An influential strand of neo-Aristotelianism, represented by writers such as Philippa Foot, holds that moral virtue is a form of natural goodness in human beings, analogous to deep roots in oak trees or keen vision in hawks. Critics, however, have argued that such a view cannot get off the ground, because the neo-Aristotelian account of natural normativity is untenable in light of a Darwinian account of living things. This criticism has been developed most fully by William Fitzpatrick in his book (...) Teleology and the Norms of Nature . In this paper, I defend the neo-Aristotelian account of natural normativity, focusing on Fitzpatrick's arguments. I argue that a natural goodness view is not impugned by an evolutionary account. Nor can neo-Aristotelian life form judgments be replaced by an evolutionary view of living things. (shrink)

This essay defends Aristotelian naturalism against the objection that it is naïvely optimistic, and contrary to empirical research, to suppose that virtues like justice are naturally good while vices like injustice are naturally defective. This objection depends upon the mistaken belief that our knowledge of human goodness in action and choice must come from the natural sciences. In fact, our knowledge of goodness in human action and character depends upon a practical understanding that is possessed by someone not qua scientist (...) but qua practically wise person. I spell out some key features of this knowledge of human form, including its relation to practical reasons and its similarity to the “know-how” of crafts-persons. My account of virtue as knowledge of human form sheds light on the Aristotelian thesis that humans live according to an understanding of their own form. My account also clarifies the kinship and the divergence between Aristotelian and Kantian ethics. (shrink)

Acoustic speech output results from coordinated articulation of dozens of muscles, bones and cartilages of the vocal mechanism. While we commonly take the fluency and speed of our speech productions for granted, the neural mechanisms facilitating the requisite muscular control are not completely understood. Previous neuroimaging and electrophysiology studies of speech sensorimotor control has typically concentrated on speech sounds (i.e., phonemes, syllables and words) in isolation; sentence-length investigations have largely been used to inform coincident linguistic processing. In this study, we (...) examined the neural representations of segmental features (place and manner of articulation, and voicing status) in the context of fluent, continuous speech production. We used recordings from the cortical surface (electrocorticography (ECoG)) to simultaneously evaluate the spatial topography and temporal dynamics of the neural correlates of speech articulation that may mediate the generation of hypothesized gestural or articulatory scores. We found that the representation of place of articulation involved broad networks of brain regions during all phases of speech production: preparation, execution and monitoring. In contrast, manner of articulation and voicing status were dominated by auditory cortical responses after speech had been initiated. These results provide a new insight into the articulatory and auditory processes underlying speech production in terms of their motor requirements and acoustic correlates. (shrink)

Genetic engineering techniques (e.g., CRISPR-Cas) have led to an increase in biotechnological developments, possibly leading to uncertain risks. The European Union aims to anticipate these by embedding the Precautionary Principle in its regulation for risk management. This principle revolves around taking preventive action in the face of uncertainty and provides guidelines to take precautionary measures when dealing with important values such as health or environmental safety. However, when dealing with ‘new’ technologies, it can be hard for risk managers to estimate (...) the societal or environmental consequences of a biotechnology that might arise once introduced or embedded in society due to that these sometimes do not comply with the established norms within risk assessment. When there is insufficient knowledge, stakeholders active in early developmental stages (e.g., researchers) could provide necessary knowledge by conducting research specifically devoted to what these unknown risks could entail. In theory, the Safe-by-Design (SbD) approach could enable such a controlled learning environment to gradually identify what these uncertain risks are, to which we refer as responsible learning. In this paper, we argue that three conditions need to be present to enable such an environment: (1) regulatory flexibility, (2) co-responsibility between researchers and regulators, and (3) openness towards all stakeholders. If one of these conditions would not be present, the SbD approach cannot be implemented to its fullest potential, thereby limiting an environment for responsible learning and possibly leaving current policy behind to anticipate uncertain risks. (shrink)

Several nation states have reasons to halt the import of genetically modified organisms. The current international trend towards a regime of free trade makes such bans problematic. Whether a nation state is deemed justified in banning a certain product is strongly connected to discussions about what are acceptable criteria for proof of risk. The determination of these criteria hinges upon considerations of individual and national autonomy. This paper compares two different points of view in the debate: the WTO opposed to (...) the UN. A distinction between internal and external autonomy explains the differences in approach between the UN and the WTO. The conclusion is reached that adequate respect for autonomy requires a certain amount of flexibility in the criteria for proof of risk. (shrink)

