The mechanisms of longevity have been the subject of investigations for a number of years. Although the role of genetic factors is generally acknowledged, important questions persist regarding the relative impact of environmental exposures, lifestyle characteristics, and genes. The BALSAC population register offers a unique opportunity to study longevity from an intergenerational and genealogical point of view. Individuals from the Saguenay-Lac-St-Jean population who died at age 90 or older between 1950 and 1974 were selected from this database (n = 576), (...) along with a control group of individuals born in the same period who died between 50 and 75 years of age. For these subjects and controls, spouses’ ages at death and parental ages at death and at their birth were investigated using regression analysis. Genealogical reconstructions were carried out for each individual, and various analyses were performed on both groups. Both fathers’ and mothers’ mean ages at death were significantly higher among the longer-lived cases than among controls whereas spouses’ ages at death and parental ages at birth had no effect. Regression analysis confirmed the positive effect of both fathers’ and mothers’ age at death. Mean kinship coefficients for the parents’ generations displayed significant differences, indicating that kinship was higher among subjects than controls (this effect was stronger among the oldest 10% of the subjects). Frequencies and genetic contributions of ancestors were very similar for the two groups, and none of these ancestors appeared more likely to have introduced genetic variants involved in longevity patterns in this French Canadian population. (shrink)

It is widely held that we can obtain beliefs and withhold believing propositions directly by performing an act of will. This thesis is sometimes identified with the view that believing is a basic act, an act which is under our direct control. Descartes holds that the will is limitless in relation to belief acquisition and that we must be directly responsible for our beliefs, especially our false beliefs, for otherwise we could draw the blasphemous conclusion that God is responsible for (...) them. For Descartes and his followers judgment and assent are acts of the will which may be made both when they ought and when they ought not to be made. They are expressions of freedom of the will and as such we are directly responsible for the beliefs we acquire. Other philosophers who seem to espouse volitionalism include Aquinas, Locke, Kierkegaard, Newman, James, Pieper, Chisholm and Meiland. (shrink)

I challenge here the concept of SOC in regard to the question of the consciousness or unconsciousness of logical errors. My commentary offers support for the demonstration of how neuroimaging techniques might be used in the psychology of reasoning to test hypotheses about a potential hierarchy of levels of consciousness (and thus of partial unconsciousness) implemented in different brain networks.

Michaël Crevoisier : Fraichement retraité, vous avez été Maître de conférences au département de philosophie de l’Université de Franche-Comté. Toute votre carrière, mais en réalité déjà vos études, se sera déroulée ici, à Besançon. Je souhaiterais donc commencer par cette ville, cet ancrage. Est-ce que cela revêt une signification particulière pour vous? Et s’il fallait nous le rappeler en quelques mots, qu’avez-vous fait et vécu à Besançon à travers vos travaux philosophiques? Louis Uccian...

Even though the 3Rs are widely accepted as ethical standards when evaluating research projects using animals as experimental subjects, the ethical status of the 3Rs still remains to be clarified. The 3Rs were not derived from any ethical theory, but they represented an attempt to increase humanity to animal experimentation and at the same time to improve validity of scientific data . The aim of the present article was to provide an ethical analysis of the 3Rs through Engelhardt's bioethics theory (...) . The analysis revealed the 3Rs fitted to some extent Engelhardt ethical values. But the analysis also revealed some internal contradictions between the 3Rs and Engelhardt's ethical vaules. Although the 3Rs are still valuable tools in animal ethical evaluation, the present analysis suggests that some ethical issues still remain to be clarified. (shrink)

In this article, we first describe our general inhibitory-control theory and, then, we describe how we have tested its specific hypotheses on reasoning with brain imaging techniques in adults and children. The innovative part of this perspective lies in its attempt to come up with a brain-based synthesis of Jean Piaget’s theory on logical algorithms and Daniel Kahneman’s theory on intuitive heuristics.

