What is the nature of children's trust in testimony? Is it based primarily on evidential correlations between statements and facts, as stated by Hume, or does it derive from an interest in the trustworthiness of particular speakers? In this essay, we explore these questions in an effort to understand the developmental course and cognitive bases of children's extensive reliance on testimony. Recent work shows that, from an early age, children monitor the reliability of particular informants, differentiate between those who make (...) true and false claims and keep that differential accuracy in mind when evaluating new information from these people. We argue that this selective trust is likely to involve the mentalistic appraisal of speakers rather than surface generalizations of their behavior. Finally, we review the significance of children's deference to adult authority on issues of naming and categorization. In addition to challenging a purely inductive account of trust, these and other findings reflect a potentially rich set of tools brought by children to the task of learning from people's testimony. (shrink)

Background Informed consent is often cited as the “cornerstone” of research ethics. Its intent is that participants enter research voluntarily, with an understanding of what their participation entails. Despite agreement on the necessity to obtain informed consent in research, opinions vary on the threshold of disclosure necessary and the best method to obtain consent. We aimed to investigate Australian researchers’ views on, and their experiences with, obtaining informed consent. Methods Semi-structured interviews were conducted with 23 researchers from NSW institutions, working (...) in various fields of research. Interviews were analysed and coded to identify themes. Results Researchers reported that consent involved information disclosure, understanding and a voluntary decision. They emphasised the variability of consent interactions, which were dependent on potential participants’ abilities and interests, study complexity and context. All researchers reported providing written information to potential participants, yet questioned the readability and utility of this information. The majority reported using signed consent forms to ‘operationalise’ consent and reported little awareness of, and lack of support in implementing more dynamic informed consent procedures, such as verbal informed consent, that was fit for the purposes of their studies. Views on Human Research Ethics Committees varied. Some reported inconsistent, arduous inputs on the information form and consent process. Others expressed reliance on HRECs for guidance, viewing them as institutional safeguards. Conclusions This study highlights the importance of transparent relationships, both between researchers and participants, and between researchers and HRECs. Where the relationship with study participants was reported as more robust, researchers felt that they were better able to ensure participants made better, more informed decisions. Where the relationship with HRECs was reported as more robust, researchers were more likely to view them as institutional safeguards, rather than as bureaucratic hindrances. Conscientious and mindful researchers are paramount to ensuring the procedure accommodates individual requirements. This study advocates that when designing ethical informed consent practices, researchers should be integrated as autonomous players with a positive input on the process, rather than, in the worst case, predatory recruiters to be curtailed by information forms and oversight. (shrink)

This article presents a systematic review carried out around the development of technologies that have driven military communication, describing the evolution of communication equipment and protocols used throughout history. This work was carried out from the review of 80 articles related to the field of militarycommunications, from which the fundamentals of the different technologies, equipment and means of communication were extracted. It is concluded that technological progress has improved the speed of response in digital signals, has proposed.

The 2006 Centers for Disease Control and Prevention (CDC) revised recommendations for HIV testing in clinical settings contained seven specific changes to how health care facilities should provide HIV testing. These seven elements have been both supported and challenged in the lay and medical literature. Our first paper in BMC Medical Ethics presented an analysis of the three HIV testing procedural changes included in the recommendations. In this paper, we address the four remaining elements that concern HIV screening policy changes: (...) (1) nontargeted HIV screening, (2) making HIV screening similar to screening for other treatable conditions, (3) increasing HIV screening without assured additional funding for linkage to care, and (4) making patients bear the costs of increased HIV screening in health care settings. (shrink)

The American Journal of Bioethics, Volume 12, Issue 4, Page 17-19, April 2012.

David Haig propounds and illustrates the unity of a radically revised set of definitions of the family of terms at the heart of philosophy of cognitive science and mind: information, meaning, interpretation, text, choice, possibility, cause. This biological re-grounding of much-debated concepts yields a bounty of insights into the nature of meaning and life. An interpreter is a mechanism that uses information in choice. The capabilities of the interpreter couple an entropy of inputs to an entropy of outputs is (...) dispelled by observation. The second entropy is dispelled. I propose that an interpreter’s response to inputs meaning of the information for the interpreter. In this conceptual framework, the mechanisms of interpreters provide the much-debated link between Shannon information and semantics. (shrink)