This article is concerned with the question of how to argue about morality and ethics in relation to a severe and deadly hereditary disease. It is inspired by the uneasiness I have felt on a number of occasions when “right and wrong” is being discussed by persons at risk, professionals and in particular when discussed by outsiders. This task is not an easy one and the article tries to lay out more groundwork than it arrives at conclusions. Below follows a (...) brief introduction to my framework and some of the concepts that are important for my way of outlining the arguments that follow. Then I take a closer look at genetic knowledge, responsibility and decision making, because these seem to be important issues in my field of study. I have added ignorance to the list in order to discuss a further aspect of dealing with hereditary disease. Interestingly, ignorance (understood both as being ignorant of and ignoring) seems to be commonly applicable to describing persons living at risk for Huntington’s Disease (HD). So what does everyday conduct of life look like from an “ignorance” perspective? And how can we discuss and argue about morality and ethics taking these seemingly diverse ways of living at risk into account? Posing this question, I hope to contribute to new reflections on possibilities and constraints in people’s lives with HD as well as in research and to open up new ways of discussing “right and wrong”. (shrink)

Eberhard Gieseler lehrte von 1874 bis 1914 Physik und Landmaschinenkunde an der Landwirtschaftlichen Akademie Bonn-Poppelsdorf, daneben Meteorologie und Erdbau. Als Erster in Bonn machte er Röntgenaufnahmen, die die Ärzte benutzten. Mit Geschick warb er durch populärwissenschaftliche Vorträge für die Verbreitung physikalischer Kenntnisse, dabei benutzte er wie in seinen Vorlesungen oft selbst erdachte Apparate. Er erfand eine graphische Darstellung, die die Klimaverhältnisse an einem Ort für jeden Tag über einen langen Zeitraum überschaubar macht. Vor allem setzte er sich durch Aufsätze, eigene (...) Erfindungen, wissenschaftliche Untersuchungen und technische Ausbildung der zukünftigen Landwirte für die Einführung und Verbesserung der Landmaschinen in Deutschland ein.Eberhard Gieseler taught physics and agricultural machinery, and also meterorology and earthworks, from 1874 until 1914 at the Landwirtschaftliche Akademie in Bonn-Poppelsdorf. He was the first person in Bonn who made Röntgenograms which were of use to physicians. He strove through popular scientific lectures for the spreading of physical knowledge, often using—as in his academic lectures—apparatus which he had invented himself. He devised a graphical method by means of which the climatic conditions at a location for each day over a long period could be clearly seen. Above all, in his publications, inventions, scientific research, and technical education of future farmers, he advocated the introduction and improvement of agricultural machinery in Germany. (shrink)

This paper offers a detailed reconstruction of an exhibition about the biggest protest rally of the GDR, which took place on November 4, 1989 in Berlin. Drawing from archival sources, as well as interviews, I will outline the exhibition’s design and the intentions of its creators. Subsequently, I will establish correlations with like‑minded, as well as antagonistic efforts to musealise the events later termed the “peaceful revolution”. Their comparison will allow some conclusions about the becoming of the dominant politics of (...) memory today. By pointing to their gaps and blind spots, I want to advocate a more nuanced memory of this decisive period in German history. (shrink)

Technological developments often bring about new risks. Informed consent has been proposed as a means to legitimize the imposition of technological risks. This principle was first introduced in medical practice to assure the autonomy of the patient.The introduction of IC in the field of technological practice raises questions about the comparability of the type of informed consent. To what extent are thepossibilities to include laypeople in making decisions regarding risks similar in the technological field to giving informed consent in the (...) medical field and whatdoes this imply for the design and implementation of IC in the technological field? Medical and the technological practice are clearly alike in that both fieldsare characterized by highly specialized, technical knowledge which can be quite inaccessible to the average layperson. However, a fundamental difference ariseswith regard to the aim, knowledge of risks and exclusiveness of the practices in each field. The differences in aim imply that the necessity for each practice isperceived differently by laypeople, thus leading them to assess the respective risks differently. The differences in knowledge of risks arise from the variabilityin the ways that can be used to describe a given risk. Definition of risk in medical practice is more homogenous in this respect than the risk definition intechnological fields. Futhermore, medical practice tends to be more exclusive, leading laypeople immersed in that practice to necessarily embrace most of thefundamental underlying that practice. These differences result in divergent recommendations for the implementation of informed consent in the technological field, basically: there is a need for more extensive procedure and for less decisive authority for the individual. (shrink)

ABSTRACT This module is designed to sensitise you to the special needs of participants who belong to populations that are more vulner.