The distinguished philosopher Louis Loeb examines the epistemological framework of Scottish philosopher David Hume, as employed in his celebrated work A Treatise of Human Nature. Loeb's project is to advance an integrated interpretation of Hume's accounts of belief and justification. His thesis is that Hume, in his Treatise, has a "stability-based" theory of justification which posits that his belief is justified if it is the result of a belief producing mechanism that engenders stable beliefs. But Loeb argues that the (...) striking corollary to this theory is that no belief generating mechanism is fully stable - or fully justified - for a fully reflective person. This carefully argued and original interpretation of Hume makes sense of seemingly contradictory ideas and will provoke serious discussion among Hume scholars. (shrink)

A translation of the renowned French reference book, Vocabulaire de sciences cognitives , the Dictionary of Cognitive Science presents comprehensive definitions of more than 120 terms. The editor and advisory board of specialists have brought together 60 internationally recognized scholars to give the reader a comprehensive understanding of the most current and dynamic thinking in cognitive science. Topics range from Abduction to Writing, and each entry covers its subject from as many perspectives as possible within the domains of psychology, artificial (...) intelligence, neuroscience, philosophy, and linguistics. This multidisciplinary work is an invaluable resource for all collections. (shrink)

For ecofeminists within academic contexts, the classroom is another "contested terrain "where transformative eco-cultural work should be integrated. In our case, we are a part of communication studies and try to adopt ecofeminist insight as a position for questioning dominant discourses and practices. To do this, we "incorporate popular culture as a serious object of politics and analysis" (Giroux 1997, 148). It is our hope that popular culture can be used as an ecofeminist tool for interrupting hegemonic power relations and (...) encouraging critical-relational consciousness. This paper reports an exploratory effort aimed at combining ecofeminist critiques with popular culture to employ an ecofeminist pedagogy. It begins with an ecofeminist critique of the "animal-industrial-complex" (Noske 1989). In this critique, discursive moral agents are situated within the anthropocentric and androcentric culture (Payne 1994). It then articulates an ecofeminist teaching philosophy and describes how that philosophy was applied in one case using an episode from a prime time television cartoon. Finally, it draws conclusions about what is accomplished through this exploratory case. (shrink)

What explains the existence and persistence of institutions? This article centres on Guala and Hindriks' functionalist theory of institutions, which explains their existence and persistence by their overall beneficial consequences, where these consequences are not the intentional product of individual or collective human decisions. According to them, institutions exist and persist because they generate “cooperative benefits”, through their ability to solve coordination problems. This article aims to show that their theory is lacking in at least three respects. First, indeterminacy in (...) the selection of coordination devices weakens its predictive power. Second, their account relies on an inappropriate conception of the benefits of institutions, which makes it unable to explain why some institutions exist and persist while others do not. Finally, it lacks empirical support from history. (shrink)

Primary progressive aphasia is a clinical syndrome in which patients progressively lose speech and language abilities. Three variants are recognized: logopenic, associated with phonology and/or short-term verbal memory deficits accompanied by left temporo-parietal atrophy; semantic, associated with semantic deficits and anterior temporal lobe atrophy; non-fluent associated with grammar and/or speech-motor deficits and inferior frontal gyrus atrophy. Here, we set out to investigate whether the three variants of PPA can be dissociated based on error patterns in a single language task. We (...) recruited 21 lvPPA, 28 svPPA, and 24 nfvPPA patients, together with 31 healthy controls, and analyzed their performance on an auditory noun-to-verb generation task, which requires auditory analysis of the input, access to and selection of relevant lexical and semantic knowledge, as well as preparation and execution of speech. Task accuracy differed across the three variants and controls, with lvPPA and nfvPPA having the lowest and highest accuracy, respectively. Critically, machine learning analysis of the different error types yielded above-chance classification of patients into their corresponding group. An analysis of the error types revealed clear variant-specific effects: lvPPA patients produced the highest percentage of “not-a-verb” responses and the highest number of semantically related nouns ; in contrast, svPPA patients produced the highest percentage of “unrelated verb” responses and the highest number of light verbs. Taken together, our findings indicate that error patterns in an auditory verb generation task are associated with the breakdown of different neurocognitive mechanisms across PPA variants. Specifically, they corroborate the link between temporo-parietal regions with lexical processing, as well as ATL with semantic processes. These findings illustrate how the analysis of pattern of responses can help PPA phenotyping and heighten diagnostic sensitivity, while providing insights on the neural correlates of different components of language. (shrink)

