segmentation and processing speed, the evidence across arts domains and for different outcomes is limited due to small sample sizes, small number of studies, and a large range of effect sizes. The review highlights that sufficiently powered experimental studies with pre-test post-test designs evaluating arts education are sparse and that the “gold standard” of experimental research comes at the expense of a number of other study characteristics such as sample size, intervention and follow-up length. By summarizing the limitations of the current experimental research, the application of experimental designs is critically assessed and a combination with qualitative methods in mixed-method designs and choice of relevant outcomes discussed. (shrink)

Intrinsic religiosity drives ethical consumer behavior; however, previous studies regarding this connection are limited solely to a Christian cultural context. This comparative study instead includes Christian Consumers from Germany and Moslem Consumers from Turkey to determine if a specific religious community moderates the connection between intrinsic religiosity and consumer ethics. The results show that Consumers in the Turkish, Moslem subsample, exhibit an even stronger connection between religiosity and ethical consumer behavior than Consumers from the German, Christian subsample.