The policies of the European Union concerning the development of biofuels can be termed a lock-in. Biofuels were initially hailed as a green, sustainability technology. However evidence to the contrary quickly emerged. The European Commission proposed to alter its policies to accommodate for these effects but met with fierce resistance from a considerable number of member states who have an economic interest in these first generation biofuels. In this paper I argue that such a lock-in might have been avoided if (...) an experimental approach to governance had been adopted. Existing approaches such as anticipation and niche management either do not reduce uncertainty sufficiently or fail to explicitly address conflicts between values motivating political and economic support for new technologies. In this paper, I suggest to apply an experimental framework to the development of sustainable biobased technologies. Such an approach builds on insights from adaptive management and transition management in that it has the stimulation of learning effects at its core. I argue that these learning effects should occur on the actual impacts of new technologies, on the institutionalisation of new technologies and most specifically on the norms and values that underly policies supporting new technologies. This approach can be relevant for other emerging technologies. (shrink)

The central claim of Aristotelian naturalism is that moral goodness is a kind of species-specific natural goodness. Aristotelian naturalism has recently enjoyed a resurgence in the work of philosophers such as Philippa Foot, Rosalind Hursthouse, and Michael Thompson. However, any view that takes moral goodness to be a type of natural goodness faces a challenge: Granting that moral goodness is natural goodness for human beings, why should we care about being good human beings? Given that we are rational creatures who (...) can ‘step back’ from our nature, why should we see human nature as authoritative for us? This is the authority-of-nature challenge. In this essay, I state this challenge clearly, identify its deep motivation, and distinguish it from other criticisms of Aristotelian naturalism. I also articulate what I consider the best response, which I term the practical reason response. This response, however, exposes Aristotelian naturalism to a new criticism – that it has abandoned the naturalist claim that moral goodness is species-specific natural goodness. Thus, I argue, Aristotelian naturalists appear to face a dilemma: Either they cannot answer the authority-of-nature challenge, or in meeting the challenge they must abandon naturalism. Aristotelian naturalists might overcome this dilemma, but doing so is harder than some Aristotelians have supposed. In the final sections of the paper, I examine the difficulties in overcoming the dilemma, and I suggest ways that Aristotelians might answer the authority-of-nature challenge while preserving naturalism. (shrink)

The point of departure in this article is the Danish debate about democracyin schools. This article presents a first step in a study of how the relationshipbetween democracy and education can be understood. A juxtaposition of thetwo concepts requires, first of all, an analysis of how the concept of democracyis used in the educational debate. In this article three models of democracy areapplied as an analytical framework: a liberal model (Hobbes, Locke, Kant, Rawls,Dworkin), a communitarian model (MacIntyre, Sandel, Nussbaum) and (...) a communicative/deliberativemodel (Walzer, Benhabib, Taylor, Habermas). Numerous contradictions and tensionsbetween concepts of democracy and education can be found in such a juxtaposition,depending on which conception of democracy one chooses to apply. In this articleI discuss which conception affords us the most meaningful concept of democraticteaching. As an introduction, a brief historical overview of the interplay betweendemocracy and education in Danish school is provided. (shrink)

Respect for autonomy is problematic in relation to public health programmes such as vaccination, as the success of such programmes depends on widespread compliance. European countries have different policies for dealing with objectors to vaccination programmes. In some countries compliance is compulsory, while in others objectors are exempted or allowed to enter the programme under specific conditions. In this paper I argue that the objectors should not be treated as a homogenous group as is done in the above-mentioned policies. Objectors (...) have different arguments for not participating in vaccination programmes. Considering the value of respect for autonomy, some but not all of these arguments need to be accommodated by authorities. The concept of 'narrative autonomy' provides criteria to distinguish between tenable and untenable claims to the right to refuse vaccination. Narrative autonomy understands autonomy as essentially linked to identity, as this provides the moral framework with which we assess our first-order preferences. The above-mentioned concept of autonomy is derived from the concept of narrative identity as described by Marya Schechtman. She suggests that the application of the Articulation Constraint and the Reality Constraint enables us to establish the validity of personal narratives. Additionally, form and content features of identity, as proposed by Anthony Laden, will be used as criteria to establish the compatibility of the defectors' arguments with shared scientific and political values. Such compatibility is essential to accommodate respect for autonomy in the context of public health. (shrink)