Abstract Gene-selectionists define fundamental terms in non-standard ways. Genes are determinants of difference. Phenotypes are defined as a gene’s effects relative to some alternative whereas the environment is defined as all parts of the world that are shared by the alternatives being compared. Environments choose among phenotypes and thereby choose among genes. By this process, successful gene sequences become stores of information about what works in the environment. The strategic gene is defined as a set of gene tokens that combines (...) ‘actor’ tokens responsible for an effect with ‘recipient’ tokens whose replication is thereby enhanced. This set of tokens can extend across the boundaries of individual organisms, or other levels of selection, as these are traditionally defined. Content Type Journal Article Pages 1-19 DOI 10.1007/s10539-012-9315-5 Authors David Haig, Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, USA Journal Biology and Philosophy Online ISSN 1572-8404 Print ISSN 0169-3867. (shrink)

In an earlier paper I have attempted to show, among other things; that the names of human artifacts and man-devised activities and processes involve in their uses the notion of some end-in-view, function, or use , which partially regulates these uses. In this paper I shall limit myself to a somewhat detailed discussion of one very important class of such common names which requires a separate treatment. I mean art-names.

Programs, policies, and technologies — particularly those concerned with health equity — are often designed with justice envisioned as the end goal. These policies or interventions, however, frequently fail to recognize how the beneficiaries have historically embodied the cumulative effects of marginalization, which undermines the effectiveness of the intended justice. These well-meaning attempts at justice are bounded by greater socio-historical constraints. Bounded justice suggests that it is impossible to attend to fairness, entitlement, and equity when the basic social and physical (...) infrastructures underlying them have been eroded by racism and other historically entrenched isms. Using the case of Brazil’s National Health Policy for the Black Population, this paper proposes that bounded justice can contribute to justice discourses by serving as a concept, a proffering to a multi-disciplinary conceptual framework, and a potential analytic for those interested in the design of policy, technology, and programmatic interventions towards health equity. (shrink)

Competition among scientists for funding, positions and prestige, among other things, is often seen as a salutary driving force in U.S. science. Its effects on scientists, their work and their relationships are seldom considered. Focus-group discussions with 51 mid- and early-career scientists, on which this study is based, reveal a dark side of competition in science. According to these scientists, competition contributes to strategic game-playing in science, a decline in free and open sharing of information and methods, sabotage of others’ (...) ability to use one’s work, interference with peer-review processes, deformation of relationships, and careless or questionable research conduct. When competition is pervasive, such effects may jeopardize the progress, efficiency and integrity of science. (shrink)

This is the second of the four essays in Part II of the book on liberalism and traditionalist education; all four are by authors who would like to find ways for the liberal state to honour the self-definitions of traditional cultures and to find ways of avoiding a confrontation with differences. Melissa Williams examines citizenship as identity in relation to the project of nation-building, the shifting boundaries of citizenship in relation to globalization, citizenship as shared fate, and the role (...) of multicultural education within the view of citizenship-as-shared-fate. She argues the other side of the same coin to that presented by Shelley Burtt in the previous chapter: according to Williams, the liberal state often demands too much in the way of loyalty from traditional groups, and when it does, it runs a strong risk of becoming oppressive and illiberal. Moreover, she holds that there is no need for a single shared identity among citizens of the liberal state. Her conception of people tied together by a shared fate is to this extent compatible with Burtt’s attempt to make liberalism’s commitment to autonomy more hospitable to groups of individuals encumbered by unchosen attachments, but her notion of citizenship as shared fate also goes further than that, and possibly stands in some tension with, Burtt’s view, since it allows and even encourages people to develop primary affiliation to all kind of groups – traditional as well as global. (shrink)

The nature of scientific societies’ relationships with their members limits their ability to promote research integrity. They must therefore leverage their strengths as professional organizations to integrate ethical considerations into their ongoing support of their academic disciplines. This paper suggests five strategies for doing so.

The High Court is taking an increasingly important role in shaping the contours of democracy in Australia. In deciding fundamental democratic questions, does the Court pursue a consistent and overarching democratic vision? Or are its decisions essentially constrained by institutional and practical limitations? Judging Democracy, first published in 2000, addresses this question by examining the Court's recent decisions on human rights, citizenship, native title and separation of powers. It represents the first major political and legal examination of the Court's new (...) jurisprudence and the way it is influencing democracy and the institutions of governance in Australia. A foreword to the book has been written by the former Chief Justice of the High Court, Sir Anthony Mason. (shrink)

