BackgroundThe preferable position of Deep Brain Stimulation electrodes is proposed to be located in the dorsolateral subthalamic nucleus to improve general motor performance. The optimal DBS electrode localization for the post-operative improvement of balance and gait is unknown.MethodsIn this single-center, retrospective analyses, 66 Parkinson’s disease patients were assessed pre- and post-operatively by using MDS-UPDRS, freezing of gait score, Giladi’s gait and falls questionnaire and Berg balance scale. The clinical outcome was related to the DBS electrode coordinates in x, y, z (...) plane as revealed by image-based reconstruction. Binomial generalized linear mixed models with fixed-effect variables electrode asymmetry, parkinsonian subtype, medication, age class and clinical DBS induced changes were analyzed.ResultsSubthalamic nucleus-deep brain stimulation improved all motor, balance and FoG scores in MED OFF condition, however there were heterogeneous results in MED ON condition. DBS electrode reconstructed coordinates impacted the responsiveness of axial symptoms. FoG and balance responders showed slightly more medially located STN electrode coordinates and less medio-lateral asymmetry of the electrode reconstructed coordinates across hemispheres compared to non-responders.ConclusionDeep brain stimulation electrode reconstructed coordinates, particularly electrode asymmetry on the medio-lateral axis affected the post-operative responsiveness of balance and FoG symptoms in PD patients. (shrink)

A persistent problem in the dominant agricultural development model is the imposition of technologies without regard to local processes and cultures. Even with the recent shift towards sustainability and agroecology, initiatives continue to overlook local knowledge. In this article we provide analysis of agroecological soil management in the Maya-Achi territory of Guatemala. The Achí, subject to five decades of interventions and development, present an interesting case study for assessing the complementarities and tensions between traditional, generally preventative practices and external initiatives (...) which tend to be curative. Our findings reveal a complex farming system that continues to rely on ancestral knowledge and practices, many of which display a high potential for sustainability and are deeply embedded in local culture. While some new practices have been incorporated into the traditional system, abandonment rates are high, and some extension methods have been paternalistic. The Achí are thirsty for new ideas to help them confront their current, unprecedented challenges. However, future collaborations should be built on existing local knowledge, which has contributed to the development of preventative and restorative practices still in use. Introduced technologies must coincide with local needs and socioecological context in a manner that encourages beneficial synergies, as well as horizontal learning/teaching processes. (shrink)

Gestures—hand movements that accompany speech and express ideas—can help children learn how to solve problems, flexibly generalize learning to novel problem‐solving contexts, and retain what they have learned. But does it matter who is doing the gesturing? We know that producing gesture leads to better comprehension of a message than watching someone else produce gesture. But we do not know how producing versus observing gesture impacts deeper learning outcomes such as generalization and retention across time. Moreover, not all children benefit (...) equally from gesture instruction, suggesting that there are individual differences that may play a role in who learns from gesture. Here, we consider two factors that might impact whether gesture leads to learning, generalization, and retention after mathematical instruction: (1) whether children see gesture or do gesture and (2) whether a child spontaneously gestures before instruction when explaining their problem‐solving reasoning. For children who spontaneously gestured before instruction, both doing and seeing gesture led to better generalization and retention of the knowledge gained than a comparison manipulative action. For children who did not spontaneously gesture before instruction, doing gesture was less effective than the comparison action for learning, generalization, and retention. Importantly, this learning deficit was specific to gesture, as these children did benefit from doing the comparison manipulative action. Our findings are the first evidence that a child's use of a particular representational format for communication (gesture) directly predicts that child's propensity to learn from using the same representational format. (shrink)