Recent EEG studies on the early postmortem interval that suggest the persistence of electrophysiological coherence and connectivity in the brain of animals and humans reinforce the need for further investigation of the relationship between the brain’s activity and the dying process. Neuroscience is now in a position to empirically evaluate the extended process of dying and, more specifically, to investigate the possibility of brain activity following the cessation of cardiac and respiratory function. Under the direction of the Center for Healthy (...) Minds at the University of Wisconsin-Madison, research was conducted in India on a postmortem meditative state cultivated by some Tibetan Buddhist practitioners in which decomposition is putatively delayed. For all healthy baseline and postmortem subjects presented here, we collected resting state electroencephalographic data, mismatch negativity, and auditory brainstem response. In this study, we present HB data to demonstrate the feasibility of a sparse electrode EEG configuration to capture well-defined ERP waveforms from living subjects under very challenging field conditions. While living subjects displayed well-defined MMN and ABR responses, no recognizable EEG waveforms were discernable in any of the tukdam cases. (shrink)

Cancer screening programmes cause harm to individuals via overdiagnosis and overtreatment, even where they confer population-level benefit. Screening thus appears to violate the principle of non-maleficence, since it entails medically unnecessary harm to individuals. Can consent to screening programmes negate the moral significance of this harm? In therapeutic medical contexts, consent is used as a means of rendering medical harm morally permissible. However, in this paper, I argue that it is unclear that the model of consent used within therapeutic medicine (...) can be applied unproblematically to preventive medicine. Invitation to screening changes the pragmatic norms and expectations of the patient–doctor encounter such that two key principles of consent may be violated. First, the pragmatics of a medical invitation are such that patients may fail to be adequately informed, since patients appear to assume medical invitations are made with their best interests in mind, even where information to the contrary is outlined. Second, screening invitations may place pressure on patients; in the context of a medical encounter, to make an invitation to screening may constitute an inducement to accept. In order to be sure that a patient’s consent to a screening invitation is valid, we must make clear to patients that their decision to accept screening may be shaped not only by how information about screening is presented, but by the pragmatic form of the invitation itself. (shrink)

ABSTRACTPrevious work has shown that a stooped posture may activate negative mood. Extending this work, the present experiments examine how stooped body posture influences recovery from pre-existing negative mood. In Experiment 1, participants were randomly assigned to receive either a negative or neutral mood induction, after which participants were instructed to take either a stooped, straight, or control posture while writing down their thoughts. Stooped posture led to less mood recovery in the negative mood condition, and more negative mood in (...) the neutral mood condition. Furthermore, stooped posture led to more negative thoughts overall compared to straight or control postures. In Experiment 2, all participants underwent a negative mood induction, after which half received cognitive reappraisal instructions and half received no instructions. Mood-congruent cognitions were assessed through autobiographical memory recall. Again, stooped position led to less mood recovery. Notably, this was independent of regulation instruction. These findings demonstrate for the first time that posture plays an important role in recovering from negative mood. (shrink)

AbstractBackgroundEthical challenges constitute an inseparable part of daily decision-making processes in all areas of healthcare. In prehospital emergency medicine, decision-making commonly takes place in everyday life, under time pressure, with limited information about a patient and with few possibilities of consultation with colleagues. This paper explores the ethical challenges experienced by prehospital emergency personnel. MethodsThe study was grounded in the tradition of action research related to interventions in health care. Ethical challenges were explored in three focus groups, each attended by (...) emergency medical technicians, paramedics, and prehospital anaesthesiologists. The participants, 15 in total, were recruited through an internal information network of the emergency services. Focus groups were audio-recorded and transcribed verbatim.ResultsThe participants described ethical challenges arising when clinical guidelines, legal requirements, and clinicians’ professional and personal value systems conflicted and complicated decision-making processes. The challenges centred around treatment at the end of life, intoxicated and non-compliant patients, children as patients—and their guardians, and the collaboration with relatives in various capacities. Other challenges concerned guarding the safety of oneself, colleagues and bystanders, prioritising scarce resources, and staying loyal to colleagues with different value systems. Finally, challenges arose when summoned to situations where other professionals had failed to make a decision or take action when attending to patients whose legitimate needs were not met by the appropriate medical or social services, and when working alongside representatives of authorities with different roles, responsibilities and tasks.ConclusionFrom the perspective of the prehospital emergency personnel, ethical challenges arise in three interrelated contexts: when caring for patients, in the prehospital emergency unit, and during external collaboration. Value conflicts may be identified within these contexts as well as across them. A proposed model of analysis integrating the above contexts can assist in shedding light on ethical challenges and value conflicts in other health care settings. The model emphasises that ethical challenges are experienced from a particular professional perspective, in the context of the task at hand, and in a particular, the organisational setting that includes work schedules, medical guidelines, legal requirements, as well as professional and personal value systems. (shrink)