Mitochondria exist in large numbers per cell. Therefore, the strength of natural selection on individual mtDNAs for their contribution to cellular fitness is weak whereas the strength of selection in favor of mtDNAs that increase their own replication without regard for cellular functions is strong. This problem has been solved for most mitochondrial genes by their transfer to the nucleus but a few critical genes remain encoded by mtDNA. Organisms manage the evolution of mtDNA to prevent mutational decay of essential (...) services mitochondria provide to their hosts. Bottlenecks of mitochondrial numbers in female germlines increase the homogeneity of mtDNAs within cells and allow intraorganismal selection to eliminate cells with low quality mitochondria. Mechanisms of intracellular “quality control” allow direct selection on the competence of individual mtDNAs. These processes maintain the integrity of mtDNAs within the germline but are inadequate to indefinitely maintain mitochondrial function in somatic cells. (shrink)

John Locke is acknowledged to be one of the theoretical founders of the separation of church and state, a distinguishing feature of modern liberal democracies. Though Locke’s arguments for the merits of such separation have been subject to extensive investigation, his argument for its feasibility has remained relatively unexamined. This article argues that Locke was confident that separation of church and state can successfully be implemented in all times and places because of his epistemological and psychological insights that human beings (...) are moved to act by unease and that separating church and state removes the unease that causes religiously based political instability. We conclude by noting that Locke’s understanding of unease is foundational for his larger ambition to secure political liberty. (shrink)

This article explains the problems with Alan Shewmon’s critique of brain death as a valid sign of human death, beginning with a critical examination of his analogy between brain death and severe spinal cord injury. The article then goes on to assess his broader argument against the necessity of the brain for adult human organismal integration, arguing that he fails to translate correctly from biological to metaphysical claims. Finally, on the basis of a deeper metaphysical analysis, I offer a revised (...) rationale for the validity of the neurological criterion of human death. (shrink)

Democracy is admired for fostering deliberation, debate and innovation. Yet there is also the persistent suspicion that it is anti-intellectual. This article turns to one of the foremost theorists of modern democracy, Alexis de Tocqueville, to assess his contribution to the debate on democratic anti-intellectualism. It argues that Tocqueville denies democracy is anti-intellectual, yet he also claims democracy favours a distinctive intellectual life, informed theoretically by a Cartesian scepticism and practically by the dominance of a practical and commercial perspective in (...) the sciences, arts and literature. The article concludes by examining the technocratic implications of this form of intellectualism for democratic stability and legitimacy. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 33.1 (2000) 74-93 [Access article in PDF] "Lord Over the Children of Pride": The Vaine-Glorious Rhetoric of Hobbes's Leviathan Haig Patapan Hobbes claimed in the Leviathan that he had, by "industrious meditation," discovered the Principles of Reason that would allow Commonwealths to be everlasting. He claimed, in other words, to have solved the political problem (1968, chap. 30, 378). All that was now required was (...) to have his work "fall in the hands of a Soveraign" who would, "in protecting the Publique teaching of it, convert this Truth of Speculation, into Utility of Practice" (chap. 31, 408). Accordingly, an important element of his political solution was the Leviathan itself, a work that would instruct the people in the Essential Rights of Sovereignty (chap. 30, 379). It would seem, then, that the Leviathan is an essential combination of these two aspects of Hobbes's endeavour; it is a work that is intended to reveal and persuade. Therefore, it is appropriate to evaluate his undertaking, not only in terms of its teaching, but also in the success of its rhetorical ambition. 1I argue in this paper that Hobbesian rhetoric is fundamentally determined by his political theory, in particular, by his discovery of the problem of vaine-glory, or pride. Pride poses a political problem because it is a passion that produces an unrealistic estimation of our abilities and therefore ultimately leads to deadly struggles and war. Hobbesian political science attempts to overcome the problem of pride by instituting a Leviathan, a lord over the children of pride. Once we see the nature of the political problem as Hobbes presents it and his proposed solution, the rhetorical character of Hobbes's writings becomes clearer.The extent to which Hobbes relies upon, and in crucial respects departs from, the traditional rhetoric that drew upon Artistotle's Rhetoric and subsequently Cicero's De Inventione and Quintilan's Institutio Oratoria is a complex question. 2 In this paper, I explore the rhetoric of the Leviathan, especially its first part, "On Man," to distinguish the Aristotelian and Ciceronian tradition from what I call Hobbes's Euclidean rhetoric. More [End Page 74] specifically, I argue that the structure and movement of part 1 of the Leviathan can be better understood when it is seen as a direct assault on human pride, a stripping away of all claims that may lead to vaine-glory. It is a step-by-step, Euclidean reductio that attempts to curb the readers' passion of glorying. This argument about the rhetorical character of the first part of the Leviathan has important theoretical consequences: it suggests that Hobbes's influential formulation of power, rights, and justice also had a profoundly rhetorical character.But how persuasive is Hobbes's rhetoric? For reasons noted above, this question goes to the heart of his political theory. The final part of this paper explores the efficacy of the Hobbesian rhetoric of pride and therefore of Hobbesian science. I argue that the rhetorical descent in the first part of the Leviathan, where the truth about human weakness is revealed to the proud, is simultaneously an ascent that acknowledges independence and self-sufficiency of human beings as "self-makers." Thus I argue that, rather than overcoming the problem of pride, Hobbesian political science re-founds it on the bases of rights and the promise of unlimited progress through science and commerce: Hobbes's rhetoric reformulated, but did not solve, the problem of pride. The problem of pride The importance of pride for Hobbes's psychology and political theory is evident from the title and frontispiece of the Leviathan. 3 The Leviathan, according to the Old Testament, is a creature of the Lord, set over the children of pride (Job 41:34). In Hobbes's reformulation, the Leviathan is an artificial body, made by the "Art of man," whose business is Salus Populi or the peoples' safety (1968, "Introduction," 81). Thus, from the beginning, the revolutionary flavour of Hobbes's enterprise is made evident: Man replaces God; pride is a problem of safety... (shrink)