El presente trabajo busca las ventajas de articular la inducción y la analogía con las éticas aplicadas en proyectos socioeducativos. La revisión de artículos muestra que en los proyectos sociales predominan las éticas principialistas, a las que subyace una lógica deductiva, pero algunosestudios revelan éticas aplicadas de corte dialógico y crítico estructuradas con la inducción y la analogía. Se examinan posiciones teóricas sobre el estatuto de las éticas aplicadas, confirmando quela inducción y la analogía están presentes, tanto en la casuística (...) que culmina en la construcciónde máximas o criterios prudenciales como en procedimientos que exigen la participación de losinvolucrados en cada caso concreto, y en el círculo de la hermenéutica crítica con sus dialécticas. Mediante un procedimiento analítico-sintético se examinan 12 proyectos socioeducativos realizados en modalidad no formal. Como resultado, se distinguen cuatro combinaciones: 1) ética prescriptiva y lógica deductiva, 2) ética del reconocimiento y lógicas alternadas, 3) ética dialógica y lógica deldescubrimiento y 4) ética prudencial de la hermenéutica crítica y lógica dialéctica. Se concluye que, al incluir la inducción y la analogía en las éticas aplicadas en proyectos socioeducativos,se contribuye a la mejora de los aprendizajes y a la producción de pautas de comportamiento yconvicciones morales acordes con el contexto respectivo. (shrink)

Bilder in Kunst und Wissenschaft sind Orte des Denkens und Forschens.

The question of whether it is ever permissible to believe on insufficient evidence has once again become a live question. Greater attention is now being paid to practical dimensions of belief, namely issues related to epistemic virtue, doxastic responsibility, and voluntarism. In this book, McCormick argues that the standards used to evaluate beliefs are not isolated from other evaluative domains. The ultimate criteria for assessing beliefs are the same as those for assessing action because beliefs and actions are both products (...) of agency. Two important implications of this thesis, both of which deviate from the dominant view in contemporary philosophy, are 1) it can be permissible to believe for non-evidential reasons, and 2) we have a robust control over many of our beliefs, a control sufficient to ground attributions of responsibility for belief. (shrink)

A new, social epistemology of science that addresses practical as well as theoretical concerns.

How is medical knowledge made? There have been radical changes in recent decades, through new methods such as consensus conferences, evidence-based medicine, translational medicine, and narrative medicine. Miriam Solomon explores their origins, aims, and epistemic strengths and weaknesses; and she offers a pluralistic approach for the future.

In this paper, I begin by defending permissivism: the claim that, sometimes, there is more than one way to rationally respond to a given body of evidence. Then I argue that, if we accept permissivism, certain worries that arise as a result of learning that our beliefs were caused by the communities we grew up in, the schools we went to, or other irrelevant influences dissipate. The basic strategy is as follows: First, I try to pinpoint what makes irrelevant influences (...) worrying and I come up with two candidate principles. I then argue that one principle should be rejected because it is inconsistent with permissivism. The principle we should accept implies that it is sometimes rational to maintain our beliefs, even upon learning that they were caused by irrelevant influences. (shrink)

This book summarizes the intense research that the author performed for his Ph.D. thesis , revised and with the addition of an intuitionistic critique of Husserl's concept of number. His starting point consisted of a double conviction: 1) Brouwerian intuitionism is a valid way of doing mathematics but is grounded on a weak philosophy; 2) Husserlian phenomenology can provide a suitable philosophical ground for intuitionism. In order to let intuitionism and phenomenology match, he had to solve in general two problems: (...) 1) the question of the reciprocal indifference that the authors had toward each other's theorizing which indeed they knew; 2) Husserl's general attitude of accepting classical mathematics, which contrasts with the critical attitude of the intuitionists.Moreover, in the specific case focused on by this book—concerning choice sequences, that is, sequences that can be completely lawless and that were admitted as mathematical entities by Brouwer—van Atten had to handle a further problem: such sequences do not fit the characteristic of omnitemporality that the late Husserl seemed to consider a necessary attribute of entities if they were to be considered mathematical. In as far as they are lawless we cannot predict at any moment how they will develop in the future, hence they are not determined at any particular time—they will be determined only in the future.Let us begin with van Atten's first conviction, i.e., that Brouwerian intuitionism is grounded on a weak philosophy. We have to recall that Brouwer provided a mystical attitude for proposing his intuitionism: man can obtain happiness only by keeping himself closed inside the inner Self. Any attempted movement towards the exterior world is a source of pain: in particular language and the sciences. Mathematics, in order to be morally acceptable …. (shrink)