The organ of the memory was of crucial importance for Robert Hooke in his aim to improve natural history and the study of nature in general. As a mechanist he was careful to avoid the confident analogizing of his contemporaries, and he described his model in hypothetical form. However, he saw it as amenable to improvement—just as mechanically as the senses were augmented by the use of instruments. The close connection he made between a better memory mechanism and the task (...) of ‘perfecting’ the study of natural philosophy can be seen in a whole range of his activities. These included his discussion of the memory as an epistemological tool, his frequent use of devices such as lists and schemata for ordering aspects of nature and his personal memoranda. His diary, by acting as a stimulant to memory, should be seen as an integral part of his attempt to become a better natural philosopher. Both the act of daily inscription and the ordering of occurrences for effective later recall would improve his memory and his performance of his life's task as a philosopher of nature. (shrink)

What is the Problem with the Rarity of the Virtues?An important strand of the situationist challenge to Aristotelian virtue ethics rests on the following claim:Rarity Thesis: On the basis of evidence from psychological research, we are justified in believing that possession of the Aristotelian virtues is very rare.The Rarity Thesis is sometimes regarded as a problem for virtue ethics, or as an embarrassing implication of claims made by virtue ethicists.See John Doris, Lack of Character (Cambridge, UK: Cambridge University Press, 2002), (...) 58–60, 110–112; John Doris and Stephen Stich, “As a Matter of Fact: Empirical Perspectives on Ethics” in The Oxford Handbook of Contemporary Philosophy (Oxford, UK: Oxford University Press, 2005), see esp. 120–123. Mark Alfano, Character as Moral Fiction (Cambridge, UK: Cambridge University Press, 2013). For the purposes of this essay, I will use “virtue ethics” to refer to broadly Aristotelian virtue ethics. However, as many people have pointed out, Ari. (shrink)

This article is a revised version of a talk given in lieu of the Ph.D. dissertation: "Huntington´s Disease in Everyday Life. Knowledge, Ignorance and Genetic Risk". The dissertation evolves around the analysis of modern living with risk for a late onset genetic disorder. Here, three aspects of everyday lives faced with Huntington´s Disease (HD) are discussed. First, HD is one aspect of everyday living along with a variety of other aspects. The importance of risk is analysed as personal and changing (...) in changing circumstances. Second, genetic knowledge and technology are not solid universals, but situated and changing, and of varying importance in lives at risk. Last, the ethical rationalities of everyday living, research and clinical practice concerned with a hereditary condition are discussed as complex and contradictory in and across structures of social practice. (shrink)

This paper is the result of three interviews held in Paris, between the months of October and November 2015. Respondants were: the philosopher Marcel Gauchet, diretor of studies at the Ecole des Hautes Etudes EHESS; political scientist and historian of secularity, Philippe Portier, diretor of studies at the École Pratique des Hautes Études EPHE Paris-Sorbonne and historian Didier Da Silva, professor of history of ideas at the Institut Catholique de Paris. The goal pursued in the context of these interviews is (...) related to the understanding of a current perspective of religion output at the thought of Gauchet, the subject of my post-doctoral research at PUC Minas, Belo Horizonte, and at the National Program for Postdoctoral PNPD, Capes. The considerations which led the analysis proposed in this paper are guided by understanding effort of some of the characteristics of the religious phenomenon in the contemporary context. What we wonder and what is defined in this effort of understanding are the reconfigurations that mark the current stage of relations between politics and religion - reconfigurations demarcating the permeabilities and the limits of the overall spectrum of those relations. In addition, more particularly, what we present here are some thoughts on the condition of secularity and religion exit in the Brazilian context. (shrink)

One of the most startlingly original and provocatively radical scholars currently engaged in the study of culture and the concept of race.