Three Canadian institutional animal care and use committees were observed over a 1-year period to investigate animal ethical evaluation. While each protocol was evaluated, the observer collected information about the final decision, the type of protocol, and the category of invasiveness. The observer also wrote down verbatim all verbal interventions, which were coded according to the following categories: scientific, technical, politics, human analog, reduction, refinement, and replacement. The data revealed that only 16% of the comments were devoted to the 3 (...) explicit ethical categories and that most of the comments were technical. However, the analysis revealed that ethical concerns were implicit in both scientific and technical comments; either ethical norms had been translated into scientific and technical language, or some of the scientific and technical comments had an impact on the ethical treatment of animals. The results are discussed in relation to previous nonobservational research that identified potential pitfalls and bias in animal ethical evaluation. (shrink)

No figure among the western Marxist theoreticians has loomed larger in the postwar period than Louis Althusser. A rebel against the Catholic tradition in which he was raised, Althusser studied philosophy and later joined both the faculty of the Ecole normal superieure and the French Communist Party in 1948. Viewed as a "structuralist Marxist," Althusser was as much admired for his independence of intellect as he was for his rigorous defense of Marx. The latter was best illustrated in For (...) Marx (1965), and Reading Capital (1968). These works, along with Lenin and Philosophy (1971) had an enormous influence on the New Left of the 1960s and continues to influence modern Marxist scholarship. This classic work, which to date has sold more than 30,000 copies, covers the range of Louis Althusser's interests and contributions in philosophy, economics, psychology, aesthetics, and political science. Marx, in Althusser's view, was subject in his earlier writings to the ruling ideology of his day. Thus for Althusser, the interpretation of Marx involves a repudiation of all efforts to draw from Marx's early writings a view of Marx as a "humanist" and "historicist." Lenin and Philosophy also contains Althusser's essay on Lenin's study of Hegel; a major essay on the state, "Ideology and Ideological State Apparatuses," "Freud and Lacan: A letter on Art in Reply to Andre Daspre," and "Cremonini, Painter of the Abstract." The book opens with a 1968 interview in which Althusser discusses his personal, political, and intellectual history. (shrink)

A compelling idea holds that reality has a layered structure. We often disagree about what inhabits the bottom layer, but we agree that higher up we find chemical, biological, geological, psychological, sociological, economic, /etc./, entities: molecules, human beings, diamonds, mental states, cities, interest rates, and so on. How is this intuitive talk of a layered structure of entities to be understood? Traditionally, philosophers have proposed to understand layered structure in terms of either reduction or supervenience. But these traditional views face (...) well-known problems. A plausible alternative is that layered structure is to be explicated by appeal to explanations of a certain sort, termed / grounding explanations/. Grounding explanations tell us what obtains in virtue of what. Unfortunately, the use of grounding explanations to articulate the layered conception faces a problem, which I call /the collapse/. The collapse turns on the question of how to ground the facts stated by the explanations themselves. In this paper I make a suggestion about how to ground explanations that avoids the collapse. Briefly, the suggestion is that the fact stated by a grounding explanation is grounded in its /explanans/. (shrink)

I challenge two points in Cohen Kadosh & Walsh's (CK & W) argument: First, the definition of abstraction is too restricted; second, the distinction between representations and operations is too clear-cut. For example, taking Jean Piaget's I propose that another way to avoid orthodoxy in the field of numerical cognition is to consider inhibition as an alternative idea of abstraction.

Considérée en sa nature, la syntaxe est d'abord une manière de joindre les mots — et done de les disjoindre les uns des autres — pour former des ensembles significatifs: des textes, des textiles, des tissus. Par ailleurs, la syntaxe interne est cette manière de Her — et de délier done — les éléments d'un mot pour en modifier le sens selon les exigences des besoins particuliers ou des possibilités universelles ou encore selon le marché. De toute façon, cette syntaxe (...) est une grammaire harmonique ou les sons appellent où rappellent les choses, les dissocient ou les composent, les emboîtent ou les déboîtent. (shrink)

DE mon exil, source vive en effet de philosphie, je prends connaissance de la livraison de mars de Dialogue. D'où cette note qui ne se veut pas plus qu'une reaction ad hominem et ad litteram contre toute tentative de delier mesure et philosophic dans l'expression « mesure de la philosophic », ou pour toute position voulant renier ou renverser démesure et philosophic dans l'article « La Démesure de la philosophic ».