Many studies show a developmental advantage for transitive sentences with familiar verbs over those with novel verbs. It might be that once familiar verbs become entrenched in particular constructions, they would be more difficult to understand (than would novel verbs) in non-prototypical constructions. We provide support for this hypothesis investigating German children using a forced-choice pointing paradigm with reversed agent-patient roles. We tested active transitive verbs in study 1. The 2-year olds were better with familiar than novel verbs, while the (...) 2½-year olds pointed correctly for both. In study 2, we tested passives: 2½-year olds were significantly below chance for familiar verbs and at chance for novel verbs, supporting the hypothesis that the entrenchment of the familiar verbs in the active transitive voice was interfering with interpreting them in the passive voice construction. The 3½-year olds were also at chance for novel verbs but above chance with familiar verbs. We interpret this as reflecting a lessening of the verb-in-construction entrenchment as the child develops knowledge that particular verbs can occur in a range of constructions. The 4½-year olds were above chance for both familiar and novel verbs. We discuss our findings in terms of the relative entrenchment of lexical and syntactic information and to interference between them. (shrink)

For the last forty years, two claims have been at the core of disputes about scientific change: that scientists reason rationally and that science is progressive. For most of this time discussions were polarized between philosophers, who defended traditional Enlightenment ideas about rationality and progress, and sociologists, who espoused relativism and constructivism. Recently, creative new ideas going beyond the polarized positions have come from the history of science, feminist criticism of science, psychology of science, and anthropology of science. Addressing the (...) traditional arguments as well as building on these new ideas, Miriam Solomon constructs a new epistemology of science. After discussions of the nature of empirical success and its relation to truth, Solomon offers a new, social account of scientific rationality. She shows that the pursuit of empirical success and truth can be consistent with both dissent and consensus, and that the distinction between dissent and consensus is of little epistemic significance. In building this social epistemology of science, she shows that scientific communities are not merely the locus of distributed expert knowledge and a resource for criticism but also the site of distributed decision making. Throughout, she illustrates her ideas with case studies from late-nineteenth- and twentieth-century physical and life sciences. Replacing the traditional focus on methods and heuristics to be applied by individual scientists, Solomon emphasizes science funding, administration, and policy. One of her goals is to have a positive influence on scientific decision making through practical social recommendations. (shrink)

I investigate what we mean when we hold people responsible for beliefs. I begin by outlining a puzzle concerning our ordinary judgments about beliefs and briefly survey and critique some common responses to the puzzle. I then present my response where I argue a sense needs to be articulated in which we do have a kind of control over our beliefs if our practice of attributing responsibility for beliefs is appropriate. In developing this notion of doxastic control, I draw from (...) John Fischer's discussions of “guidance control”. A central feature of this kind of control is the idea of “ownership”. I argue that we can own our beliefs and that we expect each other to do so. We take responsibility for our beliefs and taking responsibility includes taking control of them. I end by considering objections to my view as well as some implications of it. (shrink)

Ruim tweehonderd jaar geleden riep de Duitse filosoof Immanuel Kant de mens op zich te bevrijden van dogma's en slaafse volgzaamheid, van de macht van de kerk en van de macht der gewoonte. De ware Verlichting is volgens hem "het uittreden van de mens uit de onmondigheid waaraan hij zelf schuldig is". Filosoof Miriam Rasch vraagt zich af hoe dit moet, autonoom zijn in een tijd waarin Facebook beweert je beter te kennen dan je eigen moeder. Ze zoekt een (...) antwoord op de vraag of wij onszelf nog wel autonoom kunnen maken, en of we dit zouden moeten willen. Want wat is er eigenlijk zo erg aan algoritmes die beter weten dan wijzelf wat goed voor ons is? En is autonomie niet een verkapte vorm van egoïsme? Rasch zoekt scherp, open en geestig naar antwoorden op vragen die je niet durft te stellen omdat een ander dat vast beter kan. En zo gidst zij zichzelf en jou naar de overtuiging dat je in control bent."---Publisher information. (shrink)