This paper’s objective is to ascertain the current situation of the so-called exit from religion within the theories of French philosopher Marcel Gauchet. Our purpose is a comprehensive approach of some concepts that permeate his thought about the religious phenomenon. The analysis here developed is divided in four distinct parts. In the first, we explore the specific bases of Gauchet’s concept of religion. It is a concept which, as we shall see, entails a notion of exit from religion in its (...) pure state, or in the state of essence. In the second part, we address the notion of exit from religion in a broader sense of our author’s vocabulary, focusing on some of this exit’s historical process, its beginnings and major outcomes. In the third part, we aim our reflective efforts at the current situation of this exit from religion and at the novel configurations which are manifested as spiritualities outside from religion. In the fourth and last part, we seek to make a reflection on Brazil’s contemporary religiosity via the theoretical perspective established by the French philosopher. A glimpse is then made available by the analysis proposed herein, of the dynamics of the exit from religion – removing it from the stricter sphere of politics – such exit does not exclude the participation of religions in the field of the public spheres and of the civil society. (shrink)

Elf essays over de eigen geschiedenis en hoe mensen zich beter tot elkaar kunnen verhouden."--Publisher information.

Alasdair MacIntyre's account of tradition-based rationality has been the subject of much discussion, as well as the object of some recent charges of inconsistency. The author considers arguments by Jennifer Herdt, Peter Mehl, and John Haldane which attempt to show that MacIntyre's account of rationality is, in some way, inconsistent. It is argued that the various charges of inconsistency brought against MacIntyre by these critics can be understood as variations on two general types of criticism: (1) that MacIntyre's account of (...) tradition-based rationality presents a picture of rationality with inconsistent internal elements, and (2) that MacIntyre, in the act of presenting his picture of rationality, makes the sort of claims to which his own account of rationality denies legitimacy, and thus MacIntyre's account is self-referentially incoherent. In response to criticisms of the first sort, it is argued that MacIntyre can further clarify or develop his position to take the current criticisms into account without altering the fundamental aspects of his picture of rationality. In response to the charge of self-referential incoherence, it is argued that the charge rests on a mistaken understanding of MacIntyre's position and of the nature of justification. In dealing with these arguments, the author hopes to not only vindicate MacIntyre's account of rationality against the charges of some of its recent critics, but also to shed some light on the nature of arguments both for and against relativism and historicism. (shrink)

Kant argues that morality leads to religion, and that religion consists in regarding our moral duties as divine commands. This paper explores a foundational question for Kantian religion: When you think of your duties as divine commands, what exactly are you thinking, and how is that thought consistent with Kant’s own account of the ways that morality is independent from God? I argue that if we assume the Kantian religious person acts out of obedience to God, then her overall outlook (...) will be inconsistent. I then develop an account of regarding duties as divine commands that does not involve acting out of obedience to God. This account, however, faces an objection—that without obedience, one cannot actually be thinking of duties as divine commands. In the final section, I consider this objection and suggest a response. (shrink)

In recent discussions about whether the use of a love pill to enhance love in our romantic relationships is desirable, one argument centres on the question whether this love pill would secure the final value we attribute to love. Sven Nyholm argues that it would not, because one thing we desire for its own sake is to be at the origin of the love others feel for us. In a reply, Hichem Naar argues against Nyholm that a love pill does (...) not need to be incompatible with the final value we attribute to love and that a love pill can have a facilitating role in the creation and sustainment of loving attachment. I think Naar is right but does not address Nyholm's worry completely. I will argue that Naar and Nyholm are speaking of different ends for which the love pill is used as a means, and that whether the love pill would fail or not fail to secure the final value we attribute to love, depends on this particular end. (shrink)

This essay is an analysis of the central arguments in Plato’s Crito. The dialogue shows, in a variety of ways, that the opinion of another person can have practical relevance in one’s deliberations about what to do – e.g. as an argument, as a piece of expert advice, as a threat. Especially important among these forms of practical relevance is the relevance of authoritative commands. In the dialogue, the Laws of Athens argue that Socrates must accept his sentence of death, (...) because he must regard the court’s verdict as a command from a practical authority – the city. The Laws’ arguments rely on special features of authority-reasons that many commentators have overlooked. This article explains why the Law’s arguments are unsuccessful. Finally, it is argued that Socrates’ description of ‘the many’ suggests that the city lacks the deliberative capacity necessary for possessing practical authority. (shrink)