Globalization generates new structures of human interdependence and vulnerability while also posing challenges for models of democracy rooted in territorially bounded states. The diverse phenomena of globalization have stimulated two relatively new branches of political theory: theoretical accounts of the possibilities of democracy beyond the state; and comparative political theory, which aims at bringing non-Western political thought into conversation with the Western traditions that remain dominant in the political theory academy. This article links these two theoretical responses to globalization by (...) showing how comparative political theory can contribute to the emergence of new global “publics” around the common fates that globalization forges across borders. Building on the pragmatist foundations of deliberative democratic theory, it makes a democratic case for comparative political theory as an architecture of translation that helps deliberative publics grow across boundaries of culture. (shrink)

In this essay, I outline fundamental anthropological and moral principles related to human sexuality and gender identity and then apply these principles to analyze and evaluate the views of several authors who attempt to carve out a “middle way” between liberal and traditionalist approaches to these issues. In doing so, I engage especially with the claim that gender dysphoria, rather than being a psychological issue, is a type of biological intersex condition in which one’s “brain sex” is out of line (...) with one’s genital and chromosomal sex. I argue that understanding the human person as a unity of body and soul and recognizing human sexuality as ordered toward the human good of marriage understood as inseparably unitive and procreative reveals the flaws in this position and helps to show why hormonal or surgical gender reassignment therapy is not a medically or ethically appropriate response to gender dysphoria. I also offer an alternative characterization of gender dysphoria and suggestions for responding with true compassion to those who suffer from it. (shrink)

The germ track is the cellular path by which genes are transmitted to future generations whereas somatic cells die with their body and do not leave direct descendants. Transposable elements (TEs) evolve to be silent in somatic cells but active in the germ track. Thus, the performance of most bodily functions by a sequestered soma reduces organismal costs of TEs. Flexible forms of gene regulation are permissible in the soma because of the self‐imposed silence of TEs, but strict licensing of (...) transcription and translation is maintained in the germ track to control proliferation of TEs. Delayed zygotic genome activation (ZGA) and maternally inherited germ granules are adaptations that enhance germ‐track security. Mammalian embryos exhibit very early ZGA associated with extensive mobilization of retroelements. This window of vulnerability to retrotransposition in early embryos is an indirect consequence of evolutionary conflicts within the mammalian genome over postzygotic maternal provisioning. (shrink)

Can ordinary citizens in a democracy evaluate the claims of scientific experts? While a definitive answer must be case by case, some scholars have offered sharply opposed general answers: a skeptical versus an optimistic. The article addresses this basic conflict, arguing that a satisfactory answer requires a first-order engagement in judging the claims of experts which both skeptics and optimists rule out in taking the issue to be one of second-order assessments only. Having argued that such first-order judgments are necessary, (...) it then considers how they are possible, outlining a range of practices and virtues that can inform their success and likelihood, and drawing throughout on ancient Greek insights as well as contemporary social psychology and sociology of knowledge. In conclusion the ethics of democratic judgment so developed is applied to the dramatic conviction of the members of an Italian scientific risk commission in L'Aquila. (shrink)