Evidence-Based Medicine (EBM) developed from the work of clinical epidemiologists at McMaster University and Oxford University in the 1970s and 1980s and self-consciously presented itself as a "new paradigm" called "evidence-based medicine" in the early 1990s. The techniques of the randomized controlled trial, systematic review and meta-analysis have produced an extensive and powerful body of research. They have also generated a critical literature that raises general concerns about its methods. This paper is a systematic review of the critical literature. It (...) finds the description of EBM as a Kuhnian paradigm helpful and worth taking further. Three kinds of criticism are evaluated in detail: criticisms of procedural aspects of EBM (especially from Cartwright, Worrall and Howick), data showing the greater than expected fallibility of EBM (Ioaanidis and others), and concerns that EBM is incomplete as a philosophy of science (Ashcroft and others). The paper recommends a more instrumental or pragmatic approach to EBM, in which any ranking of evidence is done by reference to the actual, rather than the theoretically expected, reliability of results. Emphasis on EBM has eclipsed other necessary research methods in medicine. With the recent emphasis on translational medicine, we are seeing a restoration of the recognition that clinical research requires an engagement with basic theory (e.g. physiological, genetic, biochemical) and a range of empirical techniques such as bedside observation, laboratory and animal studies. EBM works best when used in this context. (shrink)

Jacqueline Fawcett's nursing metaparadigm—the domains of person, health, environment, and nursing—remains popular in nursing curricula, despite having been repeatedly challenged as a logical philosophy of nursing. Fawcett appropriated the word “metaparadigm” (indirectly) from Margaret Masterman and Thomas Kuhn as a devise that allowed her to organize then‐current areas of nursing interest into a philosophical “hierarchy of knowledge,” and thereby claim nursing inquiry and practice as rigorously “scientific.” Scholars have consistently rejected the logic of Fawcett's metaparadigm, but have not yet proposed (...) a substantially agreed‐upon alternative. Through an analysis of articles introducing and critiquing Fawcett's metaparadigm, I argue for a re‐conceptualized metaparadigm that articulates nursing's ontology. What exists for the nursing discipline are not already‐demarcated metaparadigm domains, but rather interdependent, dynamic relations that constitute people, including nurses, in their health/environment circumstance. The nursing discipline aims to skillfully access this dynamic relationality as the basis for action and reflection to produce both positive health trajectories and knowledge that facilitates future action and reflection. Further inquiry into the onto‐epistemology of nursing will produce a more robust understanding of nursing practice, science, and philosophy, and clarify its unique contribution to health and healthcare. (shrink)

The Queen's College, Oxford, UK In his article `Facts and Principles', G.A. Cohen attempts to refute constructivist approaches to justification by showing that, contrary to what their proponents claim, fundamental normative principles are fact- in sensitive. We argue that Cohen's `fact-insensitivity thesis' does not provide a successful refutation of constructivism because it pertains to an area of meta-ethics which differs from the one tackled by constructivists. While Cohen's thesis concerns the logical structure of normative principles, constructivists ask how normative principles (...) should be justified . In particular, their claim that justified fundamental normative principles are fact-sensitive follows from a commitment to agnosticism about the existence of objective moral facts. We therefore conclude that, in order to refute constructivism, Cohen would have to address questions of justification, and take a stand on those long-standing meta-ethical debates about the ontological status of moral notions (for example, realism versus anti-realism) with respect to which he himself wants to remain agnostic. Key Words: John Rawls • normative justification • realism versus anti-realism • methodological versus substantive principles. (shrink)

This article summarizes a virtual live‐streamed panel event that occurred in August 2020 and was cosponsored by the International Philosophy of Nursing Society (IPONS) and the University of California, Irvine's Center for Nursing Philosophy. The event consisted of a series of three self‐contained panel discussions focusing on the past, present and future of IPONS and was moderated by the current Chair of IPONS, Catherine Green. The first panel discussion explored the history of IPONS and the journal Nursing Philosophy. The second (...) panel involved a reflection on the challenges of doing nursing philosophy in a research‐intensive context of a Canadian university and the history and current movements in nursing philosophy in the Nordic countries. The final panel involved presentations on the future potential for philosophy in/and for nursing, the critical connections between nursing philosophy and nursing theory, dismantling racism in nursing and the potential for process philosophy to help explore nursing's unique efficacy in creating possibilities for health. The panels were followed by a lively Q&A session with participants, of which there were 252 registrants from across the globe. The event underscored the wide and diverse interests of nurses in philosophical discussion and the need for more virtual events and other connective modalities bringing nurses together to discuss and analyze the value and potential of philosophy to better understand and advance nursing theory and practice. (shrink)

The American Journal of Bioethics, Volume 11, Issue 8, Page 50-52, August 2011.