This paper considers the following claim: In order to live well, your first concern must be with yourself. I show how the truth in this claim can be captured by a eudaimonist framework. I distinguish two sorts of self-concern: self-care and self-responsibility. I examine each of these notions. I also consider different senses in which either sort of self-concern might be one’s first concern. I identify the place of each of these ideas in a properly developed eudaimonism. As part of (...) my discussion, I respond to the egoism challenge to eudaimonism, and I outline a thoroughly non-egoistic form of eudaimonism. (shrink)

An increasingly unbridgeable gap exists between the supply and demand of transplantable organs. Human embryonic stem cell technology could solve the organ shortage problem by restoring diseased or damaged tissue across a range of common conditions. However, such technology faces several largely ignored immunological challenges in delivering cell lines to large populations. We address some of these challenges and argue in favor of encouraging contribution or intentional creation of embryos from which widely immunocompatible stem cell lines could be derived. Further, (...) we argue that current immunological constraints in tissue transplantation demand the creation of a global stem cell bank, which may hold particular promise for minority populations and other sub-groups currently marginalized from organ procurement and allocation systems. Finally, we conclude by offering a number of practical and ethically oriented recommendations for constructing a human embryonic stem cell bank that we hope will help solve the ongoing organ shortage problem. (shrink)

The main goal of this paper is to show that there are many phenomena that pertain to the construction of truth-conditional compounds that follow characteristic patterns, and whose explanation requires appealing to knowledge structures organized in specific ways. We review a number of phenomena, ranging from non-homogenous modification and privative modification to polysemy and co-predication that indicate that knowledge structures do play a role in obtaining truth-conditions. After that, we show that several extant accounts that invoke rich lexical meanings to (...) explain such phenomena face problems related to inflexibility and lack of predictive power. We review different ways in which one might react to such problems as regards lexical meanings: go richer, go moderately richer, go thinner, and go moderately thinner. On the face of it, it looks like moderate positions are unstable, given the apparent lack of a clear cutoff point between the semantic and the conceptual, but also that a very thin view and a very rich view may turn out to be indistinguishable in the long run. As far as we can see, the most pressing open questions concern this last issue: can there be a principled semantic/world knowledge distinction? Where could it be drawn: at some upper level (e.g. enriched qualia structures) or at some basic level (e.g. constraints)? How do parsimony considerations affect these two different approaches? A thin meanings approach postulates intermediate representations whose role is not clear in the interpretive process, while a rich meanings approach to lexical meaning seems to duplicate representations: the same representations that are stored in the lexicon would form part of conceptual representations. Both types of parsimony problems would be solved by assuming a direct relation between word forms and (parts of) conceptual or world knowledge, leading to a view that has been attributed to Chomsky (e.g. by Katz 1980) in which there is just syntax and encyclopedic knowledge. (shrink)

Engaging civil society actors as knowledgeable dialogue partners in the development and governance of emerging technologies is a new challenge. The starting point of this paper is the observation that the design and orchestration of current organized interaction events shows limitations, particularly in the articulation of issues and in learning how to address the indeterminacies that go with emerging technologies. This paper uses Dewey’s notion of ‘publics’ and ‘reflective inquiry’ to outline ways of doing better and to develop requirements for (...) a more productive involvement of civil society actors. By studying four novel spaces for interaction in the domain of nanotechnology, this paper examines whether and how elements of Dewey’s thought are visible and under what conditions. One of the main findings is that, in our society, special efforts are needed in order for technology developers and civil society actors to engage in a joint inquiry on emerging nanotechnology. Third persons, like social scientists and philosophers, play a role in this respect in addition to external input such as empirically informed scenarios and somewhat protected spaces. (shrink)

An increasingly unbridgeable gap exists between the supply and demand of transplantable organs. Human embryonic stem cell technology could solve the organ shortage problem by restoring diseased or damaged tissue across a range of common conditions. However, such technology faces several largely ignored immunological challenges in delivering cell lines to large populations. We address some of these challenges and argue in favor of encouraging contribution or intentional creation of embryos from which widely immunocompatible stem cell lines could be derived. Further, (...) we argue that current immunological constraints in tissue transplantation demand the creation of a global stem cell bank, which may hold particular promise for minority populations and other sub-groups currently marginalized from organ procurement and allocation systems. Finally, we conclude by offering a number of practical and ethically oriented recommendations for constructing a human embryonic stem cell bank that we hope will help solve the ongoing organ shortage problem. (shrink)