Dictionaries have long been seen as an essential contribution by linguists to work on endangered languages. We report on preliminary investigations of actual dictionary usage and usability by 76 speakers, semi-speakers and learners of Australian Aboriginal languages. The dictionaries include: electronic and printed bilingual Warlpiri-English dictionaries, a printed trilingual Alawa-Kriol- English dictionary, and a printed bilingual Warumungu-English dictionary. We examine competing demands for completeness of coverage and ease of access, and focus on the prospects of electronic dictionaries for solving many (...) traditional problems, based in particular on observations on the usability of a prototype interface developed in our project. The flexibility of computer interfaces can help accommodate different needs including those of speakers with emerging literacy skills, but they are not useful in communities where computer access is generally unavailable. (shrink)

The ArgumentThis paper describes the way in which a simple device, the pregnancy wheel, has been used by the medical profession to impose a new way of measuring and experiencing pregnancy.The change involves counting in weeks instead of counting in months and it is gradually replacing a commonsensical method that had deep physiological and cultural roots. In contrast, the medical methodology of counting forty weeks is more complicated and lacks direct connections to the events of pregnancyIn the encounter between the (...) doctor and the pregnant woman the pregnancy wheel has a variety of uses, among them determinations of the age and estimated size of the fetus.It plays an additional role, however, in the medicalization of pregnancy by providing the doctor with privileged information. It also influences modes of thinking through the way in which it deals with the question of the beginning of pregnancy, a question that has clear moral implications. (shrink)

The publishing industry has a variety of gatekeepers that play a role in deciding which works become books. This article acknowledges the main gatekeepers as the agent and publishers, but also draws attention to the author, who is the first gatekeeper, and the reader, who is the last. The connections between gatekeepers highlight the role of power in these positions. Using Foucault’s theories of archaeology and genealogy, this article argues that positions within the industry provide space for the gatekeepers to (...) say what works deserve to be published. In doing so it highlights the dynamic flow of power, which rises from the bottom and provides a hierarchical structure within the industry. (shrink)

Written by Derrida scholars, philosophers, and classicists, Derrida and Antiquity analyses a dialogue with the ancient world in the work of one of the greatest ...

The thought of the ancient atomists about the activity of the soul in the body is an important chapter in the history of reflection on the soul in ancient philosophy. A review of testimonies and fragments attributed to Democritus of Abdera shows its singular conception of the soul as a complex network of transactions through which it exercises, inside compound bodies, its role in driving principle of beings animated. These texts show the tension and dynamism that characterize the activity of (...) the soul and especially the close relationship between the activities of perceiving and thinking, essential activities to the economy of living beings, now for what is the management of biological life, now in terms of knowledge and human action. What we propose here is to examine how Democritus conceived the activity of the soul in its complexity and the various operations through which it accomplishes its function in the animation and the maintenance of life of animate beings, and particularly of human life. To do this, we will take as a basis the testimonies referred to the nature of the soul – especially the testimony of Aristotle and his disciples and commentators – and then examine the activities through which proceeds its role of motor principle, namely the sensations and the intellection. And, finally, we intend to demonstrate that these operations should not be considered, in the context of atomist thought, as two independent and opposed faculties or activities, but as two different levels or degree, contiguous and complementary, of one and the same activity. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Hume on Natural Belief and Original Principles Miriam McCormick David Hume discusses anumber ofimportantbeliefs that, althoughhe himselfnever uses the term, commentators have come to call "natural beUefs." These beliefs cannotbejustified rationally but are impossible to give up. They differ from irrational beliefs because no amount of reasoning can eliminate them. There is general agreement that such a class of beliefs exists for Hume. There is differing opinion, however, (...) concerning which beliefs count as "natural." In particular, there has been much debate as to whether beliefin God is "natural" for Hume. Much of this disagreement concerning natural beliefs arises because not enough attention is paid to the different uses of"natural" in Hume. On his analysis, certain characteristics may be called "natural" insofar as their causes are found in human nature. These characteristics can be explained by reference to what Hume calls the original principles ofhuman nature. But they need not be necessary or unavoidable. It is only the original principles themselves, for Hume, that are universal and necessary for all human beings. And it is only those beliefs which necessarily result from original principles that are "natural" in a second sense: these beliefs are, according to Hume, "inseparable from the species." Only beliefs which are natural in this second sense are indispensable despite their lack ofrational grounds. Certain other beliefs, such as belief in God, are "natural" in some weaker sense, but are often taken to be "natural" in this second sense. My aim is to distinguish the different senses of"natural" for Hume and so determine which beliefs are "natural" in which senses. Natural belief Norman Kemp Smith was the first to discuss the existence ofa special class of beliefs in Hume.1 Kemp Smith first uses the term "natural beUef" in reference to the beliefin the existence ofbody. This belief, he says, is a natural belief"due to the ultimate instincts or propensities that constitute our human nature" (Kemp Smith, 151). Furthermore, this particularbeUefis not founded on reason or sense experience, yet no amount ofreasoning will cause us to give it up.2 "Certain beliefs or judgments," says Kemp Smith, "can be shown to be 'natural', 'inevitable', indispensable' and are thus removed beyond the reach of sceptical doubt" (p. 152). Two other beliefs which Kemp Smith says Volume XLX Number 1 103 MIRIAM McCORMICK Hume considere natural are belief in causal action and belief in the identity or unity ofthe self. The primary purpose of Kemp Smith's article is to demonstrate "that the establishment of a purely naturalistic conception ofhuman nature by the thorough subordination ofreason to feeling and instinct is a determining factor in Hume's philosophy" (p. 150). He developed this thesis in reaction to T. H. Green and other commentators who had claimed that Hume "merely develops to a sceptical conclusion the principles which he inherits from Locke and Berkeley" (Kemp Smith, 149). The discussion of "natural belief " is meant to show that Green is mistaken when he claims that Hume denies the existence of the external world and ofthe self. It is true that Hume says reason will not show us that such things exist. But because reason is not supreme for Hume, says Kemp Smith, we need not worry that such beliefs are not justified. Because Hume does not encourage us to give up such fundamental beliefs or even think that such an enterprise is possible, Kemp Smith maintains that, rather than being sceptical about such beliefs, Hume defends them from sceptical attack. There are certain behefs that it makes no sense to question. The doctrine of natural belief serves as an illustration of Kemp Smith's claim that Hume subordinates reason to feeling and instinct. Because his discussion òf "natural belief" is used mainly to illustrate a particular point, Kemp Smith does little more than offer a description of such beliefs. He tells us that these beliefs are inevitable and indispensable, but he does not indicate how one determines which beliefs are natural. Criteria are given for what Hume counts as a natural belief, but the means for determining ifa belief satisfies these criteria are not offered. With the publication of R. J. Butler's article, "Natural Belief and the Enigma... (shrink)

Embodied approaches in cognitive science hold that the body is crucial for cognition. What this claim amounts to, however, still remains unclear. This paper contributes to its clarification by confronting three ways of understanding embodiment—the sensorimotor approach, extended cognition and enactivism—with Locked-in syndrome. LIS is a case of severe global paralysis in which patients are unable to move and yet largely remain cognitively intact. We propose that LIS poses a challenge to embodied approaches to cognition requiring them to make explicit (...) the notion of embodiment they defend and its role for cognition. We argue that the sensorimotor and the extended functionalist approaches either fall short of accounting for cognition in LIS from an embodied perspective or do it too broadly by relegating the body only to a historical role. Enactivism conceives of the body as autonomous system and of cognition as sense-making. From this perspective embodiment is not equated with bodily movement but with forms of agency that do not disappear with body paralysis. Enactivism offers a clarifying perspective on embodiment and thus currently appears to be the framework in embodied cognition best suited to address the challenge posed by LIS. (shrink)

Improving human characteristics goes beyond compensating for an impairment. This book explores the rich and complex relationship between enhancement and impairment, showing that the study of disability offers new ways of thinking about the social and ethical implications of improving the human condition.

REVIEW ESSAY The minimal self needs a social update Self and other: Exploring subjectivity, empathy, and shame, by Dan Zahavi, Oxford, Oxford University Press, 2015, 304 pp.